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THE RELATIONSHIP BETWEEN PLATELET COUNT, PDW, PCT, AND MPV WITH VISUAL FIELD DEFECT IN PRIMARY OPEN ANGLE GLAUCOMA 原发性开角型青光眼血小板计数、pdw、pct、MPV与视野缺损的关系
Pub Date : 2022-09-01 DOI: 10.32734/sumej.v5i3.9065
Marini Yusufina Lubis
Abstract.  Glaucoma is a multifactorial disease and the second leading cause of irreversible blindness worldwide, and incidence of open-angle glaucoma more frequent, including in Indonesia. The etiology is still unclear, but the risk factors are the immune system and increased systemic microvascular abnormalities affected by platelets. Objective. The purpose of this study was to determine the relationship between platelet parameters and visual field defect in POAG. Methods. This research is an analytic study with a case control design. Respondents are 30 POAG patients and 30 normal subjects as a control in Universitas Sumatera Utara Hospital and Satellite Hospital from August to December 2021. Venous blood samples were taken as much as 3 cc to assess platelet parameters, then analyzed in the clinical laboratory. Each group was examined with Humphrey's Perimetry which was further classified based on Hodapp Anderson Parrish criteria. Results. Most subjects in the POAG group are male, 53.3%. In POAG group the mean values of  platelet count 267.28 103/μL, PDW 11.41 fL, PCT 0.25%, and MPV 9.49 fL. Conclusion. There was an increase in PDW values in advanced POAG patients, but no significant differences were found in visual field defect between the two groups.  
抽象的。青光眼是一种多因素疾病,是全世界不可逆失明的第二大原因,开角型青光眼的发病率更高,包括在印度尼西亚。病因尚不清楚,但危险因素是免疫系统和血小板影响的系统性微血管异常增加。目标。本研究旨在探讨血小板参数与POAG患者视野缺损的关系。方法。本研究为个案对照分析研究。调查对象为2021年8月至12月在苏门答腊北方大学医院和附属医院的30名POAG患者和30名正常人作为对照。静脉血最多取3cc以评估血小板参数,然后在临床实验室进行分析。每组采用Humphrey's Perimetry检查,并根据Hodapp Anderson Parrish标准进一步分类。结果。POAG组以男性居多,占53.3%。POAG组血小板计数平均值267.28 103/μL, PDW平均值11.41 fL, PCT平均值0.25%,MPV平均值9.49 fL。晚期POAG患者的PDW值升高,但视野缺损两组间无显著差异。
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引用次数: 0
The Relationship Between Anxiety Level with the Onset of Acne Vulgaris in Medical Faculty of Universitas Sumatera Utara 2016 – 2018 2016 - 2018年苏门答腊大学医学院焦虑水平与寻常性痤疮发病的关系
Pub Date : 2022-05-01 DOI: 10.32734/sumej.v5i2.7890
Vanny Salsabila, C. Hazlianda
Acne vulgaris (AV) is a chronic inflammation of the follicle pilosebaceous induced by Propionibacterium acnes. Anxious circumstances increase the androgen hormones. This increases the production of sebum and the proliferation then activates Propionibacterium acnes, resulting in AV. To find out the relationship between levels of anxiety and the onset of AV to the Faculty of Medicine, Universitas Sumatera Utara (FK USU) 2016 – 2018 conducted observational research with cross sectional design. This research samples as many as 66 students of FK USU Group 2016 – 2018 and using stratified random sampling method. The result of anxiety level of FK USU students indicates that there are mild anxiety (92.4%) moderate anxiety (6.1%) and severe anxiety (1.5%). The AV event of FK USU students indicates that there are mild acne (51.5%) moderate acne (40.9%) severe acne (6.1%) and normal results (1.5%). With the chi square test there is a significant link between the level of anxiety and the onset of the vulgaris (p = 0.026). There is a significant relationship between the levels of anxiety with the onset of AV on student of FK USU 2016-2018.
寻常痤疮(AV)是由痤疮丙酸杆菌引起的毛囊皮脂腺慢性炎症。焦虑的环境会增加雄激素。这增加了皮脂的产生和增殖,然后激活痤疮丙酸杆菌,导致AV。为了找出焦虑水平与AV发病之间的关系,苏门答腊北部大学医学院(FK USU) 2016 - 2018年进行了横断面设计的观察性研究。本研究采用分层随机抽样的方法,对2016 - 2018年FK USU集团66名学生进行了抽样调查。南大FK学生的焦虑水平结果显示:轻度焦虑(92.4%)、中度焦虑(6.1%)和重度焦虑(1.5%)。FK USU学生AV事件显示:轻度痤疮(51.5%)、中度痤疮(40.9%)、重度痤疮(6.1%)、正常痤疮(1.5%)。通过卡方检验,焦虑水平与寻常性发作之间存在显著联系(p = 0.026)。USU 2016-2018级学生焦虑水平与AV发病有显著相关。
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引用次数: 0
Relationship of HbA1c to Diabetic Retinopathy in Type 2 DM Patients at Haji Adam Malik General Hospital 2017-2018 2017-2018年哈吉亚当马利克总医院2型糖尿病患者HbA1c与糖尿病视网膜病变的关系
Pub Date : 2021-09-07 DOI: 10.32734/sumej.v3i3.3626
Yuni Silalahi, Ricke Loesnihari
Diabetic retinopathy is a microvascular complication of diabetes mellitus. This complication can occur due to hyperglycemia that occurs in blood vessels for a long period of time. To determine whether there is a relationship between HbA1c levels on the incidence of diabetic retinopathy on pationts with type 2 diabetes mellitus in Haji Adam Malik General Hospital Medan period of 2017 until 2018. This research is an analitical study with retrospective method (case control) and conducted at the General Hospital of Haji Adam Malik Medan. Data collection was performed on medical records of diabetic retinopathy patients at Haji Adam Malik General Hospital Medan in the period January 2017 to December 2018. Data were collected by using medial records of patients with simple random sampling technique with a total sample is 46 samples, 23 samples of diabetic retinopathy, and 23 samples that were not diabetic retinopathy. The results of this study indicate that of 23 diabetic retinopathy samples, 2 of them had controlled HbA1c and the other 21 are not controlled. As well as of the 23 samples were not diabetic retinopathy, 5 of them had HbA1c controlled HbA1c and 18 were uncontrolled. The result of the analysis with chi square test showed no relationship between HbA1c levels to the incidemce of diabetic retinopathy in Type 2 DM patients with a p value of 0,06. From this study it was found that there was no relationship between HbA1c levels and the incidence of diabetic retinopathy for Haji Adam Malik General Hospital in the 2017-2018 period.
糖尿病视网膜病变是糖尿病的微血管并发症。这种并发症可能是由于长时间发生在血管中的高血糖引起的。目的探讨2017 - 2018年哈吉亚当马利克综合医院2型糖尿病患者糖尿病视网膜病变发生率与HbA1c水平之间是否存在关系。本研究采用回顾性分析方法(病例对照),在哈吉·亚当·马利克·梅丹总医院进行。对2017年1月至2018年12月期间棉兰哈吉亚当马利克综合医院糖尿病视网膜病变患者的医疗记录进行数据收集。采用简单随机抽样技术,采用患者病历资料收集,共46例,其中糖尿病视网膜病变23例,非糖尿病视网膜病变23例。本研究结果显示,23例糖尿病视网膜病变患者HbA1c控制2例,未控制21例。23例非糖尿病视网膜病变患者中,5例HbA1c控制,18例HbA1c未控制。卡方检验分析结果显示,HbA1c水平与2型DM患者糖尿病视网膜病变发生率无相关性,p值为0.06。本研究发现哈吉亚当马利克综合医院2017-2018年期间HbA1c水平与糖尿病视网膜病变发生率无相关性。
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引用次数: 0
Serum 25-Hydroxyvitamin D Levels as a Predictive Factor for Allergic Rhinitis 血清25-羟基维生素D水平作为变应性鼻炎的预测因素
Pub Date : 2021-08-20 DOI: 10.32734/sumej.v4i3.7626
Lia Restimulia, D. Munir
Introduction: Allergy and 25-Hydroxyvitamin D deficiency were mentioned to be correlated. Still, there was limited number of studies in determining serum 25-Hydroxyvitamin D levels as a predictive factor, particularly in allergic rhinitis (AR). This study has never been implemented in Indonesia which the main objective was to explore this topic. Methods: Consecutive sampling was used in recruiting the fifteen subjects. Serum 25-Hydroxyvitamin D levels were quantified using electrochemiluminescence immunoassay (ECLIA) method while the total nasal symptom scores were acquired by enumerate all nasal symptoms. Data of serum vitamin D levels and TNSS were analysed statistically.Results: Based on our previous study, the predictive value was illustrated from linier regresion = 10,230 – 0,281 (vitamin D), with negative moderate correlation (r = -0,613). This result can be comparable for someone with vitamin D level of 5.66 ng/mL that could predicted as 8.64 nasal score. Conclusion: 25-Hydroxyvitamin D could be a predictive factor for allergic rhinitis with negative moderate correlation. Hence, in the future research needs to be implemented.
引言:过敏与25-羟基维生素D缺乏有相关性。然而,确定血清25-羟基维生素D水平作为预测因素的研究数量有限,特别是在过敏性鼻炎(AR)中。这项研究从未在印度尼西亚实施,其主要目的是探讨这一主题。方法:采用连续抽样的方法招募15名受试者。采用电化学发光免疫分析法(ECLIA)定量测定血清25-羟基维生素D水平,通过列举所有鼻症状获得总鼻症状评分。对血清维生素D水平和TNSS数据进行统计学分析。结果:在我们前期研究的基础上,线性回归= 10,230 ~ 0,281(维生素D),呈负中相关(r = -0,613)。这一结果可以与维生素D水平为5.66 ng/mL的人相比较,可以预测鼻腔评分为8.64。结论:25-羟基维生素D可能是变应性鼻炎的预测因素,并呈负中相关。因此,在未来的研究需要实施。
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引用次数: 0
Correlation of Platelet-Lymphocyte Ratio (PLR) and Contrast-Induced Nephropathy (CIN) in Patients with ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary Percutaneous Coronary Intervention (PCI) st段抬高型心肌梗死(STEMI)行首次经皮冠状动脉介入治疗(PCI)患者血小板淋巴细胞比(PLR)与造影剂肾病(CIN)的相关性
Pub Date : 2021-04-20 DOI: 10.32734/SUMEJ.V4I2.5836
Steven Winardi, A. Sitepu
Acute Coronary Syndrome (ACS) is a series of clinical disorders caused by acute ischemic heart disease. The clinical spectrum of ACS is unstable angina pectoris (UAP), non  ST segment elevation myocardial infarction (NSTEMI) and ST segment elevation myocardial infarction (STEMI). Inflammation occurs from the early stages of atheroma formation to plaque rupture and thrombosis. Thrombocytosis and lymphopenia are associated with the degree of systemic inflammation and the platelet lymphocyte ratio (PLR) is a new marker involving both hematological indices. ST segment elevation myocardial infarction is a type of acute myocardial infarction with high mortality. Management of STEMI patients is carried out with reperfusion therapy consisting of primary percutaneous coronary intervention (PCI) and fibrinolytics. Contrast-induced nephropathy is a serious complication of angiograph procedures that results from administration of contrast media.
急性冠脉综合征(ACS)是由急性缺血性心脏病引起的一系列临床疾病。ACS临床表现为不稳定型心绞痛(UAP)、非ST段抬高型心肌梗死(NSTEMI)和ST段抬高型心肌梗死(STEMI)。炎症发生在动脉粥样硬化形成的早期阶段,直至斑块破裂和血栓形成。血小板增多和淋巴细胞减少与全身炎症程度有关,血小板淋巴细胞比(PLR)是一个涉及两项血液学指标的新指标。ST段抬高型心肌梗死是一种病死率较高的急性心肌梗死。STEMI患者的治疗采用再灌注治疗,包括初级经皮冠状动脉介入治疗(PCI)和纤溶酶治疗。造影剂肾病是血管造影术的严重并发症,由造影剂引起。
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引用次数: 0
The Relationship Between Exclusive Breastfeeding And Diarrhea In Children Aged 6-24 Months At Aek Parombunan Public Health Center, South Sibolga 2019 纯母乳喂养与6-24月龄儿童腹泻的关系在南西博尔加Aek Parombunan公共卫生中心,2019
Pub Date : 2021-04-20 DOI: 10.32734/SUMEJ.V4I2.5792
Tamara Lubis, D. Anggraini
Diarrhea is a symptom of infection in the intestinal tract with the second death rate in the world in children under five years of age. Risk factors for the incidence of diarrhea in children under five are host factors that increase susceptibility to diarrhea, not giving exclusive breastfeeding (ASI), not giving breastfeeding for 2 years, malnutrition, measles and immunodeficiency. Breastfeeding (ASI) contains the best nutrients that match the needs of the baby and exclusive breastfeeding is carried out from birth to the first six months without any additional food or drink. Several studies have shown that the immunity content of breastfeeding is able to coat the gastrointestinal mucosa and protect the digestive tract from incoming pathogens. The aim of this study is to find out the relationship between exclusive breastfeeding and the incidence of diarrhea in children aged 6-24 months at Puskesmas Aek Parombunan, Sibolga Selatan in 2019. The research design used was observational analytic cross-sectional with the criteria for the research sample of toddlers aged 6-24 months. The sampling technique in this study used total sampling. The research instrument was a medical record and data analysis used the chi-square test. Based on the results of the study, there was a relation between exclusive breastfeeding and the incidence of diarrhea.
腹泻是肠道感染的一种症状,5岁以下儿童的死亡率居世界第二位。5岁以下儿童腹泻发病率的危险因素有:增加腹泻易感性的宿主因素、未纯母乳喂养(ASI)、未母乳喂养2年、营养不良、麻疹和免疫缺陷。母乳喂养(ASI)包含与婴儿需要相匹配的最佳营养,纯母乳喂养从出生到头六个月,没有任何额外的食物或饮料。几项研究表明,母乳喂养的免疫成分能够覆盖胃肠道粘膜,保护消化道免受传入病原体的侵害。本研究旨在了解2019年Sibolga Selatan地区Puskesmas Aek Parombunan地区6-24月龄儿童纯母乳喂养与腹泻发生率之间的关系。研究设计采用观察分析横断面法,研究样本为6-24月龄幼儿。本研究的抽样技术采用全抽样。研究工具为病历,数据分析采用卡方检验。根据研究结果,纯母乳喂养与腹泻发生率之间存在关联。
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引用次数: 0
Descent of Fetal Head into The Pelvic Inlet in Primigravida: Systematic Review 初生动物胎儿头向骨盆入口的下降:系统回顾
Pub Date : 2021-04-20 DOI: 10.32734/SUMEJ.V4I2.5845
Imanuel Sihotang, M. Sitepu, M. Rusda
 Background: Skilled care before, during and after delivery can save the lives of women and newborns. Antenatal care is useful for detecting problems in pregnancy and childbirth, as well as preparing for labor. It is estimated that labor will begin 2-3 weeks after the entry of the fetal head on pelvic inlet. Objective: This study was conducted to determine the prevalence of descending of the fetal head at the pelvic inlet in the primigravida of 34-36 weeks of gestation. Methods: This study uses a systematic review study method with the data used are the results of research that have been circulating in the world. Results: In Weekes and Flynn's (1975) study, the entry of the fetal head into the pelvic cavity and having passed the pelvic inlet with a sample of 422 primigravidas, the prevalence was 34 weeks (2%), 35 weeks (1%). Of the three studies analyzed at 36 weeks' gestation, a prevalence was 4.22%.
背景:分娩前、分娩中和分娩后的熟练护理可以挽救妇女和新生儿的生命。产前保健有助于发现怀孕和分娩中的问题,并为分娩做准备。据估计,分娩将在胎儿头部进入骨盆入口后2-3周开始。目的:研究孕34 ~ 36周初产妇骨盆入口胎头下降的发生率。方法:本研究采用系统综述研究方法,所用数据均为国际上已有的研究成果。结果:在Weekes和Flynn(1975)的研究中,422例原孕鼠的样本中,胎头进入盆腔并通过盆腔入口,患病率为34周(2%),35周(1%)。在妊娠36周分析的三项研究中,患病率为4.22%。
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引用次数: 0
Correlation of Stress Levels and the Incidence of Pityriasis Sicca in Final Year Students of the Faculty of Medicine, Universitas Sumatera Utara Class of 2017 北苏门答腊大学医学院2017届毕业班学生压力水平与糠疹发病率的相关性
Pub Date : 2021-04-20 DOI: 10.32734/SUMEJ.V4I2.5775
Marlina, Riana Miranda Sinaga
Background: Pityriasis sicca is a non-inflammatory skin disorder. The symptoms such as white or gray scales that accumulate on the surface of the scalp or in a localized place, peels easily and usually with itching. There are three main factors that cause Pityriasis sicca. Stress stimulates the body to increase sebum production in the sebaceous glands. Objective: To know the correlation between stress levels and incidence of Pityriasis sicca in the final year students of the Faculty of Medicine, Universitas Sumatera Utara class of 2017. Methods: This was an analytical study with a cross-sectional design, started from  July 2020 until October 2020. Sampling was carried out using a total sampling technique. The data were obtained using univariate and bivariate statistical analysis. Results: Univariate analysis showed 102 respondents were at a normal stress level (40.3%) and there were 105 respondents (41.5%) who suffered from Pityriasis sicca, total samples were 253 respondents. From the bivariate analysis, it was found that there is a significant correlation between stress levels and the incidence of Pityriasis sicca. Conclusion: There is correlation between stress levels and the incidence of Pityriasis sicca in class 2017 students of the Faculty of Medicine, Universitas Sumatera Utara.
背景:镰状糠疹是一种非炎症性皮肤病。在头皮表面或局部积聚的白色或灰色鳞屑等症状很容易脱落,通常伴有瘙痒。有三个主要因素导致糠疹病。压力刺激身体增加皮脂腺的皮脂分泌。目的:了解苏门答腊大学医学院2017级毕业班学生压力水平与糠疹发病率的相关性。方法:这是一项横断面设计的分析性研究,从2020年7月开始到2020年10月。采用全采样技术进行采样。数据采用单变量和双变量统计分析。结果:单因素分析显示,102名被调查者应激水平正常(40.3%),105名被调查者患有镰状糠疹(41.5%),共253名被调查者。从双变量分析中发现,应激水平与该病的发病率之间存在显著的相关性。结论:苏门答腊大学医学院2017级学生压力水平与糠疹发病率存在相关性。
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引用次数: 2
Charasteristics of COVID-19 Patients Treated At Santa Elisabeth Medan Hospital 2020 圣伊丽莎白棉兰医院新冠肺炎患者治疗特点2020
Pub Date : 2021-01-20 DOI: 10.32734/sumej.v4i1.5958
Nency Triputri, Noni Novisari Soeroso
Corona Virus Disease (COVID-19) is a disease caused by a new type of coronavirus (SARS-CoV-2). This virus was first discovered in Wuhan, China for the first time and has infected 90,308 people as of March 2, 2020. Infection is transmitted by large droplets or droplets within 1 - 2 m, which are generated during coughing and sneezing by symptomatic patients and people without symptoms. This infection is acquired by inhaling these droplets or touching a contaminated surface and then touching the nose, mouth and eyes.  To see the characteristics of COVID-19 patients who are treated at the Santa Elisabeth Hospital Medan in 2020.  Type of research is a descriptive study with a cross-sectional study design with a retrospective approach using total sampling technique. This type of research data is secondary data obtained from the medical record data of positive COVID-19 patients confirmed to be hospitalized in several Medan city hospitals in 2020.Of the 230 study samples, 147 confirmed positive COVID-19 patients were found, dominated by the age range 46-55 years. The sex most common is male. The most common clinical symptoms are respiratory disorders such as coughing, shortness of breath and fever.The number of confirmed positive patients at the hospital. Santa Elisabeth in March to October 2020 is 147 people (51.1%).
冠状病毒病(COVID-19)是一种由新型冠状病毒(SARS-CoV-2)引起的疾病。该病毒首次在中国武汉发现,截至2020年3月2日,已有90308人感染。有症状的患者和无症状的人在咳嗽、打喷嚏时产生的大飞沫或1 - 2米内的飞沫传播感染。这种感染是通过吸入这些飞沫或接触受污染的表面,然后接触鼻子、嘴巴和眼睛而获得的。了解2020年在棉兰圣伊丽莎白医院接受治疗的COVID-19患者的特征。研究类型为描述性研究,采用横断面研究设计,采用回顾性方法,采用总抽样技术。此类研究数据为二级数据,来自2020年棉兰市多家医院确诊住院的COVID-19阳性患者的病历数据。在230个研究样本中,发现147例COVID-19确诊阳性患者,主要年龄在46-55岁之间。最常见的性别是男性。最常见的临床症状是呼吸系统疾病,如咳嗽、呼吸急促和发烧。医院确诊阳性患者的数量。2020年3月至10月的圣伊丽莎白是147人(51.1%)。
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引用次数: 0
Urinary Tract Infection Bacterial at RSUP H. Adam Malik Medan in 2019: an Overview Study 2019年棉兰RSUP H. Adam Malik尿路感染细菌综述研究
Pub Date : 2021-01-20 DOI: 10.32734/sumej.v4i1.5849
Teguh Firdaus, Rina Yunita
Urinary Tract Infection (UTI) is the second-largest infection after respiratory tract infection (WHO, 2013). The prevalence of UTI in Indonesia is relatively high. UTI originated from the invasion and proliferation of microorganisms into the urinary tract in meaningful quantities. Gram-negative bacteria are mostly the cause of UTI including E. coli, Klebsiella sp, Enterobacter sp, and Proteus sp. Patients with UTI with inadequate treatment can experience complications e.g., acute renal failure and urosepsis. This study aims to find out the profile of bacteria that cause UTI at RSUP H. Adam Malik Medan in 2019. This descriptive study is using a non-analytical retrospective approach conducted to secondary data from urinary culture examination at RSUP H. Adam Malik Medan. Data were analyzed using the SPSS 24.  Gram-negative bacteria results of 72.7% with E. coli postulated as the most common etiology (33,3%) and gram-positive bacteria results of 27.3%, dominated by Enterococcus faecalis (16.3%). The sensitivity study exhibited various results e.g., 100%, 98.2%, and 97.0% in E. coli for Tigecycline, Meropenem, and Amikacin respectively. Enterococcus faecalis also posed a similar results regarding its sensitivity result to different antibiotics. Gram-negative bacteria are the most common bacterial etiology of UTI, specifically E. coli with comparable sensitivity results
尿路感染是仅次于呼吸道感染的第二大感染(世卫组织,2013年)。印度尼西亚尿路感染的流行率相对较高。尿路感染起源于微生物大量侵入和增殖进入尿路。革兰氏阴性菌是引起尿路感染的主要原因,包括大肠杆菌、克雷伯氏杆菌、肠杆菌和变形杆菌等。尿路感染患者如果治疗不当,可能出现急性肾功能衰竭和尿脓毒症等并发症。这项研究旨在找出2019年在RSUP H. Adam Malik Medan引起尿路感染的细菌概况。本描述性研究采用非分析性回顾性方法,对RSUP H. Adam Malik Medan泌尿培养检查的次要数据进行分析。数据采用SPSS 24进行分析。革兰氏阴性菌占72.7%,其中大肠杆菌为最常见的病原菌(33.3%);革兰氏阳性菌占27.3%,以粪肠球菌为主(16.3%)。对替加环素、美罗培南和阿米卡星的敏感性研究显示出不同的结果,如大肠杆菌对替加环素、美罗培南和阿米卡星的敏感性分别为100%、98.2%和97.0%。粪肠球菌对不同抗生素的敏感性结果也相似。革兰氏阴性菌是UTI最常见的细菌病因,特别是大肠杆菌具有可比的敏感性结果
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引用次数: 0
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Sumatera Medical Journal
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