Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666453
J. Tsuei
The acupuncture and meridian system of traditional Chinese medicine is an important, real biophysical aspect of the living body. With the electrodermal screening device (EDSD), it is possible to define, both quantitatively and qualitatively, much of the meridian system. The meridian system is essential to most or possibly all bodily functions, and the EDSD, which reads meridian information, is capable of delivering valuable information on nearly every facet of bodily function. The EDST could serve as the standard "ruler" by which biological energy is measured, similar to body temperature and blood pressure measurements. In other words, it is conceivable that someday the EDSD will be as commonplace as the thermometer and sphygmomanometer. The EDSD is non-invasive and economical. With further refinement and acceptance of the EDSD and the associated testing methodology (EDST) and health management system (EDSS), it will be possible to chart even the higher functions, including emotional, cognitive, and psychosomatic. The EDST has the potential of developing into a truly complete test of the body, making possible levels of international medical standardization and meta-analysis unknown today. The device, test, and system may prove to be the greatest set of tools against disease created this century. But now what is needed is much more research. It is the authors' sincere hope that many others in the medical-scientific community will see the EDST's potential and initiate further research projects.
{"title":"A modern interpretation of acupuncture and the meridian system","authors":"J. Tsuei","doi":"10.1109/ICBEM.1998.666453","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666453","url":null,"abstract":"The acupuncture and meridian system of traditional Chinese medicine is an important, real biophysical aspect of the living body. With the electrodermal screening device (EDSD), it is possible to define, both quantitatively and qualitatively, much of the meridian system. The meridian system is essential to most or possibly all bodily functions, and the EDSD, which reads meridian information, is capable of delivering valuable information on nearly every facet of bodily function. The EDST could serve as the standard \"ruler\" by which biological energy is measured, similar to body temperature and blood pressure measurements. In other words, it is conceivable that someday the EDSD will be as commonplace as the thermometer and sphygmomanometer. The EDSD is non-invasive and economical. With further refinement and acceptance of the EDSD and the associated testing methodology (EDST) and health management system (EDSS), it will be possible to chart even the higher functions, including emotional, cognitive, and psychosomatic. The EDST has the potential of developing into a truly complete test of the body, making possible levels of international medical standardization and meta-analysis unknown today. The device, test, and system may prove to be the greatest set of tools against disease created this century. But now what is needed is much more research. It is the authors' sincere hope that many others in the medical-scientific community will see the EDST's potential and initiate further research projects.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129851661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666408
John T. Rowlev, Rod, Waterhouse, Ken H. Joynerl
The Finite Difference Time Domain Technique (FDTD) has been favoured for numerical bioelectromagnetic analysis by a number of researchers because of the relative ease of modelling complex dielectric bodies. Antenna performance and specific absorption rate (SAR) results are presented at 1800 MHz for a half wavelength dipole, a monopole and a planar inverted F antenna in free space and in the presence of different head phantoms. The phantoms used were a homogeneous sphere, a layered sphere and a realistic head model all using a 2.5 mm cubic voxel grid. The trend in the SAR results confirms the observation of others that the simpler head phantoms tend to overestimate the maximum SAR in comparison to more realistic models.
{"title":"FDTD handset antenna modelling at 1800 MHz for electrical performance and SAR results","authors":"John T. Rowlev, Rod, Waterhouse, Ken H. Joynerl","doi":"10.1109/ICBEM.1998.666408","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666408","url":null,"abstract":"The Finite Difference Time Domain Technique (FDTD) has been favoured for numerical bioelectromagnetic analysis by a number of researchers because of the relative ease of modelling complex dielectric bodies. Antenna performance and specific absorption rate (SAR) results are presented at 1800 MHz for a half wavelength dipole, a monopole and a planar inverted F antenna in free space and in the presence of different head phantoms. The phantoms used were a homogeneous sphere, a layered sphere and a realistic head model all using a 2.5 mm cubic voxel grid. The trend in the SAR results confirms the observation of others that the simpler head phantoms tend to overestimate the maximum SAR in comparison to more realistic models.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125383165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666442
P. Fleischmann, P. Wach
A 3D cellular automata model of the entire heart was used for modelling the spread of excitation and repolarization in the heart. By modelling ventricular pacing and premature stimuli the inducibility of bundle branch re-entry was investigated. Under normal conditions bundle branch re-entry of type A and B were induced. A reduction of conduction velocity in the bundle branches resulted in multiple re-entrant echo beats as well as a wider zone of re-entrant activation.
{"title":"Computer simulation of bundle branch re-entry in a 3D cellular automata model of the heart","authors":"P. Fleischmann, P. Wach","doi":"10.1109/ICBEM.1998.666442","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666442","url":null,"abstract":"A 3D cellular automata model of the entire heart was used for modelling the spread of excitation and repolarization in the heart. By modelling ventricular pacing and premature stimuli the inducibility of bundle branch re-entry was investigated. Under normal conditions bundle branch re-entry of type A and B were induced. A reduction of conduction velocity in the bundle branches resulted in multiple re-entrant echo beats as well as a wider zone of re-entrant activation.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130177329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666380
G. McDarby, B. Celler, N. Lovell
The spectral distribution of energy varies between normal ECGs and those from patients post infarct or with ventricular hypertrophies. This suggests that discriminating between normal and abnormal conditions may be possible on the basis of differences in the distribution of spectral energy. The authors compare a reduced Discrete Wavelet Transform characterisation of an ECG QRS complex using three different wavelets. The wavelet transforms are based on dyadic scales and decompose the ECG signals into four detail levels and one approximation level with each decomposition being characterised by a mean and a standard deviation value. The authors' results indicate that, even after reducing the information in each level of decomposition of the wavelet transform to these two simple values, the discriminating power between normal and abnormal cases, calculated using receiver operator curve (ROC) analysis, exceeds 75%. This improves on the results obtained for scalar parameters such as QRS duration, areas and cardiac axis.
{"title":"Characterising the discrete wavelet transform of an ECG signal with simple parameters for use in automated diagnosis","authors":"G. McDarby, B. Celler, N. Lovell","doi":"10.1109/ICBEM.1998.666380","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666380","url":null,"abstract":"The spectral distribution of energy varies between normal ECGs and those from patients post infarct or with ventricular hypertrophies. This suggests that discriminating between normal and abnormal conditions may be possible on the basis of differences in the distribution of spectral energy. The authors compare a reduced Discrete Wavelet Transform characterisation of an ECG QRS complex using three different wavelets. The wavelet transforms are based on dyadic scales and decompose the ECG signals into four detail levels and one approximation level with each decomposition being characterised by a mean and a standard deviation value. The authors' results indicate that, even after reducing the information in each level of decomposition of the wavelet transform to these two simple values, the discriminating power between normal and abnormal cases, calculated using receiver operator curve (ROC) analysis, exceeds 75%. This improves on the results obtained for scalar parameters such as QRS duration, areas and cardiac axis.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121197097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666383
Q. Fang, Irena Cosic
The relationship between protein's amino acid sequence and its biological function remains an unsolved question in molecular biology. Using wavelet packet transform and the Resonant Recognition Model, it is possible to extract features characterising the electromagnetic properties of protein molecules. These features may improve the understanding of protein's structure and function relationship.
{"title":"Finding characteristic bands from protein sequences using wavelet packet transform and energy map","authors":"Q. Fang, Irena Cosic","doi":"10.1109/ICBEM.1998.666383","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666383","url":null,"abstract":"The relationship between protein's amino acid sequence and its biological function remains an unsolved question in molecular biology. Using wavelet packet transform and the Resonant Recognition Model, it is possible to extract features characterising the electromagnetic properties of protein molecules. These features may improve the understanding of protein's structure and function relationship.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116583666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666424
L.Y. Xu, Y. Zhang
The mean frequency of EMG and VMG signals has been used as an indicator for muscle fatigue. The muscle fatigue is a complex process, which involves both central nerve system (CNS) and local muscle activities. Here, the authors adopt a multichannel linear dynamic model for EMG and VMG signal generations under voluntary contractions. The mean frequency of EMG and VMG signals under the different firing statistics was calculated. The results show that the mean frequency of VMG signal is more sensitive to the mean firing rate of the innervation than that of corresponding EMG signal, suggesting that the VMG signal might be more sensitive to CNS fatigue.
{"title":"Effects of firing statistics on the mean frequency of EMG and VMG signals","authors":"L.Y. Xu, Y. Zhang","doi":"10.1109/ICBEM.1998.666424","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666424","url":null,"abstract":"The mean frequency of EMG and VMG signals has been used as an indicator for muscle fatigue. The muscle fatigue is a complex process, which involves both central nerve system (CNS) and local muscle activities. Here, the authors adopt a multichannel linear dynamic model for EMG and VMG signal generations under voluntary contractions. The mean frequency of EMG and VMG signals under the different firing statistics was calculated. The results show that the mean frequency of VMG signal is more sensitive to the mean firing rate of the innervation than that of corresponding EMG signal, suggesting that the VMG signal might be more sensitive to CNS fatigue.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"44 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122421449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666397
M. Zago, P. Fossati, A. Palombo, G. D'Inzeo
In this paper the authors develop a model to describe the interaction between an electromagnetic field and a biological microstructure (protoporphyrin M). The authors suppose that the energy transferred from the field to the molecule induces a change in the molecule's normal frequencies of vibration. They use a molecular dynamic simulation package to calculate the new vibrational frequencies when the field is applied. They use these new calculated frequencies as an input for a model that, considering linear coupling between these modes and an electronic transition, allows the authors to calculate the absorption spectrum in the Soret band.
{"title":"Reconstruction of the spectral properties of a biomolecule under electromagnetic exposure by means of molecular simulation","authors":"M. Zago, P. Fossati, A. Palombo, G. D'Inzeo","doi":"10.1109/ICBEM.1998.666397","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666397","url":null,"abstract":"In this paper the authors develop a model to describe the interaction between an electromagnetic field and a biological microstructure (protoporphyrin M). The authors suppose that the energy transferred from the field to the molecule induces a change in the molecule's normal frequencies of vibration. They use a molecular dynamic simulation package to calculate the new vibrational frequencies when the field is applied. They use these new calculated frequencies as an input for a model that, considering linear coupling between these modes and an electronic transition, allows the authors to calculate the absorption spectrum in the Soret band.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129284913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666414
I. Konkka, H. Eskola, V. Turjanmaa
Electrogastrography is a non-invasive method for obtaining information of electrical activity of the stomach. Due to non-invasiveness, it may be useful tool in routine diagnostic use, but because the nature of electrical activity of the stomach is not completely clear, it is not in everyday use. Electrical modeling may solve some unexplained questions. The authors present an electrical conductivity model, which takes into consideration the inhomogeneities of human body and anatomical shape of the stomach. Two three-dimensional models have been made, one based on the anatomical data of Visible Human, and other on CT images of a healthy subject. These models enable a more detailed analysis of the reflection of the effect of electrical activity of the stomach to the abdominal surface.
{"title":"Accurate conductivity model of the human abdomen for electrogastrography","authors":"I. Konkka, H. Eskola, V. Turjanmaa","doi":"10.1109/ICBEM.1998.666414","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666414","url":null,"abstract":"Electrogastrography is a non-invasive method for obtaining information of electrical activity of the stomach. Due to non-invasiveness, it may be useful tool in routine diagnostic use, but because the nature of electrical activity of the stomach is not completely clear, it is not in everyday use. Electrical modeling may solve some unexplained questions. The authors present an electrical conductivity model, which takes into consideration the inhomogeneities of human body and anatomical shape of the stomach. Two three-dimensional models have been made, one based on the anatomical data of Visible Human, and other on CT images of a healthy subject. These models enable a more detailed analysis of the reflection of the effect of electrical activity of the stomach to the abdominal surface.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130822358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666411
E. Lazoura, I. Cosic
The Resonant Recognition Model (RRM) has been applied to chymotrypsin to design peptides that exhibit chymotrypsin-like activity. Molecular modelling studies indicate that a 19-mer (chlida 2), which has a f/sub RRM/=0.2344 and /spl phi/=-1.186, folds appropriately so that the spatial separation of the amino acids required for chymotrypsin activity is comparable with that of /spl alpha/-chymotrypsin.
{"title":"RRM designed /spl alpha/-chymotrypsin-like peptides","authors":"E. Lazoura, I. Cosic","doi":"10.1109/ICBEM.1998.666411","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666411","url":null,"abstract":"The Resonant Recognition Model (RRM) has been applied to chymotrypsin to design peptides that exhibit chymotrypsin-like activity. Molecular modelling studies indicate that a 19-mer (chlida 2), which has a f/sub RRM/=0.2344 and /spl phi/=-1.186, folds appropriately so that the spatial separation of the amino acids required for chymotrypsin activity is comparable with that of /spl alpha/-chymotrypsin.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130981227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-02-15DOI: 10.1109/ICBEM.1998.666430
O. Okazaki, D. Wei, K. Harumi
This study is a three-dimensional (3-D) simulation aimed at verification about the M cell function during Torsade de Pointes (TdP). The entire process of TdP initiation, propagation and termination were successfully reproduced and the M cell function was examined. The heart model used in this simulation was previously described in detail (D. Wei et al., IEEE, vol. 42, p. 343-57, 1995). The model consists of approximately 50,000 functional cubic units with spatial resolution of 1.5 mm in dameter. Findings in the authors' study agree to those of C. Antzelevitch et al. (1996). By setting M cells in the heart model, the authors' study successfully simulated the TdP process and suggests that the reentry around M cells might be a possible mechanism in the formation of TdP.
本研究是一个三维(3-D)模拟，旨在验证M细胞在扭转角(TdP)期间的功能。成功复制了TdP起始、增殖和终止的整个过程，并检测了M细胞的功能。在此模拟中使用的心脏模型先前有详细描述(D. Wei et al.， IEEE, vol. 42, p. 343-57, 1995)。该模型由大约50,000个功能立方单元组成，空间分辨率为1.5 mm。作者的研究结果与C. Antzelevitch等人(1996)的研究结果一致。通过在心脏模型中设置M细胞，作者的研究成功地模拟了TdP过程，并提示M细胞周围的再进入可能是TdP形成的一种可能机制。
{"title":"Three dimensional excitation sequence during Torsade de Points in the cardiac computer model with M cells","authors":"O. Okazaki, D. Wei, K. Harumi","doi":"10.1109/ICBEM.1998.666430","DOIUrl":"https://doi.org/10.1109/ICBEM.1998.666430","url":null,"abstract":"This study is a three-dimensional (3-D) simulation aimed at verification about the M cell function during Torsade de Pointes (TdP). The entire process of TdP initiation, propagation and termination were successfully reproduced and the M cell function was examined. The heart model used in this simulation was previously described in detail (D. Wei et al., IEEE, vol. 42, p. 343-57, 1995). The model consists of approximately 50,000 functional cubic units with spatial resolution of 1.5 mm in dameter. Findings in the authors' study agree to those of C. Antzelevitch et al. (1996). By setting M cells in the heart model, the authors' study successfully simulated the TdP process and suggests that the reentry around M cells might be a possible mechanism in the formation of TdP.","PeriodicalId":213764,"journal":{"name":"Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269)","volume":"8 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120857033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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