NeuroImage最新文献_第10页

Dynamic cycles between brain states during creative storytelling

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-24 DOI: 10.1016/j.neuroimage.2025.121053

Xitong Liang , Mingnan Cai , Gaohan Jing , Chengming Zhang , Emily Sophia Nichols , Li Liu

Many theories suggest that creative thinking involves a dynamic transition between different mental states, yet empirical evidence supporting this notion remains scarce. The dual process model proposes that spontaneous thinking and deliberate thinking drive the dwell in and the transitions between different mental states during creative thinking, but there is a debate over whether the two types of thinking operate in parallel or in sequence. To address these gaps, we conducted a functional magnetic resonance imaging (fMRI) study in 41 college students during a creative storytelling task. We then compared the dynamic brain states in creative versus uncreative storytelling to identify key brain states associated with creative thinking. And we further performed correlation analysis between these key brain states with performance of various creative tasks, trying to link the key brain states with different cognitive processes. The results showed that two key brain states are associated with creative thinking, with one involving whole-brain synchronization and the other involving the synchronization of four networks, including the default mode network and the control network. The transition patterns between the key brain states provide tentative evidence for dynamic circulation between different mental states during creative storytelling. Using a deep learning approach, we demonstrate an alternating interaction between spontaneous and deliberate thinking, driving dwelling in and the transitions between different brain states. These findings deepen our understanding of the cognitive and neural mechanisms underlying creative thinking.

{"title":"Dynamic cycles between brain states during creative storytelling","authors":"Xitong Liang , Mingnan Cai , Gaohan Jing , Chengming Zhang , Emily Sophia Nichols , Li Liu","doi":"10.1016/j.neuroimage.2025.121053","DOIUrl":"10.1016/j.neuroimage.2025.121053","url":null,"abstract":"<div><div>Many theories suggest that creative thinking involves a dynamic transition between different mental states, yet empirical evidence supporting this notion remains scarce. The dual process model proposes that spontaneous thinking and deliberate thinking drive the dwell in and the transitions between different mental states during creative thinking, but there is a debate over whether the two types of thinking operate in parallel or in sequence. To address these gaps, we conducted a functional magnetic resonance imaging (fMRI) study in 41 college students during a creative storytelling task. We then compared the dynamic brain states in creative versus uncreative storytelling to identify key brain states associated with creative thinking. And we further performed correlation analysis between these key brain states with performance of various creative tasks, trying to link the key brain states with different cognitive processes. The results showed that two key brain states are associated with creative thinking, with one involving whole-brain synchronization and the other involving the synchronization of four networks, including the default mode network and the control network. The transition patterns between the key brain states provide tentative evidence for dynamic circulation between different mental states during creative storytelling. Using a deep learning approach, we demonstrate an alternating interaction between spontaneous and deliberate thinking, driving dwelling in and the transitions between different brain states. These findings deepen our understanding of the cognitive and neural mechanisms underlying creative thinking.</div></div>","PeriodicalId":19299,"journal":{"name":"NeuroImage","volume":"308 ","pages":"Article 121053"},"PeriodicalIF":4.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A joint three-plane physics-constrained deep learning based polynomial fitting approach for MR electrical properties tomography

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-23 DOI: 10.1016/j.neuroimage.2025.121054

Kyu-Jin Jung , Thierry G. Meerbothe , Chuanjiang Cui , Mina Park , Cornelis A.T. van den Berg , Stefano Mandija , Dong-Hyun Kim

Magnetic resonance electrical properties tomography can extract the electrical properties of in-vivo tissue. To estimate tissue electrical properties, various reconstruction algorithms have been proposed. However, physics-based reconstructions are prone to various artifacts such as noise amplification and boundary artifact. Deep learning-based approaches are robust to these artifacts but need extensive training datasets and suffer from generalization to unseen data. To address these issues, we introduce a joint three-plane physics-constrained deep learning framework for polynomial fitting MR-EPT by merging physics-based weighted polynomial fitting with deep learning. Within this framework, deep learning is used to discern the optimal polynomial fitting weights for a physics based polynomial fitting reconstruction on the complex

B_{1}^{+}

data. For the prediction of optimal fitting coefficients, three neural networks were separately trained on simulated heterogeneous brain models to predict optimal polynomial weighting parameters in three orthogonal planes. Then, the network weights were jointly optimized to estimate the polynomial weights in each plane for a combined conductivity reconstruction. Based on this physics-constrained deep learning approach, we achieved an improvement of conductivity estimation accuracy in comparison to a single plane estimation and a reduction of computational load. The results demonstrate that the proposed method based on 3D data exhibits superior performance in comparison to conventional polynomial fitting methods in terms of capturing anatomical detail and homogeneity. Crucially, in-vivo application of the proposed method showed that the method generalizes well to in-vivo data, without introducing significant errors or artifacts. This generalization makes the presented method a promising candidate for use in clinical applications.

{"title":"A joint three-plane physics-constrained deep learning based polynomial fitting approach for MR electrical properties tomography","authors":"Kyu-Jin Jung , Thierry G. Meerbothe , Chuanjiang Cui , Mina Park , Cornelis A.T. van den Berg , Stefano Mandija , Dong-Hyun Kim","doi":"10.1016/j.neuroimage.2025.121054","DOIUrl":"10.1016/j.neuroimage.2025.121054","url":null,"abstract":"<div><div>Magnetic resonance electrical properties tomography can extract the electrical properties of in-vivo tissue. To estimate tissue electrical properties, various reconstruction algorithms have been proposed. However, physics-based reconstructions are prone to various artifacts such as noise amplification and boundary artifact. Deep learning-based approaches are robust to these artifacts but need extensive training datasets and suffer from generalization to unseen data. To address these issues, we introduce a joint three-plane physics-constrained deep learning framework for polynomial fitting MR-EPT by merging physics-based weighted polynomial fitting with deep learning. Within this framework, deep learning is used to discern the optimal polynomial fitting weights for a physics based polynomial fitting reconstruction on the complex <span><math><msubsup><mi>B</mi><mn>1</mn><mo>+</mo></msubsup></math></span> data. For the prediction of optimal fitting coefficients, three neural networks were separately trained on simulated heterogeneous brain models to predict optimal polynomial weighting parameters in three orthogonal planes. Then, the network weights were jointly optimized to estimate the polynomial weights in each plane for a combined conductivity reconstruction. Based on this physics-constrained deep learning approach, we achieved an improvement of conductivity estimation accuracy in comparison to a single plane estimation and a reduction of computational load. The results demonstrate that the proposed method based on 3D data exhibits superior performance in comparison to conventional polynomial fitting methods in terms of capturing anatomical detail and homogeneity. Crucially, in-vivo application of the proposed method showed that the method generalizes well to in-vivo data, without introducing significant errors or artifacts. This generalization makes the presented method a promising candidate for use in clinical applications.</div></div>","PeriodicalId":19299,"journal":{"name":"NeuroImage","volume":"307 ","pages":"Article 121054"},"PeriodicalIF":4.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demystifying authenticity: Behavioral and neurophysiological signatures of self-positivity for authentic and presented selves

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-23 DOI: 10.1016/j.neuroimage.2025.121046

Chengli Huang , Constantine Sedikides , Douglas J. Angus , William E. Davis , James W. Butterworth , Alexiss Jeffers , Rebecca Schlegel , Nicholas J. Kelley

Authenticity has captivated scholars. But what is it? An emerging view considers it exaggerated favorability (self-enhancement), whereas traditional views regard it as self-accuracy and self-consistency. We tested these theoretical views by contrasting the authentic self with the presented self, a highly desirable representation. Behaviorally, participants ascribed less positivity to the authentic self: They endorsed more negative traits and were faster to admit having them; also, they endorsed fewer positive traits and were slower to admit having them. Neurally, participants manifested preferential processing of threatening information (P1), followed by preferential processing of favorable information (N170), about the presented self (than authentic self), indicating its brittleness. At a later stage (LPP), participants engaged in more elaborate processing of threatening and favorable information about the authentic self, indicating its subjective importance. Authenticity, albeit mostly positive, allows room for negativity.

{"title":"Demystifying authenticity: Behavioral and neurophysiological signatures of self-positivity for authentic and presented selves","authors":"Chengli Huang , Constantine Sedikides , Douglas J. Angus , William E. Davis , James W. Butterworth , Alexiss Jeffers , Rebecca Schlegel , Nicholas J. Kelley","doi":"10.1016/j.neuroimage.2025.121046","DOIUrl":"10.1016/j.neuroimage.2025.121046","url":null,"abstract":"<div><div>Authenticity has captivated scholars. But what is it? An emerging view considers it exaggerated favorability (self-enhancement), whereas traditional views regard it as self-accuracy and self-consistency. We tested these theoretical views by contrasting the authentic self with the presented self, a highly desirable representation. Behaviorally, participants ascribed less positivity to the authentic self: They endorsed more negative traits and were faster to admit having them; also, they endorsed fewer positive traits and were slower to admit having them. Neurally, participants manifested preferential processing of threatening information (P1), followed by preferential processing of favorable information (N170), about the presented self (than authentic self), indicating its brittleness. At a later stage (LPP), participants engaged in more elaborate processing of threatening and favorable information about the authentic self, indicating its subjective importance. Authenticity, albeit mostly positive, allows room for negativity.</div></div>","PeriodicalId":19299,"journal":{"name":"NeuroImage","volume":"307 ","pages":"Article 121046"},"PeriodicalIF":4.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Event-related theta synchronization over sensorimotor areas differs between younger and older adults and is related to bimanual motor control

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-23 DOI: 10.1016/j.neuroimage.2025.121032

Andreas Wulff-Abramsson , Ana Zvornik , Keenie Ayla Andersen , Yan Yang , Mikael Novén , Jesper Lundbye-Jensen , Leo Tomasevic , Anke Ninija Karabanov

When engaged in dynamic or continuous movements, action initiation involves modifying an ongoing motor program rather than initiating it from rest. Event-related theta synchronization over sensorimotor areas is a neurophysiological marker for modifying motor programs. We used electroencephalography (EEG) to examine how task complexity and age affect event-related synchronization (ERS) in the theta band during a dynamic bimanual, visuomotor pinch force task. Older (mean age = 68) and younger (mean age = 26) participants performed symmetric (SYM) and asymmetric (ASYM) bimanual pinch force adjustments. Trials began with a visually cued contraction from a baseline force to a novel target force (P1). Force had to be maintained at the target until a visually cued return to the familiar baseline (P2). Older adults reacted slower across task conditions, and their accuracy decreased more when shifting from the SYM to the ASYM condition. Older adults also displayed lower theta ERS across conditions. Additionally, older adults were not able to modulate theta expression based on whether a force change was initiated to a novel target or back to baseline. Younger adults showed significantly stronger theta ERS after P1-cues compared to P2-cues, while the theta response to P1 and P2 cues was not different in older adults. Older adults also showed stronger lateralization, displaying higher theta ERS over the dominant motor cortex. Finally, event-related theta synchronization appeared to be behaviorally relevant across groups and correlated with task performance. Together, the results show that theta ERS over sensorimotor areas is a strong, age-sensitive marker of dynamic pinch force adjustments showing an age-related reduction in specificity with reduced context-dependent modulations and more imbalanced bimanual activation.

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引用次数: 0

Volumetric alterations in auditory and visual subcortical nuclei following perinatal deafness in felines

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-23 DOI: 10.1016/j.neuroimage.2025.121047

Alessandra Sacco , Stephen G. Gordon , Stephen G. Lomber

In response to sensory deprivation, the brain adapts to efficiently navigate a modified perceptual environment through a process referred to as compensatory crossmodal plasticity, allowing the remaining senses to repurpose deprived regions and networks. A mechanism that has been proposed to contribute to this plasticity involves adaptations within subcortical nuclei that trigger cascading effects throughout the brain. The current study uses 7T MRI to investigate the effect of perinatal deafness on the volumes of subcortical structures in felines, focusing on key sensory nuclei within the brainstem and thalamus. Using both ROI-based and morphometric approaches, the regional macrostructure of four auditory and two visual nuclei were studied, as well as the corresponding volumetric asymmetries within and across groups. In the auditory pathway, significant bilateral volumetric reductions were revealed within the lower-level structures (cochlear nucleus, superior olivary complex, and inferior colliculus), alongside a shrinkage of solely the left medial geniculate body. Within the visual pathway, a significant bilateral volumetric reduction was found in the lateral geniculate nucleus, with the superior colliculus largely unaffected. These regional alterations, along with an extensive loss of volume throughout the brainstem of deprived cats, were attributed to disuse-driven atrophy corresponding to evolved functional demands reflective of a modified perceptual environment. Furthermore, the left-right volumetric symmetries of the control subcortex were preserved following deafness. Overall, the current study reinforces the notion that subcortical structures likely contribute to compensatory crossmodal plasticity prior to cortical processing, and that these deafness-induced adaptations appear to be influenced by both the level of the affected structure within its respective sensory processing hierarchy and the specifics of its afferent profile.

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引用次数: 0

Positive resonance: Successful interpersonal emotion regulation facilitated relationship closeness by enhanced inter-brain synchronization

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-21 DOI: 10.1016/j.neuroimage.2025.121042

Tongtong Zhu , Xiaoxuan Zhang , Luyao Jin , Linzi Wang , Yanmei Wang

Interpersonal emotion regulation (IER) refers to the dynamic process where a regulator employs specific strategies to alleviate a target's distress. It remains unclear whether successful IER could facilitate interpersonal relationship closeness (IRC). The present study aimed to explore whether successful IER, based on two typical strategies—cognitive reappraisal (CR) and expressive suppression (ES)—for down-regulating the target's negative emotions, could enhance IRC among friend dyads, and to identify the underlying neural correlates of this process using functional near-infrared spectroscopy system. Seventy-four female dyads (friends) were randomly assigned to one of two strategy groups (CR vs. ES), with one participant as the target and the other as the regulator. Our findings revealed that both strategies have down-regulated the target's negative emotions, however, CR strategy was associated with more successful IER outcomes (more improvement of the targets’ negative emotions; higher IRC) than ES strategy. IER recruited the enhanced interpersonal brain synchronization (IBS) of the prefrontal and temporal areas among friend dyads. CR strategy recruited higher IBS of the above-mentioned brain networks than ES strategy in down-regulating the target's sadness, and the reversed IBS pattern was found in down-regulating the target's anger, inferring that CR was more successive in IER of sadness, and ES was more effective in IER of anger. The increased IBS pattern of these brain regions played a mediational role between the effectiveness of down-regulating targets’ negative emotions and the increment of IRC. Our findings revealed a neural coupling mechanism through which successful IER fostered supportive social bonds.

{"title":"Positive resonance: Successful interpersonal emotion regulation facilitated relationship closeness by enhanced inter-brain synchronization","authors":"Tongtong Zhu , Xiaoxuan Zhang , Luyao Jin , Linzi Wang , Yanmei Wang","doi":"10.1016/j.neuroimage.2025.121042","DOIUrl":"10.1016/j.neuroimage.2025.121042","url":null,"abstract":"<div><div>Interpersonal emotion regulation (IER) refers to the dynamic process where a regulator employs specific strategies to alleviate a target's distress. It remains unclear whether successful IER could facilitate interpersonal relationship closeness (IRC). The present study aimed to explore whether successful IER, based on two typical strategies—cognitive reappraisal (CR) and expressive suppression (ES)—for down-regulating the target's negative emotions, could enhance IRC among friend dyads, and to identify the underlying neural correlates of this process using functional near-infrared spectroscopy system. Seventy-four female dyads (friends) were randomly assigned to one of two strategy groups (CR vs. ES), with one participant as the target and the other as the regulator. Our findings revealed that both strategies have down-regulated the target's negative emotions, however, CR strategy was associated with more successful IER outcomes (more improvement of the targets’ negative emotions; higher IRC) than ES strategy. IER recruited the enhanced interpersonal brain synchronization (IBS) of the prefrontal and temporal areas among friend dyads. CR strategy recruited higher IBS of the above-mentioned brain networks than ES strategy in down-regulating the target's sadness, and the reversed IBS pattern was found in down-regulating the target's anger, inferring that CR was more successive in IER of sadness, and ES was more effective in IER of anger. The increased IBS pattern of these brain regions played a mediational role between the effectiveness of down-regulating targets’ negative emotions and the increment of IRC. Our findings revealed a neural coupling mechanism through which successful IER fostered supportive social bonds.</div></div>","PeriodicalId":19299,"journal":{"name":"NeuroImage","volume":"307 ","pages":"Article 121042"},"PeriodicalIF":4.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain connectivity for constructing new face representations in typical adults versus a prosopagnosic patient

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-20 DOI: 10.1016/j.neuroimage.2025.121039

Ela I. Olivares , Jorge F. Bosch-Bayard , Ana S. Urraca , Alba Jiménez-Bascuñán , Rolando J. Biscay , Jaime Iglesias

Will our brains get to know a new face better if we look at its external features first? Here we offer neurophysiological evidence of the relevance of external versus internal facial features for constructing new face representations, by contrasting successful face processing with a prototypical case of face agnosia. A woman with acquired prosopagnosia (E.C.) and 14 age-matched typical participants (7 women) were exposed to a face-feature matching task. External (E), internal (I) features, and whole target faces of unknown individuals (from an IdentiKit gallery) were displayed according to two different sequences: E

\to

I

\to

whole faces, or I

\to

E

\to

whole faces. Then, we studied the induced EEG activity using ‘isolated effective coherence’ to analyse the intracortical causal information flow among face-sensitive nodes. Initial presentation of external features (E before I), when compared to internal ones, triggered connections encompassing extensively the right-hemisphere face processing pathway [from posterior visual cortices for initial structural analysis, towards both intermediate (occipitotemporal) and high-level (prefrontal) relay stations], in which face-identity is thought to emerge progressively. Also, whereas exposure to internal features as second stimulus seemed to demand some sort of basic visual processing, external features triggered again more widespread and integrative connections. Connections for whole faces closing the E-I sequence resembled those for external features initiating the same sequence. Meanwhile, the predominant connections for whole faces completing the I-E sequence were more restricted to specific brain areas, with relevant prefrontal activity and a few connected nodes in right posterior regions, suggesting high attentional load plus initial and intermediate processing of face identity. Interestingly, the pattern of connections that distinguished typical participants from E.C. in the I-E sequence was the recruitment of left posterior visual regions, presumably underlying analytical subroutines for structural encoding of facial stimuli. These findings support that initial exposure to external features, followed by internal ones, provides the best visual cue to acquire new face configurations. Nevertheless, in case of face agnosia after right posterior damage, relying preferentially on internal features and left hemisphere specialized subroutines might be an alternative for cognitive training.

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引用次数: 0

The neural activity of auditory conscious perception 听觉意识知觉的神经活动

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-19 DOI: 10.1016/j.neuroimage.2025.121041

Kate L. Christison-Lagay , Aya Khalaf , Noah C. Freedman , Christopher Micek , Sharif I. Kronemer , Mariana M. Gusso , Lauren Kim , Sarit Forman , Julia Ding , Mark Aksen , Ahmad Abdel-Aty , Hunki Kwon , Noah Markowitz , Erin Yeagle , Elizabeth Espinal , Jose Herrero , Stephan Bickel , James Young , Ashesh Mehta , Kun Wu , Hal Blumenfeld

Although recent work has made headway in understanding the neural temporospatial dynamics of conscious perception, much of that work has focused on visual paradigms. To determine whether there are shared mechanisms for perceptual consciousness across sensory modalities, here we test within the auditory domain. Participants completed an auditory threshold task while undergoing intracranial electroencephalography. Recordings from >2,800 grey matter electrodes were analyzed for broadband gamma power (a range which reflects local neural activity). For perceived trials, we find nearly simultaneous activity in early auditory regions, the right caudal middle frontal gyrus, and the non-auditory thalamus; followed by a wave of activity that sweeps through auditory association regions into parietal and frontal cortices. For not perceived trials, significant activity is restricted to early auditory regions. These findings show the cortical and subcortical networks involved in auditory perception are similar to those observed with vision, suggesting shared mechanisms for conscious perception.

虽然最近的工作在理解意识知觉的神经时空动力学方面取得了进展，但大部分工作都集中在视觉范式上。为了确定是否存在跨感觉模式的知觉意识共享机制，这里我们在听觉领域进行测试。参与者在接受颅内脑电图检查的同时完成了一个听觉阈值任务。研究人员分析了bbb2,800个灰质电极的宽带伽马功率（反映局部神经活动的范围）记录。在感知试验中，我们发现早期听觉区域、右侧尾侧额叶中回和非听觉丘脑几乎同时活动；接着是一波活动，穿过听觉关联区，进入顶叶和额叶皮层。对于非感知试验，显著活动仅限于早期听觉区域。这些发现表明，参与听觉感知的皮层和皮层下网络与观察到的视觉网络相似，表明有意识感知的机制是相同的。

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引用次数: 0

Corrigendum to “Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner” [NeuroImage 305 (2025) 120995] “脓毒症以性别依赖的方式调节感觉运动皮层和纹状体区域的功能连通性”[NeuroImage 305(2025) 120995]的更正。

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-19 DOI: 10.1016/j.neuroimage.2025.121025

Quan Vo , Zachary D. Simon , Gwoncheol Park , Dina C Nacionales , Carmelina Gorski , Evan L Barrios , Gemma Casadesus , Philip A Efron , Lyle L Moldawer , Ravinder Nagpal , Paramita Chakrabarty , Marcelo Febo

引用次数: 0

Emotion processing of facial affect expression in patients with somatic symptom disorder with predominant pain–An EEG-study 以疼痛为主的躯体症状障碍患者面部情感表达的情绪加工-脑电图研究。

IF 4.7 2区医学 Q1 NEUROIMAGING

NeuroImage

Pub Date : 2025-01-17 DOI: 10.1016/j.neuroimage.2025.121036

Eva Metzen , Mahboobeh Dehghan Nayyeri , Ralf Schäfer , Ulrike Dinger , Matthias Franz , Rüdiger Seitz , Jörg Rademacher

Despite their high prevalence, somatoform pain disorders are often not recognized early enough, not diagnosed reliably enough and not treated appropriately. Patients often experience a high level of suffering and the feeling of not being understood. For the medical care system, the symptoms represent a diagnostic and therapeutic challenge. Having the aim to get a better understanding of the disease, this study investigated the patients' emotion processing. In addition, the influence of surgical masks on facial affect processing was investigated, which has become more important since the onset of the Covid-19. The study involved an electroencephalogram (EEG) experimental paradigm extracting visual event-related potentials (vERP) evoked by emotional faces with and without surgical masks. Overall, the results of the face-related vERP indicate that the healthy control participants process the different emotional faces in a differentiated way. This can be seen from the fact that in this group the amplitudes of the vERP differ according to the different affects. In contrast, the patient group does not show any affect-specific potential differences in the vERP components. Besides, in healthy control participants, masks appear to limit the brain's ability to process emotions by hiding important facial information. Patients do not show any differences in the way they process images with and without masks, which suggests that patients generally process this content more rudimentary.

尽管发病率很高，但躯体形式疼痛疾病往往不能及早发现，诊断不够可靠，治疗也不够适当。患者通常会经历高度的痛苦和不被理解的感觉。对于医疗保健系统，这些症状代表了诊断和治疗的挑战。为了更好地了解这种疾病，本研究调查了患者的情绪处理。此外，我们还调查了医用口罩对面部情绪处理的影响，这在新冠肺炎爆发后变得更加重要。本研究采用脑电图（EEG）实验范式，提取带口罩和不带口罩的情绪化面孔所诱发的视觉事件相关电位（vERP）。总体而言，与面部相关的vERP结果表明，健康对照组的参与者对不同情绪面孔的处理方式是不同的。这可以从以下事实看出：在这一组中，根据不同的影响，vERP的幅度不同。相比之下，患者组在vERP成分中没有表现出任何特定影响的潜在差异。此外，在健康的对照组参与者中，面具似乎通过隐藏重要的面部信息来限制大脑处理情绪的能力。患者在处理带口罩和不带口罩的图像时没有表现出任何差异，这表明患者通常处理这些内容更初级。

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引用次数: 0