Pub Date : 2021-01-20DOI: 10.32734/sumej.v4i1.5111
Yongky Wijaya, R. Muzasti
Peripheral Arterial Disease (PAD) is the narrowing of peripheral blood vessels which prevalence is high in the elders. In 2010, it was estimated that 202 million people were suffering from PAD, most of which are in developing countries, especially the Southeast Asia region. Inflammation markers such as leukocyte and C-Reactive Protein (CRP) can predict the incidence of PAD but their use in determining prognosis remains unclear. Complications in PAD include amputation, increased cardiovascular events, and even death. Aim: This study aims to determine the relationship between leukocyte and CRP level on complications in PAD, in the forms of amputation, cardiovascular events, and mortality. Methods: This is a meta analysis study which uses online literature sourced from Pubmed, Science Direct, Cochrane, and Google Scholar. Results: Based on the data analysis, there is a significant relationship between CRP with the incidence of amputation (HR 1.24, 95%CI: 1.02-1.49, p=0.03) and hs-CRP with cardiovascular events (HR 1.33, 95%CI: 1.10-1.60, p=0.003). Leukocyte on the other hand shows no significant relationship with the incidence of amputation (OR 1.10, 95%CI: 0.98-1.23, p=0.10) and mortality (OR 1.14, 95%CI: 0.97-1.35, p=0.12)
{"title":"C-Reactive Protein and Leukocyte as Predictors of Complications in Peripheral Arterial Disease","authors":"Yongky Wijaya, R. Muzasti","doi":"10.32734/sumej.v4i1.5111","DOIUrl":"https://doi.org/10.32734/sumej.v4i1.5111","url":null,"abstract":"Peripheral Arterial Disease (PAD) is the narrowing of peripheral blood vessels which prevalence is high in the elders. In 2010, it was estimated that 202 million people were suffering from PAD, most of which are in developing countries, especially the Southeast Asia region. Inflammation markers such as leukocyte and C-Reactive Protein (CRP) can predict the incidence of PAD but their use in determining prognosis remains unclear. Complications in PAD include amputation, increased cardiovascular events, and even death. Aim: This study aims to determine the relationship between leukocyte and CRP level on complications in PAD, in the forms of amputation, cardiovascular events, and mortality. Methods: This is a meta analysis study which uses online literature sourced from Pubmed, Science Direct, Cochrane, and Google Scholar. Results: Based on the data analysis, there is a significant relationship between CRP with the incidence of amputation (HR 1.24, 95%CI: 1.02-1.49, p=0.03) and hs-CRP with cardiovascular events (HR 1.33, 95%CI: 1.10-1.60, p=0.003). Leukocyte on the other hand shows no significant relationship with the incidence of amputation (OR 1.10, 95%CI: 0.98-1.23, p=0.10) and mortality (OR 1.14, 95%CI: 0.97-1.35, p=0.12)","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132068437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-20DOI: 10.32734/sumej.v4i1.3758
Siti Nadhila, Tri Widyawati
Abstract. The aging process occurs in all parts of the body including the face. One of the factors that can influence this process is free radicals which can be suppressed by antioxidants. Grapes (Vitis vinifera) are known to contain high antioxidant compounds. This research was conducted to determine the anti-aging activity of grape ethanol extract (V. vinifera) in clay mask preparations. Grape ethanol extract obtained by maceration and formulated in clay mask dosage form with 4 concentrations namely FI (2.5%), FII (5%), FIII (7.5%) and F0 as a control. A total of 12 volunteers who met the inclusion criteria were applied to the mask every week for 4 weeks and evaluated the water content, smoothness, large pores, many blemishes and facial skin wrinkles before and after application in each treatment. Mask stability was evaluated for 12 weeks at room temperature. Data were analyzed by the Kruskal Wallis and Friedman tests. After 4 weeks of treatment, the highest changes including humidity (12.63%), pore size (50%), blemishes (57.32%) and wrinkles (75.69%) were found in FIII. While changes in skin smoothness were found in FII by 34.04%. There was a significant moisture difference between F0-FIII (p <0.05), a significant difference in evenness between F0-FI, F0-FII and F0-FIII (p <0.05), a significant difference in spots between F0-FIII (p < 0.05) and significant differences in wrinkles between F0-FIII (p <0.05). Grape ethanol extract in clay mask preparations has anti-aging activity.
{"title":"The Effect of Ethanol Extract of Grape (Vitis vinifera) as an Anti-Aging for Women in Productive Age","authors":"Siti Nadhila, Tri Widyawati","doi":"10.32734/sumej.v4i1.3758","DOIUrl":"https://doi.org/10.32734/sumej.v4i1.3758","url":null,"abstract":"Abstract. The aging process occurs in all parts of the body including the face. One of the factors that can influence this process is free radicals which can be suppressed by antioxidants. Grapes (Vitis vinifera) are known to contain high antioxidant compounds. This research was conducted to determine the anti-aging activity of grape ethanol extract (V. vinifera) in clay mask preparations. Grape ethanol extract obtained by maceration and formulated in clay mask dosage form with 4 concentrations namely FI (2.5%), FII (5%), FIII (7.5%) and F0 as a control. A total of 12 volunteers who met the inclusion criteria were applied to the mask every week for 4 weeks and evaluated the water content, smoothness, large pores, many blemishes and facial skin wrinkles before and after application in each treatment. Mask stability was evaluated for 12 weeks at room temperature. Data were analyzed by the Kruskal Wallis and Friedman tests. After 4 weeks of treatment, the highest changes including humidity (12.63%), pore size (50%), blemishes (57.32%) and wrinkles (75.69%) were found in FIII. While changes in skin smoothness were found in FII by 34.04%. There was a significant moisture difference between F0-FIII (p <0.05), a significant difference in evenness between F0-FI, F0-FII and F0-FIII (p <0.05), a significant difference in spots between F0-FIII (p < 0.05) and significant differences in wrinkles between F0-FIII (p <0.05). Grape ethanol extract in clay mask preparations has anti-aging activity. \u0000 ","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125161067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-20DOI: 10.32734/SUMEJ.V3I2.3305
Muhammad Khairi Akbar Fikar Siregar, R. Rivany
The incidence of cervical cancer is still quite high. It is never separated from the risk factors that influence it. Some of them are sexually active, relatively young marital age, have high parity, use of contraception, and smoking can increase a woman's potential for cervical cancer. The aim of this study was to determine the characteristics of patients about the risk factors for cervical cancer in Haji Adam Malik General Hospital, Medan in 2016-2018. This research method uses descriptive observational design with cross sectional using medical record data. The results of this study using consecutive sampling techniques, took 100 samples and obtained several characteristics are age of patients, age of marriage, marriage history, number of parities, use of contraception, and smoking history. From this study it can be concluded that the characteristics of the incidence of cervical cancer in the General Hospital of Haji Adam Malik Medan in 2016-2018 are 50-59 years old, marital age ≤ 20 years old, married once, multigravida, uses injection type of hormonal contraception , and not smoking .
{"title":"Cervical Cancer Risk Factors at Haji Adam Malik General Hospital Medan 2016-2018","authors":"Muhammad Khairi Akbar Fikar Siregar, R. Rivany","doi":"10.32734/SUMEJ.V3I2.3305","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I2.3305","url":null,"abstract":"The incidence of cervical cancer is still quite high. It is never separated from the risk factors that influence it. Some of them are sexually active, relatively young marital age, have high parity, use of contraception, and smoking can increase a woman's potential for cervical cancer. The aim of this study was to determine the characteristics of patients about the risk factors for cervical cancer in Haji Adam Malik General Hospital, Medan in 2016-2018. This research method uses descriptive observational design with cross sectional using medical record data. The results of this study using consecutive sampling techniques, took 100 samples and obtained several characteristics are age of patients, age of marriage, marriage history, number of parities, use of contraception, and smoking history. From this study it can be concluded that the characteristics of the incidence of cervical cancer in the General Hospital of Haji Adam Malik Medan in 2016-2018 are 50-59 years old, marital age ≤ 20 years old, married once, multigravida, uses injection type of hormonal contraception , and not smoking .","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123607804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-20DOI: 10.32734/sumej.v4i1.5587
Muhammad Farid Zulkhair Damanik, H. Yulfi
Introduction. Scabies is often found in Indonesia, which is due to its tropical climate. Data showed that the prevalence of scabies Indonesia in 2013 was 6%. Poor personal hygiene, low socioeconomic status, and non-supporting health behavior are also some of the risk factors. Objectives. To identify the relationship between personal hygiene behavior with scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan. Methods. This is an analytical study using cross sectional design. The sample was all the students from grade 7-12. The data was taken cardinal signs of scabies and microscopic examination towards the scrapped skin. The risk factors on personal behavior was taken thru questionnaire and direct observation on the research site. Results. The incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan is 81 out of 220 respondent (36,8%). There is a strong correlation between personal hygiene behavior with incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan (p=0,001). The environmental sanitation is categorized poor according to 3 aspects including clean water availability, occupant density, and personal storage availability. Conclusion. There is a strong correlation between personal hygiene behavior with the incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan.
介绍。疥疮经常在印度尼西亚发现，这是由于它的热带气候。数据显示，2013年印度尼西亚疥疮流行率为6%。不良的个人卫生、低社会经济地位和非支持性健康行为也是一些危险因素。目标。目的:探讨哥打棉兰市Pondok Pesantren Modern Darul Hikmah疥疮与个人卫生行为的关系。方法。这是一项采用横断面设计的分析性研究。样本为7-12年级的所有学生。数据采取疥疮的主要迹象和显微镜检查对报废的皮肤。通过问卷调查和现场直接观察，了解影响个人行为的危险因素。结果。Pondok Pesantren Modern Darul Hikmah Kota棉兰的疥疮发病率为220名应答者中的81人(36.8%)。Pondok Pesantren Modern Darul Hikmah Kota Medan的个人卫生行为与疥疮发病率之间存在很强的相关性(p= 0.001)。环境卫生根据3个方面被分类为差，包括清洁水的可用性、居住者密度和个人储存的可用性。结论。在Pondok Pesantren Modern Darul Hikmah Kota棉兰，个人卫生行为与疥疮发病率之间存在很强的相关性。
{"title":"The Relationship Between Personal Hygiene Behavior With The Incidence Of Scabies In Pondok Pesantren Modern Darul Hikmah Kota Medan","authors":"Muhammad Farid Zulkhair Damanik, H. Yulfi","doi":"10.32734/sumej.v4i1.5587","DOIUrl":"https://doi.org/10.32734/sumej.v4i1.5587","url":null,"abstract":"Introduction. Scabies is often found in Indonesia, which is due to its tropical climate. Data showed that the prevalence of scabies Indonesia in 2013 was 6%. Poor personal hygiene, low socioeconomic status, and non-supporting health behavior are also some of the risk factors. Objectives. To identify the relationship between personal hygiene behavior with scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan. Methods. This is an analytical study using cross sectional design. The sample was all the students from grade 7-12. The data was taken cardinal signs of scabies and microscopic examination towards the scrapped skin. The risk factors on personal behavior was taken thru questionnaire and direct observation on the research site. Results. The incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan is 81 out of 220 respondent (36,8%). There is a strong correlation between personal hygiene behavior with incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan (p=0,001). The environmental sanitation is categorized poor according to 3 aspects including clean water availability, occupant density, and personal storage availability. Conclusion. There is a strong correlation between personal hygiene behavior with the incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125799298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-20DOI: 10.32734/sumej.v4i1.3735
Tifanny Tantoso, M. S. Sitorus, L. Feriyawati, D. Wahyuni
Obesity is a worldwide problem that has been steadily increasing even in developing countries. Obesity has been linked to various types of cancer, one of which is breast cancer. Breast cancer has been classified into various types based on gene and hormone receptor expressions, which offered new insights to therapies and prognoses. We conducted a case-control study using 42 breast cancer patients and 43 healthy women, all of which are older than 55 years of age and have experienced menopause, and for case subjects, additional immunohistochemistry profiles have been provided. Data were collected by interviews and medical records. For data analysis, we used Pearson’s Chi-Square test and Fisher’s Exact test. Results showed that high BMI is significantly associated with breast cancer, and risk is elevated (p < 0.05, OR = 1.263, 95% CI = 1.007-1.583). No significant association with molecular subtypes was observed.
肥胖是一个世界性的问题，甚至在发展中国家也在稳步增长。肥胖与多种癌症有关，其中之一就是乳腺癌。根据基因和激素受体的表达将乳腺癌分为不同的类型，这为治疗和预后提供了新的见解。我们对42名乳腺癌患者和43名健康女性进行了一项病例对照研究，这些女性年龄均大于55岁并经历了更年期，对于病例受试者，我们提供了额外的免疫组织化学谱。通过访谈和医疗记录收集数据。对于数据分析，我们使用皮尔逊卡方检验和费雪精确检验。结果显示，高BMI与乳腺癌显著相关，且风险升高(p < 0.05, OR = 1.263, 95% CI = 1.007-1.583)。未观察到与分子亚型有显著关联。
{"title":"High BMI leads to increased breast cancer risk in postmenopausal women","authors":"Tifanny Tantoso, M. S. Sitorus, L. Feriyawati, D. Wahyuni","doi":"10.32734/sumej.v4i1.3735","DOIUrl":"https://doi.org/10.32734/sumej.v4i1.3735","url":null,"abstract":"Obesity is a worldwide problem that has been steadily increasing even in developing countries. Obesity has been linked to various types of cancer, one of which is breast cancer. Breast cancer has been classified into various types based on gene and hormone receptor expressions, which offered new insights to therapies and prognoses. We conducted a case-control study using 42 breast cancer patients and 43 healthy women, all of which are older than 55 years of age and have experienced menopause, and for case subjects, additional immunohistochemistry profiles have been provided. Data were collected by interviews and medical records. For data analysis, we used Pearson’s Chi-Square test and Fisher’s Exact test. Results showed that high BMI is significantly associated with breast cancer, and risk is elevated (p < 0.05, OR = 1.263, 95% CI = 1.007-1.583). No significant association with molecular subtypes was observed.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123979072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-20DOI: 10.32734/sumej.v3i3.3682
Ulfatul Ulya, Ashri Yudhistira, A. Y. Rambe, Yetty Machrina
Abstract. Sinonasal tumor is a neoplasm that arises from nasal and paranasal sinus tissue. It is rarely found, only <3% of all malignancy in head and neck, and 1% of all malignancy in the body. Although it is rarely found, it can cause serious complication in adult. Unspecific sign and symptoms of sinonasal tumor often make the patients ignore the disease. It leads to the diagnosis of this disease becomes late and the patients come to the doctor in advanced stage. This research was conducted to know about the profile of sinonasal tumor patients in H. Adam Malik Medan Hospital on 2016-2018. The study was a descriptive study with retrospective approach. The data used are secondary data taken from medical records. The data were analyzed using a statistical application programs. Sinonasal tumor patients in RSUP HAM Medan are 158 patients, where 95 patients met the inclusion criteria, consisting of 24 benign tumors (25,3%) and 71 malignant tumors (74,7%). The majority of patients are male (71,6%), and the highest age group in in 51-60 years old (31,6%). The main complaints felt by the patients were nasal symptoms (64,2%), the location of tumors mostly found in nasal cavity (50,5%), the most histopathological type is NKSCC (43,2%), the most occupation is self-employment (26%), and the treatment of the patients are surgery (29,5%). Keyword: Sinonasal Tumor, Profile, Sinonasal Cancer
摘要鼻窦肿瘤是一种起源于鼻窦和副鼻窦组织的肿瘤。它很少见，仅占头颈部所有恶性肿瘤的<3%，占全身所有恶性肿瘤的1%。虽然罕见，但在成人中可引起严重的并发症。鼻窦肿瘤的症状和体征不明确，常使患者忽视本病。这导致该病的诊断较晚，患者在晚期才去看医生。本研究旨在了解美丹医院2016-2018年鼻窦肿瘤患者情况。本研究为回顾性描述性研究。所使用的数据是从医疗记录中获取的辅助数据。采用统计应用程序对数据进行分析。RSUP HAM Medan的鼻窦肿瘤患者158例，其中95例符合纳入标准，其中良性肿瘤24例(25.3%)，恶性肿瘤71例(74.7%)。患者以男性居多(71.6%)，51 ~ 60岁年龄组最多(31.6%)。患者主诉为鼻部症状(64.2%)，肿瘤部位以鼻腔居多(50.5%)，组织病理类型以NKSCC居多(43.2%)，职业以自营职业居多(26%)，治疗方式以手术为主(29.5%)。关键词:鼻窦肿瘤，剖面图，鼻窦癌
{"title":"PROFILE OF SINONASAL TUMOR PATIENT IN ADAM MALIK GENERAL HOSPITAL 2016-2018","authors":"Ulfatul Ulya, Ashri Yudhistira, A. Y. Rambe, Yetty Machrina","doi":"10.32734/sumej.v3i3.3682","DOIUrl":"https://doi.org/10.32734/sumej.v3i3.3682","url":null,"abstract":"Abstract. Sinonasal tumor is a neoplasm that arises from nasal and paranasal sinus tissue. It is rarely found, only <3% of all malignancy in head and neck, and 1% of all malignancy in the body. Although it is rarely found, it can cause serious complication in adult. Unspecific sign and symptoms of sinonasal tumor often make the patients ignore the disease. It leads to the diagnosis of this disease becomes late and the patients come to the doctor in advanced stage. This research was conducted to know about the profile of sinonasal tumor patients in H. Adam Malik Medan Hospital on 2016-2018. The study was a descriptive study with retrospective approach. The data used are secondary data taken from medical records. The data were analyzed using a statistical application programs. Sinonasal tumor patients in RSUP HAM Medan are 158 patients, where 95 patients met the inclusion criteria, consisting of 24 benign tumors (25,3%) and 71 malignant tumors (74,7%). The majority of patients are male (71,6%), and the highest age group in in 51-60 years old (31,6%). The main complaints felt by the patients were nasal symptoms (64,2%), the location of tumors mostly found in nasal cavity (50,5%), the most histopathological type is NKSCC (43,2%), the most occupation is self-employment (26%), and the treatment of the patients are surgery (29,5%). \u0000Keyword: Sinonasal Tumor, Profile, Sinonasal Cancer","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133790294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-20DOI: 10.32734/sumej.v4i3.6416
Tazzya Shailla Elfazi, Cut Aria Arina
Abstract. Stroke is a clinical sign that develops rapidly due to a disturbance of Focal (or global) brain function, with symptoms lasting for 24 hours or more, can lead to death, without any other cause than vascular. In Indonesia it is estimated that every year there are 500,000 inhabitants affected by stroke. One of the risk factors of stroke is the unhealthy lifestyle, such as smoking. The harmful content contained in cigarettes can become oxidizing substances in the blood so that there is damage to the artery walls and will be the location of fat-saving, platelet cells, cholesterol, and the thickening of the smooth muscle layers of the artery walls resulting in an aterotrombotic. This is what can cause a stroke. Goal. To know the relationship between smoking and the incidence of stroke in RSUP Haji Adam Malik Medan in 2018. Method. This type of research is analytic research with cross-sectional design. The data used in this research is secondary data that is data of the medical record of ischemic stroke patients and hemorrhagic stroke patients years 2018 obtained from RSUP Haji Adam Malik Medan medical record installation. The research method used is non-randomized consecutive sampling, with a side-total technique. The Data obtained is subsequently processed by computerization. Results. The hypothesis testing was conducted using a Chi-square test at a signification level of p < 0.05 and obtained a P value of 0.000 and also prevelence ratio > 1 with a value of 1.7418. Conclusion. There is a significant relationship between smoking and the incidence of stroke, especially in the event of ischemic stroke in RSUP Haji Adam Malik Medan in 2018.
摘要中风是一种因大脑局部（或整体）功能紊乱而迅速发展的临床表现，症状持续 24 小时或更长时间，可导致死亡，除血管原因外没有其他原因。据估计，印度尼西亚每年有 50 万居民受到中风的影响。中风的危险因素之一是不健康的生活方式，如吸烟。香烟中含有的有害成分会成为血液中的氧化物质，从而对动脉壁造成损害，并将成为脂肪储蓄、血小板细胞、胆固醇的位置，动脉壁平滑肌层的增厚导致动脉粥样硬化。这就是导致中风的原因。目标了解2018年RSUP Haji Adam Malik棉兰分校吸烟与中风发病率之间的关系。方法。本研究类型为横断面设计的分析研究。本研究使用的数据是二手数据，即从RSUP Haji Adam Malik Medan医疗记录安装中获得的2018年缺血性中风患者和出血性中风患者的医疗记录数据。使用的研究方法是非随机连续抽样，并采用侧面总计技术。获得的数据随后通过计算机进行处理。研究结果假设检验采用卡方检验（Chi-square test），P<0.05，P值为0.000，流行率>1，值为1.7418。结论吸烟与中风发病率之间存在明显关系，尤其是在2018年棉兰市RSUP Haji Adam Malik的缺血性中风事件中。
{"title":"The Relationship between Smoking and The Incidence of Stroke at Haji Adam Malik General Hospital in 2018","authors":"Tazzya Shailla Elfazi, Cut Aria Arina","doi":"10.32734/sumej.v4i3.6416","DOIUrl":"https://doi.org/10.32734/sumej.v4i3.6416","url":null,"abstract":"Abstract. Stroke is a clinical sign that develops rapidly due to a disturbance of Focal (or global) brain function, with symptoms lasting for 24 hours or more, can lead to death, without any other cause than vascular. In Indonesia it is estimated that every year there are 500,000 inhabitants affected by stroke. One of the risk factors of stroke is the unhealthy lifestyle, such as smoking. The harmful content contained in cigarettes can become oxidizing substances in the blood so that there is damage to the artery walls and will be the location of fat-saving, platelet cells, cholesterol, and the thickening of the smooth muscle layers of the artery walls resulting in an aterotrombotic. This is what can cause a stroke. Goal. To know the relationship between smoking and the incidence of stroke in RSUP Haji Adam Malik Medan in 2018. Method. This type of research is analytic research with cross-sectional design. The data used in this research is secondary data that is data of the medical record of ischemic stroke patients and hemorrhagic stroke patients years 2018 obtained from RSUP Haji Adam Malik Medan medical record installation. The research method used is non-randomized consecutive sampling, with a side-total technique. The Data obtained is subsequently processed by computerization. Results. The hypothesis testing was conducted using a Chi-square test at a signification level of p < 0.05 and obtained a P value of 0.000 and also prevelence ratio > 1 with a value of 1.7418. Conclusion. There is a significant relationship between smoking and the incidence of stroke, especially in the event of ischemic stroke in RSUP Haji Adam Malik Medan in 2018.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127573424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-20DOI: 10.32734/sumej.v3i3.3686
Nichitri Agina Ginting, Betty
Abstract. Breast cancer is the most kind of cancer that happens to women, and it’s one of the cancer that can cause the major death in the world and in Indonesia. Breast cancer cases at age are very young tend to have lower percentages of old age, but have a bad prognosis. Family history of breast cancer because of the BRCA1 and BRCA2 mutation . Objective. The aim of this research is to study about breast cancer very young age profile in H. Adam Malik Medan General Hospital. From 2016-2018 based on age, family history and grading histology. Methods. In this descriptive research with cross-sectional study, the sample were collected from medical record of breast cancer patient in H. Adam Malik Medan General Hospital. This research use total sampling method and matched with inclusion and exclusion criteria. Results. Total of the sample is 160 subject. The majority of age group is 31-35 year’s old (81 subject or 51,0%). The majority of age menarche group is <12 year’s old (104 subject or 65,5%). Do not have family history (82 subject or 51,3%), and have a family history just found (78 subject or 48,8%). The majority of grading histology is grade 3 (68 subject or 42,5%). Conclusion. Sufferers of breast cancer at very young age is quite a lot with grade 3 on grading histology.Keyword: breast cancer, very young age, family history. Abstrak. Latar Belakang. Kanker payudara merupakan kanker yang paling sering terjadi pada wanita, dan merupakan salah satu kanker yang dapat menyebabkan kematian utama di dunia dan di Indonesia. Kasus kanker payudara pada usia sangat muda cenderung memiliki presentase yang lebih rendah diantara usia tua, namun memiliki prognosis yang lebih buruk. Riwayat keluarga pada kanker payudara dikarenakan adanya mutasi BRCA1 dan BRCA2. Tujuan. Mengetahui profil kanker payudara wanita pada usia sangat muda di Rumah Sakit Umum Pusat Haji Adam Malik Medan. Tahun 2016-2018 berdasarkan usia, riwayat keluarga dan grading histologi. Metode. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross-sectional. Penelitian ini dilakukan menggunakan data sekunder melalui data rekam medis penderita kanker payudara di Rumah Sakit Umum Pusat Haji Adam Malik Medan. Besar sampel ditentukan dengan metode total sampling dan disesuaikan dengan kriteria inklusi dan eksklusi. Hasil. Diperoleh total 160 sampel. Kelompok usia terbanyak adalah usia 31-35 tahun sebanyak 81 penderita (51,0%). Usia menarche terbanyak pada kelompok usia <12 tahun sebanyak 104 penderita (65,5%). Tidak memiliki riwayat keluarga sebanyak 82 penderita (51,3%), dan memiliki riiwayat keluarga ditemukan sebanyak 78 penderita (48,8%). Grading histologi terbanyak adalah grade 3 sebanyak 68 penderita (42,5%). Kesimpulan. Penderita kanker payudara pada usia sangat muda cukup banyak dengan grade 3 pada grading histologi.Kata Kunci: kanker payudara, usia sangat muda, riwayat keluarga
摘要乳腺癌是发生在女性身上的最常见的癌症，也是世界上和印度尼西亚最主要的死亡原因之一。年龄很小的乳腺癌病例往往老年比例较低，但预后较差。由于BRCA1和BRCA2突变而有乳腺癌家族史。目标。本研究的目的是研究H. Adam Malik Medan总医院非常年轻的乳腺癌概况。2016-2018年根据年龄、家族史和组织学分级。方法。本研究采用横断面研究的描述性研究方法，样本收集于H. Adam Malik Medan总医院的乳腺癌患者病历。本研究采用全抽样方法，并匹配纳入标准和排除标准。结果。样本总数为160人。年龄以31-35岁为主(81例，占51.0%)。初潮年龄组以<12岁者居多(104例，占65.5%)。没有家族史(82例，51.3%)，家族史刚刚发现(78例，48.8%)。大多数组织学评分为3级(68个科目或42.5%)。结论。在很小的时候就患有乳腺癌的患者在组织学上是3级的。关键词:乳腺癌，很小的时候，家族史。Abstrak。Latar Belakang。Kanker payudara merupakan Kanker yang paling sering terjadi padwanita, dan merupakan salah satu Kanker yang dapat menyebabkan kematian utama di duunia dandi Indonesia。Kasus kanker, payudara, pagada, sangat muda, cenderung memiliki, yang lebih, renda, diantara usia tuk, namun memiliki预后yang lebih burk。Riwayat keluarga padkanker payudara dikarenakan adanya mutasi BRCA1和BRCA2。Tujuan。Mengetahui简介kanker payudara wanita padusia sangat muda di Rumah Sakit Umum Pusat Haji Adam Malik Medan。Tahun 2016-2018 berdasarkan usia, riwayat keluarga丹分级组织学。Metode。Penelitian ini merupakan Penelitian deskriptif dengan pendekatan横截面。Penelitian ini dilakukan menggunakan data sekunder melalui data rekam media is penderita kanker payudara di Rumah Sakit Umum Pusat Haji Adam Malik Medan。Besar样品差异与登革方法，总取样与不取样与登革标准的差异与登革方法有关。Hasil。共160个样品。Kelompok usia terbanyak adalah usia 31-35 tahun sebanyak 81 penderita(51.0%)。Usia menarche terbanyak padkelompok Usia <12 tahun sebanyak 104 penderita(65,5%)。Tidak memiliki riwayat keluarga sebanyak 82 penderita (51.3%)， dan memiliki riiwayat keluarga ditemukan sebanyak 78 penderita(48.8%)。组织学分级terbanyak adalah 3级sebanyak 68 penderita(42.5%)。Kesimpulan。Penderita kanker payudara pada usia sangat muda cuup banyak dengan 3级pada分级组织学。Kata Kunci: kanker payudara, usia sangat muda, riwayat keluarga
{"title":"BREAST CANCER PROFILE IN VERY YOUNG WOMEN AT HAJI ADAM MALIK GENERAL HOSPITAL MEDAN","authors":"Nichitri Agina Ginting, Betty","doi":"10.32734/sumej.v3i3.3686","DOIUrl":"https://doi.org/10.32734/sumej.v3i3.3686","url":null,"abstract":"Abstract. Breast cancer is the most kind of cancer that happens to women, and it’s one of the cancer that can cause the major death in the world and in Indonesia. Breast cancer cases at age are very young tend to have lower percentages of old age, but have a bad prognosis. Family history of breast cancer because of the BRCA1 and BRCA2 mutation . Objective. The aim of this research is to study about breast cancer very young age profile in H. Adam Malik Medan General Hospital. From 2016-2018 based on age, family history and grading histology. Methods. In this descriptive research with cross-sectional study, the sample were collected from medical record of breast cancer patient in H. Adam Malik Medan General Hospital. This research use total sampling method and matched with inclusion and exclusion criteria. Results. Total of the sample is 160 subject. The majority of age group is 31-35 year’s old (81 subject or 51,0%). The majority of age menarche group is <12 year’s old (104 subject or 65,5%). Do not have family history (82 subject or 51,3%), and have a family history just found (78 subject or 48,8%). The majority of grading histology is grade 3 (68 subject or 42,5%). Conclusion. Sufferers of breast cancer at very young age is quite a lot with grade 3 on grading histology.Keyword: breast cancer, very young age, family history. \u0000Abstrak. Latar Belakang. Kanker payudara merupakan kanker yang paling sering terjadi pada wanita, dan merupakan salah satu kanker yang dapat menyebabkan kematian utama di dunia dan di Indonesia. Kasus kanker payudara pada usia sangat muda cenderung memiliki presentase yang lebih rendah diantara usia tua, namun memiliki prognosis yang lebih buruk. Riwayat keluarga pada kanker payudara dikarenakan adanya mutasi BRCA1 dan BRCA2. Tujuan. Mengetahui profil kanker payudara wanita pada usia sangat muda di Rumah Sakit Umum Pusat Haji Adam Malik Medan. Tahun 2016-2018 berdasarkan usia, riwayat keluarga dan grading histologi. Metode. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross-sectional. Penelitian ini dilakukan menggunakan data sekunder melalui data rekam medis penderita kanker payudara di Rumah Sakit Umum Pusat Haji Adam Malik Medan. Besar sampel ditentukan dengan metode total sampling dan disesuaikan dengan kriteria inklusi dan eksklusi. Hasil. Diperoleh total 160 sampel. Kelompok usia terbanyak adalah usia 31-35 tahun sebanyak 81 penderita (51,0%). Usia menarche terbanyak pada kelompok usia <12 tahun sebanyak 104 penderita (65,5%). Tidak memiliki riwayat keluarga sebanyak 82 penderita (51,3%), dan memiliki riiwayat keluarga ditemukan sebanyak 78 penderita (48,8%). Grading histologi terbanyak adalah grade 3 sebanyak 68 penderita (42,5%). Kesimpulan. Penderita kanker payudara pada usia sangat muda cukup banyak dengan grade 3 pada grading histologi.Kata Kunci: kanker payudara, usia sangat muda, riwayat keluarga","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115091045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-12DOI: 10.32734/SUMEJ.V3I3.4047
S. Yenny, Y. Suryani
Skin aging is a complex biological process influenced by a combination of intrinsic and extrinsic factors, leading to cumulative alterations of skin struture, function and appearance. Polyphenols represent a superfamily of diverse naturally occurring phytochemicals. Current research reveals that phenolic compounds in plants possess high antioxidant activity and free radical scavenging capacity and can prevent the body from oxidative damage over human life span. This review focuses on present understanding of skin aging and the effects of polyphenols in the context of anti-agieng activity.
{"title":"Polyphenols as Natural Antioxidants in Skin Aging","authors":"S. Yenny, Y. Suryani","doi":"10.32734/SUMEJ.V3I3.4047","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I3.4047","url":null,"abstract":"Skin aging is a complex biological process influenced by a combination of intrinsic and extrinsic factors, leading to cumulative alterations of skin struture, function and appearance. Polyphenols represent a superfamily of diverse naturally occurring phytochemicals. Current research reveals that phenolic compounds in plants possess high antioxidant activity and free radical scavenging capacity and can prevent the body from oxidative damage over human life span. This review focuses on present understanding of skin aging and the effects of polyphenols in the context of anti-agieng activity. \u0000 ","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121063251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-20DOI: 10.32734/SUMEJ.V3I2.3601
Adetya Indah Sari Matondang, D. Paramita
Abstract. Burn injuries is a damaged or loss of skin caused by a contact with either high temperature sources or very low temperature sources. Burn injuries is classified according to its etiology, depth and extend of the wound. The extend of the burn can be determined by calculating TBSA (Total Body Surface Area). Wider TBSA will cause lower serum albumin levels due to a higher percentage increase. The purpose of this study was to determine the association between the extend of burn injuries with albumin levels on burn injury patients at Haji Adam Malik General Hospital Medan in 2017-2018. This research uses observational research with cross-sectional research design, using secondary data obtained from medical records at Haji Adam Malik General Hospital Medan in 2017-2018. The research sample was selected by using the total sampling method from all medical record data that met the research criteria. In this study, significant results were obtained with a value of p = 0.006 (p < 0.05) between the extend of burn injuries and albumin levels in burn injury patients at Haji Adam Malik General Hospital Medan in 2017-2018. Keyword: Burn injury, Albumin, TBSA, RSUP Haji Adam Malik, Medan
{"title":"The Association between the Extend of Burn Injuries with Albumin Level on Burn Injury patients","authors":"Adetya Indah Sari Matondang, D. Paramita","doi":"10.32734/SUMEJ.V3I2.3601","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I2.3601","url":null,"abstract":"Abstract. Burn injuries is a damaged or loss of skin caused by a contact with either high temperature sources or very low temperature sources. Burn injuries is classified according to its etiology, depth and extend of the wound. The extend of the burn can be determined by calculating TBSA (Total Body Surface Area). Wider TBSA will cause lower serum albumin levels due to a higher percentage increase. The purpose of this study was to determine the association between the extend of burn injuries with albumin levels on burn injury patients at Haji Adam Malik General Hospital Medan in 2017-2018. This research uses observational research with cross-sectional research design, using secondary data obtained from medical records at Haji Adam Malik General Hospital Medan in 2017-2018. The research sample was selected by using the total sampling method from all medical record data that met the research criteria. In this study, significant results were obtained with a value of p = 0.006 (p < 0.05) between the extend of burn injuries and albumin levels in burn injury patients at Haji Adam Malik General Hospital Medan in 2017-2018. \u0000Keyword: Burn injury, Albumin, TBSA, RSUP Haji Adam Malik, Medan \u0000 ","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128431951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：