Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.366
Jiwon Park, Beom-joon Lee, J. Shin, Su-Hyun Chin, Jung-min Yang, Soo-Hyun Kim, Kwan-il Kim, H. Choi, H. Jung
Objective: In this study, a questionnaire survey was conducted for doctors and patients to obtain basic data necessary for the development of an integrated medical system for idiopathic pulmonary fibrosis (IPF).Methods: Questionnaires were developed separately for doctors and patients through an expert group meeting. The survey subjects were recruited online and offline, and finally, responses from 231 doctors and 59 patients were used for statistical analysis.Results: The most important parts in the treatment of IPF for both doctors and patients were the “improvement of respiratory symptoms,” “improvement of quality of life,” and “prevention of disease progression.” Antifibrotic agents were prescribed at a high rate, and 100% of the specialists in Western medicine (WM) and 45.8% of patients reported experiencing side effects. As for the additional payment costs that patients considered as affordable for an integrated medical system, “under 50,000 won (about 38$)” was reported the most in both doctor and patient groups. With regard to the reasons for their reluctance to recommend an integrated medical system for IPF, specialists in WM responded highly to “uncertain evidence for treatment effectiveness.” Regarding complementary and alternative medicine therapies that can be beneficial in patients with IPF, “lifestyle management,” “diet management,” “herb,” “relaxation therapy,” and “psychotherapy” were ranked high in both doctor and patient groups.Conclusions: In this study, a questionnaire survey on IPF was conducted to review actual treatment status, analyze shortcomings, and identify considerations for the development of an integrated medical system for IPF in the future.
{"title":"Research for the Development of an Integrated Medical System for Idiopathic Pulmonary Fibrosis: Based on an Analysis of Questionnaire Survey in Doctor and Patient Groups","authors":"Jiwon Park, Beom-joon Lee, J. Shin, Su-Hyun Chin, Jung-min Yang, Soo-Hyun Kim, Kwan-il Kim, H. Choi, H. Jung","doi":"10.22246/jikm.2023.44.3.366","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.366","url":null,"abstract":"Objective: In this study, a questionnaire survey was conducted for doctors and patients to obtain basic data necessary for the development of an integrated medical system for idiopathic pulmonary fibrosis (IPF).Methods: Questionnaires were developed separately for doctors and patients through an expert group meeting. The survey subjects were recruited online and offline, and finally, responses from 231 doctors and 59 patients were used for statistical analysis.Results: The most important parts in the treatment of IPF for both doctors and patients were the “improvement of respiratory symptoms,” “improvement of quality of life,” and “prevention of disease progression.” Antifibrotic agents were prescribed at a high rate, and 100% of the specialists in Western medicine (WM) and 45.8% of patients reported experiencing side effects. As for the additional payment costs that patients considered as affordable for an integrated medical system, “under 50,000 won (about 38$)” was reported the most in both doctor and patient groups. With regard to the reasons for their reluctance to recommend an integrated medical system for IPF, specialists in WM responded highly to “uncertain evidence for treatment effectiveness.” Regarding complementary and alternative medicine therapies that can be beneficial in patients with IPF, “lifestyle management,” “diet management,” “herb,” “relaxation therapy,” and “psychotherapy” were ranked high in both doctor and patient groups.Conclusions: In this study, a questionnaire survey on IPF was conducted to review actual treatment status, analyze shortcomings, and identify considerations for the development of an integrated medical system for IPF in the future.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77021987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.523
Han-nah Chae, S. Chun, Y. Shin
Objectives: This study aims to investigate the anti-inflammatory effect and improvement of dyslipidemia on Hyangsapyeongwi-san.Methods: In this study, HUVEC cells were cultured and treated with Hyangsapyeongwi-san to measure intracellular KLF2, eNOS, MCP-1, ICAM-1, and VCAM-1 gene expression levels related to anti-inflammation. The weight of experimental animals administered with Hyangsapyeongwi-san was measured, blood samples were biochemically analyzed, and liver tissues were reviewed to research histological changes.Results: Gene expression levels in the cells treated with Hyangsapyeongwi-san generally showed a meaningful anti-inflammatory effect. The body weight of the experimental animals decreased, and total cholesterol, triglyceride, and LDL-cholesterol in the blood generally declined while HDL-cholesterol tended to increase. Fat accumulation between hepatocytes was also reduced after the administration of Hyangsapyeongwi-san.Conclusions: This study confirmed that Hyangsapyeongwi-san has the effect of suppressing vascular inflammatory responses through the regulation of genes involved in the vascular inflammatory process and improving dyslipidemia through the reduction of blood lipids and weight loss.
{"title":"A Study on the Anti-Inflammatory Effect and Improvement of Dyslipidemia on Hyangsapyeongwi-san","authors":"Han-nah Chae, S. Chun, Y. Shin","doi":"10.22246/jikm.2023.44.3.523","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.523","url":null,"abstract":"Objectives: This study aims to investigate the anti-inflammatory effect and improvement of dyslipidemia on Hyangsapyeongwi-san.Methods: In this study, HUVEC cells were cultured and treated with Hyangsapyeongwi-san to measure intracellular KLF2, eNOS, MCP-1, ICAM-1, and VCAM-1 gene expression levels related to anti-inflammation. The weight of experimental animals administered with Hyangsapyeongwi-san was measured, blood samples were biochemically analyzed, and liver tissues were reviewed to research histological changes.Results: Gene expression levels in the cells treated with Hyangsapyeongwi-san generally showed a meaningful anti-inflammatory effect. The body weight of the experimental animals decreased, and total cholesterol, triglyceride, and LDL-cholesterol in the blood generally declined while HDL-cholesterol tended to increase. Fat accumulation between hepatocytes was also reduced after the administration of Hyangsapyeongwi-san.Conclusions: This study confirmed that Hyangsapyeongwi-san has the effect of suppressing vascular inflammatory responses through the regulation of genes involved in the vascular inflammatory process and improving dyslipidemia through the reduction of blood lipids and weight loss.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79772321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.536
Do-yeon Park, Hyangra Moon, Hui-jeong Noh, Sang-yoon Jeon
Objectives: The purpose of this study was to report the effectiveness of Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment in the management of chronic prostatitis/chronic pelvic pain syndrome.Methods: A patient with chronic prostatitis/chronic pelvic pain syndrome underwent Korean medical treatment, including Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment. The severity of symptoms was assessed with a daily visual analog scale (VAS) for orchialgia and lower abdominal pain. In addition, we measured the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) on the first and last days of visit.Results: The patient’s symptoms were improved after treatment. The severity of orchialgia was reduced from VAS7 to VAS2, and lower abdominal pain was improved from VAS6 to VAS1. NIH-CPSI decreased from 21 to 5.Conclusion: Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment are effective in treating chronic prostatitis /chronic pelvic pain syndrome.
{"title":"A Case Report of Chronic Prostatitis/Chronic Pelvic Pain Syndrome Treated with Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment","authors":"Do-yeon Park, Hyangra Moon, Hui-jeong Noh, Sang-yoon Jeon","doi":"10.22246/jikm.2023.44.3.536","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.536","url":null,"abstract":"Objectives: The purpose of this study was to report the effectiveness of Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment in the management of chronic prostatitis/chronic pelvic pain syndrome.Methods: A patient with chronic prostatitis/chronic pelvic pain syndrome underwent Korean medical treatment, including Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment. The severity of symptoms was assessed with a daily visual analog scale (VAS) for orchialgia and lower abdominal pain. In addition, we measured the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) on the first and last days of visit.Results: The patient’s symptoms were improved after treatment. The severity of orchialgia was reduced from VAS7 to VAS2, and lower abdominal pain was improved from VAS6 to VAS1. NIH-CPSI decreased from 21 to 5.Conclusion: Hoeeum Bee-venom Therapy and Balio Acupuncture Treatment are effective in treating chronic prostatitis /chronic pelvic pain syndrome.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80057199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.354
S. Oh, Woo-nyoung Jung, Mee-ryoung Song, Ji-Won Noh, Young-min Ahn, Se-young Ahn, Byung-Cheol Lee
Objective: This study aimed to assess the safety and effect on glucose level of Bojungikgi-tang in patients with type 2 diabetes mellitus.Methods: To review patients’ clinical characteristics and laboratory tests retrospectively, we investigated 15 hospitalized patients with type 2 diabetes mellitus who took Bojungikgi-tang at Kyung Hee University Korean Medical Hospital for at least one day between January 2012 and December 2022. The blood glucose levels, including fasting blood sugar (FBS), 2-hour postprandial glucose (PP2) levels, and glycated hemoglobin level, were collected to determine the effect of the Bojungikgi-tang on blood sugar changes. Furthermore, to evaluate the safety of Bojungikgi-tang, hepatic function and renal function tests were implemented, including aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, γ-glutamyltransferase, blood urea nitrogen, creatinine, and Modification of Diet in Renal Disease estimated glomerular filtration rate.Results: When Bojungikgi-tang and a standard treatment for diabetes were administered for patients with type 2 diabetes, it was confirmed that there were no statistically significant changes in FBS and PP2 levels in the analysis of each medication taken. There was no significant difference in the safety profile after taking Bojungikgi-tang.Conclusions: The combined administration of Bojungikgi-tang with standard hypoglycemic medication for patients with type 2 diabetes may not affect blood glucose levels and safety.
{"title":"A Retrospective Study of the Safety and Effect of Co-administration of Glucose-lowering Medication and Bojungikgi-tang on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus","authors":"S. Oh, Woo-nyoung Jung, Mee-ryoung Song, Ji-Won Noh, Young-min Ahn, Se-young Ahn, Byung-Cheol Lee","doi":"10.22246/jikm.2023.44.3.354","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.354","url":null,"abstract":"Objective: This study aimed to assess the safety and effect on glucose level of Bojungikgi-tang in patients with type 2 diabetes mellitus.Methods: To review patients’ clinical characteristics and laboratory tests retrospectively, we investigated 15 hospitalized patients with type 2 diabetes mellitus who took Bojungikgi-tang at Kyung Hee University Korean Medical Hospital for at least one day between January 2012 and December 2022. The blood glucose levels, including fasting blood sugar (FBS), 2-hour postprandial glucose (PP2) levels, and glycated hemoglobin level, were collected to determine the effect of the Bojungikgi-tang on blood sugar changes. Furthermore, to evaluate the safety of Bojungikgi-tang, hepatic function and renal function tests were implemented, including aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, γ-glutamyltransferase, blood urea nitrogen, creatinine, and Modification of Diet in Renal Disease estimated glomerular filtration rate.Results: When Bojungikgi-tang and a standard treatment for diabetes were administered for patients with type 2 diabetes, it was confirmed that there were no statistically significant changes in FBS and PP2 levels in the analysis of each medication taken. There was no significant difference in the safety profile after taking Bojungikgi-tang.Conclusions: The combined administration of Bojungikgi-tang with standard hypoglycemic medication for patients with type 2 diabetes may not affect blood glucose levels and safety.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89397805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.313
Subin Park, Y. Kim, Gi-Sang Bae, Cheol-hyun Kim, Inae Youn, Jungtae Leem, H. Chu
Objectives: Heart failure is a chronic disease with increasing prevalence rates despite advancements in medical technology. Korean medicine utilizes herbal prescriptions to treat heart failure, but little is known about the specific herbal medicines comprising the network of herbal prescriptions for heart failure. This study proposes a novel methodology that can efficiently develop prescriptions and facilitate experimental research on heart failure by utilizing existing databases.Methods: Herbal medicine prescriptions for heart failure were identified through a PubMed search and compiled into a Google Sheet database. NetMiner 4 was used for network analysis, and the individual networks were classified according to the herbal medicine classification system to identify trends. K-HERB NETWORK was utilized to derive related prescriptions.Results: Network analysis of heart failure prescriptions and herbal medicines using NetMiner 4 produced 16 individual networks. Uhwangcheongsim-won (牛黃淸心元), Gamiondam-tang (加味溫膽湯), Bangpungtongseong-san (防風通聖散), and Bunsimgi-eum (分心氣飮) were identified as prescriptions with high similarity in the entire network. A total of 16 individual networks utilized K-HERB NETWORK to present prescriptions that were most similar to existing prescriptions. The results provide 1) an indication of existing prescriptions with potential for use to treat heart failure and 2) a basis for developing new prescriptions for heart failure treatment.Conclusion: The proposed methodology presents an efficient approach to developing new heart failure prescriptions and facilitating experimental research. This study highlights the potential of network pharmacology methodology and its possible applications in other diseases. Further studies on network pharmacology methodology are recommended.
{"title":"Network Analysis Using the Established Database (K-herb Network) on Herbal Medicines Used in Clinical Research on Heart Failure","authors":"Subin Park, Y. Kim, Gi-Sang Bae, Cheol-hyun Kim, Inae Youn, Jungtae Leem, H. Chu","doi":"10.22246/jikm.2023.44.3.313","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.313","url":null,"abstract":"Objectives: Heart failure is a chronic disease with increasing prevalence rates despite advancements in medical technology. Korean medicine utilizes herbal prescriptions to treat heart failure, but little is known about the specific herbal medicines comprising the network of herbal prescriptions for heart failure. This study proposes a novel methodology that can efficiently develop prescriptions and facilitate experimental research on heart failure by utilizing existing databases.Methods: Herbal medicine prescriptions for heart failure were identified through a PubMed search and compiled into a Google Sheet database. NetMiner 4 was used for network analysis, and the individual networks were classified according to the herbal medicine classification system to identify trends. K-HERB NETWORK was utilized to derive related prescriptions.Results: Network analysis of heart failure prescriptions and herbal medicines using NetMiner 4 produced 16 individual networks. Uhwangcheongsim-won (牛黃淸心元), Gamiondam-tang (加味溫膽湯), Bangpungtongseong-san (防風通聖散), and Bunsimgi-eum (分心氣飮) were identified as prescriptions with high similarity in the entire network. A total of 16 individual networks utilized K-HERB NETWORK to present prescriptions that were most similar to existing prescriptions. The results provide 1) an indication of existing prescriptions with potential for use to treat heart failure and 2) a basis for developing new prescriptions for heart failure treatment.Conclusion: The proposed methodology presents an efficient approach to developing new heart failure prescriptions and facilitating experimental research. This study highlights the potential of network pharmacology methodology and its possible applications in other diseases. Further studies on network pharmacology methodology are recommended.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76287303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.439
Min-hwa Kim, Im-hak Cho, Inju Nam, Maria Kim, Ki-beom Ku, Se-yeon Lee, J. Kwon, In Lee, Jin-woo Hong, Y. Yun, So-Yeon Kim, Chang-woo Han, So-jung Park, Jun-Yong Choi, Hyeun-kyoo Shin
Objectives: As Korea transitions into an aging society, the incidence of cerebrovascular disease is expected to increase. Herbal medicine is commonly used in Oriental medicine to treat cerebrovascular disease. However, there is insufficient clinical evidence to actively support the safety of herbal medicine in clinical practice. Therefore, the aim of this study was to determine the toxicity and safety of four herbal medicines (Cheongsimyeonja-tang, Dodam-tang, Hyeolbuchukso-tang, and Boshiniknai-tang) in patients with cerebrovascular disease.Methods: This study used electronic medical records to analyze patients admitted to an oriental medicine hospital from April 1, 2017, to December 31, 2020. Liver and renal function values at the time of admission and discharge were compared.Results: A total of 25 patients were included in this study. We found no significant differences in various variables, such as complete blood count, liver-renal function test, and urine, before and after the administration of the four herbal medicines. Additionally, no significant adverse events related to herbal medicine were observed.Conclusions: This study confirmed the safety of the four herbal medicines in patients with cerebrovascular disease who were hospitalized in a single Oriental medicine hospital.
{"title":"Hepatic/Renal Safety Evaluation of Cheongsimyeonja-tang (Qīngxīn Liánzǎo Tāng), Dodam-tang (Táodàn Tāng), Hyeolbuchukso-tang (Xuè Fǔ Zhú Yū Tāng), and Boshiniknai-tang (Bǔ Shèn Yì Nǎo Tāng) for Cerebrovascular Diseases: A Retrospective Study","authors":"Min-hwa Kim, Im-hak Cho, Inju Nam, Maria Kim, Ki-beom Ku, Se-yeon Lee, J. Kwon, In Lee, Jin-woo Hong, Y. Yun, So-Yeon Kim, Chang-woo Han, So-jung Park, Jun-Yong Choi, Hyeun-kyoo Shin","doi":"10.22246/jikm.2023.44.3.439","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.439","url":null,"abstract":"Objectives: As Korea transitions into an aging society, the incidence of cerebrovascular disease is expected to increase. Herbal medicine is commonly used in Oriental medicine to treat cerebrovascular disease. However, there is insufficient clinical evidence to actively support the safety of herbal medicine in clinical practice. Therefore, the aim of this study was to determine the toxicity and safety of four herbal medicines (Cheongsimyeonja-tang, Dodam-tang, Hyeolbuchukso-tang, and Boshiniknai-tang) in patients with cerebrovascular disease.Methods: This study used electronic medical records to analyze patients admitted to an oriental medicine hospital from April 1, 2017, to December 31, 2020. Liver and renal function values at the time of admission and discharge were compared.Results: A total of 25 patients were included in this study. We found no significant differences in various variables, such as complete blood count, liver-renal function test, and urine, before and after the administration of the four herbal medicines. Additionally, no significant adverse events related to herbal medicine were observed.Conclusions: This study confirmed the safety of the four herbal medicines in patients with cerebrovascular disease who were hospitalized in a single Oriental medicine hospital.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75535601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.506
Seungbo Yang, A. Jeong
COVID-19 is an acute infectious disease caused by SARS-CoV-2 that has infected more than 700 million people around the world and left many deaths. In Korea and China, Korean medicine and Traditional Chinese Medicine were used to treat COVID-19, and the key element between them was herbal medicine. Clinical guidelines for herbal medicine have been published in Korea and China. In this review, the Korean and Chinese guidelines were compared and analyzed. This review was based on the latest revised clinical guidelines. The Korean guidelines covered all three guidelines published by The Association of Korean Medicine and The KM Professor Council of Internal Medicine of the Respiratory System. The Chinese guideline was published by the China National Health Commission. Based on research trends, a comprehensive comparison was made of the suggested prescriptions for each severity of COVID-19. It is expected that this review will be used as a reference for the treatment of COVID-19 or new infectious diseases in the future.
{"title":"Analysis of Herbal Medicine in the Clinical Guidelines of Korea and China for COVID-19","authors":"Seungbo Yang, A. Jeong","doi":"10.22246/jikm.2023.44.3.506","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.506","url":null,"abstract":"COVID-19 is an acute infectious disease caused by SARS-CoV-2 that has infected more than 700 million people around the world and left many deaths. In Korea and China, Korean medicine and Traditional Chinese Medicine were used to treat COVID-19, and the key element between them was herbal medicine. Clinical guidelines for herbal medicine have been published in Korea and China. In this review, the Korean and Chinese guidelines were compared and analyzed. This review was based on the latest revised clinical guidelines. The Korean guidelines covered all three guidelines published by The Association of Korean Medicine and The KM Professor Council of Internal Medicine of the Respiratory System. The Chinese guideline was published by the China National Health Commission. Based on research trends, a comprehensive comparison was made of the suggested prescriptions for each severity of COVID-19. It is expected that this review will be used as a reference for the treatment of COVID-19 or new infectious diseases in the future.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77485080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.585
Kyung-dug Park, Jisoo Kim, Yoona Oh, B. Jeong, Y. Jung, Sunhwi Bang
Objective: The purpose of this study is to report the effect of integrative medicine on recurrent follicular lymphoma, thus providing a clinical basis for integrative medicine.Methods: The medical report of a patient with follicular lymphoma who had undergone several chemotherapies but continuously relapsed before treated with integrative medicine was analyzed. Radiologic outcome was assessed by several imaging tests based on Response Evaluation Criteria in Solid Tumors. Clinical outcome and safety were assessed by laboratory tests.Results: After five years of integrative treatment, there was a complete response in imaging tests such as computed tomography (CT), positron-emission tomography/CT, and endoscopy. There were no toxicity in the laboratory test and no serious side effect of integrative medicine.Conclusion: This study suggested that integrative medicine has few side effects but significant effects on treating recurrent follicular lymphoma. However, the results should be taken cautiously as further clinical studies are needed.
{"title":"A Case Report on the Complete Response of a Patient with Recurrent Follicular Lymphoma Treated with Integrative Medicine","authors":"Kyung-dug Park, Jisoo Kim, Yoona Oh, B. Jeong, Y. Jung, Sunhwi Bang","doi":"10.22246/jikm.2023.44.3.585","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.585","url":null,"abstract":"Objective: The purpose of this study is to report the effect of integrative medicine on recurrent follicular lymphoma, thus providing a clinical basis for integrative medicine.Methods: The medical report of a patient with follicular lymphoma who had undergone several chemotherapies but continuously relapsed before treated with integrative medicine was analyzed. Radiologic outcome was assessed by several imaging tests based on Response Evaluation Criteria in Solid Tumors. Clinical outcome and safety were assessed by laboratory tests.Results: After five years of integrative treatment, there was a complete response in imaging tests such as computed tomography (CT), positron-emission tomography/CT, and endoscopy. There were no toxicity in the laboratory test and no serious side effect of integrative medicine.Conclusion: This study suggested that integrative medicine has few side effects but significant effects on treating recurrent follicular lymphoma. However, the results should be taken cautiously as further clinical studies are needed.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78288683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.562
Yu-jin Jung, Jisoo Kim, Kyung-dug Park, Yoona Oh, B. Jeong, Sunhwi Bang
Objectives: This is a five-year survival and complete response (CR) report on pancreatic cancer treated with western medicine and Korean traditional medicine.Method: A 59-year-old woman diagnosed with pancreatic cancer visited ⃝⃝ Korean traditional medicine hospital after neoadjuvant chemotherapy and pylorus-preserving pancreaticoduodenectomy. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from March 2018 to September 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0.Result: During four years and three months of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on October 26, 2022.Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for pancreatic cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for pancreatic cancer.
{"title":"Case Report on the Five-year Survival and Complete Response of a Patient with Pancreatic Cancer Treated with Integrative Medicine","authors":"Yu-jin Jung, Jisoo Kim, Kyung-dug Park, Yoona Oh, B. Jeong, Sunhwi Bang","doi":"10.22246/jikm.2023.44.3.562","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.562","url":null,"abstract":"Objectives: This is a five-year survival and complete response (CR) report on pancreatic cancer treated with western medicine and Korean traditional medicine.Method: A 59-year-old woman diagnosed with pancreatic cancer visited ⃝⃝ Korean traditional medicine hospital after neoadjuvant chemotherapy and pylorus-preserving pancreaticoduodenectomy. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from March 2018 to September 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0.Result: During four years and three months of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on October 26, 2022.Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for pancreatic cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for pancreatic cancer.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77074123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.22246/jikm.2023.44.3.418
Seong-Cheon Woo, Su-Won Lee, Yang-Chun Park
Objective: This study was conducted to review the effects of herbal medicine on respiratory diseases induced by the treatment of particulate matter in in vivo animal models.Methods: Literature searches were performed in seven databases (Pubmed, Embase, Cochrane Library, KISS, KTKP, OASIS, and ScienceON). After the searched studies were screened based on the inclusion/exclusion criteria, the publication date, origin, used animals, induction of particulate matter models, herbal medicine used for intervention, study design, outcome measure, and results of studies were analyzed.Results: Among a total of 972 studies primarily searched, 34 studies were finally included in our study. Of this number, 29 studies induced animal models by using only particulate matter, and 5 studies induced animal models with respiratory diseases, such as asthma and chronic obstructive pulmonary disease, by using particulate matter and other materials. In the selected studies, the treatments of herbal medicine in particulate matter models suppressed oxidative stress and inflammation in lung tissue, bronchoalveolar lavage fluid, and blood as well as lung injury in histological analysis.Conclusion: The results of this study suggest that herbal medicine is effective in treating respiratory diseases induced by particulate matter. These results are also expected to be useful data for designing further studies. However, more systematically designed in vivo studies related to particulate matter are needed.
{"title":"Review on the Effects of Herbal Medicine on Respiratory Diseases in In Vivo Particulate Matter Models","authors":"Seong-Cheon Woo, Su-Won Lee, Yang-Chun Park","doi":"10.22246/jikm.2023.44.3.418","DOIUrl":"https://doi.org/10.22246/jikm.2023.44.3.418","url":null,"abstract":"Objective: This study was conducted to review the effects of herbal medicine on respiratory diseases induced by the treatment of particulate matter in in vivo animal models.Methods: Literature searches were performed in seven databases (Pubmed, Embase, Cochrane Library, KISS, KTKP, OASIS, and ScienceON). After the searched studies were screened based on the inclusion/exclusion criteria, the publication date, origin, used animals, induction of particulate matter models, herbal medicine used for intervention, study design, outcome measure, and results of studies were analyzed.Results: Among a total of 972 studies primarily searched, 34 studies were finally included in our study. Of this number, 29 studies induced animal models by using only particulate matter, and 5 studies induced animal models with respiratory diseases, such as asthma and chronic obstructive pulmonary disease, by using particulate matter and other materials. In the selected studies, the treatments of herbal medicine in particulate matter models suppressed oxidative stress and inflammation in lung tissue, bronchoalveolar lavage fluid, and blood as well as lung injury in histological analysis.Conclusion: The results of this study suggest that herbal medicine is effective in treating respiratory diseases induced by particulate matter. These results are also expected to be useful data for designing further studies. However, more systematically designed in vivo studies related to particulate matter are needed.","PeriodicalId":22826,"journal":{"name":"The Journal of Internal Korean Medicine","volume":"BME-25 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72610869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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