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Regarding "Stress management and In Vitro Fertilization (IVF): A pilot randomized controlled trial". 关于“压力管理和体外受精:一项试点随机对照试验”。
Q3 Medicine Pub Date : 2022-04-27 DOI: 10.22365/jpsych.2022.076
S. Komiya, M. Banno, Yuki Itagaki
Koumparou et al.1 recently published a randomized controlled trial (RCT) on the effectiveness of psychological interventions (stress management training, SMT) for women planning in vitro fertilization (IVF). They concluded that while the effect of SMT was limited in terms of IVF outcome, it resulted in a significant reduction of stress levels in infertile patients. Since most women undergoing infertility treatment are exposed to high psychological stress,2 this study may be of great value in demonstrating the need for proactive SMT to maintain infertile women's mental health and motivation to continue treatment. However, we are concerned that the reliability of this RCT has been compromised in several ways. First, the registration of the RCT was not clearly stated. According to The CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines, a prospective registration of the RCT is required, which prevents unnecessary concerns about the bias of results selection.3,4 Second, the lack of specific figures on the background of the participants in the case and control groups risks distorting the RCT results. The article states that there was no significant difference between the two groups. However, since aging and prolonged infertility treatment increase the psychological burden on infertile patients,5 detailed background information is necessary to interpret the results of an RCT accurately. Selection bias could not be determined, which weakened the validity of this RCT. Furthermore, the absence of any mention of case dropout makes the conclusions of this RCT uncertain; a discussion of cases demonstrating difficulty in completing an 8-week psychological program would clarify whether temporary SMT would show efficacy for patients. Finally, it is essential to note that the details of IVF have not been clarified. Since the timing of the SMT and IVF-ET cycles or details of the IVF-ET protocol were not shown, this RCT could not be used as a reference for IVF facilities to actually operate SMT. There is no doubt that psychological interventions are necessary for infertile patients exposed to high psychological stress, but this RCT has many details that have not been clarified, and the conclusions are attenuated. As details become clearer, this RCT will provide a foundation for the active use of SMT in infertility treatment settings.
Koumparou et al.1最近发表了一项随机对照试验(RCT),研究心理干预(压力管理训练,SMT)对计划体外受精(IVF)的妇女的有效性。他们得出结论,尽管SMT对试管婴儿结果的影响有限,但它显著降低了不孕患者的压力水平。由于大多数接受不孕症治疗的妇女都暴露在高心理压力下,2本研究可能在证明需要积极的SMT来维持不孕症妇女的心理健康和继续治疗的动力方面具有重要价值。然而,我们担心这项随机对照试验的可靠性在几个方面受到了损害。首先,RCT的注册没有明确规定。根据联合试验报告标准(CONSORT) 2010指南,RCT的前瞻性注册是必需的,这可以防止对结果选择偏差的不必要的担忧。3,4其次,缺乏病例和对照组参与者背景的具体数据可能会扭曲RCT结果。文章指出,两组之间没有显著差异。然而,由于老龄化和长期的不孕症治疗增加了不孕症患者的心理负担,因此需要详细的背景信息才能准确地解释一项RCT的结果。无法确定选择偏倚,这削弱了该RCT的有效性。此外,没有提及病例退出,使得该RCT的结论不确定;对难以完成8周心理治疗项目的病例进行讨论,将阐明临时SMT是否对患者有效。最后,必须指出的是,试管婴儿的细节尚未澄清。由于没有显示SMT和IVF- et周期的时间或IVF- et方案的细节,因此该随机对照试验不能作为IVF机构实际操作SMT的参考。毫无疑问,心理干预对于暴露于高心理压力下的不孕症患者是必要的,但本RCT有许多细节没有得到澄清,结论有所弱化。随着细节变得更加清晰,这项随机对照试验将为在不孕症治疗环境中积极使用SMT提供基础。
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引用次数: 0
Cognitive changes in health locus of control attributions after behavioral analysis in patients with panic disorder and/or agoraphobia. 惊恐障碍和/或广场恐怖症患者行为分析后健康控制源归因的认知变化
Q3 Medicine Pub Date : 2022-04-27 DOI: 10.22365/jpsych.2022.075
Y. Kasvikis, T. Mitsopoulou, E. Alexiou
Patients with Panic Disorder and / or Agoraphobia (PD +/- Ag) attribute their mental health more to external factors and less to internal, while after behavior treatment (BT) their external attributions decrease and internal attributions increase. We examined whether these cognitive changes observed at the end of BT, begin earlier. Forty patients with PD +/- Ag were assessed on the Multidimensional Health Locus of Control Scale, before and after the diagnostic and psychoeducational sessions that precede the clinical implementation of BT. Decreased health attributions to significant others (t = 4.22, p < 0.01), and an increase trend to self (t = -0.78, p = 0.43) were observed, which are compatible with the active role patients need to adopt in the clinical application of BT.
惊恐障碍和/或广场恐怖症(PD +/- Ag)患者的心理健康多归因于外部因素,少归因于内部因素,而行为治疗(BT)后其外部归因减少,内部归因增加。我们检查了在BT结束时观察到的这些认知变化是否开始得更早。对40例PD +/- Ag患者在临床实施BT前进行诊断和心理教育前后的多维健康控制源量表进行评估,发现对显著他人的健康归因减少(t = 4.22, p < 0.01),对自我的健康归因增加(t = -0.78, p = 0.43),这与患者在临床应用BT时需要采取的积极作用相一致。
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引用次数: 0
Modern bioethical issues: Euthanasia, physician assisted suicide and abortion. Comparative study of attitudes between physicians and law professionals. 现代生物伦理问题:安乐死,医生协助自杀和堕胎。医师与法律专业人员态度的比较研究。
Q3 Medicine Pub Date : 2022-03-28 Epub Date: 2021-11-26 DOI: 10.22365/jpsych.2021.043
Nafsika Malikentzou, Athanasios Douzenis, Fotios Chatzinikolaou, Panagiota Bali, Ioannis Michopoulos

We aimed to examine and compare the attitudes of physicians and law professionals on modern bioethical issues. Euthanasia, physician assisted suicide and abortion were selected for this study, as they underline the conflict between human life as a fundamental value, and the individual's right to self-determination. The demand of euthanasia and physician assisted suicide services reflects each person's right to decide on the way their life will end, while the legalization of abortion determines the individual's right to self-determination. These are complex issues with moral, religious and social implications, and as such tend to divide public opinion. In order to investigate their attitudes, physicians of all specialties, as well as law professionals from all over Greece, were invited to participate in the study. In total, 220 professionals responded to the call and participated in the survey. The professionals involved showed fairly high rates of agreement in all the issues studied, but a significant difference in results was found when the occupation of participants was set as a criterion, with physicians being more negative to euthanasia, physician assisted suicide and abortion than lawyers. Religiousness, age and male sex were negatively correlated with "positive" attitudes towards euthanasia, physician assisted suicide and abortion. Moreover, participants' attitudes towards euthanasia and physician assisted suicide were found to predict their attitudes towards abortion, indicating a single ideological direction of agreement or disagreement, accordingly. Individuals' attitudes and opinions are complicated issues, not easy to be categorized. However, it is of scientific interest to shape a legislative framework that is close to the social consensus, ideological evolution and moral needs. This study tried to pave the way for a modern approach to the issues of euthanasia, physician assisted suicide and abortion.

我们的目的是检查和比较医生和法律专业人士对现代生物伦理问题的态度。本研究选择安乐死、医生协助自杀和堕胎,因为它们强调了作为基本价值的人类生命与个人自决权利之间的冲突。安乐死和医生协助自杀服务的需求反映了每个人决定自己生命结束方式的权利,而堕胎的合法化决定了个人的自决权。这些都是涉及道德、宗教和社会的复杂问题,因此往往导致公众意见分歧。为了调查他们的态度,所有专业的医生以及来自希腊各地的法律专业人士都被邀请参加了这项研究。总共有220名专业人士响应并参与了调查。参与调查的专业人员在所有问题上都表现出相当高的认同率,但当参与者的职业被设定为标准时,结果发现了显著的差异,医生对安乐死、医生协助自杀和堕胎的态度比律师更消极。宗教信仰、年龄和男性对安乐死、医生协助自杀和堕胎的“积极”态度呈负相关。此外,研究发现,参与者对安乐死和医生协助自杀的态度可以预测他们对堕胎的态度,从而显示出一个单一的思想方向,即同意或不同意。个人的态度和意见是复杂的问题,不容易归类。然而,塑造一个接近社会共识、意识形态演变和道德需要的立法框架具有科学意义。这项研究试图为安乐死、医生协助自杀和堕胎等问题的现代方法铺平道路。
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引用次数: 2
The effects of parental divorce on children. 父母离婚对孩子的影响。
Q3 Medicine Pub Date : 2022-03-28 Epub Date: 2021-11-26 DOI: 10.22365/jpsych.2021.040
Hüseyin Çaksen

Family is very important for development of children. Divorce is a life event with a high level of stress for the entire family. Children are dependent on parents and disadvantaged during divorce because it is out of their control.1 Herein, we present our observations about children whose parents separated or divorced to increase the awareness of physicians about the negative effects of divorce. Individuals affected by parental divorce have a higher risk of developing a variety of mental health conditions including emotional and behavioral disorders, poor school performance, depression, anxiety, suicidal ideation, suicide attempt, distress, smoking and substance abuse.2,3 Externalizing problems in girls precede and predict later parental divorce. Post-divorce problems in children vary by raters, and may depend on the time lapse since divorce.4 Lansford et al 5 noted that early parental divorce/separation is more negatively related to trajectories of internalizing and externalizing problems than is later divorce/separation, whereas later divorce/separation is more negatively related to grades. In another study, divorce in parents was significantly associated with higher alcohol use disorder, higher cigarette dependence and higher water pipe dependence in adolescents.6 In the study of Tullius et al 7 the levels of both internalizing and externalizing problems were significantly higher in the period after parental divorce, but not in the period before divorce, with a persistent and increasing effect over the follow-up periods compared to adolescents not experiencing divorce. Zeratsion et al 8 reported that parental divorce in late adolescence does not lead to mental health problems, as has been shown before, while such problems may prevail among young adolescents. This does not mean that parental divorce creates less problems in late adolescence than before but these youths might have developed adjustment abilities against health effects as divorce have turned to be more common. In our clinical practice, we have also observed various emotional, behavioral, psychosomatic, and conversion disorders in children, particularly in preadolescents and adolescents, before and/or after a separation or divorce of parents. Children often lack information and skills to overcome the challenges that the divorce carries. Conflicting relationships between parents make up the biggest obstacle that makes it difficult for a child to successfully deal with changes in the family. Even though parents deal with heavy feelings, it is desirable to put them the child and his interests in the first place. In order to stabilize the family system, 2 to 4 years are usually needed.1 Physicians can assist families by providing support and advice, and advocating for children within systems that serve separating families. Physicians can provide information so that individuals who work with such children recognize, and are sensitive to, their individual needs, and provide support

家庭对孩子的成长很重要。离婚对整个家庭来说是一件压力很大的生活事件。孩子依赖父母,在离婚期间处于不利地位,因为他们无法控制在此,我们提出我们的观察关于孩子的父母分居或离婚,以提高医生对离婚的负面影响的认识。受父母离婚影响的个人患各种心理健康状况的风险更高,包括情绪和行为障碍、学习成绩差、抑郁、焦虑、自杀意念、自杀未遂、痛苦、吸烟和滥用药物。2,3女孩的外化问题早于并预示着后来父母的离婚。离婚后孩子的问题因评分者而异,而且可能取决于离婚后的时间Lansford等人5指出,父母早期离婚/分居与内在化和外在化问题轨迹的负相关程度高于后来离婚/分居,而后来离婚/分居与成绩的负相关程度更高。在另一项研究中,父母离婚与青少年较高的酒精使用障碍、较高的香烟依赖和较高的水管依赖显著相关在Tullius等人的研究中,在父母离婚后的一段时间内,内化和外化问题的水平都明显更高,但在离婚前的一段时间内却没有,与没有经历过离婚的青少年相比,在后续的时间里,内化和外化问题的影响持续不断地增加。Zeratsion等8报告说,父母在青春期后期离婚并不会像以前所显示的那样导致精神健康问题,而这类问题可能在青少年中普遍存在。这并不意味着父母离婚在青春期后期产生的问题比以前少,但随着离婚变得越来越普遍,这些年轻人可能已经发展了适应健康影响的能力。在我们的临床实践中,我们也观察到儿童的各种情绪、行为、身心和转换障碍,特别是在青春期前和青少年,在父母分居或离婚之前和/或之后。孩子们往往缺乏信息和技能来克服离婚带来的挑战。父母之间矛盾的关系是孩子难以成功应对家庭变化的最大障碍。即使父母处理沉重的感情,最好把他们的孩子和他的利益放在第一位。为了稳定家庭制度,通常需要2到4年的时间医生可以通过提供支持和建议来帮助家庭,并在为分离家庭服务的系统中倡导儿童。医生可以提供信息,使与这些儿童一起工作的人认识到他们的个人需求,并对他们的个人需求敏感,并在学校、营地和体育活动中为儿童提供支持和培养经验。这些努力将促进受父母分居影响的儿童获得更好的心理健康结果尽量减少分居和离婚对孩子的情感伤害的最重要的方法是确保孩子与父母双方保持亲密和安全的关系,除非有配偶或孩子虐待或忽视,或父母滥用药物为孩子提供适龄的解释和咨询,为父母提供建议和指导,以及推荐阅读材料,可能有助于减少离婚的潜在负面影响。通常,向那些在分离及其后果的社会、情感和法律方面具有专业知识的专业人士咨询可能会对这些家庭有所帮助父母阅读材料中的一个段落的例子如下:人的世俗生活的最全面的中心,它的主要源泉,天堂,避难所和世俗幸福的堡垒,是家庭生活。每个人的家对他/她来说都是一个小世界。通过真诚、认真、忠诚的尊重和真实、温柔、自我牺牲的同情,他/她的家庭和家庭的生活和幸福是可能的。这种真正的尊重和真诚的善良可以通过家庭成员拥有永恒的陪伴、友谊和团聚的观念来实现,他们的父母、子女、兄弟和友好的关系在无限的生命中永远持续下去,并且他们相信这一点最后,我们要强调的是,父母离婚的儿童可能会出现各种社会心理、身心和转化障碍。对儿童健康感兴趣的医生可以在评估儿童时注意到父母的分离问题。转介给具有分离专业知识的专业人士可能对冲突的父母有所帮助。
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引用次数: 1
Substance use during the COVID-19 pandemic: What is really happening? COVID-19大流行期间的物质使用:到底发生了什么?
Q3 Medicine Pub Date : 2022-02-21 DOI: 10.22365/jpsych.2022.072
E. Mellos, T. Paparrigopoulos
The COVID-19 pandemic is associated with increased levels of anxiety, fear, sadness, difficulty adjusting, symptoms of post-traumatic stress disorder and suicidality, both in the general population and specific subgroups. The presence of this type of psychopathology increases the risk of involvement with or worsens the use of addictive substances and alcohol as a maladaptive coping strategy.1 According to these data, people with substance use disorders are a population at high risk for COVID-19 infection and serious illness. Α large controlled retrospective case study in the US found that people with substance use disorders are significantly more vulnerable to COVID-19 and its complications (primarily those with opioid use disorder OR = 10.21 and with tobacco use disorder OR = 8.25), and that the course and outcome of the disease (hospitalization, death) was worse than in non-dependent individuals. The main culprits are increased physical co-morbidity (frequent respiratory and cardiovascular problems), poor health and living conditions, marginalization and difficulties in accessing health services. 2,3 Ιnternational epidemiological data during the first months of the pandemic regarding the use of addictive substances do not lead to safe conclusions. A cross-sectional online epidemiological study conducted on a sample of 36,538 adults from 21 European countries between April and July 2020 found an overall decrease in alcohol use, which was mainly attributed to the reduction of heavy episodic consumption, while at the same time an increase in alcohol consumption among people with severe alcohol use was recorded. Τhe use of cannabis and nicotine showed increasing trends, as well as the use of cocaine, but to a lesser extent, while the use of MDMA (ecstasy) showed a decrease.4 In a review of 45 cross-sectional studies conducted between December 2019 and November 2020, alcohol use was on the rise overall, despite geographical variations, as was the use of other addictive substances, cannabis in particular.5 It should be noted that those who increased alcohol use during quarantine were those exhibiting higher levels of negative emotionality mechanisms.6 In Greece, an online cross-sectional survey in April 2020 in the general population during the first lockdown showed a reduction in alcohol use (43.7% of alcohol users reduced or quit), a reduction in cannabis (67.3% quit), while 33.3% increased nicotine use. These changes were attributed to the limitation of alcohol availability, social distancing, changes in daily routine and income reduction.7,8 Also, wastewater samples from Athens, analyzed by the Laboratory of Analytical Chemistry of EKPA, showed a significant increase in the use of cocaine (67%), amphetamine (350%) and methamphetamine (37%), and a decrease in the use of MDMA (- 38%) during the first lockdown, compared to the corresponding period of the previous year.9 Analysis of wastewater samples from other European cities "suggest that levels o
此外,“调查数据表明,那些在COVID-19之前偶尔使用药物的人可能在大流行期间减少甚至停止使用药物,但更经常使用药物的人可能增加了药物消费量”为控制这一流行病而采取的措施减少和修改了所提供的精神健康和成瘾治疗服务。虽然服务已经充分恢复,但在欧洲,最初提供的解毒服务减少了60%。13主要是团体一级的现场接触大大减少或在很长一段时间内完全停止,个人预约的频率也减少了。治疗方案试图利用技术和远程医疗来应对新的情况,提供在线团体支持和心理治疗。替代治疗方案变得更加灵活,提供长期的药物替代品(带回家),以防止使用者移动。治疗医生在开处方方面也有所便利。因此,成瘾者与治疗过程保持联系,但不足以满足他们在此期间增加的需求。最后,应当指出,药物使用似乎与流行病及其造成的精神病理有一种自主的动态关系,与流行病有一种"松散的"因果关系。因此,应避免草率和不合时宜的概括,不应通过以往不同类型的社会经济危机的外推或通过片面的时空理解来轻易得出结论,这通常是媒体以负面警示信息的形式呈现的。
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引用次数: 15
Exhaustion and burnout in the healthcare system in Greece: A cross-sectional study among internists during the COVID-19 lockdown. 希腊医疗保健系统的疲劳和倦怠:COVID-19封锁期间内科医生的横断面研究。
Q3 Medicine Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.067
E. Karlafti, Emmanouil S. Benioudakis, E. Barouxi, G. Kaiafa, T. Didangelos, K. Fountoulakis, S. Pagoni, C. Savopoulos
The COVID-19 pandemic has rapidly changed everyday life around the world. The situation created by the COVID-19 pandemic has been shown to be associated with severe mental health problems in frontline medical and nursing staff. The aim of this study was to investigate exhaustion, disengagement, secondary traumatic stress, compassion satisfaction, burnout, as well as depression, anxiety and stress among internists in Greece, during the second lockdown period. Internists were approached through the Internal Medicine Society of Greece and a total of 117 participated in the study (response rate: 15.3%). The participants responded through a Google form on the Depression, Anxiety and Stress Scale - 21, the Oldenburg Burnout Inventory (OLBI) and the Professional Quality of Life Scale version 5 (ProQOL-5). Exhaustion was found in the majority of the participants (88%), 65.8% met the criteria for at least moderate levels of compassion satisfaction and 71.8% presented moderate levels of burnout. Furthermore, about half of the participants met the criteria for moderate to extremely severe levels of depression, anxiety and stress. Finally, regression analyses showed that depression was associated with both the OLBI and ProQOL-5 scales. The majority of the internists, during the lockdown period in Greece, were evaluated as "exhausted", with high rates of negative psychological symptoms. The present study, despite the limitations, highlights the impact of the COVID-19 pandemic on internists, which triggered a shift in attention onto the treatment, and especially the prevention, of stressful situations for health professionals.
COVID-19大流行迅速改变了世界各地的日常生活。新冠肺炎大流行造成的局势已被证明与一线医护人员严重的心理健康问题有关。本研究的目的是调查希腊内科医生在第二次封锁期间的疲劳、脱离、继发性创伤压力、同情满意度、倦怠以及抑郁、焦虑和压力。通过希腊内科医学会(Internal Medicine Society of Greece)联系内科医生,共有117人参与了这项研究(回复率:15.3%)。参与者通过抑郁、焦虑和压力量表- 21、Oldenburg倦怠量表(OLBI)和职业生活质量量表第5版(ProQOL-5)的谷歌表进行回应。大多数参与者(88%)感到疲惫,65.8%的人满足至少中等程度的同情满意度标准,71.8%的人表现出中等程度的倦怠。此外,大约一半的参与者符合中度到极严重程度的抑郁、焦虑和压力的标准。最后,回归分析显示抑郁与OLBI和ProQOL-5量表均相关。在希腊封锁期间,大多数内科医生被评估为“疲惫不堪”,出现负面心理症状的比例很高。尽管存在局限性,但本研究强调了COVID-19大流行对内科医生的影响,这引发了对卫生专业人员压力情况的治疗,特别是预防的注意力转移。
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引用次数: 5
Association of cognitive function of non-demented elderly primary care attendees with physical, mental, and sociodemographic factors. 非痴呆老年初级保健参与者的认知功能与身体、精神和社会人口因素的关联。
Q3 Medicine Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.069
Aglaia Roganaki, T. Vorvolakos, Elpida Sokou, G. Tripsianis, Theodoros Konstadinidis, M. Samakouri
Preservation of a population's cognitive functions is a matter of increased concern for all healthcare systems. The detection of factors that are associated with cognitive functions is a matter of increased interest to both the treatment of vulnerable individuals and the implementation of strategies to delay age-related cognitive decline. This study aimed to highlight sociodemographic, physical, and mental health factors associated with the cognitive function in non-demented elderly primary health care attendees. The sample consisted of 362 primary health care attendees aged 60 years or above. A questionnaire regarding sociodemographic and physical health history, along with a battery of psychometric instruments consisting of the Test Your Memory (TYM) test, Geriatric Depression Scale-Short Form (GDS-15), Short Anxiety Screening Test (SAST), and World Health Organization-Five Well-Being Index (WHO-5), were given to all participants.Participants who scored below 39/40 in the TYM, which is the cut-off point for dementia screening in the version of the test we used, were excluded from further assessment. For the rest of the participants, 267 in total, their TYM scores were significantly and negatively correlated with age and SAST scores. Participants with lung and vascular health history problems scored lower in the TYM, as did those with poor education, who lived alone, and who lived in Alexandroupolis. Finally, healthy participants scored higher than individuals with at least one medical condition. Linear multiple regression analysis revealed a model (adjusted R2 = 25.80, F = 10.11, p < 0.001) with three factors (age (beta = -0.32), lung problems (beta = -0.23), and vascular factors (beta = -0.20) that could significantly predict 25.80% of the variance in TYM scores. Preservation of physical health, especially lung and vascular health, along with anxiety alleviation help to counterbalance the negative effect of aging on cognitive function in non-demented elderly primary care attendees.
保护人群的认知功能是所有医疗保健系统日益关注的问题。检测与认知功能相关的因素对于治疗脆弱个体和实施延迟与年龄相关的认知衰退的策略都是一个越来越重要的问题。本研究旨在强调社会人口学、生理和心理健康因素与非痴呆老年人初级卫生保健参与者的认知功能相关。样本包括362名60岁或以上的初级卫生保健参加者。向所有参与者发放了一份关于社会人口统计和身体健康史的问卷,以及一系列心理测量工具,包括测试你的记忆(TYM)测试、老年抑郁量表-短表(GDS-15)、短焦虑筛查测试(SAST)和世界卫生组织五幸福指数(WHO-5)。在我们使用的测试版本中,TYM得分低于39/40的参与者被排除在进一步的评估之外。TYM是痴呆症筛查的分界点。对于其余的267名参与者,他们的TYM分数与年龄和SAST分数呈显著负相关。有肺部和血管健康史问题的参与者在TYM中的得分较低,受教育程度低、独居和住在亚历山德鲁波利斯的人也是如此。最后,健康的参与者比至少有一种疾病的人得分更高。线性多元回归分析显示,年龄(β = -0.32)、肺部问题(β = -0.23)和血管因素(β = -0.20)三个因素的模型(调整后R2 = 25.80, F = 10.11, p < 0.001)可以显著预测25.80%的TYM评分方差。保持身体健康,特别是肺和血管健康,以及缓解焦虑有助于抵消衰老对非痴呆老年初级保健参与者认知功能的负面影响。
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引用次数: 0
Effectiveness of a hybrid arts-based Cognitive Behavioral Therapy intervention for patients with non-malignant chronic pain. 基于艺术的混合认知行为疗法对非恶性慢性疼痛患者的干预效果。
Q3 Medicine Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.064
Asimina Kalmanti, C. Batistaki, C. Christodoulou, Georgia Gerolouka-Kostopanagiotou, A. Douzenis, I. Michopoulos
Chronic Pain (CP) is defined as pain that persists or recurs for more than 3 to 6 months and may be conceived as a health condition in its own right. CP is a frequent condition, affecting an estimated 20% of people worldwide and requires special treatment and care. CP can contribute to depression, anxiety, sleep disturbances, poor quality of life and increased health care costs. Psychosocial approaches based on a cognitive conceptualization of pain can provide a solid foundation for research and clinical work. The development of a 10 week-session group treatment was based on key principles from the literature on Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) and Creative Arts Therapy, integrated with advances in research on CP management framework. The aim of this study is to evaluate a CBT-CP arts-based group intervention for patients with non-malignant CP addressing the biopsychosocial factors that influence pain perception. A total of 100 University Pain Management Unit outpatients participated, 50 in the intervention group and 50 in the control group (treatment as usual). In analyses of the pretest-posttest research design intervention including all participants, treatment gains were observed in almost all domains examined: severity of pain measured by the Brief Pain Inventory, conceptualization of mental pain measured by the Orbach and Mikulincer Mental Pain Scale, tolerance for psychological pain measured by the Tolerance for Mental Pain Scale, anxiety and depression levels measured by the Hospital Anxiety and Depression Scale, and quality of life measured by the WHO Quality of Life-BREF Questionnaire. The participants' mean age was 52.3 years and most were female (84%). Findings suggest that postprogram, there was significant reduction in pain intensity (p<0.001), depressive symptoms (p<0.001), confusion about pain (p=0.037), and improvement of emotional distress tolerance (p=0.012) and global health-related quality of life (p<0.001) in the intervention group. Beneficial effects can be expected from the implementation of an integrated CP intervention (including: creative and CBT techniques) reappraising some of the coping responses defined as adaptive within current psychosocial non-malignant CP regimens.
慢性疼痛(CP)被定义为持续或复发超过3至6个月的疼痛,可被视为一种健康状况。CP是一种常见病,影响全世界约20%的人,需要特殊治疗和护理。CP会导致抑郁、焦虑、睡眠障碍、生活质量差和医疗费用增加。基于疼痛认知概念化的社会心理方法可以为研究和临床工作提供坚实的基础。基于慢性疼痛认知行为治疗(CBT-CP)和创造性艺术治疗文献的关键原则,结合慢性疼痛管理框架的研究进展,开发了为期10周的小组治疗。本研究的目的是评估基于CBT-CP艺术的非恶性CP患者群体干预,解决影响疼痛感知的生物心理社会因素。共有100名大学疼痛管理科门诊患者参与,干预组50名,对照组50名(照常治疗)。在包括所有参与者的前测后测研究设计干预的分析中,几乎在所有检查的领域都观察到治疗收益:通过简短疼痛量表测量疼痛的严重程度,通过Orbach和Mikulincer心理疼痛量表测量精神疼痛的概念化,通过心理疼痛耐受性量表测量心理疼痛的耐受性,通过医院焦虑和抑郁量表测量焦虑和抑郁水平,以及通过世卫组织生活质量问卷测量生活质量。参与者的平均年龄为52.3岁,大多数是女性(84%)。研究结果显示,干预组患者的疼痛强度(p<0.001)、抑郁症状(p<0.001)、疼痛困惑(p=0.037)、情绪困扰耐受性(p=0.012)和总体健康相关生活质量(p<0.001)显著降低。实施综合CP干预(包括:创造性和CBT技术)可以预期有益的效果,重新评估当前社会心理非恶性CP方案中定义为适应性的一些应对反应。
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引用次数: 0
Psychopharmacology of patients with multiple sclerosis in Greece during the period 2017-2019. 2017-2019年希腊多发性硬化患者的精神药理学研究
Q3 Medicine Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.057
C. Bakirtzis, M. Karakasi, M. Boziki, T. Moysiadis, Dimitra Tsakona, B. Fyntanidou, G. Papazisis, E. Thireos, N. Grigoriadis
Multiple Sclerosis (MS) is highly comorbid with mental disorders in any disease stage, while psychiatric manifestations may precede the onset of neurological symptoms as well as diagnosis. Neuropsychiatric comorbidities are associated with an elevated risk of MS disability progression, and therefore, people with multiple sclerosis (PwMS) with psychiatric comorbidities often experience a significantly lower functional status, perform worse in objective neuropsychological assessment, are less likely to adhere to pharmacological treatment, and exhibit higher levels of disruption of their supportive social environment as compared with "non-psychiatric" PwMS. The present study aims to estimate the nationwide use of psychopharmacological agents by PwMS in Greece. Prescription records of the nationwide digital prescription database were analyzed, in order to identify PwMS that have received prescriptions of an antipsychotic, an antidepressant, an anxiolytic or a psychostimulant during a 2-year study period. Pseudo-anonymized prescription records of PwMS (n=21218) were extracted from the Greek nationwide prescription database, dating from June 2017 to May 2019. According to this national level study, psychopharmacological agents are frequently prescribed in PwMS. Antidepressants were prescribed in 36.1% of the study sample, followed by anxiolytics (16.23%), psychostimulants (4.97%) and antipsychotics (3.76%). The proportion of patients under treatment with these agents was increasing with age. Selective serotonin reuptake inhibitors, second generation antipsychotics and benzodiazepines were the most often prescribed agents in each drug category and especially in younger age groups, possibly indicating a better efficacy/side-effect equilibrium, while modafinil was the only psychostimulant prescribed aiming to ameliorate levels of fatigue. A pharmacological preference for antidepressants and psychostimulants was observed in the 40-60 age group (p = 0.02), while antipsychotics and anxiolytics were more frequently prescribed in the >60 age group (p<0.001). Serotonin-norepinephrine reuptake inhibitors were mostly prescribed within the 40-60 age-group. Benzodiazepines were less favored among the >60 age-group. This study highlights the increased prevalence of mental disorders in this patient group. Adequate treatment and monitoring of psychiatric symptomatology, may improve long-term outcomes of the disease, however caution is needed regarding potential drug interactions and side effects.
多发性硬化症(MS)在任何疾病阶段都与精神障碍高度合并症,而精神病学表现可能先于神经症状的发作以及诊断。神经精神合并症与多发性硬化症残疾进展的风险升高有关,因此,与“非精神”多发性硬化症相比,伴有精神疾病合并症的多发性硬化症(PwMS)患者往往经历明显较低的功能状态,在客观神经心理学评估中表现较差,不太可能坚持药物治疗,并且表现出更高程度的支持性社会环境的破坏。本研究旨在估计希腊PwMS在全国范围内使用精神药理学药物的情况。分析全国数字处方数据库的处方记录,以确定在2年的研究期间接受过抗精神病药、抗抑郁药、抗焦虑药或精神兴奋剂处方的PwMS。从希腊全国处方数据库中提取PwMS的伪匿名处方记录(n=21218),时间为2017年6月至2019年5月。根据这项全国性的研究,精神药理学药物经常被用于精神病治疗。服用抗抑郁药的占36.1%,其次是抗焦虑药(16.23%)、精神兴奋剂(4.97%)和抗精神病药(3.76%)。接受这些药物治疗的患者比例随着年龄的增长而增加。选择性血清素再摄取抑制剂、第二代抗精神病药物和苯二氮卓类药物是每个药物类别中最常用的处方药物,尤其是在年轻人群中,可能表明更好的疗效/副作用平衡,而莫达非尼是唯一用于改善疲劳水平的精神兴奋剂。40 ~ 60岁年龄组更倾向于使用抗抑郁药和精神兴奋剂(p = 0.02),而60 ~ 60岁年龄组更倾向于使用抗精神病药和抗焦虑药(p = 60)。这项研究强调了这一患者群体中精神障碍患病率的增加。适当的治疗和精神症状监测可能改善疾病的长期预后,但需要注意潜在的药物相互作用和副作用。
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引用次数: 0
Obsessive-compulsive symptoms in pregnancy: Their relationship with obsessive beliefs and obsessive-compulsive personality traits. 怀孕期间的强迫症状:与强迫信念和强迫人格特征的关系。
Q3 Medicine Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.071
Ekaterini Vasileiou, Panagiota Fexi, A. Spyropoulou, I. Mourikis, Theodoros Chalimourdas, I. Zervas
Literature findings are limited and inconsistent on the relationship between obsessive beliefs and obsessive-compulsive symptoms (OCS) and to our knowledge no data are available in pregnant population. Additionally, an interesting field that has not been adequately studied is the relationship between obsessive-compulsive personality traits and OCS while there are no corresponding studies in perinatal period. The aims of the study were to examine the relationship between OCS presented in pregnancy and obsessive beliefs considered to underlie them as well as their association with obsessive-compulsive personality traits. 30 pregnant women with OCS, regardless of their underlying diagnosis, were recruited from a University Psychiatric Hospital and privately. They completed the Mini International Neuropsychiatric Interview (MINI), the Yale-Brown Obsessive- Compulsive Scale (Y-BOCS), the Dysfunctional Beliefs Questionnaire-44 (OBQ-44), the Leyton Trait Scale and the Hospital Anxiety and Depression Scale (HADS). The main symptoms were aggression (73.3%), contamination (53.3%) obsessions and cleansing/washing (50%), checking (43.3%) compulsions. Pregnant women with obsessive-compulsive personality traits displayed symmetry/exactness obsessions (p=0.020) and cleansing/washing (p=0.011) compulsions as predominant types of OCS and greater severity of compulsions (p=0.049). The results of the logistic regression model suggest that obsessive beliefs of importance/control of thoughts and of responsibility/threat estimation predicted OCS while the belief of perfectionism/certainty did not predict any dimension of OCS. It is noteworthy that most observed relationships between obsessive beliefs and OCS remained even after controlling for variables of anxiety and depression, suggesting that obsessive beliefs have a specific relationship with OCS which is independent of other forms of psychopathology. Depressive symptoms comorbidity increased OCS severity, while in comorbidity with anxiety symptoms no difference in severity of OCS was found. Further research is needed to test our findings in larger and more diverse samples.
关于强迫信念与强迫症(OCS)之间关系的文献发现有限且不一致,据我们所知,没有怀孕人群的数据。此外,强迫性人格特征与强迫症之间的关系是一个尚未得到充分研究的有趣领域,而在围产期没有相应的研究。这项研究的目的是研究怀孕期间出现的强迫症与强迫症背后的强迫信念之间的关系,以及强迫症与强迫症人格特征之间的关系。从大学精神病院私下招募了30名患有OCS的孕妇,无论她们的潜在诊断如何。他们完成了迷你国际神经精神病学访谈(Mini)、耶鲁-布朗强迫症量表(Y-BOCS)、功能失调信念问卷-44 (OBQ-44)、莱顿特质量表和医院焦虑抑郁量表(HADS)。主要症状为攻击(73.3%)、污染(53.3%)、强迫和清洁/洗涤(50%)、检查(43.3%)强迫。具有强迫人格特征的孕妇表现出对称/精确强迫症(p=0.020)和清洁/洗涤强迫症(p=0.011)强迫症是强迫症的主要类型,强迫症的严重程度更高(p=0.049)。逻辑回归模型的结果表明,强迫信念的重要性/控制思想和责任/威胁估计预测OCS,而完美主义/确定性的信念没有预测OCS的任何维度。值得注意的是,即使在控制了焦虑和抑郁变量后,大多数观察到的强迫信念与强迫症之间的关系仍然存在,这表明强迫信念与强迫症之间存在一种独立于其他精神病理形式的特定关系。抑郁症状合并症加重了OCS的严重程度,而与焦虑症状合并症的OCS严重程度无差异。我们需要进一步的研究,在更大、更多样化的样本中检验我们的发现。
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