Objectives To evaluate the relationship between sexual myths and sexual function among women. Background Sexual myths are false beliefs about sexuality that are not related to proven scientific evidence. They are spread through the transmission of false and exaggerated information and are shaped and fueled by the imagination of the community. Patients and methods The current study was carried out after approval by the Dermatology and Andrology Department and Medical Ethics Committee, Faculty of Medicine, Menoufia University. Results There was no statistically significant relationship between sexual function and sexual myths among women, such as immoral woman initiates sexual activity, seafood increases desire, fatty meals increase desire, first sexual intercourse is always painful, blood is a sign of virginity, masturbation could rupture hymen, as well as masturbation is harmful (P > 0.05). There was no statistically significant relationship between sexual function and sexual myths among women such as oral sex is religiously forbidden, oral sex transmits infection, female sexual areas are dirty, genital cutting prevents sexual arousal, pregnancy decreases desire, intercourse is forbidden during pregnancy, as well as women have less sexual desire (P > 0.05). Conclusion From the results of the present study, we have found that participants had a high number of wrong beliefs. Despite the presence of these myths among women, there was no effect on sexual function, as majority of cases have fair sexual function.
{"title":"Relationship between sexual myths and sexual function among women","authors":"Mohammed Gaber, Asmaa Shaban, Hend Emara","doi":"10.4103/mmj.mmj_289_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_289_22","url":null,"abstract":"Objectives To evaluate the relationship between sexual myths and sexual function among women. Background Sexual myths are false beliefs about sexuality that are not related to proven scientific evidence. They are spread through the transmission of false and exaggerated information and are shaped and fueled by the imagination of the community. Patients and methods The current study was carried out after approval by the Dermatology and Andrology Department and Medical Ethics Committee, Faculty of Medicine, Menoufia University. Results There was no statistically significant relationship between sexual function and sexual myths among women, such as immoral woman initiates sexual activity, seafood increases desire, fatty meals increase desire, first sexual intercourse is always painful, blood is a sign of virginity, masturbation could rupture hymen, as well as masturbation is harmful (P > 0.05). There was no statistically significant relationship between sexual function and sexual myths among women such as oral sex is religiously forbidden, oral sex transmits infection, female sexual areas are dirty, genital cutting prevents sexual arousal, pregnancy decreases desire, intercourse is forbidden during pregnancy, as well as women have less sexual desire (P > 0.05). Conclusion From the results of the present study, we have found that participants had a high number of wrong beliefs. Despite the presence of these myths among women, there was no effect on sexual function, as majority of cases have fair sexual function.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"26 1","pages":"1703 - 1708"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88190047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadik Sadik, A. Rady, Norhan Hamouda, Alaaelddin Elsakka
Objectives To compare the perioperative analgesic efficacy of serratus anterior plan block (SAPB) versus paravertebral block in patients undergoing mastectomy surgery. Background Patients undergoing mastectomy surgery often experience severe postoperative pain. Inadequate control of this pain increases the risk of postoperative complications and may develop into chronic pain. Patients and methods This prospective randomized trial was carried out on 60 female patients, American Society of Anesthesiologists I–III, 30–60 years old, scheduled for modified radical mastectomy, between April 2020 and March 2021. The patients were randomly allocated into one of two groups (30 patients each). Group S received ultrasound-guided SAPB and group P received ultrasound-guided thoracic paravertebral block (TPVB). In both blocks, the injectate was 20-ml bupivacaine 0.25% with epinephrine (5 μg/ml) and fentanyl (2 μg/ml). Both blocks were performed as a single injection after general anesthesia induction. Intraoperative fentanyl consumption, postoperative visual analog scale scores, time-to-first ketorolac request, total postoperative ketorolac consumption, and patients' satisfaction were recorded. Data were analyzed by SPSS, version 26, Mann–Whitney test, Student t test, and variance test. Results Both groups had comparable intraoperative fentanyl consumption (P = 0.15). However TPVB was associated with significantly lower postoperative analgesic requirements, longer time to first analgesic request, and higher grade of patient satisfaction (P < 0.001). Visual analog scale scores were significantly lower in group P at 2, 3, 8, and 17 h (P < 0.001) while being comparable at the remaining time points. Conclusion TPVB and SAPB were associated with comparable intraoperative analgesic efficacy; however, TPVB was associated with a better postoperative analgesic profile and patient satisfaction.
{"title":"Analgesic efficacy of serratus anterior plane block versus paravertebral block in mastectomy surgery","authors":"Sadik Sadik, A. Rady, Norhan Hamouda, Alaaelddin Elsakka","doi":"10.4103/mmj.mmj_254_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_254_22","url":null,"abstract":"Objectives To compare the perioperative analgesic efficacy of serratus anterior plan block (SAPB) versus paravertebral block in patients undergoing mastectomy surgery. Background Patients undergoing mastectomy surgery often experience severe postoperative pain. Inadequate control of this pain increases the risk of postoperative complications and may develop into chronic pain. Patients and methods This prospective randomized trial was carried out on 60 female patients, American Society of Anesthesiologists I–III, 30–60 years old, scheduled for modified radical mastectomy, between April 2020 and March 2021. The patients were randomly allocated into one of two groups (30 patients each). Group S received ultrasound-guided SAPB and group P received ultrasound-guided thoracic paravertebral block (TPVB). In both blocks, the injectate was 20-ml bupivacaine 0.25% with epinephrine (5 μg/ml) and fentanyl (2 μg/ml). Both blocks were performed as a single injection after general anesthesia induction. Intraoperative fentanyl consumption, postoperative visual analog scale scores, time-to-first ketorolac request, total postoperative ketorolac consumption, and patients' satisfaction were recorded. Data were analyzed by SPSS, version 26, Mann–Whitney test, Student t test, and variance test. Results Both groups had comparable intraoperative fentanyl consumption (P = 0.15). However TPVB was associated with significantly lower postoperative analgesic requirements, longer time to first analgesic request, and higher grade of patient satisfaction (P < 0.001). Visual analog scale scores were significantly lower in group P at 2, 3, 8, and 17 h (P < 0.001) while being comparable at the remaining time points. Conclusion TPVB and SAPB were associated with comparable intraoperative analgesic efficacy; however, TPVB was associated with a better postoperative analgesic profile and patient satisfaction.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"68 1","pages":"1910 - 1914"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78826635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives The aim of the study was to evaluate serum ghrelin in nonobese patients with moderate-to-severe acne vulgaris. Background Acne vulgaris is a multifactorial disease that affects mostly the adolescent population, but it is difficult to predict those who are prone to severe forms. Patients and methods A case–control study was conducted on 80 participants selected from the Dermatology Outpatient Clinic at Menoufia University Hospital during the period of study from March 2019 till December 2020. Full history taking and clinical and dermatological examinations were done. Serum ghrelin level was measured using the enzyme-linked immunosorbent assay. Results There was highly statistically significant difference between the two studied groups regarding serum ghrelin level. There was significant negative correlation between the severity according to The Global Acne Grading System with serum ghrelin level groups in terms of fasting glucose level, triglycerides, total cholesterol, low-density lipoprotein, and high-density lipoprotein. Conclusion There is a relationship between acne vulgaris and the level of ghrelin hormone, which is decreased in the serum of acne patients.
{"title":"Evaluation of serum ghrelin in patients with acne vulgaris","authors":"M. Basha, Maathir El-Shafei, Donya Boraey","doi":"10.4103/mmj.mmj_244_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_244_22","url":null,"abstract":"Objectives The aim of the study was to evaluate serum ghrelin in nonobese patients with moderate-to-severe acne vulgaris. Background Acne vulgaris is a multifactorial disease that affects mostly the adolescent population, but it is difficult to predict those who are prone to severe forms. Patients and methods A case–control study was conducted on 80 participants selected from the Dermatology Outpatient Clinic at Menoufia University Hospital during the period of study from March 2019 till December 2020. Full history taking and clinical and dermatological examinations were done. Serum ghrelin level was measured using the enzyme-linked immunosorbent assay. Results There was highly statistically significant difference between the two studied groups regarding serum ghrelin level. There was significant negative correlation between the severity according to The Global Acne Grading System with serum ghrelin level groups in terms of fasting glucose level, triglycerides, total cholesterol, low-density lipoprotein, and high-density lipoprotein. Conclusion There is a relationship between acne vulgaris and the level of ghrelin hormone, which is decreased in the serum of acne patients.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"31 1","pages":"1662 - 1667"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78832114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahy Egiz, Mohammed Sayed, Alaa Abdelgaied, Dalia Elkhuly, S. El-deeb
Objective To determine the benefit of assessment of cervicovaginal placental alpha-microglobulin 1 (PAMG-1) with the cervical biometry in prediction of preterm labor (PTL). Background Many screening methods are now used for the diagnosis of PTL. Short cervix in the second trimester, detected by transvaginal ultrasound, was significantly related to PTL. The presence of PAMG-1 in cervicovaginal discharge of women with clinically intact membranes is indicative of imminent delivery. Patients and methods This prospective longitudinal study was conducted on 90 pregnant women and divided into two equal groups: group A included 45 pregnant women between 24+0 and 36+6 weeks with threatened PTL and short cervix, and group B included 45 pregnant women at the same age group without threatened PTL symptoms and with normal cervical biometry. Results Women of preterm group had statistically significant shorter cervical length (15.6% <15 mm, 48.9% between 15 and 20 mm, and 35.6% between 20 and 24 mm; P ≤ 0.001) and more detectable positive cervicovaginal fluid PAMG-1 (32 vs. 0; P < 0.001). Cervical PAMG-1 had a sensitivity of 71.11%, a specificity of 100.0%, a positive predictive value of 100%, a negative predictive value of 77.59, and an accuracy of 85.56%. Moreover, there was a strong correlation between positive PAMG and time of delivery, as 18.8% gave birth in first 48 h, 50.0% gave birth between 2 and 7 days, and 31.3% gave birth after 7 days. On the contrary, all women with negative PAMG gave birth after 7 days. Conclusions Regular use of the two tests described could help identify low-risk patients and lower the number of unnecessary hospitalizations and treatments.
{"title":"The predictive value of cervical biometry and placental alpha-microglobulin 1 in cervicovaginal fluid in preterm labor","authors":"Mahy Egiz, Mohammed Sayed, Alaa Abdelgaied, Dalia Elkhuly, S. El-deeb","doi":"10.4103/mmj.mmj_228_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_228_22","url":null,"abstract":"Objective To determine the benefit of assessment of cervicovaginal placental alpha-microglobulin 1 (PAMG-1) with the cervical biometry in prediction of preterm labor (PTL). Background Many screening methods are now used for the diagnosis of PTL. Short cervix in the second trimester, detected by transvaginal ultrasound, was significantly related to PTL. The presence of PAMG-1 in cervicovaginal discharge of women with clinically intact membranes is indicative of imminent delivery. Patients and methods This prospective longitudinal study was conducted on 90 pregnant women and divided into two equal groups: group A included 45 pregnant women between 24+0 and 36+6 weeks with threatened PTL and short cervix, and group B included 45 pregnant women at the same age group without threatened PTL symptoms and with normal cervical biometry. Results Women of preterm group had statistically significant shorter cervical length (15.6% <15 mm, 48.9% between 15 and 20 mm, and 35.6% between 20 and 24 mm; P ≤ 0.001) and more detectable positive cervicovaginal fluid PAMG-1 (32 vs. 0; P < 0.001). Cervical PAMG-1 had a sensitivity of 71.11%, a specificity of 100.0%, a positive predictive value of 100%, a negative predictive value of 77.59, and an accuracy of 85.56%. Moreover, there was a strong correlation between positive PAMG and time of delivery, as 18.8% gave birth in first 48 h, 50.0% gave birth between 2 and 7 days, and 31.3% gave birth after 7 days. On the contrary, all women with negative PAMG gave birth after 7 days. Conclusions Regular use of the two tests described could help identify low-risk patients and lower the number of unnecessary hospitalizations and treatments.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"6 1","pages":"1964 - 1969"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90197401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives The aim was to assess the role of leukocyte estrase reagent strips and myeloperoxidase (MPO) for diagnosing spontaneous bacterial peritonitis (SBP) in cirrhotic patients. Background Liver cirrhosis represents one of the major causes of death worldwide. Cirrhotic patients with ascites show a higher susceptibility to bacterial infections with SBP that is the most frequent infectious complication. The gold standard for diagnosing SBP is a polymorphonuclear neutrophil count of 250 cells/μl in ascitic fluid. Urine reagent strips have been proposed as a rapid and inexpensive alternative. MPO has a preoxidant–proinflammatory property and its level increases in cases of infection. Patients and methods In total, 90 patients with decompensated chronic liver disease and ascites participated in this study, including (Group I) 20 patients having no symptoms and PMN count (<250 cells/mm3), (Group II) 35 patients with a picture of SBP and PMN count <250 cells/mm3, and (Group III) 35 symptomatic patients with PMN count >250 cells/mm3. Ascitic PMN count and MPO level were measured. Also, ascetic fluid samples were assessed by leukocyte esterase reagent strips (LERS). Results The mean value of MPO was statistically significantly higher in group III (1640.1 ± 480.6 ng/ml) than group II (595.4 ± 201.3 ng/ml) than group I (479.2 ± 236.2 ng/ml). The cutoff value of ascetic MPO was greater than 959.7 ng/ml with accuracy 100%. The mean value of LERS was significantly higher in group III (230 ± 210.8) than group I (14 ± 10.2) and group II (13 ± 9.9). The cutoff value of LERS was greater than 15 leukocytes/μl with accuracy 76%. Conclusion Rapid bedside diagnostic tests for SBP could be performed using MPO and LERS.
{"title":"Role of leukocyte estrase reagent strips and myeloperoxidase for diagnosing spontaneous bacterial peritonitis","authors":"A. Ali, Eman Elsayed Badr, Alaa Metawea, A. Teima","doi":"10.4103/mmj.mmj_141_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_141_22","url":null,"abstract":"Objectives The aim was to assess the role of leukocyte estrase reagent strips and myeloperoxidase (MPO) for diagnosing spontaneous bacterial peritonitis (SBP) in cirrhotic patients. Background Liver cirrhosis represents one of the major causes of death worldwide. Cirrhotic patients with ascites show a higher susceptibility to bacterial infections with SBP that is the most frequent infectious complication. The gold standard for diagnosing SBP is a polymorphonuclear neutrophil count of 250 cells/μl in ascitic fluid. Urine reagent strips have been proposed as a rapid and inexpensive alternative. MPO has a preoxidant–proinflammatory property and its level increases in cases of infection. Patients and methods In total, 90 patients with decompensated chronic liver disease and ascites participated in this study, including (Group I) 20 patients having no symptoms and PMN count (<250 cells/mm3), (Group II) 35 patients with a picture of SBP and PMN count <250 cells/mm3, and (Group III) 35 symptomatic patients with PMN count >250 cells/mm3. Ascitic PMN count and MPO level were measured. Also, ascetic fluid samples were assessed by leukocyte esterase reagent strips (LERS). Results The mean value of MPO was statistically significantly higher in group III (1640.1 ± 480.6 ng/ml) than group II (595.4 ± 201.3 ng/ml) than group I (479.2 ± 236.2 ng/ml). The cutoff value of ascetic MPO was greater than 959.7 ng/ml with accuracy 100%. The mean value of LERS was significantly higher in group III (230 ± 210.8) than group I (14 ± 10.2) and group II (13 ± 9.9). The cutoff value of LERS was greater than 15 leukocytes/μl with accuracy 76%. Conclusion Rapid bedside diagnostic tests for SBP could be performed using MPO and LERS.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"55 1","pages":"1746 - 1752"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89341415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives This study aimed to assess serum brain-derived neurotrophic factor (BDNF) levels in female patients with acne vulgaris and to assess the relationship of this biomarker to the degree of psychological symptoms developed in these patients. Background Acne vulgaris is a benign self-limited condition. However, patients usually endure anxiety, depression, poor body image, frustration, anger, diminished confidence and self-esteem, social isolation, and restriction of activities because it commonly affects the face during a sociosexually critical age, causing a considerable cosmetic concern with adverse social and psychological consequences on the quality of life. Patients and methods Serum BDNF levels were measured in 60 female patients with acne vulgaris divided into three groups according to the severity and 30 age- and sex-matched healthy controls using enzyme-linked immunosorbent assay. Patients filled a Dermatology Life Quality Index questionnaire; both patients and controls filled a Hospital Anxiety and Depression Scale (HADS) and Perceived Stress Scale-10 (PSS) questionnaires. Results Serum BDNF levels were significantly lower in acne patients when compared with healthy controls and those levels were lowest in the severe group. HADS and PSS scores of the patients were significantly higher than those in the control group. Statistically significant negative correlations were found between serum BDNF levels and scores. Conclusion Serum BDNF levels decreased significantly in acne vulgaris, indicating the role it may play in the development of psychological symptoms, which make patients with acne more liable to anxiety, depression, and stress.
{"title":"Serum levels of brain-derived neurotrophic factor, association with psychological symptoms in females with acne vulgaris","authors":"M. Hagag, R. Azmy, Enas Deshesh","doi":"10.4103/mmj.mmj_274_21","DOIUrl":"https://doi.org/10.4103/mmj.mmj_274_21","url":null,"abstract":"Objectives This study aimed to assess serum brain-derived neurotrophic factor (BDNF) levels in female patients with acne vulgaris and to assess the relationship of this biomarker to the degree of psychological symptoms developed in these patients. Background Acne vulgaris is a benign self-limited condition. However, patients usually endure anxiety, depression, poor body image, frustration, anger, diminished confidence and self-esteem, social isolation, and restriction of activities because it commonly affects the face during a sociosexually critical age, causing a considerable cosmetic concern with adverse social and psychological consequences on the quality of life. Patients and methods Serum BDNF levels were measured in 60 female patients with acne vulgaris divided into three groups according to the severity and 30 age- and sex-matched healthy controls using enzyme-linked immunosorbent assay. Patients filled a Dermatology Life Quality Index questionnaire; both patients and controls filled a Hospital Anxiety and Depression Scale (HADS) and Perceived Stress Scale-10 (PSS) questionnaires. Results Serum BDNF levels were significantly lower in acne patients when compared with healthy controls and those levels were lowest in the severe group. HADS and PSS scores of the patients were significantly higher than those in the control group. Statistically significant negative correlations were found between serum BDNF levels and scores. Conclusion Serum BDNF levels decreased significantly in acne vulgaris, indicating the role it may play in the development of psychological symptoms, which make patients with acne more liable to anxiety, depression, and stress.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"62 1","pages":"1709 - 1714"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87992530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives To present the various adverse effects of topical prostaglandin analogs on the periorbita. Background The authors studied the prostaglandin-related adverse effects on the periorbita and compared each analog in a sample of patients with glaucoma. Patients and methods A case series study was performed on the adverse effects on the periorbita noticed in glaucomatous patients who were controlled by prostaglandin in Menoufia University Hospital and Cairo Fatemic Hospital. The study was done on 100 patients aged from 18 to 75 years at outpatient clinics. Results A total of 100 patients were found to have a variety of disorders, including deepening of the superior sulci (42/100), hypertrichosis (23/100), lengthening of eyelashes (48/100), and hyperpigmentation of the skin surrounding the eye (40/100). Conclusion Although topical prostaglandin analogs are well tolerated by many patients, some individuals who use these medications complain of structural changes in the periorbita, resulting in a variety of cosmetic and eyelid disorders, such as lengthening of eyelashes, hypertrichosis, hyperpigmentation of the skin surrounding the eye, and deepening of sulci.
{"title":"Study of the effect of prostaglandin analogs on the periorbita of glaucomatous patients","authors":"Hoda El Sobky, Sameh S Mandour, Amr Awwad","doi":"10.4103/mmj.mmj_255_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_255_22","url":null,"abstract":"Objectives To present the various adverse effects of topical prostaglandin analogs on the periorbita. Background The authors studied the prostaglandin-related adverse effects on the periorbita and compared each analog in a sample of patients with glaucoma. Patients and methods A case series study was performed on the adverse effects on the periorbita noticed in glaucomatous patients who were controlled by prostaglandin in Menoufia University Hospital and Cairo Fatemic Hospital. The study was done on 100 patients aged from 18 to 75 years at outpatient clinics. Results A total of 100 patients were found to have a variety of disorders, including deepening of the superior sulci (42/100), hypertrichosis (23/100), lengthening of eyelashes (48/100), and hyperpigmentation of the skin surrounding the eye (40/100). Conclusion Although topical prostaglandin analogs are well tolerated by many patients, some individuals who use these medications complain of structural changes in the periorbita, resulting in a variety of cosmetic and eyelid disorders, such as lengthening of eyelashes, hypertrichosis, hyperpigmentation of the skin surrounding the eye, and deepening of sulci.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"89 1","pages":"2027 - 2031"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87414282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Till now, salivary C-reactive protein (CRP), mean platelet volume (MPV), and neutrophil-lymphocyte ratio (NLR) have not been studied as markers for diagnosis of neonatal sepsis. Objectives To assess the applicability of salivary CRP, MPV, and NLR as diagnostic markers in preterm neonates with neonatal sepsis. Patients and methods A case–control study was conducted on 184 newborns from the neonatal ICU at Menoufia University Hospital and Qwesna General Hospital from 2021 to 2022. All selected newborns were divided into group I, which included 92 neonates diagnosed as having neonatal sepsis, and group II, which included 92 apparently healthy neonates. Full history taking; thorough clinical examination; laboratory investigations such as complete blood count, leukocyte count, platelet number, NLR, platelet-lymphocyte ratio, serum CRP, salivary CRP, and blood culture; and radiological investigation such as chest radiograph and cranial ultrasound were done. Results Salivary CRP, MPV, and NLR were significantly increased in the case group than the control group. The cutoff values of MPV, NLR, and salivary CRP were 8.4, 1.87, and 8.0, respectively, with sensitivity of 82.6, 97.8, and 98.9%, respectively, and specificity of 97.8, 98.9, and 100%, respectively, for detection of neonatal sepsis. Conclusion Salivary CPR, MPV, and NLR were significantly increased in neonatal sepsis than healthy neonates. However, platelet-lymphocyte ratio was not significant in neonatal sepsis.
{"title":"Salivary C-reactive protein, mean platelet volume, and neutrophil-lymphocyte ratio as diagnostic markers of neonatal sepsis","authors":"S. Ragab, H. El-Sayed, S. El-deeb, Rehab El-Arabi","doi":"10.4103/mmj.mmj_208_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_208_22","url":null,"abstract":"Background Till now, salivary C-reactive protein (CRP), mean platelet volume (MPV), and neutrophil-lymphocyte ratio (NLR) have not been studied as markers for diagnosis of neonatal sepsis. Objectives To assess the applicability of salivary CRP, MPV, and NLR as diagnostic markers in preterm neonates with neonatal sepsis. Patients and methods A case–control study was conducted on 184 newborns from the neonatal ICU at Menoufia University Hospital and Qwesna General Hospital from 2021 to 2022. All selected newborns were divided into group I, which included 92 neonates diagnosed as having neonatal sepsis, and group II, which included 92 apparently healthy neonates. Full history taking; thorough clinical examination; laboratory investigations such as complete blood count, leukocyte count, platelet number, NLR, platelet-lymphocyte ratio, serum CRP, salivary CRP, and blood culture; and radiological investigation such as chest radiograph and cranial ultrasound were done. Results Salivary CRP, MPV, and NLR were significantly increased in the case group than the control group. The cutoff values of MPV, NLR, and salivary CRP were 8.4, 1.87, and 8.0, respectively, with sensitivity of 82.6, 97.8, and 98.9%, respectively, and specificity of 97.8, 98.9, and 100%, respectively, for detection of neonatal sepsis. Conclusion Salivary CPR, MPV, and NLR were significantly increased in neonatal sepsis than healthy neonates. However, platelet-lymphocyte ratio was not significant in neonatal sepsis.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"10 1","pages":"1810 - 1815"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73151602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fady Elgendy, Nouran Aboelkhair, Nesma El-Desokyc, Hanan Z El-Sayed
Objectives To assess the diagnostic value of the urinary intestinal fatty acid-binding protein (iFABP) in neonatal necrotizing enterocolitis (NEC) in the early stage of the disease. Background NEC is a severe acute gastrointestinal disease affecting preterm newborns. iFABP has been associated with injury to the intestinal mucosa common to NEC. Patients and methods This cross-sectional study included 40 preterm neonates divided into two groups: group I included 20 preterm neonates with suspected NEC according to Modified Bell Staging Criteria for NEC and group II included 20 preterm neonates with non-NEC. All the included participants underwent full history taking, full examination, routine laboratory investigations, and assessment of urinary iFABP. Results The mean urinary iFABP level was 17.26 ± 3.69 ng/dl in group I and 8.39 ± 2.49 ng/ml in group II. This difference was significantly higher in the suspected NEC group (P = 0.001). The iFABP level at a cutoff more than 9.25 ng/ml had significant power of discrimination of NEC cases at an early stage (P = 0.001) with a sensitivity of 96.0% and specificity of 71.0%. Linear regression revealed that the sampling time was a significant measure for prediction of iFABP (P = 0.001). Conclusion There was an association between elevated iFABP levels in urine and NEC, suggesting that iFABP may be useful as a diagnostic biomarker for earlier identification of NEC.
{"title":"Urine-based detection of intestinal mucosal cell damage in neonates with suspected necrotizing enterocolitis","authors":"Fady Elgendy, Nouran Aboelkhair, Nesma El-Desokyc, Hanan Z El-Sayed","doi":"10.4103/mmj.mmj_271_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_271_22","url":null,"abstract":"Objectives To assess the diagnostic value of the urinary intestinal fatty acid-binding protein (iFABP) in neonatal necrotizing enterocolitis (NEC) in the early stage of the disease. Background NEC is a severe acute gastrointestinal disease affecting preterm newborns. iFABP has been associated with injury to the intestinal mucosa common to NEC. Patients and methods This cross-sectional study included 40 preterm neonates divided into two groups: group I included 20 preterm neonates with suspected NEC according to Modified Bell Staging Criteria for NEC and group II included 20 preterm neonates with non-NEC. All the included participants underwent full history taking, full examination, routine laboratory investigations, and assessment of urinary iFABP. Results The mean urinary iFABP level was 17.26 ± 3.69 ng/dl in group I and 8.39 ± 2.49 ng/ml in group II. This difference was significantly higher in the suspected NEC group (P = 0.001). The iFABP level at a cutoff more than 9.25 ng/ml had significant power of discrimination of NEC cases at an early stage (P = 0.001) with a sensitivity of 96.0% and specificity of 71.0%. Linear regression revealed that the sampling time was a significant measure for prediction of iFABP (P = 0.001). Conclusion There was an association between elevated iFABP levels in urine and NEC, suggesting that iFABP may be useful as a diagnostic biomarker for earlier identification of NEC.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"6 1","pages":"1835 - 1840"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81034035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives To compare elective induction of labor at 39 weeks' gestational age in uncomplicated pregnancies with expectant management of up to 41 weeks' gestation and induction of labor in undelivered mothers. Background Late-term and postterm pregnancies are associated with increased maternal and fetal risks, thus several studies have considered induction of labor between 39 and 41 weeks' gestational age. Patients and methods This study was a randomized case–control study on 194 pregnant women at 39 weeks for labor induction at Menoufia University Hospitals and Elsalam Specialized Hospital during the period between December 2020 and June 2022. Results In the present study, there was highly statistically significant (P < 0.001) increased Apgar score at 5 min in group A (interquartile range = 8–9) when compared with group B (interquartile range = 8–8) and statistically significant (P = 0.048) increased birth weight in group B when compared with group A. The cesarean section rate was statistically significant (P = 0.005) in group B (39.1%) than in group A (20.6%). Conclusion Labor induction at 39 weeks should be offered to low-risk women. That policy is associated with fewer cesarean section and other complications. If woman chooses spontaneous labor onset she should have regular fetal monitoring as several studies have suggested increased risk of perinatal death by increasing gestational age.
{"title":"Impact of elective induction of labor at 39 weeks' gestational age on maternal and neonatal risk","authors":"I. Elnasr, M. Elsheikh, A. Elhalaby","doi":"10.4103/mmj.mmj_300_22","DOIUrl":"https://doi.org/10.4103/mmj.mmj_300_22","url":null,"abstract":"Objectives To compare elective induction of labor at 39 weeks' gestational age in uncomplicated pregnancies with expectant management of up to 41 weeks' gestation and induction of labor in undelivered mothers. Background Late-term and postterm pregnancies are associated with increased maternal and fetal risks, thus several studies have considered induction of labor between 39 and 41 weeks' gestational age. Patients and methods This study was a randomized case–control study on 194 pregnant women at 39 weeks for labor induction at Menoufia University Hospitals and Elsalam Specialized Hospital during the period between December 2020 and June 2022. Results In the present study, there was highly statistically significant (P < 0.001) increased Apgar score at 5 min in group A (interquartile range = 8–9) when compared with group B (interquartile range = 8–8) and statistically significant (P = 0.048) increased birth weight in group B when compared with group A. The cesarean section rate was statistically significant (P = 0.005) in group B (39.1%) than in group A (20.6%). Conclusion Labor induction at 39 weeks should be offered to low-risk women. That policy is associated with fewer cesarean section and other complications. If woman chooses spontaneous labor onset she should have regular fetal monitoring as several studies have suggested increased risk of perinatal death by increasing gestational age.","PeriodicalId":18558,"journal":{"name":"Menoufia Medical Journal","volume":"263 1","pages":"1970 - 1976"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84772783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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