Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.4.25
Sehui Lee, Jin A. Lee, Mi-Rae Shin, J. H. Lee, S. Roh
{"title":"The Protective Effect of Water Extract of Phellodendri Cortex in Chronic Reflux Esophagitis-induced Rats","authors":"Sehui Lee, Jin A. Lee, Mi-Rae Shin, J. H. Lee, S. Roh","doi":"10.6116/KJH.2020.35.4.25","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.4.25","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"32 1","pages":"25-36"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76195569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.4.51
Sangwoo Kim, Sooyeon Hong, Boguen Kwon, M. Kim, Sang-bae Kim, Dae-hwan Jin, Woochan Choi, Youngjoo Sohn, Hyuk-Sang Jung
Objective : The objective of this study was to demonstrate the effect of Persicae Semen (PS) in DNCB–induced atopic dermatitis mouse and HaCaT cell. Methods : The BALB/c mice were divided into four groups. To develop atopic dermatitis, 200 μl of 1 and 0.5% DNCB solution was put on the back of mice in the Control group, the PS-Low group and the PS-High group once a day. After application of DNCB, 200 μl of the PS extract was also treated. The Normal group was given PBS. The mice dorsal skin was stained with Masson's trichrome, H&E, and toluidine blue to evaluate the thickness of the epidermis and dermis, infiltration of eosinophils and mast cells respectively. ELISA was applied to measure the serum level of IgE and IL-6. Toxicity of PS was measured by MTS assay in HaCaT cell. To investigate the effects of PS on HaCaT cells, cells were pre-treated with PS for 1h, and then stimulated with TNF-α and IFN-γ. After 24 hours, the expression of TARC was analyzed using RT-PCR. Results : PS not only significantly diminished the thickness of the epidermis and dermis, but also reduced the infiltration of eosinophil and mast cell in skin lesion. PS also reduced the serum IgE and IL-6 level which plated important roles in the atopic dermatitis. The expression of TARC was decreased significantly in TNF-α/IFN-γ stimulated HaCaT cell. Conclusion : These results suggest that PS may be effective in alleviating the atopic dermatitis induced by DNCB and inflammation by TNF-α/IFN-γ. 1)
{"title":"Effect of Persicae Semen for Atopic Dermatitis Skin Tissue and Regulate to Inflammation Mediator in Serum","authors":"Sangwoo Kim, Sooyeon Hong, Boguen Kwon, M. Kim, Sang-bae Kim, Dae-hwan Jin, Woochan Choi, Youngjoo Sohn, Hyuk-Sang Jung","doi":"10.6116/KJH.2020.35.4.51","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.4.51","url":null,"abstract":"Objective : The objective of this study was to demonstrate the effect of Persicae Semen (PS) in DNCB–induced atopic dermatitis mouse and HaCaT cell. Methods : The BALB/c mice were divided into four groups. To develop atopic dermatitis, 200 μl of 1 and 0.5% DNCB solution was put on the back of mice in the Control group, the PS-Low group and the PS-High group once a day. After application of DNCB, 200 μl of the PS extract was also treated. The Normal group was given PBS. The mice dorsal skin was stained with Masson's trichrome, H&E, and toluidine blue to evaluate the thickness of the epidermis and dermis, infiltration of eosinophils and mast cells respectively. ELISA was applied to measure the serum level of IgE and IL-6. Toxicity of PS was measured by MTS assay in HaCaT cell. To investigate the effects of PS on HaCaT cells, cells were pre-treated with PS for 1h, and then stimulated with TNF-α and IFN-γ. After 24 hours, the expression of TARC was analyzed using RT-PCR. Results : PS not only significantly diminished the thickness of the epidermis and dermis, but also reduced the infiltration of eosinophil and mast cell in skin lesion. PS also reduced the serum IgE and IL-6 level which plated important roles in the atopic dermatitis. The expression of TARC was decreased significantly in TNF-α/IFN-γ stimulated HaCaT cell. Conclusion : These results suggest that PS may be effective in alleviating the atopic dermatitis induced by DNCB and inflammation by TNF-α/IFN-γ. 1)","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"27 1","pages":"51-60"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78301824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.2.47
Hyeon-Hwa Nam, Y. Seo, B. Moon, Ji‐hye Lee, Yongbum Kim, Joong-Sun Kim
{"title":"Effects of a Two-Week-Oral-Toxicity Study of Bombyx batryticatus L. Extracts on C57BL/6 Mice","authors":"Hyeon-Hwa Nam, Y. Seo, B. Moon, Ji‐hye Lee, Yongbum Kim, Joong-Sun Kim","doi":"10.6116/KJH.2020.35.2.47","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.2.47","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"32 1","pages":"47-53"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73362778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.4.17
Hyeon-Hwa Nam, Y. Seo, J. H. Lee, Y. Seo, Sungyu Yang, B. Moon, W. Kim, L. Nan, B. Choo, Joong-Sun Kim
{"title":"Effect on rat model of reflux esophagitis treated with Charybdis japonica extract","authors":"Hyeon-Hwa Nam, Y. Seo, J. H. Lee, Y. Seo, Sungyu Yang, B. Moon, W. Kim, L. Nan, B. Choo, Joong-Sun Kim","doi":"10.6116/KJH.2020.35.4.17","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.4.17","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"15 1","pages":"17-23"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81762716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.6.29
Tae Yeon Kim, K. Leem
{"title":"Effects of Gyejigamchoyonggolmoryeo-tang on sleep latency and total duration of sleep induced by thiopental sodium in mice","authors":"Tae Yeon Kim, K. Leem","doi":"10.6116/KJH.2020.35.6.29","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.6.29","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"66 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75930500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.2.15
S. Shin, E. Doh, Ho-joon Song, Sung-Joo Park, Guemsan Lee
{"title":"A Literature Review on the Origin of Dipsaci Radix and Phlomidis Radix","authors":"S. Shin, E. Doh, Ho-joon Song, Sung-Joo Park, Guemsan Lee","doi":"10.6116/KJH.2020.35.2.15","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.2.15","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"76 1","pages":"15-29"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75162667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lee Jang Cheon, Cho, Su-In, Kim Hyung Woo, Kim Jung-hoon, D. Sung, Lee BooKyun
Objectives : Angelicae gigas, A. sinensis and A. acutiloba are three types of plants used as Angelicae Radix (Dang-Gui). Many doctors of Korean medicine want to know the difference in clinical use of these three species. This study aimed to compare the hemoglobin-related activity of the extracts of Angelicae gigas, A. sinensis and A. acutiloba roots by measuring the intensity of binding oxygen to hemoglobin using Raman spectroscopy. Methods : Hemoglobin activity was measured by chemical analysis and Raman spectroscopy to compare the pharmaceutical efficacy of three Angelica root extracts. The oxygenated hemoglobin intensity, blood decursinol and acetylcholinestrase(AChE) concentration in mice were measured. In addition, the effects of three Angelica root extracts on oxygenated hemoglobin intensity, decursinol and AChE concentration in red blood cells (RBC) from human were also investigated. Results : The contents of decursin, decursinol and decursinol angelate, which affected physiological activity and RBC properties, were higher in the extract of A. gigas root than in those of A. sinensis and A. acutiloba roots. Moreover, oxygenated hemoglobin intensity in the A. gigas extract was higher than that of other two species in the blood of mice and human RBCs. Also, the blood decursinol and AChE concentrations of A. gigas root extract were higher than that of A. sinensis and A. acutiloba roots. Conclusions : These results suggest that A. gigas is more effective in treating disease related oxygen deficiency in RBC deformation under oxidative stress.1)
{"title":"Comparison of Hemoglobin Activity of Angelica gigas, Angelica sinensis and Angelica acutiloba roots","authors":"Lee Jang Cheon, Cho, Su-In, Kim Hyung Woo, Kim Jung-hoon, D. Sung, Lee BooKyun","doi":"10.6116/KJH.2020.35.4.1","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.4.1","url":null,"abstract":"Objectives : Angelicae gigas, A. sinensis and A. acutiloba are three types of plants used as Angelicae Radix (Dang-Gui). Many doctors of Korean medicine want to know the difference in clinical use of these three species. This study aimed to compare the hemoglobin-related activity of the extracts of Angelicae gigas, A. sinensis and A. acutiloba roots by measuring the intensity of binding oxygen to hemoglobin using Raman spectroscopy. Methods : Hemoglobin activity was measured by chemical analysis and Raman spectroscopy to compare the pharmaceutical efficacy of three Angelica root extracts. The oxygenated hemoglobin intensity, blood decursinol and acetylcholinestrase(AChE) concentration in mice were measured. In addition, the effects of three Angelica root extracts on oxygenated hemoglobin intensity, decursinol and AChE concentration in red blood cells (RBC) from human were also investigated. Results : The contents of decursin, decursinol and decursinol angelate, which affected physiological activity and RBC properties, were higher in the extract of A. gigas root than in those of A. sinensis and A. acutiloba roots. Moreover, oxygenated hemoglobin intensity in the A. gigas extract was higher than that of other two species in the blood of mice and human RBCs. Also, the blood decursinol and AChE concentrations of A. gigas root extract were higher than that of A. sinensis and A. acutiloba roots. Conclusions : These results suggest that A. gigas is more effective in treating disease related oxygen deficiency in RBC deformation under oxidative stress.1)","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"20 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84463851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Sung, Young-sil Lee, Seung-Hyung Kim, Dong-Seon Kim
{"title":"BS21, a combination of Phyllostachys pubescens and Scutellaria baicalensis extracts, reduces adiposity and hyperuricemia in high-fat diet-induced obese mice","authors":"Y. Sung, Young-sil Lee, Seung-Hyung Kim, Dong-Seon Kim","doi":"10.6116/KJH.2020.35.5.1","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.5.1","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"4 7","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91443891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.6.21
M. Kim, Mi-Rae Shin, Jin A. Lee, Soonwoo Park, Hae-Jin Park, J. Lee, S. Roh
{"title":"Improvement Effect of Sprout of Coix lacryma-jobi var. mayuen Stapf Water Extract on DSS-Induced Ulcerative Colitis in Mice.","authors":"M. Kim, Mi-Rae Shin, Jin A. Lee, Soonwoo Park, Hae-Jin Park, J. Lee, S. Roh","doi":"10.6116/KJH.2020.35.6.21","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.6.21","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"66 1","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85721504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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