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Adnexal and clinical effects of myoinositol and lipoic acid in PCOs patients 肌醇和硫辛酸对PCOs患者的辅助及临床作用
Pub Date : 2023-03-27 DOI: 10.15406/ipcb.2023.09.00277
P. Juan, Perruzza Marta, Donfrancesco Cristina, R. Giuseppe
Background: Polycistic ovary syndrome (PCOs) is one of the most common endocrine and metabolic disorders in premenopausal women. Our team aimed to know an eventual significant effect of the therapy based on an Alfa Lipoic Acid (ALA)/Myoinositol (Myo) combined drug on adnexal parameters as assessed by ultrasound and follow up clinical analysis. Methods: The following represents the results of a prospective trial considering data from thirty italian nulliparous women considered for the study, chosen from an initial group of fifty-eight women, compared to data taken from a healthy women group paired by age and nulliparous status. The mean age was 30.1 years old. Patients underwent a Myoinositol (400 mg) plus ALA (800 mg) regimen twice a day in a continued fashion in a twenty four months period. Ultrasound examinations were coincident with the fifth day of menstrual period and were set as follows: Time 0 (first evaluation), Time 12 (after twelve months) and finally Time 24 (after 24 months). Results: Comparisons were performed between Time 0 and Time 12 paired data, No significant ultrasound parameters differences were found between paired patients regarding: endometrial width, number of follicles and ovarian volume at the time of the trial. Regarding clinical symptoms, menstrual pelvic pain significantly decreased after a mean time of about four months and menstrual cycle tended to be regular in 12 from 30 patients after eight months under therapy. Parameters dealing with ultrasound color Doppler velocimetry status were studied considering other twelve months and will be described in a further report considering only ultrasound parameters. Conclusions: Considering the preliminary results of this study, we may hypothesize that Inositol may block the vascular effects of hyperadrogenism, and that the ALA in addition may play a role regarding anti oxidant and anti inflammatory pathways
背景:多囊卵巢综合征(PCOs)是绝经前妇女最常见的内分泌代谢疾病之一。我们的团队旨在通过超声评估和随访临床分析,了解基于α硫辛酸(ALA)/肌醇(Myo)联合药物治疗对附件参数的最终显著影响。方法:以下是一项前瞻性试验的结果,该试验考虑了从58名妇女的初始组中选择的30名意大利未生育妇女的数据,并将其与按年龄和未生育状况配对的健康妇女组的数据进行了比较。平均年龄为30.1岁。患者接受肌醇(400毫克)加ALA(800毫克)方案,每天两次,持续24个月。超声检查与月经第5天同时进行,时间设置如下:时间0(第一次评估),时间12(12个月后),时间24(24个月后)。结果:比较时间0和时间12的配对数据,配对患者在试验时子宫内膜宽度、卵泡数量、卵巢体积等超声参数均无显著差异。临床症状方面,经期盆腔疼痛平均约4个月后明显减轻,经治疗8个月后,30例患者中有12例月经周期趋于正常。处理超声彩色多普勒测速状态的参数考虑到其他十二个月进行了研究,并将在进一步的报告中描述仅考虑超声参数。结论:考虑到本研究的初步结果,我们可以假设肌醇可能阻断了肾上腺素增生性的血管作用,ALA也可能在抗氧化和抗炎途径中发挥作用
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引用次数: 0
Perinatal stroke and overlapping clinical presentation with HIE; studying practical diagnostic and management challenges through observational analysis of a single tertiary centre stroke patients 围产期卒中与HIE重叠临床表现通过对单一三级中心脑卒中患者的观察分析,研究实际诊断和管理挑战
Pub Date : 2023-03-06 DOI: 10.15406/ipcb.2023.09.00276
Gupta R, N. M, Chetcuti Ganado Claudia
Background: While therapeutic hypothermia is accepted as a standard of care for improving neurological outcome for HIE patients, evidence of its benefits for neonatal stroke is lacking. Neurological presentations of HIE and neonatal stroke can be difficult to distinguish and indeed neonatal stroke can coexist with HIE. Our observational analysis of a single centre cohort of stroke infants with MRI diagnosis highlights the practical challenges for distinguishing between the two groups and reaching an early definitive diagnosis to inform appropriate treatment. Methods: A retrospective cohort study of term neonates >37 weeks gestation born between May 2011 and April 2020 born at a specialised NICU network in the East of England with a principal diagnosis of neonatal stroke were obtained from Badgernet data. Results: 81% of infants (13/16) had sentinel events around delivery. 50% (8/16) of infants were therapeutically cooled. Of the 8 cooled infants only 3 (37%) of cooled infants fulfilled both Toby A and B criteria. Infants who received therapeutic hypothermia were more likely to present with early onset seizures (5/8) than infants who were not cooled (1/8) (p=0.019) . 6 of the 8 non-cooled infants compared to 2of the 8 cooled infants (p=0.03) had a higher seizure burden requiring escalation of antiepileptic medication to second line or need for maintenance treatment. Conclusion: Infants with neonatal stroke who present with early seizures are more likely to receive therapeutic hypothermia despite failure to fulfil both Toby A and B criteria. Early suspicion to inform management can be obtained more effectively from CFM while cranial ultrasound findings are generally non-specific. A normal CFM background, unilateral abnormal background and unilateral seizure activity are highly suggestive of neonatal stroke.
背景:虽然治疗性低温治疗被认为是改善HIE患者神经系统预后的标准治疗方法,但其对新生儿中风的益处尚缺乏证据。HIE和新生儿中风的神经学表现很难区分,事实上新生儿中风可以与HIE共存。我们对MRI诊断的脑卒中婴儿单中心队列的观察性分析强调了区分两组并达到早期明确诊断以告知适当治疗的实际挑战。方法:从Badgernet数据中获取2011年5月至2020年4月在英格兰东部专科NICU网络出生、主要诊断为新生儿卒中的>37周妊娠足月新生儿的回顾性队列研究。结果:81%的婴儿(13/16)在分娩前后发生前哨事件。50%(8/16)的婴儿采用治疗性冷却。在8名冷却婴儿中,只有3名(37%)冷却婴儿同时满足Toby A和B标准。接受低温治疗的婴儿比未接受低温治疗的婴儿(1/8)更容易出现早发性癫痫发作(5/8)(p=0.019)。8名未降温的婴儿中有6名,而8名降温的婴儿中有2名(p=0.03)癫痫发作负担更高,需要将抗癫痫药物升级到二线或需要维持治疗。结论:出现早期癫痫发作的新生儿中风患儿更有可能接受低温治疗,尽管未能满足Toby A和B标准。CFM可以更有效地获得早期怀疑以告知治疗,而颅超声结果通常是非特异性的。CFM背景正常,单侧异常背景和单侧癫痫活动高度提示新生儿中风。
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引用次数: 0
Thirty-five years of HIV/AIDS in Chilean children and adolescents 智利儿童和青少年35年来的艾滋病毒/艾滋病情况
Pub Date : 2023-02-27 DOI: 10.15406/ipcb.2023.09.00275
Elba Wu Hupat
The history of HIV/AIDS in Chilean children is described, from the detection of the first case in 1987 to date, with the main advances obtained by the Paediatric HIV/AIDS Care Programme, SOCHIPE/MINSAL. Thefollow-up and management of children and adolescents in this Program is described
本书描述了智利儿童艾滋病毒/艾滋病的历史,从1987年发现第一例病例至今,主要进展是由儿童艾滋病毒/艾滋病护理方案(SOCHIPE/MINSAL)取得的。本项目对儿童和青少年的跟踪和管理进行了描述
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引用次数: 0
Oral versus intravenous iron therapy for correction of iron deficiency anaemia in pregnancy 口服与静脉注射铁治疗纠正妊娠缺铁性贫血
Pub Date : 2023-02-01 DOI: 10.15406/ipcb.2023.09.00274
N. Hooja, Andaleeb Fatima
Background: The high prevalence of anaemia in pregnancy has serious adverse consequences in both mother and baby. Management of anaemia in pregnancy should be given great importance in obstetric practice.The study was undertaken to compare the efficacy of oral iron (ferrous sulphate) and intravenous iron sucrose complex in the management of moderate anaemia in pregnancy. Method: A randomized comparative hospital–based longitudinal analysis was conducted in the Department of Obstetrics and Gynaecology of a tertiary care hospital, involving 70 women with haemoglobin between 7- 9.9 g/dl and serum ferritin < 50 mcg/l, attending antenatal clinic. Intravenous iron sucrose complex was given in one group and tablet ferrous sulfate (100 mg elemental iron) to the oral group. Treatment efficacy was assessed by measurement of haemoglobin and reticulocytes on days 8, 15, 21 and 30 and ferritin on day 30. Result: An increase in haemoglobin was observed in both groups, rising from 8.26 ±0.764g/dl to 11.08± 0.71g/dl in the intravenous group and from 8.14±0.767 g/dl to 10.98 ±0.61 g/dl on day 30 in the oral group. S.ferritin on day 30 was significantly higher in the intravenous group. The side effects in both groups were negligible though there were there were 3 dropouts due to adverse effects. Conclusion : Both oral ferrous sulphate and intravenous iron sucrose complex are safe, convenient and effective in treatment of iron deficiency anaemia in pregnant women with negligible side effects, but intravenous iron sucrose complex is better in improving serum iron and in restoring maternal iron stores
背景:妊娠期贫血的高发对母亲和婴儿都有严重的不良后果。妊娠期贫血的管理应在产科实践中给予高度重视。该研究旨在比较口服铁(硫酸亚铁)和静脉注射蔗糖铁复合物治疗妊娠期中度贫血的疗效。方法:在某三级医院妇产科进行随机比较医院纵向分析,纳入70例在产前门诊就诊的血红蛋白在7- 9.9 g/dl,血清铁蛋白< 50 mcg/l的妇女。一组给予蔗糖铁络合物静脉注射,口服组给予硫酸亚铁片(元素铁100 mg)。第8天、第15天、第21天、第30天测定血红蛋白和网织红细胞,第30天测定铁蛋白,评估治疗效果。结果:两组患者血红蛋白均有所升高,静脉注射组从8.26±0.764g/dl升高至11.08±0.71g/dl,口服组从8.14±0.767 g/dl升高至10.98±0.61 g/dl。静脉注射组第30天s .铁蛋白明显升高。两组的副作用都可以忽略不计,但有3人因不良反应而退出。结论:口服硫酸亚铁和静脉注射蔗糖铁复合物治疗孕妇缺铁性贫血安全、方便、有效,副作用可忽略不计,但静脉注射蔗糖铁复合物在改善血清铁和恢复母体铁储备方面效果更好
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引用次数: 0
Magnitude and factors associated with anemia among pregnant woman attending antenatal care in asella town arsi oromia, Ethiopia 埃塞俄比亚阿西奥罗米亚asella镇参加产前保健的孕妇贫血程度和相关因素
Pub Date : 2023-01-25 DOI: 10.15406/ipcb.2023.09.00273
Melese Tadesse Aredo, Hailu Fekadu Demise, Emebet Daba Megersa
Background: Anemia during pregnancy affects both the mother and the fetus and is a leading cause of morbidity and mortality in pregnant women in underdeveloped nations. Studies were undertaken in many sections of the nation to assess the prevalence of anemia and predictor variables despite its well-known negative impact on health; however, the topic in Asella has not been well addressed or investigated. Objective: From March 15 to April 15, 2017, pregnant women receiving Antenatal Care services at a public health center in Asella, Ethiopia, were assessed for the prevalence of anemia and its contributing factors. Methods and materials: A facility-based cross-sectional study design was used. Data were collected using an interviewer-administered questionnaire complemented by laboratory tests. Data were collected by face-to-face interviews using a pre-tested, semi-structured questionnaire and the Hg test. EPI ENFO version 7.1 was used for data clearing and documentation, and SPSS version 21 was used for data analysis. The predictors of anemia were found using a logistic regression analysis. To determine the strength of the association, crude and adjusted OR were computed along with their respective 95% CI. P 0.05 was also regarded as statistically significant. Result: The magnitude of anemia was 46.1% in this investigation utilizing a cut level of hemoglobin of 11 g/dl. Anemia was strongly linked with the occupation of merchant (AOR=0.066,95%CI=0.006,0.761), third trimester gestational age (AOR=2.631,95%CI=1.272,5.44), lack of nutrition education (AOR=1.723,95%CI=1.010,2.939), and consumption of wheat as a staple food (AOR=3.288,95%CI=1.765,6.128). Conclusion and recommendation: In the study area, anemia is discovered to be a serious public health issue. A special focus needs to be placed on raising awareness about the consumption of iron-rich and diverse foods among pregnant women and people who work as housewives
背景:妊娠期贫血对母亲和胎儿都有影响,是欠发达国家孕妇发病和死亡的主要原因。尽管众所周知贫血对健康有负面影响,但仍在全国许多地区进行了研究,以评估贫血的患病率和预测变量;然而,在Asella,这个话题还没有得到很好的解决或调查。目的:对2017年3月15日至4月15日在埃塞俄比亚Asella某公共卫生中心接受产前保健服务的孕妇进行贫血患病率及其影响因素评估。方法和材料:采用基于设施的横断面研究设计。数据收集采用访谈者填写的问卷,辅以实验室测试。数据通过面对面访谈收集,使用预先测试的半结构化问卷和汞测试。使用EPI ENFO 7.1版本进行数据清理和记录,使用SPSS 21版本进行数据分析。使用逻辑回归分析发现贫血的预测因子。为了确定相关性的强度,计算了粗OR和调整OR及其各自的95% CI。p0.05也被认为有统计学意义。结果:贫血程度为46.1%的调查利用血红蛋白削减水平为11克/分升。贫血与商人职业(AOR=0.066,95%CI=0.006,0.761)、孕晚期胎龄(AOR=2.631,95%CI=1.272,5.44)、缺乏营养教育(AOR=1.723,95%CI=1.010,2.939)、以小麦为主食(AOR=3.288,95%CI=1.765,6.128)密切相关。结论和建议:在研究区域,贫血被发现是一个严重的公共卫生问题。需要特别重视提高孕妇和家庭主妇对摄入富含铁和多样化食物的认识
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引用次数: 0
Prevalence of Trichomoniasis among pregnant women attending antenatal clinic of the general hospital Dutsin-ma, Katsina State 在卡齐纳州Dutsin-ma综合医院产前门诊就诊的孕妇中滴虫病的患病率
Pub Date : 2023-01-20 DOI: 10.15406/ipcb.2023.09.00271
James Bemshima Orpin, A. S, Eberemu Nc
This study was carried out to investigate the Prevalence of Trichomoniasis among Pregnant Women attending General Hospital Dutsin-Ma. A total number of 181 high vaginal swab (HVS) samples were examined in General Hospital Dutsin-ma. Fifty-six (30.9%) samples were positive considering the risk factors of Age, number of sexual partners, method of douche and type of latrine. The age range of 26-30 had high incidence of 36% while 36-40 recorded 23%. With respect to the number of sexual partners, participants with four (4) sexual partners had the highest incidence of 60%. Participants with three (3) sexual partners had the incidence of 41%, participants with two (2) sexual partners had the incidence of 31%, while participants with one (1) sexual partner had the prevalence of 27%. Considering the method of douche, it showed that participants that use water only to douche had the highest incidence of 46%, participants who use water and soap to douche had the incidence of 39%, and those that use herbal concoctions to douche had the incidence of 7.5%. Based on type of latrine, participants who use pit latrine or public toilets had the highest prevalence of 34%, and participants who use water closet had the incidence of 25%.
摘要本研究旨在了解在杜新马综合医院就诊的孕妇中滴虫病的流行情况。在杜新马总医院共检查了181例高阴道拭子(HVS)样本。考虑到年龄、性伴侣数量、冲洗方式和厕所类型等危险因素,56份(30.9%)样本呈阳性。26 ~ 30岁发病率最高,为36%,36 ~ 40岁发病率最高,为23%。就性伴侣的数量而言,拥有四(4)个性伴侣的参与者发病率最高,为60%。有三(3)个性伴侣的参与者发病率为41%,有两(2)个性伴侣的参与者发病率为31%,而有一(1)个性伴侣的参与者发病率为27%。从冲洗方法来看,仅用水冲洗的参与者发病率最高,为46%,用水和肥皂冲洗的参与者发病率为39%,使用草药调和剂冲洗的参与者发病率为7.5%。根据厕所类型,使用坑式厕所或公共厕所的参与者发病率最高,为34%,使用抽水马桶的参与者发病率为25%。
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引用次数: 0
Transverse uterine fundal incision - an alternative to vertical uterine incision for anterior placenta accreta involving the entire uterine wall: a case report 子宫底部横向切口-一种替代垂直子宫切口前胎盘增生累及整个子宫壁:1例报告
Pub Date : 2022-12-15 DOI: 10.15406/ipcb.2022.08.00270
Shweta Mathur, Neha Gupta
The placenta accreta spectrum is on rise. If the placenta is covering the entire anterior uterine wall, there are definite challenges involved in delivering the fetus without exsanguination and with minimal maternal blood loss. We present a case report that highlights the use of transverse uterine fundal incision (TFUI) in an anterior placenta previa with accreta involving the entire uterine wall. It can be considered as an option to vertical uterine incision in such cases where the patient is not desirous of future fertility and caesarean hysterectomy is planned
胎盘增生谱呈上升趋势。如果胎盘覆盖了整个子宫前壁,那么在不放血和母体失血最少的情况下分娩胎儿无疑是一个挑战。我们提出一个病例报告,强调使用横向子宫底切口(TFUI)在前置胎盘增生累及整个子宫壁。当患者不希望将来生育,计划剖宫产时,可考虑子宫垂直切口
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引用次数: 0
A comparative study between Patwardhan technique and push & pull method in women undergoing second stage of labor 帕特瓦丹法与推拉法在产妇第二产程中的比较研究
Pub Date : 2022-12-05 DOI: 10.15406/ipcb.2022.08.00268
Gargi Deshmukh, Tapan Bandyopadhyay, A. Kakade, A. Ghosh
Introduction: Obstructed labor with the fetal head impacted in the pelvis is an obstetric complication that requires caesarean delivery with skilful handling in an organized manner to avoid serious maternal and neonatal morbidity. The present study was undertaken to compare the Patwardhan technique with push and pull methods and also to evaluate the safety of Patwardhan technique. Material & methods: Study based on a total 90 pregnant women, of age 18 – 35 years with singleton pregnancy in second stage of labor with deeply impacted head, cases examined in labor room who gave consent and fulfilled inclusion criteria including inpatient admissions and referral randomly allocated in three groups 30 each.1. Patwardhan technique. 2. Push Technique 3. Pull technique. Results: Age, gestational age and duration of labor of the subjects in three were similar. There was significantly less incidence of uterine incision extension to either side, board ligament hematoma, intra-operative blood loss and traumatic Postpartum hemorrhage in subjects undergoing Patwardhan’s technique. With regards to neonatal outcome, wound infection, foetal injury and mean duration of hospital stay were significantly less in Patwardhan’s technique. Birth weight and APGAR scores were similar in all groups. Conclusion: There was less incidence of maternal and foetal morbidity in Patwardhan’s technique which makes it a preferred choice for management during second stage of labor
导语:胎头嵌塞在骨盆中的难产是一种产科并发症,需要有组织的熟练处理的剖宫产,以避免严重的孕产妇和新生儿发病率。本研究是为了比较帕特瓦尔丹技术与推拉方法,并评估帕特瓦尔丹技术的安全性。材料与方法:研究对象为90例年龄在18 - 35岁的二产程单胎妊娠且头部深度撞击的孕妇,在产房检查,同意并符合住院和转诊标准的病例,随机分为三组,每组30例1。Patwardhan技术。2. 3.推法把技术。结果:3例产妇年龄、胎龄、产程相近。采用Patwardhan技术的患者子宫切口向两侧延伸、板韧带血肿、术中出血量及外伤性产后出血的发生率均明显降低。在新生儿结局方面,Patwardhan技术的伤口感染、胎儿损伤和平均住院时间显著缩短。各组出生体重和APGAR评分相似。结论:帕特瓦丹法产妇和胎儿发病率低,是第二产程处理的首选方法
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引用次数: 0
Satisfaction status and its associated factors on delivery service provided among women who gave birth at hawassa university comprehensive specialized hospital in southern Ethiopia 2022 埃塞俄比亚南部阿瓦萨大学综合专科医院分娩妇女对分娩服务的满意度及其相关因素
Pub Date : 2022-10-19 DOI: 10.15406/ipcb.2022.08.00267
Temesgen Geta, Merid Mekine, Nebiyat Kasa
Background: Despite the Ethiopian federal ministry of health implementing compassionate, respectful, and caring as one of the health sector transformation agendas to increase health service utilization, the level of maternal satisfaction with institutional delivery is still low and varies from region to region. In addition, no previous study was conducted in this study area. Therefore, the main objective of the study was to assess the level of women's satisfaction with institutional delivery services and associated factors among mothers who gave birth at Hawassa University's comprehensive specialized Hospital. Methods and Materials: Institutional based quantitative cross-sectional study was employed from April to May 2022 at Hawassa University's comprehensive specialized hospital. A total of 265 women who came to delivery service were included in the study and systematic sampling techniques was used to select study participant. A semi-structured questionnaire was used to collect data. The data was entered into EPI Data 3.1 version and transported to SPSS version 25 for data analysis. Binary and multi-regression were done for predictor variables associated at p-value <0.05 with the dependent variable. Result: A total of 265 mothers fully responded, making a response rate of 95.3%. This study found that 63% of study participants were satisfied and 37% of them were unsatisfied with the delivery and labor service. Participants' occupation, last pregnancy wanted, health conditions of the mother during and after delivery, media exposure to institutional delivery, total duration of labor, a surgical procedure done for women, the provider gives periodic updates on the progress of labor and explained what is being done and that to be expected were statistically associated with satisfaction status. Conclusion: The study showed that the overall satisfaction of the women with the delivery service provided by health care providers in the study area was relatively low. Therefore, all stakeholders should take immediate and appropriate action on those identified factors.
背景:尽管埃塞俄比亚联邦卫生部将同情、尊重和关怀作为卫生部门转型议程之一,以提高卫生服务的利用率,但孕产妇对机构分娩的满意度仍然很低,而且因地区而异。此外,在此研究领域未进行过相关研究。因此,研究的主要目的是评估在哈瓦萨大学综合专科医院分娩的母亲对机构分娩服务的满意程度及其相关因素。方法与材料:采用基于机构的定量横断面研究,于2022年4 - 5月在哈瓦萨大学综合专科医院进行。本研究共纳入265名前来分娩的妇女,采用系统抽样技术选择研究对象。采用半结构化问卷收集数据。数据录入EPI data 3.1版本,传输至SPSS 25版本进行数据分析。对p值<0.05与因变量相关的预测变量进行二元和多元回归。结果:265位母亲充分回复,回复率为95.3%。本研究发现,63%的研究参与者对分娩和劳动服务感到满意,37%的人不满意。参与者的职业、上次怀孕的要求、分娩期间和分娩后母亲的健康状况、媒体对机构分娩的报道、分娩总持续时间、为妇女进行的外科手术、提供者定期提供分娩进展的最新情况,并解释正在进行的工作和预期的工作,这些在统计上与满意度有关。结论:研究表明,研究区妇女对卫生保健提供者提供的分娩服务的总体满意度较低。因此,所有利益相关者都应该针对这些确定的因素立即采取适当的行动。
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引用次数: 0
Clinical manifestations, complications and management of chickenpox infection in pediatric 小儿水痘感染的临床表现、并发症及处理
Pub Date : 2022-08-30 DOI: 10.15406/ipcb.2022.08.00266
Gudisa Bereda
Chickenpox can be defined as a highly communicable viral infection caused by varicella zoster virus; most frequently influences pediatric in five to nine yrs old. The commonly occurred signs and symptoms of chickenpox are comprises vesicular rash appears on the scalp, face and trunk, and then disseminates distally to limbs (centrifugal distribution). The most common complications of chickenpox are bacterial soft-tissue infection, pneumonia, and encephalitis. Encephalitis is a most commonly occurred central nervous system complications expose the pediatric to other problems or death. The main goal chickenpox infection management in children is to alleviate the symptoms such as skin infections, fever, itching etc and making the children confortable. Adequate intravenous acyclovir administration is crucial for successful management of chickenpox, but it must be administered within twenty-four hrs. after the onset of the disease. Management of chickenpox with oral acyclovir given within twenty four hrs of onset of rash may be more effective.
水痘可定义为由水痘带状疱疹病毒引起的高度传染性病毒感染;最常影响儿童在5至9岁。水痘最常见的体征和症状包括在头皮、面部和躯干出现水疱疹,然后向远端扩散到四肢(离心分布)。水痘最常见的并发症是细菌性软组织感染、肺炎和脑炎。脑炎是一种最常发生的中枢神经系统并发症,使小儿暴露于其他问题或死亡。儿童水痘感染管理的主要目标是减轻皮肤感染、发热、瘙痒等症状,使儿童感到舒适。充分的静脉注射阿昔洛韦对成功治疗水痘至关重要,但必须在24小时内给药。在疾病发作后。在出现皮疹后24小时内口服阿昔洛韦治疗水痘可能更有效。
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引用次数: 0
期刊
International Journal of Pregnancy &amp; Child Birth
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