Pub Date : 2024-05-01Epub Date: 2024-03-06DOI: 10.1177/00369330241234688
Tuğba Öz, Nurdan Demirci
Background and aim: This study was carried out to determine the effect of the use of "virtual reality glasses," on anxiety, pain, and satisfaction level in order to reduce anxiety and pain during intrauterine device (IUD) insertion, which is a painful and stressful procedure for women and to divert attention to increase satisfaction.
Methods: This randomized controlled study in the gynecology clinic of a state hospital with 80 women who were accepted to participate in the study. Data were collected using structured patient information form, numerical pain rating scale, state-trait anxiety inventory, patient satisfaction evaluation form, and virtual reality glasses.
Results: Post-procedural pain scores in the control group after IUD application were higher than post-procedural pain in the virtual reality group. Measurements of post-procedure anxiety in the control group were higher than measurements of post-procedural in the virtual reality group. Satisfaction levels of women with virtual reality glasses during IUD insertion were also found to be high.
Conclusions: It was determined that the use of virtual reality glasses, one of the methods of distraction during IUD insertion, was effective in reducing pain and anxiety and increasing patient satisfaction.
{"title":"The effect of virtual reality glasses applied during intrauterine device insertion on pain, anxiety and satisfaction: Randomized controlled study.","authors":"Tuğba Öz, Nurdan Demirci","doi":"10.1177/00369330241234688","DOIUrl":"10.1177/00369330241234688","url":null,"abstract":"<p><strong>Background and aim: </strong>This study was carried out to determine the effect of the use of \"virtual reality glasses,\" on anxiety, pain, and satisfaction level in order to reduce anxiety and pain during intrauterine device (IUD) insertion, which is a painful and stressful procedure for women and to divert attention to increase satisfaction.</p><p><strong>Methods: </strong>This randomized controlled study in the gynecology clinic of a state hospital with 80 women who were accepted to participate in the study. Data were collected using structured patient information form, numerical pain rating scale, state-trait anxiety inventory, patient satisfaction evaluation form, and virtual reality glasses.</p><p><strong>Results: </strong>Post-procedural pain scores in the control group after IUD application were higher than post-procedural pain in the virtual reality group. Measurements of post-procedure anxiety in the control group were higher than measurements of post-procedural in the virtual reality group. Satisfaction levels of women with virtual reality glasses during IUD insertion were also found to be high.</p><p><strong>Conclusions: </strong>It was determined that the use of virtual reality glasses, one of the methods of distraction during IUD insertion, was effective in reducing pain and anxiety and increasing patient satisfaction.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"37-44"},"PeriodicalIF":2.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1177/00369330231225894
{"title":"Scottish Society of Physicians 65th Annual Meeting.","authors":"","doi":"10.1177/00369330231225894","DOIUrl":"https://doi.org/10.1177/00369330231225894","url":null,"abstract":"","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"69 2","pages":"NP1-NP17"},"PeriodicalIF":2.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2024-03-01DOI: 10.1177/00369330241236945
Sirjhun Patel, Wei Han Ong, Caroline Cobb, Stewart Gillan
Background: We explore an innovative approach by transforming patient information leaflet (PILs) into Quick Response (QR) code linked patient information videos (PIVs) in ophthalmology. Our objectives are to assess the subjective utility of a PIV on glaucoma and analyse the use of QR codes as a delivery method.
Methods: A prospective study was conducted in Ninewells Hospital, NHS Tayside. A glaucoma PIV was created and linked to a QR code provided to 130 glaucoma patients. Pre- and post-video questionnaires evaluated the patients' perception of using a QR code and subjective improvement in their understanding of glaucoma.
Results: Out of 102 responses collected, 55% of patients had no prior experience with QR codes. However, 81% of patients were able to watch the PIV. The average view duration of the video was 3:26, with 82.5% view retention. Statistically significant improvement in glaucoma knowledge was observed across all six areas questioned (p < 0.001) using a 5-point Likert scale. Overall, 70% of patients preferred PIVs over PILs, and 77% acknowledged that PIVs could be a sustainable alternative.
Conclusion: QR codes for delivering PIVs were well-received, with patients finding them easy to use. Our PIV on glaucoma effectively enhanced patients' understanding of the condition.
背景:我们探索了一种创新方法,将眼科患者信息宣传单(PIL)转化为与快速反应(QR)代码链接的患者信息视频(PIV)。我们的目标是评估 PIV 在青光眼方面的主观效用,并分析使用 QR 码作为传递方法的情况:方法:在泰赛德国家医疗服务系统的尼尼韦尔斯医院开展了一项前瞻性研究。制作了青光眼 PIV,并与提供给 130 名青光眼患者的 QR 码相链接。视频播放前和播放后的问卷调查评估了患者对使用 QR 码的感知以及对青光眼理解的主观改进:在收集到的 102 份答复中,55% 的患者以前没有使用过二维码。然而,81% 的患者能够观看 PIV。视频的平均观看时长为 3:26,观看保留率为 82.5%。据统计,患者在所有六个方面的青光眼知识都有了明显的提高(p 结论:青光眼知识的提高是一个长期的过程:用于提供 PIV 的 QR 码广受欢迎,患者认为它们易于使用。我们关于青光眼的 PIV 有效地提高了患者对青光眼的认识。
{"title":"Patient information videos via QR codes: An innovative and sustainable approach in ophthalmology.","authors":"Sirjhun Patel, Wei Han Ong, Caroline Cobb, Stewart Gillan","doi":"10.1177/00369330241236945","DOIUrl":"10.1177/00369330241236945","url":null,"abstract":"<p><strong>Background: </strong>We explore an innovative approach by transforming patient information leaflet (PILs) into Quick Response (QR) code linked patient information videos (PIVs) in ophthalmology. Our objectives are to assess the subjective utility of a PIV on glaucoma and analyse the use of QR codes as a delivery method.</p><p><strong>Methods: </strong>A prospective study was conducted in Ninewells Hospital, NHS Tayside. A glaucoma PIV was created and linked to a QR code provided to 130 glaucoma patients. Pre- and post-video questionnaires evaluated the patients' perception of using a QR code and subjective improvement in their understanding of glaucoma.</p><p><strong>Results: </strong>Out of 102 responses collected, 55% of patients had no prior experience with QR codes. However, 81% of patients were able to watch the PIV. The average view duration of the video was 3:26, with 82.5% view retention. Statistically significant improvement in glaucoma knowledge was observed across all six areas questioned (p < 0.001) using a 5-point Likert scale. Overall, 70% of patients preferred PIVs over PILs, and 77% acknowledged that PIVs could be a sustainable alternative.</p><p><strong>Conclusion: </strong>QR codes for delivering PIVs were well-received, with patients finding them easy to use. Our PIV on glaucoma effectively enhanced patients' understanding of the condition.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"45-52"},"PeriodicalIF":1.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139997390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1177/00369330231221234
Amanda A Myers, Ashish M Kamat
{"title":"Statins and BCG response: Is there more to the story?","authors":"Amanda A Myers, Ashish M Kamat","doi":"10.1177/00369330231221234","DOIUrl":"10.1177/00369330231221234","url":null,"abstract":"","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"69 1","pages":"1-2"},"PeriodicalIF":2.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140336794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2023-12-05DOI: 10.1177/00369330231213981
Judith Johnson, Lucy Pointon, Rebecca Talbot, Rebecca Coleman, Luke Budworth, Ruth Simms-Ellis, Katharina Vogt, Dialechti Tsimpida, Chandra Shekha Biyani, Reema Harrison, Gloria Cheung, Colin Melville, Vijay Jayagopal, William Lea
Background: Poor mental health in medical students is a global concern. Effective interventions are required, which are tailored towards the training-related stressors medical students experience. The Reboot coaching programme is an online, tailored intervention based on cognitive-behavioural principles.
Aims: To evaluate whether the Reboot coaching programme tailored for medical students was feasible and associated with improvements in mental health outcome indicators.
Methods: Medical students participated in two group online workshops and a one-to-one coaching call with a Reboot-trained licensed psychological therapist. Participants provided data at: baseline (T1), post-workshops (T2), post-coaching call (T3) and 4-month follow-up (T4). Outcome measures included resilience, confidence, burnout and depression. Feedback was provided regarding the workshops at T2.
Results: 115 participants (93/80.9% women; mage = 23.9; SD = 2.8) were recruited, 83 (72.2%) completed all intervention elements and 82 (71.3%) provided T4 data, surpassing recruitment and retention targets. There were significant improvements following baseline in resilience (ps < .001), confidence (ps < .001), burnout (ps < .001) and depression (ps ≤ .001). Most participants agreed the workshops imparted useful skills (n = 92; 99%) and would recommend Reboot to others (n = 89; 95.6%).
Conclusions: Existing interventions have produced mixed results regarding their effectiveness in improving medical students' mental health. Reboot is a feasible intervention in this group which is associated with improvements in resilience, confidence, burnout and depression. Further controlled studies of Reboot are now needed.
{"title":"Reboot coaching programme: a mixed-methods evaluation assessing resilience, confidence, burnout and depression in medical students.","authors":"Judith Johnson, Lucy Pointon, Rebecca Talbot, Rebecca Coleman, Luke Budworth, Ruth Simms-Ellis, Katharina Vogt, Dialechti Tsimpida, Chandra Shekha Biyani, Reema Harrison, Gloria Cheung, Colin Melville, Vijay Jayagopal, William Lea","doi":"10.1177/00369330231213981","DOIUrl":"10.1177/00369330231213981","url":null,"abstract":"<p><strong>Background: </strong>Poor mental health in medical students is a global concern. Effective interventions are required, which are tailored towards the training-related stressors medical students experience. The Reboot coaching programme is an online, tailored intervention based on cognitive-behavioural principles.</p><p><strong>Aims: </strong>To evaluate whether the Reboot coaching programme tailored for medical students was feasible and associated with improvements in mental health outcome indicators.</p><p><strong>Methods: </strong>Medical students participated in two group online workshops and a one-to-one coaching call with a Reboot-trained licensed psychological therapist. Participants provided data at: baseline (T1), post-workshops (T2), post-coaching call (T3) and 4-month follow-up (T4). Outcome measures included resilience, confidence, burnout and depression. Feedback was provided regarding the workshops at T2.</p><p><strong>Results: </strong>115 participants (93/80.9% women; <i>m</i>age = 23.9; <i>SD </i>= 2.8) were recruited, 83 (72.2%) completed all intervention elements and 82 (71.3%) provided T4 data, surpassing recruitment and retention targets. There were significant improvements following baseline in resilience (<i>ps </i>< .001), confidence (<i>ps </i>< .001), burnout (<i>ps </i>< .001) and depression (<i>ps </i>≤ .001). Most participants agreed the workshops imparted useful skills (n = 92; 99%) and would recommend Reboot to others (n = 89; 95.6%).</p><p><strong>Conclusions: </strong>Existing interventions have produced mixed results regarding their effectiveness in improving medical students' mental health. Reboot is a feasible intervention in this group which is associated with improvements in resilience, confidence, burnout and depression. Further controlled studies of Reboot are now needed.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"10-17"},"PeriodicalIF":2.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10986146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138482971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2023-11-13DOI: 10.1177/00369330231213935
Jamie Krishnan, Andrew Symington, Neil Kernohan, Suan Bray, Allison Robertson, Ghulam Nabi
Background: Cardiovascular disease affects over 7 million people in the UK and statins are often prescribed to mitigate cardiovascular risks. The effect of statins on a number of cancers is debated and their effect on Bacillus Calmette-Guérin (BCG) responsiveness in non-muscle invasive urinary bladder cancer (NMIBC) is not fully understood.
Aims: This study aims to explore the difference in HMG Co-A reductase (HMGCR) expression in NMIBC on immunochemistry in BCG responders and non-responders while on statins.
Method: Three hundred and thirty-two cases of intravesical BCG treatment for high-risk NMIBC between November 2003 and December 2017 were identified. Patients taking statins for at least 12 months before the diagnosis of NIMBC and with a follow-up of at least 5 years were included. They were divided into BCG responders and non-responders. Tumour tissue from these patients was immunohistochemically stained and quantitative image analysis carried out to assess and compare HMGCR expression in the groups.
Results & conclusion: This study showed a differential expression of HMGCR in responders vs. non-responders to BCG for high-risk NMIBC on statins. This data should form the basis of a further research and multi-centre study in a larger cohort, using HMGCR as a biomarker of response in patients on statins.
{"title":"HMG co-reductase expression and response to intravesical Bacillus Calmette-Guérin in patients with high grade non-muscle invasive urinary bladder cancer receiving statins.","authors":"Jamie Krishnan, Andrew Symington, Neil Kernohan, Suan Bray, Allison Robertson, Ghulam Nabi","doi":"10.1177/00369330231213935","DOIUrl":"10.1177/00369330231213935","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular disease affects over 7 million people in the UK and statins are often prescribed to mitigate cardiovascular risks. The effect of statins on a number of cancers is debated and their effect on Bacillus Calmette-Guérin (BCG) responsiveness in non-muscle invasive urinary bladder cancer (NMIBC) is not fully understood.</p><p><strong>Aims: </strong>This study aims to explore the difference in HMG Co-A reductase (HMGCR) expression in NMIBC on immunochemistry in BCG responders and non-responders while on statins.</p><p><strong>Method: </strong>Three hundred and thirty-two cases of intravesical BCG treatment for high-risk NMIBC between November 2003 and December 2017 were identified. Patients taking statins for at least 12 months before the diagnosis of NIMBC and with a follow-up of at least 5 years were included. They were divided into BCG responders and non-responders. Tumour tissue from these patients was immunohistochemically stained and quantitative image analysis carried out to assess and compare HMGCR expression in the groups.</p><p><strong>Results & conclusion: </strong>This study showed a differential expression of HMGCR in responders vs. non-responders to BCG for high-risk NMIBC on statins. This data should form the basis of a further research and multi-centre study in a larger cohort, using HMGCR as a biomarker of response in patients on statins.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"3-9"},"PeriodicalIF":2.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01Epub Date: 2023-12-18DOI: 10.1177/00369330231221235
James Lucocq, Leo Morgan, Ketan Rathod, Magdalena Szewczyk-Bieda, Ghulam Nabi
Introduction: The updated Bosniak classification in 2019 (v2019) addresses vague imaging terms and revises the criteria with the intent to categorise a higher proportion of cysts in lower-risk groups and reduce benign cyst resections. The aim of the present study was to compare the diagnostic accuracy and inter-observer agreement rate of the original (v2005) and updated classifications (v2019).
Method: Resected/biopsied cysts were categorised according to Bosniak classifications (v2005 and v2019) and the diagnostic accuracy was assessed with reference to histopathological analysis. The inter-observer agreement of v2005 and v2019 was determined.
Results: The malignancy rate of the cohort was 83.6% (51/61). Using v2019, a higher proportion of malignant cysts were categorised as Bosniak ≥ III (88.2% vs 84.3%) and a significantly higher percentage were categorised as Bosniak IV (68.9% vs 47.1%; p = 0.049) in comparison to v2005. v2019 would have resulted in less benign cyst resections (13.5% vs 15.7%). Calcified versus non-calcified cysts had lower rates of malignancy (57.1% vs 91.5%; RR,0.62; p = 0.002). The inter-observer agreement of v2005 was higher than that of v2019 (kappa, 0.70 vs kappa, 0.43).
Discussion: The updated classification improves the categorisation of malignant cysts and reduces benign cyst resection. The low inter-observer agreement remains a challenge to the updated classification system.
导言:2019 年更新的 Bosniak 分类(v2019)解决了成像术语模糊的问题,并修订了标准,旨在将更高比例的囊肿归入低风险组,减少良性囊肿切除。本研究旨在比较原始分类标准(v2005)和更新后的分类标准(v2019)的诊断准确性和观察者之间的一致率:根据波什尼亚克分类法(v2005 和 v2019)对切除/活检的囊肿进行分类,并参照组织病理学分析评估诊断准确性。结果表明,v2005 和 v2019 的观察者间一致性良好:结果:队列中的恶性肿瘤率为83.6%(51/61)。使用 v2019,与 v2005 相比,恶性囊肿被归类为 Bosniak ≥ III 的比例更高(88.2% vs 84.3%),被归类为 Bosniak IV 的比例明显更高(68.9% vs 47.1%;p = 0.049)。钙化与非钙化囊肿的恶性率较低(57.1% vs 91.5%;RR,0.62;p = 0.002)。v2005的观察者间一致性高于v2019(kappa, 0.70 vs kappa, 0.43):讨论:更新后的分类改进了恶性囊肿的分类,减少了良性囊肿的切除。观察者之间的一致性较低仍是更新版分类系统面临的挑战。
{"title":"Validation of the updated Bosniak classification (2019) in pathologically confirmed CT-categorised cysts.","authors":"James Lucocq, Leo Morgan, Ketan Rathod, Magdalena Szewczyk-Bieda, Ghulam Nabi","doi":"10.1177/00369330231221235","DOIUrl":"10.1177/00369330231221235","url":null,"abstract":"<p><strong>Introduction: </strong>The updated Bosniak classification in 2019 (v2019) addresses vague imaging terms and revises the criteria with the intent to categorise a higher proportion of cysts in lower-risk groups and reduce benign cyst resections. The aim of the present study was to compare the diagnostic accuracy and inter-observer agreement rate of the original (v2005) and updated classifications (v2019).</p><p><strong>Method: </strong>Resected/biopsied cysts were categorised according to Bosniak classifications (v2005 and v2019) and the diagnostic accuracy was assessed with reference to histopathological analysis. The inter-observer agreement of v2005 and v2019 was determined.</p><p><strong>Results: </strong>The malignancy rate of the cohort was 83.6% (51/61). Using v2019, a higher proportion of malignant cysts were categorised as Bosniak ≥ III (88.2% vs 84.3%) and a significantly higher percentage were categorised as Bosniak IV (68.9% vs 47.1%; p = 0.049) in comparison to v2005. v2019 would have resulted in less benign cyst resections (13.5% vs 15.7%). Calcified versus non-calcified cysts had lower rates of malignancy (57.1% vs 91.5%; RR,0.62; p = 0.002). The inter-observer agreement of v2005 was higher than that of v2019 (kappa, 0.70 vs kappa, 0.43).</p><p><strong>Discussion: </strong>The updated classification improves the categorisation of malignant cysts and reduces benign cyst resection. The low inter-observer agreement remains a challenge to the updated classification system.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"18-23"},"PeriodicalIF":2.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138804380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-27DOI: 10.1177/00369330231222798
{"title":"Abstract.","authors":"","doi":"10.1177/00369330231222798","DOIUrl":"https://doi.org/10.1177/00369330231222798","url":null,"abstract":"","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"369330231222798"},"PeriodicalIF":2.7,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01Epub Date: 2023-09-11DOI: 10.1177/00369330231186434
İrfan Küçük, Yusuf Yazgan, Ersin Tural, İdris Yıldırım, Tuğba Akbaş Şimşek, Başak Çakır Güney, Mustafa Kaplan
Objectives: We aimed to determine whether inflammatory indexes (II), including the neutrophil-lymphocyte ratio (NLR), the C-reactive protein (CRP) to albumin ratio (CAR), the CRP-lymphocyte ratio (CLR), and the systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP).
Backgrounds: Because of the spontaneous clearance, it is mandatory to ascertain the presence of CBDSs before ERCP.
Methods: Retrospectively, we evaluated two groups. Group A included 96 records in which CBDSs existed in magnetic resonance cholangiopancreatography (MRCP) and ERCP. Group B included 36 records in which CBDSs existed in MRCP but not ERCP. IIs were calculated on presentation and before ERCP.
Results: Stone detection in ERCP had a 3.992-fold (95% 1.769-9.007) higher probability with a stone larger than 3.25 mm in MRCP. Before ERCP, CAR, and CLR values were higher in group A than in group B (3.88 [1.25-14.14] and 1.24 [0.50-9.66], p = 0.027 versus 8.79 [2.19-35] and 2.67 [1.02-20.05], p = 0.029, respectively). Higher CRP, CAR, and CLR values were considered significant for detecting a stone in ERCP (AUC: 0.627 [0.519-0.739], 0.625 [0.513-0.737], and 0.624 [0.514-0.734], respectively).
Conclusion: Low CRP, CAR, and CLR values might associate with the spontaneous migration of CBDS.
{"title":"Can inflammatory indexes predict the spontaneous passage of common bile duct stones?","authors":"İrfan Küçük, Yusuf Yazgan, Ersin Tural, İdris Yıldırım, Tuğba Akbaş Şimşek, Başak Çakır Güney, Mustafa Kaplan","doi":"10.1177/00369330231186434","DOIUrl":"10.1177/00369330231186434","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to determine whether inflammatory indexes (II), including the neutrophil-lymphocyte ratio (NLR), the C-reactive protein (CRP) to albumin ratio (CAR), the CRP-lymphocyte ratio (CLR), and the systemic immune-inflammation index (SIII) can be diagnostic for common bile duct stones (CBDSs) excretion before endoscopic retrograde cholangiopancreatography (ERCP).</p><p><strong>Backgrounds: </strong>Because of the spontaneous clearance, it is mandatory to ascertain the presence of CBDSs before ERCP.</p><p><strong>Methods: </strong>Retrospectively, we evaluated two groups. Group A included 96 records in which CBDSs existed in magnetic resonance cholangiopancreatography (MRCP) and ERCP. Group B included 36 records in which CBDSs existed in MRCP but not ERCP. IIs were calculated on presentation and before ERCP.</p><p><strong>Results: </strong>Stone detection in ERCP had a 3.992-fold (95% 1.769-9.007) higher probability with a stone larger than 3.25 mm in MRCP. Before ERCP, CAR, and CLR values were higher in group A than in group B (3.88 [1.25-14.14] and 1.24 [0.50-9.66], p<i> = </i>0.027 versus 8.79 [2.19-35] and 2.67 [1.02-20.05], p<i> = </i>0.029<i>,</i> respectively). Higher CRP, CAR, and CLR values were considered significant for detecting a stone in ERCP (AUC: 0.627 [0.519-0.739], 0.625 [0.513-0.737], and 0.624 [0.514-0.734], respectively).</p><p><strong>Conclusion: </strong>Low CRP, CAR, and CLR values might associate with the spontaneous migration of CBDS.</p>","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"159-165"},"PeriodicalIF":2.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10257148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}