Pub Date : 2019-11-01DOI: 10.1016/j.ymthe.2019.09.016
María Cristina Ballesteros-Briones, E. Martišová, E. Casales, Noelia Silva-Pilipich, M. Buñuales, Javier Galindo, U. Mancheño, M. Gorraiz, J. Lasarte, G. Kochan, D. Escors, A. R. Sánchez-Paulete, I. Melero, J. Prieto, R. Hernández-Alcoceba, S. Hervás-Stubbs, C. Smerdou
{"title":"Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses.","authors":"María Cristina Ballesteros-Briones, E. Martišová, E. Casales, Noelia Silva-Pilipich, M. Buñuales, Javier Galindo, U. Mancheño, M. Gorraiz, J. Lasarte, G. Kochan, D. Escors, A. R. Sánchez-Paulete, I. Melero, J. Prieto, R. Hernández-Alcoceba, S. Hervás-Stubbs, C. Smerdou","doi":"10.1016/j.ymthe.2019.09.016","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.016","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85609336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.1016/j.ymthe.2019.07.018
E. Sayers, S. Peel, Anna Schantz, Richard M. England, Maya Beano, Stephanie M. Bates, Arpan S. Desai, S. Puri, M. Ashford, A. Jones
{"title":"Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression.","authors":"E. Sayers, S. Peel, Anna Schantz, Richard M. England, Maya Beano, Stephanie M. Bates, Arpan S. Desai, S. Puri, M. Ashford, A. Jones","doi":"10.1016/j.ymthe.2019.07.018","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.07.018","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73343946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-22DOI: 10.1016/j.ymthe.2019.10.011
D. Duan
{"title":"Micro-utrophin Therapy for Duchenne Muscular Dystrophy.","authors":"D. Duan","doi":"10.1016/j.ymthe.2019.10.011","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.011","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72980244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-17DOI: 10.1016/j.ymthe.2019.10.005
R. Herzog, G. Pierce
{"title":"Liver Gene Therapy: Reliable and Durable?","authors":"R. Herzog, G. Pierce","doi":"10.1016/j.ymthe.2019.10.005","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.005","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89027739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-02DOI: 10.1016/j.ymthe.2019.09.022
D. Zamarin
{"title":"Immunomodulatory Drugs Encoded by Oncolytic Viruses: Is the Whole Greater Than the Sum?","authors":"D. Zamarin","doi":"10.1016/j.ymthe.2019.09.022","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.022","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77185565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.1016/j.ymthe.2019.06.018
M. Bai, Jialu Li, Haiou Yang, Haiyang Zhang, Zhengyang Zhou, T. Deng, Kegan Zhu, Tao Ning, Q. Fan, G. Ying, Y. Ba
{"title":"miR-135b Delivered by Gastric Tumor Exosomes Inhibits FOXO1 Expression in Endothelial Cells and Promotes Angiogenesis.","authors":"M. Bai, Jialu Li, Haiou Yang, Haiyang Zhang, Zhengyang Zhou, T. Deng, Kegan Zhu, Tao Ning, Q. Fan, G. Ying, Y. Ba","doi":"10.1016/j.ymthe.2019.06.018","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.06.018","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"80 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73037620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.1016/j.ymthe.2019.09.011
B. Byrne
{"title":"Neuromuscular Gene Therapy: Catching the Wave of Positive Early Studies Is Expected to Crest in Product Approvals.","authors":"B. Byrne","doi":"10.1016/j.ymthe.2019.09.011","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.011","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75530150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.1016/J.YMTHE.2019.06.007
A. Hombach, G. Rappl, H. Abken
{"title":"Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors.","authors":"A. Hombach, G. Rappl, H. Abken","doi":"10.1016/J.YMTHE.2019.06.007","DOIUrl":"https://doi.org/10.1016/J.YMTHE.2019.06.007","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81709151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.1016/j.ymthe.2019.07.006
Mei-yue Liu, Jia-rui Yu, Dan Wang, Y. Niu, Si-yuan Chen, Peng Gao, Zhao Yang, Huan Wang, Jie Zhang, Chao Zhang, Yue Zhao, Wanning Hu, G. Sun
{"title":"Epigenetically Upregulated MicroRNA-602 Is Involved in a Negative Feedback Loop with FOXK2 in Esophageal Squamous Cell Carcinoma.","authors":"Mei-yue Liu, Jia-rui Yu, Dan Wang, Y. Niu, Si-yuan Chen, Peng Gao, Zhao Yang, Huan Wang, Jie Zhang, Chao Zhang, Yue Zhao, Wanning Hu, G. Sun","doi":"10.1016/j.ymthe.2019.07.006","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.07.006","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79870641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.1016/j.ymthe.2019.06.017
Srinivas Pittala, Y. Krelin, Y. Kuperman, V. Shoshan-Barmatz
{"title":"A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model.","authors":"Srinivas Pittala, Y. Krelin, Y. Kuperman, V. Shoshan-Barmatz","doi":"10.1016/j.ymthe.2019.06.017","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.06.017","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77741457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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