Oncology nursing forum最新文献

Objectives: To assess whether the use of patient-reported outcomes (PROs) is associated with patient empowerment (PE) in cancer survivors in early survivorship.

Sample & setting: A convenience sample of 83 adult cancer survivors participated in a quantitative repeated-measures study at a community-based cancer center, and 33 participants who received chemotherapy as the last treatment modality of their primary cancer treatment completed a questionnaire immediately following treatment and at three months.

Methods & variables: Participants were recruited from the medical oncology clinic by oncology nurse research assistants and completed an electronic or paper survey composed of three instruments.

Results: A significant relationship was found between PE and self-efficacy, and a significant negative correlation was observed between self-efficacy and symptoms. PRO self-efficacy predicted PE following chemotherapy treatment. PE decreased at three months post-treatment.

Implications for nursing: Clinician-driven assessment is less sustainable in survivorship care. The use of PROs for symptoms and self-efficacy is related to PE. A qualitative study for conceptual clarification of PE in cancer survivors is needed. Oncology nurses are key to envisioning how to implement survivor-reported symptom assessment that builds empowerment.

Problem identification: This systematic review was conducted to inform the development of clinical practice guidelines on the management of extravasation of antineoplastic agents in patients with cancer.

Literature search: PubMed®, Embase®, CINAHL®, and Cochrane databases were searched for eligible studies from June 2014 to June 2024. Citations of guidelines and a previous systematic review were reviewed for records that met eligibility criteria. Two reviewers independently screened titles, abstracts, and full texts for inclusion.

Data evaluation: Two independent reviewers assessed all studies that met inclusion criteria using the Risk of Bias in Nonrandomized Studies of Interventions for cohort studies and JBI critical appraisal tool for case series. The certainty of evidence was assessed using GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology.

Synthesis: For patients who have an extravasation of an antineoplastic agent, although there is very low certainty in the evidence overall, interventions include administration of an antidote, compress, and surgical referral or escalation of care for extravasation of central lines.

Implications for practice: Antidotes, application of a compress, and referral for surgical or wound care are effective strategies for managing extravasation of antineoplastic agents.

Objectives: To explore the relationship between intolerance of uncertainty (IU) and executive function (EF) in individuals with breast cancer.

Sample & setting: 21 postmenopausal women aged 45-75 years with stage I-III breast cancer who completed chemotherapy 3-12 months before enrollment were included.

Methods & variables: In this pilot cross-sectional study, participants completed a task to probe neural responses to unpredictable threats, and anterior insula activation indicated objective IU. EF was measured by a neuropsychological test. Other self-reported measures were used to assess anxiety and fatigue.

Results: Results indicated that individuals with high objective IU demonstrated lower EF. No main effect of subjective IU on EF was found, and no mediation effect of anxiety on the relationship between IU and EF was found.

Implications for nursing: Healthcare providers need to consider IU when planning and providing survivorship education. Further research is needed to enhance the understanding of the role of IU on EF problems among individuals with breast cancer.

Problem identification: Hematopoietic stem cell transplantation has significant psychosocial impacts on pediatric sibling donors, including emotional distress, guilt, and anxiety. The aim of this qualitative review is to explore their experiences and the challenges they face.

Literature search: A systematic review of qualitative studies of sibling donors was conducted using JBI guidelines. A search of MEDLINE®, Scopus®, CINAHL®, PsycINFO®, and ProQuest identified nine qualitative studies involving 70 sibling donors.

Data evaluation: Studies were critically appraised using JBI methodology for systematic reviews of qualitative evidence. Data were synthesized to understand psychosocial experiences of sibling donors.

Synthesis: The following four main themes emerged: (a) Sibling donors felt trapped and experienced mixed emotions about donating, (b) family life was significantly disrupted after the sibling's illness, (c) donors developed a sense of pride from being able to help their sibling, and (d) the donation process required better emotional support for the donors.

Implications for practice: Pediatric healthcare professionals should offer specialized psychosocial support to sibling donors. Additional qualitative research is needed to assess the long-term psychosocial effects on these donors.

DNP-prepared nurses bring clinical expertise, clinical system-level thinking, and a focus on implementation science. PhD-prepared nurses contribute knowledge of research design, methodology, and data analysis. Together, they.

Objectives: To assess the impact of Snyder's hope theory-guided nursing care combined with continuity of care on postoperative individuals with glioma undergoing chemotherapy.

Sample & setting: 112 patients with glioma receiving postoperative chemotherapy were randomly assigned to control and observation groups.

Methods & variables: The control group received routine nursing whereas the observation group received additional care based on Snyder's hope theory, combined with continuous nursing. Negative emotions, self-care agency, cancer-related fatigue, hope levels, quality of life, adverse reactions, and nursing satisfaction were compared between the groups.

Results: The observation group showed significantly lower anxiety and depression (p < 0.05) and higher self-care advocacy, hope levels, and quality of life than the control group (p < 0.05). Fatigue and the incidence of adverse reactions were significantly lower in the observation group (p < 0.05). Nursing satisfaction in the observation group was significantly higher.

Implications for nursing: Snyder's hope theory-guided nursing care with continuity of care improves psychological well-being, self-care agency, and quality of life, and reduces fatigue and side effects among individuals with glioma undergoing chemotherapy.

Purpose: To culturally adapt Helping Her Heal (HHH), a nurse-delivered educational counseling intervention for spouse caregivers of women with breast cancer, for applicability in Ghana, Africa.

Participants & setting: Four spouses of women with breast cancer and two nurses in breast clinics were interviewed to review HHH for adaptability.

Methodologic approach: The Ecological Validity Model guided the cultural adaptation of HHH to review the intervention, have Ghanaian nurses review the HHH manuals, modify the original HHH to the targeted demographic, verify the adaptation, and review for acceptability.

Findings: The intervention manuals needed minor modifications in three of the eight dimensions of the Ecological Validity Model: language, content, and metaphor. The structure and focus of each intervention session did not need changes.

Implications for nursing: Findings from this study have laid the groundwork for the cultural adaption of studies. This study is the first step in the process of adapting an intervention for spouse caregivers that will be used by breast cancer nurses in the delivery of care.

Objectives: To investigate the mediating effect of self-efficacy (SE) on the relationships among patient-provider partnership (PPP), pain, and quality of life (QOL) in individuals with cancer.

Sample & setting: Individuals with cancer were recruited online through cancer organizations and social media support groups in 2023.

Methods & variables: This cross-sectional survey collected data on demographic/clinical characteristics, cancer pain outcomes, PPP, SE for cancer pain management, and QOL. Mediation analyses assessed the role of SE in the relationships among PPP, pain, and QOL.

Results: Most participants were female, White, and aged 18-60 years. SE mediated the relationships between PPP and pain severity, pain interference, QOL function, and QOL symptoms. Greater PPP was associated with higher SE.

Implications for nursing: A supportive PPP is essential for improving pain outcomes and QOL in individuals with cancer by strengthening their SE.

Purpose: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN).

Participants & setting: Participants were older adults with AML (N = 17) receiving HMA + VEN at a comprehensive cancer center. Most were male and aged 64-89 years (median age = 75 years).

Methodologic approach: This study used a longitudinal qualitative approach with semistructured interviews at cycles 1, 2, and 7 of chemotherapy. Interviews were audio recorded, transcribed, coded, and analyzed using thematic analysis.

Findings: Four themes were identified: reduced mobility and limited options for physical activities (cycle 1), periodic changes in mobility and energy level (cycle 2), acceptance and adaptation to changed mobility (cycle 7), and strategies to stay active.

Implications for nursing: Substantial challenges with physical function and mobility exist for older adults undergoing treatment for AML. Oncology nurses should anticipate patient needs, provide appropriate care, and make referrals to address physical and functional needs before and during HMA + VEN treatment.

Objectives: To determine the relationship between chemotherapy-induced peripheral neuropathy (CIPN) severity and centrosomal protein 72 (CEP72) genotype in young adults receiving paclitaxel or vincristine.

Sample & setting: 50 young adults aged 21-39 years who were expected to receive a cumulative dose of at least 7 mg vincristine or 700 mg/m2 paclitaxel for the treatment of cancer were recruited from Dana-Farber Cancer Institute.

Methods & variables: Participants completed a CIPN assessment tool and provided a blood sample before the first infusion. Participants completed the assessment tool at two additional time points. DNA was genotyped for CEP72 rs924607. CIPN scores were compared between those with the TT versus the CC or CT genotype over time using linear mixed-effects models.

Results: Young adults receiving vincristine with the TT CEP72 genotype experienced higher CIPN severity by the final time point, but the differences were not statistically significant (p > 0.05).

Implications for nursing: Future work to validate biomarkers like CEP72 may allow clinicians to identify patients who may benefit from altered chemotherapy dosages relative to CIPN risk.