: A 4-year-old female rabbit presented with two nodular lesions on the left side of the abdomen, adjacent to the femoral region. No surgical operation was done because a malignant skin neoplasm with poor prognosis was suspected. The appetite of the rabbit gradually decreased and the rabbit died 41 days after this presentation. The two nodules rapidly increased and fused into a single large oval mass. Histopathologically, round, spindle-shaped and pleomorphic tumor cells were observed. These tumor cells showed atypical nuclei with mitotic figures and some were multinucleated. Immunohistochemical analysis revealed that the tumor cells were positive for vimentin and α-smooth muscle actin, but negative for cytokeratin and desmin. Consequently, this case was diagnosed as cutaneous pleomorphic leiomyosarcoma.
{"title":"Cutaneous pleomorphic leiomyosarcoma in a rabbit","authors":"Yoshihiko Sato, Ryohei Sato","doi":"10.2736/jjvd.24.207","DOIUrl":"https://doi.org/10.2736/jjvd.24.207","url":null,"abstract":": A 4-year-old female rabbit presented with two nodular lesions on the left side of the abdomen, adjacent to the femoral region. No surgical operation was done because a malignant skin neoplasm with poor prognosis was suspected. The appetite of the rabbit gradually decreased and the rabbit died 41 days after this presentation. The two nodules rapidly increased and fused into a single large oval mass. Histopathologically, round, spindle-shaped and pleomorphic tumor cells were observed. These tumor cells showed atypical nuclei with mitotic figures and some were multinucleated. Immunohistochemical analysis revealed that the tumor cells were positive for vimentin and α-smooth muscle actin, but negative for cytokeratin and desmin. Consequently, this case was diagnosed as cutaneous pleomorphic leiomyosarcoma.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"27 1","pages":"207-210"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90933694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Clasification of Dermatophytes","authors":"R. Kano","doi":"10.2736/JJVD.24.9","DOIUrl":"https://doi.org/10.2736/JJVD.24.9","url":null,"abstract":"","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"1 1","pages":"9-12"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75324845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naoko Arikawa, J. Chambers, Kohtaro Hayashi, K. Uchida, Takuro Kariya
Here we describe the clinical and pathological findings of a 15-year-old cat with multiple cutaneous tumors including Merkel cell carcinoma. The cat was presented with a cutaneous mass in the lumbar region which was histopathologically diagnosed as Merkel cell carcinoma with lymph node metastasis. Multifocal cutaneous lesions were also observed in the dorsal region. They were histopathologically diagnosed as Bowenoid in situ carcinoma, basal cell carcinoma, and cutaneous mast cell tumor. The cat died 154 days after initial presentation, and autopsy revealed metastatic lesions of Merkel cell carcinoma in the pelvic cavity. This report describes the detailed autopsy and histopathological findings of a feline Merkel cell carcinoma accompanied by various other cutaneous tumors.
{"title":"Multiple Cutaneous Tumors including Merkel Cell Carcinoma in a Cat","authors":"Naoko Arikawa, J. Chambers, Kohtaro Hayashi, K. Uchida, Takuro Kariya","doi":"10.2736/JJVD.24.77","DOIUrl":"https://doi.org/10.2736/JJVD.24.77","url":null,"abstract":"Here we describe the clinical and pathological findings of a 15-year-old cat with multiple cutaneous tumors including Merkel cell carcinoma. The cat was presented with a cutaneous mass in the lumbar region which was histopathologically diagnosed as Merkel cell carcinoma with lymph node metastasis. Multifocal cutaneous lesions were also observed in the dorsal region. They were histopathologically diagnosed as Bowenoid in situ carcinoma, basal cell carcinoma, and cutaneous mast cell tumor. The cat died 154 days after initial presentation, and autopsy revealed metastatic lesions of Merkel cell carcinoma in the pelvic cavity. This report describes the detailed autopsy and histopathological findings of a feline Merkel cell carcinoma accompanied by various other cutaneous tumors.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"1 1","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79826057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Uchida, Y. Sonoda, Azusa Kumakura, I. Kanai, A. Imai, M. Nagata
: A 1-year-old, spayed female Himalayan cat presented with traumatic alopecia at the flanks, the cauda and the precordia. Palpation induced excessive licking behavior over the trunk. The cat was treated with glucocorticoids, selective serotonin reuptake inhibitors, and a neuropathic pain agent. The lesions improved, but relapsed with cessation of glucocorticoids. Then Demodex gatoi was detected in the scaly alopecia, and oral fluralaner was administered. The alopecia improved and tests for D. gatoi became negative after 2 months. The medications were withdrawn, and the traumatic alopecia relapsed. It was cured by the reintroduction of fluoxetine and pregabalin, as well as administration of fluralaner every 3 months. Finally, no glucocorticoids and fluralaner were required. The relationship between D. gatoi infection and feline hyperesthesia syndrome is discussed.
{"title":"Demodex gatoi infestation-associated traumatic alopecia in a Himalayan cat","authors":"N. Uchida, Y. Sonoda, Azusa Kumakura, I. Kanai, A. Imai, M. Nagata","doi":"10.2736/JJVD.24.211","DOIUrl":"https://doi.org/10.2736/JJVD.24.211","url":null,"abstract":": A 1-year-old, spayed female Himalayan cat presented with traumatic alopecia at the flanks, the cauda and the precordia. Palpation induced excessive licking behavior over the trunk. The cat was treated with glucocorticoids, selective serotonin reuptake inhibitors, and a neuropathic pain agent. The lesions improved, but relapsed with cessation of glucocorticoids. Then Demodex gatoi was detected in the scaly alopecia, and oral fluralaner was administered. The alopecia improved and tests for D. gatoi became negative after 2 months. The medications were withdrawn, and the traumatic alopecia relapsed. It was cured by the reintroduction of fluoxetine and pregabalin, as well as administration of fluralaner every 3 months. Finally, no glucocorticoids and fluralaner were required. The relationship between D. gatoi infection and feline hyperesthesia syndrome is discussed.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"83 1","pages":"211-214"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83790581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Superficial Pyoderma Improved by Shampoo Therapy Containing 1% of Isopropylmethylphenol in Dog","authors":"R. Kono, Hirotaka Watanabe, Takafumi Osumi","doi":"10.2736/JJVD.24.153","DOIUrl":"https://doi.org/10.2736/JJVD.24.153","url":null,"abstract":"","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"15 1","pages":"153-155"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84389951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fumio Suetsugu, T. Kawakita, S. Matsuo, K. Shirota
A 12-year-old male domestic short-hair cat was presented with a sudden laceration of the lumbar skin. The lumbar skin showed irregular tears and shedding as a large sheet. Histopathological examination of the skin revealed atrophic epidermis with hyperkeratosis, and decreased and fragmented collagen fibers in the dermis. A diagnosis of acquired skin fragility syndrome was consequently made. The present case died of asthenia with an eating disorder due to a large mandibular abscess. Necropsy and histopathological examination revealed that the cat had cholangiohepatitis, membranoproliferative glomerulonephritis, and intestinal villi fibrosis as complications of the skin lesion. Clinical improvement of the skin lesion was found after treatment with a digestive enzyme compound agent administered in consideration of the malabsorption. Therefore, malabsorption might be closely related to the skin lesion of the present case.
{"title":"Acquired Skin Fragility Syndrome with Malabsorption, Protein-losing Glomerulonephritis and Cholangiohatitis in a Cat","authors":"Fumio Suetsugu, T. Kawakita, S. Matsuo, K. Shirota","doi":"10.2736/JJVD.24.73","DOIUrl":"https://doi.org/10.2736/JJVD.24.73","url":null,"abstract":"A 12-year-old male domestic short-hair cat was presented with a sudden laceration of the lumbar skin. The lumbar skin showed irregular tears and shedding as a large sheet. Histopathological examination of the skin revealed atrophic epidermis with hyperkeratosis, and decreased and fragmented collagen fibers in the dermis. A diagnosis of acquired skin fragility syndrome was consequently made. The present case died of asthenia with an eating disorder due to a large mandibular abscess. Necropsy and histopathological examination revealed that the cat had cholangiohepatitis, membranoproliferative glomerulonephritis, and intestinal villi fibrosis as complications of the skin lesion. Clinical improvement of the skin lesion was found after treatment with a digestive enzyme compound agent administered in consideration of the malabsorption. Therefore, malabsorption might be closely related to the skin lesion of the present case.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"29 1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89275830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Hada, Kyouichi Tamura, H. Orima, T. Komatsu, T. Ishimura, K. Orito, M. Nagata
We report two dogs with Zonisamide adverse drug reactions. Case 1, a 6-year-old, intact, female Maltese presented with erythroderma, and case 2, a 10-year-old, castrated, male miniature Pinscher showed erythema multiforme-toxic epidermolytic necrolysis. Both cases were suspected of having adverse drug reactions to Zonisamide based on their symptoms, blood test results and histopathologic findings. The eruptions completely disappeared with cessation of Zonisamide. A lymphocyte transformation test was carried out on both cases, but no positive reactions were seen. Further investigation of adverse reaction to Zonisamide, especially its incidence and pathogenesis, with more cases will be needed.
{"title":"Adverse drug reactions to Zonisamide in two dogs.","authors":"M. Hada, Kyouichi Tamura, H. Orima, T. Komatsu, T. Ishimura, K. Orito, M. Nagata","doi":"10.2736/JJVD.24.147","DOIUrl":"https://doi.org/10.2736/JJVD.24.147","url":null,"abstract":"We report two dogs with Zonisamide adverse drug reactions. Case 1, a 6-year-old, intact, female Maltese presented with erythroderma, and case 2, a 10-year-old, castrated, male miniature Pinscher showed erythema multiforme-toxic epidermolytic necrolysis. Both cases were suspected of having adverse drug reactions to Zonisamide based on their symptoms, blood test results and histopathologic findings. The eruptions completely disappeared with cessation of Zonisamide. A lymphocyte transformation test was carried out on both cases, but no positive reactions were seen. Further investigation of adverse reaction to Zonisamide, especially its incidence and pathogenesis, with more cases will be needed.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"144 1","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78161314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Canine Skin Deficiency Treatment with the β-chitin Nanofiber Ointment","authors":"R. Kano, A. Kajikawa, M. Kitagawa, H. Kamata","doi":"10.2736/JJVD.24.17","DOIUrl":"https://doi.org/10.2736/JJVD.24.17","url":null,"abstract":"","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"46 16","pages":"17-18"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91464602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：