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Outcomes of extracorporeal life support in hypothermic cardiac arrest: Revisiting ELSO guidelines. 低体温心脏骤停患者体外生命支持的效果:重新审视 ELSO 指南。
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-05 DOI: 10.1016/j.resuscitation.2024.110424
Konrad Mendrala, Tomasz Darocha, Michał Pluta, Anna Witt-Majchrzak, Hubert Hymczak, Ewelina Nowak, Tomasz Czarnik, Barbara Barteczko-Grajek, Wojciech Dąbrowski, Sylweriusz Kosiński, Paweł Podsiadło

Aim of the study: Predictive factors for poor outcomes in hypothermic cardiac arrest (HCA) differ from those in normothermic out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate the outcomes of extracorporeal life support (ECLS) in HCA patients who may not be considered eligible based on the guidelines set by the Extracorporeal Life Support Organization (ELSO).

Methods: A retrospective multicentre study included 127 HCA patients, divided into two groups: those meeting the ELSO eligibility criteria for ECLS, and those with at least one of the following ELSO exclusion criteria: age over 70 years, unwitnessed cardiac arrest, or asystole.

Results: Among the 62 patients who met the ELSO criteria, 38 (61 %) survived to hospital discharge, with 34 (89 %) achieving a favourable neurological outcomes. Of the 65 patients who received ECLS despite not meeting ELSO criteria, 24 (37 %) survived to discharge, with 20 (83 %) demonstrating a favourable neurological outcomes. In patients not meeting one or two ELSO criteria, survival rates were 18 of 47 (38 %) and 6 of 16 (38 %) respectively, with 83 % of survivors in both groups achieving favourable neurological outcomes. The two patients who failed to meet all three ELSO criteria did not survive.

Conclusion: Qualification of patients with hypothermic cardiac arrest for ECLS rewarming should not be strictly based on guidelines for normothermic cardiac arrest, as this may result in not initiating potentially life-saving treatment for patients who could have favourable prognoses for survival with good neurological outcomes.

研究目的:低体温型心脏骤停(HCA)患者不良预后的预测因素与正常体温型院外心脏骤停(OHCA)患者不同。本研究旨在评估根据体外生命支持组织(ELSO)制定的指南可能不符合条件的 HCA 患者使用体外生命支持(ECLS)的结果:一项回顾性多中心研究纳入了127例HCA患者,将其分为两组:符合ELSO体外生命支持组织资格标准的患者,以及至少符合以下一项ELSO排除标准的患者:年龄超过70岁、未经目击的心脏骤停或心跳停止:在 62 名符合 ELSO 标准的患者中,有 38 人(61%)存活到出院,其中 34 人(89%)获得了良好的神经功能预后。在不符合ELSO标准但接受了ECLS治疗的65名患者中,有24人(37%)存活到出院,其中20人(83%)的神经系统状况良好。在不符合一项或两项 ELSO 标准的患者中,存活率分别为 47 例中的 18 例(38%)和 16 例中的 6 例(38%),两组中均有 83% 的存活者获得了良好的神经功能预后。未能满足所有三个ELSO标准的两名患者未能存活:结论:对低体温性心脏骤停患者进行 ECLS 复温的资格审查不应严格依据正常体温性心脏骤停的指南,因为这可能导致无法为预后良好、神经系统状况良好的存活患者启动可能挽救生命的治疗。
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引用次数: 0
53 Incidence, risk factors and clinical outcome of ventilator associated pneumonia in cardiac arrest patients treated with selective digestive decontamination (SDD) protocol. 53 采用选择性消化道净化(SDD)方案治疗的心脏骤停患者呼吸机相关肺炎的发病率、风险因素和临床结果。
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00371-X
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引用次数: 0
44 Association between scene time interval and clinical outcomes according to key Utstein factors in out-of-hospital cardiac arrest 44 院外心脏骤停患者的关键 Utstein 因素与现场时间间隔和临床结果之间的关系
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00362-9
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引用次数: 0
31 The “ceiling effect” of bystander CPR among three Asian countries: descriptive study of national OHCA databases 31 亚洲三国旁观者心肺复苏的 "天花板效应":国家 OHCA 数据库的描述性研究
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00350-2
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引用次数: 0
6 Simulation based Womens Education Development Day training for Nurses & Midwives in Obstetric emergencies: Experiences from Sidra Medicine 6 为护士和助产士提供产科急诊模拟妇女教育发展日培训:Sidra 医学中心的经验
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00329-0
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引用次数: 0
60 Pre-hospital post-arrest anaesthesia for reintubation of an extraglottic airway to an endotracheal tube with midazolam vs. propofol - results of a multicentre observational study 60 用咪达唑仑与异丙酚进行声门外气道与气管插管再插管的院前急救后麻醉--多中心观察研究结果
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00377-0
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引用次数: 0
66 The Impact of CPR Technique on Post-Arrest Neurologic Outcomes In Television Medical Dramas 66 电视医疗剧中心肺复苏技术对复苏后神经系统结果的影响
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00383-6
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引用次数: 0
91 Association Between Hemoglobin and Neurological Outcome in the Elderly after Cardiac Arrest: A Retrospective Study 91 心脏骤停后老年人血红蛋白与神经系统预后的关系:回顾性研究
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00405-2
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引用次数: 0
56 Improving Cardiopulmonary Resuscitation Effectiveness Through the Use of a Smartphone Application Among Trained and Non-Trained Adults in Greece. 56 通过在希腊受过培训和未受过培训的成年人中使用智能手机应用程序提高心肺复苏的效果。
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00373-3
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引用次数: 0
100 Near-Infrared Spectroscopy as a surrogate for Vital Organ Perfusion during Cardiopulmonary Resuscitation in a Porcine Model of Cardiac Arrest 100 用近红外光谱替代猪心搏骤停模型中心肺复苏过程中的重要器官灌注量
IF 6.5 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-10-30 DOI: 10.1016/S0300-9572(24)00414-3
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引用次数: 0
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Resuscitation
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