Pub Date : 2019-08-28DOI: 10.37321/ujmh.2018.02-03
Юрий Заседа
Objective: to establish the eff ectiveness of Сefpotek (cefpodoxime) and Сlabel (clarithromycin) drugs in the treatment of chronic prostate infl ammation in the stage of pronounced exacerbation caused by nonspecifi c infectious agents and infections of the mycoplasma and chlamydia groups.Materials and methods. The study was conducted in a prospective design on parallel groups. The study contingent consisted of 60 patients of the “Men’s Health Clinic”, suff ering from chronic prostatitis in state of pronounced exacerbation. The following research methods were used: sonographic examination of the prostate gland, bacteriological examination of the ejaculate, analysis of ejaculate and PCR diagnostics of specifi c infections.The results of the study. A diff erentiated course of etiotropic therapy was carried out. In case of non-specifi c prostatitis: oral administration of the drug “Cefpotek” (cefpodoxim) 1 tablet (200 mg) 2 times a day for a course of 14 days with the possibility of extending the course to 28 days. With specifi c prostatitis: oral administration of the drug “Clabel” (clarithromycin) 1 tablet (500 mg) 2 times a day for a course of 14 days.Conclusions. In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by nonspecifi c infectious agents using oral administration of the drug “Сefpotek”, the full eff ectiveness was achieved in range from 83.3% to 96.6% of observations.In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by infectious agents of the mycoplasma and chlamydia groups using oral administration of the drug “Clabel”, the full eff ectiveness was achieved in the range from 80.0% to 86.6% of observations (regardless of features of combinations of specifi c mixed infections).
{"title":"THE ANALYSIS OF EFFICACY OF “CEFPOTEC” AND “CLABEL” PREPARATIONS IN TREATMENT OF SPECIFIC AND NONSPECIFIC PROSTATITIS","authors":"Юрий Заседа","doi":"10.37321/ujmh.2018.02-03","DOIUrl":"https://doi.org/10.37321/ujmh.2018.02-03","url":null,"abstract":"Objective: to establish the eff ectiveness of Сefpotek (cefpodoxime) and Сlabel (clarithromycin) drugs in the treatment of chronic prostate infl ammation in the stage of pronounced exacerbation caused by nonspecifi c infectious agents and infections of the mycoplasma and chlamydia groups.Materials and methods. The study was conducted in a prospective design on parallel groups. The study contingent consisted of 60 patients of the “Men’s Health Clinic”, suff ering from chronic prostatitis in state of pronounced exacerbation. The following research methods were used: sonographic examination of the prostate gland, bacteriological examination of the ejaculate, analysis of ejaculate and PCR diagnostics of specifi c infections.The results of the study. A diff erentiated course of etiotropic therapy was carried out. In case of non-specifi c prostatitis: oral administration of the drug “Cefpotek” (cefpodoxim) 1 tablet (200 mg) 2 times a day for a course of 14 days with the possibility of extending the course to 28 days. With specifi c prostatitis: oral administration of the drug “Clabel” (clarithromycin) 1 tablet (500 mg) 2 times a day for a course of 14 days.Conclusions. In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by nonspecifi c infectious agents using oral administration of the drug “Сefpotek”, the full eff ectiveness was achieved in range from 83.3% to 96.6% of observations.In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by infectious agents of the mycoplasma and chlamydia groups using oral administration of the drug “Clabel”, the full eff ectiveness was achieved in the range from 80.0% to 86.6% of observations (regardless of features of combinations of specifi c mixed infections).","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129482701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-28DOI: 10.37321/ujmh.2019.01-01
Юрий Заседа
In order to evaluate the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis, 72 patients of the Men’s Health clinic in Kyiv were examined. According to the survey results, 2 symmetric groups of 23 patients were formed. The main group was treated according to the model: antibiotic therapy, auxiliary pharmacotherapy (venotonic drugs and enzymes), local physiotherapy and diet therapy with the inclusion of cowberry and blueberry pastes. The control group received a similar treatment, but without changing the diet.Evaluating the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis shows that patients treated with the inclusion of homogenized cowberry and blueberry pastes in the diet demonstrate a lower intensity of symptoms of chronic bacterial prostatitis (according to the I-PSS scale) 3 months after treatment, namely: “urination urgency” and “subjective reduction in the quality of life” (p=0.03).
{"title":"ASSESSMENT OF THE EFFICIENCY OF THE APPLICATION OF THE COWBERRY AND BLUEBARRY PASTE IN COMPLEX TREATMENT OF CHRONIC BACTERIAL PROSTATITIS","authors":"Юрий Заседа","doi":"10.37321/ujmh.2019.01-01","DOIUrl":"https://doi.org/10.37321/ujmh.2019.01-01","url":null,"abstract":"In order to evaluate the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis, 72 patients of the Men’s Health clinic in Kyiv were examined. According to the survey results, 2 symmetric groups of 23 patients were formed. The main group was treated according to the model: antibiotic therapy, auxiliary pharmacotherapy (venotonic drugs and enzymes), local physiotherapy and diet therapy with the inclusion of cowberry and blueberry pastes. The control group received a similar treatment, but without changing the diet.Evaluating the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis shows that patients treated with the inclusion of homogenized cowberry and blueberry pastes in the diet demonstrate a lower intensity of symptoms of chronic bacterial prostatitis (according to the I-PSS scale) 3 months after treatment, namely: “urination urgency” and “subjective reduction in the quality of life” (p=0.03).","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116145785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-28DOI: 10.37321/ujmh.2019.01-02
Юрий Заседа, Руслан Соломенный, Фарид Шихалиев
Relevance. Chronic persistent viral infections are a category of andro-urological problems that currently have no defi nite solutions.The aim of the study is to evaluate the eff ectiveness of treatment of chronic infl ammatory diseasesof the prostate gland (persistent viral mixed infections: combinations of herpes simplex virus (first and second types) and human papilloma virus using the drug “Allokin-alpha”(Alloferonum)), in comparison with recombinant human interferon-2b.Materials and methods. The study was conducted on a contingent of 60 patients of the clinic “Men’s Health”, Kyiv. The study design suggested the use of 2 parallel groups of 30 patients receiving treatment according to diff erent therapeutic models.The results of the study. When comparing therapeutic models using parenteral administration of Alloferonum in the composition of the drug “Allokin-alpha” and parenteral administration of recombinant human interferon-2b in parallel groups of patients suff ering from chronic persistent mixed infections, a number of diff erences regarding serological and clinical effi cacy and long-term eff ects were found.Findings. The eff ectiveness of the elimination of chronic persistent viral mixed infections for Alloferonum was 66,7%, for recombinant human interferon-2b in - 40%. The catamnestic eff ects of therapeutic models also diff ered. For Alloferonum 6 months after the course of treatment, the recovery of serological activity of viruses occurred in 13,4% of patients, the return of systemic clinical manifestations was observed in 23,3% of patients, the return of symptoms of specifi c prostatitis - in 10,0% of patients. For recombinant human interferon-2b, similar fi gures were 23,0%, 33,3% and 20,0%, respectively.
{"title":"THE EXPERIENCE OF THE USE OF ALLOKINE-ALPHA IN TREATMENT OF CHRONIC PERSISTING VIRAL MIXT-INFECTIONS IN MEN","authors":"Юрий Заседа, Руслан Соломенный, Фарид Шихалиев","doi":"10.37321/ujmh.2019.01-02","DOIUrl":"https://doi.org/10.37321/ujmh.2019.01-02","url":null,"abstract":"Relevance. Chronic persistent viral infections are a category of andro-urological problems that currently have no defi nite solutions.The aim of the study is to evaluate the eff ectiveness of treatment of chronic infl ammatory diseasesof the prostate gland (persistent viral mixed infections: combinations of herpes simplex virus (first and second types) and human papilloma virus using the drug “Allokin-alpha”(Alloferonum)), in comparison with recombinant human interferon-2b.Materials and methods. The study was conducted on a contingent of 60 patients of the clinic “Men’s Health”, Kyiv. The study design suggested the use of 2 parallel groups of 30 patients receiving treatment according to diff erent therapeutic models.The results of the study. When comparing therapeutic models using parenteral administration of Alloferonum in the composition of the drug “Allokin-alpha” and parenteral administration of recombinant human interferon-2b in parallel groups of patients suff ering from chronic persistent mixed infections, a number of diff erences regarding serological and clinical effi cacy and long-term eff ects were found.Findings. The eff ectiveness of the elimination of chronic persistent viral mixed infections for Alloferonum was 66,7%, for recombinant human interferon-2b in - 40%. The catamnestic eff ects of therapeutic models also diff ered. For Alloferonum 6 months after the course of treatment, the recovery of serological activity of viruses occurred in 13,4% of patients, the return of systemic clinical manifestations was observed in 23,3% of patients, the return of symptoms of specifi c prostatitis - in 10,0% of patients. For recombinant human interferon-2b, similar fi gures were 23,0%, 33,3% and 20,0%, respectively.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133113508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-28DOI: 10.37321/ujmh.2018.02-02
Юрий Заседа
Relevance. The spectrum of combined mechanisms of action of PRP-therapy, LISWT and LNP therapy suggests the clinical eff ect for patients with fi broplastic penile induration, which currently does not have conservative therapies that have suffi cient effi cacy.The aim of the study was to determine the effi cacy of combined PRP-therapy with intracavernous activation of growth factors by LISWT method + LNP and ICA pharmacotherapy in treatment of fi broplastic penile induction.Design. The study group comprised 23 patients of the Men’s Health Clinic in Kyiv, suff ering from fi broplastic penile inducing (Peyronie’s disease, ICD-10: N48.6) with erectile dysfunction.Results of the study. A 6-month follow-up observation showed a reduction of pain during erection, a signifi cant improvement in erectile function, a total regression of the areas less than 25 mm2 and a signifi cant decrease in the density and area of the induration areas that over 25 mm2.Conclusions. It has been established that the therapeutic model of the combined use of PRP-therapy with intracavernous activation of growth factors by LISWT method + LOD + ICA in the treatment of fi broplastic penile induration, shows a pronounced clinical eff ect, which makes this therapeutic model a promising option for conservative correction of pain and erectile dysfunction in fi broplastic penile induration.
{"title":"EXPERIENCE OF PREMATURE EJACULATION CORRECTION BY COMBINED THERAPY OF PLATELET-RICH PLASMA AND LOW-INTENSITY SHOCK-WAVE THERAPY","authors":"Юрий Заседа","doi":"10.37321/ujmh.2018.02-02","DOIUrl":"https://doi.org/10.37321/ujmh.2018.02-02","url":null,"abstract":"Relevance. The spectrum of combined mechanisms of action of PRP-therapy, LISWT and LNP therapy suggests the clinical eff ect for patients with fi broplastic penile induration, which currently does not have conservative therapies that have suffi cient effi cacy.The aim of the study was to determine the effi cacy of combined PRP-therapy with intracavernous activation of growth factors by LISWT method + LNP and ICA pharmacotherapy in treatment of fi broplastic penile induction.Design. The study group comprised 23 patients of the Men’s Health Clinic in Kyiv, suff ering from fi broplastic penile inducing (Peyronie’s disease, ICD-10: N48.6) with erectile dysfunction.Results of the study. A 6-month follow-up observation showed a reduction of pain during erection, a signifi cant improvement in erectile function, a total regression of the areas less than 25 mm2 and a signifi cant decrease in the density and area of the induration areas that over 25 mm2.Conclusions. It has been established that the therapeutic model of the combined use of PRP-therapy with intracavernous activation of growth factors by LISWT method + LOD + ICA in the treatment of fi broplastic penile induration, shows a pronounced clinical eff ect, which makes this therapeutic model a promising option for conservative correction of pain and erectile dysfunction in fi broplastic penile induration.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114643402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-28DOI: 10.37321/ujmh.2018.02-01
Юрий Заседа
Relevance. The spectrum of combined mechanisms of action of PRP-therapy, LISWT and LNP therapy suggests the clinical eff ect for patients with fi broplastic penile induration, which currently does not have conservative therapies that have suffi cient effi cacy.The aim of the study was to determine the effi cacy of combined PRP-therapy with intracavernous activation of growth factors by LISWT method + LNP and ICA pharmacotherapy in treatment of fi broplastic penile induction.Design. The study group comprised 23 patients of the Men’s Health Clinic in Kyiv, suff ering from fi broplastic penile inducing (Peyronie’s disease, ICD-10: N48.6) with erectile dysfunction.Results of the study. A 6-month follow-up observation showed a reduction of pain during erection, a signifi cant improvement in erectile function, a total regression of the areas less than 25 mm2 and a signifi cant decrease in the density and area of the induration areas that over 25 mm2. Conclusions. It has been established that the therapeutic model of the combined use of PRP-therapy with intracavernous activation of growth factors by LISWT method + LOD + ICA in the treatment of fi broplastic penile induration, shows a pronounced clinical eff ect, which makes this therapeutic model a promising option for conservative correction of pain and erectile dysfunction in fi broplastic penile induration.
{"title":"EXPERIENCE OF COMBINING PLATELET-RICH AUTOPLASM THERAPY AND LOW-INTENSITY SHOCK-WAVE THERAPY IN TREATMENT OF PEYRONIE’S DISEASE","authors":"Юрий Заседа","doi":"10.37321/ujmh.2018.02-01","DOIUrl":"https://doi.org/10.37321/ujmh.2018.02-01","url":null,"abstract":"Relevance. The spectrum of combined mechanisms of action of PRP-therapy, LISWT and LNP therapy suggests the clinical eff ect for patients with fi broplastic penile induration, which currently does not have conservative therapies that have suffi cient effi cacy.The aim of the study was to determine the effi cacy of combined PRP-therapy with intracavernous activation of growth factors by LISWT method + LNP and ICA pharmacotherapy in treatment of fi broplastic penile induction.Design. The study group comprised 23 patients of the Men’s Health Clinic in Kyiv, suff ering from fi broplastic penile inducing (Peyronie’s disease, ICD-10: N48.6) with erectile dysfunction.Results of the study. A 6-month follow-up observation showed a reduction of pain during erection, a signifi cant improvement in erectile function, a total regression of the areas less than 25 mm2 and a signifi cant decrease in the density and area of the induration areas that over 25 mm2. Conclusions. It has been established that the therapeutic model of the combined use of PRP-therapy with intracavernous activation of growth factors by LISWT method + LOD + ICA in the treatment of fi broplastic penile induration, shows a pronounced clinical eff ect, which makes this therapeutic model a promising option for conservative correction of pain and erectile dysfunction in fi broplastic penile induration.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124138385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-28DOI: 10.37321/ujmh.2018.01-01
Y. Zasieda, R. Solomianyi, Farid Shykhaliiev
In order to compare the clinical eff ect of platelet rich plasma-therapy and local negative pressure-therapy on the background of pharmacotherapy with Icariin and combined platelet rich plasma-therapy in combination with shock-wave therapy and vacuum device therapy on the background of pharmacotherapy with Icariin in the treatment of erectile dysfunction of arterial and arterial-venous origin, 50 patients of the «Men’s Health» Clinic (Kiev) were examined with using clinical, laboratory and sonographic methods. Based on the results of the study, the high eff ectiveness of platelet rich plasma-therapy, shock-wave therapy and vacuum device -therapy and Icariin combinationsuse in the arterial and arterial-venous erectile dysfunction therapy in comparison with platelet rich plasma-therapy and vacuum device therapy and Icariin. According to our data intracavernosus activation of plate-cells was conducted by shock-wave method in a first time ever.
{"title":"THE EXPERIENCE OF COMBINED APPLICATION OF PLATELET-RICH PLASMA THERAPY AND SHOCK-WAVE THERAPY IN TREATMENT OF ERECTILE DYSFUNCTION OF VASCULAR ORIGIN","authors":"Y. Zasieda, R. Solomianyi, Farid Shykhaliiev","doi":"10.37321/ujmh.2018.01-01","DOIUrl":"https://doi.org/10.37321/ujmh.2018.01-01","url":null,"abstract":"In order to compare the clinical eff ect of platelet rich plasma-therapy and local negative pressure-therapy on the background of pharmacotherapy with Icariin and combined platelet rich plasma-therapy in combination with shock-wave therapy and vacuum device therapy on the background of pharmacotherapy with Icariin in the treatment of erectile dysfunction of arterial and arterial-venous origin, 50 patients of the «Men’s Health» Clinic (Kiev) were examined with using clinical, laboratory and sonographic methods. Based on the results of the study, the high eff ectiveness of platelet rich plasma-therapy, shock-wave therapy and vacuum device -therapy and Icariin combinationsuse in the arterial and arterial-venous erectile dysfunction therapy in comparison with platelet rich plasma-therapy and vacuum device therapy and Icariin. According to our data intracavernosus activation of plate-cells was conducted by shock-wave method in a first time ever.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114669409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-28DOI: 10.37321/ujmh.2018.01-02
Юрий Заседа
The aim of the study was to analyze the effi cacy of the drug “Macmiror” (active substance – nifuratel) in the treatment of chronic specifi c bacterial fi brous and calculous prostatitis associated with trichomoniasis and candidiasis.Materials and methods. The study was conducted on 50 patients of the “Clinic “Men’s Health”, suff ering from chronic specifi c bacterial fi brous and calculous prostatitis (mixed infection: trichomonadial-bacterial-candidiasis associates of various structure). As methods of research, in addition to the standard complex, the following were chosen: IN POUCH TV-test; PCR method; sonographic examination ofthe prostate and spermogram.Results of the study. Patients who completed the study were treated with chronic specifi c bacterial fi brous and calculous prostatitis (N41.1) for 14 days, according to the following therapeutic model: oral administration of nifuratel as part of the “Macmiror” preparation at a total dosage of 1200 mg per day (6 tablets of 200 mg) divided into 3 doses and physiotherapy.Conclusions. A general (in relation to diff erent types and combinations of infectious agents) of the therapeutic model has been established at a level of 71% to 100%. Treatment had absolute (clinical and laboratory) effi cacy against isolated Candida spp.; absolute clinical effi cacy and 71-85% laboratory effi cacy against isolated Trichomonas vaginalis; 92% clinical and 76-84% laboratory effi cacy against the combination of these infectious agents; 92% clinical and 80% laboratory effi cacy against the combination of these infectious agents and non-specifi c bacterial fl ora, as the etiological factors of chronic specifi c bacterial prostatitis.
{"title":"EXPERIENCE OF NIFURATEL USAGE IN COMPLEX TREATMENT OF CHRONIC SPECIFIC BACTERIAL FIBROUSE AND CALCULOUS PROSTATITIS ASSOCIATED WITH TRICHOMONIASIS AND CANDIDOSIS","authors":"Юрий Заседа","doi":"10.37321/ujmh.2018.01-02","DOIUrl":"https://doi.org/10.37321/ujmh.2018.01-02","url":null,"abstract":"The aim of the study was to analyze the effi cacy of the drug “Macmiror” (active substance – nifuratel) in the treatment of chronic specifi c bacterial fi brous and calculous prostatitis associated with trichomoniasis and candidiasis.Materials and methods. The study was conducted on 50 patients of the “Clinic “Men’s Health”, suff ering from chronic specifi c bacterial fi brous and calculous prostatitis (mixed infection: trichomonadial-bacterial-candidiasis associates of various structure). As methods of research, in addition to the standard complex, the following were chosen: IN POUCH TV-test; PCR method; sonographic examination ofthe prostate and spermogram.Results of the study. Patients who completed the study were treated with chronic specifi c bacterial fi brous and calculous prostatitis (N41.1) for 14 days, according to the following therapeutic model: oral administration of nifuratel as part of the “Macmiror” preparation at a total dosage of 1200 mg per day (6 tablets of 200 mg) divided into 3 doses and physiotherapy.Conclusions. A general (in relation to diff erent types and combinations of infectious agents) of the therapeutic model has been established at a level of 71% to 100%. Treatment had absolute (clinical and laboratory) effi cacy against isolated Candida spp.; absolute clinical effi cacy and 71-85% laboratory effi cacy against isolated Trichomonas vaginalis; 92% clinical and 76-84% laboratory effi cacy against the combination of these infectious agents; 92% clinical and 80% laboratory effi cacy against the combination of these infectious agents and non-specifi c bacterial fl ora, as the etiological factors of chronic specifi c bacterial prostatitis.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134002688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-28DOI: 10.37321/ujmh.2018.01-03
Юрий Заседа
Relevance. Symptoms of the lower urinary tract take a central role in outpatient urology, primarily due to the high prevalence in the general population.Objective: To analyze the eff ectiveness of suppositories “Proxelan” in the treatment of symptoms of the lower urinary tract associated with chronic prostatitis and benign prostatic hyperplasia of the mild degree.Design. The study was conducted in a prospective design on a contingent of 100 male patients who underwent outpatient treatment at the “Men’s Health Clinic” LLC. Patients were divided into 2 groups, depending on the presence in the treatment regimen of rectal suppositories “Proxelan”.Results of the study. The fi ndings on the diff erences in the intensity of symptom manifestations in the structure of lower urinary tract symptoms, according to the I-PSS scale, indicate that there is a signifi cant clinical eff ect on the symptoms in general for both treatment groups. Diff erences between the eff ect in the study groups range from moderate to minor.Conclusions. It has been established that the inclusion in the treatment regimen of rectal suppositories “Proxelan” allows to increase the clinical eff ect with respect to some indicators, namely: frequent urination and weakening of the urine stream. In addition, signifi cantly improve the quality of life of patients with symptoms of the lower urinary tract.
{"title":"APPLICATION OF “PROXELAN” SUPPOSITORY IN TREATMENT OF SYMPTOMS OF LOWER URINARY WAYS ASSOCIATED WITH CHRONIC PROSTATITE AND BENIGN HYPERPLASIA OF THE PROSTATE GLAND","authors":"Юрий Заседа","doi":"10.37321/ujmh.2018.01-03","DOIUrl":"https://doi.org/10.37321/ujmh.2018.01-03","url":null,"abstract":"Relevance. Symptoms of the lower urinary tract take a central role in outpatient urology, primarily due to the high prevalence in the general population.Objective: To analyze the eff ectiveness of suppositories “Proxelan” in the treatment of symptoms of the lower urinary tract associated with chronic prostatitis and benign prostatic hyperplasia of the mild degree.Design. The study was conducted in a prospective design on a contingent of 100 male patients who underwent outpatient treatment at the “Men’s Health Clinic” LLC. Patients were divided into 2 groups, depending on the presence in the treatment regimen of rectal suppositories “Proxelan”.Results of the study. The fi ndings on the diff erences in the intensity of symptom manifestations in the structure of lower urinary tract symptoms, according to the I-PSS scale, indicate that there is a signifi cant clinical eff ect on the symptoms in general for both treatment groups. Diff erences between the eff ect in the study groups range from moderate to minor.Conclusions. It has been established that the inclusion in the treatment regimen of rectal suppositories “Proxelan” allows to increase the clinical eff ect with respect to some indicators, namely: frequent urination and weakening of the urine stream. In addition, signifi cantly improve the quality of life of patients with symptoms of the lower urinary tract.","PeriodicalId":204320,"journal":{"name":"Men’s Health, Gender and Psychosomatic Medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131327444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-28DOI: 10.37321/ujmh.2018.01-04
Юрий Заседа
Relevance. The development of reproductive technologies and techniques, the establishment of biological and immunological aspects of the reproductive process and the expansion of the use of biochemical research in routine practice, has led to the increasing attention to androurological disorders.The aim of the study is a comparative analysis of the effectiveness of the therapeutic model using a combination of Serenoa repens extract (in the composition of the drug “Prostamol Uno”), selective antibiotic therapy and physiotherapy in the treatment of excretory-toxic infertility associated with chronic prostatitis.Materials and methods. The study was conducted in a prospective study on parallel groups. The contingent of the study comprised 100 patients of the Clinic “Men’s Health” (Kiev), suff ering from chronic prostatitis and undergoing outpatient treatment for fertility disorders.Results of the study. A comparison of the eff ectiveness of the therapeutic model using a combination of Serenoa repens extract (as part of the Prostamol Uno preparation), selective antibiotic therapy and physiotherapy, and a similar model without prescribing Prostamol Uno for the treatment of excretory-toxic infertility associated with chronic prostatitis.Comparison criteria were the data of the expanded spermogram, the clinical questionnaire I-PSS and the level of interleukin-18 in the seminal plasma (established by the method of enzyme immunoassay).Conclusions. The data confi rming the greater eff ectiveness of the model with respect to the spermiogram indices, namely: the volume and time of liquefaction of the seminal fluid; the number of spermatozoa in 1 ml of seminal fluid; presence of spermatozoa (group A + B); the number of leukocytes in the fi eld of vision; amount of mucus in the semen.Also, when analyzing the clinical eff ects of the model in question, there are more pronounced changes in the symptoms of prostatitis, namely: rapid urination; weakening of the urine stream; reducing the quality of life; of the overall I-PSS score. The reliable effi cacy of the study model of treatment in normalizing the level of interleukin-18 in plasma of seminal fluid was also established.
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