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Healthy Eating Scores Are Positively Associated With Physical Fitness in Military Personnel. 军人健康饮食得分与体质呈正相关。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usag029
Jillian T Robillard, Bridget A Owens, Julie L McNiff, Lee M Margolis, James Philip Karl, Julianna M Jayne

Introduction: Diet quality, as measured by the Healthy Eating Index, is positively associated with physical performance and fitness in elite U.S. Army Soldiers. Whether the Healthy Eating Score (HES-7), which was recently developed as an expedient proxy for determining adherence to dietary guidelines among military personnel, is also associated with physical fitness is unclear. The objective of this study was to determine the association between HES-7, eating style, physical activity, and physical fitness as measured by the Army Combat Fitness Test (ACFT) among U.S. Army Soldiers.

Materials and methods: In this cross-sectional observational study, 483 active duty Soldiers and Cadets (75% enlisted, 87% male, 26 ± 6 years) from three Army installations completed the Military Eating Behavior Survey (MEBS). Healthy Eating Score-7 (range: 0-35), 6-event ACFT (range: 0-600), eating style, and physical activity were determined from MEBS responses. Physical fitness was defined as the aggregate score from all ACFT events, which collectively assess both aerobic and anaerobic fitness.

Results: The average ACFT score and HES-7 were 496 ± 61 and 18 ± 5, respectively. In a multivariate-adjusted linear regression model, each one-point increase in HES-7 was associated with a 2-point increase in ACFT score (P < .001). Compared to those with the highest quartile of HES-7 (23-34), those in the two lowest quartiles (HES-7: first quartile = 0-14, second quartile = 15-18), reported 30 (P < .001) and 19 point (P = .004) lower ACFT scores, respectively. High protein eating style was significantly associated with a 16 point (P = .01) increase in ACFT score and a balanced diet or high protein diet was associated with a 4-point higher HES-7 (P < .05) compared to those who reported -following no specific style.

Conclusions: A higher HES-7 and a high protein eating style were positively associated with physical fitness in this sample of Soldiers. Findings support the potential importance of diet quality and specific eating styles in physical performance of military service members.

通过健康饮食指数测量的饮食质量与美国陆军精英士兵的身体表现和健康呈正相关。健康饮食评分(HES-7)是最近发展起来的一种权宜代理,用于确定军事人员是否遵守饮食指南,是否也与身体健康有关尚不清楚。本研究的目的是确定美国陆军士兵的hs -7、饮食方式、身体活动和身体健康(通过陆军战斗健康测试(ACFT)测量)之间的关系。材料与方法:在本横断面观察研究中,来自三个陆军基地的483名现役士兵和学员(75%为士兵,87%为男性,26±6岁)完成了军人饮食行为调查(MEBS)。健康饮食评分-7(范围:0-35)、6项ACFT(范围:0-600)、饮食方式和身体活动从MEBS反应中确定。身体健康被定义为所有ACFT事件的总得分,这些事件共同评估有氧和无氧健康。结果:ACFT评分和HES-7评分平均分别为496±61分和18±5分。在多元调整的线性回归模型中,hs -7每增加1分,ACFT评分增加2分(P)。结论:在该样本中,较高的hs -7和高蛋白饮食方式与身体健康呈正相关。研究结果支持了饮食质量和特定饮食方式对军人身体表现的潜在重要性。
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引用次数: 0
Evaluating Pharmacogenomic Prescription Data in the Military Health System. 评估军队卫生系统药物基因组处方数据。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usaf652
Rachel Zigler, Austin Pagani, Mark Haigney, Taylor Berninger, Lydia Hellwig
<p><strong>Introduction: </strong>Pharmacogenomic testing (PGx) is often completed after an adverse drug event (ADE) has occurred, but moving toward a preemptive rather than reactive testing approach could potentially decrease preventable drug-related hospitalizations and positively impact combat readiness. Although prior research has suggested that PGx testing may aid in individual patient medical management, there is limited research assessing the potential impact of preemptive PGx testing in the Military Health System (MHS). In this study, we utilized MHS prescription data along with available genotypic and phenotypic population frequency data to estimate the potential impact of PGx testing in the diverse MHS patient population.</p><p><strong>Materials and methods: </strong>A retrospective cross-sectional study was conducted using fiscal year 2021 (FY21) prescription data from the Defense Health Agency (DHA) Pharmacy Operations Division. Medications that had Clinical Pharmacogenetics Implementation Consortium (CPIC) level A, A/B, and B designations prescribed to Active Duty, Reserve, Retired, and Dependent MHS beneficiaries ages 18 and up were included in the analyses. We evaluated the prescription count along with the age, biological sex, and MHS beneficiary status for medications prescribed within the MHS. We then estimated the number of MHS beneficiaries predicted to have non-normal metabolism of a given PGx-related medication. This data was presented as a range based on the CPIC allele and metabolizer frequency data which varies across PharmGKB-defined biogeographical groups. This study was approved and was determined exempt by the Uniformed Services University of Health Sciences (USUHS) and the Augustana University institutional review boards.</p><p><strong>Results: </strong>There were over 8 million unique prescriptions for 83 PGx-related medications with CPIC level A, A/B, or B designation in FY21. Of these, over 1.2 million prescriptions (15%) were for Active Duty and Reserve members, with the top 5 prescribed PGx-related medications for Active Duty members being ibuprofen, ondansetron, hydrocodone, omeprazole, and meloxicam. This study further analyzed 64 medications with known metabolism frequency data. In FY21, there were up to 632,974 MHS beneficiaries taking omeprazole who were predicted to have non-normal CYP2C19 metabolism, which represents the medication with the highest number of prescriptions among individuals with estimated non-normal metabolism. Among medications with a risk for severe ADE, allopurinol was at the top with up to 301 prescriptions provided to Active Duty members estimated to have the *58:01 variant, which is associated with increased risk for toxic epidermal necrolysis.</p><p><strong>Conclusions: </strong>Currently, PGx testing is an underutilized resource in the MHS system, despite the many PGx-related medications that are widely prescribed among all MHS beneficiaries who have actionable CPIC guidelines. Bas
药物基因组学检测(PGx)通常在药物不良事件(ADE)发生后完成,但采用先发制人而非被动检测方法可能会减少可预防的药物相关住院治疗,并对战备状态产生积极影响。尽管先前的研究表明,PGx检测可能有助于个体患者的医疗管理,但评估先发制人的PGx检测在军事卫生系统(MHS)中的潜在影响的研究有限。在这项研究中,我们利用MHS处方数据以及现有的基因型和表型群体频率数据来估计PGx检测在不同MHS患者群体中的潜在影响。材料和方法:采用国防卫生局(DHA)药房运营部门的2021财年(FY21)处方数据进行回顾性横断面研究。临床药物遗传学实施联盟(CPIC)规定的A级、A/B级和B级指定的药物适用于18岁及以上的现役、预备役、退休和受抚养MHS受益人。我们评估了处方数量以及年龄、生理性别和MHS内处方药物的MHS受益人状态。然后,我们估计了MHS受益人对给定的pgx相关药物代谢异常的人数。该数据是基于CPIC等位基因和代谢物频率数据的范围,这些数据在不同的pharmgkb定义的生物地理群体中有所不同。这项研究被卫生科学统一服务大学(USUHS)和奥古斯塔纳大学机构审查委员会批准并确定为豁免。结果:在21财年,83种px相关药物的CPIC等级为A、A/B或B,处方数量超过800万张。其中,超过120万张处方(15%)是给现役军人和预备役军人的,现役军人开出的前5种与pgx相关的药物是布洛芬、昂丹司琼、氢可酮、奥美拉唑和美洛昔康。本研究进一步分析了64种已知代谢频率数据的药物。在FY21,有多达632974名MHS受益人服用奥美拉唑预测CYP2C19代谢异常,这是估计代谢异常个体中处方数量最多的药物。在有严重ADE风险的药物中,别嘌呤醇高居榜首,多达301份处方提供给现役军人,估计有*58:01变异,这与中毒性表皮坏死松解的风险增加有关。结论:目前,PGx检测是MHS系统中未充分利用的资源,尽管许多与PGx相关的药物在所有具有可操作的CPIC指南的MHS受益人中广泛使用。根据已公布的普通人群中等位基因和代谢物的频率,可以预测,服用这些药物的MHS受益人中有相当多的人代谢不正常,发生药物不良事件和/或治疗失败的风险增加。考虑到包括现役军人在内的所有MHS受益人的高处方数量,这些数据应用于通知MHS中先发制人的PGx测试实施方法,目的是减少ade和治疗失败,同时提高服务成员的准备程度。
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引用次数: 0
Accompanying Editorial for: "Leadership Matters: Protective Factors for Burnout in Military Healthcare Workers". 随附社论:“领导问题:军事卫生保健工作者倦怠的保护因素”。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usaf654
Kimberly A Rhoades
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引用次数: 0
Leadership Matters: Protective Factors for Burnout in Military Healthcare Workers. 领导问题:军队医护人员职业倦怠的保护因素。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usaf650
Renée I Matos, Ronald M Cervero, John L Melton, TingLan Ma

Background: Occupational burnout in healthcare workers, especially in military medical settings, poses risks in retention, patient safety, productivity, well-being, and military readiness. Prior research suggests that sex differences exist with burnout, yet limited data exist on how drivers of burnout interact within military contexts, especially during periods of high stress such as a global pandemic. The objective of this study is to examine sex-specific differences in burnout among military healthcare workers, including the influence of demographic factors, pandemic-related stressors, and leadership characteristics.

Materials and methods: A cross-sectional survey was administered to 424 healthcare workers employed at military medical treatment facilities between January and May 2023. Participants completed the Maslach Burnout Inventory (MBI) Health Services Survey, Adaptive Leadership with Authority Scale (ALAS), and Pandemic Experiences and Perceptions Survey (PEPS). Descriptive statistics, t-tests, chi-square analysis, Pearson correlations, and ANOVAs were conducted to assess burnout dimensions-emotional exhaustion (EE), depersonalization (DP), and personal accomplishment (PA)-in relation to leadership, demographics variables, and pandemic stressors.

Results: Among 424 respondents (308 females, 116 males), overall burnout rates did not differ significantly by sex (25% males, 20% females, P = .28). However, females reported significantly higher EE than males (91.8% vs. 81.6%, P = .015, Cramer's V = 0.15). There were no differences in the levels of high DP (71.8% males, 64.6% females, P = .86) or low PA (10.5% males, 7.9% females, P = .67). Adaptive and supervisory leadership were protective against EE and DP for both sexes, but these effects were stronger and more consistent for females. Leadership was a protective factor against EE and low PA for females (r = -.34, P < .001; r = -.23, P < .001) and against EE for males (r = -.22, P = .027), though to a lesser extent. For males, tenure at the current position was inversely correlated with depersonalization (r = -.25, P = .01). Pandemic-related stress was more strongly associated with depersonalization in females. Role- and ethnicity-based interactions also revealed sex-specific patterns, with female physicians reporting higher EE and male depersonalization varying by healthcare role and ethnicity.

Conclusions: This study highlights important sex-based differences in burnout profiles and associated risk and protective factors among military healthcare workers. Findings underscore the critical role of leadership, particularly for female personnel related to EE, although tenure buffered depersonalization in males. These findings highlight the need for tailored burnout prevention strategies, particularly focused on adaptive leadership development and demographic-specific interventions.

背景:卫生保健工作者的职业倦怠,特别是在军事医疗环境中,对保留、患者安全、生产力、福祉和军事准备构成风险。先前的研究表明,倦怠存在性别差异,但关于倦怠驱动因素如何在军事背景下相互作用的数据有限,特别是在全球大流行等高压力时期。本研究旨在探讨军人医护人员职业倦怠的性别差异,包括人口统计学因素、流行病相关压力源和领导特征的影响。材料与方法:对2023年1 - 5月在军队医疗机构工作的424名医护人员进行横断面调查。参与者完成了Maslach职业倦怠量表(MBI)、适应性领导权威量表(ALAS)和流行病经验与认知调查(PEPS)。采用描述性统计、t检验、卡方分析、Pearson相关性和方差分析来评估倦怠维度——情绪耗竭(EE)、人格解体(DP)和个人成就(PA)——与领导力、人口统计学变量和流行病压力源的关系。结果:在424名被调查者中(女性308人,男性116人),总体倦怠率在性别上无显著差异(男性25%,女性20%,P = .28)。然而,女性报告的情感表达明显高于男性(91.8%比81.6%,P =。015,克莱默V = 0.15)。高DP水平(男性71.8%,女性64.6%,P =。86)或低PA(男性10.5%,女性7.9%,P = 0.67)。适应性领导和监督性领导对两性情感表达和情感表达都有保护作用,但这种作用在女性身上更强、更一致。结论:本研究强调了军人医护人员在职业倦怠概况及其相关风险和保护因素方面的重要性别差异。研究结果强调了领导的关键作用,特别是对于与情感表达相关的女性人员,尽管任期缓冲了男性的人格解体。这些发现强调了制定量身定制的职业倦怠预防策略的必要性,尤其注重适应性领导力发展和针对特定人群的干预措施。
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引用次数: 0
Return to Duty Rates in Active-Duty Military: Comparing Minimally Invasive and Open Cervical Spine Surgery. 现役军人的复职率:比较微创和开放颈椎手术。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usag014
Elder Granger, Kaitlyn Armstrong, Corbit Franks, Thomas Andre, Chip Wade, Reginald Davis

Background: Military medical readiness plays a significant role in global military operations. While the severity of combat-related trauma is evident, musculoskeletal injuries (MSK's), are the largest medical threat to deployment readiness, and accounted for more than 60% of limited duty days in 2019. Across MSK's, the spine (lumbosacral: 30%; cervical: 22%; thoracic: 10%) accounts for 62% of MSKs. In the military population, there is a tremendous economic impact in training, retaining, and deploying a service member. Return-to-duty (RTD) rates and length of time for the treatment protocols for spine surgery vary significantly in published research. Research suggests RTD rates between 3-17 months following elective traditional open lumbar and cervical spine surgery, with a RTD rate of 64% within 1 year. When examining minimally invasive lumbar spine surgery (MIS), 100% of military personal had a RTD within 3 months. Research has yet to examine the impact of MIS of the cervical spine on the RTD rates of active-duty military.

Methods: The current study retrospectively examined surgical outcomes, return to duty, and patient-centric outcomes among 156 active duty or reserve military patients who underwent an outpatient minimally invasive (n = 79) cervical spine surgery or an open (n = 77) (Laminotomy/Foraminotomy/Decompression) for the treatment of cervical spinal stenosis.

Results: Significant reductions in visual analog scale of 3.31 and neck disability index of 16.01 were observed from preoperative to postoperative time points. 77% of service members RTD in less than 1 month, 19% RTD in 1-2 months and 4% RTD between 2-3 months. There were insignificant differences reported in the open surgery group.

Discussions: MIS has been shown to reduce tissue trauma and patient complications. MIS procedures have resulted in reducing postoperative stress responses and improving the recovery process following surgery. In the active-duty military population this plays an important role in return to duty quickness. Our findings suggest that MIS procedures in an ambulatory surgery center on the cervical spine result in improved patient outcomes and reduced RTD time in active-duty military personnel.

背景:军事医疗准备在全球军事行动中发挥着重要作用。虽然与战斗有关的创伤的严重程度是显而易见的,但肌肉骨骼损伤(MSK)是对部署准备的最大医疗威胁,占2019年有限值班天数的60%以上。在MSK中,脊柱(腰骶:30%;颈椎:22%;胸椎:10%)占MSK的62%。在军队人口中,训练、保留和部署一名服役人员会产生巨大的经济影响。在已发表的研究中,脊柱外科手术的复工率和治疗方案的时间长短差异很大。研究表明,选择性传统开放腰椎和颈椎手术后3-17个月的RTD率,1年内的RTD率为64%。在微创腰椎手术(MIS)中,100%的军人在3个月内发生了RTD。目前还没有研究颈椎MIS对现役军人RTD率的影响。方法:本研究回顾性分析了156名现役或预备役军人接受门诊微创(n = 79)颈椎手术或开放(n = 77)(椎板切开术/椎间孔切开术/减压)治疗颈椎管狭窄的手术结果、重返工作和以患者为中心的结果。结果:术前至术后各时间点视觉模拟评分3.31分、颈部失能指数16.01分明显降低。77%的服役人员在不到1个月的时间内进行RTD, 19%在1-2个月内进行RTD, 4%在2-3个月内进行RTD。开放手术组的差异不显著。讨论:MIS已被证明可以减少组织创伤和患者并发症。MIS程序减少了术后应激反应,改善了术后恢复过程。在现役军人中,这对快速返回岗位起着重要作用。我们的研究结果表明,在门诊颈椎手术中心进行MIS手术可以改善患者的预后,减少现役军人的RTD时间。
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引用次数: 0
Application of the Buxton-Hanney Payback Framework to Department of War Sponsored Research on the Ukrainian Health and Trauma System Following the Russian Invasion, 2022-2025. 巴克斯顿-哈尼回报框架在陆军部资助的乌克兰健康和创伤系统研究中的应用,俄罗斯入侵后,2022-2025。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-14 DOI: 10.1093/milmed/usag046
Kyle Patrick Apilado, Vivitha Mani, Madison Chilton, Tracey Pérez Koehlmoos

Background: In response to the February 2022 Russian invasion of Ukraine's, international aid and foreign investment from the U.S. Government and regional allies flowed into the country. As part of this support, the Department of War (DoW) has supported multiple research initiatives aimed at strengthening Ukrainian healthcare, further advancing the objectives of the U.S.-Ukraine partnership. Given the scope of U.S. involvement, a thorough investigation into the outcomes of this critical research was essential to ensure accountability and improve resource allocation.

Materials and methods: To gauge the impact of these investments, the Center for Health Services Research at the Uniformed Services University of the Health Sciences conducted a Buxton-Hanney Payback Framework assessment, which systematically identifies the outcomes generated by these projects. From January 2025 to April 2025, the research team employed snowball sampling and grey literature review to identify principal investigators involved in DoW-funded Ukrainian health research. The team conducted virtual consultations to collect outcome data pertaining to the framework's domains, which were catalogued into a structured data collection instrument.

Results: The team identified 7 DoW-funded projects dedicated to Ukraine's health and trauma system. These projects yielded a total of 80 outcomes across the Buxton-Hanney framework domains, revealing a broad spectrum of impacts. These included academic knowledge outputs through publications and workforce training; policy-level contributions for healthcare; direct health benefits; and economic returns driven by workforce resilience and expansion of business operations.

Conclusions: Identified outcomes underscore the strategic value of sustained investment in military healthcare research. Investments not only support allies but also provide crucial lessons that can strengthen healthcare delivery for the U.S. Military, particularly in dynamic and conflict-affected environments. Even in their early stages, projects demonstrated immediate value by providing real-time insights that advance the partnership's objectives. Furthermore, this assessment advocates for the utilization of the Buxton-Hanney Framework as a standardized tool for assessing the outcomes and impacts for programs within the DoW.

背景:为了应对2022年2月俄罗斯入侵乌克兰,来自美国政府和地区盟友的国际援助和外国投资流入该国。作为这种支持的一部分,美国陆军部(DoW)支持了多项旨在加强乌克兰医疗保健的研究计划,进一步推进美国与乌克兰伙伴关系的目标。鉴于美国参与的范围,对这项关键研究的结果进行彻底调查对于确保问责制和改善资源分配至关重要。材料和方法:为了评估这些投资的影响,卫生科学统一服务大学卫生服务研究中心进行了一项巴克斯顿-哈尼回报框架评估,该评估系统地确定了这些项目产生的结果。从2025年1月到2025年4月,研究小组采用滚雪球抽样和灰色文献综述来确定参与dows资助的乌克兰卫生研究的主要研究者。该小组进行了虚拟协商,以收集与框架领域有关的结果数据,这些数据被编入结构化数据收集工具。结果:该团队确定了7个由美国农业部资助的项目,专门用于乌克兰的健康和创伤系统。这些项目在巴克斯顿-哈尼框架领域共产生了80项成果,揭示了广泛的影响。其中包括通过出版物和劳动力培训输出学术知识;对医疗保健的政策级贡献;直接健康福利;经济回报由劳动力弹性和业务扩张驱动。结论:确定的结果强调了军事卫生研究持续投资的战略价值。投资不仅支持盟友,而且还提供了重要的经验教训,可以加强美国军队的医疗保健服务,特别是在动态和受冲突影响的环境中。即使在早期阶段,项目也通过提供推进合作伙伴目标的实时洞察来展示其直接价值。此外,本评估提倡使用巴克斯顿-哈尼框架作为评估DoW内项目的结果和影响的标准化工具。
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引用次数: 0
The Effect of Education on Nutrition, Exercise, and Body Composition on Weight Reduction in the Czech Army. 捷克军队营养、运动和身体成分教育对减肥的影响。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-12 DOI: 10.1093/milmed/usag039
Blanka Kupsová, Vladimír Pavlík, Jana Fajfrová, Václav Šafka, Petr Lašák, Jan M Horáček

Introduction: In 2023, the prevalence of overweight and obesity in the Czech Army was 56% out of 19% in men and 38% out of 5% in women according to the body mass index (BMI). This study monitors changes in body composition following a targeted intervention in the Czech military population with the aim of reducing body weight in overweight or obese individuals.

Materials and methods: A prospective clinical study was conducted between 2023 and 2025 in six military units. Anthropometric measurements (weight, height, BMI) and body composition analysis (body fat, muscle mass, visceral fat) were performed using the bioimpedance method. Subsequently, participants received a targeted education on the results of the analysis and dietary and exercise measures were recommended. Follow-up body composition examinations were performed at 6 and 12 months.

Results: In a sample of 200 individuals (139 men, 61 women), 56% of subjects had a normal body fat percentage (PBF), (men up to 20%, women up to 28% inclusive). There was no significant change in monitored parameters in individuals with a normal PBF, but individuals with an above-normal PBF experienced weight loss (-0.8 kg in men, -3.6 kg in women) without any reduction in muscle mass. A statistically significant decrease in PBF (0.8% in men, 2% in women) and visceral fat was found in the entire sample during the follow-up measurement after 6 months.

Conclusion: This study demonstrates that a structured, physician-led, individualized intervention effectively reduces body fat and visceral adiposity while preserving muscle mass and improving key health parameters in overweight and obese soldiers. The feasible model highlights the importance of personalized, education-based prevention and has potential for broader application beyond the military.

Clinical trial registration:

根据身体质量指数(BMI), 2023年捷克军队中超重和肥胖的患病率为19%的男性中有56%,5%的女性中有38%。本研究监测了捷克军人群体在进行有针对性的干预后身体成分的变化,目的是减轻超重或肥胖个体的体重。材料与方法:于2023年至2025年在6个军事单位进行前瞻性临床研究。采用生物阻抗法进行人体测量(体重、身高、BMI)和身体成分分析(体脂、肌肉质量、内脏脂肪)。随后,参与者接受了有关分析结果的有针对性的教育,并建议采取饮食和运动措施。随访6个月和12个月进行体成分检查。结果:在200人的样本中(139名男性,61名女性),56%的受试者具有正常的体脂百分比(PBF),(男性高达20%,女性高达28%)。在PBF正常的个体中,监测参数没有显著变化,但PBF高于正常的个体体重减轻(男性-0.8 kg,女性-3.6 kg),而肌肉质量没有任何减少。在6个月后的随访测量中,整个样本的PBF(男性为0.8%,女性为2%)和内脏脂肪均有统计学意义的下降。结论:本研究表明,一种结构化的、医生主导的、个性化的干预可以有效地减少超重和肥胖士兵的体脂和内脏脂肪,同时保持肌肉质量,改善关键健康参数。这种可行的模式强调了个性化、基于教育的预防的重要性,并有可能在军事以外得到更广泛的应用。临床试验注册:
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引用次数: 0
An Assessment of Repositories for Researching Military Exposures and Veterans Health. 军事暴露与退伍军人健康研究知识库评估
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-12 DOI: 10.1093/milmed/usag026
Jacob B Lindheimer, Shantel Peters, Jaraad Ramkissoon, Laila Abdullah, Heather Bogle, Rachel Wright, David Thompson, Amy Lallier, Shaili Bhavsar, Rosalinda Desrochers, Israel Christie, Kellie J Sims, Joanna Gaitens, Melissa McDiarmid, Rudolph C Johnson, Drew Helmer

Introduction: Millions of United States (U.S.) veterans report exposures to a wide range of chemical, physical, radiological, and biological agents during their military service (i.e., military exposures). Given the negative implications of military exposures for veterans health, high quality research is needed to inform disability policy and healthcare strategies. Existing repositories may help streamline research efforts but have not been comparatively evaluated. We conducted a rapid review to identify repositories for streamlining primary and secondary research on long-term health effects of military exposures.

Materials and methods: Repositories were included for analysis if they contained data or biospecimens that were collected from current or former U.S. service members. Six criteria concerning inventory (i.e., measures of exposures, biospecimens, personally identifiable information) and research permissions (i.e., future use, future contact, and sharing) were used to make a collective assessment of utility for military exposures research. Repositories were also descriptively coded for specific types of exposure-related data (i.e., air pollutants, chemicals, metals, radiation, warfare agents) and the exposure assessment method (i.e., direct or indirect).

Results: Of 52 identified resources, 29 repositories were eligible for further analysis. The most frequently represented exposure-related data type was air pollutants (n = 13), followed by chemicals (n = 11), warfare agents (n = 8), radiation (n = 6), and metals (n = 5). Most repositories used indirect (n = 24) versus direct (n = 5) exposure assessment methods. Eight repositories met al. 6 assessment criteria.

Conclusions: We identified 8 repositories that are useful for streamlining research on the long-term health outcomes of military exposures. Future efforts that focus on evaluating their data and biospecimen quality will further distinguish these resources regarding readiness to produce high-quality research that informs disability policy and healthcare strategies.

数以百万计的美国退伍军人报告说,他们在服兵役期间暴露于各种化学、物理、放射和生物制剂(即军事暴露)。鉴于军事接触对退伍军人健康的负面影响,需要进行高质量的研究,为残疾政策和保健战略提供信息。现有的存储库可能有助于简化研究工作,但尚未进行比较评估。我们进行了一项快速审查,以确定简化军事接触对健康长期影响的初级和二级研究的存储库。材料和方法:如果存储库包含从现任或前任美国服务人员收集的数据或生物标本,则纳入分析。关于库存(即暴露措施、生物标本、个人可识别信息)和研究许可(即未来使用、未来接触和共享)的六个标准被用于对军事暴露研究的效用进行集体评估。存储库还对特定类型的与暴露有关的数据(即空气污染物、化学品、金属、辐射、战剂)和暴露评估方法(即直接或间接)进行了描述性编码。结果:在鉴定的52个资源库中,有29个资源库符合进一步分析的条件。最常见的与暴露有关的数据类型是空气污染物(n = 13),其次是化学品(n = 11)、战剂(n = 8)、辐射(n = 6)和金属(n = 5)。大多数储存库采用间接(n = 24)和直接(n = 5)暴露评估方法。8个知识库满足所有6个评估标准。结论:我们确定了8个有助于简化军事暴露长期健康结果研究的存储库。今后着重于评估其数据和生物标本质量的工作将进一步区分这些资源是否准备开展高质量的研究,为残疾政策和保健战略提供信息。
{"title":"An Assessment of Repositories for Researching Military Exposures and Veterans Health.","authors":"Jacob B Lindheimer, Shantel Peters, Jaraad Ramkissoon, Laila Abdullah, Heather Bogle, Rachel Wright, David Thompson, Amy Lallier, Shaili Bhavsar, Rosalinda Desrochers, Israel Christie, Kellie J Sims, Joanna Gaitens, Melissa McDiarmid, Rudolph C Johnson, Drew Helmer","doi":"10.1093/milmed/usag026","DOIUrl":"https://doi.org/10.1093/milmed/usag026","url":null,"abstract":"<p><strong>Introduction: </strong>Millions of United States (U.S.) veterans report exposures to a wide range of chemical, physical, radiological, and biological agents during their military service (i.e., military exposures). Given the negative implications of military exposures for veterans health, high quality research is needed to inform disability policy and healthcare strategies. Existing repositories may help streamline research efforts but have not been comparatively evaluated. We conducted a rapid review to identify repositories for streamlining primary and secondary research on long-term health effects of military exposures.</p><p><strong>Materials and methods: </strong>Repositories were included for analysis if they contained data or biospecimens that were collected from current or former U.S. service members. Six criteria concerning inventory (i.e., measures of exposures, biospecimens, personally identifiable information) and research permissions (i.e., future use, future contact, and sharing) were used to make a collective assessment of utility for military exposures research. Repositories were also descriptively coded for specific types of exposure-related data (i.e., air pollutants, chemicals, metals, radiation, warfare agents) and the exposure assessment method (i.e., direct or indirect).</p><p><strong>Results: </strong>Of 52 identified resources, 29 repositories were eligible for further analysis. The most frequently represented exposure-related data type was air pollutants (n = 13), followed by chemicals (n = 11), warfare agents (n = 8), radiation (n = 6), and metals (n = 5). Most repositories used indirect (n = 24) versus direct (n = 5) exposure assessment methods. Eight repositories met al. 6 assessment criteria.</p><p><strong>Conclusions: </strong>We identified 8 repositories that are useful for streamlining research on the long-term health outcomes of military exposures. Future efforts that focus on evaluating their data and biospecimen quality will further distinguish these resources regarding readiness to produce high-quality research that informs disability policy and healthcare strategies.</p>","PeriodicalId":18638,"journal":{"name":"Military Medicine","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Higher Baseline Diet Quality Is Positively Associated With Academic and Physical Performance Among United States Military Academy Cadets. 在美国军事学院学员中,较高的基线饮食质量与学业和身体表现呈正相关。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-12 DOI: 10.1093/milmed/usag032
Bridget A Owens, Claire C Whitney, Adrienne Hatch-McChesney, Kristina R Fauser, Kathryn A Davel, Christine N Jordhamo, Michelle N Ott, Diana M Thomas, J Philip Karl, Harris R Lieberman, James P McClung, Steven J Condly, Tracey J Smith
<p><strong>Introduction: </strong>Service Academy Cadets are exposed to physical and cognitive stressors including a rigorous schedule composed of academic, athletic, physical, and military training requirements, along with chronic sleep restriction, during and across semesters. Although research has examined stress-sleep relationships in military personnel and college students, the interrelationships between stress, sleep, and dietary quality among service academy cadets requires further study to inform interventions that optimize health and performance. This secondary analysis of a prospective cohort study examined interrelationships between stress, sleep, and dietary quality among cadets' in the setting of academic and athletic rigor.</p><p><strong>Materials and methods: </strong>United States Military Academy (USMA) cadets (n = 268; age = 20 ± 2 years; body mass index [BMI] = 25.2 ± 2.7 kg/m2) completed baseline (BL, approximately 1 month into the Fall semester) and follow-up (POST, ∼12 days before final December exams) measures including the Perceived Stress Scale (PSS), Pittsburgh Sleep Quality Index (PSQI), and VioScreen food frequency questionnaire. Diet quality was evaluated using the Healthy Eating Index-2020 (HEI-2020). Academic, military, and physical performance were assessed using final semester scores and Army Combat Fitness Test (ACFT) scores.</p><p><strong>Results: </strong>Perceived stress scale scores indicated moderate stress levels that significantly decreased from BL to POST [(mean ± SD): 22.7 ± 7.0 to 20.8 ± 7.4, respectively, P < .001]. Pittsburgh Sleep Quality Index scores indicated poor sleep quality at both timepoints but showed modest improvement over time (6.2 ± 2.4 to 6.0 ± 2.3, respectively, P < .001). Significant positive correlations were observed between PSS and PSQI scores at PRE (r = 0.36, P < .001) and POST (r = 0.46, P < .001), indicating that reduced stress was associated with improved sleep quality. Total HEI scores fell in the "needs improvement" range, declined from PRE (60.8 ± 9.5) to POST (58.4 ± 10.3, P < .001), and were not correlated with stress or sleep measures. Higher diet quality at baseline was associated with higher academic scores at the end of the term (B = 0.01 ± 0.01, P = .004), physical scores at the end of the term (B = 0.01 ± 0.01, P = .018), and ACFT scores at the beginning of the term (B = 0.98 ± 0.24, P < .0001).</p><p><strong>Conclusions: </strong>This study revealed suboptimal diet quality among USMA cadets throughout the academic semester. Higher diet quality at baseline was associated with higher academic and physical scores at the end of the term. Significant associations between reduced stress and improved sleep quality were noted, however both measures remained within suboptimal ranges indicating persistent moderate stress and poor sleep quality in this population. The findings demonstrated connections between diet quality with academic and physical performance, and support the
简介:军校学员暴露在身体和认知压力源中,包括严格的时间表,包括学术、运动、身体和军事训练要求,以及长期睡眠限制,在学期期间和整个学期。虽然研究已经检查了军事人员和大学生的压力-睡眠关系,但在服务学院学员中,压力、睡眠和饮食质量之间的相互关系需要进一步研究,以告知优化健康和表现的干预措施。这是一项前瞻性队列研究的二次分析,研究了在学术和运动严格性的背景下,学员的压力、睡眠和饮食质量之间的相互关系。材料和方法:美国军事学院(USMA)学员(n = 268;年龄= 20±2岁;体重指数[BMI] = 25.2±2.7 kg/m2)完成基线(BL,大约在秋季学期开始1个月)和随访(POST, 12月期末考试前12天)测量,包括感知压力量表(PSS)、匹兹堡睡眠质量指数(PSQI)和VioScreen食物频率问卷。采用健康饮食指数-2020 (HEI-2020)评估饮食质量。学业、军事和身体表现采用期末成绩和陆军战斗体能测试(ACFT)分数进行评估。结果:感知压力量表得分显示,从BL到POST,中等压力水平显著下降[(mean±SD):分别为22.7±7.0至20.8±7.4]P。结论:本研究揭示了USMA学员在整个学期的饮食质量欠佳。基线时较高的饮食质量与学期结束时较高的学业和身体分数相关。研究人员注意到,压力减轻和睡眠质量改善之间存在显著关联,但这两项指标仍处于次优范围,表明该人群持续存在中等压力和较差的睡眠质量。研究结果证明了饮食质量与学业和身体表现之间的联系,并支持持续实施和评估有针对性的营养策略,以增加营养食品的消费,特别是考虑到学员在食物选择可能受到限制的餐饮设施中消费大部分膳食。
{"title":"Higher Baseline Diet Quality Is Positively Associated With Academic and Physical Performance Among United States Military Academy Cadets.","authors":"Bridget A Owens, Claire C Whitney, Adrienne Hatch-McChesney, Kristina R Fauser, Kathryn A Davel, Christine N Jordhamo, Michelle N Ott, Diana M Thomas, J Philip Karl, Harris R Lieberman, James P McClung, Steven J Condly, Tracey J Smith","doi":"10.1093/milmed/usag032","DOIUrl":"https://doi.org/10.1093/milmed/usag032","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Service Academy Cadets are exposed to physical and cognitive stressors including a rigorous schedule composed of academic, athletic, physical, and military training requirements, along with chronic sleep restriction, during and across semesters. Although research has examined stress-sleep relationships in military personnel and college students, the interrelationships between stress, sleep, and dietary quality among service academy cadets requires further study to inform interventions that optimize health and performance. This secondary analysis of a prospective cohort study examined interrelationships between stress, sleep, and dietary quality among cadets' in the setting of academic and athletic rigor.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;United States Military Academy (USMA) cadets (n = 268; age = 20 ± 2 years; body mass index [BMI] = 25.2 ± 2.7 kg/m2) completed baseline (BL, approximately 1 month into the Fall semester) and follow-up (POST, ∼12 days before final December exams) measures including the Perceived Stress Scale (PSS), Pittsburgh Sleep Quality Index (PSQI), and VioScreen food frequency questionnaire. Diet quality was evaluated using the Healthy Eating Index-2020 (HEI-2020). Academic, military, and physical performance were assessed using final semester scores and Army Combat Fitness Test (ACFT) scores.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Perceived stress scale scores indicated moderate stress levels that significantly decreased from BL to POST [(mean ± SD): 22.7 ± 7.0 to 20.8 ± 7.4, respectively, P &lt; .001]. Pittsburgh Sleep Quality Index scores indicated poor sleep quality at both timepoints but showed modest improvement over time (6.2 ± 2.4 to 6.0 ± 2.3, respectively, P &lt; .001). Significant positive correlations were observed between PSS and PSQI scores at PRE (r = 0.36, P &lt; .001) and POST (r = 0.46, P &lt; .001), indicating that reduced stress was associated with improved sleep quality. Total HEI scores fell in the \"needs improvement\" range, declined from PRE (60.8 ± 9.5) to POST (58.4 ± 10.3, P &lt; .001), and were not correlated with stress or sleep measures. Higher diet quality at baseline was associated with higher academic scores at the end of the term (B = 0.01 ± 0.01, P = .004), physical scores at the end of the term (B = 0.01 ± 0.01, P = .018), and ACFT scores at the beginning of the term (B = 0.98 ± 0.24, P &lt; .0001).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study revealed suboptimal diet quality among USMA cadets throughout the academic semester. Higher diet quality at baseline was associated with higher academic and physical scores at the end of the term. Significant associations between reduced stress and improved sleep quality were noted, however both measures remained within suboptimal ranges indicating persistent moderate stress and poor sleep quality in this population. The findings demonstrated connections between diet quality with academic and physical performance, and support the","PeriodicalId":18638,"journal":{"name":"Military Medicine","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146181126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redonation Attempts Among Potential Donors With Pre-donation Deferrals in a Military Blood Donation Center. 某军事献血中心潜在献血者的再次献血尝试。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-02-12 DOI: 10.1093/milmed/usag057
Somin Kwon, Sorana Raiciulescu, Brian G Casleton, Glorimar Z Rivera, Melita M Gella, Erin L Winkler, Angela B Osuna, Theresa M Casey, Heather C Yun, Joseph E Marcus

Introduction: All prospective blood donors who report behaviors or conditions that may increase risk of transfusion-transmitted infection (TTI) are temporarily deferred from donating. In this study, we evaluate how deferrals for TTI risk impact future donation attempts, ultimately informing how deferral policy changes may affect the military population.

Materials and methods: This retrospective chart review evaluated all blood donors with pre-donation deferrals at a single site between October 2019 and December 2022. Among the 14 deferral categories, 7 were classified as behaviors or conditions that increase risk of TTI. The rate of donation reattempts within the study period was assessed in donors deferred for TTI risk and compared to that of donors deferred for low hemoglobin matched by sex, age, and military training status.

Results: Six thousand three hundred and fifty two (12.8%) of the 49,613 blood donors identified during the study had a pre-donation deferral. The most common reason for pre-donation deferral was anemia (54.2%), but TTI-risk accounted for a significant fraction of deferrals (10.7%). We found that donors who were deferred for TTI risk were significantly less likely to attempt redonation during the study period compared to those deferred for anemia (P < .001). On multivariate analysis, donors deferred for men who have sex with men and travel or residence in a malaria-endemic area were independently associated with a decreased redonation attempt rate and increased time to reattempt.

Conclusion: Pre-donation deferrals for TTI risk were associated with a decreased rate of redonation and increased time to reattempt compared to donors deferred for anemia.

所有报告可能增加输血传播感染(TTI)风险的行为或情况的潜在献血者暂时推迟献血。在本研究中,我们评估了TTI风险的延迟如何影响未来的捐赠尝试,最终告知延迟政策变化如何影响军人人群。材料和方法:本回顾性图表回顾评估了2019年10月至2022年12月期间在单一地点进行献血前延迟的所有献血者。在14个延迟类别中,7个被归类为增加TTI风险的行为或条件。在研究期间,评估了因TTI风险而推迟捐献的献血者的再捐献率,并将其与因低血红蛋白而推迟捐献的献血者的再捐献率与性别、年龄和军事训练状况相匹配进行了比较。结果:在研究期间确定的49,613名献血者中,有6,352人(12.8%)有捐献前延迟。捐献前延迟的最常见原因是贫血(54.2%),但tti风险占延迟的很大一部分(10.7%)。我们发现,在研究期间,与因贫血而推迟的献血者相比,因TTI风险而推迟的献血者尝试再捐献的可能性显著降低(P结论:与因贫血而推迟的献血者相比,因TTI风险而推迟的献血者再捐献率降低,再捐献时间增加。
{"title":"Redonation Attempts Among Potential Donors With Pre-donation Deferrals in a Military Blood Donation Center.","authors":"Somin Kwon, Sorana Raiciulescu, Brian G Casleton, Glorimar Z Rivera, Melita M Gella, Erin L Winkler, Angela B Osuna, Theresa M Casey, Heather C Yun, Joseph E Marcus","doi":"10.1093/milmed/usag057","DOIUrl":"https://doi.org/10.1093/milmed/usag057","url":null,"abstract":"<p><strong>Introduction: </strong>All prospective blood donors who report behaviors or conditions that may increase risk of transfusion-transmitted infection (TTI) are temporarily deferred from donating. In this study, we evaluate how deferrals for TTI risk impact future donation attempts, ultimately informing how deferral policy changes may affect the military population.</p><p><strong>Materials and methods: </strong>This retrospective chart review evaluated all blood donors with pre-donation deferrals at a single site between October 2019 and December 2022. Among the 14 deferral categories, 7 were classified as behaviors or conditions that increase risk of TTI. The rate of donation reattempts within the study period was assessed in donors deferred for TTI risk and compared to that of donors deferred for low hemoglobin matched by sex, age, and military training status.</p><p><strong>Results: </strong>Six thousand three hundred and fifty two (12.8%) of the 49,613 blood donors identified during the study had a pre-donation deferral. The most common reason for pre-donation deferral was anemia (54.2%), but TTI-risk accounted for a significant fraction of deferrals (10.7%). We found that donors who were deferred for TTI risk were significantly less likely to attempt redonation during the study period compared to those deferred for anemia (P < .001). On multivariate analysis, donors deferred for men who have sex with men and travel or residence in a malaria-endemic area were independently associated with a decreased redonation attempt rate and increased time to reattempt.</p><p><strong>Conclusion: </strong>Pre-donation deferrals for TTI risk were associated with a decreased rate of redonation and increased time to reattempt compared to donors deferred for anemia.</p>","PeriodicalId":18638,"journal":{"name":"Military Medicine","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146180444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Military Medicine
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