Pub Date : 2023-04-03DOI: 10.25135/rnp.389.2301.2694
D. Battal, F. Alkaş, K. Kocadal, İ. Çalış, Ş. Saygi
{"title":"Evaluation of the Chemotactic and Genotoxic Effects of Selected Cycloartane-type Glycosides on Caenorhabditis elegans","authors":"D. Battal, F. Alkaş, K. Kocadal, İ. Çalış, Ş. Saygi","doi":"10.25135/rnp.389.2301.2694","DOIUrl":"https://doi.org/10.25135/rnp.389.2301.2694","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48691392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: A newly discovered cleistanthane-type diterpenoid named incarnatin A ( 1 ) was isolated from Peniophora incarnate , an endophytic fungus obtained from the roots of Ligusticum chuanxiong . Its absolute configuration was unambiguously elucidated by spectroscopic means including HRMS and NMR combined with ECD calculations. Transcriptome sequencing indicated that 1 could inhibit angiogenesis.
{"title":"A Previously Undescribed Cleistanthane-Type Diterpenoid from Peniophora incarnate","authors":"Yun Deng, Mei-Mei Li, Wenxiu Guo, Congcong Li, Xue-yan Huo, Yunjie Hu, D. Guo, Li-jun Huang, Yu Jiang","doi":"10.25135/rnp.374.2210.2619","DOIUrl":"https://doi.org/10.25135/rnp.374.2210.2619","url":null,"abstract":": A newly discovered cleistanthane-type diterpenoid named incarnatin A ( 1 ) was isolated from Peniophora incarnate , an endophytic fungus obtained from the roots of Ligusticum chuanxiong . Its absolute configuration was unambiguously elucidated by spectroscopic means including HRMS and NMR combined with ECD calculations. Transcriptome sequencing indicated that 1 could inhibit angiogenesis.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46407871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-25DOI: 10.25135/rnp.385.2211.2628
Huseyin Aksit
{"title":"Isolation of Undescribed Biflavonoid from Potamogeton pusillus L. and Antidiabetic Activity Properties","authors":"Huseyin Aksit","doi":"10.25135/rnp.385.2211.2628","DOIUrl":"https://doi.org/10.25135/rnp.385.2211.2628","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47519437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-25DOI: 10.25135/rnp.358.2207.2522
Dragana Drakul, Milan Kulić, D. Sokolović, Jelena Kordić-Bojinović, S. Milovanović, D. Blagojević
: Satureja montana L. (SM) has a long traditional use as a spice and a medicine for various gastrointestinal disorders, including painful spasms and diarrhea. Contrary to conventional drugs, administration of SM and its extracts are considered safe. Previous studies have shown that the essential oils (EOs) of SM from different areas are rich in monoterpenes, sesquiterpenes, diterpens, and phenolic compounds, including flavonoids, tannins, and acids with great composition variability. Determination of composition of EO from Herzegovinian SM done by gas chromatography-flame ionization detection and gas chromatography mass spectrometry (GC-FID and GC/MS, respectively) revealed carvacrol as a primary substance followed by γ -terpinene, p -cymene, and β -caryophyllene. Ex vivo spasmolitic activity caused by EO was evident in different types of isolated rat ileum function with the most potent effect on spontaneous activity followed by electrical field stimulation and KCl- and CaCl 2 -induced activity. SMEO produced in vivo antidiarreal activity on castor oil-induced diarrhea in young rats and showed the potential to cause a decrese water content in the feces of adult Wistar rats.This study indicates that effects of SM on the intestinum could be mediated through combination of Kv channel activation and Ca channel blockade, but additional mechanisms might be involved. The results of this study corroborate the traditional use of SM as antispasmodic, antidiarrheal, and antisecretory agents. this are consistent with traditional use of SMs as antispasmodic, antidiarrheal, and antisecretory medicine in intestinal disorders that involve excessive smooth muscle contractility.
{"title":"Essential Oil of Satureja montana L. from Herzegovina: Assessment of Composition, Antispasmodic, and Antidiarrheal Effects","authors":"Dragana Drakul, Milan Kulić, D. Sokolović, Jelena Kordić-Bojinović, S. Milovanović, D. Blagojević","doi":"10.25135/rnp.358.2207.2522","DOIUrl":"https://doi.org/10.25135/rnp.358.2207.2522","url":null,"abstract":": Satureja montana L. (SM) has a long traditional use as a spice and a medicine for various gastrointestinal disorders, including painful spasms and diarrhea. Contrary to conventional drugs, administration of SM and its extracts are considered safe. Previous studies have shown that the essential oils (EOs) of SM from different areas are rich in monoterpenes, sesquiterpenes, diterpens, and phenolic compounds, including flavonoids, tannins, and acids with great composition variability. Determination of composition of EO from Herzegovinian SM done by gas chromatography-flame ionization detection and gas chromatography mass spectrometry (GC-FID and GC/MS, respectively) revealed carvacrol as a primary substance followed by γ -terpinene, p -cymene, and β -caryophyllene. Ex vivo spasmolitic activity caused by EO was evident in different types of isolated rat ileum function with the most potent effect on spontaneous activity followed by electrical field stimulation and KCl- and CaCl 2 -induced activity. SMEO produced in vivo antidiarreal activity on castor oil-induced diarrhea in young rats and showed the potential to cause a decrese water content in the feces of adult Wistar rats.This study indicates that effects of SM on the intestinum could be mediated through combination of Kv channel activation and Ca channel blockade, but additional mechanisms might be involved. The results of this study corroborate the traditional use of SM as antispasmodic, antidiarrheal, and antisecretory agents. this are consistent with traditional use of SMs as antispasmodic, antidiarrheal, and antisecretory medicine in intestinal disorders that involve excessive smooth muscle contractility.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48765758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-22DOI: 10.25135/rnp.388.2302.2714
De-Liang Zhang, Lu-Di Zhai, Wei-ping Gao, Li‐Ting Liu, K. Zhang
{"title":"Trichonafurin A: a New γ-Lactone Compound from the Marine-Derived Fungus Trichoderma atroviride ZW-7","authors":"De-Liang Zhang, Lu-Di Zhai, Wei-ping Gao, Li‐Ting Liu, K. Zhang","doi":"10.25135/rnp.388.2302.2714","DOIUrl":"https://doi.org/10.25135/rnp.388.2302.2714","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42146230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-22DOI: 10.25135/rnp.384.2301.2685
Wen-xing Liu, Ying-Jun Zhang, Min Zhou, Ping Zhao
{"title":"A New Ingenane Diterpenoid from Euphorbia jolkinii","authors":"Wen-xing Liu, Ying-Jun Zhang, Min Zhou, Ping Zhao","doi":"10.25135/rnp.384.2301.2685","DOIUrl":"https://doi.org/10.25135/rnp.384.2301.2685","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45881173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A New Megastigmane Glycoside and Anti-Inflammatory Bibenzyls from the Stems of Dendrobium henanense","authors":"Fengqing Xu, Siyu Wu, Shi-cai Qin, Chui-Jian Kong, Renzhong Wang, De-Peng Wu","doi":"10.25135/rnp.382.2211.2626","DOIUrl":"https://doi.org/10.25135/rnp.382.2211.2626","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43557491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Phenanthrene and An Undescribed Alkaloid from the Roots of Stephania tetrandra","authors":"Fengqing Xu, Renzhong Wang, Siyu Wu, Jinye Xu, De-Peng Wu","doi":"10.25135/rnp.381.2212.2663","DOIUrl":"https://doi.org/10.25135/rnp.381.2212.2663","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44070683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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