With the aim of finding novel compounds with good antimicrobial activity to counteract drug resistance, a new series of quinazolinones featuring thiourea and thiazole groups was synthesized through the reaction of 4-amino-N-(4-oxo-2-phenyl-1, 2-dihydroquinazolin-3(4H)-yl)benzamide with methyl isothiocyanate and subsequent treatment with dialkyl acetylene dicarboxylate. All synthesized compounds were characterized by spectroscopic data and elemental analysis. The antimicrobial activity of synthesized compounds was evaluated against two bacteria strains (Escherichia coli PTCC1330; Staphylococcus aureus PTCC 1431) and two fungi strains (Aspergillus niger PTCC5010; Candida albicans ATCC 10231). Almost all products exhibited good antibacterial and antifungal activities which indicated that insertion of thiourea and thiazolidine moieties considerably increased the antimicrobial properties of quinazolinones. Therefore, these compounds can be good candidates for clinical treatments, avoiding possible drug resistance problems in humans.
{"title":"Synthesis and antimicrobial evaluation of new quinazolinone derivatives containing thiourea and thiazolidine moieties","authors":"Farzaneh Yazdan Kushkoo , Hojatollah Khabazzadeh , Moj Khaleghi","doi":"10.1080/10426507.2025.2461044","DOIUrl":"10.1080/10426507.2025.2461044","url":null,"abstract":"<div><div>With the aim of finding novel compounds with good antimicrobial activity to counteract drug resistance, a new series of quinazolinones featuring thiourea and thiazole groups was synthesized through the reaction of 4-amino-N-(4-oxo-2-phenyl-1, 2-dihydroquinazolin-3(4H)-yl)benzamide with methyl isothiocyanate and subsequent treatment with dialkyl acetylene dicarboxylate. All synthesized compounds were characterized by spectroscopic data and elemental analysis. The antimicrobial activity of synthesized compounds was evaluated against two bacteria strains (<em>Escherichia coli</em> PTCC1330; <em>Staphylococcus aureus</em> PTCC 1431) and two fungi strains (<em>Aspergillus niger</em> PTCC5010; <em>Candida albicans</em> ATCC 10231). Almost all products exhibited good antibacterial and antifungal activities which indicated that insertion of thiourea and thiazolidine moieties considerably increased the antimicrobial properties of quinazolinones. Therefore, these compounds can be good candidates for clinical treatments, avoiding possible drug resistance problems in humans.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 152-163"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A series of new hybrid systems containing furan-2-one and chromen-4-thione fragments were synthesized for the first time and characterized by elemental analysis, IR, NMR (1H,13C, NOESY) spectroscopy and X-ray structural analysis. It was shown that (E)-5-aryl-3-[(4-thioxo-4H-chromen-3-yl)methylene]furan-2(3H)-ones exist only in the E-configuration. Their in vitro antibacterial activity against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus was studied in liquid nutrient media by the serial dilution method. The results showed that (E)-5-(4-chlorophenyl)-3-[(4-thioxo-4H-chromen-3-yl)methylene]furan-2(3H)-one and (E)-5-(4-methoxyphenyl)-3-[(4-thioxo-4H-chromen-3-yl)methylene]furan-2(3H)-one demonstrated the best in vitro antibacterial properties against the bacterial culture Escherichia coli.
{"title":"Synthesis, crystal structure and evaluation of antibacterial activity of new hybrid systems containing furan-2-one and chromen-4-thione fragments","authors":"Ekaterina Mikhailovna Arzyamova , Alevtina Yur’evna Yegorova","doi":"10.1080/10426507.2025.2461042","DOIUrl":"10.1080/10426507.2025.2461042","url":null,"abstract":"<div><div>A series of new hybrid systems containing furan-2-one and chromen-4-thione fragments were synthesized for the first time and characterized by elemental analysis, IR, NMR (<sup>1</sup>H,<sup>13</sup>C, NOESY) spectroscopy and X-ray structural analysis. It was shown that (<em>E</em>)-5-aryl-3-[(4-thioxo-4<em>H</em>-chromen-3-yl)methylene]furan-2(3<em>H</em>)-ones exist only in the <em>E</em>-configuration. Their <em>in vitro</em> antibacterial activity against <em>Escherichia coli</em>, <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> was studied in liquid nutrient media by the serial dilution method. The results showed that (<em>E</em>)-5-(4-chlorophenyl)-3-[(4-thioxo-4<em>H</em>-chromen-3-yl)methylene]furan-2(3<em>H</em>)-one and (<em>E</em>)-5-(4-methoxyphenyl)-3-[(4-thioxo-4<em>H</em>-chromen-3-yl)methylene]furan-2(3<em>H</em>)-one demonstrated the best <em>in vitro</em> antibacterial properties against the bacterial culture <em>Escherichia coli</em>.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 164-173"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1080/10426507.2025.2456204
Ahmed Ali Jasim , Ahmed Hamdi Mirghani , Ahmed Saleem Otaiwi , Ahmet Coşkun , Hakan Tahtaci , Saban Uysal
In this study, we synthesized six novel oxime ligands derived from substituted 1,3,4-thiadiazoles, along with their corresponding monomeric transition metal complexes involving Co2+, Ni2+, and Cu2+ ions. Comprehensive structural characterizations were then performed to analyze these compounds. To achieve this, 4-(chloroacetyl) diphenyl ether was synthesized by reacting diphenyl ether with chloroacetyl chloride using a Friedel–Crafts reaction. The starting oxime compound, (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, was synthesized by reacting 4-(chloroacetyl) diphenyl ether with butyl nitrite in a 1:1 molar ratio, with HCl as the catalyst. The target oxime compounds were subsequently synthesized by reacting substituted 2-amino-1,3,4-thiadiazole derivatives with (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, following established procedures from the literature. The structural characterizations of all synthesized organic compounds were carried out using elemental analysis, FTIR spectroscopy, 1H and 13C NMR spectroscopy, and mass spectrometry. The target complexes were synthesized by reacting the ligands with MCl2·nH2O salts (M = Co2+, Ni2+, Cu2+). Their structures were confirmed using FTIR spectroscopy, magnetic susceptibility measurements, elemental analysis, and ICP-OES.
在这项研究中，我们合成了六种新的肟配体，这些配体来源于取代的1,3,4-噻二唑，以及它们相应的单体过渡金属配合物，包括Co2+， Ni2+和Cu2+离子。然后对这些化合物进行了全面的结构表征。为了实现这一目标，采用Friedel-Crafts反应，将二苯醚与氯乙酰氯反应合成4-（氯乙酰）二苯醚。以4-（氯乙酰）二苯醚和亚硝酸盐丁酯为原料，以盐酸为催化剂，摩尔比为1:1，合成了起始肟化合物(E)- n -羟基-2-氧-2-（4-苯氧苯基）乙酰咪酰氯。目标肟化合物随后通过取代的2-氨基-1,3,4-噻二唑衍生物与(E)- n -羟基-2-氧-2-（4-苯氧苯基）乙酰咪酰氯反应合成，按照文献中建立的程序。采用元素分析、FTIR光谱、1H和13C核磁共振谱和质谱对合成的有机化合物进行了结构表征。配体与mc2·nH2O盐（M = Co2+, Ni2+, Cu2+）反应合成目标配合物。通过FTIR光谱、磁化率测量、元素分析和ICP-OES对其结构进行了证实。
{"title":"Synthesis and characterization of diphenylether-based oxime ligands containing unilaterally substituted 1,3,4-thiadiazole groups and investigation of their some transition metal complexes","authors":"Ahmed Ali Jasim , Ahmed Hamdi Mirghani , Ahmed Saleem Otaiwi , Ahmet Coşkun , Hakan Tahtaci , Saban Uysal","doi":"10.1080/10426507.2025.2456204","DOIUrl":"10.1080/10426507.2025.2456204","url":null,"abstract":"<div><div>In this study, we synthesized six novel oxime ligands derived from substituted 1,3,4-thiadiazoles, along with their corresponding monomeric transition metal complexes involving Co<sup>2+</sup>, Ni<sup>2+</sup>, and Cu<sup>2+</sup> ions. Comprehensive structural characterizations were then performed to analyze these compounds. To achieve this, 4-(chloroacetyl) diphenyl ether was synthesized by reacting diphenyl ether with chloroacetyl chloride using a Friedel–Crafts reaction. The starting oxime compound, (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, was synthesized by reacting 4-(chloroacetyl) diphenyl ether with butyl nitrite in a 1:1 molar ratio, with HCl as the catalyst. The target oxime compounds were subsequently synthesized by reacting substituted 2-amino-1,3,4-thiadiazole derivatives with (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, following established procedures from the literature. The structural characterizations of all synthesized organic compounds were carried out using elemental analysis, FTIR spectroscopy, <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, and mass spectrometry. The target complexes were synthesized by reacting the ligands with MCl<sub>2</sub>·nH<sub>2</sub>O salts (M = Co<sup>2+</sup>, Ni<sup>2+</sup>, Cu<sup>2+</sup>). Their structures were confirmed using FTIR spectroscopy, magnetic susceptibility measurements, elemental analysis, and ICP-OES.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 133-143"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1080/10426507.2025.2457458
Ainaa Nadiah Abd Halim , Zainab Ngaini
Thiourea and triazine are heteroatom scaffolds that have been intensively employed for structural modification, particularly in the development of new drugs and the exploration of new applications. Recent advances have initiated the concept of merging these two moieties, maximizing the potential and enhancing the properties. This review is a comprehensive compilation highlighting the various synthesis pathways of the compound comprised of both thiourea and triazine scaffolds expressed in the form of fused triazinethione as well as mono-, bis-, and tris-thiourea-triazine structures. The produced compounds indefinitely showed the potential to be applied to various fields and industries. While this compilation majorly highlighted the biological capabilities of the thiourea–triazine compounds, a glimpse of other material chemistry applications was also included on the basis of the respective compound as documented by precedent literature. Therefore, this review is significant for structural modification in the field of synthetic chemistry for intended applications.
{"title":"Review on the synthesis of thiourea-triazine hybrid derivatives and its applications primarily in biological context","authors":"Ainaa Nadiah Abd Halim , Zainab Ngaini","doi":"10.1080/10426507.2025.2457458","DOIUrl":"10.1080/10426507.2025.2457458","url":null,"abstract":"<div><div>Thiourea and triazine are heteroatom scaffolds that have been intensively employed for structural modification, particularly in the development of new drugs and the exploration of new applications. Recent advances have initiated the concept of merging these two moieties, maximizing the potential and enhancing the properties. This review is a comprehensive compilation highlighting the various synthesis pathways of the compound comprised of both thiourea and triazine scaffolds expressed in the form of fused triazinethione as well as <em>mono</em>-, <em>bis</em>-, and <em>tris</em>-thiourea-triazine structures. The produced compounds indefinitely showed the potential to be applied to various fields and industries. While this compilation majorly highlighted the biological capabilities of the thiourea–triazine compounds, a glimpse of other material chemistry applications was also included on the basis of the respective compound as documented by precedent literature. Therefore, this review is significant for structural modification in the field of synthetic chemistry for intended applications.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 109-132"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1080/10426507.2025.2463459
Kiran Arora , J. M. Khurana
A study regarding the deoxygenation of chalcogenide dioxides (selenones, tellurones and sulfones) to the respective chalcogenides using magnesium and methanol as reductant, has been reported. The magnesium catalyzed reaction was initiated by mercuric chloride at ambient temperature. The reactions are fast and are proceeding by Single electron transfer (SET) from magnesium. No desulphurization, deselenization or detellurization was observed in any case. The halogens attached to the aryl ring remained unaffected under these conditions.
{"title":"Reduction of organic sulfones, selenones and tellurones using magnesium and methanol as reductant","authors":"Kiran Arora , J. M. Khurana","doi":"10.1080/10426507.2025.2463459","DOIUrl":"10.1080/10426507.2025.2463459","url":null,"abstract":"<div><div>A study regarding the deoxygenation of chalcogenide dioxides (selenones, tellurones and sulfones) to the respective chalcogenides using magnesium and methanol as reductant, has been reported. The magnesium catalyzed reaction was initiated by mercuric chloride at ambient temperature. The reactions are fast and are proceeding by Single electron transfer (SET) from magnesium. No desulphurization, deselenization or detellurization was observed in any case. The halogens attached to the aryl ring remained unaffected under these conditions.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 174-180"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1080/10426507.2024.2437009
A. S. Shalfia Judit , R. Feyolah Herin , S. Sebastiammal , J. Henry , M. Santhosh , M. Santhamoorthy
Hydroxyapatite (HAp) is the most common calcium phosphate used for biomedical applications. The properties such as size, shape, and crystalline structure of HAp depends on the different precursor materials and also various preparation methods such as dry method, wet method, and high temperature process. This review summarizes various preparation methods of HAp for biomedical applications like drug delivery, bone tissue engineering, bioimaging, and antimicrobial. The various preparation methods affects the product yield, reaction kinetics, and reaction temperature. The size, shape, and morphology of the HAp can also be tailored through various bio and chemical methods.
{"title":"Chemical and natural synthesis of hydroxyapatite nanoparticles for biomedical applications: a review","authors":"A. S. Shalfia Judit , R. Feyolah Herin , S. Sebastiammal , J. Henry , M. Santhosh , M. Santhamoorthy","doi":"10.1080/10426507.2024.2437009","DOIUrl":"10.1080/10426507.2024.2437009","url":null,"abstract":"<div><div>Hydroxyapatite (HAp) is the most common calcium phosphate used for biomedical applications. The properties such as size, shape, and crystalline structure of HAp depends on the different precursor materials and also various preparation methods such as dry method, wet method, and high temperature process. This review summarizes various preparation methods of HAp for biomedical applications like drug delivery, bone tissue engineering, bioimaging, and antimicrobial. The various preparation methods affects the product yield, reaction kinetics, and reaction temperature. The size, shape, and morphology of the HAp can also be tailored through various bio and chemical methods.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 1","pages":"Pages 12-36"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1080/10426507.2024.2435943
Jiaqi Wang , Ying Zhang , Qingshan Rong , Yan Shi , Zhiwei Yao
Nitrogen and phosphorus are one of the most common Group 15 elements. The chemistry of nitrogen and phosphorus is very important in the field of catalysis. Three types of nitride containing NiMo/γ-Al2O3 catalysts were synthesized using different loading-nitriding sequences and oxide precursor types for dry reforming of methane (DRM). The active components (Ni2Mo3N and Ni/Mo2N) firstly reacted with CO2, transforming into NiO and MoO2. They were then carburized with CH4 to produce Ni/Mo2C during the DRM process. From that point on, a redox cycle, viz. NiO/MoO2 ⇆ Ni/Mo2C, occurred during the DRM reaction. The low activity of nitriding-first NiMo nitride catalyst can be attributed to bulk oxidation. The observed gradual decline in performance of loading-first Ni/Mo nitride catalyst was due to coking. Noticeably, the loading-first NiMo nitride catalyst can demonstrate superiority in both activity and resistance to coking, which was due to its strong metal–Al2O3 interaction and high metal dispersion.
{"title":"On the catalytic nature of nitrided NiMo/γ-Al2O3 catalysts for dry reforming of methane","authors":"Jiaqi Wang , Ying Zhang , Qingshan Rong , Yan Shi , Zhiwei Yao","doi":"10.1080/10426507.2024.2435943","DOIUrl":"10.1080/10426507.2024.2435943","url":null,"abstract":"<div><div>Nitrogen and phosphorus are one of the most common Group 15 elements. The chemistry of nitrogen and phosphorus is very important in the field of catalysis. Three types of nitride containing NiMo/γ-Al<sub>2</sub>O<sub>3</sub> catalysts were synthesized using different loading-nitriding sequences and oxide precursor types for dry reforming of methane (DRM). The active components (Ni<sub>2</sub>Mo<sub>3</sub>N and Ni/Mo<sub>2</sub>N) firstly reacted with CO<sub>2</sub>, transforming into NiO and MoO<sub>2</sub>. They were then carburized with CH<sub>4</sub> to produce Ni/Mo<sub>2</sub>C during the DRM process. From that point on, a redox cycle, viz. NiO/MoO<sub>2</sub> ⇆ Ni/Mo<sub>2</sub>C, occurred during the DRM reaction. The low activity of nitriding-first NiMo nitride catalyst can be attributed to bulk oxidation. The observed gradual decline in performance of loading-first Ni/Mo nitride catalyst was due to coking. Noticeably, the loading-first NiMo nitride catalyst can demonstrate superiority in both activity and resistance to coking, which was due to its strong metal–Al<sub>2</sub>O<sub>3</sub> interaction and high metal dispersion.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 1","pages":"Pages 46-53"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1080/10426507.2025.2452211
Qinqin Li , Xiaochun Tian , Ao Sun , Chengyu Wang , Kangle Ding
The study systematically conducted orthogonal and univariate experiments to determine the optimal parameters for pyridine removal using vulcanized oil shale. The findings revealed that the key determinants of pyridine adsorption onto vulcanized oil shale included the pH level of the pyridine solution, contact time, initial pyridine concentration, and the quantity of vulcanized oil shale introduced into the system. Under optimal adsorption conditions, the vulcanized oil shale achieved a 48.00% adsorption efficiency and an equilibrium adsorption capacity of 4.83 mg·g−1. In contrast, the untreated oil shale exhibited a comparatively reduced adsorption efficiency of 22.88% under its respective optimal conditions. The research further examined the adsorption kinetics and isothermal adsorption models for both types of oil shale. The kinetic data indicated that pyridine adsorption followed a pseudo-second-order model. The pyridine adsorption isotherms for both oil shale and vulcanized oil shale were best described by the Freundlich model, compared to the Langmuir model. These findings provide significant insights into the utilization of vulcanized oil shale for the efficient treatment of low-concentration pyridine wastewater, potentially contributing to environmental remediation and pollution control strategies.
{"title":"Experimental investigation of pyridine removal using vulcanized oil shale","authors":"Qinqin Li , Xiaochun Tian , Ao Sun , Chengyu Wang , Kangle Ding","doi":"10.1080/10426507.2025.2452211","DOIUrl":"10.1080/10426507.2025.2452211","url":null,"abstract":"<div><div>The study systematically conducted orthogonal and univariate experiments to determine the optimal parameters for pyridine removal using vulcanized oil shale. The findings revealed that the key determinants of pyridine adsorption onto vulcanized oil shale included the pH level of the pyridine solution, contact time, initial pyridine concentration, and the quantity of vulcanized oil shale introduced into the system. Under optimal adsorption conditions, the vulcanized oil shale achieved a 48.00% adsorption efficiency and an equilibrium adsorption capacity of 4.83 mg·g<sup>−1</sup>. In contrast, the untreated oil shale exhibited a comparatively reduced adsorption efficiency of 22.88% under its respective optimal conditions. The research further examined the adsorption kinetics and isothermal adsorption models for both types of oil shale. The kinetic data indicated that pyridine adsorption followed a pseudo-second-order model. The pyridine adsorption isotherms for both oil shale and vulcanized oil shale were best described by the Freundlich model, compared to the Langmuir model. These findings provide significant insights into the utilization of vulcanized oil shale for the efficient treatment of low-concentration pyridine wastewater, potentially contributing to environmental remediation and pollution control strategies.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 1","pages":"Pages 90-100"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1080/10426507.2024.2435939
Mohamed Ibrahim Hegab
The skeleton of thiopyran is a remarkable structural system that belongs to sulfur-containing six-membered heterocycles. It acts as a major building block in a large class of medicinal compounds, and synthetic compounds exhibiting a broad variety of significant biological and pharmaceutical activities. This review article highlights the chemistry of thiopyran derivatives, synthesis, and pharmaceutical activities.
{"title":"A review on chemical and biological studies of thiopyran derivatives","authors":"Mohamed Ibrahim Hegab","doi":"10.1080/10426507.2024.2435939","DOIUrl":"10.1080/10426507.2024.2435939","url":null,"abstract":"<div><div>The skeleton of thiopyran is a remarkable structural system that belongs to sulfur-containing six-membered heterocycles. It acts as a major building block in a large class of medicinal compounds, and synthetic compounds exhibiting a broad variety of significant biological and pharmaceutical activities. This review article highlights the chemistry of thiopyran derivatives, synthesis, and pharmaceutical activities.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 1","pages":"Pages 1-11"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1080/10426507.2024.2444665
Sonia Khanna
Over the past few years, the relevance of ions and molecules with biological activity has increased. Search for new molecules capable of coordinating these analytes has gained interest in research. Thiosemicarbazones are an important member of N,S-donor ligands possessing versatile bonding modes, and biological applications as antiviral, antibacterial and anti-cancer. The complexing ability can be tuned by introducing substituents of different nature. Their potency as an intermediate to synthesize pharmaceutic and bioactive materials enhances their extensive application in the area of medicinal chemistry. The easy method of usage, ability for modulation and integration in different applications makes them versatile. Thiosemicarbazones are reported as chemosensors for different cations and anions.
{"title":"Analysis of thiosemicarbazones as an effective spectrophotometric chemosensor","authors":"Sonia Khanna","doi":"10.1080/10426507.2024.2444665","DOIUrl":"10.1080/10426507.2024.2444665","url":null,"abstract":"<div><div>Over the past few years, the relevance of ions and molecules with biological activity has increased. Search for new molecules capable of coordinating these analytes has gained interest in research. Thiosemicarbazones are an important member of N,S-donor ligands possessing versatile bonding modes, and biological applications as antiviral, antibacterial and anti-cancer. The complexing ability can be tuned by introducing substituents of different nature. Their potency as an intermediate to synthesize pharmaceutic and bioactive materials enhances their extensive application in the area of medicinal chemistry. The easy method of usage, ability for modulation and integration in different applications makes them versatile. Thiosemicarbazones are reported as chemosensors for different cations and anions.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 1","pages":"Pages 37-45"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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