Pub Date : 2023-03-11DOI: 10.48036/apims.v19i1.727
Muhammad Owais, Amjad Ali, Muhammad Adeel, Ambreen Haider, Ashok Kumar, Marvi Nawaz
Objective: To determine the association between smoking and in-hospital outcomes in patients presented with ST-Elevation Myocardial Infarction undergoing primary percutaneous coronary intervention (PCI). Methodology: This prospective cohort study was conducted at Department of Cardiology, National Institute of Cardiovascular Disease (NICVD), Karachi, from November 9, 2020 to May 8, 2021. All the patients (current smoker, ex-smoker and non-smoker) with age 18 years to 85 years, both gender, patients diagnosed with STEMI in accordance with operational definition and underwent primary PCI were included. Patients diagnosed with ST-Elevation Myocardial Infarction were divided into two groups, expose (smoker) and unexposed (nonsmoker). Before PPCI demographic detail were noted and body mass index was calculated after management of STEMI then PCI was performed. In hospital outcome i.e. heart failure, in-hospital mortality and transient ischemic attack were assessed within 30 days of hospital stay after PCI. All the collected data were entered into the proforma. Results: Mean ±SD of age in exposed group was 56.5±11.8 and non-exposed group was 57.7±12.1 years. In group wise distribution of gender, 82 (70.7%) males and 34 (29.3%) females were enrolled in exposed group and 80 (68.9%) males and 36 (31.1%) females were included in non-exposed group. Risk of heart failure and transient ischemic attack were 1.4 and 5.0 times more likely in exposed as compared to unexposed with [Relative Risk 1.444 and 5.0 respectively. While risk of mortality was 0.2 times less likely in exposed as compared to unexposed with [Relative Risk 0.222] and P value was found to be as significant i.e. (P=0.030). Conclusion: It is to be concluded that significant risk of heart failure and transient ischemic attack were noted in exposed as compared to unexposed and vice versa in case of mortality, but we cannot rule out residual confounders.
{"title":"In Hospital Outcome Among Smoker and Nonsmoker Patients Presented with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention","authors":"Muhammad Owais, Amjad Ali, Muhammad Adeel, Ambreen Haider, Ashok Kumar, Marvi Nawaz","doi":"10.48036/apims.v19i1.727","DOIUrl":"https://doi.org/10.48036/apims.v19i1.727","url":null,"abstract":"Objective: To determine the association between smoking and in-hospital outcomes in patients presented with ST-Elevation Myocardial Infarction undergoing primary percutaneous coronary intervention (PCI). Methodology: This prospective cohort study was conducted at Department of Cardiology, National Institute of Cardiovascular Disease (NICVD), Karachi, from November 9, 2020 to May 8, 2021. All the patients (current smoker, ex-smoker and non-smoker) with age 18 years to 85 years, both gender, patients diagnosed with STEMI in accordance with operational definition and underwent primary PCI were included. Patients diagnosed with ST-Elevation Myocardial Infarction were divided into two groups, expose (smoker) and unexposed (nonsmoker). Before PPCI demographic detail were noted and body mass index was calculated after management of STEMI then PCI was performed. In hospital outcome i.e. heart failure, in-hospital mortality and transient ischemic attack were assessed within 30 days of hospital stay after PCI. All the collected data were entered into the proforma. Results: Mean ±SD of age in exposed group was 56.5±11.8 and non-exposed group was 57.7±12.1 years. In group wise distribution of gender, 82 (70.7%) males and 34 (29.3%) females were enrolled in exposed group and 80 (68.9%) males and 36 (31.1%) females were included in non-exposed group. Risk of heart failure and transient ischemic attack were 1.4 and 5.0 times more likely in exposed as compared to unexposed with [Relative Risk 1.444 and 5.0 respectively. While risk of mortality was 0.2 times less likely in exposed as compared to unexposed with [Relative Risk 0.222] and P value was found to be as significant i.e. (P=0.030). Conclusion: It is to be concluded that significant risk of heart failure and transient ischemic attack were noted in exposed as compared to unexposed and vice versa in case of mortality, but we cannot rule out residual confounders.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115771157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-11DOI: 10.48036/apims.v19i1.503
A. Sultan, M. Shabbir, N. Arshad, Iram Shafee, Anam Naz, M. Hanif
Objectives: To evaluate and find the correlation of balance and functional ankle instability in elderly women. Methodology: A cross-sectional correlation study was conducted from June 2020 to December 2020, in which 61 participants (i.e., elderly women) were included. In the selected old age homes the self-reported questionnaire (Identification of Functional Ankle Instability [IdFAI]) had been distributed to the participants fulfilling the inclusion criteria as hand-outs and the performance-based questionnaire (Performance Oriented Mobility Assessment [POMA]) have been assessed and filled by the researcher. Chi square was used for associations and Pearson correlation for balance score and functional instability score. Results: The mean age of the participants was 64.89±4.30 years. According to the result of Tinetti Balance score, 31.1% elderly women with low risk of fall, medium risk of fall was 32.8% whereas with high risk of fall was 36.1%. The IdFAI showed, elderly women with Ankle Instability 62.3% while elderly women with No Ankle Instability were 37.7%. There was negative (inverse) Pearson linear correlation (r = -0.550) between age and balance (p ≤ 0.05) which means when the age increases, the balance decreases and also a weak association between age and functional ankle instability (p ≥ 0.05). Conclusion: This study concluded that there was not adequate evidence to propose an association between Balance and self-reported functional ankle instability.
{"title":"Correlation of Balance and Functional Ankle Instability in Elderly Women","authors":"A. Sultan, M. Shabbir, N. Arshad, Iram Shafee, Anam Naz, M. Hanif","doi":"10.48036/apims.v19i1.503","DOIUrl":"https://doi.org/10.48036/apims.v19i1.503","url":null,"abstract":"Objectives: To evaluate and find the correlation of balance and functional ankle instability in elderly women. Methodology: A cross-sectional correlation study was conducted from June 2020 to December 2020, in which 61 participants (i.e., elderly women) were included. In the selected old age homes the self-reported questionnaire (Identification of Functional Ankle Instability [IdFAI]) had been distributed to the participants fulfilling the inclusion criteria as hand-outs and the performance-based questionnaire (Performance Oriented Mobility Assessment [POMA]) have been assessed and filled by the researcher. Chi square was used for associations and Pearson correlation for balance score and functional instability score.\u0000Results: The mean age of the participants was 64.89±4.30 years. According to the result of Tinetti Balance score, 31.1% elderly women with low risk of fall, medium risk of fall was 32.8% whereas with high risk of fall was 36.1%. The IdFAI showed, elderly women with Ankle Instability 62.3% while elderly women with No Ankle Instability were 37.7%. There was negative (inverse) Pearson linear correlation (r = -0.550) between age and balance (p ≤ 0.05) which means when the age increases, the balance decreases and also a weak association between age and functional ankle instability (p ≥ 0.05).\u0000Conclusion: This study concluded that there was not adequate evidence to propose an association between Balance and self-reported functional ankle instability.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130309371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-11DOI: 10.48036/apims.v19i1.649
Awais Tahir, Uzma Abid, Iffat Batool, N. Zaman, N. Ahmad, Sumaira Khaleel
Objective: To determine accuracy of cord blood bilirubin in identifying significant neonatal hyperbilirubinemia. Methodology: A Cross sectional study was conducted in Pediatric department of Fauji Foundation Hospital Rawalpindi from Jan.2019 to June 2019. Cord blood samples were sent for the blood group and bilirubin levels. Neonates with cord bilirubin level > 2mg/dl and < 5 mg/dl were enrolled and admitted for 3 days and serum bilirubin level were done on 3rd day. Those developing significant hyperbilirubinemia were further investigated for hemoglobin, reticulocyte count, Coomb’s test and other causes. Results: Total 74 newborns at >35 weeks of gestation were included in the study of which 35 (47.3%) were male and 39 (52.7%) were female (male: female: 1:1.1). The data was analyzed using SPSS 17. At 3rd day of life mean ± SD cord blood bilirubin was 8.4 ± 2.7 mg/dl, mean direct bilirubin was 1.6 ± 0.9 mg/dl and mean indirect bilirubin was 6.8 ± 2.3mg/dl. Significant hyperbilirubinemia developed in 16 (21.6%) newborns at >35 weeks of gestation, who had a cord blood bilirubin level of > 2 mg/dl, so that the accuracy of cord blood bilirubin level (true positives) in determining significant hyperbilirubinemia was 21.6%. Conclusion: Cord blood bilirubin level >2mg/dl in all healthy term newborns predicts significant hyperbilirubinemia.
{"title":"Umbilical Cord Blood Bilirubin and Determination of Neonatal Hyperbilirubinemia","authors":"Awais Tahir, Uzma Abid, Iffat Batool, N. Zaman, N. Ahmad, Sumaira Khaleel","doi":"10.48036/apims.v19i1.649","DOIUrl":"https://doi.org/10.48036/apims.v19i1.649","url":null,"abstract":"Objective: To determine accuracy of cord blood bilirubin in identifying significant neonatal hyperbilirubinemia.\u0000Methodology: A Cross sectional study was conducted in Pediatric department of Fauji Foundation Hospital Rawalpindi from Jan.2019 to June 2019. Cord blood samples were sent for the blood group and bilirubin levels. Neonates with cord bilirubin level > 2mg/dl and < 5 mg/dl were enrolled and admitted for 3 days and serum bilirubin level were done on 3rd day. Those developing significant hyperbilirubinemia were further investigated for hemoglobin, reticulocyte count, Coomb’s test and other causes.\u0000Results: Total 74 newborns at >35 weeks of gestation were included in the study of which 35 (47.3%) were male and 39 (52.7%) were female (male: female: 1:1.1). The data was analyzed using SPSS 17. At 3rd day of life mean ± SD cord blood bilirubin was 8.4 ± 2.7 mg/dl, mean direct bilirubin was 1.6 ± 0.9 mg/dl and mean indirect bilirubin was 6.8 ± 2.3mg/dl. Significant hyperbilirubinemia developed in 16 (21.6%) newborns at >35 weeks of gestation, who had a cord blood bilirubin level of > 2 mg/dl, so that the accuracy of cord blood bilirubin level (true positives) in determining significant hyperbilirubinemia was 21.6%.\u0000Conclusion: Cord blood bilirubin level >2mg/dl in all healthy term newborns predicts significant hyperbilirubinemia.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"28 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120859659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-11DOI: 10.48036/apims.v19i1.558
Fahad Nawaz Khan, Ali Shami, Muhammad Hanif, Yasir Farhan, Yasir Habib, Badar Munir
Objective: To compare the effects of closed and open techniques with its associated complications used for the management of distal femoral fracture in younger to older populations. Methodology: This was a case series study conducted in the Department of Orthopaedic Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad from Sept 2018- March 2019. A total of 66 adult patients were stratified according to treatment technique; closed technique group and open technique group with 33 patients in each group between age 18 - 65 years with fractured close distal 1/3rd shaft of femur distal femur fractures based on AO/OTA classification were included in the study. The Chi-square test was applied to contrast outcomes of closed and open technique and HSS score categories in both procedures. Results: The study findings showed that the mean age of the patient was slightly greater in the open technique group (41.5 + 23.5 years) compared to the closed technique (29.8 + 11.8 years). Most of the patients had type A femur fracture. The postoperative mean HSS knee score was 70.1 + 15.1 in the open technique group compared to 74.5 + 12.5 in the closed technique group with an insignificant difference between the two means (p<0.949). An insignificant difference was observed in postoperative infection, non-union, and implant failure between both groups. Conclusion: This study concluded that superior outcomes such as bony union without infection were achieved in patients with femur fractures treated with closed technique as compared to open technique, although the findings were statistically insignificant. Moreover, the functional outcome of the knee joint was also distinctly improved in the closed technique. Keywords: Distal femur fracture, retrograde intramedullary femoral nail, locking compression plate, complications
{"title":"Comparison of Early Outcome of the Close and Open Technique for the Treatment of Distal Femur Fractures","authors":"Fahad Nawaz Khan, Ali Shami, Muhammad Hanif, Yasir Farhan, Yasir Habib, Badar Munir","doi":"10.48036/apims.v19i1.558","DOIUrl":"https://doi.org/10.48036/apims.v19i1.558","url":null,"abstract":"Objective: To compare the effects of closed and open techniques with its associated complications used for the management of distal femoral fracture in younger to older populations.\u0000Methodology: This was a case series study conducted in the Department of Orthopaedic Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad from Sept 2018- March 2019. A total of 66 adult patients were stratified according to treatment technique; closed technique group and open technique group with 33 patients in each group between age 18 - 65 years with fractured close distal 1/3rd shaft of femur distal femur fractures based on AO/OTA classification were included in the study. The Chi-square test was applied to contrast outcomes of closed and open technique and HSS score categories in both procedures.\u0000Results: The study findings showed that the mean age of the patient was slightly greater in the open technique group (41.5 + 23.5 years) compared to the closed technique (29.8 + 11.8 years). Most of the patients had type A femur fracture. The postoperative mean HSS knee score was 70.1 + 15.1 in the open technique group compared to 74.5 + 12.5 in the closed technique group with an insignificant difference between the two means (p<0.949). An insignificant difference was observed in postoperative infection, non-union, and implant failure between both groups.\u0000Conclusion: This study concluded that superior outcomes such as bony union without infection were achieved in patients with femur fractures treated with closed technique as compared to open technique, although the findings were statistically insignificant. Moreover, the functional outcome of the knee joint was also distinctly improved in the closed technique.\u0000Keywords: Distal femur fracture, retrograde intramedullary femoral nail, locking compression plate, complications","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"731 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116067964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-19DOI: 10.48036/apims.v18i4.745
Maria Shahzad, Farrukh Iqbal, Naeem Malik, Mamoon Qadir, Saima Bashir, Muhammad ali
Objective: To determine the clinical outcomes of different two stent bifurcation techniques in the treatment of coronary bifurcation lesions, taking this as a challenge presented at the Pakistan Institute of Medical Sciences (PIMS), Islamabad. Methods: This descriptive cross-sectional was done at the Cardiology Department, PIMS, Islamabad, from September 2017 to February 2018. Individuals aged 20–60 years with true bifurcation lesions (> 50% stenosis diameter) in both parent/main vessel side branch ostia from lesions and with a diameter of >2.5 mm via visual approximation, silent ischemia, un-stable or stable angina, and denovo coronary bifurcation lesions of either gender were included. For PCI of these lesions, a variety of methods have been developed, frequently involving the use of numerous balloons and the implantation of two or more stents, including the crush stent technique, the Cullotte stent technique, and the kissing stent technique to allow maximum apposition to the vascular wall with efficient drug delivery in situation of drug-eluting stents. Patients were observed for clinical outcomes like cardiac death, stent thrombosis, nonprocedural MI, and during operation complications like edge dissection and side branch closure, recurrent myocardial infarction (MI), unstable angina, and MACE. All the information was collected via a study proforma, and the analysis was done using SPSS version 20. Results: The study included 100 cases, with an average age of 40 years and a range of 20 to 60 years. Out of all 58 (58%) males and 42 (42%) females. The T-Stent Technique was used in 30% of the study population, the Crush Stenting approach was used in 18% of the cases, the Culotte stenting approach was done in 22% of the cases, and kissing stenting approach was done in 30% of the study subjects. Amongst all the procedures, the Kissing Stent Technique was most successful in treating coronary bifurcating lesions 93.3%. As per procedures, complications were found to be statistically significant (p = 0.011). Conclusions: As per the study conclusion, kissing stent technique has been observed to be the most successful and least complicated technique in treating coronary bifurcating lesions.
目的:以伊斯兰堡巴基斯坦医学科学研究所(PIMS)提出的一项挑战为基础，确定不同双支架分岔技术治疗冠状动脉分岔病变的临床效果。方法:描述性横断面研究于2017年9月至2018年2月在伊斯兰堡PIMS心内科进行。年龄在20-60岁的患者，在病变的母/主血管侧分支口有真正的分叉病变(狭窄直径的50%)，通过视觉近似，>直径为2.5 mm，无症状缺血，不稳定或稳定型心绞痛，以及任何性别的冠状动脉分叉病变。对于这些病变的PCI，已经发展了多种方法，通常涉及使用大量球囊和植入两个或多个支架，包括粉碎支架技术、Cullotte支架技术和接吻支架技术，在药物洗脱支架的情况下，允许最大限度地靠近血管壁并有效地给药。观察患者的临床结果，如心源性死亡、支架血栓形成、非程序性心肌梗死，以及术中并发症，如边缘剥离和侧支关闭、复发性心肌梗死(MI)、不稳定型心绞痛和MACE。所有信息均通过研究形式表收集，并使用SPSS version 20进行分析。结果:纳入100例，平均年龄40岁，年龄范围20 ~ 60岁。在所有58名(58%)男性和42名(42%)女性中。30%的研究对象使用了t型支架技术，18%的研究对象使用了挤压支架，22%的研究对象使用了套索支架，30%的研究对象使用了接吻支架。在所有手术中，吻合器支架技术治疗冠状动脉分叉病变的成功率最高，为93.3%。术后并发症的发生率有统计学意义(p = 0.011)。结论:根据研究结论，吻合器支架技术是治疗冠状动脉分叉病变最成功、最简单的技术。
{"title":"Clinical Outcomes of Various Two Stent Bifurcation Techniques in Treating Coronary Bifurcation Lesions at Pakistan Institute of Medical Sciences (PIMS), Islamabad","authors":"Maria Shahzad, Farrukh Iqbal, Naeem Malik, Mamoon Qadir, Saima Bashir, Muhammad ali","doi":"10.48036/apims.v18i4.745","DOIUrl":"https://doi.org/10.48036/apims.v18i4.745","url":null,"abstract":"Objective: To determine the clinical outcomes of different two stent bifurcation techniques in the treatment of coronary bifurcation lesions, taking this as a challenge presented at the Pakistan Institute of Medical Sciences (PIMS), Islamabad.\u0000Methods: This descriptive cross-sectional was done at the Cardiology Department, PIMS, Islamabad, from September 2017 to February 2018. Individuals aged 20–60 years with true bifurcation lesions (> 50% stenosis diameter) in both parent/main vessel side branch ostia from lesions and with a diameter of >2.5 mm via visual approximation, silent ischemia, un-stable or stable angina, and denovo coronary bifurcation lesions of either gender were included. For PCI of these lesions, a variety of methods have been developed, frequently involving the use of numerous balloons and the implantation of two or more stents, including the crush stent technique, the Cullotte stent technique, and the kissing stent technique to allow maximum apposition to the vascular wall with efficient drug delivery in situation of drug-eluting stents. Patients were observed for clinical outcomes like cardiac death, stent thrombosis, nonprocedural MI, and during operation complications like edge dissection and side branch closure, recurrent myocardial infarction (MI), unstable angina, and MACE. All the information was collected via a study proforma, and the analysis was done using SPSS version 20.\u0000Results: The study included 100 cases, with an average age of 40 years and a range of 20 to 60 years. Out of all 58 (58%) males and 42 (42%) females. The T-Stent Technique was used in 30% of the study population, the Crush Stenting approach was used in 18% of the cases, the Culotte stenting approach was done in 22% of the cases, and kissing stenting approach was done in 30% of the study subjects. Amongst all the procedures, the Kissing Stent Technique was most successful in treating coronary bifurcating lesions 93.3%. As per procedures, complications were found to be statistically significant (p = 0.011).\u0000Conclusions: As per the study conclusion, kissing stent technique has been observed to be the most successful and least complicated technique in treating coronary bifurcating lesions.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124276204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-29DOI: 10.48036/apims.v18i4.728
Fahmina Nazir, Nida Armoghan Khan, M. Tahir, Hafiz Muhammad Jahan Zaib, Tahreem Mahmood, Amina Khalid
Objectives: To determine the incidence of sleep disturbances, including insomnia in healthcare professionals dealing with COVID-19 patients. Methodology: A cross-sectional study was conducted at inpatient infectious disease units, emergency department and ICU (for COVID-19 patients), at the Pakistan Institute of Medical Sciences (PIMS) from February 2022 to April 2022. All the individuals participating in the study were healthcare professionals. Insomnia Severity Index was used for the questionnaire. The scores of the surveyed subjects were calculated and the characteristic demographics of the subjects were analyzed. Results: An upward trend in the incidence of poor sleep quality was noted among the healthcare professionals who participated in this study. Out of 160 healthcare professionals, 93(58.1%) of the population was females, while 67(41.9%) were males. The majority of participants (p<0.05) were between the ages of 20 and 30 years, followed by 31 to 40 years and 41 to 50 years. A significant proportion of the population (p<0.05) belonged to the unmarried group, followed by the married, separated, and divorced with a percentage of 60.6, 36.2, 2.5 and 0.6%, respectively. Moreover, 84.4% (135/160) of healthcare professionals (p<0.05) had a previous history of sleep disorders. Insomnia Severity Index (ISI) score system was used to analyze the intensity of sleep disorders and insomnia in the affected persons and it was found that most of the participants were diagnosed with subthreshold insomnia (38.8%). Conclusion: The study elucidated that there was a significantly higher incidence of sleep disturbances and insomnia, in healthcare professionals working in Covid-19 care units.
{"title":"Sleep Disturbances in Healthcare Professionals During the Covid-19 Pandemic","authors":"Fahmina Nazir, Nida Armoghan Khan, M. Tahir, Hafiz Muhammad Jahan Zaib, Tahreem Mahmood, Amina Khalid","doi":"10.48036/apims.v18i4.728","DOIUrl":"https://doi.org/10.48036/apims.v18i4.728","url":null,"abstract":"Objectives: To determine the incidence of sleep disturbances, including insomnia in healthcare professionals dealing with COVID-19 patients.\u0000Methodology: A cross-sectional study was conducted at inpatient infectious disease units, emergency department and ICU (for COVID-19 patients), at the Pakistan Institute of Medical Sciences (PIMS) from February 2022 to April 2022. All the individuals participating in the study were healthcare professionals. Insomnia Severity Index was used for the questionnaire. The scores of the surveyed subjects were calculated and the characteristic demographics of the subjects were analyzed.\u0000Results: An upward trend in the incidence of poor sleep quality was noted among the healthcare professionals who participated in this study. Out of 160 healthcare professionals, 93(58.1%) of the population was females, while 67(41.9%) were males. The majority of participants (p<0.05) were between the ages of 20 and 30 years, followed by 31 to 40 years and 41 to 50 years. A significant proportion of the population (p<0.05) belonged to the unmarried group, followed by the married, separated, and divorced with a percentage of 60.6, 36.2, 2.5 and 0.6%, respectively. Moreover, 84.4% (135/160) of healthcare professionals (p<0.05) had a previous history of sleep disorders. Insomnia Severity Index (ISI) score system was used to analyze the intensity of sleep disorders and insomnia in the affected persons and it was found that most of the participants were diagnosed with subthreshold insomnia (38.8%).\u0000Conclusion: The study elucidated that there was a significantly higher incidence of sleep disturbances and insomnia, in healthcare professionals working in Covid-19 care units.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128953992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To assess the effect of giving toothbrushing storybooks along with verbal oral hygiene (OHI) instructions on plaque levels to schoolchildren. Methodology: This quasi-experimental study was conducted in a private school in Islamabad from October to November 2022. Children in Class V were selected as the Experimental Group I (Storybooks + OHI), while Class IV children were placed in the Control Group II (OHI alone). There were 20 students in each group. Plaque levels were compared at the baseline (before intervention) and after seven days. Toothbrushing practices were recorded at the baseline. Results: The mean age of the children was 9.6 + 1.08 years. A total of 16 (40%) boys and 24 (60%) girls were included in the study. Children in Group II had significantly better self-reported toothbrushing practices with 16 (80%) children brushing twice a day, as compared to 10 (50%) children from Group I (p = 0.041). There was no difference in the reduction in plaque scores between group I (0.14 + 0.21) and group II (0.08 + 0.21; p = 0.382). Conclusion: Giving story books to children is not an effective intervention to improve the oral hygiene status of children, as compared to oral hygiene instructions alone.
{"title":"Evaluating The Impact of Giving Tooth Brushing Story Books on The Dental Plaque Levels of Children; A Parallel Arm Non-Randomized Clinical Trial","authors":"Miraat Anser, Sibtul Hassan, Bassam Amjad, Shaban Malik, Musa Cheema, Zainab Memon","doi":"10.48036/apims.v18i4.752","DOIUrl":"https://doi.org/10.48036/apims.v18i4.752","url":null,"abstract":"Objective: To assess the effect of giving toothbrushing storybooks along with verbal oral hygiene (OHI) instructions on plaque levels to schoolchildren. \u0000Methodology: This quasi-experimental study was conducted in a private school in Islamabad from October to November 2022. Children in Class V were selected as the Experimental Group I (Storybooks + OHI), while Class IV children were placed in the Control Group II (OHI alone). There were 20 students in each group. Plaque levels were compared at the baseline (before intervention) and after seven days. Toothbrushing practices were recorded at the baseline. \u0000Results: The mean age of the children was 9.6 + 1.08 years. A total of 16 (40%) boys and 24 (60%) girls were included in the study. Children in Group II had significantly better self-reported toothbrushing practices with 16 (80%) children brushing twice a day, as compared to 10 (50%) children from Group I (p = 0.041). There was no difference in the reduction in plaque scores between group I (0.14 + 0.21) and group II (0.08 + 0.21; p = 0.382). \u0000Conclusion: Giving story books to children is not an effective intervention to improve the oral hygiene status of children, as compared to oral hygiene instructions alone.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"33 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114043022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim was to assess the safety of Remdesivir in Patients with Acute and Chronic Kidney DiseaseMethodology: Quasi-experimental study was conducted at the Pak Emirates Military Hospital Rawalpindi from March 2021 to April 2022. A sample was collected through a non-random sampling method, recruiting those who were diagnosed with pneumonia caused by the COVID-19 virus. A total of 56 patients with acute or chronic kidney disease were the participants of our study. The inclusion criterion was patient with positive COVID PCR 7-10 days prior to the commencement of the study. Patients admitted to the hospital nephrology ward with any stage of AKI were also considered for inclusion in the study. However, patients under the age of 18 and those who refused to participate were excluded.Results: The serum creatinine value were 125.15 ± 8.61 u/L and 126.44 ± 5.72 micromoles/L before and after Remdesivir use respectively. The serum ALT changed from 34.55 ± 2.69 u/L to 33.26 ± 1.85 u/L while Serum AST changed from 54.69 ± 4.04 u/L to 55.42 ± 3.09 u/L in patients with renal diseases when treated with Remdesivir for COVID-19.Conclusion: This study concluded that Remdesivir had no statistically significant effect on serum creatinine, AST and ALT. It also showed that these values showed and above normal pattern from baseline before and after the administration of Remdesivir when given in participants of the study undergoing COVID treatment with AKI or CKD.
{"title":"Safety of Remdesivir in Covid Patients with Acute or Chronic Kidney Disease","authors":"Haseeb Nasir, Khalid Mehmood Raja, Shahzeb Satti, Roshaan Tahir, Maryam Zafar, Ahmed Tanveer","doi":"10.48036/apims.v18i4.668","DOIUrl":"https://doi.org/10.48036/apims.v18i4.668","url":null,"abstract":"Objective: The aim was to assess the safety of Remdesivir in Patients with Acute and Chronic Kidney DiseaseMethodology: Quasi-experimental study was conducted at the Pak Emirates Military Hospital Rawalpindi from March 2021 to April 2022. A sample was collected through a non-random sampling method, recruiting those who were diagnosed with pneumonia caused by the COVID-19 virus. A total of 56 patients with acute or chronic kidney disease were the participants of our study. The inclusion criterion was patient with positive COVID PCR 7-10 days prior to the commencement of the study. Patients admitted to the hospital nephrology ward with any stage of AKI were also considered for inclusion in the study. However, patients under the age of 18 and those who refused to participate were excluded.Results: The serum creatinine value were 125.15 ± 8.61 u/L and 126.44 ± 5.72 micromoles/L before and after Remdesivir use respectively. The serum ALT changed from 34.55 ± 2.69 u/L to 33.26 ± 1.85 u/L while Serum AST changed from 54.69 ± 4.04 u/L to 55.42 ± 3.09 u/L in patients with renal diseases when treated with Remdesivir for COVID-19.Conclusion: This study concluded that Remdesivir had no statistically significant effect on serum creatinine, AST and ALT. It also showed that these values showed and above normal pattern from baseline before and after the administration of Remdesivir when given in participants of the study undergoing COVID treatment with AKI or CKD.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"05 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128242075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The objective of the study is to compare gain in bone height and post-operative complications e with direct and indirect sinus lift procedure. Methods: This prospective clinical study was conducted at the department of Science of Dental Materials, University Medical and Dental college Faisalabad, in a period of one year from November 2021 to November 2022. For patients in the 20-50 years age range either gender with maxillary posterior edentulous regions but with a low sinus and deficient alveolar ridge, implant retained prostheses would be a viable option. Results: Results showed that pain and gingival inflammation resolved at 1st week postoperatively. These two parameters frequency was higher in patients with indirect method as compared to patients who were treated with direct method. Swelling was also settled in both treatment groups after 1st week postoperatively. However, frequency of swelling was higher in indirect method as that of direct method but the difference was not statistically significant. There is significant change in bone height postoperatively in both treatment groups. But gain in mean bone height was significantly higher in patients treated with direct approach. Conclusion: This study did not find a significant difference between direct versus indirect sinus lift procedures in terms of swelling, inflammation, and pain following surgery. Indirect sinus lifts, however, result in a significantly lower bone height gain than direct sinus lifts. Key Words: Edentulism, Sinus lift procedures, Direct, Indirect, Bone height, Sinus surgery.
{"title":"Comparison of Implant Success Rate Between Direct And Indirect Sinus Lift Procedure","authors":"Tahmeena Atiq, Sarosh Iqbal, Waqas Rashid, Qurat ul ain, Iqra Asghar, Tariq Javed","doi":"10.48036/apims.v18i4.761","DOIUrl":"https://doi.org/10.48036/apims.v18i4.761","url":null,"abstract":"Objective: The objective of the study is to compare gain in bone height and post-operative complications e with direct and indirect sinus lift procedure.\u0000Methods: This prospective clinical study was conducted at the department of Science of Dental Materials, University Medical and Dental college Faisalabad, in a period of one year from November 2021 to November 2022. For patients in the 20-50 years age range either gender with maxillary posterior edentulous regions but with a low sinus and deficient alveolar ridge, implant retained prostheses would be a viable option.\u0000Results: Results showed that pain and gingival inflammation resolved at 1st week postoperatively. These two parameters frequency was higher in patients with indirect method as compared to patients who were treated with direct method. Swelling was also settled in both treatment groups after 1st week postoperatively. However, frequency of swelling was higher in indirect method as that of direct method but the difference was not statistically significant. There is significant change in bone height postoperatively in both treatment groups. But gain in mean bone height was significantly higher in patients treated with direct approach.\u0000Conclusion: This study did not find a significant difference between direct versus indirect sinus lift procedures in terms of swelling, inflammation, and pain following surgery. Indirect sinus lifts, however, result in a significantly lower bone height gain than direct sinus lifts. \u0000Key Words: Edentulism, Sinus lift procedures, Direct, Indirect, Bone height, Sinus surgery.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133281469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-29DOI: 10.48036/apims.v18i4.675
Muhammad Niaz khan, Samiullah khan, Sadullah Shah, Shahab Saidullah, Muhammad Nadeem Khan, Nasir Ali
Objective: To determine the angiographic severity of CAD in diabetic versus non-diabetic patients undergoing primary PCI for STEMI. Methodology: This cross-sectional observational study was carried out in the Cardiology unit of Hayatabad Medical Complex Peshawar from January, 2021 to August 2021. All patients undergoing primary PCI for STEMI at cardiology unit of HMC were included in the study after a thorough history, examination and informed consent. Patients were divided into two categories on the basis of diabetes status. Furthermore, patients were also classified on the basis of number of vessels with significant coronary stenosis. Continuous variables were described as means and standard deviations whereas categorical variables were described as frequencies and percentages. Chi-square test was applied to determine the significance of categorical variables. Results: A total of 68 patients with a mean age of 52±4.5 years were included in the study. Of these, 49 were males and 27 patients had diabetes. In the diabetes group, 20 patients had a history of anterior wall MI whereas 19 patients had history of anterior wall MI in the non-diabetes group. Similarly, 15 patients in the diabetes group and 11 patients in the non-diabetes group had inferior wall MI (p: 0.095). Furthermore, the number of patients who had TVCAD, DVCAD and SVCAD in the diabetic group was 15, 5 and 7 compared to 7, 15 and 19 in the non-diabetic group respectively (X2=11.039, p:<0.01). Two patients in the diabetes group had stent thrombosis whereas only 1 patient had stent thrombosis in the non-diabetes group. One patient died in the cath lab in the diabetic group whereas there was no mortality in the non-diabetic group. Conclusion: Diabetic patients presenting with STEMI is having more severe and extensive CAD during primary PCI as compared to non diabetic patients.
目的:比较糖尿病患者与非糖尿病患者行原发性STEMI PCI时冠心病的血管造影严重程度。方法:这项横断面观察性研究于2021年1月至2021年8月在白沙瓦Hayatabad医疗中心心脏病科进行。所有在HMC心内科接受STEMI初级PCI治疗的患者在经过全面的病史、检查和知情同意后被纳入研究。根据糖尿病状况将患者分为两类。此外，还根据冠状动脉明显狭窄的血管数量对患者进行分类。连续变量被描述为均值和标准差，而分类变量被描述为频率和百分比。采用卡方检验确定分类变量的显著性。结果:共纳入68例患者，平均年龄52±4.5岁。其中男性49例，糖尿病患者27例。糖尿病组20例患者有前壁心肌梗死史，非糖尿病组19例患者有前壁心肌梗死史。同样，糖尿病组15例，非糖尿病组11例发生下壁心肌梗死(p: 0.095)。糖尿病组TVCAD、DVCAD、SVCAD患者分别为15例、5例、7例，非糖尿病组分别为7例、15例、19例(X2=11.039, p <0.01)。2例糖尿病组患者有支架血栓形成，而非糖尿病组只有1例患者有支架血栓形成。糖尿病组有一名患者在导管室死亡，而非糖尿病组没有死亡。结论:与非糖尿病患者相比，伴有STEMI的糖尿病患者在初次PCI中出现更严重和更广泛的CAD。
{"title":"Angiographic Severity of CAD in Diabetic Versus Non-Diabetic Patients Presenting with STEMI","authors":"Muhammad Niaz khan, Samiullah khan, Sadullah Shah, Shahab Saidullah, Muhammad Nadeem Khan, Nasir Ali","doi":"10.48036/apims.v18i4.675","DOIUrl":"https://doi.org/10.48036/apims.v18i4.675","url":null,"abstract":"Objective: To determine the angiographic severity of CAD in diabetic versus non-diabetic patients undergoing primary PCI for STEMI.\u0000Methodology: This cross-sectional observational study was carried out in the Cardiology unit of Hayatabad Medical Complex Peshawar from January, 2021 to August 2021. All patients undergoing primary PCI for STEMI at cardiology unit of HMC were included in the study after a thorough history, examination and informed consent. Patients were divided into two categories on the basis of diabetes status. Furthermore, patients were also classified on the basis of number of vessels with significant coronary stenosis. Continuous variables were described as means and standard deviations whereas categorical variables were described as frequencies and percentages. Chi-square test was applied to determine the significance of categorical variables.\u0000Results: A total of 68 patients with a mean age of 52±4.5 years were included in the study. Of these, 49 were males and 27 patients had diabetes. In the diabetes group, 20 patients had a history of anterior wall MI whereas 19 patients had history of anterior wall MI in the non-diabetes group. Similarly, 15 patients in the diabetes group and 11 patients in the non-diabetes group had inferior wall MI (p: 0.095). Furthermore, the number of patients who had TVCAD, DVCAD and SVCAD in the diabetic group was 15, 5 and 7 compared to 7, 15 and 19 in the non-diabetic group respectively (X2=11.039, p:<0.01). Two patients in the diabetes group had stent thrombosis whereas only 1 patient had stent thrombosis in the non-diabetes group. One patient died in the cath lab in the diabetic group whereas there was no mortality in the non-diabetic group.\u0000Conclusion: Diabetic patients presenting with STEMI is having more severe and extensive CAD during primary PCI as compared to non diabetic patients.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114384517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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