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猫胸部側背面から採材した健常皮膚の真皮におけるCD3+およびPax5+リンパ球 从猫胸部背面采材的健康皮肤的真皮层中的CD3+和Pax5+淋巴细胞
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.5
Daniel C. Fickle, D. Scott, J. Peters-Kennedy
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引用次数: 0
犬アトピー性皮膚炎の急性期におけるオクラシチニブマレイン酸塩と組換え型コナヒョウヒダニアレルゲンDer f 2-プルラン結合体の併用療法 狗患特应性皮肤炎急性期的褐黄曲菌碱与重组型粉表皮变应原Der f 2- plan结合体的联合疗法
Pub Date : 2017-01-01 DOI: 10.2736/jjvd.23.189
大池 美和子, 昭宏 今井, 薫 吉池, 尚廉 高畑, 雅彦 永田
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引用次数: 0
Mohs Gauze Method Drastically Reduced the Volume of a Ruptured Mammary Gland Tumor in a Miniature Dachshund 莫氏纱布法大大减少了小型腊肠犬破裂乳腺肿瘤的体积
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.57
A. Shimizu
Mohs paste is used for the management of malignant skin tumors, with bleeding, exudate and malodor. Mohs paste is usually directly applied to skin lesions but is difficult to use because of its high viscosity and tackiness. For use with humans, Mohs gauze method, which is modified Mohs paste method that spread past on gauze, was invented for ease of use on skin lesions. In this study, we used Mohs gauze method to treat an unresectable ruptured mammary gland tumor in a miniature dachshund. We succeeded in drastically reducing the tumor volume. Thus, this method can be used for many shapes of tumor in various animal cases.
莫氏膏用于治疗伴有出血、渗出和恶臭的恶性皮肤肿瘤。莫氏膏通常直接应用于皮肤损伤,但由于其高粘度和粘性而难以使用。为了便于人体使用,发明了莫氏纱布法。莫氏纱布法是将涂抹在纱布上的莫氏膏状方法进行改良,用于皮肤病变部位。本研究采用莫氏纱布法治疗小型腊肠犬不可切除的乳腺肿瘤破裂。我们成功地大大缩小了肿瘤的体积。因此,该方法可用于各种动物病例中多种形状的肿瘤。
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引用次数: 1
Prevalence of Dermatophytes in Pet Shop Young Cats 宠物店幼猫皮肤真菌的流行
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.69
N. Itoh, M. Suda, Y. Iijima, Yoichi Ito, Phrompraphai Totsapon, Y. Kimura
The present study determined the prevalence of dermatophytes in 101 young cats with and without skin lesions, in eight pet shops using a culture method. Dermatophytes were detected in four cats (4.0%), suggesting that the prevalence of dermatophytes is not high among pet shop young cats in Japan. Only one of the four cats with dermatophytes showed a cutaneous lesion. All of the isolated dermatophytes were identified as Microsporum canis by direct sequencing of amplicons obtained from PCR targeting the region including ITS-1 of the rRNA gene.
本研究在8家宠物店用培养法测定了101只有和没有皮肤损伤的年轻猫的皮肤真菌的流行情况。在4只猫中检测到皮肤癣菌(4.0%),表明日本宠物店幼猫中皮肤癣菌的患病率不高。4只患皮癣的猫中只有1只出现了皮肤损伤。所有分离的皮肤真菌均为犬小孢子菌(Microsporum canis),通过对rRNA基因ITS-1等区域的PCR扩增子进行直接测序。
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引用次数: 1
Canine Superficial Pyoderma: an Indication for Antimicrobial and Topical Therapies 犬浅表性脓皮病:抗菌剂和局部治疗的适应症
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.127
M. Yamasaki, R. Kano, K. Harada, N. Murayama, Takashi Sasaki, K. Orito, H. Kondo, T. Murai, K. Yamagishi, K. Nishifuji, M. Nagata
Canine superficial pyoderma is mainly caused by Staphylococcus pseudintermedius and S. schleiferi on and/or in the epidermis dermis and the follicle. Due to the increased frequency of the isolation of drug-resistant bacteria from skin lesions, therapy for canine superficial pyoderma has become highly complicated. Accordingly, the Guideline Committee of the Japanese Society of Veterinary Dermatology has attempted to develop a guideline for the treatment of canine superficial pyoderma in Japanese veterinary practice. We referred to reviews and guidelines concerning canine skin infection which were mainly published in the US and European countries, and collected additional papers. Based on the findings, it is difficult to propose a guideline for Japanese practitioners at this moment, since evidence for the practice is quite limited. Through this research, we have gained an understanding of the current problems concerning therapies for 総 説 * 連絡先:山﨑真大(岩手大学) 〒 020-8550 岩手県盛岡市上田 3丁目 18-8 岩手大学農学部 TEL/FAX 019-621-6235 E-mail: masayama@iwate-u.ac.jp * Correspondence to: Masahiro Yamasaki (Iwate University) Faculty of Agriculture, Iwate University, 18-8, Ueda 3, Morioka, Iwate 020-8550, Japan
犬浅表性脓皮病主要由假中间葡萄球菌和施莱氏葡萄球菌在表皮、真皮和毛囊上和/或内引起。由于从皮肤病变中分离出耐药细菌的频率增加,犬浅表性脓皮病的治疗变得非常复杂。因此,日本兽医皮肤病学会指导委员会试图制定日本兽医实践中犬浅表性脓皮病的治疗指南。我们参考了主要在美国和欧洲国家发表的关于犬类皮肤感染的综述和指南,并收集了额外的论文。基于这些发现,目前很难为日本从业者提出指导方针,因为实践的证据相当有限。通过本研究,我们了解了目前有关治疗方法的问题:含有:020-8550,含有:020-8550,含有:020-8550,含有:019-621-6235,含有:019-621-6235,含有:019-621-6235,电子邮件:masayama@iwate-u.ac.jp,通讯作者:Masahiro Yamasaki(岩手大学)岩手大学农业学院,18-8,上田3,森冈,岩手020-8550,日本
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引用次数: 1
Skin Tumor Consisting of Intermingled Lipoma and Extramedullary Plasmacytoma in an Old Dog 老年犬的皮肤肿瘤,由混合性脂肪瘤和髓外浆细胞瘤组成
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.139
H. Hyogo, T. Ohmuro, James Chembers, J. Kamiie, K. Shirota
* Correspondence to: Kinji Shirota (Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University), Fuchinobe 1-17-71, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan TEL +81-42-850-2468 FAX +81-42-769-1628 E-mail: shirota@azabu-u.ac.jp A cutaneous solitary soft neoplasm of approximately 20 mm in diameter developed on the back of a 14-yearold male mongrel dog (Fig. 1). Cytologic examination of a fine-needle biopsy of the neoplasm revealed round tumor cells with eccentric nuclei and occasional perinuclear halos. No significant clinical symptoms were found in the dog. The neoplasm was resected under local anesthesia. The mass lesion was easily separated from the adjacent subcutaneous tissue, and the gross appearance of the cut surface was shiny and similar to lipoma (Fig. 2). The resected neoplasm was fixed in 10% neutral buffered formalin, in which it floated, and was then submitted to our laboratory for histologic examination. Histologically, a major portion of the neoplasm consisted of a lipomatous structure composed of mature adipocytes with a small distinct proliferating focus of closely packed neoplastic plasmacytoid cells (Fig. 3). The well-demarcated lipomatous structure was surrounded by thin collagen fibers. In addition, the neoplastic plasmacytoid cells had diffusely infiltrated within and around the lipomatous structure (Fig. 4). The neoplastic plasmacytoid cells showed mild anisokaryosis and frequent mitosis, especially in the proliferating focus. Many of the neoplastic plasmacytoid cells infiltrating between the adipocytes had a fine vacuolar cytoplasm. Immunostaining revealed that the cytoplasm of most of the neoplastic plasmacytoid cells was positive for the lambda light chain of immunoglobulin, but negative for the kappa light chain of immunoglobulin (Fig. 4), suggesting monoclonal proliferation of the plasma cells. From these histologic findings, the tumor was diagnosed as a benign collision tumor of the skin that consisted of lipoma and extramedullary plasmacytoma. A collision tumor is defined as a tumor in which the neoplastic proliferation of cells from two originally different cell lineages occurs in close proximity in the same tumor tissue. Collision tumors are rare in dogs, although malignant collision tumors in the skin and
*通讯对象:日本神奈川县相模原市中央区富庶部1-17-71,麻abu大学兽医学院兽医病理学实验室,电话+81-42-850-2468传真+81-42-769-1628电子邮件:shirota@azabu-u.ac.jp 14岁雄性杂种狗背部发生皮肤孤立性软肿瘤,直径约20mm(图1)。肿瘤细针活检的细胞学检查显示圆形肿瘤细胞,细胞核偏心,偶尔有核周晕。未发现明显的临床症状。在局部麻醉下切除肿瘤。肿块病灶很容易与邻近皮下组织分离,切面大体外观有光泽,与脂肪瘤相似(图2)。将切除的肿瘤固定在10%中性缓冲福尔马林中,使其漂浮,然后提交我们的实验室进行组织学检查。组织学上,肿瘤的主要部分是由成熟脂肪细胞组成的脂肪瘤结构,并有一个小而明显的增生灶,肿瘤浆细胞样细胞紧密堆积(图3)。界限清晰的脂肪瘤结构被薄的胶原纤维包围。此外,肿瘤浆细胞样细胞弥漫性浸润在脂肪瘤结构内部和周围(图4)。肿瘤浆细胞样细胞表现为轻度异核症和频繁的有丝分裂,特别是在增殖灶。许多浸润在脂肪细胞之间的肿瘤浆细胞样细胞具有细的空泡细胞质。免疫染色显示大多数肿瘤浆细胞样细胞细胞质中免疫球蛋白λ轻链阳性,而免疫球蛋白kappa轻链阴性(图4),提示浆细胞单克隆增殖。根据这些组织学结果,诊断为一良性皮肤碰撞瘤,由脂肪瘤和髓外浆细胞瘤组成。碰撞瘤是指来自两种不同细胞系的细胞在同一肿瘤组织中近距离发生肿瘤增殖的肿瘤。碰撞瘤在狗身上是罕见的,尽管恶性碰撞瘤在皮肤和
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引用次数: 0
シャンプー後に全身症状を伴った皮膚病変を呈したウェルッシュ・コーギー・ペンブロークの3例 三例welsh cogi penbrok洗头后出现全身症状的皮肤病变
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.135
石川 乃梨子, 武志 道本
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引用次数: 0
Successful management with pentosane polysulfate sodium of hyperhidrosis in a dog 戊糖聚硫酸钠治疗犬多汗症的成功治疗
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.185
M. Uchida, T. Kawakami, S. Kawakami, M. Nagata
: A nine-year-old, spayed female Miniature Schnauzer presented with pruritic behavior on the trunk. The dog had had the behavior since her infancy, and it was exacerbated mainly during summer. The dog showed body wetness presumably due to sweating along with scales, papules, erythema, and alopecia over the body. The skin extension index was 16.6 percent. No abnormality was found in hair examinations or skin scrapings. A histopathologic examination revealed remarkably dilated apocrine glands, as well as follicular atrophy and disorganization of the pale-staining connective tissue. Sweat gland dilation and excessive sweating related to connective tissue fragility was suspected. The dog was treated with pentosane polysulfate sodium, a therapeutic agent for osteoarticular disease in dogs, and body wetness and pruritus were almost eliminated.
:一只九岁的雌性迷你雪纳瑞犬,在躯干上表现出瘙痒行为。这只狗从小就有这种行为,主要在夏天加剧。狗表现出身体湿润,可能是由于出汗以及全身的鳞片,丘疹,红斑和脱发。皮肤延伸指数为16.6%。毛发检查及皮肤刮擦未见异常。组织病理学检查显示大汗腺明显扩张,以及滤泡萎缩和淡色结缔组织紊乱。怀疑与结缔组织脆弱有关的汗腺扩张和过度出汗。用犬骨关节疾病治疗剂戊糖聚硫酸钠治疗,犬体湿和瘙痒几乎消除。
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引用次数: 0
Prevalence of Dermatophytes in Private Household Cats 私人家庭猫皮肤癣的流行
Pub Date : 2017-01-01 DOI: 10.2736/JJVD.23.9
N. Itoh, H. Kato, Yoichi Ito, Noriko Oozasa, Y. Kimura, K. Kanai
: The present study determined the prevalence of dermatophytes 216 private household cats with or without skin lesions, using a culture method. Dermatophytes were detected in three cats (1.4%). The prevalence did not significantly differ according to cutaneous lesion (with or without), age (< 1 year old or ≥ 1 year old), outside activity (positive or negative), or hair condition (short hair or long hair). All of the isolated dermatophytes were identified as Microsporum canis through direct sequencing of amplicons obtained from PCR targeting the chitin synthase 1 gene.
本研究采用培养法测定了216只有或无皮肤病变的私人家庭猫的皮肤癣菌的患病率。3只猫(1.4%)检出皮肤癣菌。根据皮肤病变(有无)、年龄(< 1岁或≥1岁)、外部活动(阳性或阴性)或头发状况(短发或长发),患病率无显著差异。所有分离的皮菌均为犬小孢子菌(Microsporum canis),通过PCR获得的几丁质合成酶1基因扩增子直接测序。
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引用次数: 1
Re-evaluation of the Cefovecin Disk Diffusion Test for Predicting Oxacillin-resistance in Staphylococcus pseudintermedius Isolated from Dogs 头孢霉素圆盘扩散试验预测犬假中葡萄球菌耐奥西林的再评价
Pub Date : 2017-01-01 DOI: 10.2736/jjvd.23.73
Y. Terai, Y. Noguchi, K. Iyori, K. Ide, T. Iwasaki, T. Sudo, K. Nishifuji
The aim of this study was to re-evaluate the breakpoint of the cefovecin (CFV) disk diffusion test for predicting oxacillin (MPIPC)-resistance in Staphylococcus pseudintermedius isolated from dogs with pyoderma or healthy dogs. There was a significant positive correlation between CFV and the MPIPC disk diffusion zone diameters. The receiver operating characteristic curve revealed that the best CFV breakpoint for predicting MPIPC resistance was ≦ 25 mm. The concordance rate of the susceptibility and resistance to CFV and MPIPC in S. pseudintermedius was 96.9%. In summary, the CFV disk diffusion test with the newly estimated breakpoint is valid for the prediction of MPIPC-resistance in S. pseudintermedius.
本研究的目的是重新评估cefovecin (CFV)磁盘扩散试验的断点,以预测从脓皮病犬和健康犬分离的假中间葡萄球菌对oxacillin (MPIPC)的耐药性。CFV与MPIPC盘扩散区直径呈显著正相关。接收机工作特性曲线显示,预测MPIPC电阻的最佳CFV断点为≦25 mm。假中间链球菌对CFV和MPIPC的敏感性和耐药性一致性为96.9%。综上所述,基于新估计断点的CFV盘扩散试验可有效预测假中间菌对mpipc的耐药性。
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引用次数: 0
期刊
The Japanese Journal of Veterinary Dermatology
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