Pub Date : 2022-10-24DOI: 10.14314/polimery.2022.9.2
M. Jurewicz
New legal regulations concerning nanomaterials in the scope of the legal certainty principle were discussed. Commission Regulation (EU) 2018/1881 of 03/12/2018 amending the REACH regulation with regard to Annexes I, III, VI-XII is the first normative act on chemicals that sets out the requirements for the registration of nanoforms of substances. The new requirements for nanomaterials will serve to implement the principle of legal certainty in this area. The presented analysis of the introduced amendments to the annexes to the REACH regulation indicates some shortcomings of the new legal regulations.
{"title":"New legal regulations on nanoforms of substances in the context of the legal certainty principle","authors":"M. Jurewicz","doi":"10.14314/polimery.2022.9.2","DOIUrl":"https://doi.org/10.14314/polimery.2022.9.2","url":null,"abstract":"New legal regulations concerning nanomaterials in the scope of the legal certainty principle were discussed. Commission Regulation (EU) 2018/1881 of 03/12/2018 amending the REACH regulation with regard to Annexes I, III, VI-XII is the first normative act on chemicals that sets out the requirements for the registration of nanoforms of substances. The new requirements for nanomaterials will serve to implement the principle of legal certainty in this area. The presented analysis of the introduced amendments to the annexes to the REACH regulation indicates some shortcomings of the new legal regulations.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41759478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-24DOI: 10.14314/polimery.2022.10.2
G. Budzik, M. Zaborniak, Jakub Roczniak
The methodology and measurement results of the machine part produced directly from the 3D-CAD numerical model are presented. Representative additive techniques based on polymer processing were used. The accuracy of replication of CAD numerical models was assessed in terms of both external surface analysis and part volume.
{"title":"Analysis of the influence of selected Slicer parameters on the mapping accuracy in the FFF method","authors":"G. Budzik, M. Zaborniak, Jakub Roczniak","doi":"10.14314/polimery.2022.10.2","DOIUrl":"https://doi.org/10.14314/polimery.2022.10.2","url":null,"abstract":"The methodology and measurement results of the machine part produced directly from the 3D-CAD numerical model are presented. Representative additive techniques based on polymer processing were used. The accuracy of replication of CAD numerical models was assessed in terms of both external surface analysis and part volume.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43815126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-29DOI: 10.14314/polimery.2022.9.4
Jianfa Wang, Zhengzhou Gu, Jie Zhao, Susu Zhang, Peiyao Li, Chao Meng, J. Sui, Xiaoyi Zhang, Shaokai Hu, Jiaying Pan, Junyi Li
The influence of UV radiation on the physical and mechanical properties of polyurethane resins and three-proof polyurethane coatings was examined. Changes of mechanical properties and the gloss of resins and coatings were determined. The structure of materials was confirmed using scanning microscopy SEM and Fourier transform infrared spectroscopy FTIR; thermogravimetric TGA and DTG studies were also performed. It turned out that the gloss of finished protective coatings was worse than the gloss of individual resins, and aging significantly lowered these values (from 81.3° to 8.9° in case of resins and from 61.1° to 2.8° in case of coatings after 1200 hours of irradiation). Tensile strength of resins decreased constantly during aging while their elongation at break decreased than increased reaching minimum at exposure time of 100 hours. In case of coatings, both tensile strength and elongation at break firstly decreased than increased reaching minimum at exposure time of 800 hours; after long exposure time, more than 1200 hours, these properties decreased again.
{"title":"Aging behavior of three-proof polyurethane coatings under UV radiation","authors":"Jianfa Wang, Zhengzhou Gu, Jie Zhao, Susu Zhang, Peiyao Li, Chao Meng, J. Sui, Xiaoyi Zhang, Shaokai Hu, Jiaying Pan, Junyi Li","doi":"10.14314/polimery.2022.9.4","DOIUrl":"https://doi.org/10.14314/polimery.2022.9.4","url":null,"abstract":"The influence of UV radiation on the physical and mechanical properties of polyurethane resins and three-proof polyurethane coatings was examined. Changes of mechanical properties and the gloss of resins and coatings were determined. The structure of materials was confirmed using scanning microscopy SEM and Fourier transform infrared spectroscopy FTIR; thermogravimetric TGA and DTG studies were also performed. It turned out that the gloss of finished protective coatings was worse than the gloss of individual resins, and aging significantly lowered these values (from 81.3° to 8.9° in case of resins and from 61.1° to 2.8° in case of coatings after 1200 hours of irradiation). Tensile strength of resins decreased constantly during aging while their elongation at break decreased than increased reaching minimum at exposure time of 100 hours. In case of coatings, both tensile strength and elongation at break firstly decreased than increased reaching minimum at exposure time of 800 hours; after long exposure time, more than 1200 hours, these properties decreased again.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42282751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-23DOI: 10.14314/polimery.2022.9.5
Sajjad Ali, Dr. Muhammad Owais Raza Siddiqui, S. M. Noman, Tahreem Beg, Danmei Sun
The influence of class C fly ash as a substitute for mineral aggregate on the stability and density of asphalt mixtures containing 3.5−6 wt% of bitumen was investigated. For the fly ash concentration (in relation to the replaced aggregate) 25, 50, 75 and 100 wt%, the optimal asphalt content (OAC) was determined, respectively, 5.75, 4.82, 4.42, 4.4 and 4 wt%. The stability increased with the increase in the content of fly ash. The results confirm the possibility of replacing mineral aggregates with fly ash.
{"title":"Class C fly ash as a substitute for mineral fillers in asphalt mixtures","authors":"Sajjad Ali, Dr. Muhammad Owais Raza Siddiqui, S. M. Noman, Tahreem Beg, Danmei Sun","doi":"10.14314/polimery.2022.9.5","DOIUrl":"https://doi.org/10.14314/polimery.2022.9.5","url":null,"abstract":"The influence of class C fly ash as a substitute for mineral aggregate on the stability and density of asphalt mixtures containing 3.5−6 wt% of bitumen was investigated. For the fly ash concentration (in relation to the replaced aggregate) 25, 50, 75 and 100 wt%, the optimal asphalt content (OAC) was determined, respectively, 5.75, 4.82, 4.42, 4.4 and 4 wt%. The stability increased with the increase in the content of fly ash. The results confirm the possibility of replacing mineral aggregates with fly ash.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43689459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-21DOI: 10.14314/POLIMERY.2000.050
B. Samujło, R. Sikora
Medium-density PE (MFI, 0.712 g/10 min) was modified with Mg(OH)2, FR-20 grade, particle size 2.5 mm. Antiblocking and lubricating agents, 020—04, 020—15 and Lifoslip 220 PE were added as PE concetrates. Experimental extrusions in a Brabender Plastic-Corder (PLV 151 type) were carried out at screw speed 0.75 s-1, three-heating-zones temperatures 160oC, 170oC and 170oC, extruder head temperature 170oC, and extrusion velocity 1.72 mm/s. The pressure in the extruder head, the turning moment measured on the extruder screw, and the flow rate rose as the Mg(OH)2 content was increased (Figs. 1-3). With the Lifoslip agent, the pressure and the turning moment attained the lowest values. At high Mg(OH)2 contents, 57.5 and 60%, the pressure and the turning moment had values close to those attained with other auxiliary agents.
{"title":"The course of Mg(OH)2 modified polyethylene extusion process","authors":"B. Samujło, R. Sikora","doi":"10.14314/POLIMERY.2000.050","DOIUrl":"https://doi.org/10.14314/POLIMERY.2000.050","url":null,"abstract":"Medium-density PE (MFI, 0.712 g/10 min) was modified with Mg(OH)2, FR-20 grade, particle size 2.5 mm. Antiblocking and lubricating agents, 020—04, 020—15 and Lifoslip 220 PE were added as PE concetrates. Experimental extrusions in a Brabender Plastic-Corder (PLV 151 type) were carried out at screw speed 0.75 s-1, three-heating-zones temperatures 160oC, 170oC and 170oC, extruder head temperature 170oC, and extrusion velocity 1.72 mm/s. The pressure in the extruder head, the turning moment measured on the extruder screw, and the flow rate rose as the Mg(OH)2 content was increased (Figs. 1-3). With the Lifoslip agent, the pressure and the turning moment attained the lowest values. At high Mg(OH)2 contents, 57.5 and 60%, the pressure and the turning moment had values close to those attained with other auxiliary agents.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48219773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-20DOI: 10.14314/polimery.2022.9.3
Hao Huang, Yanhua Cai, Lisha Zhao
The influence of phenylacetic acid hydrazide (NAPAH) derivative content, melt temperature (170−200°C) and cooling rate (1−20°C/min) on poly (L-lactide) (PLLA) nucleation were investigated. Increasing the content of NAPAH (0.5−3.0 wt.%) had a positive effect on PLLA crystallization, while an increase in the cooling rate and heating temperature had a negative effect. In the case of isothermal crystallization carried out for a long time (180 min), the melting process depended only on the crystallization temperature. NAPAH also influenced the cold crystallization temperature, reduced thermal stability and improved PLLA processability (MFR).
{"title":"Thermal properties and processability of modified poly(L-lactide): the role of phenylacetic acid hydrazide derivative","authors":"Hao Huang, Yanhua Cai, Lisha Zhao","doi":"10.14314/polimery.2022.9.3","DOIUrl":"https://doi.org/10.14314/polimery.2022.9.3","url":null,"abstract":"The influence of phenylacetic acid hydrazide (NAPAH) derivative content, melt temperature (170−200°C) and cooling rate (1−20°C/min) on poly (L-lactide) (PLLA) nucleation were investigated. Increasing the content of NAPAH (0.5−3.0 wt.%) had a positive effect on PLLA crystallization, while an increase in the cooling rate and heating temperature had a negative effect. In the case of isothermal crystallization carried out for a long time (180 min), the melting process depended only on the crystallization temperature. NAPAH also influenced the cold crystallization temperature, reduced thermal stability and improved PLLA processability (MFR).","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48620890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-20DOI: 10.14314/polimery.2022.9.1
D. Kolasa, A. Stępkowska, J. Wróbel, K. Samsonowska, A. Kaszuba, K. Wróbel, J. Lach
Artykuł stanowi kontynuację przeglądu obowiązujących aktów prawnych nt. bezpieczeństwa produktów wprowadzanych na rynek Unii Europejskiej. Przegląd, dotyczący (w części II) zasad kontroli substancji szkodliwych w produktach rynkowych (w szczególności w materiałach i wyrobach przeznaczonych do kontaktu z żywnością) wykonanych z gumy lub zawierających elementy gumowe, obejmuje zarówno akty prawne i rekomendacje UE, jak i akty krajowe transponujące regulacje unijne do prawa polskiego w tym zakresie.
{"title":"Wymagania dotyczące zawartości substancji szkodliwych w wyrobach rynkowych z tworzyw sztucznych i gumy. Cz. II. Produkty gumowe, w szczególności materiały i wyroby z gumy przeznaczone do kontaktu z żywnością","authors":"D. Kolasa, A. Stępkowska, J. Wróbel, K. Samsonowska, A. Kaszuba, K. Wróbel, J. Lach","doi":"10.14314/polimery.2022.9.1","DOIUrl":"https://doi.org/10.14314/polimery.2022.9.1","url":null,"abstract":"Artykuł stanowi kontynuację przeglądu obowiązujących aktów prawnych nt. bezpieczeństwa produktów wprowadzanych na rynek Unii Europejskiej. Przegląd, dotyczący (w części II) zasad kontroli substancji szkodliwych w produktach rynkowych (w szczególności w materiałach i wyrobach przeznaczonych do kontaktu z żywnością) wykonanych z gumy lub zawierających elementy gumowe, obejmuje zarówno akty prawne i rekomendacje UE, jak i akty krajowe transponujące regulacje unijne do prawa polskiego w tym zakresie.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46921371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-09DOI: 10.14314/polimery.2022.7.8
A. Tiwari, V. Tiwari, N. Verma, Anita Singh, Manish Kumar, V. Saini, B. Sahoo, Deepak Kaushik, R. Verma, Suresh Sagadevan
Because of the present pandemic researchers are seeking for phytocandidates that can inhibit or stop SARS-CoV-2. The main protease (Mpro) of SARS-CoV-2 and spike glycoprotein (S) are both suppressed by bioactive compounds found in plants that work by docking them together. The Mpro proteins 6LU7 (complex with an inhibitor N3) and 5C3N (space group C2221) were employed in docking research. PyRx and AutoDock Vina software were used as docking engine. 22 identified phytoconstituents were selected from IMPPAT, a manually curated database, on the basis of their antiviral effects. Docking studies showed that phytoconstituents β-amyrin (-8.4 kcal/mol), withaferin A (-8.3 kcal/mol), oleanolic acid (-7.8 kcal/mol), and patentiflorin A (-8.1 kcal/mol) had the best results against 5C3N Mpro protein whereas kuwanon L (-7.1 kcal/mol), β-amyrin (-6.9 kcal/mol), oleanolic acid (-6.8 kcal/mol), cucurbitacin D (-6.5 kcal/mol), and quercetin (-6.5 kcal/mol) against 6LU7 Mpro protein. All the compounds were examined for their ADMET characteristics using SwissDock. Present research reports that the phytoconstituents along with docking score will be helpful for future drug development against Covid-19.
由于目前的大流行，研究人员正在寻找能够抑制或阻止SARS-CoV-2的植物候选物。SARS-CoV-2的主要蛋白酶(Mpro)和刺突糖蛋白(S)都受到植物中发现的生物活性化合物的抑制，这些活性化合物通过将它们对接在一起起作用。Mpro蛋白6LU7(配合抑制剂N3)和5C3N(空间群C2221)进行对接研究。对接引擎采用PyRx和AutoDock Vina软件。从人工整理的IMPPAT数据库中选择22种已确定的植物成分，根据它们的抗病毒作用。对接研究表明，植物成分β-amyrin (-8.4 kcal/mol)、withaferin A (-8.3 kcal/mol)、齐墩果酸(-7.8 kcal/mol)和patentiflorin A (-8.1 kcal/mol)对5C3N Mpro蛋白的抑制效果最好，而kuwanon L (-7.1 kcal/mol)、β-amyrin (-6.9 kcal/mol)、齐墩果酸(-6.8 kcal/mol)、葫芦素D (-6.5 kcal/mol)和槲皮素(-6.5 kcal/mol)对6LU7 Mpro蛋白的抑制效果最好。使用SwissDock检测所有化合物的ADMET特性。目前的研究报告表明，植物成分与对接评分将有助于未来抗Covid-19药物的开发。
{"title":"Molecular docking studies on the phytoconstituents as therapeutic leads against SARS-CoV-2","authors":"A. Tiwari, V. Tiwari, N. Verma, Anita Singh, Manish Kumar, V. Saini, B. Sahoo, Deepak Kaushik, R. Verma, Suresh Sagadevan","doi":"10.14314/polimery.2022.7.8","DOIUrl":"https://doi.org/10.14314/polimery.2022.7.8","url":null,"abstract":"Because of the present pandemic researchers are seeking for phytocandidates that can inhibit or stop SARS-CoV-2. The main protease (Mpro) of SARS-CoV-2 and spike glycoprotein (S) are both suppressed by bioactive compounds found in plants that work by docking them together. The Mpro proteins 6LU7 (complex with an inhibitor N3) and 5C3N (space group C2221) were employed in docking research. PyRx and AutoDock Vina software were used as docking engine. 22 identified phytoconstituents were selected from IMPPAT, a manually curated database, on the basis of their antiviral effects. Docking studies showed that phytoconstituents β-amyrin (-8.4 kcal/mol), withaferin A (-8.3 kcal/mol), oleanolic acid (-7.8 kcal/mol), and patentiflorin A (-8.1 kcal/mol) had the best results against 5C3N Mpro protein whereas kuwanon L (-7.1 kcal/mol), β-amyrin (-6.9 kcal/mol), oleanolic acid (-6.8 kcal/mol), cucurbitacin D (-6.5 kcal/mol), and quercetin (-6.5 kcal/mol) against 6LU7 Mpro protein. All the compounds were examined for their ADMET characteristics using SwissDock. Present research reports that the phytoconstituents along with docking score will be helpful for future drug development against Covid-19.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":"18 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41259017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-08DOI: 10.14314/polimery.2022.7.6
Alberto Baeza-Campuzano, Javier Morales-Castillo, V. Castaño
Using the example of acrylonitrile-butadiene-styrene (ABS) copolymer, the effect of the gap (thread) diameter for five printing velocity at 230°C on the thread temperature and velocity at the nozzle exit was investigated using the ANSYS Fluent simulation program. It was shown that the change of the gap diameter had a significant impact on the tested parameters.
{"title":"The influence of the gap diameter on the polymer thread temperature and velocity at the exit of the 3D printer nozzle","authors":"Alberto Baeza-Campuzano, Javier Morales-Castillo, V. Castaño","doi":"10.14314/polimery.2022.7.6","DOIUrl":"https://doi.org/10.14314/polimery.2022.7.6","url":null,"abstract":"Using the example of acrylonitrile-butadiene-styrene (ABS) copolymer, the effect of the gap (thread) diameter for five printing velocity at 230°C on the thread temperature and velocity at the nozzle exit was investigated using the ANSYS Fluent simulation program. It was shown that the change of the gap diameter had a significant impact on the tested parameters.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46283257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-07DOI: 10.14314/polimery.2022.7.7
E. Dluska, A. Markowska-Radomska, Patryk Skowroński
Among biopolymers, pH-responsive ones have much potential for drug delivery systems by exploiting the pH gradient between physiological and pathological states. In this paper multiple emulsions with a pH-responsive biopolymer for controlled drug delivery in brain tumor treatment were discussed. The characteristic and rheological properties of multiple emulsions, biopolymer adsorption, zeta potential, and release processes were examined. The results showed higher drug release rates in the acidic tumor microenvironment compared to the simulated conditions of normal cells.
{"title":"A pH-responsive biopolymer-based multiple emulsion prepared in a helicoidal contactor for chemotherapeutics delivery","authors":"E. Dluska, A. Markowska-Radomska, Patryk Skowroński","doi":"10.14314/polimery.2022.7.7","DOIUrl":"https://doi.org/10.14314/polimery.2022.7.7","url":null,"abstract":"Among biopolymers, pH-responsive ones have much potential for drug delivery systems by exploiting the pH gradient between physiological and pathological states. In this paper multiple emulsions with a pH-responsive biopolymer for controlled drug delivery in brain tumor treatment were discussed. The characteristic and rheological properties of multiple emulsions, biopolymer adsorption, zeta potential, and release processes were examined. The results showed higher drug release rates in the acidic tumor microenvironment compared to the simulated conditions of normal cells.","PeriodicalId":20319,"journal":{"name":"Polimery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45203724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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