{"title":"Chimeric Antigen Receptor T-Cell Treatment in Children.","authors":"Zoe King, Ellen Fraint","doi":"10.1542/pir.2023-006126","DOIUrl":"10.1542/pir.2023-006126","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Altered Mental Status and Hypertension in an 8-year-old Boy.","authors":"Alexandra A Himes, Anjali Kirpalani","doi":"10.1542/pir.2022-005656","DOIUrl":"10.1542/pir.2022-005656","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raysa Morales-Demori, Ryan Coleman, George B Mallory
{"title":"Pediatric Pulmonary Hypertension.","authors":"Raysa Morales-Demori, Ryan Coleman, George B Mallory","doi":"10.1542/pir.2023-006010","DOIUrl":"10.1542/pir.2023-006010","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ecchymotic Skin Lesions and Hand Edema in a 10-month-old Boy.","authors":"Caitlyn Glover, Alexander K C Leung, Joseph M Lam","doi":"10.1542/pir.2023-006114","DOIUrl":"10.1542/pir.2023-006114","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Macartney Welborn, Samantha A Cresoe, Kiran Motaparthi, Jennifer L Thompson
{"title":"Persistent Lip Swelling in a Teenage Girl.","authors":"Macartney Welborn, Samantha A Cresoe, Kiran Motaparthi, Jennifer L Thompson","doi":"10.1542/pir.2022-005710","DOIUrl":"10.1542/pir.2022-005710","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal Alcohol Spectrum Disorders.","authors":"Elaine Maria Pereira","doi":"10.1542/pir.2023-006038","DOIUrl":"10.1542/pir.2023-006038","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanie C Marsh, Guillermo Yepes Junquera, Emily Stonebrook, John David Spencer, Joshua R Watson
Despite the American Academy of Pediatrics guidelines for the evaluation, treatment, and management of urinary tract infections (UTIs), UTI diagnosis and management remains challenging for clinicians. Challenges with acute UTI management stem from vague presenting signs and symptoms, diagnostic uncertainty, limitations in laboratory testing, and selecting appropriate antibiotic therapy in an era with increasing rates of antibiotic-resistant uropathogens. Recurrent UTI management remains difficult due to an incomplete understanding of the factors contributing to UTI, when to assess a child with repeated infections for kidney and urinary tract anomalies, and limited prevention strategies. To help reduce these uncertainties, this review provides a comprehensive overview of UTI epidemiology, risk factors, diagnosis, treatment, and prevention strategies that may help pediatricians overcome the challenges associated with acute and recurrent UTI management.
尽管美国儿科学会（American Academy of Pediatrics）制定了尿路感染（UTI）的评估、治疗和管理指南，但UTI 的诊断和管理对临床医生来说仍然具有挑战性。急性尿路感染管理面临的挑战来自于模糊的症状和体征、诊断的不确定性、实验室检测的局限性，以及在抗生素耐药尿路病原体日益增多的时代选择适当的抗生素治疗。由于对导致尿毒症的因素了解不全面，何时对反复感染的儿童进行肾脏和尿路异常评估，以及预防策略有限，因此复发性尿毒症的治疗仍然困难重重。为了帮助减少这些不确定性，本综述全面概述了 UTI 的流行病学、风险因素、诊断、治疗和预防策略，可帮助儿科医生克服急性和复发性 UTI 管理方面的挑战。
{"title":"Urinary Tract Infections in Children.","authors":"Melanie C Marsh, Guillermo Yepes Junquera, Emily Stonebrook, John David Spencer, Joshua R Watson","doi":"10.1542/pir.2023-006017","DOIUrl":"10.1542/pir.2023-006017","url":null,"abstract":"<p><p>Despite the American Academy of Pediatrics guidelines for the evaluation, treatment, and management of urinary tract infections (UTIs), UTI diagnosis and management remains challenging for clinicians. Challenges with acute UTI management stem from vague presenting signs and symptoms, diagnostic uncertainty, limitations in laboratory testing, and selecting appropriate antibiotic therapy in an era with increasing rates of antibiotic-resistant uropathogens. Recurrent UTI management remains difficult due to an incomplete understanding of the factors contributing to UTI, when to assess a child with repeated infections for kidney and urinary tract anomalies, and limited prevention strategies. To help reduce these uncertainties, this review provides a comprehensive overview of UTI epidemiology, risk factors, diagnosis, treatment, and prevention strategies that may help pediatricians overcome the challenges associated with acute and recurrent UTI management.</p>","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Shieh, Taylor R Schoenheit, Shane T Mallon, Emily J Mathias
{"title":"Acute Weakness in a Toddler with Sickle Cell Disease.","authors":"Andrew Shieh, Taylor R Schoenheit, Shane T Mallon, Emily J Mathias","doi":"10.1542/pir.2022-005746","DOIUrl":"10.1542/pir.2022-005746","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristen Kyler, M Olivia Titus, Morgan Sims, Carrie Busch
{"title":"Acute Unilateral Lower Extremity Weakness in a 7-year-old Girl.","authors":"Kristen Kyler, M Olivia Titus, Morgan Sims, Carrie Busch","doi":"10.1542/pir.2021-005386","DOIUrl":"10.1542/pir.2021-005386","url":null,"abstract":"","PeriodicalId":20007,"journal":{"name":"Pediatrics in review","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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