首页 > 最新文献

Ibrahim Medical College Journal最新文献

英文 中文
Trends Of Antibiotic Susceptibility Of Salmonella Enterica Serovar Typhi And Paratyphi In An Urban Hospital Of Dhaka City Over 6 Years Period 达喀市某城市医院6年肠道沙门氏菌血清型伤寒和副伤寒药敏趋势
Pub Date : 2012-03-12 DOI: 10.3329/IMCJ.V5I2.10097
K. Shadia, Shajeda Binte Borhan, H. Hasin, S. Rahman, S. Sultana, L. Barai, MS Alam Jilani, J. Haq
The antibiotic resistance pattern of salmonella is ever changing over time. The present study is a retrospective analysis of rate of isolation of Salmonella Typhi and Paratyphi and their antibiotic resistance pattern over 6 years period in an urban hospital of Dhaka city. Blood culture submitted in BIRDEM hospital from 2004-2009 were analyzed. Isolated Salmonella sp were identified and antimicrobial susceptibility testing was carried out by a standard disc diffusion method. Among 385 isolated Salmonella sp 304 (79%) were Salmonella enterica serovar Typhi and 81 (21%) were Salmonella enterica serover Paratyphi A. The rate of isolation of S. Paratyphi A has increased over 6 the year period from 14% to 24%. Resistance to individual first line anti-salmonella drugs has increased from 2004 to 2006 (42 to 63%) but has decreased thereafter. Similar pattern was found when simultaneous resistance to three first line antibiotics namely ampicillin, chloramphenicol and co-trimoxazole were considered. Out of total 304 S. Typhi, 117 (38%) were simultaneously resistant to all three first line drugs compared to only 1.8% S. Paratyphi A. Analysis showed that 80 to 90% of isolated S. Typhi was nalidixic acid resistant (NARST) with reduced susceptibility to ciprofloxacin while the rate for S. Paratyphi A was 71-94%. All S. Typhi and Paratyphi A were sensitive to ceftriaxone. The study showed that there was a gradual decline of resistance of S. Typhi to first line antibiotics but very high prevalence of nalidixic acid resistant S. Typhi and S . Paratyphi in Bangladesh. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10097 IMCJ 2011; 5(2): 42-45
随着时间的推移,沙门氏菌的抗生素耐药性模式一直在变化。本研究回顾性分析了达卡市某城市医院6年来伤寒沙门菌和副伤寒沙门菌的分离率及其抗生素耐药模式。对2004-2009年BIRDEM医院提交的血培养进行分析。对分离的沙门氏菌进行鉴定,采用标准的圆盘扩散法进行药敏试验。在385株分离的沙门氏菌中,304株(79%)为血清型伤寒沙门氏菌,81株(21%)为血清型副伤寒沙门氏菌,副伤寒沙门氏菌的分离率在6年间从14%上升到24%。从2004年到2006年,对个别一线抗沙门氏菌药物的耐药性有所增加(42%至63%),但此后有所下降。同时考虑氨苄西林、氯霉素和复方新诺明三种一线抗生素的耐药情况也类似。在304株伤寒沙门氏菌中,117株(38%)同时对所有3种一线药物耐药,而副伤寒沙门氏菌的这一比例仅为1.8%。分析表明,80 ~ 90%的分离伤寒沙门氏菌对萘啶酸耐药(NARST),对环丙沙星的敏感性降低,而甲型副伤寒沙门氏菌的这一比例为71 ~ 94%。所有伤寒沙门氏菌和甲型副伤寒沙门氏菌均对头孢曲松敏感。研究表明,伤寒沙门氏菌对一线抗生素的耐药性逐渐下降,但耐钠地酸的伤寒沙门氏菌和耐钠地酸的伤寒沙门氏菌的患病率很高。孟加拉的副伤寒。DOI: http://dx.doi.org/10.3329/imcj.v5i2.10097 IMCJ 2011;5(2):使
{"title":"Trends Of Antibiotic Susceptibility Of Salmonella Enterica Serovar Typhi And Paratyphi In An Urban Hospital Of Dhaka City Over 6 Years Period","authors":"K. Shadia, Shajeda Binte Borhan, H. Hasin, S. Rahman, S. Sultana, L. Barai, MS Alam Jilani, J. Haq","doi":"10.3329/IMCJ.V5I2.10097","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I2.10097","url":null,"abstract":"The antibiotic resistance pattern of salmonella is ever changing over time. The present study is a retrospective analysis of rate of isolation of Salmonella Typhi and Paratyphi and their antibiotic resistance pattern over 6 years period in an urban hospital of Dhaka city. Blood culture submitted in BIRDEM hospital from 2004-2009 were analyzed. Isolated Salmonella sp were identified and antimicrobial susceptibility testing was carried out by a standard disc diffusion method. Among 385 isolated Salmonella sp 304 (79%) were Salmonella enterica serovar Typhi and 81 (21%) were Salmonella enterica serover Paratyphi A. The rate of isolation of S. Paratyphi A has increased over 6 the year period from 14% to 24%. Resistance to individual first line anti-salmonella drugs has increased from 2004 to 2006 (42 to 63%) but has decreased thereafter. Similar pattern was found when simultaneous resistance to three first line antibiotics namely ampicillin, chloramphenicol and co-trimoxazole were considered. Out of total 304 S. Typhi, 117 (38%) were simultaneously resistant to all three first line drugs compared to only 1.8% S. Paratyphi A. Analysis showed that 80 to 90% of isolated S. Typhi was nalidixic acid resistant (NARST) with reduced susceptibility to ciprofloxacin while the rate for S. Paratyphi A was 71-94%. All S. Typhi and Paratyphi A were sensitive to ceftriaxone. The study showed that there was a gradual decline of resistance of S. Typhi to first line antibiotics but very high prevalence of nalidixic acid resistant S. Typhi and S . Paratyphi in Bangladesh. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10097 IMCJ 2011; 5(2): 42-45","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114221284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Knowledge, Attitude And Practice Of Hypercholesterolemic Type 2 Diabetic Subjects On Dyslipidemia 高胆固醇血症2型糖尿病患者对血脂异常的认识、态度与实践
Pub Date : 2012-03-12 DOI: 10.3329/IMCJ.V5I2.10096
F. Saleh, S. Mumu, F. Afnan, L. Ali, H. Chaudhury, A. Akhter, K. Ahmed, Sanzida Akter
This study was undertaken to assess the knowledge, attitude and practice (KAP) of hypercholesterolemic type 2 diabetic subjects on dyslipidemia and to analyze the influence of some demographic and socioeconomic factors on the level of KAP.It was a descriptive cross-sectional survey. One hundred eleven newly diagnosed type 2 diabetic subjects (male 61%, female 39%, age 45±9 years, BMI 24±4.8 Kg/m 2 ) with hypercholesterolemia (fasting plasma total cholesterol >200 mg/dl) were selected from the out patient department of BIRDEM by purposive sampling method. Data were collected by a pre-designed, pretested, interviewer-administered questionnaire. Three categories were defined on the basis of the score obtained by each subject namely low, medium and high as follows: knowledge-score 60%; attitude-score 80%; and practice-score 70% respectively. The levels of knowledge were low in 42%, medium in 35% and high in 23% of the study subjects. The corresponding attitude levels were low in 1%, medium in 31% and high in 68%, and the levels of practice were low in 80%, medium in 14% and high in 6% of the subjects. The knowledge score was higher in secondary and graduate (53.4±8.9%, and 54.9±10.1%) groups compared to illiterate-primary group (48.9±9.9%). Practice score of illiterate-primary group (34.5±16.8%) was lower than secondary and graduate (43.1±13.9% and 46.7±18.1%) groups, but they did not differ on attitude. The various income groups did not differ on knowledge. Attitude score of high-income group (78.7±8.4%) was better than low-income group (70.9±11.8%). Practice score in high-income group (44.7±16.0%) was better than medium income and low-income groups (31.3±14.5% and 28.6±15.0%). Knowledge and practice score in Bangladeshi hypercholesterolemic type 2 diabetic subjects are not satisfactory although they have fairly good attitude levels. Education and income status are the major determinants of knowledge, attitude and practice regarding dyslipidemia in diabetes. A coordinated policy is required to promote knowledge and attitude on healthy lifestyle and to translate those into practice. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10096 IMCJ 2011; 5(2): 37-41
本研究旨在评估高胆固醇血症2型糖尿病患者对血脂异常的知识、态度和行为(KAP),并分析一些人口统计学和社会经济因素对KAP水平的影响。这是一个描述性的横断面调查。采用目的抽样的方法,选取我院门诊部高胆固醇血症(空腹血浆总胆固醇>200 mg/dl)的新诊断2型糖尿病患者111例(男性61%,女性39%,年龄45±9岁,BMI 24±4.8 Kg/ m2)。数据通过预先设计、预先测试、访谈者管理的问卷收集。根据每个科目获得的分数分为低、中、高三类:知识- 60%;态度值80%;和实践得分分别为70%。42%的研究对象知识水平低,35%的研究对象知识水平中等,23%的研究对象知识水平高。相应的态度水平为低1%、中31%、高68%;实践水平为低80%、中14%、高6%。中学和大学文盲组的知识得分分别为53.4±8.9%和54.9±10.1%,高于小学文盲组(48.9±9.9%)。文盲小学组的实践得分(34.5±16.8%)低于中学组(43.1±13.9%)和研究生组(46.7±18.1%),但在态度上无差异。不同收入群体在知识方面没有差异。高收入组态度得分(78.7±8.4%)优于低收入组(70.9±11.8%)。高收入组实践评分(44.7±16.0%)优于中低收入组(31.3±14.5%)和28.6±15.0%)。孟加拉国高胆固醇血症型2型糖尿病患者的态度水平较好,但知识和实践得分不理想。教育程度和收入状况是糖尿病患者血脂异常的知识、态度和行为的主要决定因素。需要一项协调一致的政策来促进对健康生活方式的认识和态度,并将其付诸实践。DOI: http://dx.doi.org/10.3329/imcj.v5i2.10096 IMCJ 2011;5 (2): 37-41
{"title":"Knowledge, Attitude And Practice Of Hypercholesterolemic Type 2 Diabetic Subjects On Dyslipidemia","authors":"F. Saleh, S. Mumu, F. Afnan, L. Ali, H. Chaudhury, A. Akhter, K. Ahmed, Sanzida Akter","doi":"10.3329/IMCJ.V5I2.10096","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I2.10096","url":null,"abstract":"This study was undertaken to assess the knowledge, attitude and practice (KAP) of hypercholesterolemic type 2 diabetic subjects on dyslipidemia and to analyze the influence of some demographic and socioeconomic factors on the level of KAP.It was a descriptive cross-sectional survey. One hundred eleven newly diagnosed type 2 diabetic subjects (male 61%, female 39%, age 45±9 years, BMI 24±4.8 Kg/m 2 ) with hypercholesterolemia (fasting plasma total cholesterol >200 mg/dl) were selected from the out patient department of BIRDEM by purposive sampling method. Data were collected by a pre-designed, pretested, interviewer-administered questionnaire. Three categories were defined on the basis of the score obtained by each subject namely low, medium and high as follows: knowledge-score 60%; attitude-score 80%; and practice-score 70% respectively. The levels of knowledge were low in 42%, medium in 35% and high in 23% of the study subjects. The corresponding attitude levels were low in 1%, medium in 31% and high in 68%, and the levels of practice were low in 80%, medium in 14% and high in 6% of the subjects. The knowledge score was higher in secondary and graduate (53.4±8.9%, and 54.9±10.1%) groups compared to illiterate-primary group (48.9±9.9%). Practice score of illiterate-primary group (34.5±16.8%) was lower than secondary and graduate (43.1±13.9% and 46.7±18.1%) groups, but they did not differ on attitude. The various income groups did not differ on knowledge. Attitude score of high-income group (78.7±8.4%) was better than low-income group (70.9±11.8%). Practice score in high-income group (44.7±16.0%) was better than medium income and low-income groups (31.3±14.5% and 28.6±15.0%). Knowledge and practice score in Bangladeshi hypercholesterolemic type 2 diabetic subjects are not satisfactory although they have fairly good attitude levels. Education and income status are the major determinants of knowledge, attitude and practice regarding dyslipidemia in diabetes. A coordinated policy is required to promote knowledge and attitude on healthy lifestyle and to translate those into practice. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10096 IMCJ 2011; 5(2): 37-41","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124949089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
DISTRIBUTION OF PHENOTYPIC AND GENOTYPIC ABO AND RHESUS BLOOD GROUPS AMONG BANGLADESHI POPULATION 孟加拉国人群中abo血型和恒河血型的表型和基因型分布
Pub Date : 2012-03-12 DOI: 10.3329/IMCJ.V5I2.10101
T. Dipta, R. Iqbal, A. Hossain, Tahminur Rahman, S. Chowdhury
The present study is a retrospective analysis of allelic frequency of ABO and Rhesus (D) blood groups of donors attending the Deaprtment of Transfusion Medicine of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka. BIRDEM IS a 625 bed hospital, where patients and blood donors come from all parts of Bangladesh. A total of 1, 28,506 blood donors of both genders were included in the study over fourteen years from June 1995 to June 2009 for analysis. Blood group was determined by performing the both tube and slide method blood grouping method. The distribution of blood groups in our population was B>O>A>AB in Rh positive groups donors and O>B>A>AB among Rh negative donors. Blood group B was more common among the males (37.42%) while O was predominant among female donors (33.83 %). On the other hand, blood group O negative was predominant in both genders (36.88%). In this study, Hardy- Weinberg equilibrium law was used to calculate the allelic frequency for ABO/ Rh system. Homozygous allelic frequency for Rh negative population was only 0.0007. Although phenotypically B group was dominant and AB was rare in our population, but according to Hardy- Weinberg equilibrium law the estimated allelic frequency of A (0.3694) and O (0.3040) showed higher frequency than B type (0.2300) in Bangladeshi population in both homozygous and heterozygous state. So, with increasing population of Bangladesh, this changing trend in estimated blood group in ABO system may play an important role in our genetic pattern. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10101 IMCJ 2011; 5(2): 59-62
本研究回顾性分析了在达卡孟加拉国糖尿病、内分泌和代谢疾病研究与康复研究所(BIRDEM)输血医学系就诊的献血者ABO和恒河猴(D)血型的等位基因频率。BIRDEM是一家拥有625张床位的医院,病人和献血者来自孟加拉国各地。从1995年6月到2009年6月的14年间,共有128,506名男女献血者参与了这项研究。采用管式和玻片式两种方法进行血型测定。人群血型分布为Rh阳性供者B>O>A>AB, Rh阴性供者O>B>A>AB。男性以B型血多见(37.42%),女性以O型血多见(33.83%)。另一方面,男女均以O型阴性为主(36.88%)。本研究采用Hardy- Weinberg平衡定律计算ABO/ Rh系统的等位基因频率。Rh阴性群体纯合等位基因频率仅为0.0007。虽然在我国人群中B型为显性,AB型为罕见,但根据Hardy- Weinberg平衡定律,在孟加拉人群中纯合和杂合状态下,A型(0.3694)和O型(0.3040)的估计等位基因频率均高于B型(0.2300)。因此,随着孟加拉国人口的增加,ABO系统中估计血型的这种变化趋势可能在我们的遗传模式中发挥重要作用。DOI: http://dx.doi.org/10.3329/imcj.v5i2.10101 IMCJ 2011;5 (2): 59 - 62
{"title":"DISTRIBUTION OF PHENOTYPIC AND GENOTYPIC ABO AND RHESUS BLOOD GROUPS AMONG BANGLADESHI POPULATION","authors":"T. Dipta, R. Iqbal, A. Hossain, Tahminur Rahman, S. Chowdhury","doi":"10.3329/IMCJ.V5I2.10101","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I2.10101","url":null,"abstract":"The present study is a retrospective analysis of allelic frequency of ABO and Rhesus (D) blood groups of donors attending the Deaprtment of Transfusion Medicine of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka. BIRDEM IS a 625 bed hospital, where patients and blood donors come from all parts of Bangladesh. A total of 1, 28,506 blood donors of both genders were included in the study over fourteen years from June 1995 to June 2009 for analysis. Blood group was determined by performing the both tube and slide method blood grouping method. The distribution of blood groups in our population was B>O>A>AB in Rh positive groups donors and O>B>A>AB among Rh negative donors. Blood group B was more common among the males (37.42%) while O was predominant among female donors (33.83 %). On the other hand, blood group O negative was predominant in both genders (36.88%). In this study, Hardy- Weinberg equilibrium law was used to calculate the allelic frequency for ABO/ Rh system. Homozygous allelic frequency for Rh negative population was only 0.0007. Although phenotypically B group was dominant and AB was rare in our population, but according to Hardy- Weinberg equilibrium law the estimated allelic frequency of A (0.3694) and O (0.3040) showed higher frequency than B type (0.2300) in Bangladeshi population in both homozygous and heterozygous state. So, with increasing population of Bangladesh, this changing trend in estimated blood group in ABO system may play an important role in our genetic pattern. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10101 IMCJ 2011; 5(2): 59-62","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120865116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Sonographic Measurement Of Inferior Vena Cava Diameter A Noninvasive Tool To Detect Acute Blood Loss 超声测量下腔静脉内径——一种检测急性失血的无创工具
Pub Date : 2012-03-12 DOI: 10.3329/IMCJ.V5I2.10099
K. Das, S. A. Begum, S. Dey, M. Quddus, A. Mohiuddin
Detection and monitoring of blood loss in trauma patients can often be challenging. Change in the inferior vena cava diameter (IVCd) occurs due to alteration in circulating blood volume (CBV) and blood loss. Ultrasonographic measurement of IVCd provides a noninvasive real-time information of the CBV. The present study was designed to determine whether acute blood loss could be detected by sonographic measurement of the IVCd. A total of 50 volunteer blood donors aged 18 to 57 years were studied in the Department of Radiology and Imaging of Dhaka Medical College Hospital (DMCH) from July 2004 to June 2005. The inferior vena cava diameters, both during inspiration and expiration were measured by ultrasound examination immediately before and after donation of a single unit (450ml) of blood. During examination, the transducer was applied to the epigastrium parallel to the median line about 2 cm to the right of it for sagittal sections, and at a right angle to the median line about 3 cm below the xiphoid process for transverse sections. In sagittal sections, the inferior vena cava behind the liver were imaged during inspiration and expiration. The mean diameter of IVC during expiration before and after the blood donation was 17.5mm (±1.56mm) and 11.93mm (±1.48mm) respectively. Likewise, the mean diameter of IVC during inspiration before and after the blood donation was 12.96mm (±1.61mm) and 7.58mm (±1.29mm) respectively. The decrease in INV diameter following blood loss was significant (p< 0.01). Thus, the acute depletion of CBV could be detected by measuring the change of IVCd by sonography. Further study may be undertaken to determine the relationship of unit change of IVCd due to acute blood loss in case of trauma or other conditions. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10099 IMCJ 2011; 5(2): 51-53
检测和监测创伤患者的失血往往具有挑战性。下腔静脉直径(IVCd)的改变是由于循环血容量(CBV)和失血的改变而发生的。超声测量IVCd提供了CBV的无创实时信息。本研究旨在确定超声测量IVCd是否可以检测急性失血。2004年7月至2005年6月,在达卡医学院医院(DMCH)放射学和影像科对50名年龄在18至57岁之间的志愿献血者进行了研究。在单单位(450ml)献血前后立即进行超声检查,测量吸气和呼气时下腔静脉直径。检查时,矢状面将换能器置于与上腹部右侧中线平行约2cm的上腹部,横切面将换能器置于剑突下方约3cm的上腹部与中线成直角。在矢状面上,吸气和呼气时显示肝后下腔静脉。献血前后下腔静脉平均直径分别为17.5mm(±1.56mm)和11.93mm(±1.48mm)。同样,献血前后吸气时下腔静脉平均直径分别为12.96mm(±1.61mm)和7.58mm(±1.29mm)。出血后静脉内径明显减小(p< 0.01)。因此,超声可以通过测量IVCd的变化来检测CBV的急性耗竭。外伤或其他情况下急性失血与IVCd单位变化的关系有待进一步研究。DOI: http://dx.doi.org/10.3329/imcj.v5i2.10099 IMCJ 2011;5(2):。51号~ 53号
{"title":"Sonographic Measurement Of Inferior Vena Cava Diameter A Noninvasive Tool To Detect Acute Blood Loss","authors":"K. Das, S. A. Begum, S. Dey, M. Quddus, A. Mohiuddin","doi":"10.3329/IMCJ.V5I2.10099","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I2.10099","url":null,"abstract":"Detection and monitoring of blood loss in trauma patients can often be challenging. Change in the inferior vena cava diameter (IVCd) occurs due to alteration in circulating blood volume (CBV) and blood loss. Ultrasonographic measurement of IVCd provides a noninvasive real-time information of the CBV. The present study was designed to determine whether acute blood loss could be detected by sonographic measurement of the IVCd. A total of 50 volunteer blood donors aged 18 to 57 years were studied in the Department of Radiology and Imaging of Dhaka Medical College Hospital (DMCH) from July 2004 to June 2005. The inferior vena cava diameters, both during inspiration and expiration were measured by ultrasound examination immediately before and after donation of a single unit (450ml) of blood. During examination, the transducer was applied to the epigastrium parallel to the median line about 2 cm to the right of it for sagittal sections, and at a right angle to the median line about 3 cm below the xiphoid process for transverse sections. In sagittal sections, the inferior vena cava behind the liver were imaged during inspiration and expiration. The mean diameter of IVC during expiration before and after the blood donation was 17.5mm (±1.56mm) and 11.93mm (±1.48mm) respectively. Likewise, the mean diameter of IVC during inspiration before and after the blood donation was 12.96mm (±1.61mm) and 7.58mm (±1.29mm) respectively. The decrease in INV diameter following blood loss was significant (p< 0.01). Thus, the acute depletion of CBV could be detected by measuring the change of IVCd by sonography. Further study may be undertaken to determine the relationship of unit change of IVCd due to acute blood loss in case of trauma or other conditions. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10099 IMCJ 2011; 5(2): 51-53","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123566426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Growth Of Very Low Birth Weight Infants And Its Association With Feeding Regimens 极低出生体重儿的生长及其与喂养方式的关系
Pub Date : 2012-03-12 DOI: 10.3329/IMCJ.V5I2.10100
Mohammad Faizul Haque Khan, M. Chowdhury, M. Hoque, Mohammed Maruf-ul-Quaeder, Mahfuza Shirin, M. Hossain, Rumana Aziz
Clinical care of infants with very low birth weight (weighing<1500 gm at birth) in developing countries can be labour intensive and is often associated with a prolonged stay in hospital. Although several studies have shown the benefits of early discharge from the hospital for premature infants, it is still a common practice to delay discharge of these infants until they reach a weight of 2000 gm or more. The present study was undertaken to test the assumption that very low birth weight (VLBW) infants can attain optimum growth at home and to find its association with feeding regimens. This prospective observational study was conducted at Neonatal Out-patient Department, Dhaka Shishu Hospital over a period of 1 year from January 2010 to December 2010. A total of 92 very low birth weight neonates were enrolled during discahrge in the Neonatal Unit of Dhaka Shisu Hospital. Out of these 92 neonates 16 neonates expired while 7, 4 and 1 neonates dropped out in the first, second and third follow up respectively. The neonates after discharge were fed on three types of feeding regimens at home. The feeding regimens were expressed breast milk (EBM), EBM+ infant formula (mixed feeding) and infant formula only).The outcome variable was growth in terms of increase in weight, length and occiputo-frontal circumference (OFC). The other outcome measures were respiratory tract infection (RTI), diarrhoea and anaemia, visit to physician and readmission to hospital for the morbidities they encountered. The neonates were observed up to three consecutive follow-ups from their date of discharge. The median gestational age at birth was 31 weeks. Approximately 57% of the neonates were admitted within 72 hours of birth with median age at admission being 24 hours. Females were slightly higher (54.3%) than the males (45.7%). The mean weight, length and OFC at admission were 1208 gm 39.8 cm and 28.3 cm respectively. The study demonstrated a steady increase of weight, length and OFC of the infants up to a median age of 6 months with mixed and EBM feeding compared to infant formula group. Regarding RTI, diarhoea and anaemia the breast fed group suffered less frequently than the groups fed with infant formula and EBM+infant formula groups. The frequency of visits to physician and hospital admission were significantly lower in the EBM group than the other two groups. Higher frequency of breast feeding reduced the chance of infection and its severity. Infants discharged below1500 gm grew well with exclusive breast milk. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10100 IMCJ 2011; 5(2): 54-58
在发展中国家,极低出生体重(出生时体重<1500克)婴儿的临床护理可能是劳动密集型的,并且往往与长时间住院有关。虽然有几项研究表明早产婴儿早期出院的好处,但通常的做法仍然是将这些婴儿延迟出院,直到他们达到2000克或更多的体重。本研究旨在验证极低出生体重(VLBW)婴儿可以在家中获得最佳生长的假设,并发现其与喂养方案的关系。这项前瞻性观察研究于2010年1月至2010年12月在达卡Shishu医院新生儿门诊部进行,为期1年。达卡Shisu医院新生儿病房在出院期间共登记了92名出生体重极低的新生儿。92例新生儿中有16例死亡,7例、4例和1例在第一次、第二次和第三次随访中退出。出院后的新生儿在家中按三种喂养方案进行喂养。喂养方案为表达母乳(EBM)、EBM+婴儿配方奶粉(混合喂养)和纯婴儿配方奶粉。结果变量是体重、长度和枕额围(OFC)的增长。其他结果测量是呼吸道感染(RTI)、腹泻和贫血、看医生和因他们遇到的发病率再入院。这些新生儿从出院之日起连续随访三次。出生时的中位胎龄为31周。约57%的新生儿在出生后72小时内入院,入院时中位年龄为24小时。女性(54.3%)略高于男性(45.7%)。入院时平均体重1208克,体长39.8厘米,OFC 28.3厘米。研究表明,与婴儿配方奶粉组相比,混合喂养和EBM喂养的婴儿体重、身高和OFC在中位年龄6个月前稳步增加。在RTI、腹泻和贫血方面,母乳喂养组的发生率低于婴儿配方奶粉喂养组和EBM+婴儿配方奶粉喂养组。与其他两组相比,EBM组的就诊频率和住院次数明显较低。更高频率的母乳喂养减少了感染的机会及其严重程度。1500克以下的婴儿在纯母乳下生长良好。DOI: http://dx.doi.org/10.3329/imcj.v5i2.10100 IMCJ 2011;5 (2):
{"title":"Growth Of Very Low Birth Weight Infants And Its Association With Feeding Regimens","authors":"Mohammad Faizul Haque Khan, M. Chowdhury, M. Hoque, Mohammed Maruf-ul-Quaeder, Mahfuza Shirin, M. Hossain, Rumana Aziz","doi":"10.3329/IMCJ.V5I2.10100","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I2.10100","url":null,"abstract":"Clinical care of infants with very low birth weight (weighing<1500 gm at birth) in developing countries can be labour intensive and is often associated with a prolonged stay in hospital. Although several studies have shown the benefits of early discharge from the hospital for premature infants, it is still a common practice to delay discharge of these infants until they reach a weight of 2000 gm or more. The present study was undertaken to test the assumption that very low birth weight (VLBW) infants can attain optimum growth at home and to find its association with feeding regimens. This prospective observational study was conducted at Neonatal Out-patient Department, Dhaka Shishu Hospital over a period of 1 year from January 2010 to December 2010. A total of 92 very low birth weight neonates were enrolled during discahrge in the Neonatal Unit of Dhaka Shisu Hospital. Out of these 92 neonates 16 neonates expired while 7, 4 and 1 neonates dropped out in the first, second and third follow up respectively. The neonates after discharge were fed on three types of feeding regimens at home. The feeding regimens were expressed breast milk (EBM), EBM+ infant formula (mixed feeding) and infant formula only).The outcome variable was growth in terms of increase in weight, length and occiputo-frontal circumference (OFC). The other outcome measures were respiratory tract infection (RTI), diarrhoea and anaemia, visit to physician and readmission to hospital for the morbidities they encountered. The neonates were observed up to three consecutive follow-ups from their date of discharge. The median gestational age at birth was 31 weeks. Approximately 57% of the neonates were admitted within 72 hours of birth with median age at admission being 24 hours. Females were slightly higher (54.3%) than the males (45.7%). The mean weight, length and OFC at admission were 1208 gm 39.8 cm and 28.3 cm respectively. The study demonstrated a steady increase of weight, length and OFC of the infants up to a median age of 6 months with mixed and EBM feeding compared to infant formula group. Regarding RTI, diarhoea and anaemia the breast fed group suffered less frequently than the groups fed with infant formula and EBM+infant formula groups. The frequency of visits to physician and hospital admission were significantly lower in the EBM group than the other two groups. Higher frequency of breast feeding reduced the chance of infection and its severity. Infants discharged below1500 gm grew well with exclusive breast milk. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10100 IMCJ 2011; 5(2): 54-58","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133460392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AWARENESS OF HIV / AIDS AMONG THE GRASS-WIDOWS 草寡妇对艾滋病毒/艾滋病的认识
Pub Date : 2012-02-19 DOI: 10.3329/IMCJ.V5I1.9858
Tazreen Mona
The migrant workers in Bangladesh are at high risk of getting HIV infection due to factors like staying away from family for long periods which leave them vulnerable towards sexual relationship with commercial sex workers (CSW) and having sexual relationship with other men (MSM). This paper aimed to explore the level of awareness on HIV/AIDs among the women whose husbands stay apart from them for over a period of 6 months. For this cross sectional study, women attending public and private hospitals in Dhaka city were selected purposively. The participants were interviewed using a partially open-structured questionnaire. A total of 404 subjects were interviewed. Most of the respondents were housewives (85.7%). The higher education group had a high prevalence of awareness (>=HSC vs. SSC: 45.0% vs. 8.5%; p<0.001). The prevalence of awareness was significantly higher among the employed than the housewives (50% vs. 12.4%, p<0.001). Although the wives of the unskilled labor and the skilled employee were equal (25% vs. 25%), the wives of skilled employee had significantly higher awareness than the wives of the unskilled laborer (30.7 vs. 10.9%, p = 0.001). The study concludes that higher awareness level was significantly associated with higher education of the participants and higher education of the husband. Occupationally, housewives were found to have very low level of awareness compared with the employed group of participants. Again the wives of skilled employees had a significantly higher prevalence of awareness compared with the wives of unskilled laborer. Ibrahim Med. Coll. J. 2011; 5(1): 25-28 Key Words: HIV/AIDs; awareness; grass-widows. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9858
孟加拉国的移徙工人感染艾滋病毒的风险很高,因为他们长时间远离家人,容易与商业性工作者发生性关系,也容易与其他男性发生性关系。本文旨在探讨丈夫与她们分开超过6个月的妇女对艾滋病毒/艾滋病的认识水平。在这项横断面研究中,有目的地选择了在达卡市公立和私立医院就诊的妇女。参与者接受了部分开放式问卷调查。共采访了404名受试者。家庭主妇(85.7%)最多。高学历组有较高的知晓率(>=HSC vs. SSC: 45.0% vs. 8.5%;p < 0.001)。有工作的家庭主妇比有工作的家庭主妇有更高的意识(50% vs. 12.4%, p<0.001)。虽然非技术工人的妻子和熟练工人的妻子是平等的(25%对25%),但熟练工人的妻子的意识明显高于非技术工人的妻子(30.7%对10.9%,p = 0.001)。研究得出结论,较高的意识水平与参与者的高等教育程度和丈夫的高等教育程度显著相关。在职业方面,家庭主妇的意识水平与就业者相比非常低。同样,熟练工人的妻子比非熟练工人的妻子有更高的意识。易卜拉欣·迈德,上校。j . 2011;[关键词]艾滋病毒/艾滋病;意识;grass-widows。DOI: http://dx.doi.org/10.3329/imcj.v5i1.9858
{"title":"AWARENESS OF HIV / AIDS AMONG THE GRASS-WIDOWS","authors":"Tazreen Mona","doi":"10.3329/IMCJ.V5I1.9858","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I1.9858","url":null,"abstract":"The migrant workers in Bangladesh are at high risk of getting HIV infection due to factors like staying away from family for long periods which leave them vulnerable towards sexual relationship with commercial sex workers (CSW) and having sexual relationship with other men (MSM). This paper aimed to explore the level of awareness on HIV/AIDs among the women whose husbands stay apart from them for over a period of 6 months. For this cross sectional study, women attending public and private hospitals in Dhaka city were selected purposively. The participants were interviewed using a partially open-structured questionnaire. A total of 404 subjects were interviewed. Most of the respondents were housewives (85.7%). The higher education group had a high prevalence of awareness (>=HSC vs. SSC: 45.0% vs. 8.5%; p<0.001). The prevalence of awareness was significantly higher among the employed than the housewives (50% vs. 12.4%, p<0.001). Although the wives of the unskilled labor and the skilled employee were equal (25% vs. 25%), the wives of skilled employee had significantly higher awareness than the wives of the unskilled laborer (30.7 vs. 10.9%, p = 0.001). The study concludes that higher awareness level was significantly associated with higher education of the participants and higher education of the husband. Occupationally, housewives were found to have very low level of awareness compared with the employed group of participants. Again the wives of skilled employees had a significantly higher prevalence of awareness compared with the wives of unskilled laborer. Ibrahim Med. Coll. J. 2011; 5(1): 25-28 Key Words: HIV/AIDs; awareness; grass-widows. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9858","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127256676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Nigella sativa Linn (Ranunculaceae) ground seed extract on carrageenan induced inflammation in rats 黑马籽提取物对卡拉胶诱导大鼠炎症的影响
Pub Date : 2012-02-19 DOI: 10.3329/IMCJ.V5I1.9857
S. Parveen, S. C. Bachar, Z. A. Begum
Nigella sativa Linn (Family: Ranunculaceae) Bengali name “kalo jera” is used as spice in Bengali foods. Native to Western Asia, Turkey, Iraq and Egypt, the black seed oil has been valued for its health benefits for centuries. This plant has been used in traditional medicine for the treatment of stomach aches, asthma, bronchitis, coughs, fevers, tumour and as a tonic. The dried and grounded seed was extracted with ethanol and the extract was evaluated for anti-inflammatory activity in carrageenan induced rat paw edema model. The extracts were administered orally at the doses of 250 and 500 mg/kg body weight, and statistically significant ( p <0.05) anti-inflammatory effects were observed in a dose dependant manner. The extract showed 28.75% and 43.79% inhibition of inflammation at the doses of 250 and 500 mg/kg body weight after first hour of the carrageenan administration which was comparable to that of standard drugs aspirin 40.52% and hydrocortisone 47.71% respectively. The result of this study supported the traditional medicinal uses of this seed. Ibrahim Med. Coll. J. 2011; 5(1): 22-24 Key word: Nigella sativa; inflammation; carrageenan DOI: http://dx.doi.org/10.3329/imcj.v5i1.9857
黑黑的(科:毛茛科)孟加拉语名称“kalo jera”在孟加拉食品中用作香料。黑籽油原产于西亚、土耳其、伊拉克和埃及,几个世纪以来一直因其有益健康而受到重视。这种植物在传统医学中用于治疗胃痛、哮喘、支气管炎、咳嗽、发烧、肿瘤和补品。用乙醇提取干燥和磨碎的种子,并在卡拉胶诱导的大鼠足跖水肿模型中评价提取物的抗炎活性。给药剂量分别为250和500 mg/kg体重,抗炎作用呈剂量依赖性(p <0.05)。角叉菜胶给药1 h后,250 mg/kg和500 mg/kg剂量的提取物对炎症的抑制率分别为28.75%和43.79%,与标准药物阿司匹林(40.52%)和氢化可的松(47.71%)相当。这项研究的结果支持了这种种子的传统药用价值。易卜拉欣·迈德,上校。j . 2011;5(1): 22-24炎症;卡拉胶DOI: http://dx.doi.org/10.3329/imcj.v5i1.9857
{"title":"Effect of Nigella sativa Linn (Ranunculaceae) ground seed extract on carrageenan induced inflammation in rats","authors":"S. Parveen, S. C. Bachar, Z. A. Begum","doi":"10.3329/IMCJ.V5I1.9857","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I1.9857","url":null,"abstract":"Nigella sativa Linn (Family: Ranunculaceae) Bengali name “kalo jera” is used as spice in Bengali foods. Native to Western Asia, Turkey, Iraq and Egypt, the black seed oil has been valued for its health benefits for centuries. This plant has been used in traditional medicine for the treatment of stomach aches, asthma, bronchitis, coughs, fevers, tumour and as a tonic. The dried and grounded seed was extracted with ethanol and the extract was evaluated for anti-inflammatory activity in carrageenan induced rat paw edema model. The extracts were administered orally at the doses of 250 and 500 mg/kg body weight, and statistically significant ( p <0.05) anti-inflammatory effects were observed in a dose dependant manner. The extract showed 28.75% and 43.79% inhibition of inflammation at the doses of 250 and 500 mg/kg body weight after first hour of the carrageenan administration which was comparable to that of standard drugs aspirin 40.52% and hydrocortisone 47.71% respectively. The result of this study supported the traditional medicinal uses of this seed. Ibrahim Med. Coll. J. 2011; 5(1): 22-24 Key word: Nigella sativa; inflammation; carrageenan DOI: http://dx.doi.org/10.3329/imcj.v5i1.9857","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130694944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Bee envenomation induced acute renal failure in an 8 year old child 蜜蜂中毒致1例8岁儿童急性肾衰竭
Pub Date : 2012-02-19 DOI: 10.3329/IMCJ.V5I1.9872
F. Islam, Syed Dawood Md Taimur, C. Kabir
Massive envenomations by bees are capable of causing multiorgan dysfunction as a result of direct toxic effects of the large venom load received. Although all varieties of honey bee have the potential for these attacks, the Africanized honey bee ( Apis mellifera scutellata ) is the most commonly implicated subspecies. In the United States, the Africanized strain is found primarily in the southwestern states and is known for its highly defensive behavior if disturbed. Mechanisms behind the multiorgan dysfunction produced by these mass envenomations are not clearly understood. We present a case of an 8-year-old boy who was stung by multiple bees and developed progressive upper-body swelling and systemic manifestations of mass envenomation including rhabdomyolysis, renal insufficiency, and a transient transaminase elevation. Ibrahim Med. Coll. J. 2011; 5(1): 34-36 Key Words: environmental risk; renal failure; rhabdomyolysis; bee envenomation. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9872
由于大量的毒液负荷的直接毒性作用,蜜蜂的大量中毒能够引起多器官功能障碍。尽管所有种类的蜜蜂都有这种攻击的可能,但非洲化的蜜蜂(Apis mellifera scutellata)是最常见的牵连亚种。在美国,非洲化菌株主要在西南部各州发现,并以其受到干扰时的高度防御行为而闻名。这些大规模中毒所产生的多器官功能障碍背后的机制尚不清楚。我们报告了一个8岁的男孩,他被多只蜜蜂蜇伤,出现进行性上半身肿胀和全身大面积中毒症状,包括横纹肌溶解、肾功能不全和短暂的转氨酶升高。易卜拉欣·迈德,上校。j . 2011;[关键词]环境风险;肾功能衰竭;横纹肌溶解;蜜蜂表面变质。DOI: http://dx.doi.org/10.3329/imcj.v5i1.9872
{"title":"Bee envenomation induced acute renal failure in an 8 year old child","authors":"F. Islam, Syed Dawood Md Taimur, C. Kabir","doi":"10.3329/IMCJ.V5I1.9872","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I1.9872","url":null,"abstract":"Massive envenomations by bees are capable of causing multiorgan dysfunction as a result of direct toxic effects of the large venom load received. Although all varieties of honey bee have the potential for these attacks, the Africanized honey bee ( Apis mellifera scutellata ) is the most commonly implicated subspecies. In the United States, the Africanized strain is found primarily in the southwestern states and is known for its highly defensive behavior if disturbed. Mechanisms behind the multiorgan dysfunction produced by these mass envenomations are not clearly understood. We present a case of an 8-year-old boy who was stung by multiple bees and developed progressive upper-body swelling and systemic manifestations of mass envenomation including rhabdomyolysis, renal insufficiency, and a transient transaminase elevation. Ibrahim Med. Coll. J. 2011; 5(1): 34-36 Key Words: environmental risk; renal failure; rhabdomyolysis; bee envenomation. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9872","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121446306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Diagnostic significance of pleural fluid adenosine deaminase activity in tuberculous pleurisy 胸膜液腺苷脱氨酶活性对结核性胸膜炎的诊断意义
Pub Date : 2012-02-19 DOI: 10.3329/IMCJ.V5I1.9852
Sharmeen Ahmed, Reaz Fatema, A. Saleh, M. Sattar, R. Miah
Diagnosis of tuberculous pleural effusion (TPE) is difficult because of its non-specific clinical presentation and insufficient efficiency of conventional diagnostic methods. The study was carried out to evaluate the utility of adenosine deaminase (ADA) activity in pleural fluid for the diagnosis of TPE. ADA activity was measured in pleural fluid of 103 pleural effusion patients by colorimetric method using a commercial ADA assay kit. The diagnosis of TPE was made from pleural fluid examinations (including cytology, biochemistry, and bacteriology) and pleural biopsy. Patient with negative result of this methods were diagnosed by response of empirical treatment. Out of 130 cases, 62 (61.1%) had TPE and the remaining 41 (39.8%) had pleural effusion due to non tuberculous diseases. There was statistically significant difference (p < 0.001) between the mean of pleural fluid ADA levels (70.82±22.54 U/L) in TPE group and (30.07±22.93 U/L) in non-TPE group. Of 62 TPE cases, microscopy for AFB and culture for M.tuberculosis in pleural fluid revealed positivity in 9.6% and 22.5% cases respectively, and biopsy of pleura showed typical epithelioid granuloma in only 43.5% cases. The cut-off value of ADA for diagnosing TPE was 40 U/L using a ROC curve, with a sensitivity of 94% and specificity of 88%. Positive and negative predictive value of ADA assay were 92% and 90% respectively. The overall test accuracy was 90%. Pleural fluid ADA assay is therefore a simple, rapid, highly sensitive and specific adjunct test for diagnosis of TPE. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9852 Ibrahim Med. Coll. J. 2011; 5(1): 1-5 Keywords: Pleural fluid; adenosine deaminase; tuberculous pleural effusion
结核性胸腔积液(TPE)临床表现不明确,常规诊断方法效率不足,是诊断的难点。本研究旨在评估胸膜液中腺苷脱氨酶(ADA)活性在TPE诊断中的应用价值。采用商用ADA检测试剂盒,采用比色法测定103例胸腔积液患者胸液中ADA活性。TPE的诊断是通过胸膜液检查(包括细胞学、生物化学和细菌学)和胸膜活检。对方法阴性的患者,根据经验治疗反应进行诊断。130例中,62例(61.1%)有TPE,其余41例(39.8%)有非结核性疾病引起的胸腔积液。TPE组胸膜液ADA平均值(70.82±22.54 U/L)与非TPE组(30.07±22.93 U/L)比较,差异有统计学意义(p < 0.001)。62例TPE病例中,AFB镜检和胸膜液结核分枝杆菌培养分别为9.6%和22.5%,胸膜活检显示典型上皮样肉芽肿的病例仅为43.5%。采用ROC曲线,ADA诊断TPE的临界值为40 U/L,灵敏度为94%,特异性为88%。ADA检测阳性预测值为92%,阴性预测值为90%。总体测试准确率为90%。因此,胸膜液ADA检测是一种简单、快速、高灵敏度和特异性的TPE诊断辅助试验。DOI: http://dx.doi.org/10.3329/imcj.v5i1.9852 Ibrahim Med. col。j . 2011;关键词:胸腔积液;腺苷脱氨酶;结核性胸腔积液
{"title":"Diagnostic significance of pleural fluid adenosine deaminase activity in tuberculous pleurisy","authors":"Sharmeen Ahmed, Reaz Fatema, A. Saleh, M. Sattar, R. Miah","doi":"10.3329/IMCJ.V5I1.9852","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I1.9852","url":null,"abstract":"Diagnosis of tuberculous pleural effusion (TPE) is difficult because of its non-specific clinical presentation and insufficient efficiency of conventional diagnostic methods. The study was carried out to evaluate the utility of adenosine deaminase (ADA) activity in pleural fluid for the diagnosis of TPE. ADA activity was measured in pleural fluid of 103 pleural effusion patients by colorimetric method using a commercial ADA assay kit. The diagnosis of TPE was made from pleural fluid examinations (including cytology, biochemistry, and bacteriology) and pleural biopsy. Patient with negative result of this methods were diagnosed by response of empirical treatment. Out of 130 cases, 62 (61.1%) had TPE and the remaining 41 (39.8%) had pleural effusion due to non tuberculous diseases. There was statistically significant difference (p < 0.001) between the mean of pleural fluid ADA levels (70.82±22.54 U/L) in TPE group and (30.07±22.93 U/L) in non-TPE group. Of 62 TPE cases, microscopy for AFB and culture for M.tuberculosis in pleural fluid revealed positivity in 9.6% and 22.5% cases respectively, and biopsy of pleura showed typical epithelioid granuloma in only 43.5% cases. The cut-off value of ADA for diagnosing TPE was 40 U/L using a ROC curve, with a sensitivity of 94% and specificity of 88%. Positive and negative predictive value of ADA assay were 92% and 90% respectively. The overall test accuracy was 90%. Pleural fluid ADA assay is therefore a simple, rapid, highly sensitive and specific adjunct test for diagnosis of TPE. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9852 Ibrahim Med. Coll. J. 2011; 5(1): 1-5 Keywords: Pleural fluid; adenosine deaminase; tuberculous pleural effusion","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127815869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Body mass abdominal index: a new index for a diposity among pre-school children 体重腹部指数:学龄前儿童肥胖的新指标
Pub Date : 2012-02-19 DOI: 10.3329/IMCJ.V5I1.9854
Subal Das, K. Bose
The new index Body Mass Abdominal Index (BMAI) has been derived by combining two separate indices – weight for height and waist for height ratios. Our study investigated the relationship of common indicators of abdominal adiposity – waist circumference (WC), waist-hip ratio (WHR), waist-height ratio (WHTR), conicity index (CI) and newly proposed body mass abdominal index (BMAI) with body mass index (BMI) among 347 pre-school children of Purulia District, India. Results showed that significant correlations were observed for all adiposity measures except WHR. A noteworthy point was that the correlations were strongest (p < 0.01) with BMAI (boys: r = 0.863, girls: r = 0.863). The correlations of BMAI with BMI were similar in both sexes. In conclusion, our results indicate that the new index BMAI has a distinct advantage as it relates much strongly with overall adiposity (BMI) than the other commonly used indicators of adiposity. Ibrahim Med. Coll. J. 2011; 5(1): 9-12 Key Words: Pre-school children; body mass index; body mass abdominal index; India. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9854
新的身体质量腹部指数(BMAI)是由两个独立的指数——身高的体重和身高的腰围比——结合而成的。本研究调查了印度Purulia地区347名学龄前儿童腹部肥胖的常见指标腰围(WC)、腰臀比(WHR)、腰高比(WHTR)、圆度指数(CI)和新提出的体重腹部指数(BMAI)与体重指数(BMI)的关系。结果显示,除腰宽比外,所有肥胖指标均存在显著相关性。值得注意的是,与BMAI的相关性最强(p < 0.01)(男孩:r = 0.863,女孩:r = 0.863)。BMAI与BMI的相关性在两性中相似。总之,我们的研究结果表明,与其他常用的肥胖指标相比,新的BMI指数具有明显的优势,因为它与整体肥胖(BMI)的相关性更强。易卜拉欣·迈德,上校。j . 2011;[关键词]学龄前儿童;身体质量指数;体重腹部指数;印度。DOI: http://dx.doi.org/10.3329/imcj.v5i1.9854
{"title":"Body mass abdominal index: a new index for a diposity among pre-school children","authors":"Subal Das, K. Bose","doi":"10.3329/IMCJ.V5I1.9854","DOIUrl":"https://doi.org/10.3329/IMCJ.V5I1.9854","url":null,"abstract":"The new index Body Mass Abdominal Index (BMAI) has been derived by combining two separate indices – weight for height and waist for height ratios. Our study investigated the relationship of common indicators of abdominal adiposity – waist circumference (WC), waist-hip ratio (WHR), waist-height ratio (WHTR), conicity index (CI) and newly proposed body mass abdominal index (BMAI) with body mass index (BMI) among 347 pre-school children of Purulia District, India. Results showed that significant correlations were observed for all adiposity measures except WHR. A noteworthy point was that the correlations were strongest (p < 0.01) with BMAI (boys: r = 0.863, girls: r = 0.863). The correlations of BMAI with BMI were similar in both sexes. In conclusion, our results indicate that the new index BMAI has a distinct advantage as it relates much strongly with overall adiposity (BMI) than the other commonly used indicators of adiposity. Ibrahim Med. Coll. J. 2011; 5(1): 9-12 Key Words: Pre-school children; body mass index; body mass abdominal index; India. DOI: http://dx.doi.org/10.3329/imcj.v5i1.9854","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122074510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Ibrahim Medical College Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1