Pub Date : 2021-12-10DOI: 10.21048/ijnd.2021.58.4.28560
Nitthya Kochadai, R. Mahendran, Y. Bhosale, Hema Vincent, Sinija Vadakkepulppara Ramachandran Nair
Tender coconut and Palmyra are known for their micro minerals and nutrients that are essential for human health and consumed mostly in tropical countries. The growing demand for low-alcohol beverages and natural preservation techniques for these raw materials necessitated the need for the present study, which aims to assess the suitability of these raw materials for the production of low-alcohol wine. Different blend ratios of tender coconut and palmyra juice ranging from 80:20 to 20:80 were subjected to fermentation. The wine was filtered and analysed for physicochemical, phytochemical properties and mineral profile. Initially, all the samples were adjusted to 20°Brix which decreased to a range of 6.25 ± 0.28 to 13.23 ± 0.48°Brix and alcohol content between 4.1 ± 0.16% (A7) and 8.1 ± 0.41% (A1) with phenols and antioxidants (421.63 ± 11.15 to 650.72 ± 10.15 mgGAE/100 mL and 57.38 ± 0.002% to 85.95 ± 0.0004%, respectively). Principle component analysis revealed A5 (60:40 palmyra: tender coconut) as the most acceptable blend with high micronutrients like vitamin C (49.92 mg/100 mL), potassium (3338.27 mg/L), sodium (218.87 mg/L) and magnesium (132.8 mg/L). The study throws light to the utilization of highly perishable tender coconut and palmyra endosperm to make a shelf-stable refreshing low-alcoholic wine with high antioxidants and mineral content.
{"title":"Development of Low Alcoholic Wine Using Tender Coconut and Tender Palmyra as a Novel Source and its Quality Evaluation","authors":"Nitthya Kochadai, R. Mahendran, Y. Bhosale, Hema Vincent, Sinija Vadakkepulppara Ramachandran Nair","doi":"10.21048/ijnd.2021.58.4.28560","DOIUrl":"https://doi.org/10.21048/ijnd.2021.58.4.28560","url":null,"abstract":"Tender coconut and Palmyra are known for their micro minerals and nutrients that are essential for human health and consumed mostly in tropical countries. The growing demand for low-alcohol beverages and natural preservation techniques for these raw materials necessitated the need for the present study, which aims to assess the suitability of these raw materials for the production of low-alcohol wine. Different blend ratios of tender coconut and palmyra juice ranging from 80:20 to 20:80 were subjected to fermentation. The wine was filtered and analysed for physicochemical, phytochemical properties and mineral profile. Initially, all the samples were adjusted to 20°Brix which decreased to a range of 6.25 ± 0.28 to 13.23 ± 0.48°Brix and alcohol content between 4.1 ± 0.16% (A7) and 8.1 ± 0.41% (A1) with phenols and antioxidants (421.63 ± 11.15 to 650.72 ± 10.15 mgGAE/100 mL and 57.38 ± 0.002% to 85.95 ± 0.0004%, respectively). Principle component analysis revealed A5 (60:40 palmyra: tender coconut) as the most acceptable blend with high micronutrients like vitamin C (49.92 mg/100 mL), potassium (3338.27 mg/L), sodium (218.87 mg/L) and magnesium (132.8 mg/L). The study throws light to the utilization of highly perishable tender coconut and palmyra endosperm to make a shelf-stable refreshing low-alcoholic wine with high antioxidants and mineral content.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90316549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-10DOI: 10.21048/ijnd.2021.58.4.27990
K. K. Godisela, M. Puppala, T. Shalini
COVID-19 is a worldwide emergency of public health that leads to lockouts, changes in the dietary pattern and life-style of the population. To assess the impact of COVID-19 mediated lockdown on nutrition, health and lifestyle patterns among teenagers aged ?18 years. A standardized questionnaire was used to collect data on demographics (age, gender and place of residence), food system dimensions, dietary intake, physical activity, stress and anxiety, body image attitudes, lifestyle behaviours such as smoking, alcohol consumption, screentime and ease of access to health services. Most of the participants (n=537) were women (53.9%) aged 16 to 24. The lockdown has led to an increase in food prices (81.4%) and a decrease in the rate of physical activity (67.4%). Additionally, there is an increased intake of fruits (68.7%), meat (60%), eggs (75%) and leafy vegetables (49.9%). Around 44.5% of the people reported stress for some days. The majority of the students have increased their weight by 53.8%, weight loss by 10.6% and no change in weight by 30.2%. Approximately half (52.3%) reported challenging access to pharmaceuticals and 66.7% had medical emergency services. An increase in food price, decreased dietary diversification, unhealthy eating patterns, lack of physical activity and perceived weight gain were demonstrated during the COVID-19 induced lockdown period. Further research is needed from various socioeconomic backgrounds to obtain more definitive results which may improve the quality of life of the people.
{"title":"The Impact of the COVID-19-Induced Lockdown on SRR College Undergraduate Student’s Nutrition, Health and Lifestyle Patterns","authors":"K. K. Godisela, M. Puppala, T. Shalini","doi":"10.21048/ijnd.2021.58.4.27990","DOIUrl":"https://doi.org/10.21048/ijnd.2021.58.4.27990","url":null,"abstract":"COVID-19 is a worldwide emergency of public health that leads to lockouts, changes in the dietary pattern and life-style of the population. To assess the impact of COVID-19 mediated lockdown on nutrition, health and lifestyle patterns among teenagers aged ?18 years. A standardized questionnaire was used to collect data on demographics (age, gender and place of residence), food system dimensions, dietary intake, physical activity, stress and anxiety, body image attitudes, lifestyle behaviours such as smoking, alcohol consumption, screentime and ease of access to health services. Most of the participants (n=537) were women (53.9%) aged 16 to 24. The lockdown has led to an increase in food prices (81.4%) and a decrease in the rate of physical activity (67.4%). Additionally, there is an increased intake of fruits (68.7%), meat (60%), eggs (75%) and leafy vegetables (49.9%). Around 44.5% of the people reported stress for some days. The majority of the students have increased their weight by 53.8%, weight loss by 10.6% and no change in weight by 30.2%. Approximately half (52.3%) reported challenging access to pharmaceuticals and 66.7% had medical emergency services. An increase in food price, decreased dietary diversification, unhealthy eating patterns, lack of physical activity and perceived weight gain were demonstrated during the COVID-19 induced lockdown period. Further research is needed from various socioeconomic backgrounds to obtain more definitive results which may improve the quality of life of the people.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89542205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/ijnd.2021.58.3.27707
R. Durga Priyadarshini, D. Annette Beatrice
With increasing prevalence of metabolic syndrome among tribal population in India, the present study aimed to assess the incidence of metabolic syndrome and examine the differences in the dietary intake of tribal women residing in Kolagur, a hamlet in Yercaud block, Salem district, Tamil Nadu, India. One hundred women between the age of 18-60 years were randomly selected and information pertaining to their socio-demographic profile were elicited using a structured questionnaire. Anthropometric, biochemical, clinical and dietary parameters were assessed using appropriate validated tools. Nutrient intake was computed using Diet Cal software and the statistical analysis was done using ‘R' statistical software. Of the 100 tribal women, 26% were diagnosed with metabolic syndrome majorly prevalent among the age group of 40-60 years (53.8%). The most common feature of metabolic syndrome was low HDL cholesterol (88.5%). There were no significant differences in the socio-demographic profile of tribal women from both groups. Women with metabolic syndrome were found to have significant difference in all the anthropometric parameters with higher mean BMI (p<0.000), mean waist-to-hip ratio (p<0.000) and mean body fat (p<0.000) than those without metabolic syndrome. The mean fasting plasma glucose (p<0.000), mean triglycerides (p<0.000), mean total cholesterol: HDL cholesterol ratio (p=0.0007), mean systolic blood pressure level (p<0.000) and mean diastolic blood pressure level (p<0.000) were significantly higher and mean HDL - cholesterol was significantly lower (p=0.011) among those with metabolic syndrome. With respect to dietary intake, the mean intake of energy (p=0.012) and carbohydrates (p=0.034) of women with metabolic syndrome were significantly lesser than those without metabolic syndrome. These results imply the need for a cohort with larger sample size to gain more insight into the plausible diet-disease relationship. Long term interventions aimed to treat women with metabolic syndrome is crucial to prevent the onset of non-communicable diseases.
{"title":"Dietary Intake and Metabolic Syndrome in Kolagur Tribal Women, Yercaud","authors":"R. Durga Priyadarshini, D. Annette Beatrice","doi":"10.21048/ijnd.2021.58.3.27707","DOIUrl":"https://doi.org/10.21048/ijnd.2021.58.3.27707","url":null,"abstract":"With increasing prevalence of metabolic syndrome among tribal population in India, the present study aimed to assess the incidence of metabolic syndrome and examine the differences in the dietary intake of tribal women residing in Kolagur, a hamlet in Yercaud block, Salem district, Tamil Nadu, India. One hundred women between the age of 18-60 years were randomly selected and information pertaining to their socio-demographic profile were elicited using a structured questionnaire. Anthropometric, biochemical, clinical and dietary parameters were assessed using appropriate validated tools. Nutrient intake was computed using Diet Cal software and the statistical analysis was done using ‘R' statistical software. Of the 100 tribal women, 26% were diagnosed with metabolic syndrome majorly prevalent among the age group of 40-60 years (53.8%). The most common feature of metabolic syndrome was low HDL cholesterol (88.5%). There were no significant differences in the socio-demographic profile of tribal women from both groups. Women with metabolic syndrome were found to have significant difference in all the anthropometric parameters with higher mean BMI (p<0.000), mean waist-to-hip ratio (p<0.000) and mean body fat (p<0.000) than those without metabolic syndrome. The mean fasting plasma glucose (p<0.000), mean triglycerides (p<0.000), mean total cholesterol: HDL cholesterol ratio (p=0.0007), mean systolic blood pressure level (p<0.000) and mean diastolic blood pressure level (p<0.000) were significantly higher and mean HDL - cholesterol was significantly lower (p=0.011) among those with metabolic syndrome. With respect to dietary intake, the mean intake of energy (p=0.012) and carbohydrates (p=0.034) of women with metabolic syndrome were significantly lesser than those without metabolic syndrome. These results imply the need for a cohort with larger sample size to gain more insight into the plausible diet-disease relationship. Long term interventions aimed to treat women with metabolic syndrome is crucial to prevent the onset of non-communicable diseases.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80652252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27283
Aparna Kumari, G. Gautam, A. Chauhan, Meenakshi Singh, Arshya Singh
Onion is one of the most important vegetables used as a food ingredient and spice due to its flavor, aroma and pungency. Chemical composition of onion revealed that it contains vitamins, carbohydrates, proteins, minerals, dietary fiber, some cysteine derivatives and phenolic compounds. It has many medicinal benefits like wound healing, growth-inhibition of microbial and tumor cells, reduction of cancer risk, protection against cardiovascular diseases and diabetes and anti-inflammatory properties. However, post harvest loss during storage remains a major challenge for food researchers. To prevent price hikes and increase the shelf life of onion, preservation is a crucial step. The present study was conducted to evaluate the effect of the sun, tray, vacuum and freeze-drying treatment on the nutritional, functional and sensory acceptability of onion powders. The result indicates that the nutritional, color, texture, rheological and rehydration ratio of freezedried onion powder were better than other drying processes. Volatile compounds retain in lyophilized onion powder. However, they may be readily lost during other drying processes. Based on the micro-structure analysis of onion powder, the freeze-dried powder was found intact and porous cell. There was no leak of solute concentration. It can be concluded that among all drying methods, freeze-drying is considered the best method to preserve onions in various form like powder, flakes and was well accepted by the sensory panel.
{"title":"Effect of Different Drying Methods on Nutritional and Functional Properties of Onion Powder","authors":"Aparna Kumari, G. Gautam, A. Chauhan, Meenakshi Singh, Arshya Singh","doi":"10.21048/IJND.2021.58.3.27283","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27283","url":null,"abstract":"Onion is one of the most important vegetables used as a food ingredient and spice due to its flavor, aroma and pungency. Chemical composition of onion revealed that it contains vitamins, carbohydrates, proteins, minerals, dietary fiber, some cysteine derivatives and phenolic compounds. It has many medicinal benefits like wound healing, growth-inhibition of microbial and tumor cells, reduction of cancer risk, protection against cardiovascular diseases and diabetes and anti-inflammatory properties. However, post harvest loss during storage remains a major challenge for food researchers. To prevent price hikes and increase the shelf life of onion, preservation is a crucial step. The present study was conducted to evaluate the effect of the sun, tray, vacuum and freeze-drying treatment on the nutritional, functional and sensory acceptability of onion powders. The result indicates that the nutritional, color, texture, rheological and rehydration ratio of freezedried onion powder were better than other drying processes. Volatile compounds retain in lyophilized onion powder. However, they may be readily lost during other drying processes. Based on the micro-structure analysis of onion powder, the freeze-dried powder was found intact and porous cell. There was no leak of solute concentration. It can be concluded that among all drying methods, freeze-drying is considered the best method to preserve onions in various form like powder, flakes and was well accepted by the sensory panel. ","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86471792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27554
Srishti Sinha, R. Kuriyan
Indian adults tend to inappropriately accumulate body fat even at low Body Mass Index (BMI). Usually, fat that is stored in the fed state is mobilized for energy during nocturnal fasting, thus achieving daily fat balance. This is called metabolic flexibility, which may be lost in some individuals leading to body fat accumulation. Measuring fat balance requires 24h measurement of fat oxidation, but nocturnal fat oxidation could be a reasonable surrogate. The variability of nocturnal fat oxidation is also unknown. A retrospective analysis on 24h fat oxidation in adult men (n=18) was carried out to test the former hypothesis, while the variability of nocturnal fat oxidation was measured prospectively in 5 adult men, who were fed the same diet for 2 days prior to the measurement. Whole-body indirect calorimetry was used for measuring Respiratory Quotient (RQ), energy expenditure and fat oxidation. In 24h analyses, nocturnal (0.44 ± 0.21 g/kg) was significantly higher than diurnal fat oxidation (0.24 ± 0.21 g/kg) and was 64.5% of the total 24h value. Nocturnal fat oxidation was positively correlated with 24h fat oxidation (r = 0.937; p<0.01) and inversely correlated with 24h fat balance (r = -0.850; p<0.01). Metabolic flexibility, measured as the Fed: Fasted RQ ratio, was negatively correlated with BMI (r = -0.226; p=0.366). The intra- and inter-individual variability of 12h nocturnal fat oxidation was low, at 4.7% and 7.2%, respectively. Nocturnal fat oxidation has a low variability when prior diets over 2 days are constant and the Fed: Fasted RQ ratio is an index of metabolic flexibility, which relates to BMI in young adults.
{"title":"Nocturnal Fat Oxidation and Metabolic Flexibility of Young Male Indian Adults Using Indirect Calorimetry","authors":"Srishti Sinha, R. Kuriyan","doi":"10.21048/IJND.2021.58.3.27554","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27554","url":null,"abstract":"Indian adults tend to inappropriately accumulate body fat even at low Body Mass Index (BMI). Usually, fat that is stored in the fed state is mobilized for energy during nocturnal fasting, thus achieving daily fat balance. This is called metabolic flexibility, which may be lost in some individuals leading to body fat accumulation. Measuring fat balance requires 24h measurement of fat oxidation, but nocturnal fat oxidation could be a reasonable surrogate. The variability of nocturnal fat oxidation is also unknown. A retrospective analysis on 24h fat oxidation in adult men (n=18) was carried out to test the former hypothesis, while the variability of nocturnal fat oxidation was measured prospectively in 5 adult men, who were fed the same diet for 2 days prior to the measurement. Whole-body indirect calorimetry was used for measuring Respiratory Quotient (RQ), energy expenditure and fat oxidation. In 24h analyses, nocturnal (0.44 ± 0.21 g/kg) was significantly higher than diurnal fat oxidation (0.24 ± 0.21 g/kg) and was 64.5% of the total 24h value. Nocturnal fat oxidation was positively correlated with 24h fat oxidation (r = 0.937; p<0.01) and inversely correlated with 24h fat balance (r = -0.850; p<0.01). Metabolic flexibility, measured as the Fed: Fasted RQ ratio, was negatively correlated with BMI (r = -0.226; p=0.366). The intra- and inter-individual variability of 12h nocturnal fat oxidation was low, at 4.7% and 7.2%, respectively. Nocturnal fat oxidation has a low variability when prior diets over 2 days are constant and the Fed: Fasted RQ ratio is an index of metabolic flexibility, which relates to BMI in young adults.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88880022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27233
D. Dhawan, Shailja Sharma
SARS-CoV-2 infection has become a widely spread disease around the world causing rapid hospitalization and death, especially in people with metabolic syndrome. There is very limited literature that goes to present the clinical implications and management of metabolic syndrome in this pandemic. Hence an attempt has been made towards meeting this end. A literature review has been done extracting articles from scopus database following PRISMA guidelines. The manuscripts were studied to identify articles that report metabolic syndrome and its components in COVID-19 infection. A total of 25 manuscripts were included in this systematic review. These studies report systematic inflammation and organ damage in metabolic syndrome that has up regulated SARS-CoV-2 infection. Various treatment strategies have also been suggested and hypothesized. The results of this analysis indicate that patients suffering from metabolic syndrome are vulnerable to COVID-19 owing a sequence of complications.
{"title":"Systematic Review: Vulnerability of Metabolic Syndrome in COVID-19","authors":"D. Dhawan, Shailja Sharma","doi":"10.21048/IJND.2021.58.3.27233","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27233","url":null,"abstract":"SARS-CoV-2 infection has become a widely spread disease around the world causing rapid hospitalization and death, especially in people with metabolic syndrome. There is very limited literature that goes to present the clinical implications and management of metabolic syndrome in this pandemic. Hence an attempt has been made towards meeting this end. A literature review has been done extracting articles from scopus database following PRISMA guidelines. The manuscripts were studied to identify articles that report metabolic syndrome and its components in COVID-19 infection. A total of 25 manuscripts were included in this systematic review. These studies report systematic inflammation and organ damage in metabolic syndrome that has up regulated SARS-CoV-2 infection. Various treatment strategies have also been suggested and hypothesized. The results of this analysis indicate that patients suffering from metabolic syndrome are vulnerable to COVID-19 owing a sequence of complications.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76086323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27285
Mehrukh Zehravi, Mudasir Maqbool, I. Ara
One pathway for more actively monitoring Adverse Drug Reactions (ADRs) and, as a result, improving patient care safety is a structured Adverse Drug Reaction Surveillance network. Multiple methods for testing and recording the efficacy of drugs in clinical use are important for avoiding or reducing patient injury and strengthening public health. This entails establishing a well-structured Pharmacovigilance programme in clinical practise. Once a prescription has been published into the "true world," pharmacovigilance is an important method of monitoring medication-related issues. Pharmacovigilance and other drug-related problems should be familiar to those whose life is impacted by prescription procedures in some way. In modern times, pharmacovigilance has gained prominence as a technology critical to sound clinical practise and public health science. Since ADRs have such a detrimental influence on patients' wellbeing and inflict too much financial strain, it's critical to carefully monitor each medication for any potential adverse effects in animal models (preclinical studies) and clinical trials until releasing it. Pharmacovigilance aims to serve a significant part in combating the dangers faced by an ever-growing number of drugs, each of which is vulnerable to unpredictably negative side effects. When adverse effects and toxicity occur, they must be recorded, analysed and the importance of the results correctly communicated to those who may understand the evidence. By ensuring that prescription drugs of high consistency, purity and effectiveness are used rationally, the risk of injury will be minimised. In this study it will briefly explore adverse drug reaction safety control and pharmacovigilance in India.
{"title":"An Overview about Safety Surveillance of Adverse Drug Reactions and Pharmacovigilance in India","authors":"Mehrukh Zehravi, Mudasir Maqbool, I. Ara","doi":"10.21048/IJND.2021.58.3.27285","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27285","url":null,"abstract":"One pathway for more actively monitoring Adverse Drug Reactions (ADRs) and, as a result, improving patient care safety is a structured Adverse Drug Reaction Surveillance network. Multiple methods for testing and recording the efficacy of drugs in clinical use are important for avoiding or reducing patient injury and strengthening public health. This entails establishing a well-structured Pharmacovigilance programme in clinical practise. Once a prescription has been published into the \"true world,\" pharmacovigilance is an important method of monitoring medication-related issues. Pharmacovigilance and other drug-related problems should be familiar to those whose life is impacted by prescription procedures in some way. In modern times, pharmacovigilance has gained prominence as a technology critical to sound clinical practise and public health science. Since ADRs have such a detrimental influence on patients' wellbeing and inflict too much financial strain, it's critical to carefully monitor each medication for any potential adverse effects in animal models (preclinical studies) and clinical trials until releasing it. Pharmacovigilance aims to serve a significant part in combating the dangers faced by an ever-growing number of drugs, each of which is vulnerable to unpredictably negative side effects. When adverse effects and toxicity occur, they must be recorded, analysed and the importance of the results correctly communicated to those who may understand the evidence. By ensuring that prescription drugs of high consistency, purity and effectiveness are used rationally, the risk of injury will be minimised. In this study it will briefly explore adverse drug reaction safety control and pharmacovigilance in India.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85861633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27164
Vivekananthan Suseela, R. Nirmaladevi
Medicinal plants have been used in folkloric medicine to treat various ailments. The compound investigations of medicinal plants have largely been driven to discover new drugs to treat human diseases. The study was designed to estimate the amount of phytochemical constituents and also to explore the presence of bioactive compounds in ethanolic extract of Tabebuia roseo-alba using Gas Chromatography-Mass Spectrometry (GC-MS). Quantitative phytochemical analysis was carried out by standard procedures. GC-MS analysis of the plant extracts was performed by using GC SHIMADZU QP2010 system and Gas Chromatograph interfaced to a Mass Spectrometer (GC-MS) equipped with RXi -1ms fused silica capillary column. The total phenol content was found to be 112.67+0.03 in ethanolic extract of Tabebuia roseo-alba leaves. The GC-MS analysis revealed the presence of eight major peaks from which various bioactive compounds were ascertained. In conclusion, ethanolic extract of Tabebuia roseo-alba possess many bioactive constituents which may be accountable for its various pharmacological activities.
{"title":"Quantitative Phytochemical Screening and GC-MS Analysis of the Ethanolic Extract of Tabebuia roseo-alba (Ridl) Sand","authors":"Vivekananthan Suseela, R. Nirmaladevi","doi":"10.21048/IJND.2021.58.3.27164","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27164","url":null,"abstract":"Medicinal plants have been used in folkloric medicine to treat various ailments. The compound investigations of medicinal plants have largely been driven to discover new drugs to treat human diseases. The study was designed to estimate the amount of phytochemical constituents and also to explore the presence of bioactive compounds in ethanolic extract of Tabebuia roseo-alba using Gas Chromatography-Mass Spectrometry (GC-MS). Quantitative phytochemical analysis was carried out by standard procedures. GC-MS analysis of the plant extracts was performed by using GC SHIMADZU QP2010 system and Gas Chromatograph interfaced to a Mass Spectrometer (GC-MS) equipped with RXi -1ms fused silica capillary column. The total phenol content was found to be 112.67+0.03 in ethanolic extract of Tabebuia roseo-alba leaves. The GC-MS analysis revealed the presence of eight major peaks from which various bioactive compounds were ascertained. In conclusion, ethanolic extract of Tabebuia roseo-alba possess many bioactive constituents which may be accountable for its various pharmacological activities.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85675290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.27099
Barkha Sachdeva, S. Puri, R. Arora
Beyond genetics, there are several environmental factors which are responsible for the surging rates of obesity. Food advertisements being a part of multiple levels of food environment influence eating habits and contributes to obesity and other noncommunicable diseases. This research was a triphasic study conducted to evaluate the content of food advertisements appearing on most popular TV channels watched by children and their mothers, living in Delhi. In the first phase, TV viewing pattern of 30 children (8-12 years) and their mothers was determined, followed by the second phase which involved observation of food advertisements on most watched TV channels. In last phase, content analysis of food advertisements and corresponding food labels was carried out vis-a-vis advertising appeals (emotional and rational) and health/nutrition claims in accordance with Food Safety and Standards (Advertising and Claims) Regulations, 2018 and Advertising Council of India (ASCI) guidelines. Television viewing was identified as a regular habit among children and their mothers with the preferred time slot of 8 p.m. to 11 p.m. The most watched advertised food category among children was chocolate / candies / lollipops (80%) and among mothers were grocery products (96.6%). Compared to mainstream, proportion of food commercials was almost double on kids' channels however; most advertised food category (chocolate / candies / lollipops) was found to be common on both channels. Use of advertising appeals along with health / nutrition claims (56%) was prevalent in food advertisements. No gross violation of claims was found; however, few conditional and health claims were depicted in a manner to mislead the consumers.
{"title":"Content Analysis of Food Related Television Advertisements Aimed at Children and Women: A Pilot Study in Delhi","authors":"Barkha Sachdeva, S. Puri, R. Arora","doi":"10.21048/IJND.2021.58.3.27099","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.27099","url":null,"abstract":"Beyond genetics, there are several environmental factors which are responsible for the surging rates of obesity. Food advertisements being a part of multiple levels of food environment influence eating habits and contributes to obesity and other noncommunicable diseases. This research was a triphasic study conducted to evaluate the content of food advertisements appearing on most popular TV channels watched by children and their mothers, living in Delhi. In the first phase, TV viewing pattern of 30 children (8-12 years) and their mothers was determined, followed by the second phase which involved observation of food advertisements on most watched TV channels. In last phase, content analysis of food advertisements and corresponding food labels was carried out vis-a-vis advertising appeals (emotional and rational) and health/nutrition claims in accordance with Food Safety and Standards (Advertising and Claims) Regulations, 2018 and Advertising Council of India (ASCI) guidelines. Television viewing was identified as a regular habit among children and their mothers with the preferred time slot of 8 p.m. to 11 p.m. The most watched advertised food category among children was chocolate / candies / lollipops (80%) and among mothers were grocery products (96.6%). Compared to mainstream, proportion of food commercials was almost double on kids' channels however; most advertised food category (chocolate / candies / lollipops) was found to be common on both channels. Use of advertising appeals along with health / nutrition claims (56%) was prevalent in food advertisements. No gross violation of claims was found; however, few conditional and health claims were depicted in a manner to mislead the consumers.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89724602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-07DOI: 10.21048/IJND.2021.58.3.28401
Jyothi S. Krishnan, A. Devi
Poly cystic ovarian syndrome (PCOS) is a heterogeneous disorder common among reproductive age women. The study was focused to compare the clinical findings and nutritional status of women with PCOS in 18-29 and 30-45 year age groups. Overall, 120 PCOS subjects in the age group of 18-45 years were selected for the study. Rotterdam criteria was used for identification of the subjects for the study. Socio economic status of the subject revealed that majority of the subjects (49 %) belonged to upper lower class IV. There was a significant mean difference in BMI (p=0.007), Oligo an ovulation (p=0.02) between the two groups. The mean Scores of hirsutism and physical activity was significantly higher in the 18-29 age group (p<0.05). Nutrient intake was assessed by three day food record and food frequency questionnaire (FFQ) and calculated using Diet Cal software. The mean intake of calorie, carbohydrate and fat was remarkably higher in both age groups whereas the intake of micronutrients such as calcium, zinc, iron and retinol was lower compared to EAR. Vitamin D intake was lower than the EAR in all the selected subjects. The comparison of nutritional status of the two age groups disclosed that there was a significantly higher mean intake of calorie (p=0.045), fibre (p=0.006), iron (p=0.022), magnesium (p=0.017), chromium (p=0.016) and potassium (p=0.041) in the 30-45 year age group. Food consumption pattern affirmed that there was a remarkable difference in the intake of processed foods, soft drinks, sweets, fish, leafy vegetables, pickle between the two age groups.
{"title":"Comparison of Clinical Findings and Nutritional Status in Women with Poly Cystic Ovarian Syndrome in 18-29 and 30-45 Year Age Groups","authors":"Jyothi S. Krishnan, A. Devi","doi":"10.21048/IJND.2021.58.3.28401","DOIUrl":"https://doi.org/10.21048/IJND.2021.58.3.28401","url":null,"abstract":"Poly cystic ovarian syndrome (PCOS) is a heterogeneous disorder common among reproductive age women. The study was focused to compare the clinical findings and nutritional status of women with PCOS in 18-29 and 30-45 year age groups. Overall, 120 PCOS subjects in the age group of 18-45 years were selected for the study. Rotterdam criteria was used for identification of the subjects for the study. Socio economic status of the subject revealed that majority of the subjects (49 %) belonged to upper lower class IV. There was a significant mean difference in BMI (p=0.007), Oligo an ovulation (p=0.02) between the two groups. The mean Scores of hirsutism and physical activity was significantly higher in the 18-29 age group (p<0.05). Nutrient intake was assessed by three day food record and food frequency questionnaire (FFQ) and calculated using Diet Cal software. The mean intake of calorie, carbohydrate and fat was remarkably higher in both age groups whereas the intake of micronutrients such as calcium, zinc, iron and retinol was lower compared to EAR. Vitamin D intake was lower than the EAR in all the selected subjects. The comparison of nutritional status of the two age groups disclosed that there was a significantly higher mean intake of calorie (p=0.045), fibre (p=0.006), iron (p=0.022), magnesium (p=0.017), chromium (p=0.016) and potassium (p=0.041) in the 30-45 year age group. Food consumption pattern affirmed that there was a remarkable difference in the intake of processed foods, soft drinks, sweets, fish, leafy vegetables, pickle between the two age groups.","PeriodicalId":22457,"journal":{"name":"The Indian journal of nutrition and dietetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76324996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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