Pub Date : 2025-04-01DOI: 10.1016/j.rce.2025.01.002
N. Ramírez-Perea , D. Orozco-Beltrán
{"title":"Presente y futuro de los médicos internistas en la sanidad pública española","authors":"N. Ramírez-Perea , D. Orozco-Beltrán","doi":"10.1016/j.rce.2025.01.002","DOIUrl":"10.1016/j.rce.2025.01.002","url":null,"abstract":"","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 4","pages":"Pages 250-251"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rce.2024.10.011
J. Carretero Gómez , M.M. Chimeno Viñas , J.M. Porcel Pérez , M. Méndez Bailón , P. Pérez Martínez , M.T. Herranz Marín , N. del Prado , F.J. Elola Somoza
Objectives
To analyse the structure, activity and results of the internal medicine units (IMUs) of the Spanish National Health System (SNHS). To compare the results of the RECALMIN 2023 survey with previous waves of surveys of the UMIs (2008, 2015, 2017, 2019, 2021) and to analyse trends in the structure, activity and results of the UMIs.
Material and methods
There were 2 data sources: 1) survey on UMI structure and activity, and 2) hospital discharges of UMIs from the Minimum and Basic Data Set (CMBD) of the SNHS. Cross-sectional descriptive study of the UMIs in acute hospitals of the SNHS with data referring to 2022, comparing them with previous studies.
Results
Over the period 2007-2022, the rate of internists per 100,000 inhabitants increased (incidence rate ratio [IRR]: 4.5%; p < 0.001). Inpatient discharges per population and the number of discharges by UMI (IRR: 2.6%, p = 0.005; IRR: 3.5%, p < 0.001, respectively) also increased. The UMIs account for 20% of discharges from general hospitals in the NHS. The Internal Medicine Spanish Society has a database of the CMBD_MIN 2007-2022 with 9,931,401 discharges given by the UMI. The crude in-hospital hospital mortality rate increased in the period 2007-2022 (p < 0.001). From 2020 onwards (SARS-CoV-2 pandemic) overall risk-adjusted and process-adjusted mortality increased (p < 0.001).
Conclusions
UMIs have a central position in SNHS hospital care. The activity of the UMI has grown significantly in the period analysed. The RECALMIN project identifies strengths and opportunities to be strategically addressed by Internal Medicine Spanish Society.
{"title":"RECALMIN V. Evolución de la actividad de las unidades de medicina interna del Sistema Nacional de Salud (2007-2022)","authors":"J. Carretero Gómez , M.M. Chimeno Viñas , J.M. Porcel Pérez , M. Méndez Bailón , P. Pérez Martínez , M.T. Herranz Marín , N. del Prado , F.J. Elola Somoza","doi":"10.1016/j.rce.2024.10.011","DOIUrl":"10.1016/j.rce.2024.10.011","url":null,"abstract":"<div><h3>Objectives</h3><div>To analyse the structure, activity and results of the internal medicine units (IMUs) of the Spanish National Health System (SNHS). To compare the results of the RECALMIN 2023 survey with previous waves of surveys of the UMIs (2008, 2015, 2017, 2019, 2021) and to analyse trends in the structure, activity and results of the UMIs.</div></div><div><h3>Material and methods</h3><div>There were 2 data sources: 1) survey on UMI structure and activity, and 2) hospital discharges of UMIs from the Minimum and Basic Data Set (CMBD) of the SNHS. Cross-sectional descriptive study of the UMIs in acute hospitals of the SNHS with data referring to 2022, comparing them with previous studies.</div></div><div><h3>Results</h3><div>Over the period 2007-2022, the rate of internists per 100,000 inhabitants increased (incidence rate ratio [IRR]: 4.5%; p<!--> <!--><<!--> <!-->0.001). Inpatient discharges per population and the number of discharges by UMI (IRR: 2.6%, p<!--> <!-->=<!--> <!-->0.005; IRR: 3.5%, p<!--> <!--><<!--> <!-->0.001, respectively) also increased. The UMIs account for 20% of discharges from general hospitals in the NHS. The Internal Medicine Spanish Society has a database of the CMBD_MIN 2007-2022 with 9,931,401 discharges given by the UMI. The crude in-hospital hospital mortality rate increased in the period 2007-2022 (p < 0.001). From 2020 onwards (SARS-CoV-2 pandemic) overall risk-adjusted and process-adjusted mortality increased (p < 0.001).</div></div><div><h3>Conclusions</h3><div>UMIs have a central position in SNHS hospital care. The activity of the UMI has grown significantly in the period analysed. The RECALMIN project identifies strengths and opportunities to be strategically addressed by Internal Medicine Spanish Society.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 4","pages":"Pages 211-222"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rce.2024.11.002
S. Carrasco-Molina , Á. Robles-Marhuenda , J.J. Ríos-Blanco , Y. Tung-Chen
Acute confusional syndrome (ACS) is a disruption of cognitive function and attention that affects up to 42% of hospitalized patients, most commonly in those over the age of 65. It is typically triggered by one or more precipitating factors in predisposed patients. Point-of-care ultrasound (POCUS) emerges as a tool that could be used to provide quick and accurate information in the diagnosis of patients with ACS, potentially reducing the waiting time for critical interventions, decreasing the need for invasive procedures, and possibly improving clinical outcomes. To date, no articles have been published describing the utility of POCUS in patients with ACS.
Therefore, this work presents a review of the utility of POCUS in various pathologies that may be related to the development of ACS. Additionally, we propose an action algorithm that integrates clinical evaluation with bedside ultrasound, which could be useful for allowing quick and accurate identification of the underlying causes of ACS and the guidance of appropriate treatment, although prospective studies are needed to confirm this utility.
{"title":"Utilidad de la ecografía a pie de cama (POCUS) en el paciente hospitalizado con síndrome confusional agudo de etiología no aclarada","authors":"S. Carrasco-Molina , Á. Robles-Marhuenda , J.J. Ríos-Blanco , Y. Tung-Chen","doi":"10.1016/j.rce.2024.11.002","DOIUrl":"10.1016/j.rce.2024.11.002","url":null,"abstract":"<div><div>Acute confusional syndrome (ACS) is a disruption of cognitive function and attention that affects up to 42% of hospitalized patients, most commonly in those over the age of 65. It is typically triggered by one or more precipitating factors in predisposed patients. Point-of-care ultrasound (POCUS) emerges as a tool that could be used to provide quick and accurate information in the diagnosis of patients with ACS, potentially reducing the waiting time for critical interventions, decreasing the need for invasive procedures, and possibly improving clinical outcomes. To date, no articles have been published describing the utility of POCUS in patients with ACS.</div><div>Therefore, this work presents a review of the utility of POCUS in various pathologies that may be related to the development of ACS. Additionally, we propose an action algorithm that integrates clinical evaluation with bedside ultrasound, which could be useful for allowing quick and accurate identification of the underlying causes of ACS and the guidance of appropriate treatment, although prospective studies are needed to confirm this utility.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 4","pages":"Pages 231-239"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rce.2024.11.004
C. Font , P. Martínez de la Cruz , B. Herreros
Internists must respond to increasingly complex clinical scenarios in a context of progressively increasing life expectancy, techno-scientific development and accelerated demographic and sociocultural changes. Ethical reflection is a useful tool to resolve and prevent value conflicts, which are frequent in clinical practice. The ethical training of internists contributes to professional excellence and can be oriented at two complementary levels: 1) development of skills in all internists for the management of «clinical microethics», which allow the integration of the techno-scientific aspects of medicine in a satisfactory clinical relationship at a human level, and 2) specialization for internists who are experts in bioethics, to lead ethics committees (and other consulting models) in a more local setting and participate in bioethical debates and the development of normative ethics in a more general setting.
{"title":"La formación en ética clínica, una herramienta necesaria para la excelencia profesional del internista","authors":"C. Font , P. Martínez de la Cruz , B. Herreros","doi":"10.1016/j.rce.2024.11.004","DOIUrl":"10.1016/j.rce.2024.11.004","url":null,"abstract":"<div><div>Internists must respond to increasingly complex clinical scenarios in a context of progressively increasing life expectancy, techno-scientific development and accelerated demographic and sociocultural changes. Ethical reflection is a useful tool to resolve and prevent value conflicts, which are frequent in clinical practice. The ethical training of internists contributes to professional excellence and can be oriented at two complementary levels: 1)<!--> <!-->development of skills in all internists for the management of «clinical microethics», which allow the integration of the techno-scientific aspects of medicine in a satisfactory clinical relationship at a human level, and 2)<!--> <!-->specialization for internists who are experts in bioethics, to lead ethics committees (and other consulting models) in a more local setting and participate in bioethical debates and the development of normative ethics in a more general setting.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 4","pages":"Pages 244-249"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01DOI: 10.1016/j.rce.2024.07.011
E. Moya Mateo , R. García Alonso , C. Sánchez Sánchez , Y. Tung-Chen , E. Rodilla , L. Beltrán Romero , J.A. García-Donaire , M.V. Bonilla-Hernández , N. Muñoz-Rivas , L. Castilla-Guerra
Atherosclerosis is the disease which underlies the entire spectrum of atherosclerotic vascular disease. Point-of-care clinical ultrasound is a useful tool for its detection. Current guidelines recommend the use of scales such as SCORE2 (Systematic Coronary Risk Evaluation 2) and SCORE2-OP (Systematic Coronary risk Evaluation 2 Older Persons) for apparently healthy individuals and those at low-intermediate risk. The guidelines recognize the role of assessing the presence of plaques via ultrasound to refine risk stratification and optimize prevention strategies. However, the method of assessing the vascular territories where plaque is present and the amount or load of plaque is not homogeneous or well protocolized. In this document, two protocols are proposed for the evaluation of vascular risk: VASUS and VASUS+, which includes the presence of ventricular hypertrophy, with the aim of standardizing clinical ultrasound in the assessment of vascular risk in clinical practice.
{"title":"Posicionamiento para el uso de la ecografía clínica multivaso en la evaluación del riesgo vascular: protocolo VASUS+. Recomendaciones 2024 del grupo de riesgo vascular, ecografía clínica de la Sociedad Española de Medicina Interna y Sociedad Española de Hipertensión y Riesgo Vascular","authors":"E. Moya Mateo , R. García Alonso , C. Sánchez Sánchez , Y. Tung-Chen , E. Rodilla , L. Beltrán Romero , J.A. García-Donaire , M.V. Bonilla-Hernández , N. Muñoz-Rivas , L. Castilla-Guerra","doi":"10.1016/j.rce.2024.07.011","DOIUrl":"10.1016/j.rce.2024.07.011","url":null,"abstract":"<div><div>Atherosclerosis is the disease which underlies the entire spectrum of atherosclerotic vascular disease. Point-of-care clinical ultrasound is a useful tool for its detection. Current guidelines recommend the use of scales such as SCORE2 (Systematic Coronary Risk Evaluation 2) and SCORE2-OP (Systematic Coronary risk Evaluation 2 Older Persons) for apparently healthy individuals and those at low-intermediate risk. The guidelines recognize the role of assessing the presence of plaques via ultrasound to refine risk stratification and optimize prevention strategies. However, the method of assessing the vascular territories where plaque is present and the amount or load of plaque is not homogeneous or well protocolized. In this document, two protocols are proposed for the evaluation of vascular risk: VASUS and VASUS+, which includes the presence of ventricular hypertrophy, with the aim of standardizing clinical ultrasound in the assessment of vascular risk in clinical practice.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 4","pages":"Pages 223-230"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-19DOI: 10.1016/j.rce.2024.10.007
A. Esteban-Fernández , M. Anguita-Sánchez , N. Rosillo , J.L. Bonilla-Palomas , J.L. Bernal Sobrino , N. del Prado , C. Fernández Pérez , L. Rodríguez Padial , F.J. Elola Somoza
Introduction and objectives
Cardiac amyloidosis (CA) is a prevalent yet underdiagnosed heart condition characterized by the abnormal accumulation of amyloid fibres, frequently resulting in heart failure (HF), particularly in older people. Despite advancements in non-invasive diagnostic techniques and treatments, the epidemiology of CA patients remains inadequately understood. This nationwide retrospective observational study sought to comprehensively investigate CA patients’ characteristics, mortality, and readmission patterns.
Methods
A retrospective observational study encompassed all patients hospitalized with CA between 2016 and 2021 across Spanish hospitals. Standardized incidence rates were calculated using age and sex-adjusted methods, utilizing the Spanish population as the reference. The investigation delved into demographic variables, comorbidities, mortality during the index episode, and 30 and 365-day readmissions for circulatory system diseases. Predictors of readmission were also examined.
Results
A total of 5,739 index episodes were identified, with CA being the primary cause of admission in 14.1% of cases. The mean age was 81.4 ± 9.9 years, predominantly males (70.3%). The age and sex-standardized hospital attendance rate was 3.90 admissions per 100,000 population (95% CI: 3.82-3.98), higher in males. Common comorbidities included HF (96.4%), atrial fibrillation (46.3%), and renal failure (44.4%). The mortality rate during the index episode was 11.7%, with cardiogenic shock (OR: 9.03; 95% CI: 4.22-19.32) and major psychiatric disorders (OR: 3.36; 95% CI: 1.42-7.94) identified as predictors.
Over the follow-up period, 13.1% were readmitted at 30 days and 36.6% at 365. Nephritis (IRR: 2.05; 95% CI: 1.42-2.96) and asthma (IRR: 1.52; 95% CI 1.11-2.07) were associated with increased 30-day readmissions, while renal failure (IRR: 1.43; 95% CI: 1.28-1.59) and chronic pulmonary disease (IRR: 1.40; 95% CI: 1.18-1.67) were linked to higher 365-day readmissions. Predictors of mortality risk in 365-day readmissions included advanced cancer (HR: 1.31; 95% CI: 1.00-1.71), cardiogenic shock in the index episode (HR: 2.72; 95% CI: 1.33-5.57), and a higher number of readmissions during that period (HR: 1.64; 95% CI: 1.56-1.73).
Conclusions
This study contributes valuable insights into the significant prevalence of CA, which is often overlooked and underestimated. Afflicting predominantly elderly males with concomitant HF and multiple comorbidities, CA poses a significant clinical challenge. The findings underscore the need for enhanced awareness, early detection, and a multidisciplinary approach to manage this complex cardiac condition.
{"title":"Análisis de las características clínicas y pronóstico de los pacientes con amiloidosis cardiaca ingresados en los hospitales españoles (2016-2021)","authors":"A. Esteban-Fernández , M. Anguita-Sánchez , N. Rosillo , J.L. Bonilla-Palomas , J.L. Bernal Sobrino , N. del Prado , C. Fernández Pérez , L. Rodríguez Padial , F.J. Elola Somoza","doi":"10.1016/j.rce.2024.10.007","DOIUrl":"10.1016/j.rce.2024.10.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Cardiac amyloidosis (CA) is a prevalent yet underdiagnosed heart condition characterized by the abnormal accumulation of amyloid fibres, frequently resulting in heart failure (HF), particularly in older people. Despite advancements in non-invasive diagnostic techniques and treatments, the epidemiology of CA patients remains inadequately understood. This nationwide retrospective observational study sought to comprehensively investigate CA patients’ characteristics, mortality, and readmission patterns.</div></div><div><h3>Methods</h3><div>A retrospective observational study encompassed all patients hospitalized with CA between 2016 and 2021 across Spanish hospitals. Standardized incidence rates were calculated using age and sex-adjusted methods, utilizing the Spanish population as the reference. The investigation delved into demographic variables, comorbidities, mortality during the index episode, and 30 and 365-day readmissions for circulatory system diseases. Predictors of readmission were also examined.</div></div><div><h3>Results</h3><div>A total of 5,739 index episodes were identified, with CA being the primary cause of admission in 14.1% of cases. The mean age was 81.4<!--> <!-->±<!--> <!-->9.9<!--> <!-->years, predominantly males (70.3%). The age and sex-standardized hospital attendance rate was 3.90 admissions per 100,000 population (95%<!--> <!-->CI: 3.82-3.98), higher in males. Common comorbidities included HF (96.4%), atrial fibrillation (46.3%), and renal failure (44.4%). The mortality rate during the index episode was 11.7%, with cardiogenic shock (OR: 9.03; 95%<!--> <!-->CI: 4.22-19.32) and major psychiatric disorders (OR: 3.36; 95%<!--> <!-->CI: 1.42-7.94) identified as predictors.</div><div>Over the follow-up period, 13.1% were readmitted at 30<!--> <!-->days and 36.6% at 365. Nephritis (IRR: 2.05; 95%<!--> <!-->CI: 1.42-2.96) and asthma (IRR: 1.52; 95%<!--> <!-->CI 1.11-2.07) were associated with increased 30-day readmissions, while renal failure (IRR: 1.43; 95%<!--> <!-->CI: 1.28-1.59) and chronic pulmonary disease (IRR: 1.40; 95%<!--> <!-->CI: 1.18-1.67) were linked to higher 365-day readmissions. Predictors of mortality risk in 365-day readmissions included advanced cancer (HR: 1.31; 95%<!--> <!-->CI: 1.00-1.71), cardiogenic shock in the index episode (HR: 2.72; 95%<!--> <!-->CI: 1.33-5.57), and a higher number of readmissions during that period (HR: 1.64; 95%<!--> <!-->CI: 1.56-1.73).</div></div><div><h3>Conclusions</h3><div>This study contributes valuable insights into the significant prevalence of CA, which is often overlooked and underestimated. Afflicting predominantly elderly males with concomitant HF and multiple comorbidities, CA poses a significant clinical challenge. The findings underscore the need for enhanced awareness, early detection, and a multidisciplinary approach to manage this complex cardiac condition.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 3","pages":"Pages 131-139"},"PeriodicalIF":2.3,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143479089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-07DOI: 10.1016/j.rce.2024.10.009
N. Rosillo , N. del Prado , P. Pérez , J.L. Bernal , I. Núñez-Gil , Á. Gamarra , L. Vilches , J. Salamanca , J. Elola , F. Alfonso
Background and objectives
Takotsubo syndrome (TTS) is an infrequent cause of acute coronary syndrome much better diagnosed in recent years. This study sought to assess the clinical profile of patients admitted with TTS in Spain and to elucidate potential regional differences in admissions and in-hospital mortality between the years 2008 and 2021.
Methods
Retrospective observational study of patients admitted to acute general hospitals of the Spanish National Health System with a main or secondary diagnosis of STT, using the minimum basic data set.
Results
A total of 12.952 hospitalization for TTS were identified. The number of hospital admissions increased exponentially from 210 in the year 2008 to 1,918 in 2021. Most patients (79.1%) were women and mean age was 72.0 ± 12,5 years (72.5 ± 12,2 in female; 69.9 ± 13,4 in men; P<.001). Associated comorbidities were frequent (44.9% arterial hypertension, 31.2% heart failure) and differed in men and women. Overall, crude in-hospital mortality was 7%. Notably, admission and in-hospital mortality rates, adjusted by age and gender, were different among the different autonomous communities.
Conclusions
TTS usually presents in elderly women with associated comorbidities and has a significant in-hospital mortality. Age and comorbidities differ between men and women. Relevant regional differences exist regarding admission and in-hospital mortality rates.
{"title":"Hospitalizaciones por el síndrome de Takotsubo en España. Datos del CMBD por comunidades autónomas (años 2008-2021)","authors":"N. Rosillo , N. del Prado , P. Pérez , J.L. Bernal , I. Núñez-Gil , Á. Gamarra , L. Vilches , J. Salamanca , J. Elola , F. Alfonso","doi":"10.1016/j.rce.2024.10.009","DOIUrl":"10.1016/j.rce.2024.10.009","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Takotsubo syndrome (TTS) is an infrequent cause of acute coronary syndrome much better diagnosed in recent years. This study sought to assess the clinical profile of patients admitted with TTS in Spain and to elucidate potential regional differences in admissions and in-hospital mortality between the years 2008 and 2021.</div></div><div><h3>Methods</h3><div>Retrospective observational study of patients admitted to acute general hospitals of the Spanish National Health System with a main or secondary diagnosis of STT, using the minimum basic data set.</div></div><div><h3>Results</h3><div>A total of 12.952 hospitalization for TTS were identified. The number of hospital admissions increased exponentially from 210 in the year 2008 to 1,918 in 2021. Most patients (79.1%) were women and mean age was 72.0<!--> <!-->±<!--> <!-->12,5 years (72.5<!--> <!-->±<!--> <!-->12,2 in female; 69.9<!--> <!-->±<!--> <!-->13,4 in men; <em>P</em><.001). Associated comorbidities were frequent (44.9% arterial hypertension, 31.2% heart failure) and differed in men and women. Overall, crude in-hospital mortality was 7%. Notably, admission and in-hospital mortality rates, adjusted by age and gender, were different among the different autonomous communities.</div></div><div><h3>Conclusions</h3><div>TTS usually presents in elderly women with associated comorbidities and has a significant in-hospital mortality. Age and comorbidities differ between men and women. Relevant regional differences exist regarding admission and in-hospital mortality rates.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 3","pages":"Pages 140-147"},"PeriodicalIF":2.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143479090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-06DOI: 10.1016/j.rce.2024.08.007
M.A. Fidalgo Fernández , O. Madridano Cobo , C. Sánchez del Hoyo , A. Rodríguez Iglesias , A.N. Muñoz-Rivas , M. Martín Asenjo
Pulmonary embolism (PE) is a disease with a rising incidence rate. This article presents the recommendations for the diagnosis and treatment of PE of the Thromboembolic Disease Group of the Spanish Society of Internal Medicine (SEMI). The main objective is to facilitate decision making to improve the diagnostic and therapeutic approach based on published evidence. The final justification of the document is to improve the comprehensive care of the patient with PE.
肺栓塞(PE)是一种发病率不断上升的疾病。本文介绍了西班牙内科医学会(SEMI)血栓栓塞性疾病小组对肺栓塞诊断和治疗的建议。其主要目的是促进决策制定,以便根据已发表的证据改进诊断和治疗方法。该文件的最终目的是改善对 PE 患者的综合治疗。
{"title":"Diagnóstico y tratamiento de la embolia pulmonar. Recomendaciones del Grupo de Enfermedad Tromboembólica de la Sociedad Española de Medicina Interna 2024","authors":"M.A. Fidalgo Fernández , O. Madridano Cobo , C. Sánchez del Hoyo , A. Rodríguez Iglesias , A.N. Muñoz-Rivas , M. Martín Asenjo","doi":"10.1016/j.rce.2024.08.007","DOIUrl":"10.1016/j.rce.2024.08.007","url":null,"abstract":"<div><div>Pulmonary embolism (PE) is a disease with a rising incidence rate. This article presents the recommendations for the diagnosis and treatment of PE of the Thromboembolic Disease Group of the Spanish Society of Internal Medicine (SEMI). The main objective is to facilitate decision making to improve the diagnostic and therapeutic approach based on published evidence. The final justification of the document is to improve the comprehensive care of the patient with PE.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 3","pages":"Pages 168-175"},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143479092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.rce.2024.09.004
J.M. Mostaza , L. García-Ortiz , M.A. Suárez Tembra , P. Talavera Calle , J. Chimeno García , V. Escolar Pérez , J.L. Díaz-Díaz , L. Manzano-Espinosa , A.L. Catapano , K.K. Ray , G. Díaz Moya , J. Pedro-Botet Montoya , en representación del grupo de investigadores de SANTORINI España
Introduction
There are very few studies evaluating lipid-lowering treatments (LLTs) and low-density lipoprotein-cholesterol (LDL-C) goal attainment after the release of the 2019 guidelines of the European Societies of Cardiology (ESC) and Atherosclerosis (EAS). This manuscript shows baseline data of the Spanish subset from SANTORINI study (namely SANTORINI Spain) on LDL-C goal attainment and use of LLTs in patients at high and very high cardiovascular risk.
Methods
SANTORINI was a multinational, prospective, observational study involving patients at high and very high cardiovascular risk from 14 European countries in primary care and specialized healthcare settings. Sociodemographic data, blood lipid levels, and lipid treatments from the 1018 Spanish participants, were separately analyzed and were put into perspective with the European cohort without Spanish participants.
Results
According to physicians, 295 (29.0%) subjects were classified as high, and 723 (71.0%) as very high cardiovascular risk. Overall, 26.5% attained risk-based LDL-C targets recommended by 2019 European guidelines, with 23.1% of patients at high cardiovascular risk and 27.9% at very high cardiovascular risk. High-intensity statin therapy in monotherapy was used in 21.8%, LLT combination therapy in 41.2%, and 10.7% were not receiving any LLT.
Conclusions
Baseline data from SANTORINI Spain population show that only about one-fourth of patients attain LDL-C targets recommended by the 2019 ESC/EAS guidelines in patients at high and very high risk. Despite their cardiovascular risk, patients appear to be not adequately treated, and high-intensity and combination LLT seem to be underused for cardiovascular disease prevention in the real-world setting. ClinicalTrials.gov Identifier: NCT04271280.
{"title":"Fracaso en la consecución de los objetivos de c-LDL e infrautilización de tratamientos hipolipemiantes en pacientes con riesgo cardiovascular alto y muy alto: subpoblación española del estudio europeo SANTORINI","authors":"J.M. Mostaza , L. García-Ortiz , M.A. Suárez Tembra , P. Talavera Calle , J. Chimeno García , V. Escolar Pérez , J.L. Díaz-Díaz , L. Manzano-Espinosa , A.L. Catapano , K.K. Ray , G. Díaz Moya , J. Pedro-Botet Montoya , en representación del grupo de investigadores de SANTORINI España","doi":"10.1016/j.rce.2024.09.004","DOIUrl":"10.1016/j.rce.2024.09.004","url":null,"abstract":"<div><h3>Introduction</h3><div>There are very few studies evaluating lipid-lowering treatments (LLTs) and low-density lipoprotein-cholesterol (LDL-C) goal attainment after the release of the 2019 guidelines of the European Societies of Cardiology (ESC) and Atherosclerosis (EAS). This manuscript shows baseline data of the Spanish subset from SANTORINI study (namely SANTORINI Spain) on LDL-C goal attainment and use of LLTs in patients at high and very high cardiovascular risk.</div></div><div><h3>Methods</h3><div>SANTORINI was a multinational, prospective, observational study involving patients at high and very high cardiovascular risk from 14 European countries in primary care and specialized healthcare settings. Sociodemographic data, blood lipid levels, and lipid treatments from the 1018 Spanish participants, were separately analyzed and were put into perspective with the European cohort without Spanish participants.</div></div><div><h3>Results</h3><div>According to physicians, 295 (29.0%) subjects were classified as high, and 723 (71.0%) as very high cardiovascular risk. Overall, 26.5% attained risk-based LDL-C targets recommended by 2019 European guidelines, with 23.1% of patients at high cardiovascular risk and 27.9% at very high cardiovascular risk. High-intensity statin therapy in monotherapy was used in 21.8%, LLT combination therapy in 41.2%, and 10.7% were not receiving any LLT.</div></div><div><h3>Conclusions</h3><div>Baseline data from SANTORINI Spain population show that only about one-fourth of patients attain LDL-C targets recommended by the 2019 ESC/EAS guidelines in patients at high and very high risk. Despite their cardiovascular risk, patients appear to be not adequately treated, and high-intensity and combination LLT seem to be underused for cardiovascular disease prevention in the real-world setting. ClinicalTrials.gov Identifier: <span><span>NCT04271280</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 2","pages":"Pages 78-84"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143137448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.rce.2024.09.005
J. Carretero Gómez , T.F. Galeano Fernández , A.S. Vidal Ríos , S. Tolosa Álvarez , M. Sánchez Herrera , C. García Carrasco , F.J. Monreal Periañez , P. González González , J.C. Arévalo Lorido
Objective
This work aims to describe nutrition and sarcopenia in inpatients with heart failure (HF). It also aims to assess factors associated with in-hospital and short-term prognosis related to nutrition and sarcopenia.
Methods
We collected data on consecutive HF patients admitted to a single center's internal medicine ward. Patients were recruited in May and October 2021. Malnutrition was determined by the Mini Nutritional Assessment-Short Form (MNA-SF) and sarcopenia by the screening test, SARC-F scale, and handgrip strength test.
Results
190 patients were analyzed, mean age 82.1 (± 8.2), 54.2% women, median follow up 106 days. Patients were classified into three groups based on MNA-SF score: group 1 (12-14 points, no risk) included 50 patients, group 2 (8-12 points, high risk of malnutrition) included 81 patients, group 3 (0-7 points, malnourished) included 59 patients. Group 3 had significantly more inflammation (lower albumin and higher C-reactive Protein (CRP)) and congestion (mea-sured by NT-ProBNP levels). In-hospital mortality was related to poor muscle function, CRP, andNT-ProBNP, but not to malnutrition. The poorest short-term outcomes were related to malnutrition and comorbidity. However, when the variable of muscle function was introduced, it could act as a poor prognostic factor related to CRP and NT-ProBNP, which were the main determinantsof survival.
Conclusion
In malnourished patients with HF, inflammation and congestion were related to in-hospital mortality. Malnutrition along with comorbidity may play a role in decreasing short-term survival. Early identification through proactive nutritional and functional screenings should be a key element of assessing HF patients.
{"title":"La desnutrición en la insuficiencia cardíaca. La importancia de evaluar la congestión y la sarcopenia","authors":"J. Carretero Gómez , T.F. Galeano Fernández , A.S. Vidal Ríos , S. Tolosa Álvarez , M. Sánchez Herrera , C. García Carrasco , F.J. Monreal Periañez , P. González González , J.C. Arévalo Lorido","doi":"10.1016/j.rce.2024.09.005","DOIUrl":"10.1016/j.rce.2024.09.005","url":null,"abstract":"<div><h3>Objective</h3><div>This work aims to describe nutrition and sarcopenia in inpatients with heart failure (HF). It also aims to assess factors associated with in-hospital and short-term prognosis related to nutrition and sarcopenia.</div></div><div><h3>Methods</h3><div>We collected data on consecutive HF patients admitted to a single center's internal medicine ward. Patients were recruited in May and October 2021. Malnutrition was determined by the Mini Nutritional Assessment-Short Form (MNA-SF) and sarcopenia by the screening test, SARC-F scale, and handgrip strength test.</div></div><div><h3>Results</h3><div>190 patients were analyzed, mean age 82.1 (±<!--> <!-->8.2), 54.2% women, median follow up 106 days. Patients were classified into three groups based on MNA-SF score: group 1 (12-14 points, no risk) included 50 patients, group 2 (8-12 points, high risk of malnutrition) included 81 patients, group 3 (0-7 points, malnourished) included 59 patients. Group 3 had significantly more inflammation (lower albumin and higher C-reactive Protein (CRP)) and congestion (mea-sured by NT-ProBNP levels). In-hospital mortality was related to poor muscle function, CRP, andNT-ProBNP, but not to malnutrition. The poorest short-term outcomes were related to malnutrition and comorbidity. However, when the variable of muscle function was introduced, it could act as a poor prognostic factor related to CRP and NT-ProBNP, which were the main determinantsof survival.</div></div><div><h3>Conclusion</h3><div>In malnourished patients with HF, inflammation and congestion were related to in-hospital mortality. Malnutrition along with comorbidity may play a role in decreasing short-term survival. Early identification through proactive nutritional and functional screenings should be a key element of assessing HF patients.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"225 2","pages":"Pages 92-100"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143137918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}