Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931348
L. Matušková, B. Czippelova, Z. Turianikova, D. Švec, Z. Kolková, Z. Lasabová, M. Javorka
$upbeta$-adrenergic receptors ($upbeta$-ARs) playa pivotal role in the cardiovascular control. Several single nucleotide polymorphisms (SNPs) of $upbeta$-ARs might influence cardiovascular function. We aimed to explore the associations between four selected $upbeta$-ARs gene polymorphisms and cardiovascular control related measures in young healthy subjects. We conclude that complex analysis of various cardiovascular characteristics reflecting the strength of cardiac contraction and blood pressure variability can reveal subtle differences in cardiovascular sympathetic nervous control associated with $upbeta$-ARs polymorphisms.
{"title":"Beta-adrenergic receptors gene polymorphisms effects on cardiovascular control","authors":"L. Matušková, B. Czippelova, Z. Turianikova, D. Švec, Z. Kolková, Z. Lasabová, M. Javorka","doi":"10.1109/ESGCO55423.2022.9931348","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931348","url":null,"abstract":"$upbeta$-adrenergic receptors ($upbeta$-ARs) playa pivotal role in the cardiovascular control. Several single nucleotide polymorphisms (SNPs) of $upbeta$-ARs might influence cardiovascular function. We aimed to explore the associations between four selected $upbeta$-ARs gene polymorphisms and cardiovascular control related measures in young healthy subjects. We conclude that complex analysis of various cardiovascular characteristics reflecting the strength of cardiac contraction and blood pressure variability can reveal subtle differences in cardiovascular sympathetic nervous control associated with $upbeta$-ARs polymorphisms.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114507091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931376
V. Bari, F. Gelpi, B. Cairo, Noemi Cornara, Beatrice De Maria, M. Ranucci, A. Porta
A squared coherence (K2) approach was applied to investigate cerebral autoregulation (CA) in 33 patients (age: 63±14 yrs; 27 males) undergoing surgical aortic valve replacement (SAVR) before surgery (PRE), after surgery (POST) and after a 3-month follow-up (POST3). K2 was assessed between mean arterial pressure and mean cerebral blood flow velocity in very low frequency (VLF, 0.02-0.07 Hz), low frequency (LF, 0.07-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) bands at rest in supine position (REST) and during active standing (STAND). The significance of K2 was tested individually via a surrogate approach. Results showed that K2 in HF band increased during POST compared to PRE at REST but this rise was more limited during STAND. Analysis of K2 suggests a possible impairment of CA after SAVR that might expose patients to a higher risk of developing post-surgery cerebrovascular adverse events.
{"title":"Squared Coherence Analysis Might Suggest Cerebral Autoregulation Post-Surgery Impairment in Patients Undergoing Surgical Aortic Valve Replacement","authors":"V. Bari, F. Gelpi, B. Cairo, Noemi Cornara, Beatrice De Maria, M. Ranucci, A. Porta","doi":"10.1109/ESGCO55423.2022.9931376","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931376","url":null,"abstract":"A squared coherence (K2) approach was applied to investigate cerebral autoregulation (CA) in 33 patients (age: 63±14 yrs; 27 males) undergoing surgical aortic valve replacement (SAVR) before surgery (PRE), after surgery (POST) and after a 3-month follow-up (POST3). K2 was assessed between mean arterial pressure and mean cerebral blood flow velocity in very low frequency (VLF, 0.02-0.07 Hz), low frequency (LF, 0.07-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) bands at rest in supine position (REST) and during active standing (STAND). The significance of K2 was tested individually via a surrogate approach. Results showed that K2 in HF band increased during POST compared to PRE at REST but this rise was more limited during STAND. Analysis of K2 suggests a possible impairment of CA after SAVR that might expose patients to a higher risk of developing post-surgery cerebrovascular adverse events.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126253558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931344
Congcong Huo, Simin Zhang, Gongcheng Xu, Zengyong Li
Observation of the cortical response to specific therapy in real-time would provide valuable evidence for the neural mechanisms underlying stroke rehabilitation. This study aimed to explore the cortical response during acupuncture in hemiplegic limb acupoints for stroke patients. Nineteen stroke patients were recruited for the measurement of cerebral hemodynamics during resting state and acupuncture state based on functional near-infrared spectroscopy (fNIRS). Wavelet amplitude (WA) was used to describe the cortical activation based on the time-frequency analysis of fNIRS signals. Results showed significantly higher WA of bilateral prefrontal and motor cortex during acupuncture state than the resting state. Additionally, significantly negative correlation was observed between the motor score and increased WA in the contralesional hemisphere. These findings suggest that there were increased cortical activation of bilateral hemispheres and patients with severe motor dysfunctions had more activation of contralesional hemisphere in response to the acupuncture intervention. This study provides preliminary evidence about the neural mechanism underlying acupuncture for motor impairment and suggests the role of fNIRS in stroke rehabilitation assessment.
{"title":"Cortical Activation Response during Acupuncture Intervention for Hemiplegia Limbs in Stroke Patients: A Preliminary fNIRS Study","authors":"Congcong Huo, Simin Zhang, Gongcheng Xu, Zengyong Li","doi":"10.1109/ESGCO55423.2022.9931344","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931344","url":null,"abstract":"Observation of the cortical response to specific therapy in real-time would provide valuable evidence for the neural mechanisms underlying stroke rehabilitation. This study aimed to explore the cortical response during acupuncture in hemiplegic limb acupoints for stroke patients. Nineteen stroke patients were recruited for the measurement of cerebral hemodynamics during resting state and acupuncture state based on functional near-infrared spectroscopy (fNIRS). Wavelet amplitude (WA) was used to describe the cortical activation based on the time-frequency analysis of fNIRS signals. Results showed significantly higher WA of bilateral prefrontal and motor cortex during acupuncture state than the resting state. Additionally, significantly negative correlation was observed between the motor score and increased WA in the contralesional hemisphere. These findings suggest that there were increased cortical activation of bilateral hemispheres and patients with severe motor dysfunctions had more activation of contralesional hemisphere in response to the acupuncture intervention. This study provides preliminary evidence about the neural mechanism underlying acupuncture for motor impairment and suggests the role of fNIRS in stroke rehabilitation assessment.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128360754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931377
F. Gelpi, V. Bari, B. Cairo, Beatrice De Maria, R. Wells, M. Baumert, A. Porta
Information transferred from heart period (HP) to systolic arterial pressure (SAP) along baroreflex and from mean arterial pressure (MAP) to mean cerebral blood flow (MCBF) along the pressure-to-flow relationship is commonly estimated by conditioning for the respiratory activity. Results might depend on the type of selected respiratory signal. In 18 healthy individuals (age: 28±13 yrs; 5 males) we acquired the spontaneous variability of HP, SAP, MAP and MCBF and two respiratory signals, namely respiratory chest movement (RCM) and end-tidal carbon dioxide (EtCO2). Data were acquired at rest in supine position (REST) and during active standing (STAND). The effect of STAND over the information transfer from MAP to MCBF was similar using RCM or EtCO2, while it was different when information transfer from SAP to HP was evaluated. Changes of the information transfer during STAND suggests that EtCO2 is a weak conditioning signal for the evaluation of information transferred along baroreflex.
{"title":"Cardiovascular and Cerebrovascular Information Transfer Might Depend on the Type of Conditioning Respiratory Signal","authors":"F. Gelpi, V. Bari, B. Cairo, Beatrice De Maria, R. Wells, M. Baumert, A. Porta","doi":"10.1109/ESGCO55423.2022.9931377","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931377","url":null,"abstract":"Information transferred from heart period (HP) to systolic arterial pressure (SAP) along baroreflex and from mean arterial pressure (MAP) to mean cerebral blood flow (MCBF) along the pressure-to-flow relationship is commonly estimated by conditioning for the respiratory activity. Results might depend on the type of selected respiratory signal. In 18 healthy individuals (age: 28±13 yrs; 5 males) we acquired the spontaneous variability of HP, SAP, MAP and MCBF and two respiratory signals, namely respiratory chest movement (RCM) and end-tidal carbon dioxide (EtCO2). Data were acquired at rest in supine position (REST) and during active standing (STAND). The effect of STAND over the information transfer from MAP to MCBF was similar using RCM or EtCO2, while it was different when information transfer from SAP to HP was evaluated. Changes of the information transfer during STAND suggests that EtCO2 is a weak conditioning signal for the evaluation of information transferred along baroreflex.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"2019 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134343002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931379
Juliane Bjerkan, Sultan Alatawi, Nora Ugland, M. Elstad, A. Stefanovska
Here we adopt the definition of respiratory sinus arrhythmia (RSA) as the heart rate variability (HRV) in synchrony with respiration amplitude. Little is known about the effect ambient temperature has on RSA, and as RSA has potential as a biomarker for various conditions its effect should be examined. Here, employing wavelet analysis, we investigate HRV synchrony with both respiration amplitude and respiration frequency in 27 healthy adults at three ambient temperatures (20°C. 26°C. 32°C). Clinical Relevance- This work establishes that in healthy adults the amount of synchrony between HRV and respiration amplitude and between HRV and respiration frequency remains constant for temperatures between 20°C and 32°C
{"title":"Cardio-respiratory wavelet phase coherence at three ambient temperatures","authors":"Juliane Bjerkan, Sultan Alatawi, Nora Ugland, M. Elstad, A. Stefanovska","doi":"10.1109/ESGCO55423.2022.9931379","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931379","url":null,"abstract":"Here we adopt the definition of respiratory sinus arrhythmia (RSA) as the heart rate variability (HRV) in synchrony with respiration amplitude. Little is known about the effect ambient temperature has on RSA, and as RSA has potential as a biomarker for various conditions its effect should be examined. Here, employing wavelet analysis, we investigate HRV synchrony with both respiration amplitude and respiration frequency in 27 healthy adults at three ambient temperatures (20°C. 26°C. 32°C). Clinical Relevance- This work establishes that in healthy adults the amount of synchrony between HRV and respiration amplitude and between HRV and respiration frequency remains constant for temperatures between 20°C and 32°C","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133219691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931360
Chiara Barà, R. Pernice, Laura Sparacino, S. Mangione, M. Javorka, L. Faes
Although Heart Period (HP) variability is the most widely used measure to assess cardiovascular oscillations, its evaluation combined with that of Pulse Arrival Time (PAT) variability may provide additional information about cardiac dynamics and cardiovascular interactions. In this study, we computed the transfer entropy from PAT to HP in 76 subjects monitored at rest and during orthostatic and mental stress using both a model-free (k-Nearest Neighbors) and a linear parametric estimator. Our results show how the information flow between these two variables depends on the physiological condition and how the nonlinear measure captures more information than the linear one during orthostatic stress.
{"title":"Transfer Entropy Analysis of Pulse Arrival Time - Heart Period Interactions during Physiological Stress","authors":"Chiara Barà, R. Pernice, Laura Sparacino, S. Mangione, M. Javorka, L. Faes","doi":"10.1109/ESGCO55423.2022.9931360","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931360","url":null,"abstract":"Although Heart Period (HP) variability is the most widely used measure to assess cardiovascular oscillations, its evaluation combined with that of Pulse Arrival Time (PAT) variability may provide additional information about cardiac dynamics and cardiovascular interactions. In this study, we computed the transfer entropy from PAT to HP in 76 subjects monitored at rest and during orthostatic and mental stress using both a model-free (k-Nearest Neighbors) and a linear parametric estimator. Our results show how the information flow between these two variables depends on the physiological condition and how the nonlinear measure captures more information than the linear one during orthostatic stress.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127988423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931386
Julia Erhardt, J. Brock, Stephan A Eisler, M. Hörning
The integrity and functionality of all living tissue highly depends on their embedding in the extracellular matrix (ECM). It provides cells with a certain rigidity and various types of proteins to ensure stability, nutrition and anchorage of the single cells and tissue. These properties highly impact all tissue types, including the here discussed heart tissue. In cardiac muscle, tissue stiffness plays an especially critical role, since it can impair regular functions by disturbing natural electrophysiological conduction. An often discussed but not entirely understood subject is alternans. It is commonly ac-cepted that alternans can pathologically disturb natural cardiac rhythms and thereby lead to life-threatening medical conditions. Previous studies have gained insights on the influence of cardiac tissue stiffness on electrophysiological dynamics, but details about their formation remain to be elucidated. Here, we address the effects of variations in the ECM rigidity and matrix protein composition on the cardiac tissue morphology and dynamic alternans patterns. Employing a combination of high-speed life imaging, classical fluorescence staining and machine learning algorithms, we elucidate the critical relationship between tissue morphology and electromechanical dynamics. Clinical Relevance-Using high-speed life imaging, this work aims at understanding the connection between tissue morphology, ECM composition and alternans dynamics in healthy and diseased heart tissues for possible future applications, treatments and prediction of cardiac diseases.
{"title":"Extracellular matrix composition controls the development of alternans in cardiac tissue","authors":"Julia Erhardt, J. Brock, Stephan A Eisler, M. Hörning","doi":"10.1109/ESGCO55423.2022.9931386","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931386","url":null,"abstract":"The integrity and functionality of all living tissue highly depends on their embedding in the extracellular matrix (ECM). It provides cells with a certain rigidity and various types of proteins to ensure stability, nutrition and anchorage of the single cells and tissue. These properties highly impact all tissue types, including the here discussed heart tissue. In cardiac muscle, tissue stiffness plays an especially critical role, since it can impair regular functions by disturbing natural electrophysiological conduction. An often discussed but not entirely understood subject is alternans. It is commonly ac-cepted that alternans can pathologically disturb natural cardiac rhythms and thereby lead to life-threatening medical conditions. Previous studies have gained insights on the influence of cardiac tissue stiffness on electrophysiological dynamics, but details about their formation remain to be elucidated. Here, we address the effects of variations in the ECM rigidity and matrix protein composition on the cardiac tissue morphology and dynamic alternans patterns. Employing a combination of high-speed life imaging, classical fluorescence staining and machine learning algorithms, we elucidate the critical relationship between tissue morphology and electromechanical dynamics. Clinical Relevance-Using high-speed life imaging, this work aims at understanding the connection between tissue morphology, ECM composition and alternans dynamics in healthy and diseased heart tissues for possible future applications, treatments and prediction of cardiac diseases.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129152790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931345
M. Andrzejewska, Mateusz Ozimek, Karolina Rams, T. Buchner
A system which responds strongly to stimuli is more asymmetric in time. We show this effect in RR intervals and also in amplitudes of QRS and T complex of the ECG in the groups of 67 long QT syndrome (LQTS) patients and 128 healthy controls from THEW database. We claim that it reflects a diminished response to inotropic and chronotropic control of cardiac effector in this pathology. Measured based on difference of amplitudes between consecutive beats are the best, especially the D index (Hou et al.), which utilizes poor overlap between paired variables. Clinical Relevance-Clinical indices of asymmetry differen-tiate between LQTS and healthy individuals and may be used to stratify risk in LQTS and other patients threatened by arrhythmia
{"title":"Asymmetry of RR intervals and ECG amplitudes in LQTS patients","authors":"M. Andrzejewska, Mateusz Ozimek, Karolina Rams, T. Buchner","doi":"10.1109/ESGCO55423.2022.9931345","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931345","url":null,"abstract":"A system which responds strongly to stimuli is more asymmetric in time. We show this effect in RR intervals and also in amplitudes of QRS and T complex of the ECG in the groups of 67 long QT syndrome (LQTS) patients and 128 healthy controls from THEW database. We claim that it reflects a diminished response to inotropic and chronotropic control of cardiac effector in this pathology. Measured based on difference of amplitudes between consecutive beats are the best, especially the D index (Hou et al.), which utilizes poor overlap between paired variables. Clinical Relevance-Clinical indices of asymmetry differen-tiate between LQTS and healthy individuals and may be used to stratify risk in LQTS and other patients threatened by arrhythmia","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126330350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931351
M. Alkhodari, N. Widatalla, Maisam Wahbah, Raghad Al Sakaii, Kiyoe Funamoto, A. Krishnan, Y. Kimura, Ahsan H. Khandoker
This study aims to investigate the associations of maternal-fetal demographic information (age, gestational age, and body mass index (BMI)) and heart rate variability with their cardiac coupling mechanisms during pregnancy. Coupling was determined from one-minute maternal-fetal electrocardio-graphy (ECG) signals in 172 pregnant women using phase coherence (λ) calculations. Accordingly, variables such as gestational age, maternal BMI, and maternal-fetal heart rate were found significant (p-value < 0.05) in discriminating between [1:2], [2:3], and [3:5] coupling scenarios. The results suggest the importance of maternal-fetal parameters and ECG recordings in the assessment of fetal well-being during pregnancy. Clinical Relevance-The maternal psychophysiological states are highly correlated with the fetal cardiac system. Accurate characterization of this correlation leads to better clinical assessment protocols and treatment plans to prevent many stillbirth cases
{"title":"Association between maternal-fetal cardiac coupling strengths with maternal and fetal parameters","authors":"M. Alkhodari, N. Widatalla, Maisam Wahbah, Raghad Al Sakaii, Kiyoe Funamoto, A. Krishnan, Y. Kimura, Ahsan H. Khandoker","doi":"10.1109/ESGCO55423.2022.9931351","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931351","url":null,"abstract":"This study aims to investigate the associations of maternal-fetal demographic information (age, gestational age, and body mass index (BMI)) and heart rate variability with their cardiac coupling mechanisms during pregnancy. Coupling was determined from one-minute maternal-fetal electrocardio-graphy (ECG) signals in 172 pregnant women using phase coherence (λ) calculations. Accordingly, variables such as gestational age, maternal BMI, and maternal-fetal heart rate were found significant (p-value < 0.05) in discriminating between [1:2], [2:3], and [3:5] coupling scenarios. The results suggest the importance of maternal-fetal parameters and ECG recordings in the assessment of fetal well-being during pregnancy. Clinical Relevance-The maternal psychophysiological states are highly correlated with the fetal cardiac system. Accurate characterization of this correlation leads to better clinical assessment protocols and treatment plans to prevent many stillbirth cases","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125297512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-09DOI: 10.1109/ESGCO55423.2022.9931354
P. Castiglioni, G. Merati, G. Parati, A. Faini
Distribution Entropy (DistEn) has been proposed to quantify the heart rate variability (HRV) complexity as an alternative to Sample (SampEn) or Fuzzy (FuzzyEn) entropies, which essentially measure the HRV randomness. We aim to evaluate if postural sympathovagal activations in healthy individuals induce changes in HRV complexity or randomness by jointly estimating DistEn, SampEn, and FuzzyEn. We compared the estimators on white, pink, and random noises, and on chaotic and periodic series. Then, we considered supine (Sup) and sitting (Sit) heart-rate recordings of 34 volunteers comparing SampEn, FuzzyEn, and DistEn between postures. Synthesized series highlighted the different nature of the estimators, being the highest entropy that of white noise for SampEn and FuzzyEn, that of the chaotic series for DistEn. SampEn and FuzzyEn of real heart rate series were greater in Sup, while DistEn did not differ between postures. Thus, the postural change does not change the HRV complexity as quantified by DistEn and DistEn is not an index of sympathovagal balance, unlike SampEn or FuzzyEn.
{"title":"Complexity in Heart Rate Variability after Postural Sympathovagal Change by Sample, Fuzzy, and Distribution Entropy","authors":"P. Castiglioni, G. Merati, G. Parati, A. Faini","doi":"10.1109/ESGCO55423.2022.9931354","DOIUrl":"https://doi.org/10.1109/ESGCO55423.2022.9931354","url":null,"abstract":"Distribution Entropy (DistEn) has been proposed to quantify the heart rate variability (HRV) complexity as an alternative to Sample (SampEn) or Fuzzy (FuzzyEn) entropies, which essentially measure the HRV randomness. We aim to evaluate if postural sympathovagal activations in healthy individuals induce changes in HRV complexity or randomness by jointly estimating DistEn, SampEn, and FuzzyEn. We compared the estimators on white, pink, and random noises, and on chaotic and periodic series. Then, we considered supine (Sup) and sitting (Sit) heart-rate recordings of 34 volunteers comparing SampEn, FuzzyEn, and DistEn between postures. Synthesized series highlighted the different nature of the estimators, being the highest entropy that of white noise for SampEn and FuzzyEn, that of the chaotic series for DistEn. SampEn and FuzzyEn of real heart rate series were greater in Sup, while DistEn did not differ between postures. Thus, the postural change does not change the HRV complexity as quantified by DistEn and DistEn is not an index of sympathovagal balance, unlike SampEn or FuzzyEn.","PeriodicalId":199691,"journal":{"name":"2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116779950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：