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Correlation between Serum Fructosamine Level and Severity of Coronary Artery Disease in Diabetic Patients with Symptomatic Chronic Coronary Syndrome 糖尿病合并症状性慢性冠脉综合征患者血清果糖胺水平与冠脉病变严重程度的相关性
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318549
TAREK Kh. ABD EL DAYEM, M.D. ASMAA M.F. BEKHIT, M.Sc.; MOHAMED
Background: In patients with diabetes mellitus (DM), compared with those without DM, (CAD) tends to be more diffuse, complex, and associated with increased morbidity and mortality from cardiovascular disease. The SYNTAX score (SS) uses coronary anatomy to objectively guide decisions regarding mode of revascularization. It characterizes the extent of coronary disease in terms of the number of lesions, their functional importance, and their complexity, while GENSINI Score accounts for the degree of artery disease in diabetic patients. Aim of Study: The aim of this study was to assess the correlation between fructosamine level and the severity of CAD by calculating SYNTAX and GENSINI scores in diabetic patients presenting to Ain Shams University Hospital with symptomatic chronic coronary syndrome undergoing elective coronary angiography. Patient and Methods: This study was conducted on 200 diabetic patients with chronic coronary syndrome undergoing elective coronary angiography, with mean age 54.36±5.86 years ranging from 32 years to 65 years. The majority of them were males (64%). Results: Atotal of 200 diabetic patients were included in the study. Mean ± SD age was 54.36±5.86 years. Of the total 64% (128) were males, 74% (149) were hypertensive and 57% (113) were smokers.We found that higher fructosamine level was strongly correlated with disease severity and higher SYNTAXas well as GENSINI score as fructosamine and SYNTAX score ( r =0.668) and with GENSINI ( r =0.734) ( p - values <0.001 and <0.001 respectively). A significant increase in fructosamine level was notedin higher tertiles of SYNTAX and GENSINI scores ( p -values <0.001 and <0.001 respectively). There was also a positive correlation between both HbA1c and SYNTAX score ( r =0.636) and with GENSINI score ( r =0.716). Conclusion: There was a significant correlation between serum fructosamine level and severity of CAD assessed by the angiographically derived SYNTAX and GENSINI scores
{"title":"Correlation between Serum Fructosamine Level and Severity of Coronary Artery Disease in Diabetic Patients with Symptomatic Chronic Coronary Syndrome","authors":"TAREK Kh. ABD EL DAYEM, M.D. ASMAA M.F. BEKHIT, M.Sc.; MOHAMED","doi":"10.21608/mjcu.2023.318549","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318549","url":null,"abstract":"Background: In patients with diabetes mellitus (DM), compared with those without DM, (CAD) tends to be more diffuse, complex, and associated with increased morbidity and mortality from cardiovascular disease. The SYNTAX score (SS) uses coronary anatomy to objectively guide decisions regarding mode of revascularization. It characterizes the extent of coronary disease in terms of the number of lesions, their functional importance, and their complexity, while GENSINI Score accounts for the degree of artery disease in diabetic patients. Aim of Study: The aim of this study was to assess the correlation between fructosamine level and the severity of CAD by calculating SYNTAX and GENSINI scores in diabetic patients presenting to Ain Shams University Hospital with symptomatic chronic coronary syndrome undergoing elective coronary angiography. Patient and Methods: This study was conducted on 200 diabetic patients with chronic coronary syndrome undergoing elective coronary angiography, with mean age 54.36±5.86 years ranging from 32 years to 65 years. The majority of them were males (64%). Results: Atotal of 200 diabetic patients were included in the study. Mean ± SD age was 54.36±5.86 years. Of the total 64% (128) were males, 74% (149) were hypertensive and 57% (113) were smokers.We found that higher fructosamine level was strongly correlated with disease severity and higher SYNTAXas well as GENSINI score as fructosamine and SYNTAX score ( r =0.668) and with GENSINI ( r =0.734) ( p - values <0.001 and <0.001 respectively). A significant increase in fructosamine level was notedin higher tertiles of SYNTAX and GENSINI scores ( p -values <0.001 and <0.001 respectively). There was also a positive correlation between both HbA1c and SYNTAX score ( r =0.636) and with GENSINI score ( r =0.716). Conclusion: There was a significant correlation between serum fructosamine level and severity of CAD assessed by the angiographically derived SYNTAX and GENSINI scores","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Vaccines in a Cohort of Egyptian Patients with Auto-Immune Rheumatic Diseases COVID-19疫苗在埃及自身免疫性风湿病患者队列中的应用
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318260
SALLY S. MOHAMED, M.D.* KAMAL EL-GARF, M.D.*; HEND H. TAMIM,
.
{"title":"COVID-19 Vaccines in a Cohort of Egyptian Patients with Auto-Immune Rheumatic Diseases","authors":"SALLY S. MOHAMED, M.D.* KAMAL EL-GARF, M.D.*; HEND H. TAMIM,","doi":"10.21608/mjcu.2023.318260","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318260","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes in Elderly Patients with Mechanical Aortic Valve Replacement: Systematic Review and Meta-Analysis 老年机械主动脉瓣置换术患者的预后:系统回顾和meta分析
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318269
MOHAMED T. ELSAYEGH, M.D. MOHAMED ABDELMOTTAAL TAWAB, M.Sc.;
.
{"title":"Outcomes in Elderly Patients with Mechanical Aortic Valve Replacement: Systematic Review and Meta-Analysis","authors":"MOHAMED T. ELSAYEGH, M.D. MOHAMED ABDELMOTTAAL TAWAB, M.Sc.;","doi":"10.21608/mjcu.2023.318269","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318269","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dexmedetomidine Added to Bupivacaine Versus Bupivacaine Alone in Ultrasound-Guided Erector Spinae Block in Spine Surgeries for Post Operative Pain Management: A Randomized Controlled Study 右美托咪定加布比卡因与单独布比卡因在超声引导下脊柱手术后疼痛管理中的直立脊柱阻滞:一项随机对照研究
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318546
ASMAA A. YOUSSEF MOHAMED, M.Sc.** MANAR M. ELKHOLY, M.D.*; AHMED
.
{"title":"Dexmedetomidine Added to Bupivacaine Versus Bupivacaine Alone in Ultrasound-Guided Erector Spinae Block in Spine Surgeries for Post Operative Pain Management: A Randomized Controlled Study","authors":"ASMAA A. YOUSSEF MOHAMED, M.Sc.** MANAR M. ELKHOLY, M.D.*; AHMED","doi":"10.21608/mjcu.2023.318546","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318546","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Predictors of Atrial High Rate Episodes in Patients with Cardiac Implantable Electronic Devices 心脏植入式电子装置患者心房高率发作的患病率及预测因素
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318548
TAREK A. ABDEL FATTAH, M.D. AMIRA M. AL-AWADY RIZK, M.Sc.;
.
{"title":"Prevalence and Predictors of Atrial High Rate Episodes in Patients with Cardiac Implantable Electronic Devices","authors":"TAREK A. ABDEL FATTAH, M.D. AMIRA M. AL-AWADY RIZK, M.Sc.;","doi":"10.21608/mjcu.2023.318548","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318548","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis of Different Spinal Lesions by Multi Parametric MRI 不同脊柱病变的多参数MRI诊断
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318276
ASMAA H. ABDELAZIZ AHMED, M.Sc.* AHMED EL-MORSY, M.D.*; BASEM IBRAHIM
.
{"title":"Diagnosis of Different Spinal Lesions by Multi Parametric MRI","authors":"ASMAA H. ABDELAZIZ AHMED, M.Sc.* AHMED EL-MORSY, M.D.*; BASEM IBRAHIM","doi":"10.21608/mjcu.2023.318276","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318276","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Laparoscopy in Diagnosis and Management of Acute Abdomen 腹腔镜在急腹症诊断和治疗中的作用
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318289
ALI M.S. SOKER, M.Sc. ASHRAF F. ABADEER, M.D.; AMR M.M.
.
{"title":"Role of Laparoscopy in Diagnosis and Management of Acute Abdomen","authors":"ALI M.S. SOKER, M.Sc. ASHRAF F. ABADEER, M.D.; AMR M.M.","doi":"10.21608/mjcu.2023.318289","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318289","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Gamma Glutamyl Transferase in the Diagnosis of Common Bile Duct Stones 谷氨酰基转移酶在胆总管结石诊断中的作用
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318272
MOHAMMED M.I.M. ORZ, M.Sc. MOHAMED M. BAHAA ELDIN, M.D.; MOHAMED
.
{"title":"Role of Gamma Glutamyl Transferase in the Diagnosis of Common Bile Duct Stones","authors":"MOHAMMED M.I.M. ORZ, M.Sc. MOHAMED M. BAHAA ELDIN, M.D.; MOHAMED","doi":"10.21608/mjcu.2023.318272","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318272","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maximal Beneficials Foreshows of Adopting De Vega Annuloplasy Technique Addressing Secondary Severe Tricuspid Regurgitation 采用De Vega环成形术治疗继发性严重三尖瓣反流的最大获益展望
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318271
AHMED T. ELGENGEHE, M.D.** AHMED SABER, M.D., F.R.C.S. (Glasg)*
Background: Persistence of significant secondary tricuspid regurgitation (TR) after its repair concomitant with a left-sided valve replacement contributes to increased mortality and morbidity in the immediate and late postoperative periods. Thus, attention is paid to trace risk factors that might affect the success of the repair. However, the knowledge of the exact underlying risk factors and relevant mechanisms contributing to progression of secondary TR is less. Aim of Study: This study aims at identifying the effectiveness of adopting De Vega annuloplasty technique in dealing with cases of secondary severe TR in decreasing or abolishing it (over one year follow-up period) and evaluating the possible risk factors of failure of repair as well. As such, the purpose of addressing agents favoring the best accepted results of the nominated maneuver and planning the optimal surgical method of such secondary TR could be achieved. Patients and Methods: This retrospective observational non-randomized study included 31 patients who had repair of the tricuspid valve (TV) by De Vega annuloplasty technique. They presented with either mitral valve disease and associated secondary severe TR (double valve disease) or combined mitral and aortic valves disease and associated secondary severe TR (triple valve disease). They had been operated upon be either mitral valve replacement (MVR) and De Vega annuloplasty for the TV or combined MVR and aortic valve replacement (AVR) i.e., double valve replacement (DVR) and De Vega annuloplasty for the TV. Postoperative mortality, morbidity outcomes, overall hospital complications, left ventricular ejection fraction (LVEF%), TR degree, functional clinical status, predictorsof failure of TV repair and overall one-year survival were evaluated. Results: Mean age was 37.25±7.31 years. The overall hospital complication rate was 25.80%. No mortality happened during the follow-up period (overall one-year survival rate was 100%). The cumulative duration of the study was 3.167 years. Significant improvement in the degree of TR, New Yok Heart Association (NYHA) classification and LVEF% was observed. Identified risk factors that were found to be statistically significant predictors of progression of the secondary
{"title":"Maximal Beneficials Foreshows of Adopting De Vega Annuloplasy Technique Addressing Secondary Severe Tricuspid Regurgitation","authors":"AHMED T. ELGENGEHE, M.D.** AHMED SABER, M.D., F.R.C.S. (Glasg)*","doi":"10.21608/mjcu.2023.318271","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318271","url":null,"abstract":"Background: Persistence of significant secondary tricuspid regurgitation (TR) after its repair concomitant with a left-sided valve replacement contributes to increased mortality and morbidity in the immediate and late postoperative periods. Thus, attention is paid to trace risk factors that might affect the success of the repair. However, the knowledge of the exact underlying risk factors and relevant mechanisms contributing to progression of secondary TR is less. Aim of Study: This study aims at identifying the effectiveness of adopting De Vega annuloplasty technique in dealing with cases of secondary severe TR in decreasing or abolishing it (over one year follow-up period) and evaluating the possible risk factors of failure of repair as well. As such, the purpose of addressing agents favoring the best accepted results of the nominated maneuver and planning the optimal surgical method of such secondary TR could be achieved. Patients and Methods: This retrospective observational non-randomized study included 31 patients who had repair of the tricuspid valve (TV) by De Vega annuloplasty technique. They presented with either mitral valve disease and associated secondary severe TR (double valve disease) or combined mitral and aortic valves disease and associated secondary severe TR (triple valve disease). They had been operated upon be either mitral valve replacement (MVR) and De Vega annuloplasty for the TV or combined MVR and aortic valve replacement (AVR) i.e., double valve replacement (DVR) and De Vega annuloplasty for the TV. Postoperative mortality, morbidity outcomes, overall hospital complications, left ventricular ejection fraction (LVEF%), TR degree, functional clinical status, predictorsof failure of TV repair and overall one-year survival were evaluated. Results: Mean age was 37.25±7.31 years. The overall hospital complication rate was 25.80%. No mortality happened during the follow-up period (overall one-year survival rate was 100%). The cumulative duration of the study was 3.167 years. Significant improvement in the degree of TR, New Yok Heart Association (NYHA) classification and LVEF% was observed. Identified risk factors that were found to be statistically significant predictors of progression of the secondary","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response of Pulmonary Functions to Inspiratory Muscles Training Versus Pneumatic Compression in COPD Patients COPD患者肺功能对吸气肌训练与气压压缩的反应
Pub Date : 2023-06-01 DOI: 10.21608/mjcu.2023.318244
ALI M.A. ISMAIL, Ph.D.* HEBA G.A. ELDAOUS, M.Sc.*; NAGWA
.
{"title":"Response of Pulmonary Functions to Inspiratory Muscles Training Versus Pneumatic Compression in COPD Patients","authors":"ALI M.A. ISMAIL, Ph.D.* HEBA G.A. ELDAOUS, M.Sc.*; NAGWA","doi":"10.21608/mjcu.2023.318244","DOIUrl":"https://doi.org/10.21608/mjcu.2023.318244","url":null,"abstract":".","PeriodicalId":22964,"journal":{"name":"The Medical Journal of Cairo University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135143420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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The Medical Journal of Cairo University
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