: Presumed sterile eosinophilic and granulomatous mural folliculitis and furunculosis was diagnosed in a goat. Dermatological findings included widespread, nonpruritic, bilaterally symmetrical exudation, crusting, alopecia, and thickened skin. Infectious causes were ruled out by negative histochemical stains and negative PCR for ovine herpesvirus-2 conducted on skin-biopsy specimens. There was a 50% reduction in the severity of the dermatitis with intramuscular injections of dexamethasone. A cause for the skin condition was not determined.
{"title":"Presumed Sterile Eosinophilic and Granulomatous Mural Folliculitis and Furunculosis in an Angora and Pygmy Crossbreed Goat","authors":"R. Ruby, J. Peters-Kennedy, G. Ferguson, D. Scott","doi":"10.2736/jjvd.25.157","DOIUrl":"https://doi.org/10.2736/jjvd.25.157","url":null,"abstract":": Presumed sterile eosinophilic and granulomatous mural folliculitis and furunculosis was diagnosed in a goat. Dermatological findings included widespread, nonpruritic, bilaterally symmetrical exudation, crusting, alopecia, and thickened skin. Infectious causes were ruled out by negative histochemical stains and negative PCR for ovine herpesvirus-2 conducted on skin-biopsy specimens. There was a 50% reduction in the severity of the dermatitis with intramuscular injections of dexamethasone. A cause for the skin condition was not determined.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75489535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kazuaki Akashi, Y. Nakamura, K. Iyori, Takafumi Osumi
: A 13-month-old, intact, male Bengal cat presented with an 8-month history of bilateral earwax accumulation with mild pruritus. Direct microscopy of the earwax showed plenty of live mites, which were morphologically identical to Demodex cati. No other skin lesions were detected on the cat. A spot-on formulation containing 10% imidacloprid and 1% moxidectin was applied on the back 4 times, once every 2 weeks, but the mites did not disappear. Thereafter, a single oral administration of fluralaner (about 41 mg/kg) improved the symptoms, and no mites were detected on direct microscopy 39 days after the administration.
{"title":"A case of localized feline demodicosis in the ear canals, refractory to a spot-on formulation of 10% imidacloprid and 1% moxidectin, successfully treated with oral fluralaner","authors":"Kazuaki Akashi, Y. Nakamura, K. Iyori, Takafumi Osumi","doi":"10.2736/jjvd.25.217","DOIUrl":"https://doi.org/10.2736/jjvd.25.217","url":null,"abstract":": A 13-month-old, intact, male Bengal cat presented with an 8-month history of bilateral earwax accumulation with mild pruritus. Direct microscopy of the earwax showed plenty of live mites, which were morphologically identical to Demodex cati. No other skin lesions were detected on the cat. A spot-on formulation containing 10% imidacloprid and 1% moxidectin was applied on the back 4 times, once every 2 weeks, but the mites did not disappear. Thereafter, a single oral administration of fluralaner (about 41 mg/kg) improved the symptoms, and no mites were detected on direct microscopy 39 days after the administration.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79901951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of cephalic soft tissue sarcoma in a cat treated with toceranib","authors":"Shino Saito, S. Kimura, R. Kano","doi":"10.2736/JJVD.25.077","DOIUrl":"https://doi.org/10.2736/JJVD.25.077","url":null,"abstract":"","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75349079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Venom immunotherapy (VIT) provides an opportunity to reduce life-threatening reactions to venomous insect stings. VIT requires stabilization with human albumin. This report describes a Labrador Retriever that developed anaphylaxis during VIT induction. Intradermal testing (IDT) identified a human albumin hypersensitivity. Four years later, re-testing revealed a persistent hypersensitization to human albumin. To identify if VIT is a risk factor for human albumin sensitivity, IDT was performed in 4 honeybee allergic dogs being treated with VIT, with 6 healthy and 6 atopic dogs as controls. One other dog reacted to human albumin at the testing concentrations. This dog was being treated with VIT but had no clinical manifestations. VIT containing human albumin may lead to sensitization of this protein and anaphylaxis.
{"title":"Anaphylaxis in a canine patient sensitized to human albumin while on honeybee immunotherapy","authors":"Christopher P Hudec, M. Boord, C. Griffin","doi":"10.2736/jjvd.25.143","DOIUrl":"https://doi.org/10.2736/jjvd.25.143","url":null,"abstract":"Venom immunotherapy (VIT) provides an opportunity to reduce life-threatening reactions to venomous insect stings. VIT requires stabilization with human albumin. This report describes a Labrador Retriever that developed anaphylaxis during VIT induction. Intradermal testing (IDT) identified a human albumin hypersensitivity. Four years later, re-testing revealed a persistent hypersensitization to human albumin. To identify if VIT is a risk factor for human albumin sensitivity, IDT was performed in 4 honeybee allergic dogs being treated with VIT, with 6 healthy and 6 atopic dogs as controls. One other dog reacted to human albumin at the testing concentrations. This dog was being treated with VIT but had no clinical manifestations. VIT containing human albumin may lead to sensitization of this protein and anaphylaxis.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"179 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90040235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Shibasaki, Yasutaka Oda, Tomoyuki Suzuki, M. Shibasaki, Humio Shibasaki, K. Iyori
{"title":"Sterile granuloma and pyogranuloma syndrome in two American Pit Bull Terriers","authors":"Y. Shibasaki, Yasutaka Oda, Tomoyuki Suzuki, M. Shibasaki, Humio Shibasaki, K. Iyori","doi":"10.2736/jjvd.25.13","DOIUrl":"https://doi.org/10.2736/jjvd.25.13","url":null,"abstract":"","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77673930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Asahina, Takafumi Osumi, T. Mizuno, Yuri Oshima, M. Kadoya, T. Murai, K. Yamagishi, K. Nishifuji, M. Nagata, S. Maeda
The international clinical guideline for canine atopic dermatitis (CAD) was published by the International Committee on Allergic Diseases of Animals in 2015. Unfortunately, it does not fully cover the situations in Japan due to differences in veterinary practice between Japan and the rest of world. The Guideline Committee of the Japanese Society of Veterinary Dermatology (JSVD) attempted to develop guidelines for the diagnosis and treatment of CAD in 2016 and 2017, respectively. However, these attempts were unsuccessful because of a lack of clinical evidence. The most critical issues identified were the clarification of the clinical features of CAD among the breeds in which it commonly occurs in Japan, and the establishment of new methods for evaluating its severity. In particular, it is important to promote clinical studies supported by JSVD, in order to establish suitable biomarkers that can be used to objectively evaluate the therapeutic effect of treatments for CAD.
{"title":"An attempt to develop guidelines for the diagnosis and treatment of canine atopic dermatitis: current status and issues","authors":"R. Asahina, Takafumi Osumi, T. Mizuno, Yuri Oshima, M. Kadoya, T. Murai, K. Yamagishi, K. Nishifuji, M. Nagata, S. Maeda","doi":"10.2736/JJVD.25.069","DOIUrl":"https://doi.org/10.2736/JJVD.25.069","url":null,"abstract":"The international clinical guideline for canine atopic dermatitis (CAD) was published by the International Committee on Allergic Diseases of Animals in 2015. Unfortunately, it does not fully cover the situations in Japan due to differences in veterinary practice between Japan and the rest of world. The Guideline Committee of the Japanese Society of Veterinary Dermatology (JSVD) attempted to develop guidelines for the diagnosis and treatment of CAD in 2016 and 2017, respectively. However, these attempts were unsuccessful because of a lack of clinical evidence. The most critical issues identified were the clarification of the clinical features of CAD among the breeds in which it commonly occurs in Japan, and the establishment of new methods for evaluating its severity. In particular, it is important to promote clinical studies supported by JSVD, in order to establish suitable biomarkers that can be used to objectively evaluate the therapeutic effect of treatments for CAD.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86702138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shoko Momiyama, Yasushi Nunokawa, Nobuko Nunokawa, Ikeda Hirokazu, A. Kawanishi, K. Iyori
A 7-year-old castrated male Maltese was presented with multicentric erythema, erosion and crust on the face and footpads. A diagnosis of necrolytic migratory erythema (NME) due to hepatic cirrhosis was made following clinical and histopathological examinations. Cutaneous lesions and hypoalbuminemia improved after 32 days of combination treatment of liver support therapy, amino acid fluids, and intravenous adipose-derived stem cells (ADSCs) therapy. Skin lesions and hypoalbuminemia did not recur during 20 months of ADSCs therapy even after withdrawal of amino acid supplementation. These results suggest that ADSCs therapy could be an effective treatment option for canine NME.
{"title":"A Case of Canine Necrolytic Migratory Erythema Treated with Adipose-derived Stem Cells Therapy","authors":"Shoko Momiyama, Yasushi Nunokawa, Nobuko Nunokawa, Ikeda Hirokazu, A. Kawanishi, K. Iyori","doi":"10.2736/jjvd.24.141","DOIUrl":"https://doi.org/10.2736/jjvd.24.141","url":null,"abstract":"A 7-year-old castrated male Maltese was presented with multicentric erythema, erosion and crust on the face and footpads. A diagnosis of necrolytic migratory erythema (NME) due to hepatic cirrhosis was made following clinical and histopathological examinations. Cutaneous lesions and hypoalbuminemia improved after 32 days of combination treatment of liver support therapy, amino acid fluids, and intravenous adipose-derived stem cells (ADSCs) therapy. Skin lesions and hypoalbuminemia did not recur during 20 months of ADSCs therapy even after withdrawal of amino acid supplementation. These results suggest that ADSCs therapy could be an effective treatment option for canine NME.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"32 1","pages":"141-145"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86635807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The efficacy of afoxolaner for canine demodicosis was evaluated in six cases (generalized type: five cases, localized type: one case) of Demodex canis infestation. Afoxolaner was administered orally at the doses of 2.7–5.6 mg/kg of body weight on day 0 and at 3 to 6 week intervals. The administration frequency of afoxolaner required for the disappearance of mites was one time in two cases, two times in three cases, and three times in one case. Cutaneous lesions took 4–12 weeks to heal after initial treatment in all cases. No adverse reactions were recorded in the follow-up with owners, or were found in the physical examination at the reexamination visit during treatment with afoxolaner. In addition, no clinical recurrence was observed in any case in the 6 months in all cases after the final medical examination. On the basis of these results, afoxolaner is effective for the treatment of canine demodicosis.
{"title":"Efficacy of Afoxolaner in Six Cases of Canine Demodicosis","authors":"Y. Iijima, N. Itoh, Y. Kimura","doi":"10.2736/JJVD.24.83","DOIUrl":"https://doi.org/10.2736/JJVD.24.83","url":null,"abstract":"The efficacy of afoxolaner for canine demodicosis was evaluated in six cases (generalized type: five cases, localized type: one case) of Demodex canis infestation. Afoxolaner was administered orally at the doses of 2.7–5.6 mg/kg of body weight on day 0 and at 3 to 6 week intervals. The administration frequency of afoxolaner required for the disappearance of mites was one time in two cases, two times in three cases, and three times in one case. Cutaneous lesions took 4–12 weeks to heal after initial treatment in all cases. No adverse reactions were recorded in the follow-up with owners, or were found in the physical examination at the reexamination visit during treatment with afoxolaner. In addition, no clinical recurrence was observed in any case in the 6 months in all cases after the final medical examination. On the basis of these results, afoxolaner is effective for the treatment of canine demodicosis.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"39 1","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90649936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Fukutomi, N. Yamamoto, H. Kondo, H. Shibuya, T. Watari, R. Kano, H. Kamata
: A 9-year-old female mixed-breed dog presented with alopecia, squama, scaling, erosion, and hyperpigmentation that had persisted for three months. Histopathological assessment of a skin biopsy, bone marrow aspiration, and fine needle aspiration of the liver and spleen revealed lymphocyte hyperplasia. A blood cell count also indicated severe lymphocytosis. These findings were consistent with lymphocytosis accompanied by cutaneous lesions, and not neoplastic proliferation of lymphocytes or any other pathology. The dog was treated with antibiotic, antimycotic, dietary therapy, and interferon therapy, and achieved remission of skin lesion and lymphocytosis on steroid therapy.
{"title":"A Case of Canine Lymphocytosis with a Prominent Skin Lesion","authors":"T. Fukutomi, N. Yamamoto, H. Kondo, H. Shibuya, T. Watari, R. Kano, H. Kamata","doi":"10.2736/JJVD.24.13","DOIUrl":"https://doi.org/10.2736/JJVD.24.13","url":null,"abstract":": A 9-year-old female mixed-breed dog presented with alopecia, squama, scaling, erosion, and hyperpigmentation that had persisted for three months. Histopathological assessment of a skin biopsy, bone marrow aspiration, and fine needle aspiration of the liver and spleen revealed lymphocyte hyperplasia. A blood cell count also indicated severe lymphocytosis. These findings were consistent with lymphocytosis accompanied by cutaneous lesions, and not neoplastic proliferation of lymphocytes or any other pathology. The dog was treated with antibiotic, antimycotic, dietary therapy, and interferon therapy, and achieved remission of skin lesion and lymphocytosis on steroid therapy.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"65 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80201844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Kano, K. Iyori, K. Harada, N. Murayama, M. Yamasaki, K. Makimura, R. Tsuboi, K. Yamagishi, T. Murai, K. Nishifuji, A. Hasegawa, M. Nagata
加納 塁 * 伊從慶太 原田和記 村山信雄 山﨑真大 5) 槇村浩一 坪井良治 山岸建太郎 村井 妙 9) 西藤公司 長谷川篤彦 永田雅彦 12) 日本大学,株式会社 VDT,鳥取大学,犬と猫の皮膚科,岩手大学,帝京大学, 東京医科大学,本郷どうぶつ病院,キンダーケア動物病院,東京農工大学, 東京大学,どうぶつの総合病院 Rui Kano*, Keita Iyori, Kazuki Harada, Nobuo Murayama, Masahiro Yamasaki, Koichi Makimura, Ryoji Tsuboi, Kentaro Yamagishi, Tae Murai, Koji Nishifuji, Atsuhiko Hasegawa, Masahiko Nagata Nihon University, Vet Derm Tokyo, Tottori University, Dermatology Services for Dogs and Cats, Iwate University, Teikyo University, Tokyo Medical University, Nagano Hongo Animal Clinic, Kinder-Care Veterinary Clinic, Tokyo University of Agriculture and Technology, Tokyo University, Synergy Animal General Hospital Dermatology Service
加納 塁 * 伊從慶太 原田和記 村山信雄 山﨑真大 5) 槇村浩一 坪井良治 山岸建太郎 村井 妙 9) 西藤公司 長谷川篤彦 永田雅彦 12) 日本大学,株式会社 VDT,鳥取大学,犬と猫の皮膚科,岩手大学,帝京大学, 東京医科大学,本郷どうぶつ病院,キンダーケア動物病院,東京農工大学, 東京大学,どうぶつの総合病院 Rui Kano*, Keita Iyori, Kazuki Harada, Nobuo Murayama, Masahiro Yamasaki, Koichi Makimura, Ryoji Tsuboi, Kentaro Yamagishi, Tae Murai, Koji Nishifuji, Atsuhiko Hasegawa, Masahiko Nagata Nihon University, Vet Derm Tokyo, Tottori University, Dermatology Services for Dogs and Cats, Iwate University, Teikyo University, Tokyo Medical University, Nagano Hongo Animal Clinic, Kinder-Care Veterinary Clinic, Tokyo University of Agriculture and Technology, Tokyo University, Synergy Animal General Hospital Dermatology Service
{"title":"Canine and Feline Dermatophyosis: a Guideline for the Antifungal Therapy","authors":"R. Kano, K. Iyori, K. Harada, N. Murayama, M. Yamasaki, K. Makimura, R. Tsuboi, K. Yamagishi, T. Murai, K. Nishifuji, A. Hasegawa, M. Nagata","doi":"10.2736/JJVD.24.3","DOIUrl":"https://doi.org/10.2736/JJVD.24.3","url":null,"abstract":"加納 塁 * 伊從慶太 原田和記 村山信雄 山﨑真大 5) 槇村浩一 坪井良治 山岸建太郎 村井 妙 9) 西藤公司 長谷川篤彦 永田雅彦 12) 日本大学,株式会社 VDT,鳥取大学,犬と猫の皮膚科,岩手大学,帝京大学, 東京医科大学,本郷どうぶつ病院,キンダーケア動物病院,東京農工大学, 東京大学,どうぶつの総合病院 Rui Kano*, Keita Iyori, Kazuki Harada, Nobuo Murayama, Masahiro Yamasaki, Koichi Makimura, Ryoji Tsuboi, Kentaro Yamagishi, Tae Murai, Koji Nishifuji, Atsuhiko Hasegawa, Masahiko Nagata Nihon University, Vet Derm Tokyo, Tottori University, Dermatology Services for Dogs and Cats, Iwate University, Teikyo University, Tokyo Medical University, Nagano Hongo Animal Clinic, Kinder-Care Veterinary Clinic, Tokyo University of Agriculture and Technology, Tokyo University, Synergy Animal General Hospital Dermatology Service","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"56 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73783868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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