Regional therapies are a key component of treatment of hepatocellular cancers (HCCs) and include transcatheter arterial embolization (TAE) with
局部治疗是肝细胞癌(hcc)治疗的关键组成部分，包括经导管动脉栓塞(TAE)
{"title":"Long-Term Outcomes with TACE plus RFA for Hepatocellular Cancers","authors":"D. Ilson","doi":"10.1056/NEJM-JW.NA54187","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54187","url":null,"abstract":"Regional therapies are a key component of treatment of hepatocellular cancers (HCCs) and include transcatheter arterial embolization (TAE) with","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76097570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
What role does computed tomographic angiography (CTA) play in patients with acute chest pain who are at intermediate risk for acute coronary syndrome
ct血管造影(CTA)在急性胸痛患者急性冠状动脉综合征中有何作用
{"title":"Early CT Angiography for Suspected Acute Coronary Syndromes","authors":"K. Fleischmann, Facc","doi":"10.1056/NEJM-JW.NA54154","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54154","url":null,"abstract":"What role does computed tomographic angiography (CTA) play in patients with acute chest pain who are at intermediate risk for acute coronary syndrome","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75176965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery calcium (CAC) can help to predict risk for adverse cardiovascular (CV) events. In this analysis of a large South Korean cohort of
冠状动脉钙(CAC)可以帮助预测心血管不良事件的风险。在对韩国一大群人的分析中
{"title":"Physical Activity and Elevated Coronary Artery Calcium Scores","authors":"K. Fleischmann, Facc","doi":"10.1056/NEJM-JW.NA54168","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54168","url":null,"abstract":"Coronary artery calcium (CAC) can help to predict risk for adverse cardiovascular (CV) events. In this analysis of a large South Korean cohort of","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81291916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Among people who have the same disease, a particular drug can vary greatly in its effectiveness and adverse effects. Although some of this variability
在患有相同疾病的人群中，一种特定药物的疗效和副作用可能差别很大。尽管有些变化
{"title":"Interactions of Gut Bacteria and Oral Drugs Might Have Clinical Implications","authors":"A. Komaroff","doi":"10.1056/NEJM-JW.NA54173","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54173","url":null,"abstract":"Among people who have the same disease, a particular drug can vary greatly in its effectiveness and adverse effects. Although some of this variability","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88316399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Live Zoster Vaccine Appears Safe for Patients on Immunosuppressive Therapy","authors":"H. Sahly","doi":"10.1056/NEJM-JW.NA54130","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54130","url":null,"abstract":"Risk for herpes zoster (shingles) rises with age and immunocompromised status due to disease or therapy. Live attenuated zoster vaccine (ZVL) is","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90393346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Streptococcus pneumoniae is the chief cause of community-acquired pneumonia (CAP) among older adults. Although the 13-valent pneumococcal conjugate
肺炎链球菌是老年人社区获得性肺炎(CAP)的主要原因。虽然13价肺炎球菌结合
{"title":"Rethinking Pneumococcal Vaccine Recommendations for Adults","authors":"N. Ampel","doi":"10.1056/NEJM-JW.NA54161","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54161","url":null,"abstract":"Streptococcus pneumoniae is the chief cause of community-acquired pneumonia (CAP) among older adults. Although the 13-valent pneumococcal conjugate","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89210711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As the FDA and CDC continue to assess the utility of COVID-19 booster vaccinations, three more studies expand our understanding of longer-term
随着FDA和CDC继续评估COVID-19强化疫苗的效用，另外三项研究扩大了我们对长期疫苗的理解
{"title":"To Boost or Not to Boost (A Few More Takes)","authors":"R. Ellison","doi":"10.1056/NEJM-JW.NA54181","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54181","url":null,"abstract":"As the FDA and CDC continue to assess the utility of COVID-19 booster vaccinations, three more studies expand our understanding of longer-term","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81023348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The link between gut inflammation and neoplasia involves enterotoxigenic strains of Bacteroides fragilis (ETBF) in the microbiome that harbor the B.
肠道炎症和肿瘤之间的联系涉及微生物组中含有易碎拟杆菌(ETBF)的产肠毒素菌株。
{"title":"Pro-Inflammatory Commensal Bacteria Linked to Colorectal Cancer","authors":"G. Sakoulas","doi":"10.1056/NEJM-JW.NA54138","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54138","url":null,"abstract":"The link between gut inflammation and neoplasia involves enterotoxigenic strains of Bacteroides fragilis (ETBF) in the microbiome that harbor the B.","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75797414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sponsoring Organization: The American Society of Hematology (ASH)Background and ObjectiveSickle cell disease can have devastating clinical
赞助组织:美国血液学会(ASH)背景和目的:镰状细胞病具有毁灭性的临床
{"title":"Transplantation for Sickle Cell Disease","authors":"B. Stein, Mhs","doi":"10.1056/NEJM-JW.NA54183","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54183","url":null,"abstract":"Sponsoring Organization: The American Society of Hematology (ASH)Background and ObjectiveSickle cell disease can have devastating clinical","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83021773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The RESTART trial investigators previously reported that restarting antiplatelet therapy for survivors of intracerebral hemorrhage (ICH) who were on
RESTART试验研究人员先前报道了重新开始抗血小板治疗脑出血(ICH)幸存者
{"title":"Restarting Antiplatelet Therapy After ICH in Patients Previously on Antithrombotic Therapy","authors":"A. Kim","doi":"10.1056/NEJM-JW.NA54155","DOIUrl":"https://doi.org/10.1056/NEJM-JW.NA54155","url":null,"abstract":"The RESTART trial investigators previously reported that restarting antiplatelet therapy for survivors of intracerebral hemorrhage (ICH) who were on","PeriodicalId":19048,"journal":{"name":"NEJM Journal Watch","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78557482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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