Pub Date : 2023-01-01DOI: 10.5455/rmj.20230518092707
Heyam Kenani, Aqeel Khafaji
Objective: To diagnose H. pylori infection and assess the likelihood of developing gastric cancer. It is necessary to describe instances and phenotypes of necroptosis in gastric cells. Methodology: Fifty patients who had undergone gastrectomy from January 2020 to December 2022 were interviewed. A noninvasive investigation has been performed on each specimen to check for the presence of H. pylori by using stool, antibody test, urea breath test, and biopsy taken on endoscopy. Results: Increased population of RIPK3-positive cells was observed in both gastric glands and lamina propria in H. pylori infected human oxyntic gastritis and atrophic specimens. Phenotypic analysis revealed that many RIPK3-positive cells were H + K+ ATPase-positive parietal cells in the gastric glands and are predominantly CD3-positive T lymphocytes CD68-positive macrophages, and SMA-alpha-positive stromal cells. Positive tests for H. pylori were conducted on 50 individuals on chemotherapy who already had gastric cancer as a consequence of exposure to bacteria. The incidence of stomach cancer was 62% in males and 38% in females with age between 30-85 years. Conclusion: An increased population of RIPK3-positive cells was observed in several types of gastric cells. Future studies that define the effects and mechanisms developed of H. pylori disorders are needed.
{"title":"Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq","authors":"Heyam Kenani, Aqeel Khafaji","doi":"10.5455/rmj.20230518092707","DOIUrl":"https://doi.org/10.5455/rmj.20230518092707","url":null,"abstract":"Objective: To diagnose H. pylori infection and assess the likelihood of developing gastric cancer. It is necessary to describe instances and phenotypes of necroptosis in gastric cells. Methodology: Fifty patients who had undergone gastrectomy from January 2020 to December 2022 were interviewed. A noninvasive investigation has been performed on each specimen to check for the presence of H. pylori by using stool, antibody test, urea breath test, and biopsy taken on endoscopy. Results: Increased population of RIPK3-positive cells was observed in both gastric glands and lamina propria in H. pylori infected human oxyntic gastritis and atrophic specimens. Phenotypic analysis revealed that many RIPK3-positive cells were H + K+ ATPase-positive parietal cells in the gastric glands and are predominantly CD3-positive T lymphocytes CD68-positive macrophages, and SMA-alpha-positive stromal cells. Positive tests for H. pylori were conducted on 50 individuals on chemotherapy who already had gastric cancer as a consequence of exposure to bacteria. The incidence of stomach cancer was 62% in males and 38% in females with age between 30-85 years. Conclusion: An increased population of RIPK3-positive cells was observed in several types of gastric cells. Future studies that define the effects and mechanisms developed of H. pylori disorders are needed.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135358942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230227075331
Mohammed Junaid, Rakan Almutairi, Turki Alqahtani, Mohammed Alsalem, Mohammed Alrashidi, Sultan Alsaadoon
Objectives: To investigate the impact of COVID-19 pandemic on physical activity and academic performance among students of Majmaah University, KSA. Methodology: This descriptive cross-sectional study included 200 all year’s medical students of either gender of Majmaah University. Complete enumeration technique was used for data collection. An online google form was shared with the study participants. Data were analyzed using SPSS version 24. The study was completed in six months. Results: Students with higher grades spent most of their time sitting without engaging in mild to moderate or severe physical activity. We found that 43 (21.5%) participants gained 1-5kg, 42 (21%) 5-10kg, 14 (7%) gained more than 10kg. On the other hand, 38 (19%) participants lost 1-5kg, 30 (15%) lost 5-10kg, 18 (9%) lost more than 10kg and 114 (57%) of the participants had no change in weight during the corona pandemic. Conclusion: Regardless of the COVID-19 pandemic, physical inactivity is considered as a separate pandemic. Students' capacity to engage in sufficient amounts of physical activity to preserve health and avoid disease may have been hampered by the COVID-19 pandemic.
目的:了解2019冠状病毒病(COVID-19)大流行对沙特Majmaah大学学生体育活动和学习成绩的影响。方法:这项描述性横断面研究包括200名全年在Majmaah大学就读的男女医科学生。数据采集采用完全枚举技术。研究人员与参与者分享了一份在线谷歌表格。数据采用SPSS version 24进行分析。这项研究在六个月内完成。结果:成绩较高的学生大部分时间都坐着，没有进行轻度到中度或重度的体育活动。我们发现43名(21.5%)参与者体重增加1-5kg, 42名(21%)参与者体重增加5-10kg, 14名(7%)参与者体重增加超过10kg。另一方面，38名(19%)参与者减轻了1-5公斤，30名(15%)减轻了5-10公斤，18名(9%)减轻了10公斤以上，114名(57%)参与者在冠状病毒大流行期间体重没有变化。结论:无论COVID-19大流行如何，缺乏身体活动都被视为单独的大流行。2019冠状病毒病(COVID-19)大流行可能阻碍了学生参与足够数量的身体活动以保持健康和避免疾病的能力。
{"title":"Impact of COVID-19 pandemic on physical activity and academic performance among medical students; A single center study from Saudi Arabia","authors":"Mohammed Junaid, Rakan Almutairi, Turki Alqahtani, Mohammed Alsalem, Mohammed Alrashidi, Sultan Alsaadoon","doi":"10.5455/rmj.20230227075331","DOIUrl":"https://doi.org/10.5455/rmj.20230227075331","url":null,"abstract":"Objectives: To investigate the impact of COVID-19 pandemic on physical activity and academic performance among students of Majmaah University, KSA. Methodology: This descriptive cross-sectional study included 200 all year’s medical students of either gender of Majmaah University. Complete enumeration technique was used for data collection. An online google form was shared with the study participants. Data were analyzed using SPSS version 24. The study was completed in six months. Results: Students with higher grades spent most of their time sitting without engaging in mild to moderate or severe physical activity. We found that 43 (21.5%) participants gained 1-5kg, 42 (21%) 5-10kg, 14 (7%) gained more than 10kg. On the other hand, 38 (19%) participants lost 1-5kg, 30 (15%) lost 5-10kg, 18 (9%) lost more than 10kg and 114 (57%) of the participants had no change in weight during the corona pandemic. Conclusion: Regardless of the COVID-19 pandemic, physical inactivity is considered as a separate pandemic. Students' capacity to engage in sufficient amounts of physical activity to preserve health and avoid disease may have been hampered by the COVID-19 pandemic.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135709641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230523054728
Sri Wardojo, Rakhmad Rosadi, Owen Nkoka, Sun Qianhui, Aqila Cintia, Prasasti Seputri
Objective: To investigate the relationship between depression and activity daily living (ADL) towards balance among knee osteoarthritis patients in Malang. Methodology: This cross-sectional study with purposive sampling technique was conducted in primary healthcare centers in Malang and included 166 participants. Patients aged above 60 years, diagnosed with knee osteoarthritis with Kellgren-Lawrence grade 1-2, had symptoms of depression/mild depression (based on medical diagnosis), did not have severe visual disturbances; did not have neurological problems and did not consume any antidepressants were included in the study. We used Geriatric Depression Scale, Barthel Index, and Single Leg Standing test. All the data were analyzed using the Independent T-test and Pearson Correlation. Results: Depression negatively correlated with balance ability (p<0.05; r1=-0.25). Ability to do daily activities was positively correlated with balance ability (p<0.05; r = 0.55). Conclusion: It is urged to focus on maintaining and promoting knee osteoarthritis patients’ psychological health and recommend it to be included in the policy of geriatric health management. This will minimize the occurrence of potentially harmful secondary effects and gain an optimal quality of life for the elderly.
{"title":"Analysis of depression, activity of daily of living and balance among elderly with knee osteoarthritis in Malang, Indonesia","authors":"Sri Wardojo, Rakhmad Rosadi, Owen Nkoka, Sun Qianhui, Aqila Cintia, Prasasti Seputri","doi":"10.5455/rmj.20230523054728","DOIUrl":"https://doi.org/10.5455/rmj.20230523054728","url":null,"abstract":"Objective: To investigate the relationship between depression and activity daily living (ADL) towards balance among knee osteoarthritis patients in Malang. Methodology: This cross-sectional study with purposive sampling technique was conducted in primary healthcare centers in Malang and included 166 participants. Patients aged above 60 years, diagnosed with knee osteoarthritis with Kellgren-Lawrence grade 1-2, had symptoms of depression/mild depression (based on medical diagnosis), did not have severe visual disturbances; did not have neurological problems and did not consume any antidepressants were included in the study. We used Geriatric Depression Scale, Barthel Index, and Single Leg Standing test. All the data were analyzed using the Independent T-test and Pearson Correlation. Results: Depression negatively correlated with balance ability (p<0.05; r1=-0.25). Ability to do daily activities was positively correlated with balance ability (p<0.05; r = 0.55). Conclusion: It is urged to focus on maintaining and promoting knee osteoarthritis patients’ psychological health and recommend it to be included in the policy of geriatric health management. This will minimize the occurrence of potentially harmful secondary effects and gain an optimal quality of life for the elderly.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135709648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230409073401
Reem Haddad
Objective: To evaluate some biochemical parameters in Iraqi women patients with preeclampsia (PE). Methodology: In this study, data were collected from December 2022 and March 2023 at Department of Obstetrics and Gynecology, Al-Elwiya Maternity Teaching Hospital from 31 pregnant women with PE. We had 31 pregnant women in the control group who were healthy. Age, gestational age, BMI, and renal function tests are performed. Results: There was no difference in age, and gestational age (weeks), between PE women and the control group. Serum total bilirubin, creatinine, and urea levels were all considerably higher in PE than in the control group. There were no statistically significant differences in serum albumin and total protein levels, although the SBP and DBP from PE patients were significantly higher than those of the control group. Conclusion: Pregnant women should be evaluated because elevated serum levels of total bilirubin, creatinine, and urea may signal the onset of preeclampsia. The best biochemical test for diagnosing preeclampsia was serum creatinine level.
{"title":"Evaluation of biochemical parameters in Iraqi women patients with preeclampsia","authors":"Reem Haddad","doi":"10.5455/rmj.20230409073401","DOIUrl":"https://doi.org/10.5455/rmj.20230409073401","url":null,"abstract":"Objective: To evaluate some biochemical parameters in Iraqi women patients with preeclampsia (PE). Methodology: In this study, data were collected from December 2022 and March 2023 at Department of Obstetrics and Gynecology, Al-Elwiya Maternity Teaching Hospital from 31 pregnant women with PE. We had 31 pregnant women in the control group who were healthy. Age, gestational age, BMI, and renal function tests are performed. Results: There was no difference in age, and gestational age (weeks), between PE women and the control group. Serum total bilirubin, creatinine, and urea levels were all considerably higher in PE than in the control group. There were no statistically significant differences in serum albumin and total protein levels, although the SBP and DBP from PE patients were significantly higher than those of the control group. Conclusion: Pregnant women should be evaluated because elevated serum levels of total bilirubin, creatinine, and urea may signal the onset of preeclampsia. The best biochemical test for diagnosing preeclampsia was serum creatinine level.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135709650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230106050554
Ghaida R. Hamid
Objective: To explore the KAP of medical students in Baghdad city towards COVID-19, during the year 2022. Methodology: This cross-sectional study was carried out from April to June 2022 and included 2000 medical students from four medical schools in Baghdad. A systematic random sampling technique was used and every second student was included from four colleges with 4000 students in all four colleges. Thus, 2000 students were included and a self-structured questionnaire was used. Results: Complete esponses were received from 1738 students. Most were aged 20 to 22 years, approximately equally distributed as males and females. About 46.49% of the students gained border-line knowledge scores. Students in age category of 20-22 years had non-significantly earned a higher knowledge score than those students of other age categories. Conclusion: Knowledge of medical students regarding the pandemic was inadequate.
{"title":"Knowledge, attitude and practices of medical students regarding COVID-19 pandemic, Baghdad, Iraq 2022","authors":"Ghaida R. Hamid","doi":"10.5455/rmj.20230106050554","DOIUrl":"https://doi.org/10.5455/rmj.20230106050554","url":null,"abstract":"Objective: To explore the KAP of medical students in Baghdad city towards COVID-19, during the year 2022. Methodology: This cross-sectional study was carried out from April to June 2022 and included 2000 medical students from four medical schools in Baghdad. A systematic random sampling technique was used and every second student was included from four colleges with 4000 students in all four colleges. Thus, 2000 students were included and a self-structured questionnaire was used. Results: Complete esponses were received from 1738 students. Most were aged 20 to 22 years, approximately equally distributed as males and females. About 46.49% of the students gained border-line knowledge scores. Students in age category of 20-22 years had non-significantly earned a higher knowledge score than those students of other age categories. Conclusion: Knowledge of medical students regarding the pandemic was inadequate.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70839835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230206070704
Laith a, N. Younis
Objective: To evaluate the expertise and efforts of neonatal ward nurses in relation to phototherapy. Methodology: In this study, non-probability, purposive sampling was used and study was performed from January to February 2023. It included 62 nurses working in neonatal units in the city of Mosul. The study consisted of two parts: The first part was related to demographic information and second part was related to their knowledge of phototherapy in neonatal units. Results: Out of 62 nurses, 50 (80.65%) were male while 12 (19.35%) females. Mean age was 30.43 years. Nurses' knowledge about phototherapy was acceptable in 45% and good in 29%. Conclusion: Generally speaking, the nurses' understanding of how to administer phototherapy to neonates was inadequate to acceptable.
{"title":"Nurses knowledge regarding to phototherapy at neonatal care units in Mosul City, Iraq","authors":"Laith a, N. Younis","doi":"10.5455/rmj.20230206070704","DOIUrl":"https://doi.org/10.5455/rmj.20230206070704","url":null,"abstract":"Objective: To evaluate the expertise and efforts of neonatal ward nurses in relation to phototherapy. Methodology: In this study, non-probability, purposive sampling was used and study was performed from January to February 2023. It included 62 nurses working in neonatal units in the city of Mosul. The study consisted of two parts: The first part was related to demographic information and second part was related to their knowledge of phototherapy in neonatal units. Results: Out of 62 nurses, 50 (80.65%) were male while 12 (19.35%) females. Mean age was 30.43 years. Nurses' knowledge about phototherapy was acceptable in 45% and good in 29%. Conclusion: Generally speaking, the nurses' understanding of how to administer phototherapy to neonates was inadequate to acceptable.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70840198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj.20230213091322
A. Serafi, Dina M Qahwaji, Zahir Hussain, Mohammed A Bafail, Sumera Sohail
Objective: To determine the effect of the powder of Nigella sativa seeds (NSS) on serum low-density lipoprotein cholesterol (LDL-C) in female volunteers. Methodology: This study included 159 female volunteers aged 30-35 years determe effect of various doses of Nigella sativa (NS) on LDL-C serum levels of eight groups for the duration of nine months. Subjects in the first month (October 2021) were considered as the control (C) subjects. Same subjects in the remaining eight months (November 2021 to June 2022) were administered equal daily doses (1 gram/day) of the powder of Kalonji/NSS. Blood samples were obtained and Friedewald formula was employed for determining the levels of serum LDL-C. Results: The groups 1 to 8 altogether had significant decrease in LDL-C. Analysis of variance showed highly significant variations. Intergroup variations had p>0.0001. Various groups of LDL-C control range from 80-129.9 mg/dl under the influence of various doses of NS supplementation gave highly significant negative linear correlation. Conclusion: Administration of NS showed the levels of LDL-C in the central range of 80-100 mg/dl that might be considered as the physiological normal serum levels of LDL-C. Further studies are required in healthy subjects and patients having various hyperlipidaemic and other related disorders to understand the diagnostic and therapeutic significance of NS.
{"title":"Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers","authors":"A. Serafi, Dina M Qahwaji, Zahir Hussain, Mohammed A Bafail, Sumera Sohail","doi":"10.5455/rmj.20230213091322","DOIUrl":"https://doi.org/10.5455/rmj.20230213091322","url":null,"abstract":"Objective: To determine the effect of the powder of Nigella sativa seeds (NSS) on serum low-density lipoprotein cholesterol (LDL-C) in female volunteers. Methodology: This study included 159 female volunteers aged 30-35 years determe effect of various doses of Nigella sativa (NS) on LDL-C serum levels of eight groups for the duration of nine months. Subjects in the first month (October 2021) were considered as the control (C) subjects. Same subjects in the remaining eight months (November 2021 to June 2022) were administered equal daily doses (1 gram/day) of the powder of Kalonji/NSS. Blood samples were obtained and Friedewald formula was employed for determining the levels of serum LDL-C. Results: The groups 1 to 8 altogether had significant decrease in LDL-C. Analysis of variance showed highly significant variations. Intergroup variations had p>0.0001. Various groups of LDL-C control range from 80-129.9 mg/dl under the influence of various doses of NS supplementation gave highly significant negative linear correlation. Conclusion: Administration of NS showed the levels of LDL-C in the central range of 80-100 mg/dl that might be considered as the physiological normal serum levels of LDL-C. Further studies are required in healthy subjects and patients having various hyperlipidaemic and other related disorders to understand the diagnostic and therapeutic significance of NS.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70840277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj20220613092311
P. Gunawan, Kartika Hardiyani, I. Ugrasena
Objective: To analyze the Total Neuropathy Scale Pediatric Vincristine (TNS-PV) score as a vincristine induced peripheral neuropathy (VIPN) diagnostic tool. Methodology: This observational analytic study was conducted in Outpatient Pediatric Hematology Oncology Dr. Soetomo Hospital. The inclusion criteria were Acute Lymphoblastic Leukemia (ALL) children aged 4-18 years that had undergone chemotherapy treatment, received a cumulative dose of vincristine >12 mg/m2, had no muscle weakness and signed informed consent. The TNS-PV instrument were used to assess VIPN and nerve conduction studies (NCS) was used as the gold standard. Results: A total of 54 children were enrolled, two refused to sign the informed consent. About 60% were male children, 76.9% aged <10 years old, and 94% were ALL-L1. The TNS-PV had an area under the curve (AUC) of 0.638 (95% CI 0.531-0.834) with cut off value of 3.5. It had a sensitivity 87.9%; specificity 42.1%, positive predictive value 72.5%; negative predictive value (NPV) 66.6% and OR (Odds ratio) 5,273. Conclusion: TNS-PV score cannot replace NCS as the gold standard, but TNS-PV can be an alternative tool for diagnosing VIPN.
目的:分析小儿长春新碱全神经病变量表(TNS-PV)评分作为长春新碱诱导的周围神经病变(VIPN)的诊断工具。方法:本观察性分析研究在Soetomo医生医院儿科血液肿瘤科门诊进行。纳入标准是4-18岁的急性淋巴细胞白血病(ALL)儿童，接受化疗，长春新碱累积剂量bbb12mg /m2，无肌肉无力并签署知情同意。采用TNS-PV仪评估VIPN，以神经传导研究(NCS)为金标准。结果:共有54名儿童入组，其中2名拒绝签署知情同意书。约60%为男童，76.9%年龄<10岁，94%为ALL-L1。TNS-PV曲线下面积(AUC)为0.638 (95% CI 0.531 ~ 0.834)，截断值为3.5。灵敏度为87.9%;特异性42.1%，阳性预测值72.5%;阴性预测值(NPV) 66.6%， OR(优势比)5273。结论:TNS-PV评分不能代替NCS作为金标准，但TNS-PV可作为诊断VIPN的替代工具。
{"title":"Total Neuropathy Scale Pediatric Vincristine to detect vincristine induced peripheral neuropathy in children with Acute Lymphoblastic Leukemia","authors":"P. Gunawan, Kartika Hardiyani, I. Ugrasena","doi":"10.5455/rmj20220613092311","DOIUrl":"https://doi.org/10.5455/rmj20220613092311","url":null,"abstract":"Objective: To analyze the Total Neuropathy Scale Pediatric Vincristine (TNS-PV) score as a vincristine induced peripheral neuropathy (VIPN) diagnostic tool. Methodology: This observational analytic study was conducted in Outpatient Pediatric Hematology Oncology Dr. Soetomo Hospital. The inclusion criteria were Acute Lymphoblastic Leukemia (ALL) children aged 4-18 years that had undergone chemotherapy treatment, received a cumulative dose of vincristine >12 mg/m2, had no muscle weakness and signed informed consent. The TNS-PV instrument were used to assess VIPN and nerve conduction studies (NCS) was used as the gold standard. Results: A total of 54 children were enrolled, two refused to sign the informed consent. About 60% were male children, 76.9% aged <10 years old, and 94% were ALL-L1. The TNS-PV had an area under the curve (AUC) of 0.638 (95% CI 0.531-0.834) with cut off value of 3.5. It had a sensitivity 87.9%; specificity 42.1%, positive predictive value 72.5%; negative predictive value (NPV) 66.6% and OR (Odds ratio) 5,273. Conclusion: TNS-PV score cannot replace NCS as the gold standard, but TNS-PV can be an alternative tool for diagnosing VIPN.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70840351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj20221009060301
Mohammed A. Alzahrani
Objective: To find out how well Saudi Arabian healthcare workers followed infection control guidelines and determine whether there is a any relationship between the biographic profile of healthcare staff and their degree of compliance with infection control. Methodology: This descriptive-correlation study was conducted on healthcare workers from different Saudi Arabian hospitals. The study used a three-point Likert scale, and the rating scales used were “3” to indicate always, “2” to indicate sometimes, while “1” was used to indicate never. Results: Of 180 respondents, 62.8% were young adults, 73.3% were males, 68.3% were doctoral degree holders, 66.1% were licensed medical doctors, and 39.4% were advanced beginners. Saudi healthcare workers had an overall level of “high compliance” (mean=2.29). Chi-square test of independence (r2) revealed a statistically significant relationship between compliance to infection control practices and the following variables: age (p=0.0100), gender (p=0.0177), educational attainment (p=0.0001), and profession (p<0.0001). Conclusion: In Saudi Arabia, healthcare staff generally follow infection control procedures. Moreover, biographic profiles were significantly associated with the degree of infection prevention practice compliance by healthcare staff.
{"title":"Correlation between biographic profile and compliance to key performance indicators (KPI) for infection control among healthcare workers in Saudi Arabia: A cross-sectional study","authors":"Mohammed A. Alzahrani","doi":"10.5455/rmj20221009060301","DOIUrl":"https://doi.org/10.5455/rmj20221009060301","url":null,"abstract":"Objective: To find out how well Saudi Arabian healthcare workers followed infection control guidelines and determine whether there is a any relationship between the biographic profile of healthcare staff and their degree of compliance with infection control. Methodology: This descriptive-correlation study was conducted on healthcare workers from different Saudi Arabian hospitals. The study used a three-point Likert scale, and the rating scales used were “3” to indicate always, “2” to indicate sometimes, while “1” was used to indicate never. Results: Of 180 respondents, 62.8% were young adults, 73.3% were males, 68.3% were doctoral degree holders, 66.1% were licensed medical doctors, and 39.4% were advanced beginners. Saudi healthcare workers had an overall level of “high compliance” (mean=2.29). Chi-square test of independence (r2) revealed a statistically significant relationship between compliance to infection control practices and the following variables: age (p=0.0100), gender (p=0.0177), educational attainment (p=0.0001), and profession (p<0.0001). Conclusion: In Saudi Arabia, healthcare staff generally follow infection control procedures. Moreover, biographic profiles were significantly associated with the degree of infection prevention practice compliance by healthcare staff.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70840373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/rmj20220531071501
Ahmed AbdElbagy, Ahmed S Alkarani
Objective: To explore the perception of Saudi society about living kidney donation and to identify the trends towards the donation of a kidney. Methodology: This Quantitative cross-sessional community-based survey was carried-out from January to February 2020 among the Saudi population and included both natives and residents. We used convenience sampling technique. Perception about living kidney donation questionnaire was developed which included questions about knowledge regarding living kidney donation. Results: Out of 1295 participants, 567 (43.8%) were males and 728 (56.2%) females. The overall mean score of the public`s perception about living kidney donation was moderate (mean=5.90±1.18). There was a statistical difference (F=3.44, p<0.05) between age groups toward perception regarding living kidney donation, as older and female patients have a better perception of kidney donation than young adults and men. The trends of the Saudi community about kidney donation were moderate; most participants agreed to donate a kidney for humanitarian and religious purposes. Participants were aware that living kidney donation improves the quality of life of the recipient. Conclusion: Greater awareness about the center responsible for the organ transplantation can help willing donors to consent to future donation.
{"title":"The Public's trends toward Kidney Donation","authors":"Ahmed AbdElbagy, Ahmed S Alkarani","doi":"10.5455/rmj20220531071501","DOIUrl":"https://doi.org/10.5455/rmj20220531071501","url":null,"abstract":"Objective: To explore the perception of Saudi society about living kidney donation and to identify the trends towards the donation of a kidney. Methodology: This Quantitative cross-sessional community-based survey was carried-out from January to February 2020 among the Saudi population and included both natives and residents. We used convenience sampling technique. Perception about living kidney donation questionnaire was developed which included questions about knowledge regarding living kidney donation. Results: Out of 1295 participants, 567 (43.8%) were males and 728 (56.2%) females. The overall mean score of the public`s perception about living kidney donation was moderate (mean=5.90±1.18). There was a statistical difference (F=3.44, p<0.05) between age groups toward perception regarding living kidney donation, as older and female patients have a better perception of kidney donation than young adults and men. The trends of the Saudi community about kidney donation were moderate; most participants agreed to donate a kidney for humanitarian and religious purposes. Participants were aware that living kidney donation improves the quality of life of the recipient. Conclusion: Greater awareness about the center responsible for the organ transplantation can help willing donors to consent to future donation.","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70840494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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