Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.279
S. S. Lee, J. Chang, J. Seo
Purpose: The aim of this study was to determine the prevalence, types of variants, and clinical significance of mutations in precore, core promoter, and “a” determinant mutations in children with chronic hepatitis B virus infection. Methods: Thirty-one patients with chronic hepatitis B virus infection who visited Seoul National University Children's Hospital in Korea between 2004 and 2005 were enrolled in this study. Serum HBV DNA was amplified by polymerase chain reaction (PCR) and the precore/core promoter and “a” determinant sequences were determined. Results: Precore mutations were found in 11 of 27 patients (40.7%), and appeared more frequently in the HBeAg-negative group (p＜0.05) compared to the HBeAg-positive group. G1896A was detected most frequently (81.8%). BCP mutations were found in 15 of 27 patients (55.6%) and the TA mutation (A1762T/G1764A) was the most common (86.7%). Mutations in the “a” determinant region were detected in 8 of 28 patients (28.6%), and amino acid changes were detected in 6 of 28 patients (21.4%). Of these mutations, substitutions at amino acid position 126 were found most frequently. Conclusion: In children with chronic hepatitis B virus infection, the most common mutations were G1896A in the precore region and TA mutation(A1762T/G1764A) in the core promoter region. Substitutions at amino acid position 126 was the most common mutation in the “a” determinant. Precore mutants were found to be significantly higher in HBeAg-negative patients. The high prevalence of mutations in the “a” determinant and low frequency of G145R were characteristic features. These mutations were not significantly associated with other clinical features except for high aminotransferase concentration in the core promoter variant group. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 279∼285)
{"title":"Mutations in Hepatitis B Virus Precore, Core Promoter, and \"a\" Determinant in Children with Chronic Hepatitis B Virus Infection","authors":"S. S. Lee, J. Chang, J. Seo","doi":"10.5223/KJPGN.2011.14.3.279","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.279","url":null,"abstract":"Purpose: The aim of this study was to determine the prevalence, types of variants, and clinical significance of mutations in precore, core promoter, and “a” determinant mutations in children with chronic hepatitis B virus infection. Methods: Thirty-one patients with chronic hepatitis B virus infection who visited Seoul National University Children's Hospital in Korea between 2004 and 2005 were enrolled in this study. Serum HBV DNA was amplified by polymerase chain reaction (PCR) and the precore/core promoter and “a” determinant sequences were determined. Results: Precore mutations were found in 11 of 27 patients (40.7%), and appeared more frequently in the HBeAg-negative group (p＜0.05) compared to the HBeAg-positive group. G1896A was detected most frequently (81.8%). BCP mutations were found in 15 of 27 patients (55.6%) and the TA mutation (A1762T/G1764A) was the most common (86.7%). Mutations in the “a” determinant region were detected in 8 of 28 patients (28.6%), and amino acid changes were detected in 6 of 28 patients (21.4%). Of these mutations, substitutions at amino acid position 126 were found most frequently. Conclusion: In children with chronic hepatitis B virus infection, the most common mutations were G1896A in the precore region and TA mutation(A1762T/G1764A) in the core promoter region. Substitutions at amino acid position 126 was the most common mutation in the “a” determinant. Precore mutants were found to be significantly higher in HBeAg-negative patients. The high prevalence of mutations in the “a” determinant and low frequency of G145R were characteristic features. These mutations were not significantly associated with other clinical features except for high aminotransferase concentration in the core promoter variant group. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 279∼285)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134411903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.251
Ji Hyun Kang, Hae Jung Jung, J. K. Suh, Jun Seok Park, Hyo Jung Park, M. Chu, S. Cho, B. Choe
Purpose: This study evaluated the efficiency and safety of the Foley catheter for esophageal removal of coins in children, compared to standard endoscopic extraction with respect to success rate, sedation, promptness and cost. Methods: Twenty four children with coin lodgement in esophagus were managed with either a Foley catheter (n=14) or endoscopic extraction (n=10) from January 2007 through August 2010 at Kyungpook National University Hospital. A retrospective review of medical records and radiological findings was performed. Results: Of the 14 patients who underwent Foley catheter extraction, successful and complication-free removal was achieved in 10 cases (71.4%). Of the 10 patients who underwent endoscopic extraction, all cases were successful (p=0.114). Sedation rate in the Foley catheter and endoscopic extraction group was 6/14 and 10/10 (p=0.006). The average wait time before the procedure and average hospital charge (US$) were 2.0±1.1 hours and 18.1±13.7 hours, and $113 and $428 for Foley catheter extraction and endoscopic extraction, respectively. Conclusion: Foley catheter extraction may be tried for the removal of esophageal coins in uncomplicated children. The technique is effective, safe, inexpensive and free of general anesthesia. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 251∼257)
{"title":"Feasibility of Foley Catheter Prior to Endoscopy for the Removal of Esophageal Coin in Children","authors":"Ji Hyun Kang, Hae Jung Jung, J. K. Suh, Jun Seok Park, Hyo Jung Park, M. Chu, S. Cho, B. Choe","doi":"10.5223/KJPGN.2011.14.3.251","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.251","url":null,"abstract":"Purpose: This study evaluated the efficiency and safety of the Foley catheter for esophageal removal of coins in children, compared to standard endoscopic extraction with respect to success rate, sedation, promptness and cost. Methods: Twenty four children with coin lodgement in esophagus were managed with either a Foley catheter (n=14) or endoscopic extraction (n=10) from January 2007 through August 2010 at Kyungpook National University Hospital. A retrospective review of medical records and radiological findings was performed. Results: Of the 14 patients who underwent Foley catheter extraction, successful and complication-free removal was achieved in 10 cases (71.4%). Of the 10 patients who underwent endoscopic extraction, all cases were successful (p=0.114). Sedation rate in the Foley catheter and endoscopic extraction group was 6/14 and 10/10 (p=0.006). The average wait time before the procedure and average hospital charge (US$) were 2.0±1.1 hours and 18.1±13.7 hours, and $113 and $428 for Foley catheter extraction and endoscopic extraction, respectively. Conclusion: Foley catheter extraction may be tried for the removal of esophageal coins in uncomplicated children. The technique is effective, safe, inexpensive and free of general anesthesia. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 251∼257)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122971945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.222
H. Koh
Functional abdominal pain (FAP) is one of the most common pain syndromes in childhood and is a functional gastrointestinal disorder (FGID). Recurrent abdominal pain (RAP) is characterized by three or more episodes of abdominal pain that occurover at least 3 months and are severe enough to interfere with activities. It may be caused by many conditions, including inflammatory bowel disease, peptic ulcer, pancreatitis or, functional abdominal pain. The most common clinical manifestation is periumbilical pain related to autonomic and functional symptoms like nausea, vomiting, pallor and other painful conditions like headache and limb pains. RAP requires accurate diagnostic tests to rule out organic causes of pain based on ‘red flag’ sign. Furthermore, to diagnose and classify functional abdominal pain, Rome III criteria were published and updated with multiple discussions of FGIDs. Conventional interventions for RAP include reassurance and general advice, symptom-based pharmacological therapies, and psychological and behavioral treatments. But further research should be conducted to advance our understanding of the multiple factors involved in the pathogenesis of this group of conditions and to provide evidence for its therapeutic benefit. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 222∼231)
{"title":"Functional Abdominal Pain in Children","authors":"H. Koh","doi":"10.5223/KJPGN.2011.14.3.222","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.222","url":null,"abstract":"Functional abdominal pain (FAP) is one of the most common pain syndromes in childhood and is a functional gastrointestinal disorder (FGID). Recurrent abdominal pain (RAP) is characterized by three or more episodes of abdominal pain that occurover at least 3 months and are severe enough to interfere with activities. It may be caused by many conditions, including inflammatory bowel disease, peptic ulcer, pancreatitis or, functional abdominal pain. The most common clinical manifestation is periumbilical pain related to autonomic and functional symptoms like nausea, vomiting, pallor and other painful conditions like headache and limb pains. RAP requires accurate diagnostic tests to rule out organic causes of pain based on ‘red flag’ sign. Furthermore, to diagnose and classify functional abdominal pain, Rome III criteria were published and updated with multiple discussions of FGIDs. Conventional interventions for RAP include reassurance and general advice, symptom-based pharmacological therapies, and psychological and behavioral treatments. But further research should be conducted to advance our understanding of the multiple factors involved in the pathogenesis of this group of conditions and to provide evidence for its therapeutic benefit. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 222∼231)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130381303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.269
M. Cho, S. M. Song, S. Oh, Y. Lee, Jungin Jang, K. Kim
Purpose: The aim of this study was to investigate the existence of TNF-α polymorphisms in Korean children with Crohn’s disease (CD), ulcerative colitis (UC), as compared to healthy controls. Methods: Blood samples were obtained from 40 patients with CD, 14 patients with UC, and 30 healthy controls. Genotyping for 5 TNF-α polymorphisms (G238A, G308A, C857T, C863A, and T1031C) was performed. The allele frequencies for the inflammatory bowel diseases, CD and UC, were measured in patients with these disease and in healthy controls, and these allele frequencies were compared between the 3 groups. We examined the significant association between polymorphism and disease phenotype, such as location, behavior, perianal disease, and pediatric Crohn’s activity index (PCDAI) in CD. Results: Based on our findings, the TNF-α allele frequencies of G238A, G308A, C857T, C863A, and T1031C were 3.3, 8.3, 16.7, 16.7, 21.7% in healthy control, 2.5%, 7.5%, 18.8%, 20.0%, 22.5% in CD, 7.1%, 7.1%, 7.1%, 21.4%, 28.6% in UC. They were no statistically significant differences between the 3 groups. There were no associations between genotypes and phenotypes in CD, except a statistically significant higher allele frequency of G238A in ileal type (L1) disease (p=0.010). Conclusion: Our results indicate that 5 TNF-α polymorphisms do not seem to be associated with susceptibility to inflammatory bowel disease in Korean pediatric patients even though young patients were anticipated to have a stronger genetic affiliation for these diseases than adult patients. We think that further studies are needed to find those genes associated with susceptibility to CD and UC in Korean pediatric patients with inflammatory bowel disease. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 269∼278)
{"title":"Tumor Necrosis Factor-α Gene Polymorphisms in Korean Children with Inflammatory Bowel Disease","authors":"M. Cho, S. M. Song, S. Oh, Y. Lee, Jungin Jang, K. Kim","doi":"10.5223/KJPGN.2011.14.3.269","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.269","url":null,"abstract":"Purpose: The aim of this study was to investigate the existence of TNF-α polymorphisms in Korean children with Crohn’s disease (CD), ulcerative colitis (UC), as compared to healthy controls. Methods: Blood samples were obtained from 40 patients with CD, 14 patients with UC, and 30 healthy controls. Genotyping for 5 TNF-α polymorphisms (G238A, G308A, C857T, C863A, and T1031C) was performed. The allele frequencies for the inflammatory bowel diseases, CD and UC, were measured in patients with these disease and in healthy controls, and these allele frequencies were compared between the 3 groups. We examined the significant association between polymorphism and disease phenotype, such as location, behavior, perianal disease, and pediatric Crohn’s activity index (PCDAI) in CD. Results: Based on our findings, the TNF-α allele frequencies of G238A, G308A, C857T, C863A, and T1031C were 3.3, 8.3, 16.7, 16.7, 21.7% in healthy control, 2.5%, 7.5%, 18.8%, 20.0%, 22.5% in CD, 7.1%, 7.1%, 7.1%, 21.4%, 28.6% in UC. They were no statistically significant differences between the 3 groups. There were no associations between genotypes and phenotypes in CD, except a statistically significant higher allele frequency of G238A in ileal type (L1) disease (p=0.010). Conclusion: Our results indicate that 5 TNF-α polymorphisms do not seem to be associated with susceptibility to inflammatory bowel disease in Korean pediatric patients even though young patients were anticipated to have a stronger genetic affiliation for these diseases than adult patients. We think that further studies are needed to find those genes associated with susceptibility to CD and UC in Korean pediatric patients with inflammatory bowel disease. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 269∼278)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115624017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.286
N. Yang, H. Kim, M. K. Kim
multicultural family educational support center (8%), mass media (4%), and hospitals (3%). The cases of complementary food introduction after 8 months (21% vs. 10%, p＜0.001), initial use of commercial food (26% vs. 6%, P＜0.001) and initial use of bottle feeding (15% vs. 3%, p＜0.001) were more frequent compared to the 2009 Korean survey. Mothers agreeing with the following suggestions were relatively fewer: feeding minced meat from 6∼7 months (61%), No mixed cereal powder as complementary food (61%), feeding egg white after 12 months (63%), no adding salt or sugar to the complementary food (64%), bottle weaning before 15∼18 months (66%) and considering formula better than soy milk (68%). Conclusion: Complementary feeding practices of multicultural families showed many points of improvement compared with the 2009 Korean survey. Pediatricians should make more of an effort to consult with families of multicultural infants about nutrition and complementary feeding. Also, the government and the pediatrics academy need to institute policies to support the nutrition of multicultural infants. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 286∼298)
{"title":"Current Complementary Feeding and Maternal Nutritional Knowledge in Multicultural Family: Compared to the Korean Survey","authors":"N. Yang, H. Kim, M. K. Kim","doi":"10.5223/KJPGN.2011.14.3.286","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.286","url":null,"abstract":"multicultural family educational support center (8%), mass media (4%), and hospitals (3%). The cases of complementary food introduction after 8 months (21% vs. 10%, p＜0.001), initial use of commercial food (26% vs. 6%, P＜0.001) and initial use of bottle feeding (15% vs. 3%, p＜0.001) were more frequent compared to the 2009 Korean survey. Mothers agreeing with the following suggestions were relatively fewer: feeding minced meat from 6∼7 months (61%), No mixed cereal powder as complementary food (61%), feeding egg white after 12 months (63%), no adding salt or sugar to the complementary food (64%), bottle weaning before 15∼18 months (66%) and considering formula better than soy milk (68%). Conclusion: Complementary feeding practices of multicultural families showed many points of improvement compared with the 2009 Korean survey. Pediatricians should make more of an effort to consult with families of multicultural infants about nutrition and complementary feeding. Also, the government and the pediatrics academy need to institute policies to support the nutrition of multicultural infants. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 286∼298)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121142349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.299
Joo Whee Kim, M. Lim, S. C. Kim, Eun Hye Lee, J. Ko, J. Seo
With the increasing use of magnets in toys, magnet ingestion is becoming a serious problem in children. Two or more magnets may attract across the gastrointestinal tract leading to pressure necrosis, perforation, fistula, volvulus or obstruction. We report a case of a 12-year-old boy with autism who presented with vomiting during seven days due to ingestion of 14 magnetic rods. Under general anesthesia, 5 of 14 magnets were removed from the second portion of the duodenum using a magnetic probe during endoscopy. The remaining magnets were not visible in the duodenum. A plain radiograph taken the next day revealed that the remaining magnets were impacted in the descending-sigmoid junction. One magnet passed spontaneously. However the other 8 magnets did not pass through the junction for 7 days. Five of 8 impacted magnets were removed by a colonoscopic procedure. After 2 hours of colonoscopy, one by one, the remaining three magnets spontaneously passed. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 299∼304)
{"title":"A Case of Magnet Ingestion in a Child with Autism: Gastro-Colonoscopic Removal without Surgical Complication","authors":"Joo Whee Kim, M. Lim, S. C. Kim, Eun Hye Lee, J. Ko, J. Seo","doi":"10.5223/KJPGN.2011.14.3.299","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.299","url":null,"abstract":"With the increasing use of magnets in toys, magnet ingestion is becoming a serious problem in children. Two or more magnets may attract across the gastrointestinal tract leading to pressure necrosis, perforation, fistula, volvulus or obstruction. We report a case of a 12-year-old boy with autism who presented with vomiting during seven days due to ingestion of 14 magnetic rods. Under general anesthesia, 5 of 14 magnets were removed from the second portion of the duodenum using a magnetic probe during endoscopy. The remaining magnets were not visible in the duodenum. A plain radiograph taken the next day revealed that the remaining magnets were impacted in the descending-sigmoid junction. One magnet passed spontaneously. However the other 8 magnets did not pass through the junction for 7 days. Five of 8 impacted magnets were removed by a colonoscopic procedure. After 2 hours of colonoscopy, one by one, the remaining three magnets spontaneously passed. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 299∼304)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130684700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-09-01DOI: 10.5223/KJPGN.2011.14.3.245
J. Park
National University Hospital were reviewed. The main causes leading to ultrasonographic evaluation were abdominal pain (43.9%), vomiting (17.3%), elevated liver enzymes (11.8%), and jaundice (9.8%). Abnormal ultrasonographic findings accounted for 57.9% of cases. The major abnormal findings were mesenteric lymphadenitis (29.2%), fatty liver (12.1%), hepatitis (6.4%), hepatosplenomegaly (6.2%), and acute appendicitis (4.8%). The major findings in children with abdominal pain were mesenteric lymphadenitis (32.6%), intussusception (2.7%), and acute appendicitis (2.7%). The major findings in children with vomiting were mesenteric lymphadenitis (12.7%), hypertrophic pyloric stenosis (10.4%), acute appendicitis (3.5%). The major ultrasonographic findings in children with urinary tract diseases were hydronephrosis (45.4%), urolithiasis (21.5%) and cystic renal disease (18.1%). Ultrasonography performed by pediatricians is advantageous because pediatricians are able to perform the procedure with clinical information at the right time. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 245∼250)
{"title":"Usefulness and Pitfall of Abdominal Ultrasonographic Examination by a Pediatrician in Children","authors":"J. Park","doi":"10.5223/KJPGN.2011.14.3.245","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.245","url":null,"abstract":"National University Hospital were reviewed. The main causes leading to ultrasonographic evaluation were abdominal pain (43.9%), vomiting (17.3%), elevated liver enzymes (11.8%), and jaundice (9.8%). Abnormal ultrasonographic findings accounted for 57.9% of cases. The major abnormal findings were mesenteric lymphadenitis (29.2%), fatty liver (12.1%), hepatitis (6.4%), hepatosplenomegaly (6.2%), and acute appendicitis (4.8%). The major findings in children with abdominal pain were mesenteric lymphadenitis (32.6%), intussusception (2.7%), and acute appendicitis (2.7%). The major findings in children with vomiting were mesenteric lymphadenitis (12.7%), hypertrophic pyloric stenosis (10.4%), acute appendicitis (3.5%). The major ultrasonographic findings in children with urinary tract diseases were hydronephrosis (45.4%), urolithiasis (21.5%) and cystic renal disease (18.1%). Ultrasonography performed by pediatricians is advantageous because pediatricians are able to perform the procedure with clinical information at the right time. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 245∼250)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130999710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-06-01DOI: 10.5223/KJPGN.2011.14.2.161
Young-Ho Kim, Sun Gun Lee, Shin-Hye Kim, YoonJu Song, J. Chung, M. Park
목적: 한국 영유아의 영양 섭취 실태에 대한 연구가 매우 제한적으로 진행되고 있어, 본 연구에서는 국민건강영양조사를 이용하여 한국 유아들의 식이 행태, 식이보충제 및 영양소 섭취 실태를 알아보고자 하였다. 방법: 2007~2009년까지의 제4기 국민건강영양조사에 참여한 4세 미만의 영유아 930명(남 499명, 여 431명)을 대상으로 영아기의 식이 행태, 식이보충제 및 영양소 섭취 실태를 조사하였다. 결과: 식이보충제를 복용하는 유아는 48.7%로 절반가량이었으며 비타민/미네랄제가 35.3%로 제일 많았고 정장제 14.2%, 초유 8.2%였다. 식이보충제를 시작한 동기로는 95.4%가 친척이나 친구의 권유로, 0.7%가 자신의 판단으로 보충식을 시작했다고 답하였으며 의사의 권유로 보충제를 시작하는 비율은 0.3%에 불과하였다. 영양소 섭취 조사에서 유아의 51.6%는 탄수화물의 적정 비율을 섭취하고 있었고 32.7%가 적정 비율을 초과하여 섭취하고 있었다. 단백질의 경우 대상아의 94.8%가 적정 비율을 섭취하고 있었고, 지방의 경우 53.4%는 적정 비율을, 38.8%는 적정 비율 미만을 섭취하고 있었다. 칼슘을 평균필요량 미만으로 섭취하는 유아의 비율은 1세 53.9%, 2세 55.2%, 3세 65.6%, 철을 평균 필요량 미만으로 섭취하는 유아는 1세 52.0%, 2세 48.7%, 3세 48.4%였다. 영아기의 수유 패턴은 혼합 수유가 57.4%로 제일 많았고 32.2%가 모유 수유만, 10.4%가 분유 수유만을 하고 있었다. 이유식 도입시기는 4~6개월이 64.5%로 가장 많았고, 우유 도입시기는 12~17개월이 71.1%로 가장 많았다. 결론: 우리나라 만 1~만 3세 이하 유아의 절반가량이 의사의 상담 없이 식이보충제를 복용하고 있었으며, 칼슘, 철 섭취가 부족할 위험이 높았다. 이 시기의 영양관리를 위해 소아청소년과 의사를 비롯한 전문가의 역할이 보다 강조될 필요가 있다. 【Purpose: The aim of this study was to investigate the feeding patterns, use of dietary supplements, and nutrient intake of Korean toddlers. Methods: We used data for 930 toddlers who participated in the 4th Korean National Health and Nutrition Examination Survey (KNHANES) from 2007 to 2009. Feeding patterns and use of dietary supplements were assessed using standardized questionnaires, and nutrition intake was assessed using the 24 hr recall method. Results: In 2007~2009, 48.7% of toddlers used dietary supplements. Most parents (95.4%) initiated a regime of dietary supplements for their children following the advice of friends or relatives. Only 0.4% of parents followed the advice given by their doctors for dietary supplements use. In the survey of nutrient intake for toddlers, the prevalence of inadequate calcium intake was 53.9% for subjects aged 1 year, 55.2% for 2 years and 65.6% for subjects aged 3 years. The prevalence of inadequate iron intake was 52.0% for subjects aged 1 year, 48.7% for 2 years and 48.4% for subjects aged 3 years. In the survey performed on feeding patterns of toddlers during the infant period, mixed feeding accounted for 57.4%, breast feeding for 32.2%,and formula feeding for 10.4%. Sixty-five percent of toddlers began weaning between 4 and 6 months. Conclusions: This study indicated that a number of toddlers were at risk of inadequate calcium and iron intake. The role of professionals in counseling for qualified dietary intake and dietary supplement use is therefore necessary for Korean toddlers.】
目的:对韩国婴幼儿营养摄取实态的研究进行得非常有限，本研究想利用国民健康营养调查，了解韩国幼儿的饮食形态、饮食补充剂及营养素摄取实态。方法:2007~2009年第四期国民健康营养调查中，对930名未满4岁的婴幼儿(男499名，女431名)进行了婴儿期饮食形态，饮食补充剂及营养素摄取情况的调查。结果:服用膳食补充剂的幼儿占48.7%，占一半左右，维生素/矿物质以35.3%最多，正装剂占14.2%，初泡剂占8.2%。从饮食补充剂的动机来看，95.4%是在亲戚或朋友的劝说下开始的，0.7%是在自己的判断下开始的，在医生的劝说下开始补充剂的比率只有0.3%。在营养素摄取调查中，51.6%的幼儿摄取了碳水化合物的适当比率，32.7%摄取了超过适当比率的适当比率。蛋白质的情况是，94.8%的儿童摄取了适当的比率，脂肪的情况是53.4%摄取了适当的比率，38.8%摄取了不足适当比率。摄取钙的平均需要量不足的幼儿比率为，1岁53.9%、2岁55.2%、3岁65.6%、摄取铁的平均需要量不足的幼儿1岁52.0%、2岁48.7%、3岁48.4%。在婴儿期的哺乳模式中，混合哺乳最多，占57.4%，32.2%只进行母乳喂养，10.4%只进行奶粉喂养。从断奶食品引进时期来看，4~6个月最多，占64.5%;从牛奶引进时期来看，12~17个月最多，占71.1%。结论:韩国1~ 3岁以下幼儿的一半左右在没有医生咨询的情况下服用膳食补充剂，钙、铁摄取不足的危险较高。为了这一时期的营养管理，有必要更加强调少儿青少年科医生等专家的作用。The aim of this study was to investigate The feeding patterns, use of dietary supplements, and nutrient intake of Korean toddlers。Methods: We used data for 930 toddlers who participated in the第4届Korean National Health and Nutrition Examination Survey (KNHANES) from 2007 to 2009。Feeding patterns and use of dietary supplements were assessed using standardized questionnaires, and nutrition intake was assessed using the 24 hr recall method。Results: In 2007 - 2009, 48.7% of toddlers used dietary supplements。Most parents (95.4%) initiated a regime of dietary supplements for their children following the advice of friends or relatives。Only 0.4% of parents followed the advice given by their doctors for dietary supplements use。the survey of nutrient intake for toddlers, the prevalence of inadequate calcium intake was 53.9% for subjects aged 1年ar, 55.2% for 2年ars and 65.6% for subjects aged 3年ars。The prevalence of inadequate iron intake was 52.0% for subjects aged 1年ar, 48.7% for 2年ars and 48.4% for subjects aged 3年ars。In the survey performed on feeding patterns of toddlers during the infant period, mixed feeding accounted for 57.4%， breast feeding for 32.2%，and formula feeding for 10.4%。Sixty-five percent of toddlers began weaning between 4 and 6 months。Conclusions: This study indicated that a number of toddlers were at risk of inadequate calcium and iron intake。professionals in counseling for qualified dietary intake and dietary supplement use is therefore necessary for Korean toddlers。
{"title":"Nutritional Status of Korean Toddlers: From the Korean National Health and Nutrition Examination Survey 2007~2009","authors":"Young-Ho Kim, Sun Gun Lee, Shin-Hye Kim, YoonJu Song, J. Chung, M. Park","doi":"10.5223/KJPGN.2011.14.2.161","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.2.161","url":null,"abstract":"목적: 한국 영유아의 영양 섭취 실태에 대한 연구가 매우 제한적으로 진행되고 있어, 본 연구에서는 국민건강영양조사를 이용하여 한국 유아들의 식이 행태, 식이보충제 및 영양소 섭취 실태를 알아보고자 하였다. 방법: 2007~2009년까지의 제4기 국민건강영양조사에 참여한 4세 미만의 영유아 930명(남 499명, 여 431명)을 대상으로 영아기의 식이 행태, 식이보충제 및 영양소 섭취 실태를 조사하였다. 결과: 식이보충제를 복용하는 유아는 48.7%로 절반가량이었으며 비타민/미네랄제가 35.3%로 제일 많았고 정장제 14.2%, 초유 8.2%였다. 식이보충제를 시작한 동기로는 95.4%가 친척이나 친구의 권유로, 0.7%가 자신의 판단으로 보충식을 시작했다고 답하였으며 의사의 권유로 보충제를 시작하는 비율은 0.3%에 불과하였다. 영양소 섭취 조사에서 유아의 51.6%는 탄수화물의 적정 비율을 섭취하고 있었고 32.7%가 적정 비율을 초과하여 섭취하고 있었다. 단백질의 경우 대상아의 94.8%가 적정 비율을 섭취하고 있었고, 지방의 경우 53.4%는 적정 비율을, 38.8%는 적정 비율 미만을 섭취하고 있었다. 칼슘을 평균필요량 미만으로 섭취하는 유아의 비율은 1세 53.9%, 2세 55.2%, 3세 65.6%, 철을 평균 필요량 미만으로 섭취하는 유아는 1세 52.0%, 2세 48.7%, 3세 48.4%였다. 영아기의 수유 패턴은 혼합 수유가 57.4%로 제일 많았고 32.2%가 모유 수유만, 10.4%가 분유 수유만을 하고 있었다. 이유식 도입시기는 4~6개월이 64.5%로 가장 많았고, 우유 도입시기는 12~17개월이 71.1%로 가장 많았다. 결론: 우리나라 만 1~만 3세 이하 유아의 절반가량이 의사의 상담 없이 식이보충제를 복용하고 있었으며, 칼슘, 철 섭취가 부족할 위험이 높았다. 이 시기의 영양관리를 위해 소아청소년과 의사를 비롯한 전문가의 역할이 보다 강조될 필요가 있다. 【Purpose: The aim of this study was to investigate the feeding patterns, use of dietary supplements, and nutrient intake of Korean toddlers. Methods: We used data for 930 toddlers who participated in the 4th Korean National Health and Nutrition Examination Survey (KNHANES) from 2007 to 2009. Feeding patterns and use of dietary supplements were assessed using standardized questionnaires, and nutrition intake was assessed using the 24 hr recall method. Results: In 2007~2009, 48.7% of toddlers used dietary supplements. Most parents (95.4%) initiated a regime of dietary supplements for their children following the advice of friends or relatives. Only 0.4% of parents followed the advice given by their doctors for dietary supplements use. In the survey of nutrient intake for toddlers, the prevalence of inadequate calcium intake was 53.9% for subjects aged 1 year, 55.2% for 2 years and 65.6% for subjects aged 3 years. The prevalence of inadequate iron intake was 52.0% for subjects aged 1 year, 48.7% for 2 years and 48.4% for subjects aged 3 years. In the survey performed on feeding patterns of toddlers during the infant period, mixed feeding accounted for 57.4%, breast feeding for 32.2%,and formula feeding for 10.4%. Sixty-five percent of toddlers began weaning between 4 and 6 months. Conclusions: This study indicated that a number of toddlers were at risk of inadequate calcium and iron intake. The role of professionals in counseling for qualified dietary intake and dietary supplement use is therefore necessary for Korean toddlers.】","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125893905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-06-01DOI: 10.5223/KJPGN.2011.14.2.137
J. Moon
Research and development (R&D) is very important to acquire new knowledge in various fields. The significance of public R&D is also increasing, especially related to health policy making, establishing basic databases, and enhancing basic and clinical science. The total budget of general public R&D in Korea was approximately ten billon US Dollars in 2008, but the proportion of health care research was just below 10%. In private sectors, it was three times the amount allocated to the public budget. In this article, recent trends in public R&D in Korea, especially related to health care policy and biotechnology are summarized. A brief overview of the application process for a specific policy fund is also described for early-stage researchers in these fields. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 137∼140)
{"title":"Practical Aspects of Health Policy Research Themes in Korea","authors":"J. Moon","doi":"10.5223/KJPGN.2011.14.2.137","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.2.137","url":null,"abstract":"Research and development (R&D) is very important to acquire new knowledge in various fields. The significance of public R&D is also increasing, especially related to health policy making, establishing basic databases, and enhancing basic and clinical science. The total budget of general public R&D in Korea was approximately ten billon US Dollars in 2008, but the proportion of health care research was just below 10%. In private sectors, it was three times the amount allocated to the public budget. In this article, recent trends in public R&D in Korea, especially related to health care policy and biotechnology are summarized. A brief overview of the application process for a specific policy fund is also described for early-stage researchers in these fields. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 137∼140)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121431190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-06-01DOI: 10.5223/KJPGN.2011.14.2.155
J. We, Hyun Suk Park, J. Park
had no specific abnormal findings. Major causes of hematochezia were polyp (26.4%), food protein induced proctocolitis (6.9%), infectious colitis (5.4%), lymphofolliculitis (5.7%), non specific colitis (5.7%), and vascular ectasia (5. 1%). The hemorrhagic sites included the rectum (24.0%), rectosigmoid junction (18.1%), sigmoid colon (13.5%), ascending colon (14.2%), transverse colon (11.3%), descending colon (7.8%), cecum (8.1%), and terminal ileum (3.1%). The recurrence rate of hematochezia after colonoscopy was 19.1%. Colonoscopy was performed in 262 patients (94.6%) with conscious sedation. Endoscopic hemostasis was performed in 5 patients. Complications of colonoscopy or sedation were not found. Conclusion: The causes and lesional localization of pediatric hematochezia were diverse. Colonoscopy has an important role in the diagnosis and treatment of hematochezia in children. Total colonoscopy is recommended to detect the cause of hematochezia. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 155∼160)
{"title":"The Role of Colonoscopy in Children with Hematochezia","authors":"J. We, Hyun Suk Park, J. Park","doi":"10.5223/KJPGN.2011.14.2.155","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.2.155","url":null,"abstract":"had no specific abnormal findings. Major causes of hematochezia were polyp (26.4%), food protein induced proctocolitis (6.9%), infectious colitis (5.4%), lymphofolliculitis (5.7%), non specific colitis (5.7%), and vascular ectasia (5. 1%). The hemorrhagic sites included the rectum (24.0%), rectosigmoid junction (18.1%), sigmoid colon (13.5%), ascending colon (14.2%), transverse colon (11.3%), descending colon (7.8%), cecum (8.1%), and terminal ileum (3.1%). The recurrence rate of hematochezia after colonoscopy was 19.1%. Colonoscopy was performed in 262 patients (94.6%) with conscious sedation. Endoscopic hemostasis was performed in 5 patients. Complications of colonoscopy or sedation were not found. Conclusion: The causes and lesional localization of pediatric hematochezia were diverse. Colonoscopy has an important role in the diagnosis and treatment of hematochezia in children. Total colonoscopy is recommended to detect the cause of hematochezia. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 155∼160)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"118 1-2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120905026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：