首页 > 最新文献

The professional medical journal最新文献

英文 中文
Impact of smartphone usage on academic performance of undergraduate medical college. 使用智能手机对医学院本科生学习成绩的影响。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7860
M. Iqbal, Minahil Shafique, Aqsa Afzal, Fizza Noor, Muhammad Waseem, Unsa Marrium
Objective: To assess the effect of smartphone usage on the academic performance of the students of Sahiwal Medical College. Study Design: Cross-sectional study. Setting: Department of Physiology, Sahiwal Medical College, Sahiwal. Period: 24th May to 25th July 2022. Material & Methods: and a validated questionnaire was shared among the 114 undergraduate students of 1st and 2nd year MBBS of Sahiwal Medical College. Results: Our study involved 114 participants of age between 18-20 years. The majority of the participants were females (78.4%) and the duration of smartphone usage of most students was between two to six hours per day (66.7%). No statistical significance was found between the usage of smartphones and the academic performance of students. Conclusion: There is no association between smartphone usage and the academic performance of undergraduate medical students.
目的评估智能手机的使用对萨希瓦尔医学院学生学习成绩的影响。研究设计:横断面研究。研究地点萨希瓦尔医学院生理学系。时间:2022 年 5 月 24 日至 7 月 25 日。材料与方法:向萨希瓦尔医学院医学学士学位一年级和二年级的 114 名本科生发放有效问卷。结果:我们的研究涉及 114 名年龄在 18-20 岁之间的参与者。大多数参与者为女性(78.4%),大多数学生每天使用智能手机的时间为 2 至 6 小时(66.7%)。使用智能手机与学生的学习成绩之间没有统计学意义。结论医科本科生使用智能手机与学习成绩之间没有关联。
{"title":"Impact of smartphone usage on academic performance of undergraduate medical college.","authors":"M. Iqbal, Minahil Shafique, Aqsa Afzal, Fizza Noor, Muhammad Waseem, Unsa Marrium","doi":"10.29309/tpmj/2024.31.03.7860","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7860","url":null,"abstract":"Objective: To assess the effect of smartphone usage on the academic performance of the students of Sahiwal Medical College. Study Design: Cross-sectional study. Setting: Department of Physiology, Sahiwal Medical College, Sahiwal. Period: 24th May to 25th July 2022. Material & Methods: and a validated questionnaire was shared among the 114 undergraduate students of 1st and 2nd year MBBS of Sahiwal Medical College. Results: Our study involved 114 participants of age between 18-20 years. The majority of the participants were females (78.4%) and the duration of smartphone usage of most students was between two to six hours per day (66.7%). No statistical significance was found between the usage of smartphones and the academic performance of students. Conclusion: There is no association between smartphone usage and the academic performance of undergraduate medical students.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"98 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High fluorescent lymphocytes in dengue infection; A navigator for hematopathologists. 登革热感染中的高荧光淋巴细胞;血液病理学家的导航仪。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7965
Fariha Nasreen, Attika Khalid, M. Rehan, Asma Shaikh, Humaira Rehman
Objective: The aim of this research is the early detection of dengue infection on the basis of presence of high fluorescent lymphocyte (HFL) which enables the clinicians to tailor further investigations and early commencement of treatment to prevent complications and thus can reduce mortality and morbidity in dengue patients. Study Design: Prospective Research. Setting: Fauji Foundation Hospital in Rawalpindi. Period: February 2022 to July 2022. Material & Methods: Samples of Full blood counts (FBC) received in Pathology laboratory were processed on automated Hematology analyzer Sysmex XN-series (XN-1000). All the FBCs that were of known dengue patients were excluded from the study. The FBCs with High Fluorescent Lymphocytes on White blood cell differential fluorescence (WDF) scattergram were selected and evaluated. Detection of dengue infection was done by using Dengue Virus ELISA (IgM and IgG) test. Results: Among one hundred samples with High Fluorescence Lymphocyte there were 77% were Dengue Positive. Binomial test did give a significant association of Dengue with High Fluorescence Lymphocyte (p<0.01). Conclusion: We draw the conclusion that presence of high fluorescent lymphocytes helps in the early detection of dengue positive cases.
研究目的这项研究的目的是根据高荧光淋巴细胞(HFL)的存在情况及早发现登革热感染,从而使临床医生能够有针对性地进行进一步检查并及早开始治疗,预防并发症的发生,从而降低登革热患者的死亡率和发病率。研究设计:前瞻性研究。研究地点拉瓦尔品第的 Fauji 基金会医院。时间: 2022 年 2 月至 2022 年 7 月2022 年 2 月至 2022 年 7 月。材料与方法:病理实验室收到的全血细胞计数(FBC)样本在自动血液分析仪 Sysmex XN-系列(XN-1000)上进行处理。所有已知登革热病人的全血细胞计数样本均排除在研究之外。选择并评估白细胞差异荧光散点图(WDF)上有高荧光淋巴细胞的 FBC。登革热病毒酶联免疫吸附试验(IgM 和 IgG)检测登革热感染。结果在 100 个高荧光淋巴细胞样本中,77% 呈登革热阳性。二项式检验结果表明登革热与高荧光淋巴细胞有明显关联(P<0.01)。结论我们得出的结论是,高荧光淋巴细胞的存在有助于早期发现登革热阳性病例。
{"title":"High fluorescent lymphocytes in dengue infection; A navigator for hematopathologists.","authors":"Fariha Nasreen, Attika Khalid, M. Rehan, Asma Shaikh, Humaira Rehman","doi":"10.29309/tpmj/2024.31.03.7965","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7965","url":null,"abstract":"Objective: The aim of this research is the early detection of dengue infection on the basis of presence of high fluorescent lymphocyte (HFL) which enables the clinicians to tailor further investigations and early commencement of treatment to prevent complications and thus can reduce mortality and morbidity in dengue patients. Study Design: Prospective Research. Setting: Fauji Foundation Hospital in Rawalpindi. Period: February 2022 to July 2022. Material & Methods: Samples of Full blood counts (FBC) received in Pathology laboratory were processed on automated Hematology analyzer Sysmex XN-series (XN-1000). All the FBCs that were of known dengue patients were excluded from the study. The FBCs with High Fluorescent Lymphocytes on White blood cell differential fluorescence (WDF) scattergram were selected and evaluated. Detection of dengue infection was done by using Dengue Virus ELISA (IgM and IgG) test. Results: Among one hundred samples with High Fluorescence Lymphocyte there were 77% were Dengue Positive. Binomial test did give a significant association of Dengue with High Fluorescence Lymphocyte (p<0.01). Conclusion: We draw the conclusion that presence of high fluorescent lymphocytes helps in the early detection of dengue positive cases.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"163 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140265377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of diffusion weighted imaging on MRI in suspected cases of ovarian cancer, keeping histopathology as gold standard. 以组织病理学为金标准,磁共振成像弥散加权成像对疑似卵巢癌病例的诊断准确性。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7953
Maryam Latif, Salahuddin Balooch, Zeeshan Ali, Umar Amin, Kiran Zafar, Muhammad Usman Khan
Objective: To assess the diagnostic accuracy of diffusion weighted imaging on MRI in patients of ovarian cancer with histopathology considered as gold standard. Study Design: Cross-sectional study. Setting: Department of Radiology, Tertiary Care Hospital Kharian. Period: February 2022 to August 2022. Material & Methods: Non-probability, consecutive sampling was performed from 60 patients. After receiving informed consents, the suspected female patients with age 15 to 65 years went under MRI. The results were compared with histopathological findings and diagnostic potential of MRI was calculated by 2x2 table. The findings of both the modalities were compared by correlation analysis with p<0.05 considered as significant. Results: The sensitivity and specificity of MRI were estimated to be 92.68% and 73.68%. The positive predictive value and negative predictive value were estimated to be 88.37% and 82.35%. The diagnostic accuracy was found to be 86.66%. The findings of MRI and histopathology were significantly (p<0.05) correlated with a value of 0.685. Conclusion: The use of MRI is highly recommended in diagnosis of ovarian cancer.
目的评估以组织病理学为金标准的磁共振成像弥散加权成像对卵巢癌患者的诊断准确性。研究设计:横断面研究。研究地点哈里安三级医院放射科。时间: 2022年2月至2022年8月2022 年 2 月至 2022 年 8 月。材料与方法:从 60 名患者中进行非概率连续抽样。在获得知情同意后,对 15 至 65 岁的疑似女性患者进行核磁共振成像检查。结果与组织病理学结果进行比较,并通过 2x2 表计算核磁共振成像的诊断潜力。两种方法的结果通过相关性分析进行比较,P<0.05 为差异显著。结果:核磁共振成像的敏感性和特异性分别为 92.68% 和 73.68%。阳性预测值和阴性预测值分别为 88.37% 和 82.35%。诊断准确率为 86.66%。核磁共振成像结果与组织病理学结果呈显著相关(P<0.05),相关值为 0.685。结论:强烈建议在诊断卵巢癌时使用磁共振成像。
{"title":"Diagnostic accuracy of diffusion weighted imaging on MRI in suspected cases of ovarian cancer, keeping histopathology as gold standard.","authors":"Maryam Latif, Salahuddin Balooch, Zeeshan Ali, Umar Amin, Kiran Zafar, Muhammad Usman Khan","doi":"10.29309/tpmj/2024.31.03.7953","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7953","url":null,"abstract":"Objective: To assess the diagnostic accuracy of diffusion weighted imaging on MRI in patients of ovarian cancer with histopathology considered as gold standard. Study Design: Cross-sectional study. Setting: Department of Radiology, Tertiary Care Hospital Kharian. Period: February 2022 to August 2022. Material & Methods: Non-probability, consecutive sampling was performed from 60 patients. After receiving informed consents, the suspected female patients with age 15 to 65 years went under MRI. The results were compared with histopathological findings and diagnostic potential of MRI was calculated by 2x2 table. The findings of both the modalities were compared by correlation analysis with p<0.05 considered as significant. Results: The sensitivity and specificity of MRI were estimated to be 92.68% and 73.68%. The positive predictive value and negative predictive value were estimated to be 88.37% and 82.35%. The diagnostic accuracy was found to be 86.66%. The findings of MRI and histopathology were significantly (p<0.05) correlated with a value of 0.685. Conclusion: The use of MRI is highly recommended in diagnosis of ovarian cancer.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"77 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140080309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of computed tomography brain perfusion in the prediction of acute ischemic stroke taking the findings of MRI as gold standard. 以核磁共振成像结果为金标准,计算机断层扫描脑灌注在预测急性缺血性中风方面的诊断准确性。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7957
Bushra Ujala, Nosheen Ahmad, Arwa Naeem
Objectives: To determine the diagnostic accuracy of computed tomography brain perfusion to predict acute ischemic stroke taking the findings of MRI as gold standard. Study Design: Cross-sectional Validation study. Setting: Department of Radiology Allied Hospital Faisalabad. Period: 20th May 2022 to 19th November 2022. Material & Methods: A total of 215 individuals, aged between 30 and 70, of both sexes, and exhibiting ischemic stroke symptoms lasting no more than 12 hours, were included. Patients with abnormal renal function tests having renal disease were excluded. The conventional non-contrast CT used in the CT stroke protocol had basal sections that were either 3 mm or 4 mm in thickness and supra tentorial sections that were either 3 mm or 4 mm in thickness. The acquisition parameters were 80kVp and 120mAs. Dynamic CT perfusion was carried out with 4 cm plane coverage. At the seventh day, all patients underwent a follow-up MRI using a 1.5 Tesla Philips MRI scanner. A radiologist examined CTP to look for signs of early ischemic changes. For CT perfusion (CTP), measurements were taken for time to peak (TTP), cerebral blood flow (CBF), and cerebral blood volume (CBV). Results: Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of computed tomography brain perfusion in the prediction of acute ischemic stroke taking the findings of MRI as gold standard was 85.37%, 76.09%, 82.68%, 79.55% and 81.40% respectively. Conclusion: This study led to the conclusion that diagnostic accuracy of computed tomography brain perfusion to predict acute ischemic stroke is quite high.
目的以核磁共振成像结果为金标准,确定计算机断层扫描脑灌注预测急性缺血性中风的诊断准确性。研究设计:横断面验证研究。研究地点费萨拉巴德联合医院放射科。时间:2022 年 5 月 20 日至 2022 年 11 月 19 日。材料与方法共纳入 215 名年龄在 30 岁至 70 岁之间、表现出缺血性中风症状且持续时间不超过 12 小时的男女患者。排除肾功能检查异常的肾病患者。中风 CT 方案中使用的常规非对比 CT 的基底切片厚度为 3 毫米或 4 毫米,触角上切片厚度为 3 毫米或 4 毫米。采集参数为 80kVp 和 120mAs。动态 CT 灌注的平面覆盖范围为 4 厘米。第七天,所有患者都使用 1.5 特斯拉飞利浦核磁共振扫描仪进行了核磁共振随访。放射科医生检查了 CTP,以寻找早期缺血性变化的迹象。对于 CT 灌注 (CTP),则测量峰值时间 (TTP)、脑血流量 (CBF) 和脑血容量 (CBV)。结果以核磁共振成像结果为金标准,计算机断层扫描脑灌注预测急性缺血性中风的总体敏感性、特异性、阳性预测值、阴性预测值和诊断准确性分别为 85.37%、76.09%、82.68%、79.55% 和 81.40%。结论本研究得出结论,计算机断层扫描脑灌注预测急性缺血性中风的诊断准确率相当高。
{"title":"Diagnostic accuracy of computed tomography brain perfusion in the prediction of acute ischemic stroke taking the findings of MRI as gold standard.","authors":"Bushra Ujala, Nosheen Ahmad, Arwa Naeem","doi":"10.29309/tpmj/2024.31.03.7957","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7957","url":null,"abstract":"Objectives: To determine the diagnostic accuracy of computed tomography brain perfusion to predict acute ischemic stroke taking the findings of MRI as gold standard. Study Design: Cross-sectional Validation study. Setting: Department of Radiology Allied Hospital Faisalabad. Period: 20th May 2022 to 19th November 2022. Material & Methods: A total of 215 individuals, aged between 30 and 70, of both sexes, and exhibiting ischemic stroke symptoms lasting no more than 12 hours, were included. Patients with abnormal renal function tests having renal disease were excluded. The conventional non-contrast CT used in the CT stroke protocol had basal sections that were either 3 mm or 4 mm in thickness and supra tentorial sections that were either 3 mm or 4 mm in thickness. The acquisition parameters were 80kVp and 120mAs. Dynamic CT perfusion was carried out with 4 cm plane coverage. At the seventh day, all patients underwent a follow-up MRI using a 1.5 Tesla Philips MRI scanner. A radiologist examined CTP to look for signs of early ischemic changes. For CT perfusion (CTP), measurements were taken for time to peak (TTP), cerebral blood flow (CBF), and cerebral blood volume (CBV). Results: Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of computed tomography brain perfusion in the prediction of acute ischemic stroke taking the findings of MRI as gold standard was 85.37%, 76.09%, 82.68%, 79.55% and 81.40% respectively. Conclusion: This study led to the conclusion that diagnostic accuracy of computed tomography brain perfusion to predict acute ischemic stroke is quite high.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"48 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140080605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of prolonged colonoscopy and its associated factors among adults: An experience of A Tertiary Care Hospital in Karachi, Pakistan. 成人长时间结肠镜检查的频率及其相关因素:巴基斯坦卡拉奇一家三级医院的经验。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.8016
Mashal Bai, Shahid Karim, Rajesh Kumar, Sindhu Rani, A. Faryal
Objective: To determine frequency and factors associated with prolong cecal intubation among adults undergoing colonoscopy in a tertiary care hospital. Study Design: Cross-sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan. Period: September 2022 to June 2023. Material & Methods: The study comprised patients undergoing elective colonoscopies, regardless of gender and age, who were at least eighteen years old. Cecal intubation time longer than ten minutes was regarded as a prolonged colonoscopy duration. The Aronchick scale, which is used to evaluate the quality of bowel preparation. The association between the patient's characteristics and the prolonged cecal intubation was investigated using logistic regression. P-values were considered statistically significant if they were less than or equal to 0.05. Results: Total 281 patients were enrolled into the study. Median age of patients was 40 (IQR=30-50) years and majority were males 66.5%. Median cecal intubation length and time was 90 (IQR=80-100) cm and 7 (IQR=5-10) minutes. Prolonged intubation was seen among nearly one-fifth of total patients (19.1%). Odds of prolonged cecal intubation were significantly lower patients of age <50 years, relatively higher body mass index (BMI), out-patients, patients with excellent quality of bowel preparation and among those cases in which colonoscopies were performed by consultant. Conclusion: Proportion of prolonged cecal intubation was high particularly among older age, female gender, patients with lower BMI, past surgeries and poor quality of bowel preparation.
目的确定在一家三甲医院接受结肠镜检查的成人中延长盲肠插管的频率和相关因素。研究设计:横断面研究。研究地点巴基斯坦卡拉奇利亚卡特国立医院消化内科。时间: 2022 年 9 月至 2023 年 6 月2022 年 9 月至 2023 年 6 月。材料与方法:研究对象为接受择期结肠镜检查的患者,不分性别和年龄,至少年满十八岁。盲肠插管时间超过十分钟被视为结肠镜检查时间过长。Aronchick 量表用于评估肠道准备工作的质量。采用逻辑回归法研究了患者特征与盲肠插管时间延长之间的关系。如果 P 值小于或等于 0.05,则认为具有统计学意义。结果共有 281 名患者参与研究。患者的中位年龄为 40 岁(IQR=30-50),男性占 66.5%。中位盲肠插管长度和时间分别为 90 厘米(IQR=80-100)和 7 分钟(IQR=5-10)。近五分之一的患者(19.1%)插管时间过长。年龄小于 50 岁、体重指数(BMI)相对较高、门诊患者、肠道准备质量良好的患者以及由顾问进行结肠镜检查的病例中,盲肠插管时间延长的几率明显较低。结论在年龄较大、性别为女性、体重指数较低、既往接受过手术和肠道准备质量较差的患者中,长时间盲肠插管的比例较高。
{"title":"Frequency of prolonged colonoscopy and its associated factors among adults: An experience of A Tertiary Care Hospital in Karachi, Pakistan.","authors":"Mashal Bai, Shahid Karim, Rajesh Kumar, Sindhu Rani, A. Faryal","doi":"10.29309/tpmj/2024.31.03.8016","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.8016","url":null,"abstract":"Objective: To determine frequency and factors associated with prolong cecal intubation among adults undergoing colonoscopy in a tertiary care hospital. Study Design: Cross-sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan. Period: September 2022 to June 2023. Material & Methods: The study comprised patients undergoing elective colonoscopies, regardless of gender and age, who were at least eighteen years old. Cecal intubation time longer than ten minutes was regarded as a prolonged colonoscopy duration. The Aronchick scale, which is used to evaluate the quality of bowel preparation. The association between the patient's characteristics and the prolonged cecal intubation was investigated using logistic regression. P-values were considered statistically significant if they were less than or equal to 0.05. Results: Total 281 patients were enrolled into the study. Median age of patients was 40 (IQR=30-50) years and majority were males 66.5%. Median cecal intubation length and time was 90 (IQR=80-100) cm and 7 (IQR=5-10) minutes. Prolonged intubation was seen among nearly one-fifth of total patients (19.1%). Odds of prolonged cecal intubation were significantly lower patients of age <50 years, relatively higher body mass index (BMI), out-patients, patients with excellent quality of bowel preparation and among those cases in which colonoscopies were performed by consultant. Conclusion: Proportion of prolonged cecal intubation was high particularly among older age, female gender, patients with lower BMI, past surgeries and poor quality of bowel preparation.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"19 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-ionic contrast material in pediatric ct scans: A statistical analysis of mild allergic reactions. 儿科 CT 扫描中的非离子造影剂:轻度过敏反应统计分析
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7571
Abdul Maajid Khokhar
Objective: To assess allergic reactions to IV non-ionic contrast media in children. Study Design: Cross-sectional study. Setting: Faisal Hospital, Faisalabad, and Children Hospital, Faisalabad. Period: June 2022 to September 2022. Material & Methods: A total of 310 patients (males and females) under the age of 14, referred for a CT scan with non-ionic contrast material were included in the study, Data were collected at the Children’s Hospital and the Faisal Hospital Faisalabad for over 4 months and statistically analyzed by SPSS V22. The Chi-square test was used to measure the association between the age of children and mild allergy reactions. Results: This study included 310 patients, 183 (59%) males, and 127 (41%) females, who received the non-ionic contrast agent. Thirteen patients (6 males and 7 females) experienced mild allergic responses including 5 cases of rash, 3 cases of itching, 2 cases of nausea, and 1 case of vomiting, flushing, and swelling. There were 10 reactions for children under five, 1 for children between five to ten years, and 2 for children older than ten years. Out of 13 reported allergic reactions, the brain region observed seven while the chest, head, and neck regions observed none. Conclusion: According to the findings of this study, imaging young children with low-osmolality non-ionic contrast material is relatively safe and has few side effects. Out of 310, only 13 children experienced mild allergic responses to non-ionic contrast material. This study found an association between the age of children (<5 years) and mild allergic reactions (skin rash and itching) which was found to be statistically significant (p=0.005).
目的:评估儿童对静脉注射非离子造影剂的过敏反应:评估儿童对静脉注射非离子造影剂的过敏反应。研究设计:横断面研究。研究地点:费萨拉巴德费萨尔医院和费萨拉巴德儿童医院费萨拉巴德费萨尔医院和费萨拉巴德儿童医院。时间: 2022 年 6 月至 2022 年 9 月2022 年 6 月至 2022 年 9 月。材料与方法:在费萨拉巴德费萨拉巴德儿童医院和费萨拉巴德费萨拉医院收集了超过 4 个月的数据,并使用 SPSS V22 进行了统计分析。研究采用卡方检验来衡量儿童年龄与轻度过敏反应之间的关系。结果:这项研究包括 310 名接受非离子造影剂治疗的患者,其中 183 名(59%)为男性,127 名(41%)为女性。有 13 名患者(6 名男性和 7 名女性)出现了轻度过敏反应,包括 5 例皮疹、3 例瘙痒、2 例恶心和 1 例呕吐、潮红和肿胀。五岁以下儿童有 10 例,五至十岁儿童有 1 例,十岁以上儿童有 2 例。在报告的 13 例过敏反应中,脑部有 7 例,而胸部、头部和颈部则没有。结论根据这项研究的结果,使用低渗透压非离子造影剂对幼儿进行造影相对安全,副作用较小。在 310 名儿童中,只有 13 名儿童对非离子造影剂有轻微过敏反应。这项研究发现,儿童的年龄(小于 5 岁)与轻度过敏反应(皮疹和瘙痒)之间存在关联,且具有统计学意义(P=0.005)。
{"title":"Non-ionic contrast material in pediatric ct scans: A statistical analysis of mild allergic reactions.","authors":"Abdul Maajid Khokhar","doi":"10.29309/tpmj/2024.31.03.7571","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7571","url":null,"abstract":"Objective: To assess allergic reactions to IV non-ionic contrast media in children. Study Design: Cross-sectional study. Setting: Faisal Hospital, Faisalabad, and Children Hospital, Faisalabad. Period: June 2022 to September 2022. Material & Methods: A total of 310 patients (males and females) under the age of 14, referred for a CT scan with non-ionic contrast material were included in the study, Data were collected at the Children’s Hospital and the Faisal Hospital Faisalabad for over 4 months and statistically analyzed by SPSS V22. The Chi-square test was used to measure the association between the age of children and mild allergy reactions. Results: This study included 310 patients, 183 (59%) males, and 127 (41%) females, who received the non-ionic contrast agent. Thirteen patients (6 males and 7 females) experienced mild allergic responses including 5 cases of rash, 3 cases of itching, 2 cases of nausea, and 1 case of vomiting, flushing, and swelling. There were 10 reactions for children under five, 1 for children between five to ten years, and 2 for children older than ten years. Out of 13 reported allergic reactions, the brain region observed seven while the chest, head, and neck regions observed none. Conclusion: According to the findings of this study, imaging young children with low-osmolality non-ionic contrast material is relatively safe and has few side effects. Out of 310, only 13 children experienced mild allergic responses to non-ionic contrast material. This study found an association between the age of children (<5 years) and mild allergic reactions (skin rash and itching) which was found to be statistically significant (p=0.005).","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"20 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of microscopic colitis in patients presenting with chronic diarrhea. 慢性腹泻患者患显微镜下结肠炎的频率。
Pub Date : 2024-03-04 DOI: 10.29309/tpmj/2024.31.03.7757
Naik Muhammad, Mansoor-Ul-Haq, Adeel Rahat, Asad Abbas Jafri
Objective: To evaluate frequency of microscopic colitis in patients presenting with chronic diarrhea at a tertiary care hospital in Karachi, Pakistan. Study Design: Descriptive Cross-sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan. Period: January, 2022 to June, 2022. Material & Methods: Patients presenting in out-patient department of age >18 years of any gender with history of diarrhea >1 month, normal thyroid tests, negative serology for Celiac disease (Anti TTG IgA and IgG), and normal colonoscopy findings including terminal ileum were enrolled in the study after written informed consent. MC diagnosis was established using clinical diarrhea history and colonic biopsy findings. Results: Total 130 patients were analyzed with median age of 38 (IQR= 28-55) years. Nearly half were females (n=67, 51.5%). All patients had normal colonoscopy findings. Out of 130 patients, microscopic colitis was seen among 7(5.4%) cases out of which 5(3.8%) had lymphocytic colitis and 2(1.5%) had collagenous colitis. Patients with and without MC shared the same characteristics. Conclusion: A lower microscopic colitis frequency was found in the studied sample. Lymphocytic microscopic colitis is predominant than collagenous microscopic colitis.
目的评估巴基斯坦卡拉奇一家三甲医院慢性腹泻患者患显微镜下结肠炎的频率。研究设计:描述性横断面研究。研究地点巴基斯坦卡拉奇利亚卡特国立医院消化内科。时间:2022 年 1 月至 2022 年 6 月2022 年 1 月至 2022 年 6 月。材料与方法年龄大于 18 岁、腹泻病史大于 1 个月、甲状腺检查正常、乳糜泻血清学检查(抗 TTG IgA 和 IgG)阴性、结肠镜检查(包括回肠末端)结果正常的任何性别的门诊患者,在获得书面知情同意后纳入本研究。根据临床腹泻病史和结肠活检结果确定 MC 诊断。研究结果共分析了 130 名患者,中位年龄为 38 岁(IQR= 28-55 岁)。近一半为女性(67 人,51.5%)。所有患者的结肠镜检查结果均正常。在 130 例患者中,有 7 例(5.4%)患有显微结肠炎,其中 5 例(3.8%)患有淋巴细胞性结肠炎,2 例(1.5%)患有胶原性结肠炎。患有和未患有 MC 的患者具有相同的特征。结论在研究样本中发现,显微镜下结肠炎的发病率较低。淋巴细胞性镜下结肠炎比胶原性镜下结肠炎更常见。
{"title":"Frequency of microscopic colitis in patients presenting with chronic diarrhea.","authors":"Naik Muhammad, Mansoor-Ul-Haq, Adeel Rahat, Asad Abbas Jafri","doi":"10.29309/tpmj/2024.31.03.7757","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.03.7757","url":null,"abstract":"Objective: To evaluate frequency of microscopic colitis in patients presenting with chronic diarrhea at a tertiary care hospital in Karachi, Pakistan. Study Design: Descriptive Cross-sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan. Period: January, 2022 to June, 2022. Material & Methods: Patients presenting in out-patient department of age >18 years of any gender with history of diarrhea >1 month, normal thyroid tests, negative serology for Celiac disease (Anti TTG IgA and IgG), and normal colonoscopy findings including terminal ileum were enrolled in the study after written informed consent. MC diagnosis was established using clinical diarrhea history and colonic biopsy findings. Results: Total 130 patients were analyzed with median age of 38 (IQR= 28-55) years. Nearly half were females (n=67, 51.5%). All patients had normal colonoscopy findings. Out of 130 patients, microscopic colitis was seen among 7(5.4%) cases out of which 5(3.8%) had lymphocytic colitis and 2(1.5%) had collagenous colitis. Patients with and without MC shared the same characteristics. Conclusion: A lower microscopic colitis frequency was found in the studied sample. Lymphocytic microscopic colitis is predominant than collagenous microscopic colitis.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of morbidity of open cholecystectomy vs laparoscopic cholecystectomy in complicated gall stone disease. 复杂胆结石症中开腹胆囊切除术与腹腔镜胆囊切除术发病率的比较研究。
Pub Date : 2024-02-07 DOI: 10.29309/tpmj/2024.31.02.7885
Usama Shabbir, Jamal Anwar, Shahbaz Hussain, Mubashar Abrar, Ayesha Akram, Muhammad Ahsan, Ameer Afzal
Objective: To evaluate the resist of minimally invasive surgery i.e. laparoscopic cholecystectomy versus open cholecystectomy in cases with complex gallstone diseases. Study Design: Prospective study. Setting: North Surgical Ward, Mayo Hospital Lahore. Period: 11th July 2020 till 10th January 2021. Material & Methods: A total of 372 patient’s fulfilling the criterion was included for study in group-A Laparoscopic cholecystectomy was done. In group B open cholecystectomy was done which includes 86 patients. The entire patient received injection Ketorolac 30 mg i.e. 8 hourly and postoperative injection NeIbufin 6 mg i.v.12hourIy as standard in all patients and Post-operative pain was assessed Visual analogy scale after 24 hours. Results: The mean age of patients in open group was 41.28 ± 13.75 years and in Laparoscopic group was 43.46 ± 13.90 years. In Open group there were 80(43%) male and 106(57%) female cases while in Laparoscopic group there were 65(34.9%) male and 121(65.1%) female cases. The mean hospital stay was statistically shorter in Laparoscopic group (3.80 ± 1.37 days) as compared to Open group (5.12 ± 1.58 days), p-value <0.001. In open group 77(41.4%) cases had post-operative pain and in Laparoscopic group 27(14.5%) cases had post-operative pain. The post-operative pain was statistically higher in open groups, p-value < 0.001. Conclusion: Laparoscopic is an ideal treatment option in terms of less pain and shorter duration of hospital stay as compared to open cholecystectomy for patients with complicated gallstone disease.
目的评估微创手术(即腹腔镜胆囊切除术)与开腹胆囊切除术对复杂胆石症病例的耐受性。研究设计:前瞻性研究。研究地点拉合尔梅奥医院北外科病房。时间:2020 年 7 月 11 日至 10 日2020 年 7 月 11 日至 2021 年 1 月 10 日。材料与方法:A 组共纳入 372 名符合标准的患者进行研究,采用腹腔镜胆囊切除术。B 组包括 86 名患者,采用开腹胆囊切除术。所有患者均按标准每 8 小时注射开塞露 30 毫克,术后每 12 小时注射新布芬 6 毫克,24 小时后对术后疼痛进行视觉类比量表评估。结果:开腹组患者的平均年龄为(41.28 ± 13.75)岁,腹腔镜组患者的平均年龄为(43.46 ± 13.90)岁。开腹组中男性患者占 80 例(43%),女性患者占 106 例(57%);腹腔镜组中男性患者占 65 例(34.9%),女性患者占 121 例(65.1%)。据统计,腹腔镜组的平均住院时间(3.80 ± 1.37 天)比开腹组(5.12 ± 1.58 天)短,P 值小于 0.001。开腹组有 77 例(41.4%)术后疼痛,腹腔镜组有 27 例(14.5%)术后疼痛。据统计,开腹组的术后疼痛程度较高,P 值<0.001。结论与开腹胆囊切除术相比,腹腔镜是治疗复杂性胆石症患者的理想选择,疼痛更轻,住院时间更短。
{"title":"Comparative study of morbidity of open cholecystectomy vs laparoscopic cholecystectomy in complicated gall stone disease.","authors":"Usama Shabbir, Jamal Anwar, Shahbaz Hussain, Mubashar Abrar, Ayesha Akram, Muhammad Ahsan, Ameer Afzal","doi":"10.29309/tpmj/2024.31.02.7885","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.02.7885","url":null,"abstract":"Objective: To evaluate the resist of minimally invasive surgery i.e. laparoscopic cholecystectomy versus open cholecystectomy in cases with complex gallstone diseases. Study Design: Prospective study. Setting: North Surgical Ward, Mayo Hospital Lahore. Period: 11th July 2020 till 10th January 2021. Material & Methods: A total of 372 patient’s fulfilling the criterion was included for study in group-A Laparoscopic cholecystectomy was done. In group B open cholecystectomy was done which includes 86 patients. The entire patient received injection Ketorolac 30 mg i.e. 8 hourly and postoperative injection NeIbufin 6 mg i.v.12hourIy as standard in all patients and Post-operative pain was assessed Visual analogy scale after 24 hours. Results: The mean age of patients in open group was 41.28 ± 13.75 years and in Laparoscopic group was 43.46 ± 13.90 years. In Open group there were 80(43%) male and 106(57%) female cases while in Laparoscopic group there were 65(34.9%) male and 121(65.1%) female cases. The mean hospital stay was statistically shorter in Laparoscopic group (3.80 ± 1.37 days) as compared to Open group (5.12 ± 1.58 days), p-value <0.001. In open group 77(41.4%) cases had post-operative pain and in Laparoscopic group 27(14.5%) cases had post-operative pain. The post-operative pain was statistically higher in open groups, p-value < 0.001. Conclusion: Laparoscopic is an ideal treatment option in terms of less pain and shorter duration of hospital stay as compared to open cholecystectomy for patients with complicated gallstone disease.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"115 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139855537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency and distribution of co-morbidities in protein energy malnutrition children admitted in nutrition unit DHQ Hospital, District D.I. Khan, Pakistan. 巴基斯坦D.I. Khan区DHQ医院营养科收治的蛋白质能量营养不良儿童合并疾病的发病率和分布情况。
Pub Date : 2024-02-07 DOI: 10.29309/tpmj/2024.31.02.7787
Muhammad Ibrahim, Farid Ullah, Fawad Ahmed, Fazal ur Rehman, Sher Ullah, Muhammad Ilyas
Objective: To determine frequency and distribution of co-morbidities by type, age groups and gender in PEM children. Study Design: Cross-sectional study. Setting: Department of Pediatric (Nutrition Unit) and Community Medicine, GMC. Period: 15-8-2022, to 30-12-2022. Material & Methods: Data for diagnosed PEM cases was retrieved from Nutrition Unit DHQ Hospital DI Khan for which non-probability consecutive sampling technique was used. Research variable was type of comorbidities while demographics variables were age groups and gender. Association of gender and age groups with the presence or absence of co-morbidities in PEM children were found using Chi Square test. Results: Out of 400 participants, most frequent co-morbidity was gastroenteritis (GE) in 157(39.3%) patients in which females were 87(55.41%) and males 70(44.58%). 101(64.33%) were in 1–5-year age group and 56(35.66%) in under 1 year. Second to GE was pneumonia with 84(21%) patients in which females were 45(53.57%) and males 39(46.42%). Pneumonia in 1-5 year affected 61(72.61%) and 23(27.38%) patients were less than 1 year. Anemia affected 74(18.5%) patients in which females were 45(60.81%) and males 29(39.18%). 58(78.37%) patients were in 1-5 years and 16(21.62%) in less than 1 year. Other co-morbidities were seen in small number of patients. Difference in age groups were statistically significant at p-value of 0.005006 (<0.05) while there was no association of gender with comorbidities at p-value of 0.459344 (>0.05). Conclusion: Most common comorbidities were GE, pneumonia and anemia and their prevalence was higher in females and 1–5-year age group.
目的按类型、年龄组和性别确定 PEM 儿童并发症的频率和分布。研究设计:横断面研究。研究地点GMC 儿科(营养科)和社区医学系。期间:2022 年 8 月 15 日至 12 月 30 日2022 年 8 月 15 日至 2022 年 12 月 30 日。材料与方法:从 DI Khan DHQ 医院营养科获取已确诊的 PEM 病例数据,采用非概率连续抽样技术。研究变量为合并症类型,人口统计学变量为年龄组和性别。采用卡方检验(Chi Square test)发现性别和年龄组与 PEM 儿童是否存在并发症之间的关系。结果:在 400 名参与者中,157 名(39.3%)患者最常见的并发症是肠胃炎(GE),其中女性 87 名(55.41%),男性 70 名(44.58%)。101人(64.33%)的年龄在1-5岁之间,56人(35.66%)的年龄在1岁以下。其次是肺炎,有 84 名(21%)患者,其中女性 45 名(53.57%),男性 39 名(46.42%)。61(72.61%)名患者的肺炎病程为 1-5 年,23(27.38%)名患者的肺炎病程不足 1 年。74(18.5%)名患者贫血,其中女性 45(60.81%)名,男性 29(39.18%)名。58(78.37%)名患者的病程为 1-5 年,16(21.62%)名患者的病程不到 1 年。少数患者合并有其他疾病。各年龄组之间的差异具有统计学意义,P 值为 0.005006 (0.05)。结论最常见的并发症是 GE、肺炎和贫血,女性和 1-5 岁年龄组的发病率较高。
{"title":"Frequency and distribution of co-morbidities in protein energy malnutrition children admitted in nutrition unit DHQ Hospital, District D.I. Khan, Pakistan.","authors":"Muhammad Ibrahim, Farid Ullah, Fawad Ahmed, Fazal ur Rehman, Sher Ullah, Muhammad Ilyas","doi":"10.29309/tpmj/2024.31.02.7787","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.02.7787","url":null,"abstract":"Objective: To determine frequency and distribution of co-morbidities by type, age groups and gender in PEM children. Study Design: Cross-sectional study. Setting: Department of Pediatric (Nutrition Unit) and Community Medicine, GMC. Period: 15-8-2022, to 30-12-2022. Material & Methods: Data for diagnosed PEM cases was retrieved from Nutrition Unit DHQ Hospital DI Khan for which non-probability consecutive sampling technique was used. Research variable was type of comorbidities while demographics variables were age groups and gender. Association of gender and age groups with the presence or absence of co-morbidities in PEM children were found using Chi Square test. Results: Out of 400 participants, most frequent co-morbidity was gastroenteritis (GE) in 157(39.3%) patients in which females were 87(55.41%) and males 70(44.58%). 101(64.33%) were in 1–5-year age group and 56(35.66%) in under 1 year. Second to GE was pneumonia with 84(21%) patients in which females were 45(53.57%) and males 39(46.42%). Pneumonia in 1-5 year affected 61(72.61%) and 23(27.38%) patients were less than 1 year. Anemia affected 74(18.5%) patients in which females were 45(60.81%) and males 29(39.18%). 58(78.37%) patients were in 1-5 years and 16(21.62%) in less than 1 year. Other co-morbidities were seen in small number of patients. Difference in age groups were statistically significant at p-value of 0.005006 (<0.05) while there was no association of gender with comorbidities at p-value of 0.459344 (>0.05). Conclusion: Most common comorbidities were GE, pneumonia and anemia and their prevalence was higher in females and 1–5-year age group.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"97 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139794692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dyslipidemia: A risk factor for cataract. 血脂异常:白内障的危险因素
Pub Date : 2024-02-07 DOI: 10.29309/tpmj/2024.31.02.7902
Yasir Iqbal, Aqsa Malik, Masooma Talib, Iqra Anwar, Sohail Zia, Usman Arshad Qureshi
Objective: To determine lipid profile in patients of age-related cataract and compared them with age-matched controls. Study Design: Case Control study. Setting: Naseer Memorial Hospital, Dadyal. Period: January 2022 to December 2022. Material & Methods: A total of 300 patients were recruited using a consecutive non-probability sampling method and divided in two groups, one control and the other having cataract. The patients underwent a thorough ocular assessment and lipid profile evaluation. Inclusion criteria was age 40 years or older of any gender having senile cataracts of any morphological form. Exclusion criteria was history of ocular trauma, systemic disease, ocular surgery, oral steroids or cataract other than senile cause. The data was analyzed using SPSS version 23. The results showed that patients with senile cataracts had significantly higher levels of total cholesterol, triglycerides, and LDL cholesterol, and significantly lower levels of HDL cholesterol than the controls. The collected data was entered in the statistical package for social sciences (SPSS) version 21 for analysis. Independent t test was applied and p value ≤ 0.05 was considered as significant. Results: It was found that patients with senile cataracts had significantly higher levels of total cholesterol, triglycerides and LDL and significantly lower levels of HDL than the age-matched controls. Conclusion: The findings suggested that dyslipidemia is a modifiable risk factor for age-related cataract.
目的测定老年性白内障患者的血脂状况,并与年龄匹配的对照组进行比较。研究设计:病例对照研究。研究地点Dadyal 的纳赛尔纪念医院。时间:2022 年 1 月至 2022 年 12 月2022 年 1 月至 2022 年 12 月。材料与方法采用连续非概率抽样方法共招募了 300 名患者,并将其分为两组,一组为对照组,另一组为白内障组。患者接受了全面的眼部评估和血脂组合评估。纳入标准是年龄在 40 岁或以上,任何性别,患有任何形态的老年性白内障。排除标准是有过眼外伤、全身性疾病、眼部手术、口服类固醇或非老年性白内障病史。数据使用 SPSS 23 版进行分析。结果显示,老年性白内障患者的总胆固醇、甘油三酯和低密度脂蛋白胆固醇水平明显高于对照组,而高密度脂蛋白胆固醇水平明显低于对照组。收集的数据被输入社会科学统计软件包(SPSS)21 版进行分析。采用独立 t 检验,P 值小于 0.05 为差异显著。结果发现老年性白内障患者的总胆固醇、甘油三酯和低密度脂蛋白水平明显高于年龄匹配的对照组,而高密度脂蛋白水平明显低于对照组。结论研究结果表明,血脂异常是老年性白内障的一个可改变的风险因素。
{"title":"Dyslipidemia: A risk factor for cataract.","authors":"Yasir Iqbal, Aqsa Malik, Masooma Talib, Iqra Anwar, Sohail Zia, Usman Arshad Qureshi","doi":"10.29309/tpmj/2024.31.02.7902","DOIUrl":"https://doi.org/10.29309/tpmj/2024.31.02.7902","url":null,"abstract":"Objective: To determine lipid profile in patients of age-related cataract and compared them with age-matched controls. Study Design: Case Control study. Setting: Naseer Memorial Hospital, Dadyal. Period: January 2022 to December 2022. Material & Methods: A total of 300 patients were recruited using a consecutive non-probability sampling method and divided in two groups, one control and the other having cataract. The patients underwent a thorough ocular assessment and lipid profile evaluation. Inclusion criteria was age 40 years or older of any gender having senile cataracts of any morphological form. Exclusion criteria was history of ocular trauma, systemic disease, ocular surgery, oral steroids or cataract other than senile cause. The data was analyzed using SPSS version 23. The results showed that patients with senile cataracts had significantly higher levels of total cholesterol, triglycerides, and LDL cholesterol, and significantly lower levels of HDL cholesterol than the controls. The collected data was entered in the statistical package for social sciences (SPSS) version 21 for analysis. Independent t test was applied and p value ≤ 0.05 was considered as significant. Results: It was found that patients with senile cataracts had significantly higher levels of total cholesterol, triglycerides and LDL and significantly lower levels of HDL than the age-matched controls. Conclusion: The findings suggested that dyslipidemia is a modifiable risk factor for age-related cataract.","PeriodicalId":22991,"journal":{"name":"The professional medical journal","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139796322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The professional medical journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1