Pub Date : 2020-01-01DOI: 10.1016/j.ymthe.2019.10.010
Changwen Deng, Jingjing Zhao, Shixin Zhou, Jiebin Dong, Jixiang Cao, Junshuang Gao, Yun Bai, H. Deng
{"title":"The Vascular Disrupting Agent CA4P Improves the Antitumor Efficacy of CAR-T Cells in Preclinical Models of Solid Human Tumors.","authors":"Changwen Deng, Jingjing Zhao, Shixin Zhou, Jiebin Dong, Jixiang Cao, Junshuang Gao, Yun Bai, H. Deng","doi":"10.1016/j.ymthe.2019.10.010","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.010","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73663500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.1016/j.ymthe.2019.10.002
R. V. van der Kwast, Tamar Woudenberg, Paul H.A. Quax, A. Nossent
{"title":"MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia.","authors":"R. V. van der Kwast, Tamar Woudenberg, Paul H.A. Quax, A. Nossent","doi":"10.1016/j.ymthe.2019.10.002","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.002","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80410180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.07.020
Jiayan Fan, Yangfan Xu, Xu-yang Wen, S. Ge, Renbing Jia, He Zhang, Xianqun Fan
{"title":"A Cohesin-Mediated Intrachromosomal Loop Drives Oncogenic ROR lncRNA to Accelerate Tumorigenesis.","authors":"Jiayan Fan, Yangfan Xu, Xu-yang Wen, S. Ge, Renbing Jia, He Zhang, Xianqun Fan","doi":"10.1016/j.ymthe.2019.07.020","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.07.020","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83742595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.10.006
I. Sariyer, J. Gordon, T. Burdo, Hassen S Wollebo, Eleonora Gianti, Martina Donadoni, A. Bellizzi, S. Cicalese, Regina Loomis, J. Robinson, V. Carnevale, J. Steiner, M. H. Ozdener, Andrew D. Miller, S. Amini, M. Klein, K. Khalili
{"title":"Suppression of Zika Virus Infection in the Brain by the Antiretroviral Drug Rilpivirine.","authors":"I. Sariyer, J. Gordon, T. Burdo, Hassen S Wollebo, Eleonora Gianti, Martina Donadoni, A. Bellizzi, S. Cicalese, Regina Loomis, J. Robinson, V. Carnevale, J. Steiner, M. H. Ozdener, Andrew D. Miller, S. Amini, M. Klein, K. Khalili","doi":"10.1016/j.ymthe.2019.10.006","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.006","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82332034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.08.012
Luqman Jubair, Sora Fallaha, N. McMillan
{"title":"Systemic Delivery of CRISPR/Cas9 Targeting HPV Oncogenes Is Effective at Eliminating Established Tumors.","authors":"Luqman Jubair, Sora Fallaha, N. McMillan","doi":"10.1016/j.ymthe.2019.08.012","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.08.012","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88924157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.08.006
Chang Li, Arpit Mishra, Sucheol Gil, Meng Wang, A. Georgakopoulou, T. Papayannopoulou, R. D. Hawkins, A. Lieber
{"title":"Targeted Integration and High-Level Transgene Expression in AAVS1 Transgenic Mice after In Vivo HSC Transduction with HDAd5/35++ Vectors.","authors":"Chang Li, Arpit Mishra, Sucheol Gil, Meng Wang, A. Georgakopoulou, T. Papayannopoulou, R. D. Hawkins, A. Lieber","doi":"10.1016/j.ymthe.2019.08.006","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.08.006","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78832809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.08.017
A. Rashnonejad, Gholamhossein Amini Chermahini, Cumhur Gündüz, H. Onay, A. Aykut, B. Durmaz, M. Baka, Q. Su, G. Gao, F. Özkınay
{"title":"Fetal Gene Therapy Using a Single Injection of Recombinant AAV9 Rescued SMA Phenotype in Mice.","authors":"A. Rashnonejad, Gholamhossein Amini Chermahini, Cumhur Gündüz, H. Onay, A. Aykut, B. Durmaz, M. Baka, Q. Su, G. Gao, F. Özkınay","doi":"10.1016/j.ymthe.2019.08.017","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.08.017","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74454143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/j.ymthe.2019.08.010
M. Izco, J. Blesa, M. Schleef, M. Schmeer, Riccardo Porcari, R. Al-Shawi, S. Ellmerich, María de Toro, C. Gardiner, Y. Seow, Alejandro Reinares-Sebastián, R. Forcén, J. Paul Simons, V. Bellotti, J. Mark Cooper, L. Álvarez-Erviti
{"title":"Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology.","authors":"M. Izco, J. Blesa, M. Schleef, M. Schmeer, Riccardo Porcari, R. Al-Shawi, S. Ellmerich, María de Toro, C. Gardiner, Y. Seow, Alejandro Reinares-Sebastián, R. Forcén, J. Paul Simons, V. Bellotti, J. Mark Cooper, L. Álvarez-Erviti","doi":"10.1016/j.ymthe.2019.08.010","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.08.010","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79187351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1016/J.YMTHE.2019.08.007
M. Melo, E. Porter, Y. Zhang, Murillo Silva, Na Li, Brian S. Dobosh, Alessia Liguori, Patrick D. Skog, E. Landais, S. Menis, D. Sok, D. Nemazee, W. Schief, Ron Weiss, D. Irvine
{"title":"Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.","authors":"M. Melo, E. Porter, Y. Zhang, Murillo Silva, Na Li, Brian S. Dobosh, Alessia Liguori, Patrick D. Skog, E. Landais, S. Menis, D. Sok, D. Nemazee, W. Schief, Ron Weiss, D. Irvine","doi":"10.1016/J.YMTHE.2019.08.007","DOIUrl":"https://doi.org/10.1016/J.YMTHE.2019.08.007","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82012755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.1016/j.ymthe.2019.11.015
Fangfang Zhang, Xuelei Ruan, Jun Ma, Xiaobai Liu, Jian Zheng, Yunhui Liu, Libo Liu, S. Shen, Lianqi Shao, Di Wang, Chunqing Yang, H. Cai, Zhen Li, Ziyi Feng, Yixue Xue
{"title":"DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells.","authors":"Fangfang Zhang, Xuelei Ruan, Jun Ma, Xiaobai Liu, Jian Zheng, Yunhui Liu, Libo Liu, S. Shen, Lianqi Shao, Di Wang, Chunqing Yang, H. Cai, Zhen Li, Ziyi Feng, Yixue Xue","doi":"10.1016/j.ymthe.2019.11.015","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.11.015","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84672921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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