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Estimating resting metabolic rate in older Chinese adults:A community-based study integrating dietary predictors 估计中国老年人静息代谢率:一项结合饮食预测因子的社区研究
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-12-05 DOI: 10.1016/j.nut.2025.113054
Qi Dong , Lu Wu , Jiao Liu , Danye Niu , Li Wang , Ning Li , Yanmin Zheng , Lei Ding , Yating Ma , Bo Wang , Ming Zhou

Objectives

Resting metabolic rate (RMR), which accounts for 60% to 75% of total daily energy expenditure, is critical for formulating appropriate nutrition plans and for the prevention of overweight and obesity. The aim of this study was to systematically consider dietary and other factors affecting RMR and propose a predictive equation for the older adults.

Methods

A total of 373 elderly participants aged 60 to 89 years (205 males) were included in this study. RMR was measured using indirect calorimetry (IC). One-on-one measurements and questionnaires were used to collect data on height, weight, waist circumference, physical activity, sleep duration, and food consumption frequency. Multiple linear regression was used to construct models, which were compared with existing equations.

Results

The RMR values of the study participants ranged from 652 to 1635 kcal/d. The average RMR for males and fe-males was 1175.3 ± 167.9 kcal/d and 1001.5 ± 159.7 kcal/d, respectively. Two models were constructed using multiple regression, with variables including sex, weight, fat-free mass (FFM), fat mass (FM), age, and animal offal consumption. The newly established formula demonstrated better accuracy than the other formulas based on comparisons of biases, Lin’s Concordance Correlation Coefficient (CCC), root mean square errors (RMSE), accuracies, and Bland-Altman plots.

Conclusion

This study developed new RMR predictive equations for individuals aged 60 and above. The newly developed equations in-corporates animal offal consumption and demonstrates higher predictive performance compared to other equations.
静息代谢率(RMR)占每日总能量消耗的60%至75%,对于制定适当的营养计划和预防超重和肥胖至关重要。本研究的目的是系统地考虑饮食和其他影响RMR的因素,并提出老年人RMR的预测方程。方法本研究共纳入373例60 ~ 89岁的老年人,其中男性205例。RMR采用间接量热法(IC)测定。采用一对一测量和问卷调查收集身高、体重、腰围、体力活动、睡眠时间和食物消耗频率等数据。采用多元线性回归建立模型,并与已有方程进行比较。结果研究参与者的RMR值为652 ~ 1635 kcal/d。雄性和雌性的平均RMR分别为1175.3±167.9 kcal/d和1001.5±159.7 kcal/d。以性别、体重、无脂质量(FFM)、脂肪质量(FM)、年龄和动物内脏食用量为变量,采用多元回归方法构建2个模型。基于偏倚、Lin’s Concordance Correlation Coefficient (CCC)、均方根误差(RMSE)、准确度和Bland-Altman图的比较,新建立的公式比其他公式具有更好的准确性。结论本研究为60岁及以上人群建立了新的RMR预测方程。与其他方程相比,新开发的方程包含了动物内脏消耗,并显示出更高的预测性能。
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引用次数: 0
Video gaming linked to unhealthy diet, poor sleep quality and lower physical activity levels in Australian University students 视频游戏与澳大利亚大学生的不健康饮食、睡眠质量差和体育锻炼水平低有关。
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-12-05 DOI: 10.1016/j.nut.2025.113051
Thanaporn Kaewpradup Ph.D. , Svetlana Deric M.Sc. , Hannah Velure Uren Ph.D. , Van Hoang Nguyen M.D. , Leticia Radin Pereira Ph.D. , Ranil Coorey Ph.D. , Jonathan C.K. Wells Ph.D. , Sirichai Adisakwattana Ph.D. , Blossom C.M. Stephan Ph.D. , Mario Siervo Ph.D.

Objectives

Video gaming is highly prevalent among university students, yet its health associations remain poorly understood. This study examined relationships between video gaming frequency and health in Australian university students.

Methods

A cross-sectional survey of 317 Western Australian university students assessed gaming habits, diet quality (Diet Quality Tool), physical activity (International Physical Activity Questionnaire), sleep quality (Pittsburgh Sleep Quality Index), eating behaviors (Three-Factor Eating Questionnaire), and perceived stress (Perceived Stress Scale). Participants were categorized into tertiles based on gaming frequency (low [0–5 h/wk], moderate [6–10 h/wk], and high [>10 h/wk]).

Results

High-frequency gamers had significantly poorer diet quality scores (median 45.0 versus 50.0, P < 0.001), higher BMI (median 26.3 versus 22.2 kg/m², P < 0.001), and worse sleep quality (PSQI score 7.0 versus 6.0, P < 0.001) compared to low-frequency gamers. Correlation analyses confirmed these associations in which gaming frequency negatively correlated with diet quality (r = −0.26, P < 0.001) and physical activity (r = −0.13, P = 0.03) and positively correlated with BMI (r = 0.38, P < 0.001). Multiple regression analysis revealed total gaming hours independently predicted poorer diet quality (β = −0.16, P = 0.02) after controlling for demographic and lifestyle factors.

Conclusions

Higher video gaming frequency was associated with poorer diet quality and increased BMI among university students. These findings suggest excessive gaming may contribute to adverse health outcomes. Public health interventions targeting excessive or high gaming levels and promoting healthy lifestyle habits in university populations are warranted.
目标:电子游戏在大学生中非常普遍,但其与健康的关系却鲜为人知。这项研究调查了澳大利亚大学生玩电子游戏的频率与健康之间的关系。方法:对317名西澳大利亚大学生进行横断面调查,评估游戏习惯、饮食质量(饮食质量工具)、体育活动(国际体育活动问卷)、睡眠质量(匹兹堡睡眠质量指数)、饮食行为(三因素饮食问卷)和感知压力(感知压力量表)。参与者根据游戏频率分为低(0-5小时/周)、中(6-10小时/周)和高(10 -10小时/周)。结果:与低频玩家相比,高频玩家的饮食质量得分明显较低(中位数为45.0比50.0,P < 0.001), BMI较高(中位数为26.3比22.2 kg/m²,P < 0.001),睡眠质量较差(PSQI得分7.0比6.0,P < 0.001)。相关分析证实,游戏频率与饮食质量(r = -0.26, P < 0.001)和身体活动(r = -0.13, P = 0.03)呈负相关,与BMI呈正相关(r = 0.38, P < 0.001)。多元回归分析显示,在控制人口统计学和生活方式因素后,总游戏时间独立预测较差的饮食质量(β = -0.16, P = 0.02)。结论:大学生玩电子游戏的频率越高,饮食质量越差,身体质量指数越高。这些发现表明,过度的游戏可能会导致不良的健康结果。针对大学人群过度或高游戏水平的公共卫生干预措施和促进健康的生活习惯是必要的。
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引用次数: 0
Effect of Mediterranean diet adherence during the third trimester of pregnancy on maternal and newborn health outcomes. 妊娠晚期坚持地中海饮食对孕产妇和新生儿健康结局的影响
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-12-01 Epub Date: 2025-07-13 DOI: 10.1016/j.nut.2025.112909
Jiyan Aslan Ceylan

Objectives: The aim of this study was to explore the impact of Mediterranean diet (MD) adherence during the third trimester of pregnancy on both maternal and newborn health, focusing on birth weight, cranial perimeter, and maternal biochemical markers.

Methods: This cross-sectional study was conducted with 300 volunteer pregnant women. Maternal sociodemographic, nutritional, and biochemical data were collected before delivery (weeks 27-41 of pregnancy), while newborn anthropometric measurements were obtained within 2 d of birth. MD adherence was assessed using the KIDMED index, classifying participants into low, moderate, or optimal adherence groups.

Results: 54.0% of pregnant women had very low, 27.7% moderate, and 18.3% optimal adherence to MD. Maternal urea, free T4, hemoglobin, and vitamin B12 levels were higher in the moderate adherence group, while folate and vitamin D levels were lower in the very low adherence group (P ≤ 0.05). Logistic regression analysis indicated that maternal adherence to MD was not significantly associated with birth weight (P = 0.10, AOR = 1.082) and cranial perimeter (P = 0.63, AOR = 1.016). Pregnancy weight gain was significantly associated with a lower risk of low birth weight (P < 0.01, AOR = 2.312), and folate levels showed a borderline significant association (P = 0.05, AOR = 0.921). Factors influencing cranial perimeter included prepregnancy body mass index (P = 0.05), weight gain (P < 0.01, AOR = 2.007), folate (P = 0.04, AOR = 0.947), and vitamin B12 levels (P < 0.01, AOR = 0.996).

Conclusions: MD adherence did not directly impact neonatal anthropometric outcomes, but its effect on maternal biochemical markers, lifestyle and nutritional habits suggests potential benefits for maternal health.

目的:本研究的目的是探讨妊娠晚期地中海饮食(MD)依从性对孕产妇和新生儿健康的影响,重点关注出生体重、颅围和母体生化指标。方法:对300名自愿怀孕妇女进行横断面研究。在分娩前(怀孕27-41周)收集产妇的社会人口学、营养和生化数据,并在出生后2天内获得新生儿的人体测量数据。使用KIDMED指数评估MD依从性,将参与者分为低、中等或最佳依从性组。结果:54.0%的孕妇极低、27.7%为中等、18.3%为最佳MD依从性。中度依从组孕妇尿素、游离T4、血红蛋白、维生素B12水平较高,极低依从组孕妇叶酸、维生素D水平较低(P≤0.05)。Logistic回归分析显示,产妇依从MD与出生体重(P = 0.10, AOR = 1.082)和颅围(P = 0.63, AOR = 1.016)无显著相关。妊娠期体重增加与低出生体重风险显著相关(P < 0.01, AOR = 2.312),叶酸水平与低出生体重风险显著相关(P = 0.05, AOR = 0.921)。影响颅围的因素包括孕前体重指数(P = 0.05)、体重增加(P < 0.01, AOR = 2.007)、叶酸(P = 0.04, AOR = 0.947)、维生素B12水平(P < 0.01, AOR = 0.996)。结论:MD依从性并不直接影响新生儿的人体测量结果,但其对产妇生化指标、生活方式和营养习惯的影响表明其对产妇健康有潜在的益处。
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引用次数: 0
Beverage consumption and nutritional status of children aged 2-6, and their mothers' attitude toward healthy nutrition. 2-6岁儿童的饮料消费、营养状况及母亲对健康营养的态度
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-12-01 Epub Date: 2025-07-14 DOI: 10.1016/j.nut.2025.112907
Merve Macin Yildiz, Elif Bilsin Kocamaz

Objectives: The aim of this research was to examine the beverage consumption and nutritional status of children aged 2-6 y, as well as the attitudes of their mothers toward healthy nutrition.

Methods: The study was conducted using a descriptive and cross-sectional method. It was carried out in 15 Family Health Centers, randomly selected from a total of 153 centers located in the central districts of Şahinbey and Şehitkamil in Gaziantep, between May 2023 and January 2024. The sample size was determined using a power analysis program, which indicated that at least 400 mothers were needed. However, to account for potential data loss, 507 mothers who met the inclusion criteria and agreed to participate were included in the study. Data were collected using the Mother and Child Identification Form, the Children's Beverage Consumption Form, and the Attitude Scale for Healthy Nutrition (ASHN).

Results: The findings showed that 96.3% of the children had weight-for-age Z-scores, 99% had height-for-age Z-scores, and 95.4% had BMI for-age Z-scores within the normal range (between -2 and +2). Among beverages consumed within a 24-h period, milk was the most frequently consumed after water. The mean total score on the ASHN was 70.64 ± 0.28, indicating that mothers had a high level of positive attitudes toward healthy nutrition.

Conclusions: Nursing interventions play a key role in helping children develop healthy eating habits and in preventing nutrition-related health problems in the future.

目的:本研究旨在了解2 ~ 6岁儿童的饮料消费与营养状况,以及其母亲对健康营养的态度。方法:采用描述性和横断面法进行研究。该调查于2023年5月至2024年1月在加济安泰普Şahinbey和Şehitkamil中心区的153个中心中随机抽取的15个家庭保健中心开展。样本量是通过功率分析程序确定的,这表明至少需要400名母亲。然而,考虑到潜在的数据丢失,507名符合纳入标准并同意参与研究的母亲被纳入研究。采用《母婴识别表》、《儿童饮料消费表》和《健康营养态度量表》进行数据收集。结果:96.3%的儿童年龄体重z -score, 99%的儿童年龄身高z -score, 95.4%的儿童年龄BMI z -score在正常范围内(-2 ~ +2)。在24小时内饮用的饮料中,牛奶是仅次于水的最常饮用饮料。ASHN的平均总分为70.64±0.28,表明母亲对健康营养有较高的积极态度。结论:护理干预在帮助儿童养成健康的饮食习惯和预防未来营养相关健康问题方面发挥着关键作用。
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引用次数: 0
Impact of complementary feeding methods on infant nutritional status: A randomized clinical trial. 辅助喂养方式对婴儿营养状况的影响:一项随机临床试验。
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-12-01 Epub Date: 2025-07-11 DOI: 10.1016/j.nut.2025.112908
Cátia Regina Ficagna, Elma Izze da Silva Magalhães, Abby Branchini Chacón, Paula Ruffoni Moreira, Renata Oliveira Neves, Leandro Meirelles Nunes, Juliana Rombaldi Bernardi

Objective: To evaluate the impact of different CF methods on infant anthropometric outcomes at 9 and 12 mo.

Methods: This randomized clinical trial (Brazilian Clinical Trials Registry-ReBEC: RBR-229SCM N° U1111-1226-9516) included mother-infant pairs recruited at 5.5 mo in Porto Alegre, Brazil. Participants were randomized to one of three CF methods: food introduction through parent-led weaning (PLW), baby-led introduction to solids (BLISS), or mixed. At 5.5 mo, mothers attended a workshop led by nutritionists and speech therapists with verbal and written guidance on the assigned CF method (PLW: n = 46; BLISS: n = 47; Mixed: n = 46). Infants were followed up at 9 and 12 mo, and weight and length measurements were taken. Primary outcomes were z-scores of the anthropometric indexes weight-for-age, length-for-age, weight-for-length, and body mass index (BMI)-for-age. Secondary outcomes were nutritional status classifications based on these indices.

Results: Of the 140 mother-infant pairs who participated, anthropometric data were collected from 130 children at 9 mo and 131 at 12 mo. Children in the BLISS group had lower mean BMI-for-age z-scores at 12 mo than those in the PLW group (adjusted β: -0.53; 95% CI: -1.03 to -0.03; P = 0.035). The mixed method reduced the risk of overweight/obesity across 9-12 mo (adjusted HR: 0.11; 95% CI: 0.01 to 0.97; P = 0.048). No statistically significant associations were observed for the other outcomes.

Conclusion: Infant-guided CF methods were associated with favorable short-term anthropometric outcomes; however, further studies with longer follow-up and larger sample sizes are needed to confirm their role in obesity prevention.

目的:评估不同CF方法对婴儿9月和12月时人体测量结果的影响。方法:该随机临床试验(巴西临床试验注册中心:RBR-229SCM N°U1111-1226-9516)在巴西阿雷格里港招募了5.5月时的母婴对。参与者被随机分配到三种CF方法中的一种:通过父母主导的断奶(PLW),婴儿主导的固体(BLISS)或混合引入食物。在5.5个月时,母亲们参加了由营养学家和语言治疗师主持的研讨会,并就指定的CF方法获得口头和书面指导(PLW: n = 46;BLISS: n = 47;混合:n = 46)。婴儿在9个月和12个月时随访,并测量体重和长度。主要结局是年龄体重、年龄长度、身高体重和年龄体重指数(BMI)的z分数。次要结局是基于这些指标的营养状况分类。结果:在参与研究的140对母婴中,收集了130名9月龄儿童和131名12月龄儿童的人体测量数据。BLISS组儿童在12月龄时的平均bmi -年龄z分数低于PLW组(调整后的β: -0.53;95% CI: -1.03 ~ -0.03;P = 0.035)。混合方法降低了9-12个月内超重/肥胖的风险(调整后HR: 0.11;95% CI: 0.01 ~ 0.97;P = 0.048)。其他结果未观察到统计学上显著的关联。结论:婴儿引导的CF方法与良好的短期人体测量结果相关;然而,需要更长的随访时间和更大样本量的进一步研究来证实它们在预防肥胖中的作用。
{"title":"Impact of complementary feeding methods on infant nutritional status: A randomized clinical trial.","authors":"Cátia Regina Ficagna, Elma Izze da Silva Magalhães, Abby Branchini Chacón, Paula Ruffoni Moreira, Renata Oliveira Neves, Leandro Meirelles Nunes, Juliana Rombaldi Bernardi","doi":"10.1016/j.nut.2025.112908","DOIUrl":"10.1016/j.nut.2025.112908","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of different CF methods on infant anthropometric outcomes at 9 and 12 mo.</p><p><strong>Methods: </strong>This randomized clinical trial (Brazilian Clinical Trials Registry-ReBEC: RBR-229SCM N° U1111-1226-9516) included mother-infant pairs recruited at 5.5 mo in Porto Alegre, Brazil. Participants were randomized to one of three CF methods: food introduction through parent-led weaning (PLW), baby-led introduction to solids (BLISS), or mixed. At 5.5 mo, mothers attended a workshop led by nutritionists and speech therapists with verbal and written guidance on the assigned CF method (PLW: n = 46; BLISS: n = 47; Mixed: n = 46). Infants were followed up at 9 and 12 mo, and weight and length measurements were taken. Primary outcomes were z-scores of the anthropometric indexes weight-for-age, length-for-age, weight-for-length, and body mass index (BMI)-for-age. Secondary outcomes were nutritional status classifications based on these indices.</p><p><strong>Results: </strong>Of the 140 mother-infant pairs who participated, anthropometric data were collected from 130 children at 9 mo and 131 at 12 mo. Children in the BLISS group had lower mean BMI-for-age z-scores at 12 mo than those in the PLW group (adjusted β: -0.53; 95% CI: -1.03 to -0.03; P = 0.035). The mixed method reduced the risk of overweight/obesity across 9-12 mo (adjusted HR: 0.11; 95% CI: 0.01 to 0.97; P = 0.048). No statistically significant associations were observed for the other outcomes.</p><p><strong>Conclusion: </strong>Infant-guided CF methods were associated with favorable short-term anthropometric outcomes; however, further studies with longer follow-up and larger sample sizes are needed to confirm their role in obesity prevention.</p>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"140 ","pages":"112908"},"PeriodicalIF":3.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on “Nutritional outcomes in people with cystic fibrosis receiving elexacaftor/tezacaftor/ivacaftor: A 24-month real-world study” 对“接受elexaftor /tezacaftor/ivacaftor治疗的囊性纤维化患者的营养结果:一项为期24个月的现实世界研究”的评论。
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-11-27 DOI: 10.1016/j.nut.2025.113048
S. Dhanya Dedeepya MD, Vaishali Goel PhD, Nivedita Nikhil Desai MD
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引用次数: 0
Can food choices be associated with nutritional status and atopic dermatitis severity in children and adolescents? 儿童和青少年的食物选择是否与营养状况和特应性皮炎的严重程度有关?
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-11-26 DOI: 10.1016/j.nut.2025.113023
Thalita Cremonesi Pereira Bachelli Ph.D. , Elisa Nunes Secamilli Ph.D. , Marina Gagheggi Maciel B.Sc. , Andrea Fernandes Eloy da Costa França Ph.D. , Cinthia Baú Betim Cazarin Ph.D.
Atopic dermatitis (AD) is a chronic and relapsing skin disease frequently observed in childhood with a multifactorial pathogenesis; however, diet is a contributing factor. Some studies have verified that fruit, vegetables, milk, or meat intake (>1x/wk) reduced the incidence of AD symptoms. Otherwise, highly frequent fast-food consumption (>1x/wk) is associated with increased AD symptoms. Also, elimination diets are common in individuals with AD and often conducted incorrectly. The present study hypothesizes that food intake can be associated with AD severity and nutritional status. A food frequency questionnaire was administered to assess food frequency and elimination diets, in addition to obtaining anthropometric data to estimate nutritional status. One hundred and four individuals participated in the study, with age ranging from 1 to 17 y and 11 mo. The results indicated no significant association between food intake and nutritional status or SCORAD (P > 0.05). Approximately 30% of participants reported elimination diets, of which 31% had no prescription. Elimination diet was adopted by 29.8% of participants, with most (67.7%) stating that they were restricting certain foods on the recommendation of a health care provider. Association between food intake and AD severity was not observed. However, the consumption of some ultra-processed foods was associated with nutritional status. We encourage qualitative research on food consumption and cause-effect research on the association between elimination diets and worsened AD symptoms. This study was registered at the Brazilian Registry of Clinical Trials—ReBEC (RBR-7q6g5b).
特应性皮炎(AD)是一种常见于儿童的慢性复发性皮肤病,具有多因素发病机制;然而,饮食是一个因素。一些研究已经证实,水果、蔬菜、牛奶或肉类的摄入量(每周1次)可以减少AD症状的发生。否则,频繁的快餐消费(每周1次)与阿尔茨海默病症状增加有关。此外,消除饮食在AD患者中很常见,但通常执行不当。本研究假设食物摄入可能与AD的严重程度和营养状况有关。除了获得人体测量数据以估计营养状况外,还进行了食物频率问卷调查以评估食物频率和消除饮食。共有104人参加了这项研究,年龄从1岁到17岁,11个月不等。结果表明,食物摄入量与营养状况或SCORAD之间没有显著关联(P > 0.05)。大约30%的参与者报告了消除饮食,其中31%没有处方。29.8%的参与者采用消除饮食,其中大多数(67.7%)表示他们根据医疗保健提供者的建议限制某些食物。没有观察到食物摄入与AD严重程度之间的联系。然而,一些超加工食品的消费与营养状况有关。我们鼓励对食物消费进行定性研究,并对消除饮食与阿尔茨海默病症状恶化之间的关系进行因果研究。该研究已在巴西临床试验注册中心rebec注册(RBR-7q6g5b)。
{"title":"Can food choices be associated with nutritional status and atopic dermatitis severity in children and adolescents?","authors":"Thalita Cremonesi Pereira Bachelli Ph.D. ,&nbsp;Elisa Nunes Secamilli Ph.D. ,&nbsp;Marina Gagheggi Maciel B.Sc. ,&nbsp;Andrea Fernandes Eloy da Costa França Ph.D. ,&nbsp;Cinthia Baú Betim Cazarin Ph.D.","doi":"10.1016/j.nut.2025.113023","DOIUrl":"10.1016/j.nut.2025.113023","url":null,"abstract":"<div><div>Atopic dermatitis (AD) is a chronic and relapsing skin disease frequently observed in childhood with a multifactorial pathogenesis; however, diet is a contributing factor. Some studies have verified that fruit, vegetables, milk, or meat intake (&gt;1x/wk) reduced the incidence of AD symptoms. Otherwise, highly frequent fast-food consumption (&gt;1x/wk) is associated with increased AD symptoms. Also, elimination diets are common in individuals with AD and often conducted incorrectly. The present study hypothesizes that food intake can be associated with AD severity and nutritional status. A food frequency questionnaire was administered to assess food frequency and elimination diets, in addition to obtaining anthropometric data to estimate nutritional status. One hundred and four individuals participated in the study, with age ranging from 1 to 17 y and 11 mo. The results indicated no significant association between food intake and nutritional status or SCORAD (<em>P &gt; 0.05</em>). Approximately 30% of participants reported elimination diets, of which 31% had no prescription. Elimination diet was adopted by 29.8% of participants, with most (67.7%) stating that they were restricting certain foods on the recommendation of a health care provider. Association between food intake and AD severity was not observed. However, the consumption of some ultra-processed foods was associated with nutritional status. We encourage qualitative research on food consumption and cause-effect research on the association between elimination diets and worsened AD symptoms. This study was registered at the Brazilian Registry of Clinical Trials—ReBEC (RBR-7q6g5b).</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113023"},"PeriodicalIF":3.0,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can regional phase angle reflect changes in physical fitness and body composition from late childhood to adolescence? A cohort study 区域相位角能否反映儿童期晚期到青春期身体素质和身体成分的变化?队列研究
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-11-23 DOI: 10.1016/j.nut.2025.113035
Núbia Maria Oliveira M.Sc. , Raquel Revuelta Iniesta Ph.D. , Dimitris Vlachopoulos Ph.D. , Alan R. Barker Ph.D. , Catarina Nunes Matias Ph.D. , Ezequiel Moreira Gonçalves Ph.D. , Eero A. Haapala Ph.D. , Timo A. Lakka Ph.D.

Objectives

It is unclear whether regional phase angle (R-PhA), measured by bioelectrical impedance (BIA), is associated with changes in physical fitness and body composition during growth. We examined longitudinal associations between R-PhA and these outcomes.

Methods

Two hundred seventy participants (122 girls) from the Physical Activity and Nutrition in Children (PANIC) study were analyzed at ages 9.7 ± 0.4 (T1) and 15.8 ± 0.4 years (T2). Multifrequency BIA provided R-PhA (arm, leg). Dual-energy X-ray absorptiometry (DXA) determined total lean mass (LM) and fat mass percentage (%FM). Handgrip strength (HS) and standing long jump (SLJ) were scaled by body mass. Peak oxygen uptake (VO₂peak) was measured using a cycle ergometer test and scaled by LM. Changes were calculated as T2–T1 (Δ). Regression models tested associations between Δ R-PhA and Δ outcomes (adjusted for pubertal status) and whether Δ R-PhA predicted T2 outcomes (adjusted for outcome, body composition, pubertal status, and moderate-to-vigorous physical activity at T1).

Results

ΔPhA-Arm was associated with ΔHS (β = 0.23 girls; β = 0.24 boys), ΔSLJ (β = 0.29; β = 0.38), ΔLM (β = 0.33; β = 0.45), and Δ%FM (β = −0.22 boys). ΔPhA-Leg was associated with ΔHS (β = 0.29 boys), ΔSLJ (β = 0.23; β = 0.25), ΔVO₂peak (β = 0.25 girls), ΔLM (β = 0.26; β = 0.59), and Δ%FM (β = 0.20; β = −0.24). At T2, ΔR-PhA positively predicted HS and SLJ in both sexes, LM in boys, and ΔPhA-Arm predicted LM in girls.

Conclusions

Increases in R-PhA were mainly related to gains in strength, power, and LM, indicating that PhA captures aspects of muscle function and composition. Nonetheless, its use for diagnostic or decision-making purposes remains to be clarified.
目前尚不清楚由生物电阻抗(BIA)测量的区域相位角(R-PhA)是否与生长过程中身体健康和身体成分的变化有关。我们研究了R-PhA与这些结果之间的纵向关联。方法分析来自儿童身体活动与营养(PANIC)研究的270名参与者(122名女孩),年龄为9.7±0.4 (T1)和15.8±0.4 (T2)岁。多频BIA提供R-PhA(臂、腿)。双能x射线吸收仪(DXA)测定总瘦质量(LM)和脂肪质量百分比(%FM)。握力(HS)和立定跳远(SLJ)以体重衡量。峰值摄氧量(vo2峰值)采用循环测功仪测试和LM缩放。计算变化为T2-T1 (Δ)。回归模型检验了Δ R-PhA与Δ结果(经青春期状态调整)之间的关系,以及Δ R-PhA是否预测T2结果(经T1时的结果、身体成分、青春期状态和中高强度体育活动调整)。ResultsΔPhA-Arm与ΔHS(女生β = 0.23,男生β = 0.24)、ΔSLJ(女生β = 0.29,男生β = 0.38)、ΔLM(女生β = 0.33,男生β = 0.45)和Δ%FM(男生β = - 0.22)相关。ΔPhA-Leg与ΔHS(β= 0.29男孩),ΔSLJ(β= 0.23,β= 0.25),ΔVO₂女孩(β= 0.25),峰值ΔLM(β= 0.26,β= 0.59),和Δ%调频(β= 0.20,β=−0.24)。T2时,ΔR-PhA正预测男女HS和SLJ,男生为LM,女生为ΔPhA-Arm正预测LM。结论R-PhA的增加主要与力量,力量和LM的增加有关,表明PhA捕获了肌肉功能和组成的各个方面。尽管如此,其用于诊断或决策目的仍有待澄清。
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引用次数: 0
Severe copper deficiency–related polyneuropathy following laparoscopic sleeve gastrectomy: A case report and literature review 腹腔镜袖式胃切除术后严重缺铜相关性多神经病变1例报告及文献复习
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-11-23 DOI: 10.1016/j.nut.2025.113036
Yu-Hao Huang M.D. , Mei-Chuan Chou M.D., M.Sc. , Jih-Jin Tsai M.D., Ph.D.

Background

Sleeve gastrectomy (SG) has become the most commonly performed bariatric procedure due to its favorable weight-loss outcomes and lower complication risks. However, serious neurological complications can still occur. We present a case of severe copper deficiency–related polyneuropathy following SG in a 48-y-old man.

Case Presentation

A 48-y-old man underwent laparoscopic SG for morbid obesity. Three months postoperatively, he developed poor oral intake. At 7 mo, he presented with bilateral distal paresthesia and gait disturbance. Symptoms transiently improved after vitamin B supplementation but progressively worsened. At 9 mo, he was admitted with severe polyneuropathy. Laboratory testing revealed marked hypocupremia. Intravenous copper supplementation led to substantial neurological improvement, and he was eventually discharged with neurological improvement.

Literature Review

Four reports involving five cases of polyneuropathy due to copper deficiency after SG or Roux-en-Y gastric bypass were identified in a search of the literature. Additionally, incidence rates of neurological complications and copper deficiency following SG and Roux-en-Y gastric bypass were reviewed.

Conclusions

In this case report, we emphasize vigilance regarding the presence of copper deficiency after SG, demonstrate that timely supplementation improves outcomes, recommend laboratory evaluation when postoperative neurological symptoms occur, and highlight the need for standardized postoperative copper monitoring and dosing guidelines.
背景袖式胃切除术(SG)由于其良好的减肥效果和较低的并发症风险,已成为最常用的减肥手术。然而,严重的神经系统并发症仍然可能发生。我们提出一个病例严重的铜缺乏相关的多发性神经病变后,SG在一个48岁的男子。病例介绍1例48岁男性,因病态肥胖行腹腔镜SG手术。术后3个月,患者出现口服不良。7个月时,患儿出现双侧远端感觉异常和步态障碍。补充维生素B后症状短暂改善,但逐渐恶化。9个月时,他被诊断为严重的多发性神经病。实验室检测显示明显的低铜血症。静脉补充铜导致了神经系统的显著改善,最终他出院时神经系统有所改善。文献综述:在文献检索中,我们发现了4例报告,涉及5例SG或Roux-en-Y胃旁路术后铜缺乏引起的多神经病变。此外,还回顾了SG和Roux-en-Y胃旁路术后神经系统并发症和铜缺乏的发生率。结论在本病例报告中,我们强调了对SG术后铜缺乏的警惕,证明了及时补充铜可以改善预后,建议在术后出现神经症状时进行实验室评估,并强调了标准化术后铜监测和给药指南的必要性。
{"title":"Severe copper deficiency–related polyneuropathy following laparoscopic sleeve gastrectomy: A case report and literature review","authors":"Yu-Hao Huang M.D. ,&nbsp;Mei-Chuan Chou M.D., M.Sc. ,&nbsp;Jih-Jin Tsai M.D., Ph.D.","doi":"10.1016/j.nut.2025.113036","DOIUrl":"10.1016/j.nut.2025.113036","url":null,"abstract":"<div><h3>Background</h3><div>Sleeve gastrectomy (SG) has become the most commonly performed bariatric procedure due to its favorable weight-loss outcomes and lower complication risks. However, serious neurological complications can still occur. We present a case of severe copper deficiency–related polyneuropathy following SG in a 48-y-old man.</div></div><div><h3>Case Presentation</h3><div>A 48-y-old man underwent laparoscopic SG for morbid obesity. Three months postoperatively, he developed poor oral intake. At 7 mo, he presented with bilateral distal paresthesia and gait disturbance. Symptoms transiently improved after vitamin B supplementation but progressively worsened. At 9 mo, he was admitted with severe polyneuropathy. Laboratory testing revealed marked hypocupremia. Intravenous copper supplementation led to substantial neurological improvement, and he was eventually discharged with neurological improvement.</div></div><div><h3>Literature Review</h3><div>Four reports involving five cases of polyneuropathy due to copper deficiency after SG or Roux-en-Y gastric bypass were identified in a search of the literature. Additionally, incidence rates of neurological complications and copper deficiency following SG and Roux-en-Y gastric bypass were reviewed.</div></div><div><h3>Conclusions</h3><div>In this case report, we emphasize vigilance regarding the presence of copper deficiency after SG, demonstrate that timely supplementation improves outcomes, recommend laboratory evaluation when postoperative neurological symptoms occur, and highlight the need for standardized postoperative copper monitoring and dosing guidelines.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113036"},"PeriodicalIF":3.0,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sweet Foods Intake and Risk of Pancreatic Diseases: A large cohort study from the UK Biobank 甜食摄入与胰腺疾病风险:来自英国生物银行的一项大型队列研究
IF 3 3区 医学 Q2 NUTRITION & DIETETICS Pub Date : 2025-11-23 DOI: 10.1016/j.nut.2025.113032
Yuqi Liu , Hanke Ma , Yin Lu , Donglin Jiang , Ling Liu , Yongjian Zhu , Yacong Bo , Peng Wang , Jianxiang Shi , Lin Shang , Chensu Yang , Hua Ye , Qiaozhen Cai

Objectives

Growing evidence has linked sweet food intake to obesity, diabetes, and mortality, but its association with pancreatic disease remains underexplored.

Methods

A total of 136 367 participants aged 40–69 y from the UK Biobank were included. Sweet food intake was assessed through dietary questionnaires, and pancreatic disease outcomes were identified using clinical and self-reported data. Multivariable Cox proportional hazards regression models were employed to estimate the hazard ratios (HRs) for pancreatic disease risk across quartiles of sweet food intake.

Results

During a median (interquartile range) follow-up of 11.6 (11.2–12.4) y, 348 pancreatic cancer events, 527 acute pancreatitis events, and 319 chronic pancreatitis events occurred. Higher sweet food intake was associated with an increased risk of chronic pancreatitis (HRQuartile 4 vs. Quartile 1: 1.87; 95% confidence interval [CI], 1.32–2.64; Ptrend < 0.001) but not with pancreatic cancer (HRQuartile 4 vs. Quartile 1: 1.11; 95% CI, 0.80–1.53; Ptrend = 0.60) or acute pancreatitis (HRQuartile 4 vs. Quartile 1: 0.95; 95% CI, 0.72–1.23; Ptrend = 0.65).

Conclusions

Findings from this cohort study suggest that lower intake of sweet foods may reduce the risk of chronic pancreatitis.
越来越多的证据表明,甜食摄入与肥胖、糖尿病和死亡率有关,但其与胰腺疾病的关系仍未得到充分探讨。方法从英国生物银行(UK Biobank)中选取年龄在40-69岁的133667名受试者。通过饮食问卷评估甜食摄入量,并通过临床和自我报告数据确定胰腺疾病的结局。采用多变量Cox比例风险回归模型来估计不同甜食摄入四分位数胰腺疾病风险的风险比(hr)。结果在中位(四分位数范围)随访11.6(11.2-12.4)年期间,发生了348例胰腺癌事件,527例急性胰腺炎事件和319例慢性胰腺炎事件。较高的甜食摄入量与慢性胰腺炎风险增加相关(hr4四分位数vs四分位数1:1.87;95%可信区间[CI], 1.32-2.64; Ptrend < 0.001),但与胰腺癌(hr4四分位数vs四分位数1:1.11;95% CI, 0.80-1.53; Ptrend = 0.60)或急性胰腺炎(hr4四分位数vs四分位数1:0.95;95% CI, 0.72-1.23; Ptrend = 0.65)无关。结论:这项队列研究的结果表明,减少甜食的摄入可能会降低慢性胰腺炎的风险。
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Nutrition
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