Metabolic Encephalopathy (ME) is a group of diseases with central nervous system dysfunction caused by a variety of etiologies. According to the etiology, it can be divided into Wernicker's encephalopathy (WE) caused by thiamine deficiency, hepatic encephalopathy (HE) caused by liver dysfunction and eventual ammonia poisoning in patients with cirrhosis, hyponatremic encephalopathy caused by plasma hypotonic due to low serum sodium, uremic encephalopathy (UE) caused by toxin accumulation after renal dysfunction, and dysglycemic encephalopathy caused by excessive blood glucose fluctuation. The pathophysiological mechanism of ME is not the same, but for the clinical symptoms, it all show different degrees of neuro-mental symptoms. The mild manifestations are indifference, irritability, time-space sensory disorders, thinking retardation, mental decline etc., and the serious manifestations are delirium, lethargy, coma. In patients with existing metabolic encephalopathy, treating the disease is not an easy task for every clinician, but prevention of metabolic encephalopathy may be much simpler and the return greater than treatment.
{"title":"Metabolic Encephalopathy After Surgery Hepatobiliary and Pancreatic Diseases","authors":"","doi":"10.33140/mcr.08.08.10","DOIUrl":"https://doi.org/10.33140/mcr.08.08.10","url":null,"abstract":"Metabolic Encephalopathy (ME) is a group of diseases with central nervous system dysfunction caused by a variety of etiologies. According to the etiology, it can be divided into Wernicker's encephalopathy (WE) caused by thiamine deficiency, hepatic encephalopathy (HE) caused by liver dysfunction and eventual ammonia poisoning in patients with cirrhosis, hyponatremic encephalopathy caused by plasma hypotonic due to low serum sodium, uremic encephalopathy (UE) caused by toxin accumulation after renal dysfunction, and dysglycemic encephalopathy caused by excessive blood glucose fluctuation. The pathophysiological mechanism of ME is not the same, but for the clinical symptoms, it all show different degrees of neuro-mental symptoms. The mild manifestations are indifference, irritability, time-space sensory disorders, thinking retardation, mental decline etc., and the serious manifestations are delirium, lethargy, coma. In patients with existing metabolic encephalopathy, treating the disease is not an easy task for every clinician, but prevention of metabolic encephalopathy may be much simpler and the return greater than treatment.","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129114402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biophysics is searching for, dealing of and teaching the forms of the connections between the inanimate nature, the living world and the spiritual life, the applicability limits of their own laws in the other medium, their common mutual interactions. Biophysics undertakes, by means of mathematics, desc¬ription of the so-called homeostasis established by the dynamic equilibrium of the common normal state of the nature, the living world and that of the spirit. According to system theory, the human is a system, the five subsystems of which (digestive, respiratory, circulatory, exc¬retory, and reproductive) formed during phylogenetic develop¬ment short are addressed in this article. In living organisms, structure and function can be con¬sidered as a symbiosis: structure defines function, and function influences, modifies and develops the struc¬ture, which again enables a higher level function and activity. Many long-lasting structural perturbations result in func¬tional perturbations and similarly, long-lasting functional perturbations result in structural perturbations. This perturbation symbiosis is represented by the large group of psychological perturbations.
{"title":"The biophysical modelling of the human organism by the biophysical point of view","authors":"J. Vincze, Gabriella Vincze-Tiszay","doi":"10.33140/mcr.08.08.04","DOIUrl":"https://doi.org/10.33140/mcr.08.08.04","url":null,"abstract":"Biophysics is searching for, dealing of and teaching the forms of the connections between the inanimate nature, the living world and the spiritual life, the applicability limits of their own laws in the other medium, their common mutual interactions. Biophysics undertakes, by means of mathematics, desc¬ription of the so-called homeostasis established by the dynamic equilibrium of the common normal state of the nature, the living world and that of the spirit. According to system theory, the human is a system, the five subsystems of which (digestive, respiratory, circulatory, exc¬retory, and reproductive) formed during phylogenetic develop¬ment short are addressed in this article. In living organisms, structure and function can be con¬sidered as a symbiosis: structure defines function, and function influences, modifies and develops the struc¬ture, which again enables a higher level function and activity. Many long-lasting structural perturbations result in func¬tional perturbations and similarly, long-lasting functional perturbations result in structural perturbations. This perturbation symbiosis is represented by the large group of psychological perturbations.","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"66 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128835133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 59-years-old man, producing suckling oral sounds during several months, displayed a simultaneous brain stem aneurysm. The arterial lesion was submitted to embolization, but the buccal symptoms persisted after the manipulation. The nature of the bruit originating from the oral cavity remains void. A possible association between the two events, that from the buccal origin, as well as the brain stem aneurysmal defect, should perhaps be considered
{"title":"Serendipity-When Looking For His She-Donkeys, Young Saul Unveiled His Royalty","authors":"D. Benharroch","doi":"10.33140/mcr.08.08.09","DOIUrl":"https://doi.org/10.33140/mcr.08.08.09","url":null,"abstract":"A 59-years-old man, producing suckling oral sounds during several months, displayed a simultaneous brain stem aneurysm. The arterial lesion was submitted to embolization, but the buccal symptoms persisted after the manipulation. The nature of the bruit originating from the oral cavity remains void. A possible association between the two events, that from the buccal origin, as well as the brain stem aneurysmal defect, should perhaps be considered","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131882574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhat syndrome is a culture-bound syndrome originating from South Asia, characterized by a strong belief in the harmful effects of semen loss on health. The fear is fueled by the belief that the loss of semen leads to physical and psychological problems, including a perceived loss of sexual potency and vital energy. This research aims to explore the cultural beliefs and attitudes surrounding Dhat Syndrome and its impact on Asian American populations. The goal is to examine the cultural attitude towards the diagnosis and treatment options of semen loss.
{"title":"Unraveling Cultural Perceptions and Attitudes towards Dhat Syndrome in Asian American Communities: A Window into Diagnosis and Treatment Influences","authors":"Albert Starvin, Chiraag Ashokkumar, K. Dharmapuri","doi":"10.33140/mcr.08.08.08","DOIUrl":"https://doi.org/10.33140/mcr.08.08.08","url":null,"abstract":"Dhat syndrome is a culture-bound syndrome originating from South Asia, characterized by a strong belief in the harmful effects of semen loss on health. The fear is fueled by the belief that the loss of semen leads to physical and psychological problems, including a perceived loss of sexual potency and vital energy. This research aims to explore the cultural beliefs and attitudes surrounding Dhat Syndrome and its impact on Asian American populations. The goal is to examine the cultural attitude towards the diagnosis and treatment options of semen loss.","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126339706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Diabetes Mellitus has affected humans for many decades, and the descriptions of it are amazing important, which it's incidence is rising abruptly worldwide, Nowadays, the introduction of new insulin formulations and a new emphasis on tight blood glucose control make inpatient diabetes treatment has become more complicated, and it requires very careful monitoring by the nursing staff, while expanding their knowledge and practical skills to prevent dangerous side effects when giving insulin to patients. Objectives: The study aims to assess the nurse's knowledge and awareness regarding Insulin Therapy for Diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital, and finding the association between demographic data which as the gender, educational level, years of experiences in the emergency department, and training course and their level of nurse's knowledge. Materials and Methods: Descriptive study has been carried out to assess the nurse's knowledge and awareness regarding insulin therapy for diabetic patients in the emergency department at Al Diwaniyah Teaching Hospital for the period from 16 of January 2022 to 10 July of 2022. A purposive sample of (50) nurses who work in the emergency department at Al Diwaniyah Teaching Hospital. A questionnaire format was constructed to assess the knowledge of nurses about insulin therapy for diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital.The questionnaire was divide to two main parts: First Part: Demographic data of the sample include (Age, Gender, Educational level, Duration of work as a nurse, Years of experiences and training courses regarding management of diabetic patients and insulin therapy. Second Part: This part include 18 multiple questions to assess the knowledge of nurses and awareness about insulin therapy for diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital. Results: Results of the study shows the highest of nurses’ knowledge items are (Moderate). While (Bad) was the main nurses’ knowledge regarding to store insulin and perform a physical assessment to establish a baseline before beginning therapy. The majority of nurses 77.8% of nurses' knowledge have Moderate, while 11.1% of them have Bad and 11.1% of them have (Good) regarding to overall Assessment of nurses’ knowledge, there are a highly association between education level, and years of experience about management of diabetic Patients undergoing insulin therapy in the emergency department. Conclusion: The study concluded that the highest of nurses’ knowledge items are (Moderate). While (Bad) was the main nurses’ knowledge regarding to store insulin and perform a physical assessment to establish a baseline before beginning therapy. Also there are a highly association between level of education, and years of experience about insulin therapy for diabetic patients in the emergency department and their efficacy of nurses’ knowledge. Recommendations:
{"title":"Nurse's knowledge and awareness regarding insulin therapy for diabetic patients in the emergency department at al diwaniyah teaching hospital","authors":"","doi":"10.33140/mcr.08.08.03","DOIUrl":"https://doi.org/10.33140/mcr.08.08.03","url":null,"abstract":"Background: Diabetes Mellitus has affected humans for many decades, and the descriptions of it are amazing important, which it's incidence is rising abruptly worldwide, Nowadays, the introduction of new insulin formulations and a new emphasis on tight blood glucose control make inpatient diabetes treatment has become more complicated, and it requires very careful monitoring by the nursing staff, while expanding their knowledge and practical skills to prevent dangerous side effects when giving insulin to patients. Objectives: The study aims to assess the nurse's knowledge and awareness regarding Insulin Therapy for Diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital, and finding the association between demographic data which as the gender, educational level, years of experiences in the emergency department, and training course and their level of nurse's knowledge. Materials and Methods: Descriptive study has been carried out to assess the nurse's knowledge and awareness regarding insulin therapy for diabetic patients in the emergency department at Al Diwaniyah Teaching Hospital for the period from 16 of January 2022 to 10 July of 2022. A purposive sample of (50) nurses who work in the emergency department at Al Diwaniyah Teaching Hospital. A questionnaire format was constructed to assess the knowledge of nurses about insulin therapy for diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital.The questionnaire was divide to two main parts: First Part: Demographic data of the sample include (Age, Gender, Educational level, Duration of work as a nurse, Years of experiences and training courses regarding management of diabetic patients and insulin therapy. Second Part: This part include 18 multiple questions to assess the knowledge of nurses and awareness about insulin therapy for diabetic Patients in the emergency department at Al Diwaniyah Teaching Hospital. Results: Results of the study shows the highest of nurses’ knowledge items are (Moderate). While (Bad) was the main nurses’ knowledge regarding to store insulin and perform a physical assessment to establish a baseline before beginning therapy. The majority of nurses 77.8% of nurses' knowledge have Moderate, while 11.1% of them have Bad and 11.1% of them have (Good) regarding to overall Assessment of nurses’ knowledge, there are a highly association between education level, and years of experience about management of diabetic Patients undergoing insulin therapy in the emergency department. Conclusion: The study concluded that the highest of nurses’ knowledge items are (Moderate). While (Bad) was the main nurses’ knowledge regarding to store insulin and perform a physical assessment to establish a baseline before beginning therapy. Also there are a highly association between level of education, and years of experience about insulin therapy for diabetic patients in the emergency department and their efficacy of nurses’ knowledge. Recommendations:","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129445127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality during pregnancy or early after delivery and it remains a diagnostic and therapeutic challenge. The latest Confidential Enquiry into Maternal Deaths showed that VTE is now the third leading cause of direct maternal mortality, beside sepsis and hypertension. In particular the prevalence of VTE has been estimated to be 1 per 1000-2000 pregnancies. The risk of VTE is five times higher in a pregnant woman than in non-pregnant woman of similar age and postpartum VTE is more common than antepartum VTE. This review aimed to provide an update of whole current literature on VTE in pregnancy highlighting the most recent findings in diagnostic and therapeutic strategies, considering in detail risks and benefits of various techniques and drug classes, for both mother and fetus. Large trials of anticoagulants administration in pregnancy are lacking and recommendations are mainly based on case series and on expert opinions. Nonetheless, anticoagulants are believed to improve the outcome of pregnancy for women with current or previous VTE
{"title":"Venous Thromboembolism During Pregnancy","authors":"G. Gal","doi":"10.33140/mcr.08.08.02","DOIUrl":"https://doi.org/10.33140/mcr.08.08.02","url":null,"abstract":"Venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality during pregnancy or early after delivery and it remains a diagnostic and therapeutic challenge. The latest Confidential Enquiry into Maternal Deaths showed that VTE is now the third leading cause of direct maternal mortality, beside sepsis and hypertension. In particular the prevalence of VTE has been estimated to be 1 per 1000-2000 pregnancies. The risk of VTE is five times higher in a pregnant woman than in non-pregnant woman of similar age and postpartum VTE is more common than antepartum VTE. This review aimed to provide an update of whole current literature on VTE in pregnancy highlighting the most recent findings in diagnostic and therapeutic strategies, considering in detail risks and benefits of various techniques and drug classes, for both mother and fetus. Large trials of anticoagulants administration in pregnancy are lacking and recommendations are mainly based on case series and on expert opinions. Nonetheless, anticoagulants are believed to improve the outcome of pregnancy for women with current or previous VTE","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"13 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121238689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Emotions consist of patterns of physiological changes associated with behaviors. The urgency of putting them into action accompanied by emotional sensations that determine behavior and adaptive functions have guided the evolution of our brain. Emotions are also called "response frames" and their neuronal and hormonal control affects moral judgments and social behaviors. Historically, their expressions and recognitions have also been addressed to examine the nature of the sensations that accompany the different emotions [1]. With Multidisciplinary Team ABA, we have done two Tests on Emotions and Synesthesia in Google Tool and Video-EBT-CVS test to induce in a gradual state of hypnosis, patients properly evaluated and in the management of emotions during the Covid and post-pandemic Covid. With the aim of teaching him to recognize and manage emotions with a gradual induction to a pseudo-hypnopompic state to tell us spontaneous story of their memories that, with a meditative music, lets flow and induce first an initial induction of emotions and final recognition of their emotions and others. Clinical study: The dissemination of the Tool Emotional/Synesthesia Battery Test among adults and students at Italian schools is in an early stage, but the partial data received until now, with informed consensus, are only 19 in total and among these only 5 patients have, for health reasons that we specify in detail below, have agreed to perform the preliminary evaluation tests after the EBT/CVS Tool of 90 minutes maximum with the aim to complete the Video induction EBT-CVS with hypnosis and training to management/ treatment emotions for a total time of 1 hour 14 minutes and 40 seconds. Materials and Methods: The sample was taken after a presentation of the research made in collaboration between Private Medical Study and ASST Bergamo West/East with a total of patients who performed Tool Test on Emotions and Synesthesia. The study sample that performed Tool Test remotely with Quilgo, 19 patients performed the Tool in Google, among them 5 also performed the Test of emotions and hypnotic induction in video EBT-CVS program. Only the Video-Emotional induction/synesthetic test with evaluation of the 5 subjects, already known for years, evaluate their neuro-endocrinal and psychological pathology conditions, as described above, with 3 preliminary tests for stable their psycho-intellectual state of departure in sufficient well-being, the respective tests are: Mini Mental state examination (Italian) by MF Folstein, Raven’s standard Matrices, Test to evaluate the Hypnosis Induction Profile or Hypnotic Induction Profile of Spiegel (HIP), the Program with Tool Emotional/ Synesthesia Battery Test (EBT-CVS) and Video Test with Emotion Induction Test/Synesthesia Colombo-Vassallo-Shore or EBT-video CVS. Data analysis: The Google Test Tool EBT-CVS was sent to 44 patients in charge, of which 19 completed and sent within the 90 minutes required as the maximum time of p
{"title":"Emotional and Synesthetic Test of Hypnosis Induction with Video to relieve the patient from psycho-physical pain","authors":"","doi":"10.33140/mcr.08.08.01","DOIUrl":"https://doi.org/10.33140/mcr.08.08.01","url":null,"abstract":"Introduction: Emotions consist of patterns of physiological changes associated with behaviors. The urgency of putting them into action accompanied by emotional sensations that determine behavior and adaptive functions have guided the evolution of our brain. Emotions are also called \"response frames\" and their neuronal and hormonal control affects moral judgments and social behaviors. Historically, their expressions and recognitions have also been addressed to examine the nature of the sensations that accompany the different emotions [1]. With Multidisciplinary Team ABA, we have done two Tests on Emotions and Synesthesia in Google Tool and Video-EBT-CVS test to induce in a gradual state of hypnosis, patients properly evaluated and in the management of emotions during the Covid and post-pandemic Covid. With the aim of teaching him to recognize and manage emotions with a gradual induction to a pseudo-hypnopompic state to tell us spontaneous story of their memories that, with a meditative music, lets flow and induce first an initial induction of emotions and final recognition of their emotions and others. Clinical study: The dissemination of the Tool Emotional/Synesthesia Battery Test among adults and students at Italian schools is in an early stage, but the partial data received until now, with informed consensus, are only 19 in total and among these only 5 patients have, for health reasons that we specify in detail below, have agreed to perform the preliminary evaluation tests after the EBT/CVS Tool of 90 minutes maximum with the aim to complete the Video induction EBT-CVS with hypnosis and training to management/ treatment emotions for a total time of 1 hour 14 minutes and 40 seconds. Materials and Methods: The sample was taken after a presentation of the research made in collaboration between Private Medical Study and ASST Bergamo West/East with a total of patients who performed Tool Test on Emotions and Synesthesia. The study sample that performed Tool Test remotely with Quilgo, 19 patients performed the Tool in Google, among them 5 also performed the Test of emotions and hypnotic induction in video EBT-CVS program. Only the Video-Emotional induction/synesthetic test with evaluation of the 5 subjects, already known for years, evaluate their neuro-endocrinal and psychological pathology conditions, as described above, with 3 preliminary tests for stable their psycho-intellectual state of departure in sufficient well-being, the respective tests are: Mini Mental state examination (Italian) by MF Folstein, Raven’s standard Matrices, Test to evaluate the Hypnosis Induction Profile or Hypnotic Induction Profile of Spiegel (HIP), the Program with Tool Emotional/ Synesthesia Battery Test (EBT-CVS) and Video Test with Emotion Induction Test/Synesthesia Colombo-Vassallo-Shore or EBT-video CVS. Data analysis: The Google Test Tool EBT-CVS was sent to 44 patients in charge, of which 19 completed and sent within the 90 minutes required as the maximum time of p","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116343750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ming-Wei Yin, Ji Hua Ma, Gui Zhen Jiang, N. Zhao, Xue-jun Chen
Introduction: The adverse transfusion reactions (ATRs) underlying the developments of transfusion severely disturbed transfusion therapy, which should deserve more attention from technologists. Case Presentation: One bag of Fresh Frozen Plasma (FFP) was implicated in one case of anaphylactic shock in a pediatric rhabdomyosarcoma (RMS) patient. The plasma from a donor and the pre-/post-transfused plasma from the patient was used to evaluate the immunoglobulin (Ig) A, IgE by serum immunoglobulin assay, and interleukin (IL) 2, IL-4, IL-6, IL-10, TNF and IFN-γ by flow cytometry. The IgE concentration in the plasma from the pre-transfused patient was 1980 IU/mL, which indicates that the patient was in a hyperallergenic state prior to FFP transfusion, and with a history of anaphylactic reaction induced by plasma transfusion and that coupled with continuous stimulation of plasma components induced the occurrence of anaphylactic shock. The IgE level increased to 3160 IU/mL when the shock occurred. The IL-6 and IL-10 were elevated from 218.7 pg/mL before transfusion to 284.1 pg/mL after transfusion and from 4.2 pg/mL to 15.8 pg/mL. Conclusions: The high concentration of IgE in the patient with a history of allergy before transfusion can induce severe ATRs, leading to the occurrence of anaphylactic shock, and although rare, it should not be ignored. These patients need management that is more advanced and examinations before plasma transfusion and more inspections during the transfusion process.
{"title":"Fresh Frozen Plasma Transfusion Induced Anaphylactic Shock: A Case Report","authors":"Ming-Wei Yin, Ji Hua Ma, Gui Zhen Jiang, N. Zhao, Xue-jun Chen","doi":"10.33140/mcr.08.07.06","DOIUrl":"https://doi.org/10.33140/mcr.08.07.06","url":null,"abstract":"Introduction: The adverse transfusion reactions (ATRs) underlying the developments of transfusion severely disturbed transfusion therapy, which should deserve more attention from technologists. Case Presentation: One bag of Fresh Frozen Plasma (FFP) was implicated in one case of anaphylactic shock in a pediatric rhabdomyosarcoma (RMS) patient. The plasma from a donor and the pre-/post-transfused plasma from the patient was used to evaluate the immunoglobulin (Ig) A, IgE by serum immunoglobulin assay, and interleukin (IL) 2, IL-4, IL-6, IL-10, TNF and IFN-γ by flow cytometry. The IgE concentration in the plasma from the pre-transfused patient was 1980 IU/mL, which indicates that the patient was in a hyperallergenic state prior to FFP transfusion, and with a history of anaphylactic reaction induced by plasma transfusion and that coupled with continuous stimulation of plasma components induced the occurrence of anaphylactic shock. The IgE level increased to 3160 IU/mL when the shock occurred. The IL-6 and IL-10 were elevated from 218.7 pg/mL before transfusion to 284.1 pg/mL after transfusion and from 4.2 pg/mL to 15.8 pg/mL. Conclusions: The high concentration of IgE in the patient with a history of allergy before transfusion can induce severe ATRs, leading to the occurrence of anaphylactic shock, and although rare, it should not be ignored. These patients need management that is more advanced and examinations before plasma transfusion and more inspections during the transfusion process.","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131187229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Low-dose-rate brachytherapy (LDR-BT) is a an internal radiation therapy method for the treatment of localized prostate cancer The treatment modality has been known for several decades. The choice of the treatment modality for prostate cancer patients depends mainly on the stage of the disease and the prognostic factors. Brachytherapy monotherapy is a well-tolerated procedure compared to alternative treatments. Based on a literature review, we have considered a prospective study on the treatment efficiency after LDR-BT with a permanent iodine-125 (I-125) implant, compared to that of hypo-fractionated external beam radiotherapy (EBRT) alone. The working thesis is to present the advantages and disadvantages of LDR-BT for low-risk prostate carcinoma, compared to a similar group of patients treated with definitive intensity-modulated hypo-fractionated radiotherapy (IMHRT)
{"title":"Low-dose-rate brachytherapy in low-risk prostate cancer- treatment results, radiation toxicity and quality of life-dissertation project with literature review","authors":"","doi":"10.33140/mcr.08.07.02","DOIUrl":"https://doi.org/10.33140/mcr.08.07.02","url":null,"abstract":"Low-dose-rate brachytherapy (LDR-BT) is a an internal radiation therapy method for the treatment of localized prostate cancer The treatment modality has been known for several decades. The choice of the treatment modality for prostate cancer patients depends mainly on the stage of the disease and the prognostic factors. Brachytherapy monotherapy is a well-tolerated procedure compared to alternative treatments. Based on a literature review, we have considered a prospective study on the treatment efficiency after LDR-BT with a permanent iodine-125 (I-125) implant, compared to that of hypo-fractionated external beam radiotherapy (EBRT) alone. The working thesis is to present the advantages and disadvantages of LDR-BT for low-risk prostate carcinoma, compared to a similar group of patients treated with definitive intensity-modulated hypo-fractionated radiotherapy (IMHRT)","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120965734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In medicine we live the period of enthusiastic use of the models that use, one way or the other, various devices created and invented on the basis of theoretical knowledge of biophysics. Further on we will deal with only three directions: ultrasound application, computer tomography and magnetic resonance. Currently, the widest field of application of the ultrasounds in medicine is the one of exploration and diagnostic. The computer tomography (CT) used X rays to perform detailed images of the structures of the organism. A part of the scanner can be tilted, which allows taking images of the studied are in various positions. The images are memorized in a computer. The images of the computer tomography scanner can be taken before or after the administration of the contrast substance. With the MRI examination, very small lesions (1-2 mm) can be detected and there is the possibility of Multiplan representation. In the case of medical investigations using MRI, the body of the patient is placed on a horizontal table along a very strong magnetic field and with a coil another type of radiofrequency is used which subsequently is recorded. The first uncertainty relation: Living organism cannot be studied in the space, at any small or big dimensions because at the level of those subsystems or extrasystems the characteristics of life disappear. The second uncertainty relation: Living organisms cannot be studied in time, at any long or short intervals, because at the level of these time values the living system do not have the characteristics of life.
{"title":"The biophysical modelling of the medical devices in the field of biophysics","authors":"J. Vincze, Gabriella Vincze-Tiszay","doi":"10.33140/mcr.08.07.03","DOIUrl":"https://doi.org/10.33140/mcr.08.07.03","url":null,"abstract":"In medicine we live the period of enthusiastic use of the models that use, one way or the other, various devices created and invented on the basis of theoretical knowledge of biophysics. Further on we will deal with only three directions: ultrasound application, computer tomography and magnetic resonance. Currently, the widest field of application of the ultrasounds in medicine is the one of exploration and diagnostic. The computer tomography (CT) used X rays to perform detailed images of the structures of the organism. A part of the scanner can be tilted, which allows taking images of the studied are in various positions. The images are memorized in a computer. The images of the computer tomography scanner can be taken before or after the administration of the contrast substance. With the MRI examination, very small lesions (1-2 mm) can be detected and there is the possibility of Multiplan representation. In the case of medical investigations using MRI, the body of the patient is placed on a horizontal table along a very strong magnetic field and with a coil another type of radiofrequency is used which subsequently is recorded. The first uncertainty relation: Living organism cannot be studied in the space, at any small or big dimensions because at the level of those subsystems or extrasystems the characteristics of life disappear. The second uncertainty relation: Living organisms cannot be studied in time, at any long or short intervals, because at the level of these time values the living system do not have the characteristics of life.","PeriodicalId":186238,"journal":{"name":"Medical & Clinical Research","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116261943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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