Background: Increased paternal age has been associated with an increased risk of spontaneous abortion, premature birth, infant mortality, congenital malformations, childhood cancer, epilepsy, autism, bipolar and schizophrenia in offspring. The biological mechanisms behind this relationship are not known but may be associated with de novo mutations and epigenetic changes in male cells with short and long term health consequences for their offspring. Males are responsible for most of the new mutations in the gene group, to the permanent distribution of reproductive cells and the number of mutations increases significantly with age. Objective: The aim of the study to determine the correlation between paternal age and onset of schizophrenia. Method: This study was correlation analysis with cross sectional approach with The subject is 92 schizophrenia patient. Analysis of the data using statistical test that is chi-square. Result: the study findings showed there was significant correlation between paternal age with schizophrenic aged onset of 0.001 (p <0.05).
{"title":"Relationship of Advanced Paternal Age and Onset of Schizophrenia","authors":"A. Widyastuty, D. P. Gultom, M. Husada","doi":"10.32734/SUMEJ.V2I1.715","DOIUrl":"https://doi.org/10.32734/SUMEJ.V2I1.715","url":null,"abstract":"Background: Increased paternal age has been associated with an increased risk of spontaneous abortion, premature birth, infant mortality, congenital malformations, childhood cancer, epilepsy, autism, bipolar and schizophrenia in offspring. The biological mechanisms behind this relationship are not known but may be associated with de novo mutations and epigenetic changes in male cells with short and long term health consequences for their offspring. Males are responsible for most of the new mutations in the gene group, to the permanent distribution of reproductive cells and the number of mutations increases significantly with age. \u0000Objective: The aim of the study to determine the correlation between paternal age and onset of schizophrenia. Method: This study was correlation analysis with cross sectional approach with The subject is 92 schizophrenia patient. Analysis of the data using statistical test that is chi-square. \u0000Result: the study findings showed there was significant correlation between paternal age with schizophrenic aged onset of 0.001 (p <0.05).","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130149649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The adverse reaction (AR) to intravenous contrast media (ICM) are relatively common. Various opinions pro-posed in the mechanism of the incidence of ICM AR. Suspected that the role of Immunoglobulin E (IgE) me-diates allergic conditions that are part of the AR. Objective:To determine the difference in total serum IgE level among subjects with and without ICM AR on computed tomography (CT) scan examination. To ob-serve difference in total serum IgE levels in subjects undergoing ICM adverse reaction based on the degree of severity. Method: An analytical study with cross-sectional design of 104 subjects undergoing CT scans with ICM, examined IgE levels before and after ICM was administered, then measured the severity of adverse re-actions of contrast media. Result: In this study, subjects undergoing adverse reactions, prior to administration Iopamidol had a higher mean IgE 1270.79 mg / dl compared with those who having AR 1174.90 mg / dl and after administration of Iopamidol a mean of Ig E is still higher in subjects having AR 1507.96 mg/dl com-pared with those having negative AR that is 1325.88 mg/dl, p = 0.696, statistically, not significant. Mild reac-tions in 40 subjects (38.5%) with cough, nausea, dizziness, itching, and sweating. Conclusion: Increase in total IgE levels in subjects with positive adverse reactions are independent(p=0.696).
静脉造影剂(ICM)的不良反应(AR)比较常见。对ICM性AR的发病机制提出了不同的看法，怀疑免疫球蛋白E (IgE)在过敏性AR中的作用。目的:确定ICM性AR患者和非ICM性AR患者在CT扫描检查时血清总IgE水平的差异。观察ICM不良反应不同严重程度患者血清总IgE水平的差异。方法:采用横断面设计对104例接受ICM CT扫描的患者进行分析研究，检测ICM前后的IgE水平，并测定造影剂不良反应的严重程度。结果:本研究中出现不良反应的受试者，服用Iopamidol前平均IgE为1270.79 mg/dl高于服用AR组的1174.90 mg/dl;服用Iopamidol后，服用AR组的平均IgE为1507.96 mg/dl高于服用AR组的1325.88 mg/dl, p = 0.696，无统计学意义。轻度反应40例(38.5%)，表现为咳嗽、恶心、头晕、瘙痒和出汗。结论:不良反应阳性受试者总IgE水平升高是独立的(p=0.696)。
{"title":"Difference in Total Serum Immunoglobulin E Level Among Patients With and Without Intravenous Contrast Media Adverse Reaction on Computed Tomography Scan Examination","authors":"Yulikha Ikhmawati, Z. Zubir, E. R. Daulay","doi":"10.32734/SUMEJ.V2I1.713","DOIUrl":"https://doi.org/10.32734/SUMEJ.V2I1.713","url":null,"abstract":"The adverse reaction (AR) to intravenous contrast media (ICM) are relatively common. Various opinions pro-posed in the mechanism of the incidence of ICM AR. Suspected that the role of Immunoglobulin E (IgE) me-diates allergic conditions that are part of the AR. Objective:To determine the difference in total serum IgE level among subjects with and without ICM AR on computed tomography (CT) scan examination. To ob-serve difference in total serum IgE levels in subjects undergoing ICM adverse reaction based on the degree of severity. Method: An analytical study with cross-sectional design of 104 subjects undergoing CT scans with ICM, examined IgE levels before and after ICM was administered, then measured the severity of adverse re-actions of contrast media. Result: In this study, subjects undergoing adverse reactions, prior to administration Iopamidol had a higher mean IgE 1270.79 mg / dl compared with those who having AR 1174.90 mg / dl and after administration of Iopamidol a mean of Ig E is still higher in subjects having AR 1507.96 mg/dl com-pared with those having negative AR that is 1325.88 mg/dl, p = 0.696, statistically, not significant. Mild reac-tions in 40 subjects (38.5%) with cough, nausea, dizziness, itching, and sweating. Conclusion: Increase in total IgE levels in subjects with positive adverse reactions are independent(p=0.696).","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130245960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Karo, A. P. Ketaren, R. Hasan, H. Hasan, Zulfikri Mukhtar, A. C. Lubis
Background : There were many studies proved that precordial ST depression in Inferior STEMI show LAD disease from angiografi, but there were also many who unproved . Altought LAD disease was not the main cause of precordial ST depression in Inferior STEMI, but there were many patients with Inferior STEMI who had high grade LAD disease. Sum of precordial ST depression is one of ECG criteria that can help us to prove it . The aim of this study in to know if there is corelation between sum of precordial ST depression with LAD disease and the severity of LAD disease in Inferior STEMI patients with precordial ST depression . Methods : We analized 60 patients inferior STEMI with precordial ST depression onset less than 24 hours that hospitalized in Haji Adam Malik General Hospital since December 2013-June 2017. Patients were divided in to 4 groups based on sum of precordial ST depression. Bivariate analysis were made to see the corelation between sum of precordial ST depression with LAD disease and severity of LAD, p value < 0.05 is statistically significant. Result : Bivariate analysis show that there is strong corelation between sum of precordial ST depression with LAD disease (p=0.01). Sum of precordial ST depression also corelate with severity of LAD (p=0.01). There are also corelation with location of the lesion in proximal LAD and the complexity of the lesion but not statistically significant (p=0.233 and p=0.102). Analysis ROC curve sum of precordial ST depression to LAD disease give the cut off ≥5.15 mm with sensitivity 70% and spesificity 76.2%(AUC 0,752 ,95% CI: 0,620 – 0,883 p<0,001) Conclusion : There is strong corelation between sum of precordial ST depression with high grade LAD disease. The more the sum of precordial ST depression the more posibility high degree LAD disease ( p=0.01).
{"title":"Corelation Between Sum of Precordial ST Depression in Acute Inferior Myocardial Infarction with Stenosis Severity of Left Anterior Descending Artery","authors":"K. Karo, A. P. Ketaren, R. Hasan, H. Hasan, Zulfikri Mukhtar, A. C. Lubis","doi":"10.32734/SUMEJ.V2I1.712","DOIUrl":"https://doi.org/10.32734/SUMEJ.V2I1.712","url":null,"abstract":"Background : There were many studies proved that precordial ST depression in Inferior STEMI show LAD disease from angiografi, but there were also many who unproved . Altought LAD disease was not the main cause of precordial ST depression in Inferior STEMI, but there were many patients with Inferior STEMI who had high grade LAD disease. Sum of precordial ST depression is one of ECG criteria that can help us to prove it . The aim of this study in to know if there is corelation between sum of precordial ST depression with LAD disease and the severity of LAD disease in Inferior STEMI patients with precordial ST depression . \u0000Methods : We analized 60 patients inferior STEMI with precordial ST depression onset less than 24 hours that hospitalized in Haji Adam Malik General Hospital since December 2013-June 2017. Patients were divided in to 4 groups based on sum of precordial ST depression. Bivariate analysis were made to see the corelation between sum of precordial ST depression with LAD disease and severity of LAD, p value < 0.05 is statistically significant. \u0000Result : Bivariate analysis show that there is strong corelation between sum of precordial ST depression with LAD disease (p=0.01). Sum of precordial ST depression also corelate with severity of LAD (p=0.01). There are also corelation with location of the lesion in proximal LAD and the complexity of the lesion but not statistically significant (p=0.233 and p=0.102). Analysis ROC curve sum of precordial ST depression to LAD disease give the cut off ≥5.15 mm with sensitivity 70% and spesificity 76.2%(AUC 0,752 ,95% CI: 0,620 – 0,883 p<0,001) \u0000Conclusion : There is strong corelation between sum of precordial ST depression with high grade LAD disease. The more the sum of precordial ST depression the more posibility high degree LAD disease ( p=0.01).","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131085555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indah Damayanti, Habibah Hanum Nasution, W. H. Lubis
Depression is psychosomatic disorder are common in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). Correlated with morbidity and mortality associated with chronic inflammation in patients, that characterized by elevated levels of plasma cytokines, especially interleukin (IL)-6. Objective: To investigate the correlation of depressive symptoms with IL-6 levels in patients with CKD who underwent regular HD. Methods: One hundred and 29 CKD patients were enrolled in this cross- sectional study. All eligible patients were screened for IL-6 level. Beck Depression Inventory (BDI) II questioner were then given to determine the presence of depression. Level of IL-6 was then correlated with BDI score using Spearman test. Result: The mean BDI score was 19,32 ± 6,18 indicating the level of mild depression symptoms, and the mean IL-6 level (8,697 ± 6,947 pg/mL) was still within normal range. There was a moderate positive correlation (r = 0.417) between the level of depressive symptoms and IL- 6 levels. Conclusion: There was a moderate positive correlation (r = 0.417) between IL-6 levels and depressive symptoms in patient with HD. However, mean IL-6 levels in depressive patients are still within normal limits indicating that the cause of depression is multifactorial.
{"title":"Correlation of Depression Symptoms and Interleukin-6 in Chronic Renal Disease with Regular Hemodialysis Patients","authors":"Indah Damayanti, Habibah Hanum Nasution, W. H. Lubis","doi":"10.32734/SUMEJ.V1I1.442","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.442","url":null,"abstract":"Depression is psychosomatic disorder are common in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). Correlated with morbidity and mortality associated with chronic inflammation in patients, that characterized by elevated levels of plasma cytokines, especially interleukin (IL)-6. Objective: To investigate the correlation of depressive symptoms with IL-6 levels in patients with CKD who underwent regular HD. Methods: One hundred and 29 CKD patients were enrolled in this cross- sectional study. All eligible patients were screened for IL-6 level. Beck Depression Inventory (BDI) II questioner were then given to determine the presence of depression. Level of IL-6 was then correlated with BDI score using Spearman test. Result: The mean BDI score was 19,32 ± 6,18 indicating the level of mild depression symptoms, and the mean IL-6 level (8,697 ± 6,947 pg/mL) was still within normal range. There was a moderate positive correlation (r = 0.417) between the level of depressive symptoms and IL- 6 levels. Conclusion: There was a moderate positive correlation (r = 0.417) between IL-6 levels and depressive symptoms in patient with HD. However, mean IL-6 levels in depressive patients are still within normal limits indicating that the cause of depression is multifactorial.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132708886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alfi Dewi Sholat, D. Gatot, Savina Handayani, A. I. Mardia, S. Syafril
In type 2 diabetes mellitus, there are changes in hemostasis components, including overexpression of PAI-1. By these facts, the authors are interested in conducting the study of PAI-1 level in diabetic patients with and without foot ulcer. Methods: The sample of this research was collected cross-sectionally on 20 type 2 diabetic patients with foot ulcer and 20 without foot ulcer. Blood samples were taken to measure serum PAI-1 level, complete blood count and hemostasis screening test. Results: Statistical analysis showed there are significant differences in hemoglobin, trombosit, Fibrinogen and D-dimer levels in the ulcer and non-ulcer groups but no significant difference in PAI-1 level. Conclusions: No higher PAI – 1 level were found in diabetic foot ulcer group than those without diabetic foot ulcer. There was no significant difference between PAI-1 level and grade of diabetic foot ulcer.
{"title":"Comparison Pai-1 Level in Type 2 Diabetes Mellitus with and Without Diabetic Foot Ulcer","authors":"Alfi Dewi Sholat, D. Gatot, Savina Handayani, A. I. Mardia, S. Syafril","doi":"10.32734/SUMEJ.V1I1.439","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.439","url":null,"abstract":"In type 2 diabetes mellitus, there are changes in hemostasis components, including overexpression of PAI-1. By these facts, the authors are interested in conducting the study of PAI-1 level in diabetic patients with and without foot ulcer. Methods: The sample of this research was collected cross-sectionally on 20 type 2 diabetic patients with foot ulcer and 20 without foot ulcer. Blood samples were taken to measure serum PAI-1 level, complete blood count and hemostasis screening test. Results: Statistical analysis showed there are significant differences in hemoglobin, trombosit, Fibrinogen and D-dimer levels in the ulcer and non-ulcer groups but no significant difference in PAI-1 level. Conclusions: No higher PAI – 1 level were found in diabetic foot ulcer group than those without diabetic foot ulcer. There was no significant difference between PAI-1 level and grade of diabetic foot ulcer.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130964259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irwan Pernandi Sagala, D. Munir, A.Y.M. Rambe, T. Ashar
Introduction: Chronic exposure of volatile substances can cause the impaired olfactory function. Objectives: In order to identify the difference of olfactory function in the workers of the Gas Station in Medan city. Methods: Analytical research with cross- sectional approach. The research subjects were 80 persons consisting of 40 gas station operators and 40 non-operators who fulfilled the inclusion and exclusion criteria. The applied statistical analysis was Mann Whitney, Fisher's Exact, Chi Square, T independent, Spearman with 95% confidence level. Results: Proportion of the impaired olfactory function in the gas station operator group by 77.5% and non-operator group by 0%. Significant correlation was obtained between age, duration of work with the impaired olfactory function (p = 0,047, p = 0,001). The gas station operators will suffer the impaired olfactory function if they work for 3.89 years. Conclusions: There were differences of olfactory functions in the gas station workers by using Sniffin 'Sticks Test in Medan city.
{"title":"The Difference of Olfactory Functions in The Workers of The Gas Station by Using Sniffin’ Stickstest in Medan City","authors":"Irwan Pernandi Sagala, D. Munir, A.Y.M. Rambe, T. Ashar","doi":"10.32734/SUMEJ.V1I1.446","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.446","url":null,"abstract":"Introduction: Chronic exposure of volatile substances can cause the impaired olfactory function. Objectives: In order to identify the difference of olfactory function in the workers of the Gas Station in Medan city. Methods: Analytical research with cross- sectional approach. The research subjects were 80 persons consisting of 40 gas station operators and 40 non-operators who fulfilled the inclusion and exclusion criteria. The applied statistical analysis was Mann Whitney, Fisher's Exact, Chi Square, T independent, Spearman with 95% confidence level. Results: Proportion of the impaired olfactory function in the gas station operator group by 77.5% and non-operator group by 0%. Significant correlation was obtained between age, duration of work with the impaired olfactory function (p = 0,047, p = 0,001). The gas station operators will suffer the impaired olfactory function if they work for 3.89 years. Conclusions: There were differences of olfactory functions in the gas station workers by using Sniffin 'Sticks Test in Medan city.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129207134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
World Health Organization (WHO) recommends to continue breastfeeding until two years of age. There are few studies assessing the correlation between breastfeeding duration and motor development. A cross-sectional study was conducted in April 2016 in Muara Batang Gadis District. The sample were children 3-6 years of age. Breastfeeding duration was obtained by interview, and motor development was assessed using Denver Developmental Screening Test II. Chi-square test was used to evaluate the correlation between breastfeeding duration and motor development, with P-value <0.05 and 95% Confidence Interval (CI). Among 204 children, 5.4% had the fine motor delay, and 1% had the gross motor delay. Children with breastfeeding duration for at least for two years had better fine motor development compared to breastfeeding duration for less than two years (P<0.001, PR=1.139, 95% CI=1.055-1.231) and there is no difference in gross motor development (P=0.193, PR=1.023, 95% CI=0.991-1.055). There is a correlation between breastfeeding duration and fine motor development.
{"title":"Correlation between Breastfeeding Duration and Motor Development in Children","authors":"Gurnal Rai Gandra Siregar, M. Lubis, I. Fujiati","doi":"10.32734/SUMEJ.V1I1.440","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.440","url":null,"abstract":"World Health Organization (WHO) recommends to continue breastfeeding until two years of age. There are few studies assessing the correlation between breastfeeding duration and motor development. A cross-sectional study was conducted in April 2016 in Muara Batang Gadis District. The sample were children 3-6 years of age. Breastfeeding duration was obtained by interview, and motor development was assessed using Denver Developmental Screening Test II. Chi-square test was used to evaluate the correlation between breastfeeding duration and motor development, with P-value <0.05 and 95% Confidence Interval (CI). Among 204 children, 5.4% had the fine motor delay, and 1% had the gross motor delay. Children with breastfeeding duration for at least for two years had better fine motor development compared to breastfeeding duration for less than two years (P<0.001, PR=1.139, 95% CI=1.055-1.231) and there is no difference in gross motor development (P=0.193, PR=1.023, 95% CI=0.991-1.055). There is a correlation between breastfeeding duration and fine motor development.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122667055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.2991/phico-16.2017.35
D. Sari, Z. Tala, S. Lestari, S. V. Hutagalung, R. A. Ganie, Delina Sekar Harum
Background: Study showed that 95% women had serum level of 25(OH)D lower than normal and women have riskier lifestyle than men, this is based on women’s lifestyle, such as avoiding sun rays, sunblock application, low vitamin D intake, and low physical activity. As result of the deficiency, there will be increasing number of metabolic disorders such as obesity and diabetes mellitus type 2.Objectives: To discover lifestyle, knowledge, attitude, and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder caused by vitamin D deficiency.Method: Cross-sectional study engaging 98 women participants with vitamin D deficiency-insufficiency. Lifestyle including avoiding sunlight, low physical activity, and sunblock application were assessed. The scoring was to assess knowledge, attitude and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder in Medan and then the result was analyzed.Result: The study engaged 98 women aged 20-50 years old with vitamin D deficiency-insufficiency, showed vitamin D level with mean 19.66±5.69 ng/ml. There were 95% participants categorized into vitamin D deficiency-insufficiency and 5% participants categorized into vitamin D suficiency. All subjects were found to be low on sun rays exposure, high incidence sunblock applicaton, low vitamin D intake, and low physical activities. According to knowledge about risk of metabolic disorder, there were 42.3% participants with sufficient knowledge and 57.7% with deficient knowledge, and regarding attitude, 48.52% had negative attitude and 51.5% had positive attitude, regarding action, 24.7% was sufficient and 75.3% was deficient. According to the analysis, there was no significant association between action and knowledge, attitude and knowledge, but there was significant association between action and knowledge based on education (p=0.01).Conclusion: Lifestyle, sufficient knowledge, and action could be the caused of low vitamin D level. There was significant association between action and knowledge based on education, but didn’t show any associations. Based on this result, knowledge needs to be improved in order to improve attitude and action with counseling or books that are easy to be understood about the importance of vitamin D
{"title":"ANALYSIS OF LIFESTYLE, KNOWLEDGE, ATTITUDE, AND KNOWLEDGE OF WOMEN AGED 20-50 YEARS OLD WITH VITAMIN D DEFICIENCY-INSUFFICIENCY IN NORTH SUMATERA, INDONESIA","authors":"D. Sari, Z. Tala, S. Lestari, S. V. Hutagalung, R. A. Ganie, Delina Sekar Harum","doi":"10.2991/phico-16.2017.35","DOIUrl":"https://doi.org/10.2991/phico-16.2017.35","url":null,"abstract":"Background: Study showed that 95% women had serum level of 25(OH)D lower than normal and women have riskier lifestyle than men, this is based on women’s lifestyle, such as avoiding sun rays, sunblock application, low vitamin D intake, and low physical activity. As result of the deficiency, there will be increasing number of metabolic disorders such as obesity and diabetes mellitus type 2.Objectives: To discover lifestyle, knowledge, attitude, and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder caused by vitamin D deficiency.Method: Cross-sectional study engaging 98 women participants with vitamin D deficiency-insufficiency. Lifestyle including avoiding sunlight, low physical activity, and sunblock application were assessed. The scoring was to assess knowledge, attitude and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder in Medan and then the result was analyzed.Result: The study engaged 98 women aged 20-50 years old with vitamin D deficiency-insufficiency, showed vitamin D level with mean 19.66±5.69 ng/ml. There were 95% participants categorized into vitamin D deficiency-insufficiency and 5% participants categorized into vitamin D suficiency. All subjects were found to be low on sun rays exposure, high incidence sunblock applicaton, low vitamin D intake, and low physical activities. According to knowledge about risk of metabolic disorder, there were 42.3% participants with sufficient knowledge and 57.7% with deficient knowledge, and regarding attitude, 48.52% had negative attitude and 51.5% had positive attitude, regarding action, 24.7% was sufficient and 75.3% was deficient. According to the analysis, there was no significant association between action and knowledge, attitude and knowledge, but there was significant association between action and knowledge based on education (p=0.01).Conclusion: Lifestyle, sufficient knowledge, and action could be the caused of low vitamin D level. There was significant association between action and knowledge based on education, but didn’t show any associations. Based on this result, knowledge needs to be improved in order to improve attitude and action with counseling or books that are easy to be understood about the importance of vitamin D","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125625764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Although brain tumors only 1.4% of all tumors, high fatality rate made these tumors need special attention. In North Sumatera, there is no data on brain tumors patients profile. Objective: To determine brain tumor patients’ profile in North Sumatera, Indonesia. Method: A descriptive hospital-based study with primary data which taken from September–December 2012. Result: Of 75 brain tumors patients surveyed in 10 hospitals in North Sumatera 38 (50.7%) patients were male and 37 (49.3%) patients were female. Mean of age was 51.45 (11–87) years old. Most of the subjects were housewifes, 26 (34.7%) patients. The most common cause that brought these patients to see doctors was headache 32 (42.7%), followed by decreased level of consciousness 17 (22.7%). Clinical manifestations found in these patients were headache 67 (89.3%), dizziness/vertigo 41 (54.7%), convulsion 22 (29.3%), vomitting 32 (42.7%), motor dysfunction 46 (61.3%), sensory dysfunction 21 (28%), and cognitive decline 21 (28%). Only 7 patients (9.3%) had history of tumor in his/her relatives. Eighteen patients (24%) were treated surgically and 8 (10.7%) were given radiotherapy. 71 patients were alive (94.7%) when discharged from the hospitals due to various reasons. Head CT Scan/MRI showed primary tumors in 56 (74.7%) patients. Of these primary tumors 25 (44.6%) patients were meningioma and 19 (33.9%) were astrocytoma. Of 19 (25.3%) patients with secondary tumor, most common primary tumor where found in the lung 11 (57.9%). Conclusion: Sex the patients were equally distributed with mean of age was 51.45 (11–87) years old. The most common cause that brought these patients to seek for treatment were headache. Most of these patients were treated conservatively. The most common head CT Scan/MRI findings showed primary tumors.
{"title":"Profile of Brain Tumor Patients in 10 Hospitals in North Sumatera","authors":"A. Rambe, A. Fitri, Tonam Tonam","doi":"10.32734/SUMEJ.V1I1.443","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.443","url":null,"abstract":"Although brain tumors only 1.4% of all tumors, high fatality rate made these tumors need special attention. In North Sumatera, there is no data on brain tumors patients profile. Objective: To determine brain tumor patients’ profile in North Sumatera, Indonesia. Method: A descriptive hospital-based study with primary data which taken from September–December 2012. Result: Of 75 brain tumors patients surveyed in 10 hospitals in North Sumatera 38 (50.7%) patients were male and 37 (49.3%) patients were female. Mean of age was 51.45 (11–87) years old. Most of the subjects were housewifes, 26 (34.7%) patients. The most common cause that brought these patients to see doctors was headache 32 (42.7%), followed by decreased level of consciousness 17 (22.7%). Clinical manifestations found in these patients were headache 67 (89.3%), dizziness/vertigo 41 (54.7%), convulsion 22 (29.3%), vomitting 32 (42.7%), motor dysfunction 46 (61.3%), sensory dysfunction 21 (28%), and cognitive decline 21 (28%). Only 7 patients (9.3%) had history of tumor in his/her relatives. Eighteen patients (24%) were treated surgically and 8 (10.7%) were given radiotherapy. 71 patients were alive (94.7%) when discharged from the hospitals due to various reasons. Head CT Scan/MRI showed primary tumors in 56 (74.7%) patients. Of these primary tumors 25 (44.6%) patients were meningioma and 19 (33.9%) were astrocytoma. Of 19 (25.3%) patients with secondary tumor, most common primary tumor where found in the lung 11 (57.9%). Conclusion: Sex the patients were equally distributed with mean of age was 51.45 (11–87) years old. The most common cause that brought these patients to seek for treatment were headache. Most of these patients were treated conservatively. The most common head CT Scan/MRI findings showed primary tumors.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116679562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL). Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occures in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complain about cosmetics appereances, itching or discomfort experienced. Objective: The aim of our study was to assess the impact of skin tag lesion on quality of life of patients. Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik General Hospital, Medan from September 2016 to October 2016. The patients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL. Result: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients. Conclusion: In this study’s we concluded skin tag does not affect the quality of life of the patients.
{"title":"Quality of Life Assessment in Skin Tag Patients","authors":"I. Putra, N. Jusuf, Johan Kartayana","doi":"10.32734/SUMEJ.V1I1.444","DOIUrl":"https://doi.org/10.32734/SUMEJ.V1I1.444","url":null,"abstract":"Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL). Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occures in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complain about cosmetics appereances, itching or discomfort experienced. Objective: The aim of our study was to assess the impact of skin tag lesion on quality of life of patients. Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik General Hospital, Medan from September 2016 to October 2016. The patients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL. Result: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients. Conclusion: In this study’s we concluded skin tag does not affect the quality of life of the patients.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124891415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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