Pub Date : 2026-02-02DOI: 10.1038/d41573-026-00014-8
Andrew S Robertson, Nahid Latif, Raymond C Votzmeyer, Natalie Tolli, Mark Taisey, Kevin Bugin, Kathy Williams, Michael Garvin, Max Wegner, Antoine Manson, Jennifer Dudinak, Sandra Krogulski, Carlos O Garner, Jeffrey Francer, Sabine Luik, Jerry Stewart, Katrin Rupalla, Ginny Beakes-Read, Sean P Curtis, Jayne Ware, Kevin Carl, Nicole Mahoney, Donna Boyce, David C Isom, Michelle Rohrer, Fabio Bisordi, Peggy Lipp, Lina Aljuburi
{"title":"Accelerating the drug regulatory process through a federated cloud ecosystem.","authors":"Andrew S Robertson, Nahid Latif, Raymond C Votzmeyer, Natalie Tolli, Mark Taisey, Kevin Bugin, Kathy Williams, Michael Garvin, Max Wegner, Antoine Manson, Jennifer Dudinak, Sandra Krogulski, Carlos O Garner, Jeffrey Francer, Sabine Luik, Jerry Stewart, Katrin Rupalla, Ginny Beakes-Read, Sean P Curtis, Jayne Ware, Kevin Carl, Nicole Mahoney, Donna Boyce, David C Isom, Michelle Rohrer, Fabio Bisordi, Peggy Lipp, Lina Aljuburi","doi":"10.1038/d41573-026-00014-8","DOIUrl":"https://doi.org/10.1038/d41573-026-00014-8","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":" ","pages":""},"PeriodicalIF":101.8,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146106412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1038/d41573-026-00012-w
Mathias Baedeker, Clemens C. Möller
{"title":"2025 FDA approvals: volume maintained, but value remains below average","authors":"Mathias Baedeker, \u0000 Clemens C. Möller","doi":"10.1038/d41573-026-00012-w","DOIUrl":"10.1038/d41573-026-00012-w","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"91-91"},"PeriodicalIF":101.8,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-026-00012-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1038/d41573-026-00008-6
M. Teresa Villanueva
{"title":"Redirecting mast cells for antigen-specific cancer immunotherapy","authors":"M. Teresa Villanueva","doi":"10.1038/d41573-026-00008-6","DOIUrl":"10.1038/d41573-026-00008-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"96-96"},"PeriodicalIF":101.8,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1038/d41573-026-00009-5
Asher Mullard
{"title":"Lilly pays US$1.2 billion for Ventyx and its oral anti-inflammatories","authors":"Asher Mullard","doi":"10.1038/d41573-026-00009-5","DOIUrl":"10.1038/d41573-026-00009-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"90-90"},"PeriodicalIF":101.8,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1038/d41573-026-00010-y
Asher Mullard
{"title":"First antibody-mimetic adnectin nabs an FDA approval","authors":"Asher Mullard","doi":"10.1038/d41573-026-00010-y","DOIUrl":"10.1038/d41573-026-00010-y","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"89-89"},"PeriodicalIF":101.8,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1038/d41573-026-00005-9
Sarah Crunkhorn
{"title":"Boosting CAR T cell efficacy","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-026-00005-9","DOIUrl":"10.1038/d41573-026-00005-9","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"97-97"},"PeriodicalIF":101.8,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1038/d41573-026-00003-x
Alex Eccleston
{"title":"Innate immune receptor agonist for cancer immunotherapy","authors":"Alex Eccleston","doi":"10.1038/d41573-026-00003-x","DOIUrl":"10.1038/d41573-026-00003-x","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"25 2","pages":"94-94"},"PeriodicalIF":101.8,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145956139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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