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Patterns of Use and Barriers to STI Point-of-care Tests for Military Obstetrician Gynecologists. 军队妇产科医生使用性传播感染护理点检测的模式和障碍。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae283
Jill E Brown, Kayla M Hudson, Anne M Rompalo, Charlotte A Gaydos

Introduction: Sexually transmitted infections (STIs) are commonly reported in military populations. Point-of-care tests (POCTs) are commercially available, but their use is variable in the civilian sector. Their use among military providers has not been evaluated. We sought to identify the pattern of use and barriers to using STI POCTs for military obstetrician/gynecologists (OBGYNs).

Materials and methods: We adapted a survey of civilian OBGYNs on patterns of use and barriers to STI POCTs for military OBGYNs. We sent an online questionnaire to 479 military OBGYNs via Army, Air Force, and Navy specialty leaders in May 2023. The questionnaire included 14 demographic questions and up to 52 questions regarding availability, use, and barriers to STI POCTs. The USU Institutional Review Board deemed the study exempt from Institutional Review Board review.

Results: Of the 479 solicited, 117 participated in the survey (24.4%). Of respondents, 64.1% were women and 79.5% non-Hispanic white. Sexually transmitted infections were detected once to twice weekly by 13.0% of respondents and once or twice monthly by 52.8%. The most available STI-related POCTs were wet mount prep (68.7%), rapid HIV (43.3%), and urine dipstick (38.6%). Gram stain was available for 30.3%, the Affirm VPIII (Becton, Dickinson and Company, Franklin Lakes, NJ) for 24.5%, and stat RPR for 16.3%. Economic barriers to using POCTs included cost of the test from manufacturer/distributor (57.9%) and military funding/stocking decisions (10.3%). The greatest barriers to use were the purchasing of an instrument (60.8%) and the interruption to workflow in clinic (57.8%).

Conclusions: Military OBGYNs rely on several STI-related POCTs. Economic factors and interruption to workflow were cited as the most significant barriers to using POCTs for military OBGYNs. Test cost and impact on workflow should be considered in future development and procurement of POCTs for the Military Health System.

导言:性传播感染(STIs)在军队人群中很常见。护理点检测(POCT)可在市场上买到,但在民用领域的使用情况却不尽相同。目前尚未对其在军队提供者中的使用情况进行评估。我们试图确定军队妇产科医生(OBGYN)使用 STI POCT 的模式和障碍:我们改编了一项关于军队妇产科医生使用 STI POCT 的模式和障碍的民间妇产科医生调查。我们于 2023 年 5 月通过陆军、空军和海军专业负责人向 479 名军事妇产科医生发送了一份在线问卷。问卷包括 14 个人口统计学问题和多达 52 个有关 STI POCT 的可用性、使用情况和障碍的问题。美国南加州大学机构审查委员会认为该研究免于机构审查委员会审查:在征集到的 479 位受访者中,有 117 位(24.4%)参与了调查。在受访者中,64.1% 为女性,79.5% 为非西班牙裔白人。13.0%的受访者每周检测一到两次性传播感染,52.8%的受访者每月检测一到两次。最常见的性传播感染相关 POCT 是湿装片预处理(68.7%)、快速 HIV 检测(43.3%)和尿液浸量尺(38.6%)。有 30.3% 的人可使用革兰氏染色法,24.5% 的人可使用 Affirm VPIII(Becton, Dickinson and Company, Franklin Lakes, NJ),16.3% 的人可使用 stat RPR。使用 POCT 的经济障碍包括制造商/经销商提供的检测成本(57.9%)和军方的资金/库存决定(10.3%)。使用的最大障碍是购买仪器(60.8%)和中断临床工作流程(57.8%):结论:军队妇产科医生依赖多种与性传播感染相关的 POCT。经济因素和工作流程中断被认为是军队妇产科医生使用 POCT 的最大障碍。在未来为军事卫生系统开发和采购 POCTs 时,应考虑测试成本和对工作流程的影响。
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引用次数: 0
Efficacy of Polyunsaturated Fatty Acids as a Treatment for Post-traumatic Stress Disorder: A Systematic Review. 多不饱和脂肪酸治疗创伤后应激障碍的疗效:系统回顾。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae319
Kathryn A Capple, Elizabeth A Kostas-Polston, Mary B Engler, Choang Lai, Erika Sivarajan Froelicher

Introduction: Post-traumatic stress disorder (PTSD) is a prevalent health condition among members of the military. Although the efficacy of pharmacological and psychiatric interventions for PTSD has been well studied, there are limited data on the effects of omega-3 (n-3) polyunsaturated fatty acid (PUFA) interventions on PTSD. The use of PUFAs shows promise because of their neuroprotective effects. Thus, this systematic review will synthesize the current state of the evidence regarding the effectiveness of PUFA treatment for PTSD.

Materials and methods: Using the PubMed, PsychINFO, Embase, and CINAHL databases, a search of the literature was conducted using the search terms "posttraumatic-stress-disorder, combat disorders, trauma-related-stress-disorder, omega-3, fatty acid, and polyunsaturated fatty acids" to identify articles published from January 1, 2008, to January 1, 2024, that focused on PUFA interventions for PTSD. A total of 281 articles were identified. Following exclusions and quality assessments using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria proposed by Cochrane, 6 randomized controlled trials (RCTs) and preclinical studies were chosen for inclusion, and data were then extracted into a data matrix for final synthesis and analysis.

Results: The RCTs (n = 3) showed no significant effect of PUFAs in the prevention of PTSD symptom onset. Among preclinical studies (n = 3), PUFAs resulted in a significant decrease in anxiety-like behavior and fear memory and an increase in spatial learning and memory. The quality of evidence among the 6 RCTs and preclinical studies using the Cochrane GRADE criteria ranged from low to high.

Conclusions: The results from this systematic review suggest that more evidence is needed before making any recommendations for the clinical use of dietary PUFAs in the management of PTSD symptoms.

简介创伤后应激障碍(PTSD)是军人中普遍存在的一种健康问题。尽管对创伤后应激障碍的药物和精神干预的疗效进行了深入研究,但有关欧米伽-3(n-3)多不饱和脂肪酸(PUFA)干预对创伤后应激障碍的影响的数据却很有限。由于多不饱和脂肪酸具有神经保护作用,因此使用多不饱和脂肪酸大有可为。因此,本系统综述将综合目前有关 PUFA 治疗创伤后应激障碍有效性的证据:使用 PubMed、PsychINFO、Embase 和 CINAHL 数据库,以 "创伤后应激障碍、战斗障碍、创伤相关应激障碍、ω-3、脂肪酸和多不饱和脂肪酸 "为检索词进行文献检索,以确定从 2008 年 1 月 1 日至 2024 年 1 月 1 日期间发表的关注 PUFA 对创伤后应激障碍干预的文章。共鉴定出 281 篇文章。根据科克伦提出的建议评估、发展和评价分级(GRADE)标准进行排除和质量评估后,选择纳入了 6 项随机对照试验(RCT)和临床前研究,然后将数据提取到数据矩阵中进行最终综合和分析:结果:随机对照试验(3 项)显示,PUFA 在预防创伤后应激障碍症状发作方面没有明显效果。在临床前研究(3 项)中,PUFAs 可显著减少焦虑样行为和恐惧记忆,增加空间学习和记忆。根据 Cochrane GRADE 标准,6 项 RCT 和临床前研究的证据质量从低到高不等:本系统综述的结果表明,在临床上使用膳食中的 PUFAs 治疗创伤后应激障碍症状之前,还需要更多的证据。
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引用次数: 0
Addressing Differences in Knowledge and Experience in Trauma Care Capabilities Among an International Team of Military Medical Care Providers in a Deployed Setting. 解决国际军事医疗团队在部署环境中创伤护理能力方面的知识和经验差异。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae123
Sarah Holvelinsky, Taylor Travers, Joshua B Stierwalt, Paul Schunk, Brian Patrick Murray

Military medical personnel are crucial in providing life-saving care at the point of injury (POI) in challenging environments such as combat zones and disaster areas. This article examines the specialized training US Military medical personnel undergo before deployment and the increasing trend of deploying as part of multinational forces in operations like those in Afghanistan with NATO and non-NATO countries. Integrating medical teams from diverse backgrounds poses significant challenges in maintaining a cohesive and efficient team due to varying trauma management training standards and medical practices among the allied forces. Tactical Combat Casualty Care (TCCC) training and the development of clinical practice guidelines (CPG) by the US Joint Trauma Service have been key strategies by the US Military to standardize care. However, the variation in trauma management training among NATO allies and the differences in medical subspecialties and approaches can lead to inefficiencies and reduced effectiveness in a multinational trauma center setting. For instance, the approach to trauma care can significantly differ between the US and European countries, impacting the interoperability and teamwork in multinational medical teams. To address these challenges, the article highlights the importance of standardized medical training programs that include cultural awareness to enhance the effectiveness of multidisciplinary, multinational medical teams. It also underscores the necessity for standardized international trauma training in the face of increasing global conflicts and the potential for large-scale combat operations. The article discusses the "Trauma Tuesday" program implemented in Kabul, Afghanistan, as an example of how intensive training and simulation exercises can improve team dynamics, knowledge, and skills in trauma management among a diverse team from various nations. The need for ongoing education and developing a standard for managing trauma patients in international teams is emphasized to ensure effective communication and coordination. The article suggests that multinational trauma training can significantly improve team cohesion and critical life-saving skills, essential for future battlefields where access to definitive care may be delayed. Further research is recommended to explore the best methods for achieving effective multinational medical team integration and training standardization.

在战区和灾区等充满挑战的环境中,军事医疗人员在受伤点 (POI) 提供救生护理至关重要。本文探讨了美军医疗人员在部署前所接受的专门培训,以及在阿富汗等地与北约和非北约国家的行动中作为多国部队的一部分进行部署这一日益明显的趋势。由于盟军的创伤管理培训标准和医疗实践各不相同,整合来自不同背景的医疗团队对保持团队的凝聚力和效率提出了巨大挑战。战术战斗伤员救护(TCCC)培训和美国联合创伤服务部制定的临床实践指南(CPG)是美军实现救护标准化的关键策略。然而,北约盟国之间在创伤管理培训方面的差异以及医疗亚专业和方法上的差异可能会导致多国创伤中心的效率低下和效果降低。例如,美国和欧洲国家之间的创伤护理方法可能存在很大差异,从而影响多国医疗团队的互操作性和团队合作。为了应对这些挑战,文章强调了包括文化意识在内的标准化医疗培训计划的重要性,以提高多学科、多国医疗团队的效率。文章还强调,面对日益加剧的全球冲突和潜在的大规模作战行动,有必要开展标准化的国际创伤培训。文章讨论了在阿富汗喀布尔实施的 "创伤星期二 "计划,以此为例说明强化训练和模拟演习如何在来自不同国家的多元化团队中提高团队活力、知识和创伤管理技能。文章强调了持续教育和制定国际团队创伤患者管理标准的必要性,以确保有效的沟通和协调。文章认为,多国创伤培训可以极大地提高团队凝聚力和关键的救生技能,这对未来战场上可能会延迟获得最终救治的情况至关重要。建议开展进一步研究,探索实现多国医疗团队有效整合和培训标准化的最佳方法。
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引用次数: 0
A Case of Multidrug-Resistant Tuberculosis in an Active Duty Military Health Care Worker. 一名现役军人医护人员的耐多药结核病例。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae104
Amanda E Saunders, Kevin M Shanahan, John W Downs

Cases of active tuberculosis (TB) in the U.S. Military have fallen over the last century in large part due to improved screening and treatment options. The subset of multidrug-resistant TB (MDR-TB) is almost nonexistent within the U.S. Military. We present a case of MDR-TB in an active duty U.S. Military health care worker and discuss several considerations for treatment that may present challenges for U.S. Military medical practitioners. A 30-year-old active duty Soldier was referred to Army public health services after a bronchoscopy sample was positive for Mycobacterium tuberculosis complex. Sputum smears were negative for acid-fast bacilli, suggesting lower risk for community spread. One month after initiation of the standard 4-drug regimen for active TB, genetic susceptibility testing found the patient's M. tuberculosis isolate to be resistant to rifampin, isoniazid, and pyrazinamide. Contact investigation efforts among co-workers and family members fortunately found no new interferon-gamma release assay conversions. Coordination of public health assets to ensure a successful treatment regimen occurred across varied local, state, and federal agencies. Atypical medications required coordination with the FDA for procurement. An extensive surveillance plan for medication adverse effects was required. Finally, questions of public health authority versus patient autonomy arose requiring multidisciplinary input and ethical discussions.

上个世纪,美国军队中的活动性肺结核(TB)病例有所下降,这在很大程度上归功于筛查和治疗方法的改进。耐多药结核病(MDR-TB)在美军中几乎不存在。我们介绍了一例美军现役医护人员的 MDR-TB 病例,并讨论了可能给美军医疗从业人员带来挑战的治疗注意事项。一名 30 岁的现役士兵在支气管镜检查样本中发现复合结核分枝杆菌呈阳性后被转诊至军队公共卫生服务部门。痰涂片检查结果为阴性,这表明该病在社区传播的风险较低。在开始使用标准的四药治疗方案治疗活动性肺结核一个月后,基因药敏测试发现患者的结核分枝杆菌对利福平、异烟肼和吡嗪酰胺具有耐药性。幸运的是,在同事和家庭成员中开展的接触调查工作没有发现新的干扰素-γ 释放测定转换。为确保治疗方案取得成功,地方、州和联邦机构协调了公共卫生资源。非典型药物的采购需要与美国食品和药物管理局协调。还需要制定广泛的药物不良反应监测计划。最后,还出现了公共卫生权威与病人自主权的问题,需要多学科的投入和伦理讨论。
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引用次数: 0
Letter From the Chief Executive Officer Dr. John Cho. 首席执行官 John Cho 博士的信。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae519
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引用次数: 0
Pilot Study: Developing Curriculum to Prepare Fourth-Year Medical Students Applying for OBGYN Residency Within the Defense Health Agency. 试点研究:开发课程,为申请国防卫生局妇产科住院医师培训的四年级医学生做好准备。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae224
Danielle Wright, David Boedeker, Alexander Ulfers, Logan Peterson

Background: Obstetrics and gynecology (OBGYN) is becoming increasingly competitive among medical specialties. As a result, many medical schools have frameworks to help their students increase their competitiveness to maximize chances of a successful match. However, "boot camps" have traditionally been geared toward the transition to intern year and not to sub-internships during the fourth year of medical school. We aimed to develop a boot camp for rising fourth-year medical students planning to apply into OBGYN before the initiation of their sub-internships and interview season.

Methods: Sixteen students enrolled in this course led by faculty OBGYNs at our institution. We utilized a combination of mentorship, coaching, and education to achieve applicant success. The curriculum included formal lectures, surgical skills training, and focused feedback from our applicant development committee.

Results: Our response rate was 100% and 94% for the pre-intervention and post-intervention survey, respectively. Before the intervention, the majority of participants felt either neutral (47.4%) or unprepared (21.1%) regarding their knowledge before their sub-internships. However, after the intervention, all reported feeling more prepared for their rotations. All respondents either agreed (60%) or strongly agreed (40%) that the course increased their confidence in performing well on audition rotations. Our match rate increased from 62% for the class of 2022 (before this intervention) to 75% for the class of 2023.

Discussion: In light of the increasing residency match competitiveness, it is crucial to investigate programs that can assist students in developing stronger applications. This reproducible intervention utilizes few resources and can be implemented at most medical schools to better support their OBGYN applicants.

背景:妇产科(OBGYN)在医学专业中的竞争日趋激烈。因此,许多医学院都制定了框架,帮助学生提高竞争力,最大限度地增加成功匹配的机会。然而,"新兵训练营 "传统上都是针对向实习生年级过渡的,而不是针对医学院四年级的副实习生。我们的目标是在副实习和面试季开始之前,为计划申请妇产科的四年级医学生开设一个新兵训练营:方法:16 名学生参加了由本院妇产科教师主持的这一课程。我们将导师指导、辅导和教育相结合,以取得申请者的成功。课程包括正式讲座、手术技能培训以及申请人发展委员会的重点反馈:干预前和干预后调查的回复率分别为 100%和 94%。在干预前,大多数参与者对自己在实习前所掌握的知识持中立态度(47.4%)或毫无准备(21.1%)。然而,干预结束后,所有受访者都表示对轮岗实习有了更充分的准备。所有受访者都同意(60%)或非常同意(40%)该课程增强了他们在试听轮岗中表现出色的信心。我们的匹配率从 2022 届学生(干预前)的 62% 提高到了 2023 届学生的 75%:讨论:鉴于住院医师配对竞争日益激烈,研究能帮助学生开发更强申请能力的项目至关重要。这种可重复的干预措施只需少量资源,可在大多数医学院校实施,以更好地支持妇产科申请者。
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引用次数: 0
Balance, Landing Biomechanics, and Functional Movement Screen Characteristics With and Without Knee Exoskeleton in Military Soldiers. 军人使用和不使用膝部外骨骼时的平衡、着地生物力学和功能性运动筛查特征。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae285
Takashi Nagai, David J Zeppetelli, Lucas C Sarantos, Caleb D Johnson, Charles Joseph B Borden, Cole A Dempsey, Vanessa Ramirez

Introduction: A light-weight pneumatic-powered knee exoskeleton could augment mobility and lifting capabilities for a variety of occupational settings. However, added weight/bulkiness and artificially produced knee extension torque could compromise sensorimotor characteristics.

Materials and methods: Ten healthy participants conducted 3 visits within 10 days to the biomechanics laboratory. Participants were asked to complete the following tasks on each visit: single-leg balance, single-leg drop-landing, and select functional movement tasks. Balance characteristics (the ground reaction forces variability and center-of-pressure velocity) were derived from force plates while knee flexion angles during drop-landing and functional movement tasks were captured using a motion capture system. Descriptive statistics as well as paired t-tests or Wilcoxon signed-rank tests were used to compare between conditions. Significance was set at P < .05 a priori.

Results: During single-leg balance, the ground reaction force variabilities were significantly increased (P = .013-.019) and the center of pressure velocity was decreased (P = .001-.017) when wearing knee exoskeleton. During single-leg drop-landing, the exoskeleton condition showed lower knee flexion angles at the initial contact (P = .004-.021) and peak (P = .006-.010). Additionally, the peak vertical ground reaction force was higher in the exoskeleton condition (P = .007). During functional movement tasks, the exoskeleton condition showed less knee flexion range-of-motion during the overhead squat (P = .007-.033) and hurdle step-over (P = .004-.005).

Conclusions: Participants exhibited stiffer landing technique with the exoskeleton. Given that these compromised sensorimotor characteristics have been associated with musculoskeletal injury risk, modifications to exoskeletons to promote softer landing and greater knee flexion range-of-motion during dynamic activities may be warranted.

简介:轻型气动膝关节外骨骼可以增强各种职业环境下的移动和举重能力。然而,增加的重量/体积和人为产生的膝关节伸展扭矩可能会损害传感器运动特性:十名健康参与者在十天内三次访问生物力学实验室。每次访问都要求参与者完成以下任务:单腿平衡、单腿落地和选择功能性运动任务。平衡特性(地面反作用力变化率和压力中心速度)由测力板得出,而在完成落地和功能性运动任务时的膝关节屈曲角度则由运动捕捉系统捕捉。描述性统计以及配对 t 检验或 Wilcoxon 符号秩检验用于比较不同条件之间的差异。显著性设定为 P 结果:在单腿平衡过程中,穿戴膝外骨骼后,地面反作用力变异性显著增加(P = .013-.019),压力中心速度降低(P = .001-.017)。在单腿落地过程中,外骨骼条件显示出较低的膝关节屈曲角度,包括初始接触角度(P = .004-.021)和峰值角度(P = .006-.010)。此外,外骨骼状态下的垂直地面反作用力峰值更高(P = .007)。在功能性运动任务中,外骨骼状态下的学员在高抬腿深蹲(P = .007-.033)和跨栏(P = .004-.005)时膝关节屈曲运动幅度较小:结论:穿戴外骨骼后,参与者的着地技术更加僵硬。鉴于这些受损的感知运动特征与肌肉骨骼损伤风险有关,可能有必要对外骨骼进行修改,以促进在动态活动中更柔和的着地和更大的膝关节屈曲活动范围。
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引用次数: 0
Estimating Brain Injury Risk from Shipborne Underwater Blasts Using a High-fidelity Finite Element Head Model. 使用高保真有限元头部模型估算船载水下爆炸的脑损伤风险。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae309
Sushan Nakarmi, Yaohui Wang, Alice Lux Fawzi, Christian Franck, Rika Wright Carlsen
<p><strong>Introduction: </strong>Assessing the survivability of, and potential injury to, a ship's crew from underwater blast is crucial to understanding the operating capability of a military vessel following blast exposure. One form of injury that can occur and affect a crew member's ability to perform tasks is traumatic brain injury (TBI). To evaluate the risk of TBI from underwater blasts, injury metrics based on linear head acceleration have traditionally been used. Although these metrics are popular given their ease of use, they do not provide a direct measure of the tissue-level biomechanical responses that have been shown to cause neuronal injury. Tissue-based metrics of injury, on the other hand, may provide more insight into the potential risk of brain injury. Therefore, in this study, we assess the risk of TBI from underwater blasts using tissue-based measures of injury, such as tissue strain, strain rate, and intracranial pressure, in addition to the more commonly used head acceleration-based injury metrics.</p><p><strong>Materials and methods: </strong>A series of computational simulations were performed using a detailed finite element (FE) head model to study how inertial loading of the head from underwater blast events translates to potential injury in the brain. The head kinematics loading conditions for the simulations were obtained directly from Floating Shock Platform (FSP) tests where 3 Anthropomorphic Test Devices (ATDs) were positioned at 3 shipboard locations (desk, bulkhead, and bench), and the head acceleration was directly measured. The effect of the position and orientation of the ATDs and the distance of the underwater blast from the FSP (20-50 ft) on the risk of brain injury were assessed from the FE analysis.</p><p><strong>Results: </strong>The head accelerations and estimated TBI risk from the underwater blasts highly depend on the positioning of the ATDs on the FSP and decrease in severity as the charge standoff distance is increased. The ATD that was seated at a desk had the largest peak linear head acceleration (77.5 g) and negative intracranial pressure (-51.8 kPa). In contrast, the ATD that was standing at a bulkhead had the largest computed 95th percentile maximum principal strain (19%) and strain rate (25 s-1) in the brain. For all tested conditions, none of the ATDs exceeded the Head Injury Criterion (HIC-15) threshold of 700 for serious or fatal brain injury; however, the predicted tissue strains of the bulkhead ATD at the 20-ft charge standoff distance were within the range of proposed strain thresholds for a 50% risk of concussive injury, which illustrates the added value of considering tissue-level measures in addition to head acceleration when evaluating brain injury risk.</p><p><strong>Conclusions: </strong>In this work, we assessed the risk of brain injury from underwater blasts using an anatomically detailed subject-specific FE head model. Accurate assessment of the risk of TBI from underwater explo
简介:评估船员在水下爆炸中的生存能力和可能受到的伤害,对于了解军用船只在爆炸后的运行能力至关重要。一种可能发生并影响船员执行任务能力的伤害形式是创伤性脑损伤(TBI)。为了评估水下爆炸造成创伤性脑损伤的风险,传统上使用基于头部线性加速度的伤害指标。虽然这些指标因其易于使用而广受欢迎,但它们并不能直接测量组织层面的生物力学反应,而这些反应已被证明会导致神经元损伤。另一方面,以组织为基础的损伤指标可能会让人更深入地了解脑损伤的潜在风险。因此,在本研究中,除了更常用的基于头部加速度的损伤指标外,我们还使用了基于组织的损伤指标,如组织应变、应变率和颅内压,来评估水下爆炸造成创伤性脑损伤的风险:使用详细的有限元(FE)头部模型进行了一系列计算模拟,以研究水下爆炸事件对头部的惯性加载如何转化为对大脑的潜在伤害。模拟中的头部运动学加载条件直接从浮动冲击平台(FSP)测试中获得,在浮动冲击平台测试中,3 个拟人测试装置(ATD)被放置在船上的 3 个位置(桌子、舱壁和长凳),头部加速度被直接测量。通过有限元分析评估了 ATD 的位置和方向以及水下爆炸与 FSP 的距离(20-50 英尺)对脑损伤风险的影响:结果:水下爆炸的头部加速度和估计的创伤性脑损伤风险在很大程度上取决于 ATD 在 FSP 上的位置,并且随着装药距离的增加,其严重程度也会降低。坐在办公桌前的 ATD 的头部线性加速度峰值(77.5 g)和颅内负压(-51.8 kPa)最大。相比之下,站在隔板前的 ATD 脑部计算出的第 95 百分位数最大主应变(19%)和应变率(25 s-1)最大。在所有测试条件下,没有一个 ATD 超过头部伤害标准 (HIC-15) 700 的严重或致命脑损伤阈值;但是,隔板 ATD 在 20 英尺装药距离处的预测组织应变在脑震荡损伤风险为 50%的拟议应变阈值范围内,这说明在评估脑损伤风险时,除了头部加速度外,考虑组织级测量的附加价值:在这项工作中,我们使用解剖学上详细的特定受试者 FE 头部模型评估了水下爆炸造成脑损伤的风险。准确评估水下爆炸造成脑损伤的风险对于评估水下爆炸事件对船员造成的潜在伤害风险以及指导未来伤害缓解策略的制定以维护军舰上船员的安全非常重要。
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引用次数: 0
Medical Training Falls Short at Army Combat Training Centers. 陆军战斗训练中心的医疗培训不足。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae399
Brandon M Carius, Scott Szymanski, John Curtin, Matthew Lavoie, Aaron Alindogan
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引用次数: 0
Identifying and Reducing Insulin Errors in the Simulated Military Critical Care Air Transport Environment: A Human Factors Approach. 在模拟军事重症空运环境中识别和减少胰岛素错误:人为因素方法。
IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-16 DOI: 10.1093/milmed/usae286
Lane L Frasier, Mark Cheney, Joshua Burkhardt, Mark Alderman, Eric Nelson, Melissa Proctor, Daniel Brown, William T Davis, Maia P Smith, Richard Strilka
<p><strong>Introduction: </strong>During high-fidelity simulations in the Critical Care Air Transport (CCAT) Advanced course, we identified a high frequency of insulin medication errors and sought strategies to reduce them using a human factors approach.</p><p><strong>Materials and methods: </strong>Of 169 eligible CCAT simulations, 22 were randomly selected for retrospective audio-video review to establish a baseline frequency of insulin medication errors. Using the Human Factors Analysis Classification System, dosing errors, defined as a physician ordering an inappropriate dose, were categorized as decision-based; administration errors, defined as a clinician preparing and administering a dose different than ordered, were categorized as skill-based. Next, 3 a priori interventions were developed to decrease the frequency of insulin medication errors, and these were grouped into 2 study arms. Arm 1 included a didactic session reviewing a sliding-scale insulin (SSI) dosing protocol and a hands-on exercise requiring all CCAT teams to practice preparing 10 units of insulin including a 2-person check. Arm 2 contained arm 1 interventions and added an SSI cognitive aid available to students during simulation. Frequency and type of insulin medication errors were collected for both arms with 93 simulations for arm 1 (January-August 2021) and 139 for arm 2 (August 2021-July 2022). The frequency of decision-based and skill-based errors was compared across control and intervention arms.</p><p><strong>Results: </strong>Baseline insulin medication error rates were as follows: decision-based error occurred in 6/22 (27.3%) simulations and skill-based error occurred in 6/22 (27.3%). Five of the 6 skill-based errors resulted in administration of a 10-fold higher dose than ordered. The post-intervention decision-based error rates were 9/93 (9.7%) and 23/139 (2.2%), respectively, for arms 1 and 2. Compared to baseline error rates, both arm 1 (P = .04) and arm 2 (P < .001) had a significantly lower rate of decision-based errors. Additionally, arm 2 had a significantly lower decision-based error rate compared to arm 1 (P = .015). For skill-based preparation errors, 1/93 (1.1%) occurred in arm 1 and 4/139 (2.9%) occurred in arm 2. Compared to baseline, this represents a significant decrease in skill-based error in both arm 1 (P < .001) and arm 2 (P < .001). There were no significant differences in skill-based error between arms 1 and 2.</p><p><strong>Conclusions: </strong>This study demonstrates the value of descriptive error analysis during high-fidelity simulation using audio-video review and effective risk mitigation using training and cognitive aids to reduce medication errors in CCAT. As demonstrated by post-intervention observations, a human factors approach successfully reduced decision-based error by using didactic training and cognitive aids and reduced skill-based error using hands-on training. We recommend the development of a Clinical Practice Guideline in
简介:在重症监护空中转运(CCAT)高级课程的高仿真模拟中,我们发现胰岛素用药失误的频率很高,并寻求使用人为因素方法减少失误的策略:在 169 个符合条件的 CCAT 模拟中,随机抽取了 22 个进行回顾性音频视频审查,以确定胰岛素用药错误的基线频率。利用人为因素分析分类系统,将剂量错误(定义为医生下达了不适当的剂量)归类为决策型错误;将给药错误(定义为临床医生准备和给药的剂量与医嘱不同)归类为技能型错误。接下来,为减少胰岛素用药错误的发生频率,我们制定了 3 项先验干预措施,并将其分为 2 个研究臂。研究臂 1 包括一个回顾滑动量表胰岛素 (SSI) 给药方案的说教课程和一个实践练习,要求所有 CCAT 小组练习准备 10 单位的胰岛素,包括双人检查。第二组包含第一组的干预措施,并增加了一个 SSI 认知辅助工具,供学生在模拟过程中使用。两组均收集了胰岛素用药错误的频率和类型,其中第一组(2021 年 1 月至 8 月)93 次,第二组(2021 年 8 月至 2022 年 7 月)139 次。比较了对照组和干预组中决策性错误和技能性错误的发生频率:基线胰岛素用药错误率如下:6/22(27.3%)次模拟发生了决策性错误,6/22(27.3%)次发生了技能性错误。在 6 次技能错误中,有 5 次导致给药剂量比医嘱高出 10 倍。干预后,第一组和第二组基于决策的错误率分别为 9/93(9.7%)和 23/139(2.2%)。与基线错误率相比,干预组 1(P = .04)和干预组 2(P 结论:干预组 1 和干预组 2 的错误率均低于基线错误率:这项研究证明了在高仿真模拟过程中利用音频视频回顾进行描述性错误分析以及利用培训和认知辅助工具有效降低风险的价值,从而减少 CCAT 中的用药错误。干预后的观察结果表明,人为因素方法通过使用说教式培训和认知辅助工具成功地减少了决策性错误,并通过动手培训减少了技能性错误。我们建议制定临床实践指南,其中包括 SSI 协议、双人检查指南和认知辅助工具,以便在已部署的 CCAT 团队中实施。此外,应将胰岛素准备和给药的实践培训纳入家庭站持续培训,以减少行动环境中的用药错误。
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Military Medicine
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