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2019 12th Biomedical Engineering International Conference (BMEiCON)最新文献

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Automatic segmentation of polycystic kidneys from magnetic resonance images using decision tree classification and snake algorithm 基于决策树分类和蛇算法的磁共振图像多囊肾自动分割
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990257
Jamie A. O’Reilly, Sakuntala Tanpradit, T. Puttasakul, M. Sangworasil, T. Matsuura, P. Wibulpolprasert, Khaisang Chousangsuntorn
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive bilateral renal cyst formation, leading to severe increases in kidney volume and loss of function. Total kidney volume (TKV) is the only established biomarker for tracking ADPKD. This is measured multiple times per year from each patient to examine the extent of renal enlargement and overall cyst load. Currently this is conducted by planimetry tracing, which involves manually delineating kidneys from surrounding tissues in the abdominal cavity using a digital drawing tool. By performing this on every image in a magnetic resonance scan, TKV is estimated. This is a time-consuming and laborious process for radiologists. Our aim is to develop an automated method for ADPKD patient kidney segmentation and quantifying TKV. Thirteen MRI scans of kidneys ranging across the spectrum from normal to severe cyst load were analyzed. Images were separated into two halves, each made up of 200 square regions. Features were extracted from grayscale values of each region, and these data were combined in a supervised decision tree algorithm to classify between kidney and non-kidney regions. Filtering and dilation were applied to the classified 400x400 matrix in order to roughly segment the kidneys. Contrast enhancement and k-means clustering was performed before applying an active contour function to determine kidney edges. Eccentricity analysis confirmed appropriate relative sphericity for segmented kidney shapes, before combining their areas with linear extrapolation to estimate TKV. This protocol is evaluated against clinical reference standard TKV measurements.
常染色体显性多囊肾病(ADPKD)的特点是进行性双侧肾囊肿形成,导致肾脏体积严重增加和功能丧失。总肾容量(TKV)是唯一确定的跟踪ADPKD的生物标志物。每年对每位患者进行多次测量,以检查肾脏肿大的程度和总体囊肿负荷。目前,这是通过平面测量追踪进行的,这涉及到使用数字绘图工具从腹腔内的周围组织手动划定肾脏。通过对磁共振扫描中的每个图像执行此操作,可以估计TKV。这对放射科医生来说是一个费时费力的过程。我们的目标是开发一种自动化的方法,用于ADPKD患者肾脏分割和量化TKV。分析了从正常到严重囊肿负荷的13个肾脏MRI扫描。图像被分成两半,每半由200个正方形区域组成。从每个区域的灰度值中提取特征,并将这些数据结合在监督决策树算法中进行肾脏和非肾脏区域的分类。对分类后的400x400基质进行过滤和扩张,大致分割肾脏。在应用活动轮廓函数确定肾脏边缘之前,进行对比度增强和k-means聚类。在结合线性外推法估算TKV之前,离心分析确定了分段肾脏形状的适当相对球度。该方案根据临床参考标准TKV测量值进行评估。
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引用次数: 6
Electrical Modeling of Dynamical Interaction among Intracranial Pressure, Intraocular Pressure, Cerebral Perfusion Pressure, and Arterial Blood Pressure 颅内压、眼内压、脑灌注压和动脉压动态相互作用的电模型
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990274
K. Charoensuk, T. Sethaput, I. Nilkhamhang
In case study, the dynamical behavior of various systems including intracranial pressure (ICP), cerebral perfusion pressure (CPP), intraocular pressure (IOP), arterial blood pressure (ABP), and blood flow (BF) are studied based on the equivalent electrical model. The healthy people from clinical data are used for study those behaviors. Resistor-Capacitance network is constructed to simulate ICP inside the skull, IOP of the retinal vessel, CPP in the skull. Moreover, ABP from the heart (85 - 120 mmHg) and Intraspinal Pressure (ISP) (50 - 60 mmHg) are applied as inputs to this model. The results show the value of ICP of normal state, IOP, and CPP in the skull are 5-15 mmHg, 20-35 mmHg, and 65-90 mmHg respectively. For the phase relationship among ABP, CPP, IOP, and ICP are synchronized. The differential phase between ABP and BF is 0.25 to 0.5 second where ABP waveform was leaded BF waveform. Our model is verified by clinical data from noninvasive measuring method. This model provides a clear explanation of the interaction behavior between ICP, CCP, IOP, ABP and BF of healthy individuals.
在实例研究中,基于等效电模型研究了颅内压(ICP)、脑灌注压(CPP)、眼内压(IOP)、动脉压(ABP)和血流(BF)等系统的动力学行为。临床数据中的健康人群被用来研究这些行为。构建电阻-电容网络,模拟颅内压、视网膜血管内压、颅脑内压。此外,心脏ABP (85 - 120 mmHg)和椎内压(ISP) (50 - 60 mmHg)作为该模型的输入。结果显示,正常状态下颅内压为5 ~ 15mmhg,颅内压为20 ~ 35mmhg,颅内压为65 ~ 90mmhg。对于ABP的相位关系,CPP、IOP和ICP是同步的。ABP与BF之间的差相位为0.25 ~ 0.5秒,ABP波形超前于BF波形。通过无创测量的临床数据验证了模型的有效性。该模型清晰地解释了健康个体的ICP、CCP、IOP、ABP和BF之间的相互作用行为。
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引用次数: 2
Analyzing Motivational Components of Visual Cognitive Stimulus 视觉认知刺激的动机成分分析
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990317
Tustanah Phukhachee, S. Maneewongvatana, B. Kaewkamnerdpong
Intrinsic motivation is an internal brain state that leads us to increase the efforts and attention in pursuing the goal. This intrinsic motivation can emerge for self-satisfaction without any external reward. In the education system, knowing the factors that lead students to have intrinsic motivation is, therefore, crucial information in improving the efficiency of the learning process. There were some studies on emotional scenes that could influence the intrinsic motivation of participants. However, it could be hard to apply the complete scene to the teaching material. It would be better if we know the components which lead students to have intrinsic motivation and apply them to the teaching material. In this study, we analyzed the motivation components of visual cognitive stimuli from motivation-based cognitive data. The components were analyzed in terms of scene types (indoor/outdoor) and motivational objects that cause participants to have intrinsic motivation. It was found that participants were motivated to memorize the outdoor scenes than the indoor scenes (p < 0.01). Using decision tree, the relationship of the motivational object that lead participants to have intrinsic motivation are reported as the suggestion for applying to the visual teaching material in the future.
内在动机是一种内在的大脑状态,它引导我们在追求目标的过程中增加努力和注意力。这种内在动机可以在没有任何外部奖励的情况下产生自我满足。因此,在教育系统中,了解导致学生产生内在动机的因素是提高学习过程效率的关键信息。有一些关于情绪场景影响被试内在动机的研究。然而,很难将完整的场景应用到教材中。如果我们知道导致学生产生内在动机的因素,并将其应用到教材中,那就更好了。在本研究中,我们从基于动机的认知数据中分析视觉认知刺激的动机成分。根据场景类型(室内/室外)和引起参与者产生内在动机的动机对象来分析这些成分。结果发现,被试对室外场景记忆的积极性高于室内场景记忆(p < 0.01)。运用决策树分析了导致参与者产生内在动机的动机客体之间的关系,作为今后在视觉教材中应用的建议。
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引用次数: 0
[BMEiCON 2019 Title Page] [BMEiCON 2019标题页]
Pub Date : 2019-11-01 DOI: 10.1109/bmeicon47515.2019.8990281
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引用次数: 0
An Infant Cry Recognition based on Convolutional Neural Network Method 基于卷积神经网络的婴儿哭声识别方法
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990191
K. Teeravajanadet, N. Siwilai, K. Thanaselanggul, N. Ponsiricharoenphan, S. Tungjitkusolmun, P. Phasukkit
In this paper, an investigation of crying signal spectra is used to classify categories of infant cries. Three different types of crying considered in this work are hungry, sleepy and burping need. These cries are preprocessed and converted for calculation of Mel-Frequency Cepstral Coefficients (MFCC) before being classified by Convolutional Neural Network (CNN). Experimental results show that CNN based deep learning achieves high performance of 84%.
本文利用哭闹信号谱的研究方法对婴儿哭声进行分类。这项研究考虑了三种不同类型的哭泣:饥饿、困倦和打嗝。在卷积神经网络(CNN)分类之前,这些叫声经过预处理和转换,用于计算Mel-Frequency倒谱系数(MFCC)。实验结果表明,基于CNN的深度学习达到了84%的高性能。
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引用次数: 2
Adaptive Image Enhancement for Automatic Complicated G-band Chromosome Number Determination 复杂g带染色体数目自动确定的自适应图像增强
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990254
P. Wayalun, Kanuengnij Kubola
The light microscopic image of the chromosome is one of the sources to diagnose genetic disorders. Chromosome counting is the first step for diagnosing genetic abnormalities. However, in the case of complicated chromosome pattern in images, it still needs improvement due to its complication and poor image quality. Moreover, every chromosome images are different in contrast and brightness. Therefore, in order to achieve a better performance in chromosome counting, the complicated chromosome images need to be specially enhanced. This paper proposes a technique called Adaptive Complicated Chromosome Image Enhancement (ACCIE) using the determining threshold value method, and the dynamically determining intensity adjustment method. The proposed method helps to generate a proper chromosome skeletonization and yields 86.81% for complicated chromosome number determination.
染色体的光镜图像是诊断遗传疾病的来源之一。染色体计数是诊断基因异常的第一步。然而,在图像中染色体模式复杂的情况下,由于其复杂性和图像质量较差,仍然需要改进。此外,每个染色体图像的对比度和亮度都不同。因此,为了获得更好的染色体计数性能,需要对复杂的染色体图像进行特殊的增强。本文提出了一种采用确定阈值法和动态确定强度调整法的自适应复杂染色体图像增强技术(ACCIE)。所提出的方法有助于生成合适的染色体骨架,对复杂染色体数目的测定率为86.81%。
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引用次数: 3
Polyvinyl alcohol-carboxymethyl cellulose scaffolds for cartilage tissue formation 用于软骨组织形成的聚乙烯醇-羧甲基纤维素支架
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990252
Jirapat Namkaew, Nuttapong Sawaddee, Supansa Yodmuang
Cartilage has limited intrinsic capacity for self-repair after injury due to a lack of blood supply and low cell density. Tissue engineering holds promise for building cartilage grafts that withstand the stresses in joint. Major challenges of functional cartilage tissue development are scaffolding materials and structure of scaffold to support cartilage tissue formation. Scaffolds for engineered cartilage have been involved with the use of synthetic and natural polymers. Synthetic polymers provide well-control mechanical properties, while they are relatively inert to cell adhesion and tissue formation. Instead, natural polymers allow inherent cellular interaction and are present in abundance. In this study, polyvinyl alcohol (PVA) and carboxymethyl cellulose (CMC) were combined to form copolymer solution used in porous scaffold fabrication. Our goal was to investigate effects of PVA/CMC complex network on pore formation in scaffold and on cartilage tissue development. We found that addition of CMC into polymer solution could modulate scaffold architecture and swelling abilities. Fourier transform Infrared Spectroscopy (FTIR) of PVA/CMC scaffold showed the peak at 1599 cm−1 of C=O group, indicating the incorporation of CMC into the scaffold. Chondrocyte viability was observed up to 14 days post-cell seeding. These data suggested that PVA/CMC porous scaffold could be used in cartilage tissue repair.
由于缺乏血液供应和低细胞密度,软骨损伤后的自我修复能力有限。组织工程为构建能够承受关节应力的软骨移植物提供了希望。支撑软骨组织形成的支架材料和支架结构是功能性软骨组织发育的主要挑战。工程软骨支架的使用涉及合成和天然聚合物。合成聚合物具有良好的机械控制性能,同时对细胞粘附和组织形成相对惰性。相反,天然聚合物允许固有的细胞相互作用,并且大量存在。本研究将聚乙烯醇(PVA)与羧甲基纤维素(CMC)结合形成共聚物溶液,用于多孔支架的制备。我们的目的是研究PVA/CMC复合物网络对支架孔形成和软骨组织发育的影响。我们发现在聚合物溶液中加入CMC可以调节支架的结构和膨胀能力。PVA/CMC支架的傅里叶变换红外光谱(FTIR)显示,C=O基团在1599 cm−1处出现峰值,表明CMC已掺入支架中。在细胞播种后14天观察软骨细胞活力。提示PVA/CMC多孔支架可用于软骨组织修复。
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引用次数: 3
Smart Control of Hearing Aid Using EEG 基于脑电图的助听器智能控制
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990268
A. Noymai, Krit Janard, Sangvorn Seesutas, Tharapong Soonrach, P. Israsena
In this work, we experimented with the use of EEG signal to control a beamforming function of a hearing aid. An external EEG sensing system was designed and paired with a hearing aid. EEG signal was continuously read, with artifacts resulted from intentional eye blinks interpreted based on our average and variance model to identify the wearer’s intention to change the mode of the hearing aid. Based on the received command, the hearing aid would function either in an Omni-directional fashion, or directionally based on the designed beam forming structure. Experiments on experienced EEG users and volunteers were carried out to collect data to develop our decision model. The volunteers group was then retested to confirm the accuracy of the developed model. It was found that, in the controlled situation 100% accuracy was achieved, indicating the potential use of EEG as an enabler for smart control of hearing aid.
在这项工作中,我们尝试使用脑电图信号来控制助听器的波束形成功能。设计了一种外接式脑电传感系统,并与助听器配对。连续读取EEG信号,根据我们的平均和方差模型解释故意眨眼产生的伪影,以确定佩戴者改变助听器模式的意图。根据接收到的指令,助听器将以全向方式或基于设计的波束形成结构的定向方式发挥作用。在有经验的脑电图使用者和志愿者身上进行实验,收集数据来发展我们的决策模型。然后对志愿者组进行重新测试,以确认开发的模型的准确性。研究发现,在受控情况下,EEG的准确率达到100%,这表明EEG有可能成为助听器智能控制的推动者。
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引用次数: 1
Design and Fabrication of a Multi-Material Neurosurgical Simulator for an Endoscopic Third Ventriculostomy 内镜下第三脑室造口多材料神经外科模拟器的设计与制造
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990334
Hannah Riedle, Peter Wittmann, J. Franke, K. Rössler
Haptic surgical simulators can improve skills and knowledge through experience. One possible application is the training of the high-risk procedure of an endoscopic third ventriculostomy (ETV) to treat an occlusive hydrocephalus. This study presents the development of a neurosurgical simulator optimized for automated manufacturing, while maintaining anatomical details and a variety of material properties. The core of the simulator is a 3D printed silicone model of the ventricular system, embedded in soft silicone gel, simulating the brain matter. Hard anatomical elements and a dynamic body fluid system complete the setup. The evaluation of the simulator by a medical expert shows that the anatomical geometries are realistic; the material properties however still need improvement.
触觉外科模拟器可以通过经验提高技能和知识。一个可能的应用是训练高风险的内镜第三脑室造口术(ETV)治疗闭塞性脑积水。本研究介绍了一种神经外科模拟器的开发,该模拟器针对自动化制造进行了优化,同时保持了解剖细节和各种材料特性。模拟器的核心是3D打印的心室系统硅胶模型,嵌入柔软的硅胶中,模拟大脑物质。硬解剖元素和动态体液系统完成设置。医学专家对仿真器的评价表明,该仿真器的解剖几何形状逼真;但材料性能仍有待改进。
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引用次数: 0
Force Sensor for Measuring Plantar Pressure 测量足底压力的力传感器
Pub Date : 2019-11-01 DOI: 10.1109/BMEiCON47515.2019.8990304
Ms. Thitirat Teechot, Ms. Areerat Maneerat, Ms. Inarm Sansutnanont, Ms. Ornnattida Ornketphon, Ms. Treesukon Treebupachatsakul, C. Pintavirooj
A foot is the importance organs that bear the weight of the entire body. Nowadays, the improper weight distribution of the sole causes damage to the body such as plantar fasciitis and the incidence of pressure injury in the sole, which lead to long-term effect. Shoes that are suitable to the person’s feet condition including using shoe accessories in each person can help to relieve initial symptoms. However, the weight that presses to each part of the sole is different. Therefore, measured the pressed weight of each part of sole can be used to create the proper shoes accessories, which help balancing the force for individual foot condition. This research aims to improve the shoe accessory product by using the Fore sensor with the display report of graphical user interface color map for measuring the real-time pressure on moving plantar. The data from sensor was wirelessly sent to the computer, which then displayed the image results. From the result of measured pressured on planar indicated that our Force sensor padder can help patient correctly control the weight distribution of the body to make the muscles of legs and feet to function effectively.
脚是承受整个身体重量的重要器官。如今,由于脚底重量分布不当,造成足底筋膜炎等对身体的伤害,以及脚底压伤的发生,导致长期影响。适合个人脚部状况的鞋子,包括在每个人身上使用鞋配件,可以帮助缓解最初的症状。然而,压在鞋底每个部位的重量是不同的。因此,测量鞋底各部分的受压重量可以用来制作合适的鞋配件,这有助于平衡个人脚部的受力情况。本研究的目的是利用Fore传感器,通过图形用户界面颜色图的显示报告来实时测量运动脚底的压力,从而改进鞋具产品。来自传感器的数据被无线发送到计算机,然后计算机显示图像结果。从平面上的压力测量结果表明,我们的力传感器垫可以帮助患者正确控制身体的重量分布,使腿脚肌肉有效地发挥作用。
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引用次数: 0
期刊
2019 12th Biomedical Engineering International Conference (BMEiCON)
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