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Assessing the attitude of surgical trainees towards virtual reality simulation: A national cross-sectional questionnaire study 评估外科培训生对虚拟现实模拟的态度:一项全国性横断面问卷研究
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-30 DOI: 10.1177/00369330221103279
Harman Khatkar, Ashley Ferro, Sanjeev Kotecha, M. Prokopenko, A. Evans, J. Kyriakides, Jonathan Botterill, Miljyot Singh Sangha, Abbas See, Ryan Kerstein
Background We performed a cross sectional study to determine the attitudes of surgical trainees and medical students towards virtual reality (VR) simulation in surgical training. A survey was devised through an iterative process before distribution to surgical trainees, foundation year doctors and medical students through online platforms. Methods The survey was disseminated within the United Kingdom through social media and email correspondence, in co-operation with national surgical organisations. 91 trainees responded from a variety of clinical specialities. Results VR technology in surgical training was viewed positively, with 91.3% of trainees agreeing that VR should be both an adjunct in surgical training as well as a competency-based assessment tool. Barriers to access were present, with access notably more challenging for senior surgeons. Conclusion Virtual reality surgical simulation in surgical training is beginning to emerge as a genuine high-fidelity, low-risk solution to the lack of surgical case volume trainees are currently experiencing.
背景我们进行了一项横断面研究,以确定外科学员和医学生在外科培训中对虚拟现实(VR)模拟的态度。在通过在线平台分发给外科实习生、基础年医生和医学生之前,通过迭代过程设计了一项调查。方法与国家外科组织合作,通过社交媒体和电子邮件在英国境内传播该调查。91名学员来自不同的临床专业。结果手术培训中的虚拟现实技术得到了积极评价,91.3%的学员认为虚拟现实既是手术培训的辅助手段,也是基于能力的评估工具。准入存在障碍,尤其是对资深外科医生来说,准入更具挑战性。结论外科培训中的虚拟现实外科模拟正开始成为一种真正的高保真、低风险的解决方案,以解决受训人员目前缺乏外科病例的问题。
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引用次数: 1
Relationship between BMI, CT-derived body composition and colorectal neoplasia in a bowel screening population 肠道筛查人群中BMI、CT衍生的身体成分与结直肠肿瘤的关系
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-22 DOI: 10.1177/00369330221102237
Domenic Di Rollo, J. McGovern, Christopher Morton, Gillian Miller, R. Dolan, P. Horgan, D. McMillan, D. Mansouri
Introduction Obesity is associated with an increased risk of colorectal cancer (CRC). Unlike the indirect measures such as BMI, CT-Body composition (CT-BC) allows for the assessment of both volume and distribution of adipose tissue. Therefore, the aim of this study was to examine the relationship between host characteristics, BMI, CT-BC measurements and the incidence of colorectal neoplasia. Methods Patients undergoing CT Colonography (CTC) as part of the Scottish Bowel Screening Programme, between July 2009 and February 2016, were eligible for inclusion. Data were collected including demographic data, clinicopathological variables and CT-BC measurements including skeletal muscle index (SMI), subcutaneous fat index (SFI) and visceral fat area (VFA). CTC, colonoscopy, and pathology reports were used to identify CRC incidence. Associations between demographic data, clinicopathological variables, CT-BC measurements, colorectal neoplasia and advanced colorectal neoplasia were analysed using univariate and multivariate binary logistics regression. Results 286 patients met the inclusion criteria. Neoplasia was detected in 105 (37%) of the patients with advanced neoplasia being detected in 72 (69%) of patients. On multivariate analysis sex (p < 0.05) and high VFA (p < 0.001) remained independently associated with colorectal neoplasia. On multivariate analysis a high SFI (p < 0.01) remained independently associated with advanced colorectal neoplasia. BMI was not associated with either colorectal neoplasia or advanced colorectal neoplasia. Conclusion When directly compared to BMI, CT derived fat measurements were more closely associated with the degree of neoplasia in patients undergoing colorectal cancer screening. In patients investigated with CT colonography, CT adipose measures may stratify the risk and grade of neoplasia.
肥胖与结直肠癌(CRC)风险增加有关。与BMI等间接测量方法不同,CT-Body composition (CT-BC)可以评估脂肪组织的体积和分布。因此,本研究的目的是研究宿主特征、BMI、CT-BC测量与结直肠癌发病率之间的关系。方法2009年7月至2016年2月期间接受CT结肠造影(CTC)作为苏格兰肠道筛查计划一部分的患者符合纳入条件。收集的数据包括人口统计学数据、临床病理变量和CT-BC测量,包括骨骼肌指数(SMI)、皮下脂肪指数(SFI)和内脏脂肪面积(VFA)。使用CTC、结肠镜检查和病理报告来确定CRC的发病率。使用单变量和多变量二元logistic回归分析人口统计学数据、临床病理变量、CT-BC测量、结直肠肿瘤和晚期结直肠肿瘤之间的关系。结果286例患者符合纳入标准。105例(37%)晚期肿瘤患者检出瘤变,72例(69%)晚期肿瘤患者检出瘤变。在多变量分析中,性别(p < 0.05)和高VFA (p < 0.001)仍然与结直肠肿瘤独立相关。在多变量分析中,高SFI (p < 0.01)仍然与晚期结直肠肿瘤独立相关。BMI与结直肠肿瘤或晚期结直肠肿瘤均无相关性。结论与BMI直接比较,CT脂肪测量与结直肠癌筛查患者的瘤变程度关系更密切。在接受CT结肠镜检查的患者中,CT脂肪测量可以对肿瘤的风险和级别进行分层。
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引用次数: 2
Radiation safety awareness and practices amongst orthopaedic surgeons in Scotland 苏格兰整形外科医生的辐射安全意识和实践
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-09 DOI: 10.1177/00369330221099620
Gordon T Snowden, M. Jabbal, A. Akhtar
As orthopaedic surgeons we use x-rays every day; not only when diagnosing pathology but often to assist in operative management of said pathology or ensure satisfactory outcomes for our patients in clinic. An awareness of the correct use of ionising radiation in the form of fluoroscopic imaging is therefore of great importance to reduce intraoperative exposure and has led to the development of the As Little As Reasonably Achievable (ALARA) principle. The primary aim of this study is to determine the knowledge and practises of radiation safety amongst orthopaedic surgeons in Scotland. Secondary aim is to assess the prevalence of back pain and relation to lead gowns. A google forms survey containing 20 questions about both an individual's radiation practises, and knowledge and departmental practises were distributed to all 4 deaneries in Scotland. In total 72 responses were received from 20 hospitals across all 4 Scottish deaneries. This included 28 Consultants, 23 Senior trainees and 21 Junior trainees. We found that the level of radiation training and knowledge varied considerably across seniority and the nation. Of those surveyed 100% reported always wear lead aprons/gowns however only 46.2% (n = 34) frequently or always wear thyroid protection when using X-rays. Only 55% (n = 40) of those surveyed had completed a radiation safety course with this being far less likely amongst junior trainees (29%, n = 6) than amongst Consultants (82%, n = 23) and senior trainees (48%, n = 11) (p < 0.0001). To our knowledge this is the most extensive survey into the radiation practises of Orthopaedic Surgeons in the literature and shows the need for increased education and awareness of radiation safety practises, particularly amongst junior trainees.
作为整形外科医生,我们每天都使用x光片;不仅在诊断病理学时,而且通常是为了协助所述病理学的手术管理或确保我们的患者在临床上获得满意的结果。因此,正确使用荧光透视成像形式的电离辐射对减少术中暴露具有重要意义,并导致了合理实现尽可能少(ALARA)原则的发展。本研究的主要目的是确定苏格兰整形外科医生对辐射安全的认识和实践。次要目的是评估背痛的患病率以及与铅服的关系。一项谷歌表格调查包含了20个关于个人辐射实践、知识和部门实践的问题,该调查被分发给了苏格兰的所有4位院长。总共收到了来自苏格兰所有4个院长区的20家医院的72份回复。其中包括28名顾问、23名高级受训人员和21名初级受训人员。我们发现,辐射培训和知识的水平因资历和国家而异。在接受调查的人中,100%的人表示总是穿铅围裙/长袍,但只有46.2%(n = 34)在使用X射线时经常或总是佩戴甲状腺保护装置。只有55%(n = 40)接受调查的人已经完成了辐射安全课程,而在初级受训人员中,这一可能性要小得多(29%,n = 6) 在顾问中(82%,n = 23)和高级学员(48%,n = 11) (p < 0.0001)。据我们所知,这是文献中对骨科医生辐射实践最广泛的调查,表明需要加强辐射安全实践的教育和意识,特别是在初级受训人员中。
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引用次数: 2
Management of stage II seminoma: a contemporary UK perspective 第二阶段精原细胞瘤的治疗:当代英国的观点
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-04 DOI: 10.1177/00369330221099619
C. Alifrangis, D. Nicol, J. Shamash, P. Rajan
Background and Aims Testicular Germ Cell Tumours (TGCTs) are the commonest young adult male cancer, with excellent survival outcomes even with metastatic disease. Chemotherapy, radiotherapy, and surgery are international guideline-dictated standard of care (SOC) treatments for International Germ Cell Cancer Collaborative Group (IGCCCG) “good risk” TGCT, but are associated with significant toxicities. Therapy de-escalation aims to reduce treatment morbidity whilst preserving cure rates, and has been adopted by some centres for stage IIA/B seminoma. Here, we report on the contemporary UK treatment landscape for stage IIA/B seminoma. Methods A questionnaire-based survey of NHS England-designated specialist cancer centres hosting supra-regional specialist multi-disciplinary team (sMDT) services (n = 13) as well those within NHS Scotland, NHS Wales and Health and Social Care Northern Ireland. Respondents were asked to order preferences of SOC and therapy de-escalation treatments for stage IIA/B seminoma. Results We identified significant geographical heterogeneity in treatment preferences. Whilst up to a third of centres have adopted a treatment de-escalation regimen, the majority deliver combination chemotherapy or radiotherapy. Conclusion A wider recognition of UK treatment heterogeneity and consideration of therapy de-escalation strategies at supra-regional sMDTs will increase stage IIA/B seminoma treatment options as part of clinical trials with oncological and quality of life endpoints.
背景和目的睾丸生殖细胞肿瘤(TGCT)是最常见的年轻成年男性癌症,即使有转移性疾病,也有良好的生存结果。化疗、放射治疗和手术是国际生殖细胞癌症合作小组(IGCCCG)“良好风险”TGCT的国际指导方针指定的护理标准(SOC)治疗,但与显著的毒性相关。降级治疗旨在降低治疗发病率,同时保持治愈率,并已被一些IIA/B期精原细胞瘤中心采用。在这里,我们报道了当代英国IIA/B期精原细胞瘤的治疗情况。方法对英国国家医疗服务体系(NHS)指定的癌症专科中心提供跨区域专家多学科团队(sMDT)服务(n = 13) 以及苏格兰国家医疗服务体系(NHS Scotland)、威尔士国家医疗服务系统(NHS Wales)和北爱尔兰卫生和社会护理机构(Health and Social Care Northern Ireland)内部的人员。受访者被要求对IIA/B期精原细胞瘤的SOC和治疗降级治疗进行排序。结果我们发现治疗偏好存在显著的地理异质性。虽然多达三分之一的中心采用了治疗降级方案,但大多数中心提供联合化疗或放疗。结论更广泛地认识到英国治疗的异质性,并考虑超区域sMDT的治疗降级策略,将增加IIA/B期精原细胞瘤治疗的选择,作为肿瘤学和生活质量终点临床试验的一部分。
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引用次数: 4
The Relationship Between Urinary Symptom Severity And Functional Status İn Patients With Stroke. 脑卒中患者泌尿系统症状严重程度与功能状态的关系İn。
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-01 Epub Date: 2022-01-05 DOI: 10.1177/00369330211072247
Fatma Özcan, Zuhal Özişler

Background: Lower Urinary Tract Dysfunction (LUTD) is a condition that is common in stroke patients and affects their quality of life and psychological state.

Aim: To determine the factors affecting LUTD severity in stroke patients and to evaluate its relationship with functional status.

Method: 77 stroke patients were included in our study. Demographic and stroke characteristics of all patients were recorded. Functional Ambulation Scale (FAS), Functional Independence Measure (FIM), the Core Lower Urinary Tract Symptom Score (CLSS) Questionnaire, Beck Depression Scale were administered to the patient. 33 of 77 patients had urodynamic study and these patients constituted the subgroup of the study. Patients were grouped according to type of disorder, type of detrusor and detrusor sphincter dyssynergia (DSD) using urodynamic study findings.

Result: The mean CLSS of men was significantly higher than women (P = 0.017). A significant positive correlation was found between age and CLSS (P = 0.035 r = 0.24) and negative correlation was found between total FIM and all sub-parameter scores and mean of CLSS (P = 0.001 r = -0.467).

Conclusion: LUTD is common in stroke patients and the presence of urinary symptoms is associated with poor functional status. No significant relationship was observed between urodynamic data except maximum flow rate and CLSS.

背景:下尿路功能障碍(LUTD)是脑卒中患者的常见病,影响患者的生活质量和心理状态。目的:探讨影响脑卒中患者LUTD严重程度的因素及其与功能状态的关系。方法:选取77例脑卒中患者进行研究。记录所有患者的人口学特征和脑卒中特征。采用功能行走量表(FAS)、功能独立性量表(FIM)、核心下尿路症状评分问卷(CLSS)、贝克抑郁量表。77例患者中有33例进行了尿动力学研究,这些患者构成了研究的亚组。根据尿动力学研究结果,将患者按障碍类型、逼尿肌类型和逼尿肌括约肌协同障碍(DSD)进行分组。结果:男性的平均CLSS显著高于女性(P = 0.017)。年龄与CLSS呈显著正相关(P = 0.035 r = 0.24),总FIM与所有子参数得分和CLSS平均值呈负相关(P = 0.001 r = -0.467)。结论:LUTD在脑卒中患者中很常见,泌尿系统症状的出现与功能状态不佳有关。除最大流量与CLSS外,尿动力学数据之间无显著关系。
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引用次数: 3
Evaluating xanthochromia in the diagnosis of subarachnoid haemorrhage in Scotland in the Era of modern computed tomography. 在现代计算机断层扫描时代评价黄色症对苏格兰蛛网膜下腔出血的诊断价值。
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-01 Epub Date: 2022-02-01 DOI: 10.1177/00369330211072264
Stephen Rankin, Jacqueline McGuire, Mohamed Chekroud, Likhith Alakandy, Babu Mukhopadhyay

Aim: Cerebrospinal fluid (CSF) analysis for xanthochromia is routinely used to exclude subarachnoid haemorrhage (SAH). In this study, we evaluated the sensitivity and specificity of xanthochromia (by NEQAS-spectrophotometry) in routine clinical practice in three acute hospitals, in patients with suspected SAH. We explored whether including CSF red cell count (RCC) with xanthochromia improved diagnostic accuracy.

Methods: In this retrospective analysis, all xanthochromia results were assessed over three consecutive years. Clinical information and Registry data were analysed to find all patients diagnosed with SAH. We correlated xanthochromia data with clinical and radiological findings.

Results: There were 1761 xanthochromia performed. Of these, 26 (1.5%) were positive, 1624 (92%) negative and 72 (4.1%) were inconclusive. Of the 26 tests that were positive, 9 (35%) had confirmed SAH, 17 (65%) were falsely positive, with no false negative tests in our series. Xanthochromia identified 6% of all SAH diagnosed in the study. Incorporating RCC <1000 with xanthochromia, reducing false positive tests by 38% and inconclusive test by 85%.

Conclusion: The positive yield of xanthochromia is low but identified 6% of SAH. NEQAS-spectrophotometry is an excellent diagnostic method with 100% sensitivity, 99% specificity. Incorporating RCC markedly reduces false positive and inconclusive tests reducing need for further imaging.

目的:脑脊液(CSF)分析是排除蛛网膜下腔出血(SAH)的常规方法。在本研究中,我们在三家急性医院的常规临床实践中,对疑似SAH患者的黄色症(通过neqas分光光度法)的敏感性和特异性进行了评估。我们探讨了CSF红细胞计数(RCC)与黄色症是否能提高诊断准确性。方法:在回顾性分析中,对所有黄色症结果进行连续三年的评估。分析临床信息和注册数据以发现所有诊断为SAH的患者。我们将黄色症数据与临床和放射学结果相关联。结果:检出黄色症1761例。其中阳性26例(1.5%),阴性1624例(92%),不确定72例(4.1%)。在26例阳性试验中,9例(35%)确诊为SAH, 17例(65%)为假阳性,在我们的研究中没有假阴性试验。黄色症在研究中诊断的所有SAH中占6%。结论:黄色症的阳性检出率较低,但可检出6%的SAH。neqas分光光度法具有100%的灵敏度,99%的特异度。合并RCC可显著减少假阳性和不确定的检查,减少进一步影像学检查的需要。
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引用次数: 1
Evaluation of the optimal duration for retrograde intrarenal stone surgery to prevent postoperative complications 肾内结石逆行手术预防术后并发症的最佳时间评价
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-01 DOI: 10.1177/00369330221099621
Y. Yitgin, Nurullah Altınkaya, Nurmanbet Turaliev, S. Guven, R. Ergul, A. Boyuk, S. Verep, T. Tefik, M. A. Karagoz, M. Ibis, M. I. Gokce, K. Sarıca
Objective To evaluate retrograde intrarenal surgery (RIRS) outcomes and to determine the effect of operative time on complications of RIRS. Methods Patients undergoing RIRS for renal stones were evaluated. These patients were divided into two groups according to the operation time (Group 1<60 minutes and Group 2>60 minutes). Peroperative outcomes such as fluoroscopy time, stone-free rates, complications and duration of hospitalization were compared. Results Group 1 consisted of 264 patients and Group 2 consisted of 297 patients. SFR rates, duration of hospitalization, and postoperative urinary tract infection rates were similar in both groups. Fluoroscopy time was 7.8±7.3 (0-49) sec in group 1 and 13.1±9.8 (0-81) sec in group 2. Complications according to modified Clavien–Dindo classification system (MCDCS) were 13 and 32 patients (Grade 1), 31 and 63 patients (Grade 2), 1 and 1 patient (Grade 3) in group 1 and 2, respectively. There was statistical difference between the two groups in terms of duration of fluoroscopy time and the MCDCS. Although duration of hospitalization and UTI rates were higher in group 2, no statistical significance was observed among groups. Conclusion Limiting the operation time to 60 minutes in RIRS seems to be important in reducing postoperative complications.
目的评价肾内逆行手术(RIRS)的疗效,并确定手术时间对RIRS并发症的影响。方法对肾结石RIRS患者进行评价。根据手术时间将这些患者分为两组(160分钟组)。比较术后结果,如荧光透视时间、结石清除率、并发症和住院时间。结果第1组264例,第2组297例。两组的SFR发生率、住院时间和术后尿路感染率相似。第1组荧光镜检查时间为7.8±7.3(0-49)秒,第2组为13.1±9.8(0-81)秒。根据改良的Clavien-Dindo分类系统(MCDCS),第1组和第2组的并发症分别为13例和32例(1级)、31例和63例(2级)、1例和1例(3级)。两组在荧光透视持续时间和MCDCS方面存在统计学差异。尽管第2组的住院时间和尿路感染率较高,但各组之间没有观察到统计学意义。结论RIRS手术时间控制在60min对减少术后并发症有重要意义。
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引用次数: 1
Surgical skills and COVID-19 pandemic: Impact and way forward 外科技能与新冠肺炎大流行:影响和前进方向
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-05-01 DOI: 10.1177/00369330221095709
G. Nabi
The Covid-SARS-19 pandemic has changed the global ways of life, impacting various domains of living such as social life, national economies, work, and temporary curtailing of opportunities in surgical training. 1,2 The temporary cessation of skill courses and conferences by the organisations and professional bodies have impacted training of future surgical workforce. In this issue Ms Gowda et al. 3 report, impact of Covid-19 pandemic on the technical skills of urology trainees attending national BOOTS camp. 4 The study fi nds a detrimental effect of pandemic on the technical skills of trainees, whereas a similar study by Etheridge et al. from Singapore 5 showed an improvement in non-technical and team man-agement skills. Improvement in teamwork during disas-ters has also been observed in other area. 6,7 Together with other publications, the published literature provides background for the future policy making in surgical training. The observations reported by the authors suggest that lack of exposure to real-life surgical skills particularly in complex tasks such as laparoscopic suturing has resulted in poor technical skills gain by the trainees. 8 The role of simulation can help in retaining basic surgical skills and principles upto a point, but further re fi nement is only pos-sible through operating on patients in surgical operating room environment. A drop in upto 60% of operative volume based on a review of operating logbooks of trainees in Europe and USA us idea are likely the
Covid-SARS-19大流行改变了全球的生活方式,影响了各种生活领域,如社会生活、国民经济、工作和外科培训机会的暂时减少。1,2组织和专业机构暂时停止技能课程和会议,影响了未来外科工作人员的培训。在本期中,Gowda女士等人3报道了新冠肺炎大流行对参加国家BOOTS训练营的泌尿外科受训人员技术技能的影响。4该研究发现,疫情对受训人员的技术技能产生了不利影响,而Etheridge等人在新加坡进行的一项类似研究5显示,非技术和团队管理技能有所提高。在其他领域也观察到了灾难期间团队合作的改善。6,7与其他出版物一起,已发表的文献为外科培训的未来政策制定提供了背景。作者报告的观察结果表明,缺乏现实生活中的手术技能,特别是在腹腔镜缝合等复杂任务中,导致受训人员获得的技术技能较差。8模拟的作用有助于在一定程度上保留基本的手术技能和原则,但只有在手术室环境中对患者进行手术才能进一步改善。根据对欧洲和美国受训人员的操作日志的审查,手术量可能下降60%
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引用次数: 0
Matthew Baillie (1761–1823): From Shotts to Duntisbourne Abbots 马修·贝利(1761-1823):从肖茨到邓蒂斯伯恩修道院
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-11 DOI: 10.1177/00369330221093752
M. Muqit, A. Larner
Matthew Baillie was born in Shotts, Lanarkshire, Scotland in 1761 and died at Duntisbourne Abbots, Gloucestershire, England in 1823. In the intervening years he established himself as one of the foremost anatomists of his day, publishing one of the earliest treatises on pathological anatomy, and then as physician, eventually ministering to the Royal household and other notable patients and earning a considerable fortune in the process. Amongst his many honours he received an Honorary Fellowship of the Royal College of Physicians of Edinburgh, where he is commemorated in the frieze in the Great Hall. This article follows the trajectory of his career, introducing material not found in previous biographies.
Matthew Baillie于1761年出生于苏格兰拉纳克郡的Shotts,1823年死于英国格洛斯特郡的Duntisbourne Abbots。在这中间的几年里,他成为了当时最重要的解剖学家之一,出版了最早的病理解剖学论文之一,然后成为了一名医生,最终为王室和其他著名患者服务,并在这个过程中赚了一大笔钱。在他的众多荣誉中,他获得了爱丁堡皇家医学院的荣誉奖学金,在那里,他被纪念在大会堂的雕带上。这篇文章遵循了他的职业生涯轨迹,介绍了以前传记中没有的材料。
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引用次数: 1
Scottish Renal Association 苏格兰肾脏协会
IF 2.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-04 DOI: 10.1177/00369330221087797
Sylvia McConnell, R. Battle, Emma, Cannon, Samina Hussain, P. Phelan, David Turner, O. EoinD., Sullivan, K. Mylonas, Cyril, Carvalho, David P. Baird, Marie, Docherty, Carolynn Cairns, M. Kevin, Gallagher, A. Laird, C. Neil, Henderson, Tamir Chandra, Kristina, Kirschner, B. Conway, Laura, Denby, G. H. Dihazi, M. Zeisberg, J. Hughes, H. Dihazi, David, A. Ferenbach
Intro: Sodium/glucose cotransporter-2 inhibitors (SGLT2i) reduce risk of progressive kidney disease both in and out with the setting of diabetes. The aims of this study were to quantify the current uptake of canagliflozin within patients with type 2 diabetes in nephrology units within the west of Scotland and to identify barriers to prescribing. Methods: A retrospective analysis of the Scottish Electronic Renal Patient Record (SERPR) was performed to patients to secondary care nephrology services within NHS Greater Glasgow and Clyde (GGC) and NHS Lanarkshire who were eligible for SGLT2i. Canagliflozin is licensed for treatment of diabetic kidney disease (DKD) in patients with type 2 diabetes, estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m, urinary albumin:creatinine ratio (uACR) >30 mg/mmol. A questionnaire was produced to identify attitudes towards prescribing SGLT2i’s. The survey was composed of 5 questions on GoogleForms and Survey Monkey platforms. These were disseminated via email to prescribers in NHS GGC (nephrology only) and NHS Lanarkshire (nephrology and medical specialties). Results: From the retrospective SERPR analysis, there were 74 patients in NHS Lanarkshire identified as eligible, of whom 8 (11%) had been prescribed canagliflozin. In NHS GGC, 148 patients were identified as eligible of whom 57 (38.5%) had been prescribed canagliflozin. There were 58 survey responses gathered in NHS Lanarkshire and 18 responses from NHS GGC. Within NHS Lanarkshire 35.5% of respondents were consultants, 19.0% were registrars, and 34.5% were foundation or core trainee doctors. Respondents in NHS Lanarkshire felt that the main responsibility for prescribing SGLT2i lay with diabetes (55.1%), then all specialties equally (39.7%), GP (20.7%) and cardiology (17.2%). Only 24.1% of respondents in NHS Lanarkshire had started a patient on an SGLT2i and 29.3% felt they had access to adequate information to commence a patient on SGLT2i. Within NHS GGC, 72.2% of respondents were consultants and 11.1% were registrars, 83.3% had prescribed SGTL2i and 94.4% of respondents felt as though they had adequate information to commence patients of SGLT2i treatment. Within NHS GGC 61.1% of respondents felt every specialty had equal responsibility to start patients on SGLT2i, followed by diabetes (33.3%), nephrology (33.3%) and GP (27.8%). Conclusion: SGLT2i prescribing in patients with DKD remains low. A variety of factors contribute towards this, including inadequate provision of information to clinicians regarding commencing SGLT2i, concerns over serious side effects of SGLT2i (such as euglycemic DKA) and disagreement over whose responsibility it should be to commence these medications. Providing furthereducation and readily accessible prescribing resources to clinicians, and particularly to training grade doctors, may help to increase uptake of SGLT2i.
简介:钠/葡萄糖协同转运蛋白2抑制剂(SGLT2i)可降低糖尿病患者发生进展性肾病的风险。本研究的目的是量化苏格兰西部肾脏科2型糖尿病患者目前对卡格列净的摄取情况,并确定处方障碍。方法:对符合SGLT2i条件的NHS Greater Glasgow and Clyde(GGC)和NHS Lanarkshire二级护理肾病服务的患者进行苏格兰电子肾脏患者记录(SERPR)的回顾性分析。卡格列净被许可用于治疗2型糖尿病患者的糖尿病肾病(DKD),估计肾小球滤过率(eGFR)>30 ml/min/1.73 m,尿白蛋白与肌酐比值(uACR)>30 mg/mmol。制作了一份问卷,以确定对开具SGLT2i的态度。该调查由GoogleForms和SurveyMonkey平台上的5个问题组成。这些信息通过电子邮件传播给NHS GGC(仅肾脏病学)和NHS拉纳克郡(肾脏病学和医学专业)的处方医生。结果:根据回顾性SERPR分析,拉纳克郡国家医疗服务体系有74名患者符合条件,其中8人(11%)服用了卡格列净。在NHS GGC中,148名患者被确定为符合条件,其中57人(38.5%)服用了卡格列净。拉纳克郡国家医疗服务体系(NHS Lanarkshire)收集了58份调查回复,GGC收集了18份回复。在拉纳克郡的NHS中,35.5%的受访者是顾问,19.0%是注册医生,34.5%是基金会或核心实习医生。拉纳克郡国家医疗服务体系的受访者认为,开具SGLT2i处方的主要责任在于糖尿病(55.1%),然后是所有专业(39.7%)、全科医生(20.7%)和心脏病学(17.2%。在NHS GGC中,72.2%的受访者是顾问,11.1%的受访者是登记员,83.3%的受访者开过SGTL2i处方,94.4%的受访者认为他们有足够的信息来开始SGLT2i治疗。在NHS GGC中,61.1%的受访者认为每个专业都有同等的责任让患者开始服用SGLT2i,其次是糖尿病(33.3%)、肾病学(33.3%和全科医生(27.8%)。结论:DKD患者的SGLT2i处方仍然很低。多种因素导致了这种情况,包括向临床医生提供的关于开始服用SGLT2i的信息不足,对SGLT2i的严重副作用(如血糖正常的DKA)的担忧,以及对谁应该负责开始服用这些药物的分歧。为临床医生,特别是培训级医生提供进一步的教育和易于获得的处方资源,可能有助于提高SGLT2i的使用率。
{"title":"Scottish Renal Association","authors":"Sylvia McConnell, R. Battle, Emma, Cannon, Samina Hussain, P. Phelan, David Turner, O. EoinD., Sullivan, K. Mylonas, Cyril, Carvalho, David P. Baird, Marie, Docherty, Carolynn Cairns, M. Kevin, Gallagher, A. Laird, C. Neil, Henderson, Tamir Chandra, Kristina, Kirschner, B. Conway, Laura, Denby, G. H. Dihazi, M. Zeisberg, J. Hughes, H. Dihazi, David, A. Ferenbach","doi":"10.1177/00369330221087797","DOIUrl":"https://doi.org/10.1177/00369330221087797","url":null,"abstract":"Intro: Sodium/glucose cotransporter-2 inhibitors (SGLT2i) reduce risk of progressive kidney disease both in and out with the setting of diabetes. The aims of this study were to quantify the current uptake of canagliflozin within patients with type 2 diabetes in nephrology units within the west of Scotland and to identify barriers to prescribing. Methods: A retrospective analysis of the Scottish Electronic Renal Patient Record (SERPR) was performed to patients to secondary care nephrology services within NHS Greater Glasgow and Clyde (GGC) and NHS Lanarkshire who were eligible for SGLT2i. Canagliflozin is licensed for treatment of diabetic kidney disease (DKD) in patients with type 2 diabetes, estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m, urinary albumin:creatinine ratio (uACR) >30 mg/mmol. A questionnaire was produced to identify attitudes towards prescribing SGLT2i’s. The survey was composed of 5 questions on GoogleForms and Survey Monkey platforms. These were disseminated via email to prescribers in NHS GGC (nephrology only) and NHS Lanarkshire (nephrology and medical specialties). Results: From the retrospective SERPR analysis, there were 74 patients in NHS Lanarkshire identified as eligible, of whom 8 (11%) had been prescribed canagliflozin. In NHS GGC, 148 patients were identified as eligible of whom 57 (38.5%) had been prescribed canagliflozin. There were 58 survey responses gathered in NHS Lanarkshire and 18 responses from NHS GGC. Within NHS Lanarkshire 35.5% of respondents were consultants, 19.0% were registrars, and 34.5% were foundation or core trainee doctors. Respondents in NHS Lanarkshire felt that the main responsibility for prescribing SGLT2i lay with diabetes (55.1%), then all specialties equally (39.7%), GP (20.7%) and cardiology (17.2%). Only 24.1% of respondents in NHS Lanarkshire had started a patient on an SGLT2i and 29.3% felt they had access to adequate information to commence a patient on SGLT2i. Within NHS GGC, 72.2% of respondents were consultants and 11.1% were registrars, 83.3% had prescribed SGTL2i and 94.4% of respondents felt as though they had adequate information to commence patients of SGLT2i treatment. Within NHS GGC 61.1% of respondents felt every specialty had equal responsibility to start patients on SGLT2i, followed by diabetes (33.3%), nephrology (33.3%) and GP (27.8%). Conclusion: SGLT2i prescribing in patients with DKD remains low. A variety of factors contribute towards this, including inadequate provision of information to clinicians regarding commencing SGLT2i, concerns over serious side effects of SGLT2i (such as euglycemic DKA) and disagreement over whose responsibility it should be to commence these medications. Providing furthereducation and readily accessible prescribing resources to clinicians, and particularly to training grade doctors, may help to increase uptake of SGLT2i.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":"67 1","pages":"NP1 - NP24"},"PeriodicalIF":2.7,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49555625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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Scottish Medical Journal
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