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The impact of Covid-19 on people under opioid substitution treatment. Covid-19对阿片类药物替代治疗人群的影响。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.092
Georgios Tzeferakos, Sofia Koutelou, Maria Tritari, Marina Skourteli, Christos Kouimtsidis, Konstantinos Kokkolis, Stylianos Stylianidis

Given the aggravation on the general population's quality of life due to covid-19 and the vulnerability of People Who Use Drugs (PWUD) to acute stress, the aim of the current study was to better comprehend the impact of covid-19 on quality of life and mental health of PWUD as well as their drug use patterns. Another study had been conducted prior to the covid-19 outbreak, which assessed quality of life, indicative PTSD symptoms, and drug use patterns of people who were attending an Opioid Substitution Treatment (OST), in Athens, Greece. As a continuation of the aforementioned study, the same variables were assessed in May and June 2020, after the first lockdown measures. 104 patients agreed to participate. The World Health Organization Quality of Life Questionnaire (WHOQOL) and the Post-Traumatic Stress Scale (PCL-C) were used as well as toxicology tests. The only statistically significant outcome was a reduction regarding the dimension referring to the relationship between the individual and their environment. People with low quality of life were found to experience more severe Post- Traumatic Stress Disorder (PTSD) symptoms after lockdown comparing to those with high quality of life. There was also a statistically non-significant increase in PTSD scores before and after lockdown measures. Regarding drug use patterns, the present research reveals an overall decline in drug use during quarantine. There was a statistically significant decrease in opioid (22.3%) and in benzodiazepine (35%) use after lockdown. Also, a statistically significant increase in mean scores of indicative PTSD symptoms of people who decreased opioid use during and after lockdown measures was found. In regards to amphetamine use, research findings underline a non-significant increase in use (8.7%). The pandemic's impact on the life of people on opioid substitution treatment should be taken into consideration and further studies need to be conducted in order to protect this populations' quality of life and maximize the potential benefits such as reduced access to illicit substances.

鉴于2019冠状病毒病(covid-19)对普通人群生活质量的恶化以及吸毒人员(PWUD)对急性应激的脆弱性,本研究的目的是更好地了解covid-19对PWUD生活质量和心理健康的影响以及他们的药物使用模式。在2019冠状病毒病爆发之前进行了另一项研究,该研究评估了希腊雅典参加阿片类药物替代治疗(OST)的人的生活质量、指示性PTSD症状和药物使用模式。作为上述研究的延续,在第一次封锁措施实施后的2020年5月和6月,对相同的变量进行了评估。104名患者同意参与。采用世界卫生组织生活质量问卷(WHOQOL)和创伤后应激量表(PCL-C),并进行毒理学试验。唯一有统计学意义的结果是个体与环境之间关系的维度降低了。研究发现,与生活质量高的人相比,生活质量低的人在封锁后会经历更严重的创伤后应激障碍(PTSD)症状。在封锁措施前后,创伤后应激障碍得分也有统计学上不显著的增加。关于药物使用模式,目前的研究表明,在隔离期间,药物使用总体下降。封锁后,阿片类药物(22.3%)和苯二氮卓类药物(35%)的使用有统计学意义的显著下降。此外,发现在封锁措施期间和之后减少阿片类药物使用的人的指示性创伤后应激障碍症状的平均得分在统计上显着增加。关于安非他明的使用,研究结果强调使用量没有显著增加(8.7%)。应考虑到这一流行病对接受类阿片替代治疗的人的生活的影响,并需要进行进一步的研究,以保护这一人群的生活质量,并最大限度地发挥减少获取非法药物等潜在益处。
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引用次数: 0
Elder financial abuse and the COVID-19 pandemic: A call to action through training programmes? 老年人财务虐待与COVID-19大流行:通过培训规划呼吁采取行动?
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.090
Vaitsa Giannouli, Magda Tsolaki

Within the last decade, there has been a growing debate regarding financial capacity and abuse as one of the most important challenges that older adults are facing in their everyday lives.1 Currently older adults are highly impacted by pre-and post-COVID-19 measures and there is a massive increase in financial exploitation reports involving older adults worldwide,2 an increase that can be attributed to a number of reasons, such as the higher rates of depression among socially isolated seniors (a diagnosis itself linked to abuse, as it can worsen elders' cognitive and physical condition by making them dependent and vulnerable), but also due to of mass redundancies, financial pressure and stress faced by younger family members (childrenandgrandchildren).3 Althoughpriorresearchemphasizedmainlyindividualcognitive aspects (e.g. financial knowledge/self-beliefs/behaviors in the financial decision-making process), the interaction with emotional and socio-cultural factors are not thoroughly examined. Unfortunately, there are scarce organized large-scale research attempts at national and none at international level to focus on financial abuse of elders suffering from different types of neurocognitive disorders as well as healthy elders, not only before the COVID-19 era, but especially during and after COVID-19 health and social crisis.4 In addition to the lack of research neglecting the cross-cultural perspective, there is also a dire need to refocus previous research attempts that mainly examine perceptions of financial abuse with experimental manipulations, not in real world situations and only from the viewpoint of the patient/family, while disregarding the attitudes and education /educational needs of healthcare experts.5 Future research questions that deserve to be examined, but still remain unanswered, are: What are the cognitive-emotional characteristics of elders prone to abuse and of the persons in their social environment? How do medical-psychiatric conditions influence elders financial abuse? What and how do individuals and groups from different social and cultural settings define-perceive financial abuse and the characteristics of the 'offender' and 'victim'? Under what real-life conditions we-as-'guardians' detect and are willing to report elder financial abuse and how can we 'protect' elders? What do we expect from the state, legal systems and the important others to do? What do elders themselves think and feel about financial abuse and how do they react? What is the 'correct reaction/directives'? What are healthcare professionals' attitudes and knowledge on this topic? Could all the above-mentioned points be taught in programmes? All the above will not only give an alternative viewpoint on this hot, complex multifaceted ethical, legal and practical issue (that many of us are concerned with, but at the same time are unwilling to systematically explore), but may assist us in understanding, planning and acting 'appropriately'. For that t

在过去的十年里,关于经济能力和虐待是老年人在日常生活中面临的最重要的挑战之一的争论越来越多目前,老年人受到covid -19之前和之后措施的严重影响,全世界涉及老年人的经济剥削报告大幅增加,2这一增加可归因于许多原因,例如社会孤立的老年人患抑郁症的比例较高(这一诊断本身与虐待有关,因为它会使老年人的认知和身体状况恶化,使他们变得依赖和脆弱),但也与大规模裁员有关。年轻家庭成员(子女和孙辈)面临的经济压力和压力虽然先前的研究主要集中在个人认知方面(如金融知识/自我信念/金融决策过程中的行为),但与情感和社会文化因素的相互作用并没有得到彻底的研究。遗憾的是,无论是在COVID-19时代之前,还是在COVID-19健康和社会危机期间和之后,国内都很少有组织的大规模研究尝试,国际上也没有研究尝试关注对患有不同类型神经认知障碍的老年人以及健康老年人的经济虐待除了缺乏忽视跨文化视角的研究外,还迫切需要重新关注先前的研究尝试,这些研究主要是通过实验操作来检查对财务滥用的看法,而不是在现实世界的情况下,并且只从患者/家庭的角度出发,而忽略了医疗保健专家的态度和教育/教育需求未来值得研究但仍未得到解答的问题是:易受虐待的老年人及其社会环境中的人的认知情感特征是什么?精神疾病如何影响老年人的经济虐待?来自不同社会和文化背景的个人和群体如何定义和感知经济虐待以及“罪犯”和“受害者”的特征?在现实生活中,作为“监护人”的我们在什么情况下会发现并愿意举报老年人的经济虐待行为?我们如何“保护”老年人?我们对国家、法律体系和其他重要机构的期望是什么?长者自己对财务滥用有什么想法和感受?他们如何反应?什么是“正确的反应/指令”?医疗保健专业人员对这个话题的态度和知识是什么?上述所有要点都能在课程中教授吗?以上所述不仅会为这个热点、复杂的多方面的伦理、法律和实践问题(我们许多人都关心,但同时又不愿系统地探索)提供另一种观点,而且可能有助于我们理解、计划和“适当”行动。为了实现这一目标,应该解决不同的问题,并需要结合多种方法(跨文化环境中的混合定量和定性设计)。最后一点可能有助于阐明这个令人困惑的问题的是引入新的统计方法,如多层次分析,它允许同时检查群体层面(社会)和个人层面(老年人)的因素,从而向我们揭示更广泛的背景。防止金融剥削的金融教育方案采用了广泛而适当的实施方法和传播渠道,重点关注目标群体(老年人、家庭成员/照顾者、保健专业人员)的缺陷、优势和需求。由于复杂的社会形势,教育老年人及其照顾者利用现有资源做出合理的财务决策是势在必行的。这些方案已经取得了成功,因为它们不仅提供了向财务顾问咨询财务问题的机会,而且还提供了便于使用的资源(根据老年人和照顾者的阅读水平),而且包括了足够的细节,对规划很有用5 .对于不能使用电脑或不懂电脑的人,可以提供其他选择,例如通过电话或亲自提供服务,小册子,讲义或其他书面材料,或单独的会议和课程定期促进金融教育的目的(通过在线互动和使用线下资源)包括信息,不仅在个人层面,而且在社区层面培养资金管理和预防骗局的知识重新审视现有的研究,并要求对新出现的问题和未探索的领域进行更新,这是研究人员的义务。 那么,现有的教育项目是否足够?当代的经验重新评估将告诉我们,新旧问题将使我们思考下一步该往哪里走。
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引用次数: 1
The role of the Mobile Mental Health Units in mental healthcare delivery in rural areas in Greece: current challenges and prospects. 流动精神保健单位在希腊农村地区提供精神保健服务中的作用:当前的挑战和前景。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.084
Vaios Peritogiannis, Athina Fragouli-Sakellaropoulou, Marios Stavrogiannopoulos, Iliana Filla, Aikaterini Garmpi, Stella Pantelidou, Maria Samakouri

The present paper aims to highlight the importance of Mobile Mental Health Units (MMHUs) in the delivery of mental health services in remote areas in rural Greece. Since the foundation of the first MMHUs in the eighties till nowadays, those services have expanded in many rural areas and there is some evidence that they are effective in the management of patients with severe mental disorders. The care of those patients seems to contribute to a significant reduction in voluntary and involuntary acute admissions and in length of hospital stay. Cost/effectiveness analysis studies have also shown favorable results. Besides their regular clinical work, MMHUs conduct research, such as epidemiologic surveys. Other research explores the care of elderly patients in rural areas and the care of immigrants that permanently reside in Greece. Other research involves the study of psychotic disorders in the rural context, such as the long-term outcome, the patients' functioning, and the long-term treatment with benzodiazepines. Current challenges for MMHUs involve staffing, particularly for those run by public hospitals, and the retainment of highly trained personnel. Other important challenges are related to the aging of the rural population and the refugee/migrant influx. The MMHUs of the islands that initially accept the refugee flow, have already faced an increased number of new referrals. Given the disparities in mental healthcare between rural and urban areas, further enhancement of the MMHUs' operation is required, as well as continuing training of their workforce. Research at the national level is needed and could be the basis for the design and staffing of new services. The establishment of valid and broadly accepted clinical indices to measure treatment outcomes would facilitate research and ensure the recording and evaluation of the MMHUs' work and their effectiveness as well; and would highlight their utility within the contemporary health system.

本文旨在强调流动精神卫生单位(MMHUs)在希腊农村偏远地区提供精神卫生服务方面的重要性。自80年代第一批精神卫生单位成立至今,这些服务已扩展到许多农村地区,有证据表明它们在管理严重精神障碍患者方面是有效的。对这些病人的护理似乎有助于大幅度减少自愿和非自愿的急性住院和住院时间。成本/效益分析研究也显示出有利的结果。除了常规的临床工作外,医务工作者还进行研究,如流行病学调查。其他研究探讨了对农村地区老年患者的护理和对永久居住在希腊的移民的护理。其他研究包括对农村精神疾病的研究,如长期结果、患者的功能和苯二氮卓类药物的长期治疗。妇幼保健单位目前面临的挑战包括人员配备,特别是公立医院的人员配备,以及留住训练有素的人员。其他重要挑战与农村人口老龄化和难民/移民涌入有关。最初接受难民潮的岛屿的居民住家已经面临越来越多的新转介。鉴于农村和城市地区在精神保健方面的差异,需要进一步加强妇幼保健单位的运作,并继续培训其工作人员。需要在国家一级进行研究,并可作为设计和配备新服务人员的基础。建立有效且被广泛接受的临床指标来衡量治疗结果,将有助于研究,并确保对社区卫生单位的工作及其有效性进行记录和评估;并将突出它们在当代卫生系统中的效用。
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引用次数: 4
The effect of COVID-19 pandemic on mental health and quality of life in the Athens area - Greece. 新冠肺炎大流行对雅典地区心理健康和生活质量的影响——希腊。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.095
Eugenia Triantafillou, Panagiotis Tsellos, Nikos Christodoulou, Chara Tzavara, Irina Mrvoljak-Theodoropoulou, George N Christodoulou

This study examines the associations of the COVID -19 pandemic stressors with mental health and quality of life (QoL) of the general population in different demographic areas of Athens. The random sample of the study consisted of 602 participants, 389 (64,6%) women and 213 (35,4%) men residing in Attica (Greece). It was conducted with telephone interviews during the first wave of the pandemic. The instruments used were: World Health Organization Quality of Life Instrument (WHOQOL-BREF), Depression Anxiety Stress Scale (DASS - 21), Body Vigilance Scale (ΒVS), Dimensional Obsessive-Compulsive Scale (Category 1: contamination obsessions -decontamination compulsions) (DOCS) and a set of socio-demographic data and questions on stressors related to the COVID-19 outbreak. A range of statistical analyses were used, including descriptive statistics, examination of the questionnaires' internal consistency, calculating Cronbach's alpha coefficient, as well as multiple linear regression analyses with dependent variables the WHOQOL-BREF, DASS-21, DOCS, and BVS scales. According to the results of our study: a) The greater the extent of negative emotions due to the pandemic and the imposed restrictive measures, such as worry and fear, the higher the score of depression, anxiety, stress, obsessive-compulsive symptomatology, body vigilance and the lower the scores of the WHOQOL domains (Physical Health, Psychological Health, Social Relationships, Environment), b) the fear of being contaminated by the virus seems to have intensified depression-anxiety-stress (DASS-21), obsessive-compulsive (DOCS) and hypochondriacal (BVS) symptomatology. c) The independent variables of depression, stress and anxiety and obsessive - compulsive and hypochondriacal symptomatology were negatively associated with QoL d) The most vulnerable groups in terms of QoL and mental health indicators in our study were those with psychiatric or/and physical illness, the elderly, the unemployed during the lockdown period, those with low educational/ socioeconomic status and those living alone. In conclusion, the negative emotions associated with the COVID-19 outbreak and the imposed restrictive measures had a serious impact on mental health and QoL of the population. This and other similar findings should be taken into account by authorities and decision-makers to prevent and deal with the effects of the pandemic. Unfortunately, the COVID-19 pandemic is still continuing and the imposition of new restrictive measures is considered. This increases the relevance of research like the one presented here.

本研究探讨了雅典不同人口区域普通人群的COVID -19大流行压力源与心理健康和生活质量(QoL)的关系。该研究的随机样本包括602名参与者,其中389名(64.6%)女性和213名(35.5%)男性居住在阿提卡(希腊)。调查是在大流行第一波期间通过电话采访进行的。使用的工具包括:世界卫生组织生活质量量表(WHOQOL-BREF)、抑郁焦虑压力量表(DASS - 21)、身体警觉性量表(ΒVS)、维度强迫症量表(第一类:污染强迫症-去污强迫症)(DOCS)以及一组与COVID-19爆发相关的压力源的社会人口统计数据和问题。采用了一系列统计分析,包括描述性统计、问卷内部一致性检验、Cronbach's alpha系数计算以及以WHOQOL-BREF、DASS-21、DOCS和BVS量表为因变量的多元线性回归分析。根据我们的研究结果:a)由于大流行和实施的限制性措施而产生的负面情绪(如担心和恐惧)程度越大,抑郁、焦虑、压力、强迫症状、身体警觉的得分就越高,WHOQOL域(身体健康、心理健康、社会关系、环境)的得分就越低;b)对病毒污染的恐惧似乎加剧了抑郁-焦虑-压力(DASS-21)。强迫症(DOCS)和疑病症(BVS)症状。c)抑郁、压力和焦虑、强迫和疑病症的自变量与生活质量呈负相关。d)在生活质量和心理健康指标方面,我们研究中最脆弱的群体是精神或/和身体疾病患者、老年人、封锁期间失业者、低文化/社会经济地位者和独居者。综上所述,与新冠肺炎疫情相关的负面情绪和实施的限制措施对人群的心理健康和生活质量产生了严重影响。当局和决策者应考虑到这一发现和其他类似的发现,以预防和应对这一流行病的影响。不幸的是,COVID-19大流行仍在继续,正在考虑实施新的限制措施。这增加了像这里展示的研究的相关性。
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引用次数: 2
Tobacco and Alcohol and Cannabis Experience Questionnaires. Greek translation and test-retest reliability. 烟草、酒精和大麻体验问卷。希腊语翻译和测试-重复可靠性。
Q3 Medicine Pub Date : 2022-12-07 Epub Date: 2022-05-26 DOI: 10.22365/jpsych.2022.082
Konstantinos Kollias, Lida-Alkisti Xenaki, Pentagiotissa Stefanatou, Ilias Vlachos, Stefanos Dimitrakopoulos, Mirjana Selakovic, Irene Ralli, Angeliki-Aikaterini Ntigrintaki, Nikos Stefanis

The Tobacco and Alcohol Questionnaire (TAQ) and the Cannabis Experience Questionnaire (CEQ) are two instruments employed in the evaluation of substance use. The First Episode Psychosis (FEP) study in Athens employed two versions of those questionnaires, as part of a battery of psychometric tools, detecting environmental and genetic factors associated with FEP and addressed specifically to the distinctive characteristics of patients with FEP. The goal of the present study is to present those two versions, regarding their content, their use in international research, their translation in Greek, and their test-retest reliability. The two questionnaires were translated by two independent translators and administered to 32 subjects with FEP twice, in order to be tested for test-retest reliability. Cohen's kappa was used to measure agreement between qualitative variables and ICC between quantitative variables. Significant agreement was found between the two measurements in all items of the TAQ version and almost all items of the CEQ version. Our study is an indication that both translations are reliable, although a more thorough test of their psychometric properties is needed. Both might be used in the Greek research field as part of a broad package of psychometric tools, specifically addressed to patients with FEP.

烟酒问卷(TAQ)和大麻经历问卷(CEQ)是评估药物使用情况的两种工具。雅典的首发精神病(FEP)研究采用了这两种问卷的两个版本,作为一系列心理测量工具的一部分,用于检测与首发精神病相关的环境和遗传因素,并专门针对首发精神病患者的独特特征。本研究的目的是介绍这两个版本的问卷内容、在国际研究中的使用情况、希腊语翻译以及测试-再测试的可靠性。这两份问卷由两名独立译者翻译,并对 32 名 FEP 受试者进行了两次测试,以检验其重测可靠性。科恩卡帕(Cohen's kappa)用于测量定性变量之间的一致性和定量变量之间的 ICC。结果发现,两种测量方法在 TAQ 版本的所有项目和 CEQ 版本的几乎所有项目之间都存在显著的一致性。我们的研究表明,这两种译本都是可靠的,尽管还需要对它们的心理测量特性进行更全面的测试。在希腊的研究领域中,这两种方法都可以作为一套广泛的心理测量工具的一部分来使用,特别是针对 FEP 患者。
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引用次数: 0
Physicians' attitudes towards euthanasia and correlation with their spirituality. 医师对安乐死的态度及其与灵性的关系。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.078
Maria Malliarou, Vasileios Tzenetidis, Iokasti Papathanasiou, Kiriaki Vourdami, Nikolaos Tzenetidis, Athanasios Nikolentzos, Pavlos Sarafis

"Suffering" patients' wishes concerning hastening their own death by means of euthanasia, raised by personal, psychological, social and other motives, are becoming increasingly common. This raises controversies and marks challenges within both the scientific community and the public. The aim of this study is to investigate physicians' attitudes towards euthanasia and its correlation with their spirituality. The final sample consisted of 93 physicians (64.5% men), whose attitudes on euthanasia who were evaluated using Euthanasia Attitude Scale (EAS) and Daily Spiritual Experience Scale (DSES). Physicians' attitudes correlate with their specialty (p=0.037), years of service (p=0.037), as well as the number of end stage patients they cared for and died within the last 12 months (p=0.016). Oncologists and other physicians with similar specialty, those with longer clinical experience and those who treat more end-stage patients to strongly oppose to the above practices. Spirituality, estimated with Daily Spiritual Experience Scale -DSES, is correlated with a negative attitude toward euthanasia (p<0.001). Finally, a considerable gap in physicians' training regarding the management of end stage patients has been highlighted. Physicians are opposed to euthanasia and they require the acquisition of competencies in end-of-life care in order to fulfill their profession's current and future demands in the domain of palliative care.

由于个人、心理、社会和其他动机,“受苦”的病人希望通过安乐死加速自己的死亡,这种情况越来越普遍。这在科学界和公众中都引起了争议和挑战。本研究旨在探讨医师对安乐死的态度及其与灵性的关系。最终样本包括93名医生(男性占64.5%),使用安乐死态度量表(EAS)和日常精神体验量表(DSES)评估他们对安乐死的态度。医生的态度与他们的专业(p=0.037)、服务年限(p=0.037)以及他们在过去12个月内照顾和死亡的末期病人数量(p=0.016)相关。肿瘤学家和其他专业类似的医师、临床经验较长的医师以及治疗终末期患者较多的医师强烈反对上述做法。用每日精神体验量表(dses)评估的精神状态与对安乐死的消极态度相关
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引用次数: 2
The effect of physical activity interventions on cognitive function of older adults: A systematic review of clinical trials. 体育活动干预对老年人认知功能的影响:临床试验的系统回顾。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.060
Viktor Gkotzamanis, Emmanuella Magriplis, Demosthenes Panagiotakos

Prevalence of dementia or of milder form of cognitive impairment is increasing and a pharmaceutical treatment remains pending. These facts underline the need of identifying modifiable factors and targeted interventions that could reduce the incidence or control disease progression. Physical activity (PA) has been shown to have a beneficial effect on cognitive function, however findings to date remain controversial. The aim of this systematic review is to summarize the most recent data from clinical studies investigating the relationship between cognitive impairment and PA in adults older than 60 years of age. For this purpose, PubMed, Scopus and Google Scholar, search was conducted, and a total of thirty-five studies were selected to review. Eleven studies investigated the effect of PA on individuals without cognitive impairment and seven of them presented some significant improvement, mostly on specific cognitive domains and only one in global cognition. Fourteen studies included populations with mild cognitive impairment (MCI) and twelve of them reported significant improvements in cognitive function. The majority of them presented a beneficial effect on global cognition and executive function. Finally, nine studies investigated interventions on populations with a diagnosis of dementia and only four of them showed any cognitive benefit following their interventions. There was no consistent observed association of a specific type of exercise and greater improvement or improvement in certain domains of cognition nor was there a minimum duration of intervention required for the improvements to take effect. In conclusion, the majority of the latest published literature suggests a protective role of PA on cognitive function. People with MCI seem to benefit the most from PA interventions, benefits in people with normal cognition are more subtle and harder to detect, while findings from studies in people with dementia remain contradictory. As findings are not currently in total agreement, further long-term prospective intervention studies are required in order to elucidate the reasons of this heterogeneity.

痴呆症或轻度认知障碍的患病率正在增加,药物治疗仍有待解决。这些事实强调需要确定可改变的因素和有针对性的干预措施,以减少发病率或控制疾病进展。体育活动(PA)已被证明对认知功能有有益的影响,但迄今为止的研究结果仍存在争议。本系统综述的目的是总结最新的临床研究数据,调查60岁以上成人认知障碍和PA之间的关系。为此,我们对PubMed、Scopus和Google Scholar进行了检索,共选取了35篇研究进行综述。11项研究调查了PA对无认知障碍个体的影响,其中7项研究显示了显著的改善,主要是在特定的认知领域,只有1项是在整体认知方面。14项研究包括轻度认知障碍(MCI)人群,其中12项研究报告了认知功能的显著改善。他们中的大多数对整体认知和执行功能有有益的影响。最后,九项研究调查了对诊断为痴呆症的人群的干预措施,其中只有四项在干预后显示出任何认知益处。没有一致的观察到特定类型的运动与某些认知领域的更大改善或改善之间的联系,也没有最短的干预时间要求改善产生效果。总之,大多数最新发表的文献表明PA对认知功能有保护作用。患有轻度认知障碍的人似乎从PA干预中受益最多,对认知正常的人的好处更微妙,更难以察觉,而对痴呆症患者的研究结果仍然矛盾。由于研究结果目前尚未完全一致,需要进一步的长期前瞻性干预研究来阐明这种异质性的原因。
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引用次数: 2
Delusions with content related to COVID-19 pandemic, in non-infected psychiatric hospitalized patients: a six-case series. 非感染精神科住院患者中与COVID-19大流行相关内容的妄想:6例系列
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.088
Christos Mantas, Evgenia Papatheodorou, Maria Elisavet Tsagkaropoulou, Anna Kourti, Georgios Georgiou, Petros Petrikis, Thomas Hyphantis

We briefly present a case series of six patients hospitalized in the Department of Psychiatry, University General Hospital of Ioannina, between the first (starting March 23, 2020) and the second (starting November 7, 2020) lockdown in Greece who presented with COVID-19 - related delusional ideas. All patients had negative PCR prior to admission and no history of COVID-19 infection.The first three of our cases were admitted during the first lockdown, between March 23 and May 4, one involuntary and the other two voluntary. The first one was diagnosed with acute and transient psychosis (F23 - First Episode Psychosis) and the other two with psychotic depression (F32.3). Three additional patients were admitted voluntary after the end of the first lockdown. One was diagnosed with acute and transient psychosis (F23-First Episode Psychosis) and the other two were relapses of a known psychiatric disorder (Bipolar disorder F31.5 and Psychotic depression F32.3). At follow-up six months after discharge all patients were in remission following antipsychotic medication, among other medicines. These cases reveal that COVID-19 pandemic may have an impact on the delusional content of new or preexisting psychotic disorders during the COVID-19 pandemic.

我们简要介绍了在希腊第一次(从2020年3月23日开始)和第二次(从2020年11月7日开始)封锁期间,约阿尼纳大学总医院精神科住院的六名患者的病例系列,这些患者出现了与COVID-19相关的妄想。所有患者入院前PCR阴性,无COVID-19感染史。我们的前三个病例是在3月23日至5月4日的第一次封锁期间入院的,其中一个是非自愿的,另外两个是自愿的。第一个被诊断为急性和短暂性精神病(F23 -首发精神病),另外两个被诊断为精神病性抑郁症(F32.3)。在第一次封锁结束后,又有三名患者自愿入院。其中一人被诊断为急性和短暂性精神病(f23 -首发精神病),另外两人是已知精神障碍的复发(双相情感障碍F31.5和精神病性抑郁症F32.3)。出院后随访6个月,所有患者在服用抗精神病药物和其他药物后均缓解。这些病例表明,COVID-19大流行可能对COVID-19大流行期间新发或已存在的精神障碍的妄想内容产生影响。
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引用次数: 1
Theophrastus's "Anaisthetos" ("The Obtuse Man"): the oldest "phenomenological" description of neurodevelopmental disorders in an adult. 泰奥弗拉斯托斯的《钝器人》(Anaisthetos):对成人神经发育障碍最古老的“现象学”描述。
Q3 Medicine Pub Date : 2022-12-07 DOI: 10.22365/jpsych.2022.079
Artemios Pehlivanidis, Katerina Papanikolaou

Theophrastus (381-278 B.C.), was the first to adopt the term character for the description of distinct inner psychological and moral features of an individual. In his classic book 'Characters' in a simple style wording he analyses some of his contemporary individuals. The character "Αναίσθητος" (Anaisthetos) has been translated in English as "The Obtuse Man" and in Modern Greek both as "Αναίσθητος", meaning lack of appreciation and "Βραδύνους", meaning slowness of mind. Theophrastus' description of this particular character is compatible with the co-occurrence in an adult of two Neurodevelopmental Disorders: the Attention-Deficit Hyperactivity Disorder (ADHD) and the Social Pragmatic Communication Disorder (SPCD), according to the 5th Diagnostic and Statistical Manual of Mental Disorders. Ten out of the twelve statements support the possible occurrence of ADHD while five of them the occurrence of SPCD. The description does not justify a diagnosis of an intellectual disability; therefore, we consider that in the Modern Greek vocabulary the original term «Αναίσθητος» ("Anaisthetos"), meaning lack of appreciation, is more accurately corresponding to this particular Theophrastus's character than "Βραδύνους" ("Obtuse"), which indicates the presence of low intellectual capacities. Also the lack of repetitive and restrictive interests and behaviours excludes Autism Spectrum Disorder as a possible diagnosis. Minor psychiatric disorders and traits according to the Peripatic School were attributed to the lack of rational control over appetites and behavior. Accordingly, «Αναίσθητος» is a phenomenological description of a stigmatizing inappropriate social behavior and the only help that might give is in increasing self-awareness. In our contemporary clinical practice, though, the early recognition and appropriate treatment of Neurodevelopmental Disorders in affected individuals, leads to a better clinical care and may diminish stigmatization. The co-existence of these two disorders in a character in such a different historical context reinforces their validity as diagnostic constructs and provides an example of co-occurrence of Neurodevelopmental Disorders.

泰奥弗拉斯托斯(公元前381-278)是第一个使用“性格”一词来描述个人独特的内在心理和道德特征的人。在他的经典著作《人物》中,他以简单的风格分析了他同时代的一些人物。字符“Αναίσθητος”(Anaisthetos)在英语中被翻译为“愚钝的人”,在现代希腊语中被翻译为“Αναίσθητος”,意思是缺乏欣赏和“Βραδύνους”,意思是思维迟钝。根据第五版《精神疾病诊断与统计手册》,泰奥弗拉斯图斯对这一特殊性格的描述与两种神经发育障碍——注意力缺陷多动障碍(ADHD)和社会实用沟通障碍(SPCD)——在成年人身上同时出现是一致的。12个陈述中有10个支持ADHD的可能发生,而其中5个支持SPCD的发生。该描述不能证明智力残疾的诊断是合理的;因此,我们认为,在现代希腊语词汇中,原始术语“Αναίσθητος”(“Anaisthetos”),意思是缺乏欣赏,比“Βραδύνους”(“钝器”)更准确地对应于这个特殊的泰奥弗拉斯托斯的性格,这表明存在低智力能力。此外,缺乏重复性和限制性的兴趣和行为也排除了自闭症谱系障碍的可能诊断。根据Peripatic学派的说法,轻微的精神疾病和特征是由于缺乏对食欲和行为的理性控制。因此,“Αναίσθητος”是一种对不恰当的社会行为进行污名化的现象学描述,它可能提供的唯一帮助是增强自我意识。然而,在我们当代的临床实践中,早期识别和适当治疗受影响个体的神经发育障碍,可以带来更好的临床护理,并可能减少污名化。在这样一个不同的历史背景下,这两种疾病的共存加强了它们作为诊断结构的有效性,并提供了神经发育障碍共存的一个例子。
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引用次数: 1
Fake news in the age of COVID-19: evolutional and psychobiological considerations. COVID-19时代的假新闻:进化和心理生物学的考虑。
Q3 Medicine Pub Date : 2022-09-19 Epub Date: 2022-07-19 DOI: 10.22365/jpsych.2022.087
Orestis Giotakos

The COVID-19 outbreak has been accompanied by a massive infodemic: an overabundance of information, some accurate and some not. At this pandemic we have seen a large scale of fake news and misinformation, leading to anti-vaccine, anti-mask, and anti-5G protests.1 Fake news is intentionally misleading and deceptive news that is written and published with the intent to damage an entity or a person. They may contain false, misleading, imposter, manipulated or fabricated content. Much of the discourse on fake news conflates three notions, named "information disorders": (a) Misinformation: false information someone shares without knowing it's untrue, (b) Disinformation: false information that's shared with the intention to harm or mislead, and (c) Malinformation: true information that's used to harm others.2 False beliefs generally arise through the same mechanisms that establish accurate beliefs. People appear to encode all new information as if it were true and later tag the information as being either true or false. Different cognitive, social and affective factors lead people to form or endorse misinformed views. The emotional content of the information shared also affects false-belief formation. An angry mood can boost misinformation sharing, while social exclusion, which is likely to induce a negative mood, can increase susceptibility to conspiratorial content.3 As shown by the Illusory Truth Effect, repeated exposure to an article, whether real or fake, increases people's perceptions of its accuracy. In social media, falsehood seems to diffuse significantly farther, faster, deeper, and more broadly than the truth in all categories of information, and the effects are more pronounced for false political news than for false news about terrorism, natural disasters, and science. Moreover, although prior knowledge of a statement leads people to confirm the statement the next time, they see it (confirmation bias), novelty facilitates decision making since it updates our understanding of the world.4 The fitness value of accurate information seems so obvious, while self-deception seems to threaten such hard-won informational gains. Then, why has not it selected out? The American evolutionary biologist and sociobiologist Robert Trivers5 suggested that although our senses have evolved to give us an exquisitely detailed perception of the outside world, as soon as that information hits our brains, it often becomes biased and distorted, usually without conscious effort. Why should this be so? For Trivers, the evolutionary origins of the human propensity for self-deception lie in the adaptive benefits of deceiving others. An animal becomes a better liar when it believes its own lies, or we deceive ourselves the better to deceive others. Deception in animals is the transmission of misinformation by one animal to another, and natural selection favors deceptive signaling when aggression either confers a great benefit to signalers or imposes a great cost to

COVID-19疫情伴随着大规模的信息大流行:信息过多,有些准确,有些不准确。在这次疫情中,我们看到了大规模的假新闻和错误信息,导致了反疫苗、反口罩、反5g的抗议活动假新闻是故意误导和欺骗性的新闻,是为了损害一个实体或个人而编写和发布的。它们可能包含虚假、误导、冒名顶替、操纵或捏造的内容。很多关于假新闻的论述都将三个概念混为一谈,称为“信息紊乱”:(a)虚假信息:有人在不知情的情况下分享的虚假信息;(b)虚假信息:分享的虚假信息意图伤害或误导;(c)恶意信息:用来伤害他人的真实信息错误信念通常是通过建立正确信念的相同机制产生的。人们似乎把所有的新信息都当作真实的来编码,然后再把这些信息标记为真实或虚假。不同的认知、社会和情感因素导致人们形成或赞同错误的观点。共享信息的情感内容也会影响错误信念的形成。愤怒的情绪可以促进错误信息的分享,而社会排斥可能会导致消极情绪,从而增加对阴谋论内容的易感性正如虚幻真相效应所显示的那样,反复接触一篇文章,无论是真的还是假的,都会增加人们对其准确性的认知。在社交媒体上,在所有类别的信息中,虚假信息似乎比真相传播得更远、更快、更深、更广泛,虚假政治新闻的影响比关于恐怖主义、自然灾害和科学的虚假新闻更为明显。此外,尽管先前对一个陈述的了解会导致人们在下次看到它时确认它(确认偏差),但新颖性有助于决策,因为它更新了我们对世界的理解准确信息的适应度价值似乎是如此明显,而自我欺骗似乎威胁到来之不易的信息收益。那么,为什么它没有被选中呢?美国进化生物学家和社会生物学家罗伯特·特里弗斯提出,尽管我们的感官已经进化到能让我们对外部世界有细致入微的感知,但一旦这些信息进入我们的大脑,它往往就会变得有偏见和扭曲,通常是无意识的。为什么会这样呢?在特里夫斯看来,人类自欺倾向的进化起源在于欺骗他人的适应性利益。当动物相信自己的谎言时,它就会成为一个更好的说谎者,或者我们欺骗自己是为了更好地欺骗别人。5 .动物的欺骗行为是一种动物向另一种动物传递错误的信息,当攻击行为要么给信号发送者带来巨大的利益,要么给接收者带来巨大的代价时,自然选择倾向于发出欺骗性的信号在人类中,自欺过程可能对抑郁有保护作用,而抑郁本身可能会减少自欺机制。人类是有偏见的信息寻求者,他们更喜欢接受能证实自己价值观和世界观的信息。也许,这就是为什么围绕COVID-19和疫苗存在神话和阴谋论的原因。我们可能认为,被强调的神经心理过程,可能基于生物学上决定的自我或他人欺骗机制,可能在至少一些与假新闻现象相关的社会行为的发展甚至保护中起作用。这些机制可能支持人类有偏见地寻求信息的倾向,甚至支持假新闻现象的进化持久性然而,在COVID-19大流行等情况下,欺骗自己和他人的本能冲动并非没有风险。相信与covid -19相关的阴谋叙述和假新闻与疫苗接种意愿和感染预防行为呈负相关2019冠状病毒病大流行及其相关的信息大流行放大了潜在的信任问题。对疫苗的犹豫主要是信任问题,而不是信息问题。关于新冠肺炎和疫苗的假新闻、谣言和阴谋论不应仅仅被理解为错误的信念,而且还应被理解为公众焦虑和恐惧的指标。应激接种治疗可以帮助人们为随后的错误信息暴露做好准备,并增加错误信息的检测最后,建议决策者针对不同层次和不同环境培养信息素养技能,摒弃两极分化的态度和行为。
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引用次数: 11
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