Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.5.23
H. Do, Kyungho Kim, T. Oh
{"title":"Anti-hyperlipidemic Effects of Scutellariae Radix, Aucklandiae Radix and Bupleuri Radix (SAB) extract in FL83B cells","authors":"H. Do, Kyungho Kim, T. Oh","doi":"10.6116/KJH.2020.35.5.23","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.5.23","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"1 1","pages":"23-31"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82882399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective : To identify the effects of the water extract of Liriope platyphylla tuber (Liriopis tuber, LT) on the activation of astocytes, we investigated the regulatory effects of LT extract on H2O2-induced oxidative damage in C6 rat astrocytes. Methods : LT extract was extracted with boiling water. C6 cell line were treated with LT extract at 1, 2, and 3 mg/ml or without for 30 min and then stimulated with H2O2 at 5 μm for 24 hr. The cell viability was measured by MTT assay. The expression of glial fibrillary acidic protein (GFAP), signal transducer and activator of transcription 3 (STAT3), phospho-STAT3 (pSTAT3), cyclooxygenase (COX-2), Nuclear factor-κB (NF-κB), superoxide dismutase 2 (SOD2), heme oxygenase-1 (HO-1), catalase, Akt, phospho-Akt (p-Akt) phosphoinositide 3-kinases (PI3K), and protein kinase C alpha (PKCα) proteins were determined by Western blot, respectively. GFAP expression was also observed with immunocytochemistry under a fluorescence microscope. Results : LT extract induced cell proliferation in H2O2-stimulated C6 cells. LT extract significantly inhibited the expression of GFAP, NF-κB and COX-2 and increased the expression of HO-1 and the phosphorylation of STAT3 in H2O2-stimulated C6 cells. LT extract also significantly increased the phosphorylation of Akt and decreased the expression of PKCα in a dose-dependent manner in H2O2-stimulated C6 cells. Conclusions : LT extract can regulate H2O2-induced activation of astrocytes through inhibiting the expression of NF-κB, COX-2 and regulating Akt / HO-1, STAT3 or PKCα signaling pathway.1)
{"title":"A Study on the Effect of Liriopis tuber water extract on Hydrogen Peroxide-stimulated C6 Astrocyte Cells","authors":"K. Park, S. Kang, H. Jung, Yong-Ki Park","doi":"10.6116/KJH.2020.35.4.9","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.4.9","url":null,"abstract":"Objective : To identify the effects of the water extract of Liriope platyphylla tuber (Liriopis tuber, LT) on the activation of astocytes, we investigated the regulatory effects of LT extract on H2O2-induced oxidative damage in C6 rat astrocytes. Methods : LT extract was extracted with boiling water. C6 cell line were treated with LT extract at 1, 2, and 3 mg/ml or without for 30 min and then stimulated with H2O2 at 5 μm for 24 hr. The cell viability was measured by MTT assay. The expression of glial fibrillary acidic protein (GFAP), signal transducer and activator of transcription 3 (STAT3), phospho-STAT3 (pSTAT3), cyclooxygenase (COX-2), Nuclear factor-κB (NF-κB), superoxide dismutase 2 (SOD2), heme oxygenase-1 (HO-1), catalase, Akt, phospho-Akt (p-Akt) phosphoinositide 3-kinases (PI3K), and protein kinase C alpha (PKCα) proteins were determined by Western blot, respectively. GFAP expression was also observed with immunocytochemistry under a fluorescence microscope. Results : LT extract induced cell proliferation in H2O2-stimulated C6 cells. LT extract significantly inhibited the expression of GFAP, NF-κB and COX-2 and increased the expression of HO-1 and the phosphorylation of STAT3 in H2O2-stimulated C6 cells. LT extract also significantly increased the phosphorylation of Akt and decreased the expression of PKCα in a dose-dependent manner in H2O2-stimulated C6 cells. Conclusions : LT extract can regulate H2O2-induced activation of astrocytes through inhibiting the expression of NF-κB, COX-2 and regulating Akt / HO-1, STAT3 or PKCα signaling pathway.1)","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"41 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82215019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.6116/KJH.2020.35.5.41
J. Koo
{"title":"5 Cases of Primary Infertility treated by Jokyungjongok-tang gamibang","authors":"J. Koo","doi":"10.6116/KJH.2020.35.5.41","DOIUrl":"https://doi.org/10.6116/KJH.2020.35.5.41","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"151 1","pages":"41-46"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84976656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/KJH.2019.34.1.67
정미진, 김소영, 도은주, 윤종국, 김대익, 한경수, Mi Ryeo Kim
{"title":"The effect of herbal mixture on alcohol metabolism in Sprague Dawley rats","authors":"정미진, 김소영, 도은주, 윤종국, 김대익, 한경수, Mi Ryeo Kim","doi":"10.6116/KJH.2019.34.1.67","DOIUrl":"https://doi.org/10.6116/KJH.2019.34.1.67","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"28 1","pages":"67-74"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88435904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young-Sik Kim, Chun-Geon Park, G. Choi, Jae-Ki Chang, J. Lee, Young-sung Ju
Objectives : The consumption of licorice is large in Korea, but domestic production is insufficient due to the lack of adaptability. This study aimed to provide a morphological basis for adding interspecific hybrid licorice with improved adaptability to pharmacopoeia. Methods : This study was to establish identification criteria for the original plants, external and internal morphology of the authentic herbal medicines (Glycyrrhiza uralensis, G. glabra and G. inflata), market products and artificially interspecific hybrid forms of licorice. For this purpose, previous studies were investigated and visual and histological observations were carried out. We focused on the internal morphology by microscopic observation for securing objectivity. Finally, we proposed the identification keys for precise classification of each part. Results : 1) Original plant : Licorice species in the compendium were distinguished by the number of leaflets, presence of hair on the fruit, curvature and swelling of the fruit. 2) External morphology : Licorice species were distinguished by degree of powderiness, tearing gap, radial structure in the cross section and existence of protrusion of outer epidermis. 3) Internal morphology : Licorice species were distinguished by the degree of development of phloem fiber bundle, development of obliterated sieve, whether the secondary medullary ray are branched. In the case of interspecific hybrids, the characteristics of both species used for hybridization were mixed in all observation methods. Conclusions : These results suggest that the interspecific crossbred licorice is suitable for the pharmacopoeial standard. Therefore, it can be applied as a herbal medicine through additional supplementary study.
目的:韩国甘草消费量大，但由于适应性不足，国内产量不足。本研究旨在为添加种间杂交甘草提高药典适应性提供形态学依据。方法:建立正宗药材甘草(glycyrhiza uralensis, G. glabra, G. inflata)、市场产品和人工种间杂交甘草的原植物、内外形态鉴别标准。为此，我们调查了以往的研究，并进行了视觉和组织学观察。为了保证客观性，我们通过显微观察来关注内部形态。最后，提出了对各部件进行精确分类的识别关键字。结果:1)原植物:通过小叶数量、果实上是否有毛、果实的弯曲和膨大来区分本纲目中甘草的种类。2)外表皮形态:甘草品种以粉末状程度、撕裂间隙、横截面呈放射状结构、外表皮是否有突出来区分。3)内部形态:通过韧皮部纤维束的发育程度、残筛的发育程度、次生髓线是否有分支来区分甘草种类。在种间杂交的情况下，所有观察方法都混合了用于杂交的两个物种的特征。结论:种间杂交甘草符合药典标准。因此，通过进一步的补充研究，它可以作为草药应用。
{"title":"Comparative study of external-intenal morphological shape in origins and hybrids for Glycyrrhizae Radix et Rhizoma","authors":"Young-Sik Kim, Chun-Geon Park, G. Choi, Jae-Ki Chang, J. Lee, Young-sung Ju","doi":"10.6116/KJH.2019.34.5.1","DOIUrl":"https://doi.org/10.6116/KJH.2019.34.5.1","url":null,"abstract":"Objectives : The consumption of licorice is large in Korea, but domestic production is insufficient due to the lack of adaptability. This study aimed to provide a morphological basis for adding interspecific hybrid licorice with improved adaptability to pharmacopoeia. Methods : This study was to establish identification criteria for the original plants, external and internal morphology of the authentic herbal medicines (Glycyrrhiza uralensis, G. glabra and G. inflata), market products and artificially interspecific hybrid forms of licorice. For this purpose, previous studies were investigated and visual and histological observations were carried out. We focused on the internal morphology by microscopic observation for securing objectivity. Finally, we proposed the identification keys for precise classification of each part. Results : 1) Original plant : Licorice species in the compendium were distinguished by the number of leaflets, presence of hair on the fruit, curvature and swelling of the fruit. 2) External morphology : Licorice species were distinguished by degree of powderiness, tearing gap, radial structure in the cross section and existence of protrusion of outer epidermis. 3) Internal morphology : Licorice species were distinguished by the degree of development of phloem fiber bundle, development of obliterated sieve, whether the secondary medullary ray are branched. In the case of interspecific hybrids, the characteristics of both species used for hybridization were mixed in all observation methods. Conclusions : These results suggest that the interspecific crossbred licorice is suitable for the pharmacopoeial standard. Therefore, it can be applied as a herbal medicine through additional supplementary study.","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"40 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77239111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/KJH.2019.34.6.131
Rodae Bang, Y. J. Lee
{"title":"A Review on Phytochemistry and Pharmacology of Sparassis crispa","authors":"Rodae Bang, Y. J. Lee","doi":"10.6116/KJH.2019.34.6.131","DOIUrl":"https://doi.org/10.6116/KJH.2019.34.6.131","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"13 1","pages":"131-138"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77358440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/kjh.2019.34.1.43
K. Rak
{"title":"Proofreading of one Ryang based on the Ratio of Maximum and Minimum Dose in the Decoction of ≪Treatise on Cold Damage Diseases≫","authors":"K. Rak","doi":"10.6116/kjh.2019.34.1.43","DOIUrl":"https://doi.org/10.6116/kjh.2019.34.1.43","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"15 1","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87758811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/KJH.2019.34.1.81
전의상, Jong-Gil Jeong, 이숭인
{"title":"A Herbological Study on the Plants of Verbenaceae in Korea","authors":"전의상, Jong-Gil Jeong, 이숭인","doi":"10.6116/KJH.2019.34.1.81","DOIUrl":"https://doi.org/10.6116/KJH.2019.34.1.81","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"28 1","pages":"81-90"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85117137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/KJH.2019.34.4.19
Choi-deokgyun, Chanik Park, Sun‐mi Lee, Jeong‐In Baek
{"title":"Anti-Melanogenic Effect of Thymol, a Major Odorant in Essential Oilsof Family Lamiaceae","authors":"Choi-deokgyun, Chanik Park, Sun‐mi Lee, Jeong‐In Baek","doi":"10.6116/KJH.2019.34.4.19","DOIUrl":"https://doi.org/10.6116/KJH.2019.34.4.19","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"1 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75504022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.6116/kjh.2019.34.2.49
Ouyang Fang-lan, Bu-Il Seo
{"title":"Anti-obesity effect of Cynanchi Wilfordii Radix on High fat diet-induced obese mice","authors":"Ouyang Fang-lan, Bu-Il Seo","doi":"10.6116/kjh.2019.34.2.49","DOIUrl":"https://doi.org/10.6116/kjh.2019.34.2.49","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"8 1","pages":"49-58"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77789150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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