THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019最新文献
The study aimed to observe the function of vacuum clamp as gripping equipment for the cutting process of the aluminum plate using PC-based CNC milling equipment as well as to find out an optimum suction pressure of the vacuum clamp and the effect on the surface roughness of the aluminum plate after the cutting process. The cutting process of the aluminum plates utilized a PC-based CNC milling equipment with a vacuum clamp as its gripping equipment in the form of a cutter-end mill HSS with a 3 mm diameter and 1.7 mm aluminum plate (Al 1100) thickness as workpieces. The sealing of the gripping equipment utilized a rubber mat in a 1.7 mm thickness. The milling process was set up at 2,650 rpm of the spindle rotation speed, 32 mm/minute feeding speed, 0.2 mm depth of cut, and 0.007 mm/tooth feed rate. The surface roughness of the outcome was measured using a Profilometer. The suction pressure of the vacuum pump was controlled by the valve and control tube, thus could maintain a stable suction pressure during the machinery process. The suction pressure varied from -18 inHg, -20 inHg, -22 inHg, and -24 inHg. The findings indicated that the cutting process of the aluminum plate using vacuum clamp as gripping equipment at -24 inHg of suction pressure was able to produce surface roughness (Ra) according to the standard of limit as determined in Part 2 of DIN.The study aimed to observe the function of vacuum clamp as gripping equipment for the cutting process of the aluminum plate using PC-based CNC milling equipment as well as to find out an optimum suction pressure of the vacuum clamp and the effect on the surface roughness of the aluminum plate after the cutting process. The cutting process of the aluminum plates utilized a PC-based CNC milling equipment with a vacuum clamp as its gripping equipment in the form of a cutter-end mill HSS with a 3 mm diameter and 1.7 mm aluminum plate (Al 1100) thickness as workpieces. The sealing of the gripping equipment utilized a rubber mat in a 1.7 mm thickness. The milling process was set up at 2,650 rpm of the spindle rotation speed, 32 mm/minute feeding speed, 0.2 mm depth of cut, and 0.007 mm/tooth feed rate. The surface roughness of the outcome was measured using a Profilometer. The suction pressure of the vacuum pump was controlled by the valve and control tube, thus could maintain a stable suction pressure during t...
{"title":"The effect of suction pressure of vacuum clamp on the aluminum plate surface following the cutting process using mini PC-based CNC milling","authors":"Karnova Yanel, Herianto, R. Sriwijaya","doi":"10.1063/1.5138349","DOIUrl":"https://doi.org/10.1063/1.5138349","url":null,"abstract":"The study aimed to observe the function of vacuum clamp as gripping equipment for the cutting process of the aluminum plate using PC-based CNC milling equipment as well as to find out an optimum suction pressure of the vacuum clamp and the effect on the surface roughness of the aluminum plate after the cutting process. The cutting process of the aluminum plates utilized a PC-based CNC milling equipment with a vacuum clamp as its gripping equipment in the form of a cutter-end mill HSS with a 3 mm diameter and 1.7 mm aluminum plate (Al 1100) thickness as workpieces. The sealing of the gripping equipment utilized a rubber mat in a 1.7 mm thickness. The milling process was set up at 2,650 rpm of the spindle rotation speed, 32 mm/minute feeding speed, 0.2 mm depth of cut, and 0.007 mm/tooth feed rate. The surface roughness of the outcome was measured using a Profilometer. The suction pressure of the vacuum pump was controlled by the valve and control tube, thus could maintain a stable suction pressure during the machinery process. The suction pressure varied from -18 inHg, -20 inHg, -22 inHg, and -24 inHg. The findings indicated that the cutting process of the aluminum plate using vacuum clamp as gripping equipment at -24 inHg of suction pressure was able to produce surface roughness (Ra) according to the standard of limit as determined in Part 2 of DIN.The study aimed to observe the function of vacuum clamp as gripping equipment for the cutting process of the aluminum plate using PC-based CNC milling equipment as well as to find out an optimum suction pressure of the vacuum clamp and the effect on the surface roughness of the aluminum plate after the cutting process. The cutting process of the aluminum plates utilized a PC-based CNC milling equipment with a vacuum clamp as its gripping equipment in the form of a cutter-end mill HSS with a 3 mm diameter and 1.7 mm aluminum plate (Al 1100) thickness as workpieces. The sealing of the gripping equipment utilized a rubber mat in a 1.7 mm thickness. The milling process was set up at 2,650 rpm of the spindle rotation speed, 32 mm/minute feeding speed, 0.2 mm depth of cut, and 0.007 mm/tooth feed rate. The surface roughness of the outcome was measured using a Profilometer. The suction pressure of the vacuum pump was controlled by the valve and control tube, thus could maintain a stable suction pressure during t...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73674864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
World Health Organization (WHO) data stated that heart diseases cause 37% of deaths in Indonesia. In Indonesia, devices used to monitor the heart’s activity or electrocardiogram (ECG) are only owned by some big hospitals. With an Arduino microprocessor, a simple portable ECG with a function to read the heart’s condition could be made. The AD8232 sensor is the main device that is used to read the heartbeat by processing the voltage received from the electrodes attached to the body. Combination of Arduino-Uno and HC-05 FC-114 as a Bluetooth antenna, an ECG display could be seen on a smartphone’s monitor in real-time. An ECG simulator is used as an artificial heart activity to be used as a trial for the ECG portable’s performance from test results. ECG using the simulator can be delivered to the smartphone’s monitor by Bluetooth module with an accurate result that draws the real-time condition of the patients.World Health Organization (WHO) data stated that heart diseases cause 37% of deaths in Indonesia. In Indonesia, devices used to monitor the heart’s activity or electrocardiogram (ECG) are only owned by some big hospitals. With an Arduino microprocessor, a simple portable ECG with a function to read the heart’s condition could be made. The AD8232 sensor is the main device that is used to read the heartbeat by processing the voltage received from the electrodes attached to the body. Combination of Arduino-Uno and HC-05 FC-114 as a Bluetooth antenna, an ECG display could be seen on a smartphone’s monitor in real-time. An ECG simulator is used as an artificial heart activity to be used as a trial for the ECG portable’s performance from test results. ECG using the simulator can be delivered to the smartphone’s monitor by Bluetooth module with an accurate result that draws the real-time condition of the patients.
{"title":"Prototype low-cost portable electrocardiogram (ECG) based on Arduino-Uno with Bluetooth feature","authors":"William Jerrel Iskandar, Ibnu Roihan, R. Koestoer","doi":"10.1063/1.5139392","DOIUrl":"https://doi.org/10.1063/1.5139392","url":null,"abstract":"World Health Organization (WHO) data stated that heart diseases cause 37% of deaths in Indonesia. In Indonesia, devices used to monitor the heart’s activity or electrocardiogram (ECG) are only owned by some big hospitals. With an Arduino microprocessor, a simple portable ECG with a function to read the heart’s condition could be made. The AD8232 sensor is the main device that is used to read the heartbeat by processing the voltage received from the electrodes attached to the body. Combination of Arduino-Uno and HC-05 FC-114 as a Bluetooth antenna, an ECG display could be seen on a smartphone’s monitor in real-time. An ECG simulator is used as an artificial heart activity to be used as a trial for the ECG portable’s performance from test results. ECG using the simulator can be delivered to the smartphone’s monitor by Bluetooth module with an accurate result that draws the real-time condition of the patients.World Health Organization (WHO) data stated that heart diseases cause 37% of deaths in Indonesia. In Indonesia, devices used to monitor the heart’s activity or electrocardiogram (ECG) are only owned by some big hospitals. With an Arduino microprocessor, a simple portable ECG with a function to read the heart’s condition could be made. The AD8232 sensor is the main device that is used to read the heartbeat by processing the voltage received from the electrodes attached to the body. Combination of Arduino-Uno and HC-05 FC-114 as a Bluetooth antenna, an ECG display could be seen on a smartphone’s monitor in real-time. An ECG simulator is used as an artificial heart activity to be used as a trial for the ECG portable’s performance from test results. ECG using the simulator can be delivered to the smartphone’s monitor by Bluetooth module with an accurate result that draws the real-time condition of the patients.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75097642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vortices phenomenon becomes one of solutions to enhance heat transfer performance in shell-and-tube type of heat exchanger. Vortex generator is a device that can generate moving vortices of fluid to get good mixing fluid in heat transfer. The aim of this study is to find the effect of rectangular and delta winglet vortex generator if they are applied in inner tubular pipe heat exchanger, especially for shell-and-tube heat exchanger. Two types of winglet vortex generator were mounted in inner circular pipe then examined in turbulent flow with 6000-10000 Reynold numbers. The result of simulation showed that the use of rectangular and delta winglet can improve heat transfer performance.
{"title":"Flow structure investigation heat transfer enhancement on inner tubular pipe with winglet vortex generator","authors":"Stefan Mardikus, Malfin, I. Ekaputra","doi":"10.1063/1.5138292","DOIUrl":"https://doi.org/10.1063/1.5138292","url":null,"abstract":"Vortices phenomenon becomes one of solutions to enhance heat transfer performance in shell-and-tube type of heat exchanger. Vortex generator is a device that can generate moving vortices of fluid to get good mixing fluid in heat transfer. The aim of this study is to find the effect of rectangular and delta winglet vortex generator if they are applied in inner tubular pipe heat exchanger, especially for shell-and-tube heat exchanger. Two types of winglet vortex generator were mounted in inner circular pipe then examined in turbulent flow with 6000-10000 Reynold numbers. The result of simulation showed that the use of rectangular and delta winglet can improve heat transfer performance.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76498398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Supriadi, Mohamad Fadhil Ardianov, A. Rahyussalim, Y. Whulanza, Yogi Prabowo, A. S. Saragih
{"title":"Evaluating internal forces of new design modular MegaProsthesis distal femur","authors":"S. Supriadi, Mohamad Fadhil Ardianov, A. Rahyussalim, Y. Whulanza, Yogi Prabowo, A. S. Saragih","doi":"10.1063/1.5139398","DOIUrl":"https://doi.org/10.1063/1.5139398","url":null,"abstract":"","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84009058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sugiharto, F. Ferryanto, Harridhi Dzar Tazakka, A. Mahyuddin, A. Wibowo, S. Mihradi
In this study, structural analysis of energy storage and return (ESAR) prosthetic foot was carried out by using the finite element method. The basic design of the ESAR prosthetic foot consists of four main components: main plate, S-plate, base plate, and auxiliary body. SOLIDWORKS was used for modeling of ESAR prosthetic foot during the design stage. Furthermore, an ANSYS Workbench 16.2 was used to perform a finite element analysis of ESAR prosthetics foot structure. Static simulation is carried out with a loading force of 750 N representing the amount of force that is supported by the edge of the base-plate component during the push-off phase. In the initial design, the maximum stress that occurs during the static loading is 353.96 MPa, exceeding the yield strength of aluminum 6061 of 276 MPa. Hence, to alleviate the exceedingly high maximum stress, three alternative structural reinforcement types are considered for a design modification. The version of reinforcement yielding the smallest maximum stress was selected in the design modification of ESAR prosthetic foot to be used in the robotic prosthetics ankle. The equivalent stiffness of the final ESAR prosthetic foot design has been calculated to be used in the control system scheme.In this study, structural analysis of energy storage and return (ESAR) prosthetic foot was carried out by using the finite element method. The basic design of the ESAR prosthetic foot consists of four main components: main plate, S-plate, base plate, and auxiliary body. SOLIDWORKS was used for modeling of ESAR prosthetic foot during the design stage. Furthermore, an ANSYS Workbench 16.2 was used to perform a finite element analysis of ESAR prosthetics foot structure. Static simulation is carried out with a loading force of 750 N representing the amount of force that is supported by the edge of the base-plate component during the push-off phase. In the initial design, the maximum stress that occurs during the static loading is 353.96 MPa, exceeding the yield strength of aluminum 6061 of 276 MPa. Hence, to alleviate the exceedingly high maximum stress, three alternative structural reinforcement types are considered for a design modification. The version of reinforcement yielding the smallest maximum stress ...
本研究采用有限元法对ESAR (energy storage and return)假肢足进行结构分析。ESAR假肢足的基本设计由四个主要部件组成:主板、s板、底板和辅助体。ESAR假肢足在设计阶段采用SOLIDWORKS进行建模。利用ANSYS Workbench 16.2对ESAR义肢足部结构进行有限元分析。静态模拟以750 N的加载力进行，该加载力表示在推离阶段由底板组件边缘所支持的力的大小。在初始设计中，静加载时产生的最大应力为353.96 MPa，超过了6061铝的屈服强度276 MPa。因此，为了减轻极高的最大应力，三种可供选择的结构加固类型被考虑用于设计修改。在ESAR假肢足的设计修改中，选择最大应力最小的加固版本用于机器人假肢踝关节。计算了ESAR假肢足最终设计的等效刚度，用于控制系统方案。本研究采用有限元法对ESAR (energy storage and return)假肢足进行结构分析。ESAR假肢足的基本设计由四个主要部件组成:主板、s板、底板和辅助体。ESAR假肢足在设计阶段采用SOLIDWORKS进行建模。利用ANSYS Workbench 16.2对ESAR义肢足部结构进行有限元分析。静态模拟以750 N的加载力进行，该加载力表示在推离阶段由底板组件边缘所支持的力的大小。在初始设计中，静加载时产生的最大应力为353.96 MPa，超过了6061铝的屈服强度276 MPa。因此，为了减轻极高的最大应力，三种可供选择的结构加固类型被考虑用于设计修改。产生最小最大应力的钢筋版本…
{"title":"Static analysis of an energy storage and return (ESAR) prosthetic foot","authors":"A. Sugiharto, F. Ferryanto, Harridhi Dzar Tazakka, A. Mahyuddin, A. Wibowo, S. Mihradi","doi":"10.1063/1.5139380","DOIUrl":"https://doi.org/10.1063/1.5139380","url":null,"abstract":"In this study, structural analysis of energy storage and return (ESAR) prosthetic foot was carried out by using the finite element method. The basic design of the ESAR prosthetic foot consists of four main components: main plate, S-plate, base plate, and auxiliary body. SOLIDWORKS was used for modeling of ESAR prosthetic foot during the design stage. Furthermore, an ANSYS Workbench 16.2 was used to perform a finite element analysis of ESAR prosthetics foot structure. Static simulation is carried out with a loading force of 750 N representing the amount of force that is supported by the edge of the base-plate component during the push-off phase. In the initial design, the maximum stress that occurs during the static loading is 353.96 MPa, exceeding the yield strength of aluminum 6061 of 276 MPa. Hence, to alleviate the exceedingly high maximum stress, three alternative structural reinforcement types are considered for a design modification. The version of reinforcement yielding the smallest maximum stress was selected in the design modification of ESAR prosthetic foot to be used in the robotic prosthetics ankle. The equivalent stiffness of the final ESAR prosthetic foot design has been calculated to be used in the control system scheme.In this study, structural analysis of energy storage and return (ESAR) prosthetic foot was carried out by using the finite element method. The basic design of the ESAR prosthetic foot consists of four main components: main plate, S-plate, base plate, and auxiliary body. SOLIDWORKS was used for modeling of ESAR prosthetic foot during the design stage. Furthermore, an ANSYS Workbench 16.2 was used to perform a finite element analysis of ESAR prosthetics foot structure. Static simulation is carried out with a loading force of 750 N representing the amount of force that is supported by the edge of the base-plate component during the push-off phase. In the initial design, the maximum stress that occurs during the static loading is 353.96 MPa, exceeding the yield strength of aluminum 6061 of 276 MPa. Hence, to alleviate the exceedingly high maximum stress, three alternative structural reinforcement types are considered for a design modification. The version of reinforcement yielding the smallest maximum stress ...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72828751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. W. Damayanti, M. Sahlan, Kenny Lischer, H. Hermansyah, B. Kusumoputro, D. Pratami
Honey is a liquid produced by bees from nectar which contains vitamins, acids, minerals, and enzymes that are useful for the human body because honey is very beneficial, it can be used as an alternative medicine for human’s healthiness. Authentication of honey has primary importance for both industries and consumers because until now, there is no guarantee of honey’s authenticity especially in Indonesia. As for the classification of honey bees, is based on the fact that the content of honey produced between Apis sp. and stingless bees (most widely harvested honey bees in Indonesia) have differences depending on the type of honey-producing bee, nectar, geographical location, temperature, etc. In this study, the authors tested samples of original honey and fake honey using Gas Chromatography-Mass Spectrometry (GCMS), because GCMS has more accurate results than another test equipment. From this research, the authors obtained compounds that became marker or differentiators between the original honey Apis melifera, A.dorsata, A.cerana and also from fake honey samples (Original honey added with melted fructose and NaHCO3). So that we can find out the possibility of the origin of producing bees and the authenticity of honey by looking at the components contained in honey. The results from this research are Honey from Tetragonula sp species and fake honey have several components of different compounds with honey from Apis sp. Compounds that can be a difference between original and fake honey are ethanol and carbon dioxide.
{"title":"Comparison of original honey (Apis sp and Tetragonula sp) and fake honey compounds in Indonesia using gas chromatography-mass spectrometry (GC-MS)","authors":"N. W. Damayanti, M. Sahlan, Kenny Lischer, H. Hermansyah, B. Kusumoputro, D. Pratami","doi":"10.1063/1.5139355","DOIUrl":"https://doi.org/10.1063/1.5139355","url":null,"abstract":"Honey is a liquid produced by bees from nectar which contains vitamins, acids, minerals, and enzymes that are useful for the human body because honey is very beneficial, it can be used as an alternative medicine for human’s healthiness. Authentication of honey has primary importance for both industries and consumers because until now, there is no guarantee of honey’s authenticity especially in Indonesia. As for the classification of honey bees, is based on the fact that the content of honey produced between Apis sp. and stingless bees (most widely harvested honey bees in Indonesia) have differences depending on the type of honey-producing bee, nectar, geographical location, temperature, etc. In this study, the authors tested samples of original honey and fake honey using Gas Chromatography-Mass Spectrometry (GCMS), because GCMS has more accurate results than another test equipment. From this research, the authors obtained compounds that became marker or differentiators between the original honey Apis melifera, A.dorsata, A.cerana and also from fake honey samples (Original honey added with melted fructose and NaHCO3). So that we can find out the possibility of the origin of producing bees and the authenticity of honey by looking at the components contained in honey. The results from this research are Honey from Tetragonula sp species and fake honey have several components of different compounds with honey from Apis sp. Compounds that can be a difference between original and fake honey are ethanol and carbon dioxide.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72845428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. D. Widiawaty, A. I. Siswantara, Budiarso, A. Daryus, G. Gunadi, H. Pujowidodo
{"title":"Investigation the effect of superficial velocity to the heat transfer in bubbling regime of fluidization using CFD simulation","authors":"C. D. Widiawaty, A. I. Siswantara, Budiarso, A. Daryus, G. Gunadi, H. Pujowidodo","doi":"10.1063/1.5138279","DOIUrl":"https://doi.org/10.1063/1.5138279","url":null,"abstract":"","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81745068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Krisnamurti, F. Sinuraya, Tamara Ey Firsty, Rani Wardani Hakim, E. Purwaningsih
Diet with high fructose and cholesterol (HFHC) plays a role in the increasing incidence of diabetes mellitus and metabolic syndrome. Ethanol extract from Acalypha indica has been known to alleviate hyperglycemia and hyperuricemic conditions in rats induced by substances that destroy beta cells. This research aimed to evaluate its effect in rats induced by diet. Male Sprague-Dawley rats were divided into seven groups, six of which are given HFHC diet for 1,5 months. In the following month, rats were given therapy while diet continued. Therapy consisted of 250 mg/kg BW/day of Acalypha indica Linn. root’s ethanol extract, 100 mg/kgBW/day of metformin, 30mg/kg BW/day of allopurinol, or combination. Lowest blood glucose value was found in group receiving both AI and metformin. No significant difference was found between pre- and post- therapy blood glucose in groups treated with AI (p=0,831), metformin (p=0,056), or both (p=0,908). Uric acid level was increased in all groups, with highest rate found in group receiving both allopurinol and AI. The difference in uric acid level between treatment group was 0.331. Whilst insignificant, ethanolic extract of Acalypha indica Linn. was observed to lower blood glucose in rats. Group treated with AI showed similar rise in uric acid level, with combination therapy showed highest rise. Further research with longer duration of induction and therapy will be required to better understand the hypoglycemic and antihyperuricemic effects exerted by AI.Diet with high fructose and cholesterol (HFHC) plays a role in the increasing incidence of diabetes mellitus and metabolic syndrome. Ethanol extract from Acalypha indica has been known to alleviate hyperglycemia and hyperuricemic conditions in rats induced by substances that destroy beta cells. This research aimed to evaluate its effect in rats induced by diet. Male Sprague-Dawley rats were divided into seven groups, six of which are given HFHC diet for 1,5 months. In the following month, rats were given therapy while diet continued. Therapy consisted of 250 mg/kg BW/day of Acalypha indica Linn. root’s ethanol extract, 100 mg/kgBW/day of metformin, 30mg/kg BW/day of allopurinol, or combination. Lowest blood glucose value was found in group receiving both AI and metformin. No significant difference was found between pre- and post- therapy blood glucose in groups treated with AI (p=0,831), metformin (p=0,056), or both (p=0,908). Uric acid level was increased in all groups, with highest rate found in group r...
{"title":"Uric acid and glucose level in high fructose high cholesterol induced Sprague-Dawley rats after therapy with Acalypha indica Linn. ethanol extract","authors":"D. Krisnamurti, F. Sinuraya, Tamara Ey Firsty, Rani Wardani Hakim, E. Purwaningsih","doi":"10.1063/1.5139351","DOIUrl":"https://doi.org/10.1063/1.5139351","url":null,"abstract":"Diet with high fructose and cholesterol (HFHC) plays a role in the increasing incidence of diabetes mellitus and metabolic syndrome. Ethanol extract from Acalypha indica has been known to alleviate hyperglycemia and hyperuricemic conditions in rats induced by substances that destroy beta cells. This research aimed to evaluate its effect in rats induced by diet. Male Sprague-Dawley rats were divided into seven groups, six of which are given HFHC diet for 1,5 months. In the following month, rats were given therapy while diet continued. Therapy consisted of 250 mg/kg BW/day of Acalypha indica Linn. root’s ethanol extract, 100 mg/kgBW/day of metformin, 30mg/kg BW/day of allopurinol, or combination. Lowest blood glucose value was found in group receiving both AI and metformin. No significant difference was found between pre- and post- therapy blood glucose in groups treated with AI (p=0,831), metformin (p=0,056), or both (p=0,908). Uric acid level was increased in all groups, with highest rate found in group receiving both allopurinol and AI. The difference in uric acid level between treatment group was 0.331. Whilst insignificant, ethanolic extract of Acalypha indica Linn. was observed to lower blood glucose in rats. Group treated with AI showed similar rise in uric acid level, with combination therapy showed highest rise. Further research with longer duration of induction and therapy will be required to better understand the hypoglycemic and antihyperuricemic effects exerted by AI.Diet with high fructose and cholesterol (HFHC) plays a role in the increasing incidence of diabetes mellitus and metabolic syndrome. Ethanol extract from Acalypha indica has been known to alleviate hyperglycemia and hyperuricemic conditions in rats induced by substances that destroy beta cells. This research aimed to evaluate its effect in rats induced by diet. Male Sprague-Dawley rats were divided into seven groups, six of which are given HFHC diet for 1,5 months. In the following month, rats were given therapy while diet continued. Therapy consisted of 250 mg/kg BW/day of Acalypha indica Linn. root’s ethanol extract, 100 mg/kgBW/day of metformin, 30mg/kg BW/day of allopurinol, or combination. Lowest blood glucose value was found in group receiving both AI and metformin. No significant difference was found between pre- and post- therapy blood glucose in groups treated with AI (p=0,831), metformin (p=0,056), or both (p=0,908). Uric acid level was increased in all groups, with highest rate found in group r...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87948494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decrease expressions of ARID1A in non-atypical, atypical endometriosis cyst and ovarian clear cell carcinoma as a biomarker of malignancy transformations","authors":"R. Widyawati, Budiningsih Siregar, K. Kusmardi","doi":"10.1063/1.5139372","DOIUrl":"https://doi.org/10.1063/1.5139372","url":null,"abstract":"","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82875671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedicle screw has a role in stabilizing vertebral bone motion and resisting all types of load such as axially load. If pedicle screw cannot maintain axially load that happened, pull out failure can be occurred. Experimental pedicle screw pull out testing is referring to American Society for Testing and Materials (ASTM) F543. Each pedicle screw displaced at 5 mm/min until pedicle screw pulled from the test block material. Note the displacement graph between load and displacement, and the highest peak means maximum pull out force of the specimen. The purpose of this study to determine the maximum axially force of pedicle screws can bear. Commercial 1 pedicle screw shows higher pull out maximum force with 1497 N than commercial two pedicle screw with 469 N.Pedicle screw has a role in stabilizing vertebral bone motion and resisting all types of load such as axially load. If pedicle screw cannot maintain axially load that happened, pull out failure can be occurred. Experimental pedicle screw pull out testing is referring to American Society for Testing and Materials (ASTM) F543. Each pedicle screw displaced at 5 mm/min until pedicle screw pulled from the test block material. Note the displacement graph between load and displacement, and the highest peak means maximum pull out force of the specimen. The purpose of this study to determine the maximum axially force of pedicle screws can bear. Commercial 1 pedicle screw shows higher pull out maximum force with 1497 N than commercial two pedicle screw with 469 N.
{"title":"Comparative study of commercial pedicle screw based on maximum pull out force","authors":"Radhi Maladzi, S. Supriadi","doi":"10.1063/1.5139337","DOIUrl":"https://doi.org/10.1063/1.5139337","url":null,"abstract":"Pedicle screw has a role in stabilizing vertebral bone motion and resisting all types of load such as axially load. If pedicle screw cannot maintain axially load that happened, pull out failure can be occurred. Experimental pedicle screw pull out testing is referring to American Society for Testing and Materials (ASTM) F543. Each pedicle screw displaced at 5 mm/min until pedicle screw pulled from the test block material. Note the displacement graph between load and displacement, and the highest peak means maximum pull out force of the specimen. The purpose of this study to determine the maximum axially force of pedicle screws can bear. Commercial 1 pedicle screw shows higher pull out maximum force with 1497 N than commercial two pedicle screw with 469 N.Pedicle screw has a role in stabilizing vertebral bone motion and resisting all types of load such as axially load. If pedicle screw cannot maintain axially load that happened, pull out failure can be occurred. Experimental pedicle screw pull out testing is referring to American Society for Testing and Materials (ASTM) F543. Each pedicle screw displaced at 5 mm/min until pedicle screw pulled from the test block material. Note the displacement graph between load and displacement, and the highest peak means maximum pull out force of the specimen. The purpose of this study to determine the maximum axially force of pedicle screws can bear. Commercial 1 pedicle screw shows higher pull out maximum force with 1497 N than commercial two pedicle screw with 469 N.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84657620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019
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