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Hepatitis B and C Viruses: Prevalence and co-factors among patients with liver cirrhosis 乙型和丙型肝炎病毒:肝硬化患者中的流行率和共同因素
Pub Date : 2024-02-09 DOI: 10.31893/multiscience.2024142
Said Rahatullah Haidari
Liver cirrhosis is the final pathway of multiple chronic liver diseases and is a pathological entity defined as diffuse hepatic fibrosis and regenerative nodule formation. The objective of this study was to investigate the prevalence and co-factors of hepatitis B and C viruses among patients with liver cirrhosis. A total of 79 patients were registered from 2018 to 2022. The prevalence of liver cirrhosis in 2018, 2019, and 2020. 2021 and 2022 were 21.7%, 13.0%, 19.1%, 6.1% and 8.7%, respectively. The incidence of cirrhosis was significantly (P = 0.01) greater in rural areas than in urban areas. In addition, according to age, the incidence of cirrhosis was significantly (P = 0.001) greater in those >52 years old than in those 18-40 and 41-52 years old. Moreover, the incidence of cirrhosis was greater in females than in males, but the difference was not significant. Without that, the causes of cirrhosis for HBV, HCV and Non-B and Non-C patients were 13% and 40%, 15.7%, respectively. The results showed that causes of cirrhosis were significantly associated with HCV incidence, and the prevalence of underweight, normal, overweight, and obese individuals was 13%, 15.7%, 26.1% and 18.9%, respectively. Prevalence according to BMI categories did significantly differ among the categories. Furthermore, the incidences of diabetes mellitus for patients with HBV and HCV and for non-B and non-C individuals were 21.7%, 47% and 31.3%, respectively, but the incidence of diabetes mellitus was significantly associated with the incidence of HCV. In addition, the incidences of encephalopathy for HBV, HCV and non-B and non-C patients were 20.9%, 47.8%, and 31.3%, respectively, and for Ascites, they were 24.3%, 44.3%, and 31.4%, respectively. Finally, the incidence of cirrhosis was significantly (P = 0.001) greater in smoking patients than in nonsmokers.
肝硬化是多种慢性肝病的最终途径,是一种定义为弥漫性肝纤维化和再生结节形成的病理实体。本研究旨在调查肝硬化患者中乙型肝炎病毒和丙型肝炎病毒的流行情况和共同因素。从2018年至2022年,共登记了79名患者。2018年、2019年和2020年肝硬化的患病率分别为21.5%、21.5%和21.5%。2021年和2022年的发病率分别为21.7%、13.0%、19.1%、6.1%和8.7%。农村地区的肝硬化发病率明显高于城市地区(P = 0.01)。此外,根据年龄划分,年龄大于 52 岁者的肝硬化发病率明显高于 18-40 岁和 41-52 岁者(P = 0.001)。此外,女性肝硬化发病率高于男性,但差异不显著。除此以外,HBV、HCV 和非 B 型及非 C 型患者的肝硬化病因分别为 13%、40% 和 15.7%。结果显示,肝硬化病因与 HCV 发病率显著相关,体重不足、正常、超重和肥胖者的患病率分别为 13%、15.7%、26.1% 和 18.9%。根据体重指数分类,不同类别的患病率有显著差异。此外,HBV 和 HCV 患者以及非 B 型和非 C 型患者的糖尿病发病率分别为 21.7%、47% 和 31.3%,但糖尿病发病率与 HCV 发病率明显相关。此外,HBV、HCV、非乙型和非丙型患者的脑病发病率分别为 20.9%、47.8% 和 31.3%,腹水发病率分别为 24.3%、44.3% 和 31.4%。最后,吸烟患者的肝硬化发生率明显高于非吸烟者(P = 0.001)。
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引用次数: 0
Extraction of proteins and location of the L-ype Voltage-Dependent Ca2+ channel (CaV1.2 α1c) in pig sperm extracted from fresh, frozen and permeated semen 从新鲜、冷冻和渗透精液中提取猪精子中的 L 型电压依赖性 Ca2+ 通道(CaV1.2 α1c)蛋白质及其位置
Pub Date : 2024-02-07 DOI: 10.31893/multiscience.2024135
Edelmira Jácome Sosa, Maria de Lourdez Juarez Mosqueda, Manuel Barrientos Villeda, B. Domínguez Mancera, Pablo Delgado Sánchez, Juan Manuel Pinos, M. Barrientos Morales
Ion channels are protein structures located in the cell plasma membrane. Sperm cells require calcium ions (Ca2+) to carry out fundamental physiological processes, such as hypermotility, capacitation and acrosomal reaction. Protein extraction is the first, and most critical, stage of molecular tests (Western Blot, proteomic tests, etc). The implementation of these techniques in the study of sperm cells will allow us to understand their physiology (biomarkers) and ways of manipulation (refrigeration, cryopreservation, permeation using streptolysin O (SLO), etc.). The goal of this project was to determine whether if changes in the plasma membrane, brought on by cryopreservation or permeation with SLO, modify the Ca2+ CaV1.2 α1C channel in pig sperm cells. 2 ½ pig ejaculates were taken as working simples, and they were treated as follows: -Control (C): refrigerated semen (SR) 16°/24h; Treatment 1 (T1): SR with SLO T2: cryopreserved semen (SC); T3: SC, previously treated with SLO. It was determined that a better quantitation of proteins from the samples (p<0.001) is obtained with a (total) protein extraction buffer composed of  SDS 2% + β-Mercaptoethanol 3%. The detection of the CaV 1.2 α1C protein was done through Western Bloting, using the Rabbit anti-CaV 1.2 α1C (USA, Sigma-AldrichTM) antigen. Better visibility of the protein band of the Ca2+ channel was achieved in the C and T1 experimental groups; whereas its’ presence was not observed in T2 and T3. It was determined that the Ca2+ CaV 1.2 α1C was present in the sperm cells, and that it deteriorates once the sperm cell is frozen and permeated with SLO, which is linked to the decrease of cell viability percentages. alibri font, size 10, and single line spacing.
离子通道是位于细胞质膜上的蛋白质结构。精子细胞需要钙离子(Ca2+)来完成基本的生理过程,如过度运动、获能和顶体反应。蛋白质提取是分子检测(Western Blot、蛋白质组检测等)的第一阶段,也是最关键的阶段。在精子细胞研究中采用这些技术将使我们能够了解精子细胞的生理学(生物标志物)和操作方法(冷藏、冷冻保存、使用链霉素 O(SLO)渗透等)。本项目的目标是确定冷冻保存或 SLO 渗透是否会改变猪精子细胞的 Ca2+ CaV1.2 α1C 通道。将 2 ½ 猪的射精作为工作模拟物,并对其进行如下处理:-对照组(C):冷藏精液(SR)16°/24 小时;处理 1(T1):T2:冷冻精液(SC);T3:SC,之前用 SLO 处理过:T3:先前用 SLO 处理过的 SC。结果表明,用 SDS 2% + β-巯基乙醇 3% 组成的(总)蛋白质提取缓冲液提取样品中的蛋白质,定量效果更好(p<0.001)。使用兔抗 CaV 1.2 α1C(美国,Sigma-AldrichTM)抗原通过 Western Bloting 检测 CaV 1.2 α1C蛋白。在 C 组和 T1 实验组中,Ca2+ 通道蛋白条带的可见度较高;而在 T2 和 T3 实验组中,没有观察到 Ca2+ 通道蛋白条带的存在。实验结果表明,精子细胞中存在 Ca2+ CaV 1.2 α1C,一旦精子细胞被冷冻并被 SLO 渗透,Ca2+ CaV 1.2 α1C就会退化,这与细胞存活率的下降有关。
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引用次数: 0
The implementation of lean management in reducing waste in the emergency department 在急诊科实施精益管理减少浪费
Pub Date : 2024-02-05 DOI: 10.31893/multiscience.2024132
Rani Meidawati, Merita Arini
Emergency Department (ED) is the frontliner unit of the hospital which becomes the entry door for emergency patients who need quick and efficient treatment. Prolonged doctor’s response time results in complaints, patients feel neglected, and affect the quality of service in the emergency room. This study aims to identify waste in emergency department services and to formulate recommendations for improvement. Methods used in this study is action research. , n=10; emergency room patients/caretakers, n=10. Data were taken through in-depth interviews, data was recorded, transcribed verbatim, and content analysis was carried out. The results of this study found 4 themes; literacy and expectations of health service of waste; complexity of inhibitory factors of services; as well as potential service improvements from supporting factors. There are four types of waste including waiting time, overprocessing, motion, unnecessary inventory, and the trial carried out was shown that it can shortened the doctor’s response time by average of 1 minute 29 seconds 82 . Lean implementation is able to found waste that can be eliminated. It takes commitment from hospital staff and management to always improving and continuously evaluating the service system.
急诊科(ED)是医院的前沿科室,是急诊病人需要快速有效治疗的入口。医生反应时间过长会导致投诉,病人感到被忽视,影响急诊室的服务质量。本研究旨在找出急诊室服务中的浪费现象,并提出改进建议。本研究采用的方法是行动研究法。研究对象包括:急诊室患者/护理人员,10 人;急诊室患者/护理人员,10 人。通过深入访谈获取数据,记录数据,逐字转录,并进行内容分析。研究结果发现了 4 个主题:医疗服务对浪费的认识和期望;服务抑制因素的复杂性;以及支持因素对服务改进的潜力。浪费有四种类型,包括等待时间、过度处理、运动、不必要的库存,进行的试验表明,它可以将医生的反应时间平均缩短 1 分 29 秒82。精益实施能够发现可以消除的浪费。这需要医院员工和管理层致力于不断改进和持续评估服务系统。
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引用次数: 0
The impact of education type on employability and wages in China 中国教育类型对就业能力和工资的影响
Pub Date : 2024-02-05 DOI: 10.31893/multiscience.2024133
Xiaoyan Peng, Hasan-Basri Bakti, Abu Sufian Abu Bakar
The objective of this paper is to investigate the impact of China’s recent education policy on the labor market performance (i.e., employability and wages) of both general and vocational education graduates. The policy requires 50% of junior high school graduates to pursue secondary vocational education. The policy received public complaints because, in many parts of the world, students are free to decide on their future education. This paper measures the impacts of education type on labor market performance for both general and vocational education graduates, seeking to uncover the differing perspectives between Chinese authorities and the public. The study utilizes secondary survey data from the Chinese Social Survey 2021 (CSS2021) and employs the Mincer earnings function to analyze several main factors, such as years of education (yoe), years of work (yow), education type (et), interaction between edt and yoe and yow, and gender. The results highlight the significant role of education in enhancing both employability and wages—indicating that increased years of education positively correlate with improved employment prospects and higher wages. Regarding the relationship between wages and gender across both education types, males generally receive higher wages, while the dynamics in the relationship between employment and gender differ, with females exhibiting a greater likelihood of employment. The impact of education type on employability is slightly complicated. Employers do not prefer employing general education graduates. However, when we combined education type with years of experience, the findings revealed a preference among employers for hiring general education graduates with extensive work experience. This study has policy implications for the Chinese government in fostering the balanced development of vocational and general education, benefiting both individuals and society.
本文旨在研究中国最近的教育政策对普通教育和职业教育毕业生的劳动力市场表现(即就业能力和工资)的影响。该政策要求 50%的初中毕业生接受中等职业教育。这项政策遭到了公众的投诉,因为在世界许多地方,学生可以自由决定自己未来的教育。本文衡量了教育类型对普通教育和职业教育毕业生劳动力市场表现的影响,试图揭示中国政府和公众之间的不同观点。研究利用《中国社会调查 2021》(CSS2021)的二次调查数据,运用明瑟收益函数分析了几个主要因素,如教育年限(yoe)、工作年限(yow)、教育类型(et)、edt 与 yoe 和 yow 的交互作用以及性别。结果表明,教育年限的增加与就业前景的改善和工资的提高呈正相关。就两种教育类型的工资与性别之间的关系而言,男性通常获得较高的工资,而就业与性别之间的动态关系则有所不同,女性表现出更大的就业可能性。教育类型对就业能力的影响略显复杂。雇主并不倾向于聘用普通教育毕业生。然而,当我们将教育类型与工作年限相结合时,研究结果显示,雇主更倾向于聘用具有丰富工作经验的普通教育毕业生。本研究对中国政府促进职业教育和普通教育均衡发展,造福个人和社会具有政策意义。
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引用次数: 0
Differential impacts of COVID-19 on Indian sectors: Resilience of pharmaceuticals and automobiles, contrasting with negative effects on IT and real estate - An ARIMA-GARCH analysis COVID-19 对印度各行业的不同影响:制药业和汽车业的复原力与 IT 业和房地产业的负面影响形成鲜明对比--ARIMA-GARCH 分析
Pub Date : 2024-02-05 DOI: 10.31893/multiscience.2024140
Debanjalee Bose, Sakthi Srinivasan K.
The COVID-19 pandemic had a profound impact on financial markets worldwide, including those in India, and it has resulted in increased volatility with spillover effects across various industries. This study provides insights into the differential impact of COVID-19 on various industries in India by employing the ARIMA-GARCH model. The study utilized daily data spanning from 2017 to 2023 to examine industry responses during the COVID-19 pandemic, delineating three distinct periods: 2017 to 2021, denoting the pre pandemic era; 2020 to 2023, encompassing the turbulent during-COVID phase; and 2021 to 2023, representing the post-COVID era. In this study, the IT and real estate sectors are considered dependent variables, while the automotive and pharmaceutical sectors are regarded as independent variables. The primary aim is to uncover the complex influence of the IT industry on the automotive, pharmaceutical, and real estate sectors during these time frames; and to elucidate how the real estate industry reciprocally affects these sectors. Our empirical analysis provides insights into the asymmetric transmission mechanism of spillovers. By disentangling overall shocks into macroeconomic impacts affecting all sectors and industrial influences exclusive to specific sectors, we discern that macroeconomic shocks, rather than industrial shocks, primarily dictate the asymmetry in spillover transmission dynamics. This study contributes to a comprehensive understanding of how industries responded to the unprecedented challenges posed by the pandemic, offering valuable insights for strategic decision-making and policy formulation in the post-COVID-19 era.
COVID-19 大流行对包括印度在内的全球金融市场产生了深远影响,并导致波动性增加,对各行各业产生溢出效应。本研究采用 ARIMA-GARCH 模型,深入分析了 COVID-19 对印度各行业的不同影响。研究利用从 2017 年到 2023 年的每日数据来考察 COVID-19 大流行期间的行业反应,划分出三个不同的时期:2017 年到 2021 年,表示大流行前时期;2020 年到 2023 年,包括 COVID 期间的动荡阶段;2021 年到 2023 年,代表 COVID 后时期。在本研究中,IT 和房地产行业被视为因变量,而汽车和制药行业被视为自变量。研究的主要目的是揭示 IT 行业在这些时间段内对汽车、医药和房地产行业的复杂影响,并阐明房地产行业如何对这些行业产生相互影响。我们的实证分析深入揭示了溢出效应的非对称传导机制。通过将整体冲击分解为影响所有行业的宏观经济影响和特定行业独有的产业影响,我们发现宏观经济冲击而非产业冲击是溢出效应非对称传导动态的主要决定因素。这项研究有助于全面了解各行业如何应对大流行病带来的前所未有的挑战,为后 COVID-19 时代的战略决策和政策制定提供了宝贵的见解。
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引用次数: 0
The main causative factor of increased mortality rate in experimental rat 实验大鼠死亡率增加的主要原因
Pub Date : 2024-02-05 DOI: 10.31893/multiscience.2024130
Hala Adnan Abdul-Hameed, Hayder F Saloom
Rats are still often used in vital areas of biological study. Animal management, behavior, compliance and technical processes directly relevant to research projects are just a few of the many duties placed on the shoulders of those conducting such studies. This study was designed to fill a gap in the literature by providing a rapid reference source for researchers and animal care takers responsible for the care and/or usage of rats in research settings, since no prior study has detailed the death rate of experimental rats. A total of 103 adult wister albino rats, aged (12-15) weeks, were included in this study. The rats were subjected to orthodontic treatment using a metal spring coil measuring 6 mm in length, with force of 100 gm. to induce tooth movement. The experimental study involved a total of 56 rats, with 47 rats being excluded from the study due to mortality during the course of the study. The total death rate was determined. The greatest fatality rate was found to be 32%, and it was caused by rats related factors. The anesthetic death rate was 23%. The mortality rate in a controlled laboratory environment was 26%. The lowest cause of death rate was found to be the environmental factors at 19%. To maintain the reliability and repeatability of study results, it is crucial to implement a health monitoring programme for the experimental rat, whose death rate may be significantly impacted by factors such as biological diversity, stress, and an exhausted mechanism.
在生物研究的重要领域中,大鼠仍然经常被使用。与研究项目直接相关的动物管理、行为、合规性和技术流程只是开展此类研究的人员所肩负的众多职责中的一小部分。本研究旨在填补文献空白,为研究人员和负责在研究环境中护理和/或使用大鼠的动物护理人员提供快速参考来源,因为此前没有任何研究详细说明过实验大鼠的死亡率。本研究共纳入 103 只成年紫貂白化大鼠,年龄为(12-15)周。这些大鼠接受了牙齿矫正治疗,使用长度为 6 毫米的金属弹簧圈,施加 100 克的力来诱导牙齿移动。实验研究共涉及 56 只大鼠,其中 47 只大鼠因在研究过程中死亡而被排除在研究之外。总死亡率已确定。发现最大死亡率为 32%,是由与大鼠相关的因素造成的。麻醉死亡率为 23%。在受控实验室环境中的死亡率为 26%。环境因素造成的死亡率最低,为 19%。为了保持研究结果的可靠性和可重复性,对实验鼠实施健康监测计划至关重要,因为实验鼠的死亡率可能会受到生物多样性、压力和衰竭机制等因素的显著影响。
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引用次数: 0
Nurses’ attitudes to care of the elderly 护士对护理老年人的态度
Pub Date : 2024-02-02 DOI: 10.31893/multiscience.2024134
Edona Gara, Selvete Shuleta-Qehaja, Egzona Gara
According to the United Nations most recent figures (2020), the percentage of the people over the age of 65 accounts for 9.31% of the total global population in 2020. This phenomena is expected to have a direct impact on health care services, raising demand and influencing health care workers' attitudes and services for elderly individuals.  The purpose of this study is to analyze nurses' attitudes toward senior care and to identify the associated factors that influence their opinions. The study is of the transverse (cross-sectional) type. Between January and March 2022, 299 nurses were surveyed at four public institutions: the University Clinical Centre, the General Hospital "Dr. Sami Haxhibeqiri" in Mitrovica, the Main Centre of Family Medicine "Dr. Hafir Shala" in Drenas, and the Family Medicine Centre in Komoran. The sample was chosen at random. The majority of the nurses in the survey (86.3%) agree with the statement that they have favorable attitudes toward aged care and that health services are provided qualitatively in the health institutions where the research was performed (76% of respondents). The amount of education of nurses had the greatest impact on the emergence of compliance with positive attitudes, with results showing that nurses with a higher level of education tend to have compliance with more favorable attitudes toward care for elderly individuals. The majority of the nurses who took part in the study believe that they have generally positive views toward aged care and that the provision of nursing care services in their healthcare institutions is of high quality.
根据联合国的最新数据(2020 年),2020 年 65 岁以上人口占全球总人口的 9.31%。这一现象预计将对医疗保健服务产生直接影响,提高需求并影响医护人员对老年人的态度和服务。 本研究旨在分析护士对老年护理的态度,并找出影响其观点的相关因素。本研究为横向(交叉)研究。2022 年 1 月至 3 月期间,299 名护士在四家公共机构接受了调查:大学临床中心、米特罗维察的 "萨米-哈希贝基里博士 "综合医院、德雷纳斯的 "哈菲尔-沙拉博士 "家庭医学主中心和科莫兰的家庭医学中心。样本是随机抽取的。参与调查的大多数护士(86.3%)都同意这样的说法,即她们对老年护理持良好的态度,并且在进行研究的医疗机构中提供的医疗服务是高质量的(76%的受访者)。护士的受教育程度对是否遵从积极态度的影响最大,结果显示,受教育程度较高的护士往往遵从对老年人护理更有利的态度。参与研究的大多数护士认为,他们对老年护理的看法总体上是积极的,他们所在的医疗机构提供的护理服务质量很高。
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引用次数: 0
Reassessment of linkage between stock prices and gold prices: A causal investigation 重新评估股票价格与黄金价格之间的联系:因果关系调查
Pub Date : 2024-02-01 DOI: 10.31893/multiscience.2024122
Tariq Aziz
This research aims to understand the connection between the capital market and the gold market. To understand the link between gold prices and equity prices and vice versa, the vector autoregression model (VAR) is estimated, and the Granger causality test is performed in the framework of VAR. Unit root tests such as the Augment Dicky Fuller test and Phillips-Pierrion test are conducted to check for the stationarity of the data. Johansen's cointegration test is conducted to check for cointegration between two time series. We utilized weekly data from June 7, 2009, to December 25, 2021. Stock indices of three countries, namely, Saudi Arabia, the United Arab Emirates, and Turkey, are used in the paper. Gold prices are in the currency of selected stock markets. According to the findings, unidirectional causality exists only in the case of Turkey, where it runs from stock returns to gold returns. Numerous articles have attempted to clarify the connection between the gold market and stock exchanges. This paper utilizes the most recent data and tries to understand the linkages among three countries that are major buyers of gold.
本研究旨在了解资本市场与黄金市场之间的联系。为了解黄金价格与股票价格之间的联系,以及黄金价格与股票价格之间的反向联系,我们估算了向量自回归模型(VAR),并在 VAR 框架内进行了格兰杰因果关系检验。进行了单位根检验,如 Augment Dicky Fuller 检验和 Phillips-Pierrion 检验,以检查数据的静态性。约翰森协整检验用于检查两个时间序列之间是否存在协整关系。我们使用的是 2009 年 6 月 7 日至 2021 年 12 月 25 日的每周数据。本文使用了沙特阿拉伯、阿拉伯联合酋长国和土耳其三个国家的股票指数。黄金价格以选定股票市场的货币计价。研究结果表明,只有土耳其存在从股票收益到黄金收益的单向因果关系。许多文章都试图阐明黄金市场与股票交易之间的联系。本文利用最新数据,试图了解三个黄金主要买家国家之间的联系。
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引用次数: 0
Evaluation of guideline-concordant treatment and clinical outcomes in non-small cell lung cancer: A study at a National-Referral Hospital in Indonesia 评估非小细胞肺癌的指南一致性治疗和临床疗效:印度尼西亚一家国家转诊医院的研究
Pub Date : 2024-02-01 DOI: 10.31893/multiscience.2024131
Diaza Okadimar Ariyanto, Sigit Wirawan, E. A. Pangarsa, Fathur Nur Kholis, Muhammad Ali Shodiq, C. Prihharsanti
Non-adherence to guidelines has been demonstrated to affect clinical outcomes. With more than half of the global incidence of lung cancer occurring in Asia, this study aims to evaluate the guideline-concordant treatment (GCT) among Asian patients based on the 2018 NCCN-Asia consensus statements on NSCLC. Patients diagnosed with NSCLC between December 2018 and 2019 were identified from electronic medical records. Patients with complete data were divided into GCT-positive and negative groups. Statistical analyses were performed to analyze survival distributions and the associations between covariates and GCT status. Out of 50 patients, 90% were in stage IV. No patients underwent PET scans nor stereotactic radiotherapy due to the absence of facilities. Overall, 44% of patients were GCT-positive. Most GCT-negative patients did not receive chemotherapy due to poor performance scores. There was a significant difference in the survival distribution between groups (72.7% vs 39.3%, p=0.006). Age and sex were not significantly associated with GCT status (p>0.05). After accounting for other covariates including histology, GCT-negative was still associated with an increased hazard of all-cause mortality (HR 3.07 [1.15-8.12]; p=0.025). Despite limitations, concordance with Asian-specific guidelines independently and significantly improved OS among patients at a national-referral hospital in Indonesia.
事实证明,不遵守指南会影响临床结果。由于全球一半以上的肺癌发病率发生在亚洲,本研究旨在根据2018年NCCN-Asia关于NSCLC的共识声明,评估亚洲患者的指南一致性治疗(GCT)情况。研究人员从电子病历中找到了 2018 年 12 月至 2019 年期间确诊为 NSCLC 的患者。数据完整的患者被分为GCT阳性组和阴性组。研究人员进行了统计分析,以分析生存率分布以及协变量与GCT状态之间的关联。在50名患者中,90%处于IV期。由于缺乏设施,没有患者接受正电子发射计算机断层扫描或立体定向放射治疗。总体而言,44% 的患者为 GCT 阳性。大多数 GCT 阴性患者因表现评分不佳而未接受化疗。两组患者的存活率分布有明显差异(72.7% vs 39.3%,P=0.006)。年龄和性别与 GCT 状态无明显相关性(P>0.05)。在考虑了组织学等其他协变量后,GCT 阴性仍与全因死亡率增加有关(HR 3.07 [1.15-8.12]; p=0.025)。尽管存在局限性,但在印度尼西亚的一家国家转诊医院中,与亚洲特定指南保持一致可独立且显著地改善患者的OS。
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引用次数: 0
The influence of project-based learning and problem-based learning models on science learning ability from the perspectives of learning interest 从学习兴趣的角度看项目式学习和问题式学习模式对科学学习能力的影响
Pub Date : 2024-02-01 DOI: 10.31893/multiscience.2024137
M. Husna, Sudiyanto, P. Rintayati
This research aimed to: (1) determine differences in science learning abilities between students taught using the project-based learning and problem-based learning models; (2) determine differences in science learning abilities between students who had high learning interest and those who had low learning interest; and (3) determine the interaction between learning models and learning interest on science learning abilities. This research was quantitative research with a quasi experimental type carried out in two sub districts: Pasarkliwon Sub district and Banjarsari Sub district. The research samples were sixth-grade students at Carangan State Elementary School in Pasar Kliwon Sub district as the experimental group and Purworejo State Elementary School, Banjarsari Sub district as the control group. Data collection techniques used test and non test techniques (questionnaires). The data analysis technique used Two Way Analysis of Variance using a significance level of α = 0.05. The results of the research showed that there were differences in students' understanding abilities with a significance level of 0.00<0.05 in project-based learning model learning and problem-based learning. There was a difference in the ability to understand solar system material with a significance level of 0.00<0.05 between students who had a high interest in learning and students who had a low interest in learning. There was an interaction between the learning model and learning interest indicated by (α) 0.003<0.05. Therefore, it can be concluded that the application of learning models and students' learning interests influenced students' ability to understand solar system materials.
本研究旨在(1) 确定采用基于项目的学习模式和基于问题的学习模式教学的学生在科学学习能力上的差异;(2) 确定学习兴趣高的学生和学习兴趣低的学生在科学学习能力上的差异;以及 (3) 确定学习模式和学习兴趣对科学学习能力的交互作用。本研究是在两个分区开展的准实验型定量研究:研究样本为六年级学生。研究样本分别为实验组(Pasar Kliwon 分区 Carangan 州立小学六年级学生)和对照组(Banjarsari 分区 Purworejo 州立小学)。数据收集技术采用了测试和非测试技术(问卷调查)。数据分析技术采用了双向方差分析,显著性水平为 α = 0.05。研究结果表明,在基于项目的学习模式学习和基于问题的学习中,学生的理解能力存在差异,显著性水平为 0.00<0.05。学习兴趣高的学生和学习兴趣低的学生对太阳系材料的理解能力存在差异,显著性水平为 0.00<0.05。学习模式与学习兴趣之间存在交互作用,其显著性水平为(α)0.003<0.05。因此,可以得出结论:学习模式的应用和学生的学习兴趣影响了学生理解太阳系教材的能力。
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Multidisciplinary Science Journal
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