OBJECTIVE To evaluate the change in demineralisation depth (DD)and mineral density (MD) over time in primary teeth exposed to a demineralisation protocol with microcomputed tomography (microCT). METHODS Caries lesions were artificially induced on the labial surfaces of 9 primary incisors by way of a demineralisation protocol using 0.1 M lactic acid with 10% methylcellulose gel for 7 and 14 days. The specimens were scanned with microCT and CTAn software (Bruker, Billerica, MA, USA) was used to analyse the changes in DD and MD. Statistical analyses were performed using SPSS software (IBM, Armonk, NY, USA). Repeated analysis of variance (ANOVA) test and Pearson bivariate correlation were used and the level of significance was set at P < 0.05. RESULTS The DD ranged from 0.00 to 0.99 μm (mean ± standard deviation [SD] 0.70 ± 0.43 μm) at baseline, 11.18 to 29.5 μm (18.15 ± 5.23 μm) at 7 days and 18.00 to 55.30 μm (34.20 ± 8.70 μm) at 14 days. The MD for all specimens (n = 9) ranged from 1.48 to 1.76 g/cm3 (1.65 ± 0.08 g/cm3) at baseline, from 1.47 to 1.74 g/cm3 (1.62 ± 0.08 g/cm3) at 7 days demineralisation and 1.33 to 1.72 g/cm3 (1.54 ± 0.13 g/cm3) at 14 days. There were statistically significant differences in DD (P < 0.001) and MD (P = 0.016) between different durations of demineralisation. CONCLUSION DD and MD change with time after being exposed to demineralising solution. MicroCT is a nondestructive method that allows repeated MD evaluations of the same sample.
{"title":"A MicroCT Study on Mineral Change over Time Associated with Demineralisation in Primary Teeth.","authors":"K. Wu, Jung-Wei Chen, S. Kwon","doi":"10.3290/j.cjdr.b3086347","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086347","url":null,"abstract":"OBJECTIVE\u0000To evaluate the change in demineralisation depth (DD)and mineral density (MD) over time in primary teeth exposed to a demineralisation protocol with microcomputed tomography (microCT).\u0000\u0000\u0000METHODS\u0000Caries lesions were artificially induced on the labial surfaces of 9 primary incisors by way of a demineralisation protocol using 0.1 M lactic acid with 10% methylcellulose gel for 7 and 14 days. The specimens were scanned with microCT and CTAn software (Bruker, Billerica, MA, USA) was used to analyse the changes in DD and MD. Statistical analyses were performed using SPSS software (IBM, Armonk, NY, USA). Repeated analysis of variance (ANOVA) test and Pearson bivariate correlation were used and the level of significance was set at P < 0.05.\u0000\u0000\u0000RESULTS\u0000The DD ranged from 0.00 to 0.99 μm (mean ± standard deviation [SD] 0.70 ± 0.43 μm) at baseline, 11.18 to 29.5 μm (18.15 ± 5.23 μm) at 7 days and 18.00 to 55.30 μm (34.20 ± 8.70 μm) at 14 days. The MD for all specimens (n = 9) ranged from 1.48 to 1.76 g/cm3 (1.65 ± 0.08 g/cm3) at baseline, from 1.47 to 1.74 g/cm3 (1.62 ± 0.08 g/cm3) at 7 days demineralisation and 1.33 to 1.72 g/cm3 (1.54 ± 0.13 g/cm3) at 14 days. There were statistically significant differences in DD (P < 0.001) and MD (P = 0.016) between different durations of demineralisation.\u0000\u0000\u0000CONCLUSION\u0000DD and MD change with time after being exposed to demineralising solution. MicroCT is a nondestructive method that allows repeated MD evaluations of the same sample.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"7 1","pages":"125-130"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87545509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Atarbashi-Moghadam, M. Rezai Rad, S. Sijanivandi, P. Khodayari, Masoumeh Mahmoum
The ultimate goal of periodontal treatments is the regeneration of all lost periodontal tissues including bone, cementum and the periodontal ligament (PDL). Until now, the clinical methods for periodontal regeneration have been associated with significant failure or incomplete success. Various studies have reported the promising effects of growth factors/cytokines on periodontal regeneration. Growth factors/cytokines include proteins or steroid hormones that bind to cellular receptors, known as signalling molecules, and that trigger cellular responses that eventually stimulate cell proliferation and differentiation. The present review aims to provide an overview of the main growth factors that play an important role in and have been used in the regeneration of periodontal components.
{"title":"Growth Factors in Periodontal Complex Regeneration.","authors":"F. Atarbashi-Moghadam, M. Rezai Rad, S. Sijanivandi, P. Khodayari, Masoumeh Mahmoum","doi":"10.3290/j.cjdr.b3086335","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086335","url":null,"abstract":"The ultimate goal of periodontal treatments is the regeneration of all lost periodontal tissues including bone, cementum and the periodontal ligament (PDL). Until now, the clinical methods for periodontal regeneration have been associated with significant failure or incomplete success. Various studies have reported the promising effects of growth factors/cytokines on periodontal regeneration. Growth factors/cytokines include proteins or steroid hormones that bind to cellular receptors, known as signalling molecules, and that trigger cellular responses that eventually stimulate cell proliferation and differentiation. The present review aims to provide an overview of the main growth factors that play an important role in and have been used in the regeneration of periodontal components.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"26 1","pages":"85-92"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87941719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jing Wang, J. Gu, M. Meng, Chen Wang, Ji Hua Chen, L. Niu
Dental implants are widely used in the rehabilitation of patients with edentulous jaws caused by periodontitis. The success of implants is closely related to their framework material and patients' periodontal health. Polyetheretherketone (PEEK) is a kind of high polymer material that has broad prospects as the framework for full-arch dental prostheses, but long-term follow-up data are lacking. The present clinical report demonstrates the use of a PEEK framework for the construction of an implant-supported full-arch fixed dental prosthesis for a patient diagnosed with periodontitis. With the guidance of biological width, a provisional retained restoration was achieved to create the emergence profile, resulting in a 3D printed PEEK framework with good aesthetics and biological functions.
{"title":"Polyetheretherketone Framework for Implant-supported Full-arch Fixed Dental Prostheses in a Periodontitis Patient with a 6-year Follow-up: a Case Report.","authors":"Jing Wang, J. Gu, M. Meng, Chen Wang, Ji Hua Chen, L. Niu","doi":"10.3290/j.cjdr.b3086345","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086345","url":null,"abstract":"Dental implants are widely used in the rehabilitation of patients with edentulous jaws caused by periodontitis. The success of implants is closely related to their framework material and patients' periodontal health. Polyetheretherketone (PEEK) is a kind of high polymer material that has broad prospects as the framework for full-arch dental prostheses, but long-term follow-up data are lacking. The present clinical report demonstrates the use of a PEEK framework for the construction of an implant-supported full-arch fixed dental prosthesis for a patient diagnosed with periodontitis. With the guidance of biological width, a provisional retained restoration was achieved to create the emergence profile, resulting in a 3D printed PEEK framework with good aesthetics and biological functions.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"6 1","pages":"149-158"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82456669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE To assess the accuracy of transfer learning models for age estimation from panoramic photographs of permanent dentition of patients with an equal sex and age distribution and provide a new method of age estimation. METHODS The panoramic photographs of 3000 patients with an equal sex and age distribution were divided into three groups: a training set (n = 2400), validation set (n = 300) and test set (n = 300). The ResNet, EffiecientNet, VggNet and DenseNet transfer learning models were trained with the training set. The models were subsequently tested using the data in the test set. The mean absolute errors were calculated and the different features extracted by the deep learning models in different age groups were visualixed. RESULTS The mean absolute error (MAE) and root mean square error (RMSE) of the optimal transfer learning model EfficientNet-B5 in the test set were 2.83 and 4.59, respectively. The dentition, maxillary sinus, mandibular body and mandibular angle all played a role in age estimation. CONCLUSION Transfer learning models can extract different features in different age groups and can be used for age estimation in panoramic radiographs.
{"title":"Age Estimation using Panoramic Radiographs by Transfer Learning.","authors":"C. Mu, Gang Li","doi":"10.3290/j.cjdr.b3086341","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086341","url":null,"abstract":"OBJECTIVE\u0000To assess the accuracy of transfer learning models for age estimation from panoramic photographs of permanent dentition of patients with an equal sex and age distribution and provide a new method of age estimation.\u0000\u0000\u0000METHODS\u0000The panoramic photographs of 3000 patients with an equal sex and age distribution were divided into three groups: a training set (n = 2400), validation set (n = 300) and test set (n = 300). The ResNet, EffiecientNet, VggNet and DenseNet transfer learning models were trained with the training set. The models were subsequently tested using the data in the test set. The mean absolute errors were calculated and the different features extracted by the deep learning models in different age groups were visualixed.\u0000\u0000\u0000RESULTS\u0000The mean absolute error (MAE) and root mean square error (RMSE) of the optimal transfer learning model EfficientNet-B5 in the test set were 2.83 and 4.59, respectively. The dentition, maxillary sinus, mandibular body and mandibular angle all played a role in age estimation.\u0000\u0000\u0000CONCLUSION\u0000Transfer learning models can extract different features in different age groups and can be used for age estimation in panoramic radiographs.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"12 1","pages":"119-124"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81437865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés M Murillo-Pedrozo, E. Ronda-Pérez, E. Martínez-Herrera, A. Agudelo-Suárez
OBJECTIVE To gather the available scientific evidence about the oral health of migrants in south-south contexts. METHODS A scoping review methodology was applied through a comprehensive search in databases of scientific and grey literature: PubMed/Medline, Scopus, LILACS, EMBASE, Google Scholar and the International Centre for Migration, Health and Development. A descriptive analysis of the characteristics of the selected studies was conducted. RESULTS The search yielded 23 papers. Seventeen studies (17/23, 73.9%) were conducted on the Asian continent and 91.3% (21/23) were cross-sectional. Studies were focused on oral health problems such as dental caries and periodontal disease with diverse findings when comparing immigrants with natives. Some studies found poor oral health indexes in migrants. Migrants face barriers to dental health services. Other oral health variables addressed in the studies were oral health-related quality of life, beliefs, knowledge and practices in oral health. Determining factors related to oral health were evidenced, such as migration status, sociodemographic, cultural, psychological, living, economic and material conditions, social support, oral health practices and previous oral and general health status. Studies reported conceptual and methodological gaps and limitations that must be considered when interpreting the results. CONCLUSION According to the scientific evidence, immigrant populations in south-south migratory contexts show poor oral health indicators, and this translates into social vulnerability in this group. Further research is needed to increase the scientific body about the social and contextual determinants in oral health and understanding of the social construction of this phenomenon.
{"title":"A Scoping Review about Migrants' Oral Health in South-South Contexts.","authors":"Andrés M Murillo-Pedrozo, E. Ronda-Pérez, E. Martínez-Herrera, A. Agudelo-Suárez","doi":"10.3290/j.cjdr.b3116505","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3116505","url":null,"abstract":"OBJECTIVE\u0000To gather the available scientific evidence about the oral health of migrants in south-south contexts.\u0000\u0000\u0000METHODS\u0000A scoping review methodology was applied through a comprehensive search in databases of scientific and grey literature: PubMed/Medline, Scopus, LILACS, EMBASE, Google Scholar and the International Centre for Migration, Health and Development. A descriptive analysis of the characteristics of the selected studies was conducted.\u0000\u0000\u0000RESULTS\u0000The search yielded 23 papers. Seventeen studies (17/23, 73.9%) were conducted on the Asian continent and 91.3% (21/23) were cross-sectional. Studies were focused on oral health problems such as dental caries and periodontal disease with diverse findings when comparing immigrants with natives. Some studies found poor oral health indexes in migrants. Migrants face barriers to dental health services. Other oral health variables addressed in the studies were oral health-related quality of life, beliefs, knowledge and practices in oral health. Determining factors related to oral health were evidenced, such as migration status, sociodemographic, cultural, psychological, living, economic and material conditions, social support, oral health practices and previous oral and general health status. Studies reported conceptual and methodological gaps and limitations that must be considered when interpreting the results.\u0000\u0000\u0000CONCLUSION\u0000According to the scientific evidence, immigrant populations in south-south migratory contexts show poor oral health indicators, and this translates into social vulnerability in this group. Further research is needed to increase the scientific body about the social and contextual determinants in oral health and understanding of the social construction of this phenomenon.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"1 1","pages":"139-148"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88180715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chunzi Zhang, Shuo Du, W. H. Wang, Jian Liu, C. Yuan, Y. Yu, Shanshan Zhang, Y. Si
OBJECTIVE To investigate the relationship between chewing sugar-free gum (SFG) and dental caries status in China. METHODS A total of 860 teenagers (aged 12 to 15 years) and 490 adults (aged ≥ 18 years) were recruited using a multistage stratified cluster method from economically developed areas (Beijing, Guangdong) and less economically developed areas (Hubei, Xinjiang). Each participant completed a questionnaire including oral health-related knowledge of SFG and chewing habits of SFG and agreed to undertake a clinical assessment. Potential factors associated with chewing conditions were analysed through a chi-square statistical test. A negative binominal regression analysis was performed to quantify the relationship between dental caries and consumption of SFG. RESULTS The overall percentage of the survey population who consumed SFG was 43.4%, and SFG-related knowledge and awareness was only 19.4%. For decayed, missing and filled permanent teeth (DMFT), the mean value was 1.63 ± 2.41 and 2.29 ± 3.65 in the chewing group and non-chewing group, respectively. According to the negative binominal regression analysis, the caries status in the SFG chewing group was better than in the non-chewing group (adjusted prevalence rate ratio [PRR] 0.73; 95% confidence interval [CI] 0.62-0.87). CONCLUSION The chewing condition and oral health-related knowledge and awareness of SFG is low. Chewing SFG is related to a better dental caries status, so regular consumption of SFG should be recommended when promoting oral health.
{"title":"Relationship between Chewing Sugar-free Gum and Dental Caries Status in China.","authors":"Chunzi Zhang, Shuo Du, W. H. Wang, Jian Liu, C. Yuan, Y. Yu, Shanshan Zhang, Y. Si","doi":"10.3290/j.cjdr.b3086349","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086349","url":null,"abstract":"OBJECTIVE\u0000To investigate the relationship between chewing sugar-free gum (SFG) and dental caries status in China.\u0000\u0000\u0000METHODS\u0000A total of 860 teenagers (aged 12 to 15 years) and 490 adults (aged ≥ 18 years) were recruited using a multistage stratified cluster method from economically developed areas (Beijing, Guangdong) and less economically developed areas (Hubei, Xinjiang). Each participant completed a questionnaire including oral health-related knowledge of SFG and chewing habits of SFG and agreed to undertake a clinical assessment. Potential factors associated with chewing conditions were analysed through a chi-square statistical test. A negative binominal regression analysis was performed to quantify the relationship between dental caries and consumption of SFG.\u0000\u0000\u0000RESULTS\u0000The overall percentage of the survey population who consumed SFG was 43.4%, and SFG-related knowledge and awareness was only 19.4%. For decayed, missing and filled permanent teeth (DMFT), the mean value was 1.63 ± 2.41 and 2.29 ± 3.65 in the chewing group and non-chewing group, respectively. According to the negative binominal regression analysis, the caries status in the SFG chewing group was better than in the non-chewing group (adjusted prevalence rate ratio [PRR] 0.73; 95% confidence interval [CI] 0.62-0.87).\u0000\u0000\u0000CONCLUSION\u0000The chewing condition and oral health-related knowledge and awareness of SFG is low. Chewing SFG is related to a better dental caries status, so regular consumption of SFG should be recommended when promoting oral health.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"15 1","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76905561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitor Ferreira Balan, D. Botticelli, D. Peñarrocha-Oltra, K. Masuda, Eduardo Pires Godoy, S. Xavier
OBJECTIVE To compare the sequential healing of maxillary sinuses grafted with two different xenogeneic bone substitutes processed at either a low (300°C) or high (1200°C) temperature. METHODS A sinus augmentation procedure was performed bilaterally in 20 rabbits and two different xenogeneic bone grafts were randomly used to fill the elevated spaces. Healing was studied after 2 and 10 weeks, in 10 rabbits during each period. RESULTS After 2 weeks of healing, very small amounts of new bone were observed in both groups, and were mainly confined to close to the sinus bone walls and osteotomy edges. After 10 weeks of healing, new bone was found in all regions, with higher percentages in those close to the bone walls and to the osteotomy. In this period of healing, the proportion of new bone in the 300°C group was 20.0% ± 4.3%, and in the 1200°C group it was 17.2% ± 4.3% (P = 0.162). In the 1200°C group, translucent, dark fog-like shadows in regions of the grafts were hiding portions of new bone (interpenetrating bone network). CONCLUSION Both biomaterials provided conditions that allowed bone growth within the elevated space, confirming that both biomaterials are suitable to be used as a graft for sinus floor augmentation.
{"title":"Maxillary Sinus Floor Augmentation with Two Different Inorganic Bovine Bone Grafts: an Experimental Study in Rabbits.","authors":"Vitor Ferreira Balan, D. Botticelli, D. Peñarrocha-Oltra, K. Masuda, Eduardo Pires Godoy, S. Xavier","doi":"10.3290/j.cjdr.b3086337","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086337","url":null,"abstract":"OBJECTIVE\u0000To compare the sequential healing of maxillary sinuses grafted with two different xenogeneic bone substitutes processed at either a low (300°C) or high (1200°C) temperature.\u0000\u0000\u0000METHODS\u0000A sinus augmentation procedure was performed bilaterally in 20 rabbits and two different xenogeneic bone grafts were randomly used to fill the elevated spaces. Healing was studied after 2 and 10 weeks, in 10 rabbits during each period.\u0000\u0000\u0000RESULTS\u0000After 2 weeks of healing, very small amounts of new bone were observed in both groups, and were mainly confined to close to the sinus bone walls and osteotomy edges. After 10 weeks of healing, new bone was found in all regions, with higher percentages in those close to the bone walls and to the osteotomy. In this period of healing, the proportion of new bone in the 300°C group was 20.0% ± 4.3%, and in the 1200°C group it was 17.2% ± 4.3% (P = 0.162). In the 1200°C group, translucent, dark fog-like shadows in regions of the grafts were hiding portions of new bone (interpenetrating bone network).\u0000\u0000\u0000CONCLUSION\u0000Both biomaterials provided conditions that allowed bone growth within the elevated space, confirming that both biomaterials are suitable to be used as a graft for sinus floor augmentation.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"18 1","pages":"93-105"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73390736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Song Jiang, J. Nie, Yu Chen, Xiao Yan Wang, Fengwang Chen
OBJECTIVE To investigate the composition and abundance of candidate phyla radiation (CPR) in the oral cavity in caries patients and a healthy population. METHODS The raw macrogenomic sequencing data for a total of 88 subjects were downloaded from the National Centre for Biotechnology Sequence Read Archive (NCBI SRA) public database according to the public data usage specifications. Trimmomatic (Department for Metabolic Networks, Potsdam, Germany) and Bowtie 2 (University of Maryland, College Park, MD, USA) were used to quality control and dehost the host sequences. Species annotation was made using Kraken2 (Johns Hopkins University, Baltimore, MD, USA) and Bracken (Johns Hopkins University) based on the reference database. According to the results of the species annotation, the species-significant differences and species correlation of caries and healthy oral microbiota in species composition and microbiota diversity were analysed to study the distribution and abundance differences of CPR in the oral environment. RESULTS Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria and Fusobacteria were the main components. The relative abundance of TM7 (Candidatus Saccharibacteria) and GN02 (Candidatus Gracilibacteria) of CPR is second only to the aforementioned five bacteria, indicating that CPR is an important part of the oral microbiota. TM7 and GN02 were common to both the caries patients and healthy patients and were detected in all samples, suggesting that CPR is the 'core microbiome'. There was a correlation between CPR and a variety of oral microbiota, among which the positive correlation with Capnocytophaga was the strongest, suggesting that Capnocytophaga might be the potential host bacteria of CPR. CONCLUSION CPR is an indispensable part of the oral microbiota. It is the 'core microflora' of the oral cavity and may play an important role in the stability and function of the oral microecological environment. Capnocytophaga may be the potential host bacteria of CPR.
{"title":"Structure and Composition of Candidate Phyla Radiation in Supragingival Plaque of Caries Patients.","authors":"Song Jiang, J. Nie, Yu Chen, Xiao Yan Wang, Fengwang Chen","doi":"10.3290/j.cjdr.b3086339","DOIUrl":"https://doi.org/10.3290/j.cjdr.b3086339","url":null,"abstract":"OBJECTIVE\u0000To investigate the composition and abundance of candidate phyla radiation (CPR) in the oral cavity in caries patients and a healthy population.\u0000\u0000\u0000METHODS\u0000The raw macrogenomic sequencing data for a total of 88 subjects were downloaded from the National Centre for Biotechnology Sequence Read Archive (NCBI SRA) public database according to the public data usage specifications. Trimmomatic (Department for Metabolic Networks, Potsdam, Germany) and Bowtie 2 (University of Maryland, College Park, MD, USA) were used to quality control and dehost the host sequences. Species annotation was made using Kraken2 (Johns Hopkins University, Baltimore, MD, USA) and Bracken (Johns Hopkins University) based on the reference database. According to the results of the species annotation, the species-significant differences and species correlation of caries and healthy oral microbiota in species composition and microbiota diversity were analysed to study the distribution and abundance differences of CPR in the oral environment.\u0000\u0000\u0000RESULTS\u0000Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria and Fusobacteria were the main components. The relative abundance of TM7 (Candidatus Saccharibacteria) and GN02 (Candidatus Gracilibacteria) of CPR is second only to the aforementioned five bacteria, indicating that CPR is an important part of the oral microbiota. TM7 and GN02 were common to both the caries patients and healthy patients and were detected in all samples, suggesting that CPR is the 'core microbiome'. There was a correlation between CPR and a variety of oral microbiota, among which the positive correlation with Capnocytophaga was the strongest, suggesting that Capnocytophaga might be the potential host bacteria of CPR.\u0000\u0000\u0000CONCLUSION\u0000CPR is an indispensable part of the oral microbiota. It is the 'core microflora' of the oral cavity and may play an important role in the stability and function of the oral microecological environment. Capnocytophaga may be the potential host bacteria of CPR.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"36 1","pages":"107-118"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77829137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE To conduct a systemic review for guidance regarding the application of templates in mandibular reconstruction with vascularised iliac flaps. METHODS By searching PubMed, EMBASE and the Cochrane Library and collecting relevant literature, information about the types and accuracy of templates was extracted. Data relating to surgical time were also included for further analysis. RESULTS Eight studies were included. The data analysis showed that the accuracy of operations with templates was higher than that of conventional surgery. The mean deviation was between 0.70 and 3.72 mm. The operational time was shortened to 314.4 minutes and the graft ischemic time was reduced to 15.6 to 26.8 minutes. Application of functional or specifically designed templates can improve the accuracy and shorten surgical time. CONCLUSION Templates can increase the accuracy and efficiency of mandibular reconstruction with vascularised iliac flaps, which will benefit patients' prognosis and subsequent functional restoration. Further studies should be conducted into application of templates to improve the accuracy of reconstructions.
{"title":"Accuracy of Mandibular Reconstruction with a Vascularised Iliac Flap Using 3D Templates: a Systematic Review.","authors":"Tingwei Lu, Wanbo Chen, T. Ji","doi":"10.3290/j.cjdr.b2752689","DOIUrl":"https://doi.org/10.3290/j.cjdr.b2752689","url":null,"abstract":"OBJECTIVE\u0000To conduct a systemic review for guidance regarding the application of templates in mandibular reconstruction with vascularised iliac flaps.\u0000\u0000\u0000METHODS\u0000By searching PubMed, EMBASE and the Cochrane Library and collecting relevant literature, information about the types and accuracy of templates was extracted. Data relating to surgical time were also included for further analysis.\u0000\u0000\u0000RESULTS\u0000Eight studies were included. The data analysis showed that the accuracy of operations with templates was higher than that of conventional surgery. The mean deviation was between 0.70 and 3.72 mm. The operational time was shortened to 314.4 minutes and the graft ischemic time was reduced to 15.6 to 26.8 minutes. Application of functional or specifically designed templates can improve the accuracy and shorten surgical time.\u0000\u0000\u0000CONCLUSION\u0000Templates can increase the accuracy and efficiency of mandibular reconstruction with vascularised iliac flaps, which will benefit patients' prognosis and subsequent functional restoration. Further studies should be conducted into application of templates to improve the accuracy of reconstructions.","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"14 1","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75519482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial.","authors":"Guang-Yan Yu","doi":"10.3290/j.cjdr.b2812805","DOIUrl":"https://doi.org/10.3290/j.cjdr.b2812805","url":null,"abstract":"","PeriodicalId":22405,"journal":{"name":"The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association","volume":"3 1","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85984323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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