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The Effect of Ageratum conyzoides L on Hepatocellular Carcinoma Rats Induced by DMBA based on In Vivo-In Silico Study 荆刺草对DMBA诱导大鼠肝癌的体内硅片研究
Heni Ratnasari, A. Rahma, Rifki Febriansah
Liver cancer is the second most common cause of cancer deaths worldwide. Treatment that has been carried out was chemotherapy which has many disadvantages. Bandotan Herb (Ageratum conyzoides L.) containing flavonoid compounds was used as chemopreventive agents. This research was experimental study using molecular docking test of nobiletin compounds against VEGF, COX-2 and C-Myc compared to 5Fluorouracil. Carcinogenic test required 20 mice tails to be divided into 5 feeding groups. Induction was conducted on a peroral using CMC-Na 0.5% 1 ml/200 gram, DMBA 20 mg/kg BW and BHCF at a dose of 750 mg/kg BW and 1500 mg/kg BW. DMBA was injected 2 times a week for 5 weeks. Histological observation was carried out using Immunohistochemistry and Haematoxylin-Eosin. TLC stated that BHCF contained flavonoid as a secondary metabolites. Molecular docking proved that nobiletin was better in inhibiting the expression of VEGF with an affinity value -7.6 kcal/mol. Induction of DMBA caused moderate over-expression of VEGF against liver tissue. Histologically, the introduction of BHCF at a dose of 1500 mg/kg BW provides better improvement degrees of histology than 750 mg/kg BW. The presence of flavonoid can be used as chemopreventive agents for liver cancer based on in silico and in vivo assay. Keywords—Ageratum comyzoides L., DMBA, hepatocellular carcinoma, in silico, in vivo
肝癌是全球癌症死亡的第二大常见原因。目前的治疗方法是化疗,但有很多缺点。以含黄酮类化合物的板多坦为化学预防剂。本研究是通过分子对接试验,与5氟尿嘧啶比较诺毕尔素化合物对VEGF、COX-2和C-Myc的抑制作用。致癌性试验将20只小鼠尾巴分为5个喂养组。以CMC-Na 0.5% 1 ml/200 g、DMBA 20 mg/kg BW和BHCF分别为750 mg/kg BW和1500 mg/kg BW对小鼠进行诱导。DMBA每周注射2次,连续5周。采用免疫组织化学和红木精-伊红进行组织学观察。薄层色谱显示BHCF中含有黄酮类化合物作为次生代谢产物。分子对接证实,诺比列素对VEGF的抑制作用较好,亲和值为-7.6 kcal/mol。诱导DMBA引起VEGF对肝组织的中度过度表达。组织学上,引入1500 mg/kg BW的BHCF比750 mg/kg BW的BHCF改善组织学程度更好。体外和体内实验结果表明,黄酮类化合物的存在可作为肝癌的化学预防药物。关键词:菊苣,DMBA,肝细胞癌,硅,体内
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引用次数: 0
The Impact of Community-based Health Education to Improve Quality of Nursing Services for People with Hypertension : A Literature Review 以社区为基础的健康教育对提高高血压患者护理服务质量的影响:文献综述
S. Nasela, Roni Latumenasse, C. Tatisina, Neti Juniarti, Mamat Lukman
Background: Essential hypertension is the most popular catastrophic case in Indonesia referred from primary health services to hospitals. High number of morbidity and mortality caused by hypertension increases financial burden of a state for catastrophic diseases. The current effort of our government to prevent and control hypertension is by health promotion through confirmation, information, and education. However, the facts that hypertension prevention keeps on developing making it a continuous global challenge for the professionals of health services. This is the reason why it's important to investigate interventions that could increase control the blood pressure. The aim of this systematic review is to gain the best literatures about health education on community-based hypertension prevention that has potential strength to regenerate clinical practice recommendations to improve preventive and promotive efforts for hypertension. Method of this literature review was using systematic searching of electronic databases from Google and Pubmed by following keywords: hypertension intervention strategies + journal, community based hypertension control programs that work + journal, hypertension AND community based health education, hypertension AND community-based nutrition DASH, hypertension AND community based control programs. Inclusion criteria of the study focused on community-based education interventions for hypertension and have completed explanation about it while exclusion criteria of the study was all articles that younger than the last 10 years. 13 articles based on the above criteria were chosen to proceed. Results of the study show that all researches were done in developed countries and most of the articles were using quantitative methods. Community-based health education for people with hypertension is an effort to help hypertension control programs. There are four health interventions related to community-based hypertension education program which are mass media campaign to reduce salt consumption, workshop programs through social volunteering or health activists, hypertension group education about DASH and lifestyle then comprehensive hypertension prevention and promotive programs. Community-based health education approaches through these interventions could be used to control the uncontrollable hypertension in the community. Multicomponent and multilevel cooperation as well as financially effective efforts to prevent, detect and manage hypertension could be gained by implementing all of these interventions.
背景:原发性高血压是印度尼西亚从初级卫生服务转诊到医院的最常见的灾难性病例。高血压引起的高发病率和死亡率增加了国家对灾难性疾病的经济负担。目前我国政府预防和控制高血压的努力是通过确认、信息和教育来促进健康。然而,高血压预防不断发展的事实使其成为卫生服务专业人员持续面临的全球性挑战。这就是为什么研究可以提高血压控制的干预措施很重要的原因。本系统综述的目的是获得以社区为基础的高血压预防健康教育的最佳文献,这些文献具有潜在的力量,可以再生临床实践建议,以改善高血压的预防和促进工作。文献综述方法:系统检索Google和Pubmed电子数据库,关键词:高血压干预策略+期刊,有效的社区高血压控制项目+期刊,高血压与社区健康教育,高血压与社区营养DASH,高血压与社区控制项目。本研究的纳入标准以社区为基础的高血压教育干预为重点,并对其进行了完整的解释,而本研究的排除标准为所有年龄小于10年的文章。根据上述标准选择了13篇文章进行研究。研究结果表明,所有的研究都是在发达国家进行的,并且大多数文章都使用了定量方法。以社区为基础的高血压患者健康教育有助于高血压控制项目。有四种健康干预措施与社区高血压教育项目有关即减少盐摄入量的大众媒体活动,通过社会志愿者或健康活动家开展的研讨会项目,高血压群体关于DASH和生活方式的教育以及高血压综合预防和促进项目。通过这些干预措施,以社区为基础的健康教育方法可用于控制社区的不可控高血压。通过实施所有这些干预措施,可以在预防、发现和管理高血压方面获得多部门和多层次的合作以及财政上的有效努力。
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引用次数: 1
Psychometric Testing of Instrument for Assessment of Nursing Students Professional Behavior in Indonesia 印尼护生专业行为测评工具的心理测量测试
Wulan Noviani, C. Chan, Tang Li Yoong
Professional behavior is a crucial aspect of nursing career success as professional nurses. Nursing education plays an essential role to educate the nursing student to manage the complex demand in health care environment accordingly. However, the instrument to measure professional behavior among nursing student remains scarce. The aim of research are to adapt and validate the Nursing Students Professional Behavior Scale (NSPBS) and measure professional behavior among Indonesian nursing students. The original instrument (27 items) was translated using the translation guideline by the World Health Organization (WHO) (2018). The total sample was 364 nursing students from Bachelor-level nursing school at the private university in Yogyakarta (Indonesia). The inclusion criteria were the students already been to clinical practice in the hospital. The data collected from August to September 2018. A Confirmatory Factor Analysis (CFA) using Partial Least Square (PLS)-Structural Equation Modelling (SEM) was conducted to evaluate the validity and reliability. The finding was fitted for the three-dimensions which were included in healthcare practice, activity practice, and reporting. The face validity and content validity was evaluated by six experts. The CFA showed the excellent result with factor-loadings varying from 0.70 to 0.96 for the constructs. While the composite reliability (CR) for all latent constructs ranged from 0.90 to 0.96, which means that the internal consistency reliability was high. The Indonesian version of NSPBS remained with 27 items and was tested to be a valid and reliable tool to measure the professional behavior of nursing students. The instrument will be useful for nurse educators to monitor the development of student nurses’ professionalism in clinical practice. Keywords—Assessment, nursing student, professional behavior, validation
作为专业护士,职业行为是护理事业成功的一个重要方面。护理教育对培养护生应对医疗环境中复杂需求的能力起着至关重要的作用。然而,衡量护生职业行为的工具仍然稀缺。研究的目的是适应和验证护理学生专业行为量表(NSPBS),并测量印尼护理学生的专业行为。原文书(27个项目)是根据世界卫生组织(世卫组织)的翻译指南(2018年)翻译的。总样本为364名来自日惹私立大学护理学院本科水平的护理学生(印度尼西亚)。入选标准为已到医院实习的学生。数据收集于2018年8月至9月。采用偏最小二乘(PLS)-结构方程模型(SEM)进行验证性因子分析(CFA)来评估效度和信度。这一发现适用于医疗保健实践、活动实践和报告的三个维度。由6位专家对问卷的表面效度和内容效度进行评估。CFA显示了良好的结果,因子负荷从0.70到0.96不等。各潜在构念的复合信度(CR)在0.90 ~ 0.96之间,具有较高的内部一致性信度。印尼语版的NSPBS保留了27个条目,被证明是衡量护生职业行为的有效和可靠的工具。该仪器将有助于护理教育者在临床实践中监测学生护士专业精神的发展。关键词:评估;护生;职业行为
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引用次数: 0
The Effectiveness of The Use of Cervical Cancer Prevention Guideline Book on Women Participation in Visual Inspection with Acetic acid (VIA) 妇女参与醋酸目视检查宫颈癌预防指南(VIA)的使用效果
A. Nisak, Atun Wigati, Z. Fanani, N. Cholifah
Cervical cancer is the second leading cause of death for women in the world after breast cancer. It is estimated that every 40-45 new cases occur and around 20-25 people die due to cervical cancer. In Kudus , the coverage of early detection of cervical cancer by the VIA method is only 2% of the number of women aged 30-50 years. This study aims to determine the effectiveness of health promotion and guidebook on the early detection of cervical cancer as an effort to increase the participation in women's VIA examination. This study was quasiexperimental with the design of the pretest posttest non equvialent control, The samples as many as 66 respondents were divided into two groups selected taken using consecutive sampling technique. Later on, the data were analyzed using McNemar and Chi Square tests. The results showed McNemar test results in the intervention group found there was an increase in knowledge and participation in the VIA examination compared to the control group. Obtained differences between the intervention group and the control group using the Chi Square test with the p value of 0.003. Providing health promotion and guidebooks for early detection of cervical cancer are very effective in increasing the knowledge and women participation of VIA examinations in Mejobo Subdistrict, Kudus Regency. Keywords—Guideline book, VIA Participation
宫颈癌是世界上仅次于乳腺癌的第二大妇女死亡原因。据估计,每40至45个新病例和约20至25人死于子宫颈癌。在库德斯,通过VIA方法对宫颈癌进行早期检测的覆盖率仅占30-50岁妇女人数的2%。这项研究的目的是确定健康促进和宫颈癌早期发现指南的有效性,以增加妇女对宫颈检查的参与。本研究采用准实验设计,采用前测后测非等效对照设计,采用连续抽样方法,将66名被试分为两组。随后,使用McNemar和卡方检验对数据进行分析。结果显示,干预组的McNemar测试结果显示,与对照组相比,干预组的知识和参与VIA考试的程度有所增加。采用卡方检验获得干预组与对照组的差异,p值为0.003。在库德斯县Mejobo街道,提供促进健康和早期发现宫颈癌的指南非常有效地提高了妇女对VIA检查的认识和参与程度。关键词:指南书;VIA参与
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引用次数: 1
Distribution of Dengue Hemorrhagic Fever (DHF) in Regards to Age and Sex in Sleman, Yogyakarta, Indonesia 登革出血热(DHF)在印度尼西亚日惹Sleman的年龄和性别分布
T. Kesetyaningsih
Dengue Hemorrhagic Fever (DHF) is a disease that has a rapid geographical spread and the number of occurrences is increasing. The disease is transmitted through the bite of Aedes aegypti or Aedes albopictus which sucks human blood during the day, so that the tramission might be related to human activities. In this sense, human activities are related to age and sex. This study aims to analyze descriptively the incidence of dengue fever based on age and sex. Secondary data in the form of data on DHF patients, including their age and sex, in the period of 2008 to 2013 were obtained from the Health Office of Sleman Regency, Yogyakarta, Indonesia. The results show: (1) the aspect of age: the number of occurrences in toddlers and children 5 to 14 years old ranged from 23.39% to 40.20% (35.68%), and the number of occurrences in patients ≥ 15 years old (adults) ranged from 47.90% to 66.13 % (51.39%); (2) the aspect of sex: it appears that the occurrences in male patients numbering as many as 770 (52.13%) were slightly higher than for females, numbering 707 (47.87%). It is concluded that the incidence of DHF in the Sleman Regency in the period of 2008 to 2013 is higher in adults and slightly higher in males.
登革出血热(DHF)是一种地理传播迅速的疾病,发病数量正在增加。该病是通过白天吸血的埃及伊蚊或白纹伊蚊叮咬传播的,因此传播可能与人类活动有关。从这个意义上说,人类的活动与年龄和性别有关。本研究的目的是描述性分析登革热的发病率基于年龄和性别。次要数据是2008年至2013年期间登革出血热患者的数据形式,包括其年龄和性别,这些数据来自印度尼西亚日惹Sleman Regency卫生办公室。结果表明:(1)年龄方面:幼儿和5 ~ 14岁儿童发病比例为23.39% ~ 40.20%(35.68%),≥15岁(成人)发病比例为47.90% ~ 66.13% (51.39%);(2)性别方面:男性患者的发病率为770例(52.13%),略高于女性患者的707例(47.87%)。综上所述,2008 - 2013年Sleman县DHF发病率成人较高,男性略高。
{"title":"Distribution of Dengue Hemorrhagic Fever (DHF) in Regards to Age and Sex in Sleman, Yogyakarta, Indonesia","authors":"T. Kesetyaningsih","doi":"10.2991/icosihsn-19.2019.3","DOIUrl":"https://doi.org/10.2991/icosihsn-19.2019.3","url":null,"abstract":"Dengue Hemorrhagic Fever (DHF) is a disease that has a rapid geographical spread and the number of occurrences is increasing. The disease is transmitted through the bite of Aedes aegypti or Aedes albopictus which sucks human blood during the day, so that the tramission might be related to human activities. In this sense, human activities are related to age and sex. This study aims to analyze descriptively the incidence of dengue fever based on age and sex. Secondary data in the form of data on DHF patients, including their age and sex, in the period of 2008 to 2013 were obtained from the Health Office of Sleman Regency, Yogyakarta, Indonesia. The results show: (1) the aspect of age: the number of occurrences in toddlers and children 5 to 14 years old ranged from 23.39% to 40.20% (35.68%), and the number of occurrences in patients ≥ 15 years old (adults) ranged from 47.90% to 66.13 % (51.39%); (2) the aspect of sex: it appears that the occurrences in male patients numbering as many as 770 (52.13%) were slightly higher than for females, numbering 707 (47.87%). It is concluded that the incidence of DHF in the Sleman Regency in the period of 2008 to 2013 is higher in adults and slightly higher in males.","PeriodicalId":227928,"journal":{"name":"Proceedings of the Third International Conference on Sustainable Innovation 2019 – Health Science and Nursing (IcoSIHSN 2019)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130792370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Eating And Drinking Habits Of Children At Kudus, Central Java,Indonesia 印度尼西亚中爪哇库德斯儿童的饮食习惯
I. Tristanti, Nasriyah, U. Kulsum, Islami
97.7% of children in Indonesia evidently consume less vegetables and fruits but eat more snack and instant drinks. Some of those snacks sometimes contain microbes, additives and harmful substances such as formalin, borax, artificial coloring, flavor enhancer, artificial sweeteners which lead to several illness like typhoid (2.7%), diarrhea (4.9%), hepatitis (1.9%), etc. This study aims to describe the eating and drinking habits of children at Kudus. This study was qualitative research with a phenomenological method. This study was conducted from July to September 2018 in Kudus in which it involved 12 participants. The sampling technique used was purposive sampling. In-depth interview and triangulation were done to collect the data. The result of this study stated that not all children were accustomed to having breakfast and they did not carry packed lunch from home. Moreover, schools did not have healthy canteens and the students were not used to washing hands cleanly appropriately. In fact, the children were not used to eat eating vegetables and fruit everyday and at school they brought pocket money to buy snacks and beverages containing lots of sweeteners, artificial coloring, preservatives, borax, and flavor enhancer in which some snacks were eaten using unhealthy sauces and spices. Teachers told the students not to buy unhealthy snacks and beverages, but they kept doing that secretly. Conclusion: the children habits in consuming unhealthy snacks and beverages must be immediately eradicated because it has the potential cause to nutritional disorders and health problems such as malnutrition, obesity and typhoid, sore throat, diarrhea etc. Keywords— the children’s habit, consume, snacks,
印尼97.7%的儿童明显少吃蔬菜和水果,多吃零食和速溶饮料。其中一些零食有时含有微生物、添加剂和有害物质,如福尔马林、硼砂、人工色素、增味剂、人工甜味剂等,可导致伤寒(2.7%)、腹泻(4.9%)、肝炎(1.9%)等疾病。本研究旨在描述库德斯儿童的饮食习惯。本研究采用现象学方法进行定性研究。这项研究于2018年7月至9月在库德斯进行,共有12名参与者。使用的抽样技术是有目的的抽样。通过深度访谈和三角测量来收集数据。这项研究的结果表明,并不是所有的孩子都习惯吃早餐,他们也没有从家里带午饭。此外,学校没有健康的食堂,学生不习惯正确洗手。事实上,孩子们不习惯每天吃蔬菜和水果,在学校他们带零花钱去买含有大量甜味剂、人工色素、防腐剂、硼砂和增味剂的零食和饮料,其中一些零食使用了不健康的酱汁和香料。老师告诉学生们不要买不健康的零食和饮料,但他们一直在偷偷地这样做。结论:儿童食用不健康零食和饮料的习惯有可能导致营养失调和健康问题,如营养不良、肥胖和伤寒、喉咙痛、腹泻等,必须立即根除。关键词:儿童习惯;消费;零食;
{"title":"The Eating And Drinking Habits Of Children At Kudus, Central Java,Indonesia","authors":"I. Tristanti, Nasriyah, U. Kulsum, Islami","doi":"10.2991/icosihsn-19.2019.21","DOIUrl":"https://doi.org/10.2991/icosihsn-19.2019.21","url":null,"abstract":"97.7% of children in Indonesia evidently consume less vegetables and fruits but eat more snack and instant drinks. Some of those snacks sometimes contain microbes, additives and harmful substances such as formalin, borax, artificial coloring, flavor enhancer, artificial sweeteners which lead to several illness like typhoid (2.7%), diarrhea (4.9%), hepatitis (1.9%), etc. This study aims to describe the eating and drinking habits of children at Kudus. This study was qualitative research with a phenomenological method. This study was conducted from July to September 2018 in Kudus in which it involved 12 participants. The sampling technique used was purposive sampling. In-depth interview and triangulation were done to collect the data. The result of this study stated that not all children were accustomed to having breakfast and they did not carry packed lunch from home. Moreover, schools did not have healthy canteens and the students were not used to washing hands cleanly appropriately. In fact, the children were not used to eat eating vegetables and fruit everyday and at school they brought pocket money to buy snacks and beverages containing lots of sweeteners, artificial coloring, preservatives, borax, and flavor enhancer in which some snacks were eaten using unhealthy sauces and spices. Teachers told the students not to buy unhealthy snacks and beverages, but they kept doing that secretly. Conclusion: the children habits in consuming unhealthy snacks and beverages must be immediately eradicated because it has the potential cause to nutritional disorders and health problems such as malnutrition, obesity and typhoid, sore throat, diarrhea etc. Keywords— the children’s habit, consume, snacks,","PeriodicalId":227928,"journal":{"name":"Proceedings of the Third International Conference on Sustainable Innovation 2019 – Health Science and Nursing (IcoSIHSN 2019)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115676647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Javanese Women’s Perception of Husband’s Support in Women Reproductive Health 爪哇妇女对丈夫支持妇女生殖健康的看法
Yusi Riwayatul Afsah, Yuni Astuti, S. Azizah, Bayu Muflihin
The husband’s involvement in reproductive health is a complex process of social and behavioral change. The role of men in women’s health I Indonesia felt to be very low for various reasons that have taken root in Indonesian society which tends to be patriarchal, in Javanese particularly. This descriptive study aimed to describe the women’s perceptions towards husband’s support in making decisions related to women’s reproductive health in 105 childbearing married women aged 15-49, in Public Health Center 1, Bantul, Yogyakarta. Women's Perception of Males Involvement in Maternal Healthcare Questionnaire was modified and validated to collect the women perception based on health condition, health services, and financial status. Purposive sampling technique was used in this study. The result shows that majority of the women agree that decision making should be done by both husband and wife (99%). Most women (63.8%) believe that selection of health care facilities should be considered with the completeness of the medical services needed and the comfortable place (84.8%). The recommendation from this study is position equality and status between men and women in decision making. Therefore, women are encouraged to be more courageous in expressing their opinions as a form of their involvement in decision making of their health. Keywords— Women perception, husbands support,reproductive.
丈夫参与生殖健康是一个复杂的社会和行为改变过程。在印度尼西亚,由于各种原因,男性在妇女健康方面的作用非常低,这些原因在印度尼西亚社会中根深蒂固,这种社会往往是父权制的,特别是在爪哇人身上。这项描述性研究的目的是描述在日惹班图尔第一公共卫生中心的105名15-49岁育龄已婚妇女中,妇女对丈夫支持作出与妇女生殖健康有关的决定的看法。对《女性对男性参与孕产妇保健的看法》问卷进行了修改和验证,以收集女性基于健康状况、卫生服务和经济状况的看法。本研究采用目的抽样技术。结果显示,大多数女性认为决策应该由丈夫和妻子共同做出(99%)。大多数妇女(63.8%)认为,在选择卫生保健设施时应考虑所需医疗服务的完备性和舒适的地方(84.8%)。这项研究的建议是男性和女性在决策中的地位平等。因此,鼓励妇女更勇敢地表达自己的意见,作为她们参与有关其健康的决策的一种形式。关键词:女性感知,丈夫支持,生育。
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引用次数: 1
The Effect of Mackerel Meat on the Number of Purkinje Cell in the Cerebellum of Congenital Hypothyroid Rat (Rattus norvegicus) 鲭鱼肉对先天性甲状腺功能减退大鼠小脑浦肯野细胞数量的影响
I. Darmawati, R. Saputro, Zulkhah Noor
Early detection through screening of congenital hypothyroid is not a regular program of the government. so that cases of congenital hypothyroid can not be managed appropriately. Therefore, it needs to be done the research .about the benefits of the granting of a bloated fish containing omega3 on congenital hypothyroid as a food supplement to stimulate nerve growth especially brain development. The sample of this research is the droppings of a white rat (Rattus norvegicus).The 30 rats are divided into 6 groups consisting of 5 rats. Four groups was induced with hypothyroid on the day 5 of gestation until nenonatus of the day 15, ..and two other groups .stayed normally.Thyroxine and mackerel meat were given on the 21st day after the birth until the 8th week. Histology and preparations werw made of cells Purkinje after being observed in the cerebellum. The number of Purkinje cells was analized with One-way Anova continued with multiple comparison test. The result is that the number of Purkinje cells in the normal group, normal + mackerel, hypothyroid, hypothyroid + mackerel, hypothyroid treatment with thyroxine, and thyroxine treatment with hypothyroid + mackerel are as follows: 60±12, 71±16, 40±6, 64±7, 70±5, and 65±20. The average number of Purkinje cells in the group that got mackerel significantly (p<0,05) increases compared to hypothyroid. The conclusion is that the supplementation of mackerel fish increases the number of Purkinje cells in the cerebellum of the rat with congenital hypothyroid.
通过筛查早期发现先天性甲状腺功能减退症并不是政府的常规项目。因此,先天性甲状腺功能低下的病例不能得到适当的处理。因此,有必要对含有欧米伽3的膨大鱼类作为食物补充剂对先天性甲状腺功能减退的益处进行研究,以刺激神经生长,尤其是大脑发育。本研究的样本是白鼠(褐家鼠)的粪便。30只大鼠分为6组,每组5只大鼠。4组小鼠在妊娠第5天至第15天分娩时进行甲状腺功能减退诱导。另外两组。正常停留。产后第21天开始给予甲状腺素和鲭鱼肉,直至第8周。在小脑内观察浦肯野细胞后,对其进行组织学和制备。浦肯野细胞数分析采用单因素方差分析,继续进行多重比较检验。结果正常组、正常+青花鱼、甲状腺功能减退组、甲状腺功能减退组+青花鱼、甲状腺素治疗组、甲状腺素治疗组+青花鱼浦肯野细胞数分别为:60±12、71±16、40±6、64±7、70±5、65±20。与甲状腺功能减退组相比,鲭鱼组浦肯野细胞平均数量显著增加(p< 0.05)。由此可见,补充鲭鱼可增加先天性甲状腺功能减退大鼠小脑浦肯野细胞的数量。
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引用次数: 0
Sea Cucumber As An Alternative Supplement In Increasing Bone Health 海参作为促进骨骼健康的替代补充剂
Meiky Fredianto, Nicko Rachmanio, M. Dias
Nutrition is an important factor in maintaining bone health, such as calcium, magnesium, phosphorus, protein, and iron. Sea cucumber is one of sea creatures that has plenty of nutrition which is for the body. Objective : To compare the nutrition of Susu sea cucumber, Gosok sea cucumber, Gamat sea cucumber, and packaged milk so they can be used as alternative source in bone health. Methods : The in vitro test using three samples of sea cucumber and three different kinds of packaged milk for kids. The test was performed to five nutritions e.g. calcium, magnesium, phospor, protein, and iron. The analysis results used independent sample test methode and anova test. Results : Sea cucumbers can meet the number of daily nutritional needs. Calcium in sea cucumbers is higher than that of milk (95% CI: -1969.85354 4094.26021). Its phosphorus is higher than that in milk (95% CI: -224.68925). Its magnesium is higher than that in milk (95% CI: 1499.67724 3243.20276). Its protein is higher than that in milk (95% CI: 18.71876 67.70790). Its iron is higher than that in milk (95% CI: 25.08204 54.45796). Conclusion : The nutrition in sea cucumber is greater than that in packaged milk. Susu sea cucumber is better than that in the other two types. Sea cucumber could be used as alternative source for bone health. Keywords— Susu sea cucumber; Gosok sea cucumber; Gamat sea cucumber; packaged milk; bone health; recommended dietary allowance.
营养是维持骨骼健康的重要因素,如钙、镁、磷、蛋白质和铁。海参是一种营养丰富的海洋生物,对人体有益。目的:比较苏苏海参、古索海参、伽玛特海参和包装奶的营养价值,为其作为骨骼健康的替代来源提供参考。方法:采用三种海参样品和三种不同包装的儿童牛奶进行体外试验。试验对象为钙、镁、磷、蛋白质、铁等5种营养物。分析结果采用独立样本检验方法和方差分析检验。结果:海参能满足每天的营养需求。海参中的钙含量高于牛奶(95% CI: -1969.85354 4094.26021)。其磷含量高于牛奶(95% CI: -224.68925)。它的镁含量高于牛奶(95% CI: 1499.67724 3243.20276)。其蛋白质含量高于牛奶(95% CI: 18.71876 67.70790)。它的铁含量高于牛奶(95% CI: 25.08204 54.45796)。结论:海参的营养价值高于包装奶。苏苏海参的品质优于其他两种海参。海参可作为骨骼健康的替代来源。关键词:宿苏海参;海参;伽玛海参;包装牛奶;骨骼健康;推荐膳食摄入量。
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引用次数: 1
The Effect of Psychoeducation Therapy on Mothers’ Behavior in Providing Nutrition to Infants Aged 0-6 Months in The Community Empowerment Agency of Sri Astutik, S.St., Warungering, Kedungpring, Lamongan 心理教育治疗对母亲0-6月龄婴儿营养行为的影响、华陵岭、洞泉、拉蒙干
Heny Ekawati, D. Martini, Lilis Maghfuroh
Psychoeducation Therapy is a life skill training providing psychological information services either individually or in groups to improve a client's ability in providing nutrition to infants aged 0-6 months. The purpose of this study was to determine the effect of the group psychoeducation on mothers’ behavior in providing nutrition to infants aged 06 months. The design of this study was a pre-experimental one group pretest-posttest design, with a simple random sampling technique. The sample comprised of 39 respondents of nursing mothers in the community empowerment agency (BPM) of Sri Astutik, S.ST, Warungering, Kedungpring, Lamongan. Data collection was carried out in January-March 2018 using a closed questionnaire, and analyzed using the Wilcoxon test. The results showed that prior to psychoeducation, mothers’ behavior in providing nutrition was not good (56.4%), while after psychoeducation almost all (84.6%) mothers’ behavior was good. The Z value = -4.000 with a significant level of 0.000 (p <0.05) indicated that there was an effect of psychoeducation on mothers’ behavior in providing nutrition to infants aged 0-6 months at BPM of Sri Astutik, S.ST, Warungering, Kedungpring, Lamongan. Thus, psychoeducation therapy can be performed to increase knowledge about providing appropriate nutrition to infants aged 0-6 months. Keywords—behavior, nutrition, psychoeducation therapy
心理教育治疗是一种生活技能培训,提供个人或团体心理信息服务,以提高客户为0-6个月婴儿提供营养的能力。摘要本研究旨在探讨团体心理教育对母亲为6月龄婴儿提供营养行为的影响。本研究采用实验前一组前测后测设计,采用简单的随机抽样技术。样本包括来自Sri Astutik, s.s.st, Warungering, Kedungpring, Lamongan的社区赋权机构(BPM)的39名哺乳母亲。数据收集于2018年1月至3月进行,采用封闭式问卷,并使用Wilcoxon测试进行分析。结果表明,心理教育前母亲提供营养行为不佳(56.4%),而心理教育后几乎全部(84.6%)母亲提供营养行为良好。Z值= -4.000,显著性水平为0.000 (p <0.05),表明心理教育对斯里阿斯图提克、s.s.st、沃令林、克东普林、拉蒙干BPM中0-6月龄婴儿的营养行为有影响。因此,可以进行心理教育治疗,以增加对0-6个月婴儿提供适当营养的知识。关键词:行为;营养;心理教育
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Proceedings of the Third International Conference on Sustainable Innovation 2019 – Health Science and Nursing (IcoSIHSN 2019)
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