Topics in companion animal medicine最新文献_第4页

Surgical stabilization of a mandibular fracture in a pet African goose (Anser anser domesticus) with bilateral mandibular fractures 宠物非洲鹅（Anser Anser domesticus）双侧下颌骨骨折手术稳定。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-04-03 DOI: 10.1016/j.tcam.2025.100978

Seunga Min , Miranda J. Sadar , Taylr Wells , Amanda Day , Naomi Hoyer

A 7-month-old, 3.8 kg, female intact African goose (Anser anser domesticus), was presented on emergency after being struck by a metal chair during a strong gust of wind. Physical examination revealed ventral displacement of rostral portion of the mandible. A cone beam computed tomography (CBCT) scan confirmed complete, comminuted, bilateral fractures on the rostral portion of the mandibular body. Surgical intervention involved applying external fixation using self-threading Thread Mate System (TMS) pins, orthodontic chains, and dental acrylics to stabilize the right mandible. Indirect reduction and inherent stability were achieved on the left side. An esophagostomy tube was placed to prevent manipulation of the bill during feeding and medication administration in the post operative period. The goose prematurely removed the esophagostomy tube and dental acrylics 10 days after surgery. At the two week post-operative recheck, the bill was stable on palpation and the goose was using it for eating and drinking without complications. At follow-up examination one month after surgery, the goose continued to clinically do well, but all fixations had been self-removed. A repeat CBCT scan revealed bony callus formation of the left fracture site and fibrous callus with incomplete osseous bridging of the right fracture site consistent with delayed union. At 8 months post-operatively, the goose was clinically normal without functional impairment to the bill.

一只7个月大、3.8公斤重的完整非洲母鹅（Anser Anser domesticus）在强风中被金属椅击中后被紧急送往医院。体格检查显示下颌骨吻侧部腹侧移位。锥形束计算机断层扫描（CBCT）确认完整，粉碎性，双侧骨折在下颌体吻侧部分。手术干预包括使用自穿线螺纹配合系统（TMS）销钉、正畸链和牙科丙烯酸树脂进行外固定以稳定右下颌骨。在左侧实现了间接复位和固有稳定性。放置食管造口管以防止术后喂养和给药时操纵账单。手术后10天，这只鹅过早地取出了食管造口管和牙科丙烯酸树脂。术后两周复查，该喙触诊稳定，鹅用它进食和饮水，无并发症。术后1个月随访检查，鹅临床表现良好，但所有固定物均已自行取出。重复CBCT扫描显示左侧骨折部位骨痂形成，右侧骨折部位骨桥不完整，与延迟愈合一致。术后8个月，鹅临床正常，喙部无功能损伤。

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引用次数: 0

Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS) 评估副病毒感染犬全身炎症反应综合征（SIRS）的血液学指标。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-13 DOI: 10.1016/j.tcam.2025.100977

K. Sevim , E.Ç. Çolakoğlu , U. Kaya

Canine parvoviral enteritis (CPE) is a highly contagious, acute viral disease that mainly affects young dogs and can lead to systemic inflammatory response syndrome (SIRS), sepsis, endotoxemia and even death. The study aimed to evaluate the diagnostic and prognostic potential of hematological indices such as MLR, NLR, PLR, PNR and SII in CPV-infected dogs with SIRS at first admission. The retrospective study was performed on 51 CPV-infected and 20 healthy dogs. MLR, NLR, PLR, PNR, and SII indices were determined and compared between groups. A receiver operating characteristic (ROC) curve analysis was carried out to determine thresholds of sensitivity and specificity for hematologic indices.

NLR, PLR, and PNR were the best predictors for supporting a diagnosis of parvoviral enteritis, with AUC values of 0.685, 0.762, and 0.884, respectively. Moreover, PLR and PNR, with AUC values of 0.740 and 0.769, respectively, were the most suitable indices to determine the prognosis of dogs with parvoviral enteritis with SIRS. In conclusion, these indices can be used as potential indicators for predicting disease outcomes and supporting a diagnosis of CPV-infected dogs with SIRS at first admission.

犬细小病毒性肠炎（Canine parvoviral enteritis， CPE）是一种高度传染性的急性病毒性疾病，主要影响幼犬，可导致全身炎症反应综合征（systemic inflammatory response syndrome， SIRS）、败血症、内毒素血症甚至死亡。本研究旨在评价cpv感染的SIRS犬首次入院时MLR、NLR、PLR、PNR、SII等血液学指标对SIRS的诊断和预后价值。对51只cpv感染犬和20只健康犬进行回顾性研究。测定两组间MLR、NLR、PLR、PNR、SII指标并进行比较。进行受试者工作特征（ROC）曲线分析，确定血液学指标的敏感性和特异性阈值。NLR、PLR和PNR是支持细小病毒性肠炎诊断的最佳预测因子，AUC值分别为0.685、0.762和0.884。PLR和PNR的AUC值分别为0.740和0.769，是判断细小病毒性肠炎伴SIRS犬预后最合适的指标。综上所述，这些指标可作为预测疾病结局的潜在指标，支持cpv感染犬首次入院时SIRS的诊断。

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引用次数: 0

Dermal pathology in a Catahoula Leopard dog with Dermasparaxis Ehlers Danlos syndrome caused by a homozygous ADAMTS2 missense variant 由纯合子ADAMTS2错义变异引起的皮肤paraxis Ehlers Danlos综合征的Catahoula豹犬的皮肤病理。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-12 DOI: 10.1016/j.tcam.2025.100976

Jared A. Jaffey , Garrett Bullock , Martin L. Katz

Dermatosparaxis is a subtype of Ehlers-Danlos syndrome (dEDS) that typically results in euthanasia of dogs in the first several months of life because of complications mostly related to extreme skin fragility. The goal of this report was to describe ultrastructural features of collagen fibrils from a dog with a milder form of dEDS. A skin biopsy sample was procured from a nearly 10-year-old Catahoula Leopard dog with dEDS associated with a previously published homozygous missense variant in ADAMTS2. Light and electron microscopic examinations were performed. Light microscopic examination of the skin sample revealed a substantially reduced density of collagen fibers that were randomly oriented and appeared to have a decreased length. Electron microscopic examination revealed diameters of the fibrils were variable, and scattered fibrils had irregular cross-sectional profiles, but lacked the “hieroglyphic” appearance identified in dogs with the frameshift variant in ADAMTS2. Like other species with dEDS, dogs can have variable disease severities that includes dermal collagen abnormalities.

皮肤稀疏是埃勒-丹洛斯综合征（dEDS）的一种亚型，通常会在狗出生后的头几个月导致安乐死，因为并发症主要与皮肤极度脆弱有关。本报告的目的是描述胶原原纤维的超微结构特征，从狗与轻度形式的dEDS。从一只近10岁的Catahoula豹犬身上获得了皮肤活检样本，该犬患有与先前发表的ADAMTS2纯合错义变异相关的dEDS。进行了光镜和电镜检查。皮肤样本的光镜检查显示胶原纤维的密度大大降低，胶原纤维的随机取向和长度似乎减少了。电镜检查显示，原纤维的直径是可变的，分散的原纤维具有不规则的横截面，但缺乏ADAMTS2移码变异犬所特有的“象形”外观。与其他患有dEDS的物种一样，狗可能会有各种严重程度的疾病，包括真皮胶原蛋白异常。

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引用次数: 0

Case series of maggot debridement therapy demonstrates safety and efficacy for treating problematic wounds in cats and dogs in Mexico 在墨西哥，蛆虫清创疗法证明了治疗猫和狗的问题伤口的安全性和有效性。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-11 DOI: 10.1016/j.tcam.2025.100964

Alicia Fonseca-Muñoz , Aremí C. Lujano-Guzmán , Albert Nguyen , Ronald A. Sherman

Wound care is a common problem in small animals. Antimicrobial resistance, biofilm, time constraints, and the cost of surgery or specialized dressings hinder efforts to deliver prompt wound healing. Maggot therapy has been very effective in human and equine wound care, but very little research has evaluated its safety and efficacy in dogs and cats. This study was initiated to evaluate the utility, efficacy, and safety of maggot debridement therapy for wound care in a small animal veterinary practice in Mexico.

Six cats and four dogs were treated with maggot debridement therapy when their wounds failed to respond to conventional therapy. Treatment was administered by applying 8-10 larvae per cm² surface area directly on the wound bed and covering the wound with a sterile polyester mesh, sutured to the skin. These were left on the wound for cycles of approximately 48 h (24-72 h); the cycles were repeated if >20 % necrotic tissue remained after treatment.

Review of these cases revealed that 80 % of treated wounds achieved 100 % debridement within 48-96 h of treatment. An additional 10 % (one wound) achieved 80 % debridement within only 24 h of treatment. One animal failed to show improvement: a 3-year-old cat with an infected bite wound, which drained voluminously and drowned the maggots. This animal was deemed not to be an appropriate candidate for maggot debridement therapy, and treatment was terminated after just 12 h. Ultimately, this wound was debrided and closed surgically. No complications were encountered other than mild discomfort in one cat.

These results support claims that maggot debridement therapy is relatively safe and effective for treating problematic dog and cat wounds. Veterinarians should consider including maggot debridement among their treatment options for problematic wounds. Controlled clinical trials should be performed.

伤口护理是小动物的常见问题。抗菌素耐药性、生物膜、时间限制以及手术或专用敷料的费用阻碍了伤口迅速愈合的努力。蛆疗法对人类和马的伤口护理非常有效，但很少有研究评估其对狗和猫的安全性和有效性。本研究旨在评估墨西哥小动物兽医诊所伤口护理中蛆清创治疗的效用、有效性和安全性。当6只猫和4只狗的伤口对常规治疗无效时，他们接受了蛆虫清创治疗。治疗方法是将每平方厘米8-10只幼虫直接放在伤口床上，并用无菌聚酯网覆盖伤口，缝合到皮肤上。这些药物被放置在伤口上大约48小时（24-72小时）；如果治疗后仍有超过20%的坏死组织，则重复循环。对这些病例的回顾显示，80%的治疗伤口在48-96小时内实现了100%的清创。另外10%（一个伤口）在24小时内达到80%的清创。有一只动物没有表现出改善：一只3岁的猫，它的咬伤感染了，它大量排水，淹死了蛆虫。这只动物被认为不适合进行蛆虫清创治疗，治疗在12小时后就终止了。最终，该伤口被清理并手术闭合；没有其他动物需要手术干预。除一只猫出现轻微不适外，未出现并发症。这些结果支持了蛆清创疗法对于治疗有问题的狗和猫伤口是相对安全有效的说法。兽医应考虑将蛆虫清创纳入问题伤口的治疗方案。应进行对照临床试验。

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引用次数: 0

Characterization of Rhodococcus equi isolated from pyogranulomatous lesions in cats from Brazil 巴西猫脓肉芽肿性病变中分离的马红球菌的鉴定。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100962

Jamilly Rosa dos Santos , Renata Dalcol Mazaro , Alana Pivoto Herbichi , Rafael Almeida Fighera , Andrea Maria Lazzari , Sabrina dos Santos Costa Poggiani , Agueda Palmira Castagna de Vargas , Fernanda Silveira Flores Vogel , Juliana Felipetto Cargnelutti

This study aimed to describe and provide a laboratory characterization of three cases of Rhodococcus equi isolates from pyogranulomatous lesions in domestic cats in Brazil, collected between 2015 and 2021. Swabs and aspirates from nodular skin lesions located in the abdominal region (Case 1) and thoracic limbs (Cases 1–3) were subjected to microbiological culture, biochemical and molecular analyses, evaluation of biofilm formation capacity, and antimicrobial sensitivity testing. Cats 1 and 2 were positive for FeLV p27 antigen on SNAP testing. Cat 1 died at home from complications of Rhodococcus infection, and Cat 2 was euthanized following failure of medical and surgical treatment of infection. The cat in Case 3, which was FeLV-negative, received treatment with oral erythromycin and topical rifampicin for 30 days. However, due to failure of antimicrobial therapy to resolve the lesions, the cat underwent amputation of the affected right hindlimb. R. equi, positive for the plasmid-encoded virulence-associated protein A, was identified on the microbiological cultures and PCR from all cases. Biofilm formation analysis categorized all three isolates as weak biofilm formers. Additionally, antimicrobial susceptibility testing revealed that all isolates were sensitive to azithromycin, clarithromycin, erythromycin, imipenem, and rifampicin in vitro. These findings underscore the clinical, epidemiological, and laboratory characteristics of R. equi infection in Brazilian cats, indicating that these microorganisms are phenotypically and molecularly similar to those isolated from horses.

本研究旨在描述2015年至2021年间从巴西家猫脓肉芽肿性病变中分离的三例马红球菌，并提供实验室特征。对位于腹部（病例1）和胸肢（病例1-3）的结节性皮肤病变的拭子和抽吸液进行微生物培养、生化和分子分析、生物膜形成能力评估和抗菌药物敏感性测试。猫1和猫2在SNAP检测中FeLV p27抗原阳性。病例1因红球菌感染并发症在家中死亡，病例2因药物和手术治疗感染失败而被安乐死。病例3为felv阴性的猫，接受口服红霉素和局部利福平治疗30天。然而，由于抗菌治疗未能解决病变，猫接受了受影响的右后肢截肢。在所有病例的微生物培养中均鉴定出质粒编码毒力相关蛋白A阳性的马芮氏杆菌。生物膜形成分析将这三种分离物归类为弱生物膜形成物。体外对阿奇霉素、克拉霉素、红霉素、亚胺培南和利福平均敏感。这些发现强调了巴西猫中马雷氏菌感染的临床、流行病学和实验室特征，表明这些微生物在表型和分子上与从马中分离出来的微生物相似。

{"title":"Characterization of Rhodococcus equi isolated from pyogranulomatous lesions in cats from Brazil","authors":"Jamilly Rosa dos Santos , Renata Dalcol Mazaro , Alana Pivoto Herbichi , Rafael Almeida Fighera , Andrea Maria Lazzari , Sabrina dos Santos Costa Poggiani , Agueda Palmira Castagna de Vargas , Fernanda Silveira Flores Vogel , Juliana Felipetto Cargnelutti","doi":"10.1016/j.tcam.2025.100962","DOIUrl":"10.1016/j.tcam.2025.100962","url":null,"abstract":"<div><div>This study aimed to describe and provide a laboratory characterization of three cases of <em>Rhodococcus equi</em> isolates from pyogranulomatous lesions in domestic cats in Brazil, collected between 2015 and 2021. Swabs and aspirates from nodular skin lesions located in the abdominal region (Case 1) and thoracic limbs (Cases 1–3) were subjected to microbiological culture, biochemical and molecular analyses, evaluation of biofilm formation capacity, and antimicrobial sensitivity testing. Cats 1 and 2 were positive for FeLV p27 antigen on SNAP testing. Cat 1 died at home from complications of <em>Rhodococcus</em> infection, and Cat 2 was euthanized following failure of medical and surgical treatment of infection. The cat in Case 3, which was FeLV-negative, received treatment with oral erythromycin and topical rifampicin for 30 days. However, due to failure of antimicrobial therapy to resolve the lesions, the cat underwent amputation of the affected right hindlimb. <em>R. equi,</em> positive for the plasmid-encoded virulence-associated protein A, was identified on the microbiological cultures and PCR from all cases. Biofilm formation analysis categorized all three isolates as weak biofilm formers. Additionally, antimicrobial susceptibility testing revealed that all isolates were sensitive to azithromycin, clarithromycin, erythromycin, imipenem, and rifampicin in vitro. These findings underscore the clinical, epidemiological, and laboratory characteristics of <em>R. equi</em> infection in Brazilian cats, indicating that these microorganisms are phenotypically and molecularly similar to those isolated from horses.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100962"},"PeriodicalIF":1.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the effects of an opioid-free anesthetic protocol with two opioid-based protocols on the intraoperative cardiovascular response and postoperative pain in cats undergoing elective ovariohysterectomy: A prospective, randomized, blinded, clinical study 比较无阿片麻醉方案和两种阿片麻醉方案对接受择期卵巢切除术的猫术中心血管反应和术后疼痛的影响：一项前瞻性、随机、盲法临床研究。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100963

Bárbara Silva Correia, Eduardo Raposo Monteiro, João Victor Barbieri Ferronatto, Ivy Silva de La Rocque Pinho, Lívia Eichenberg Surita, Marcelo Meller Alievi

This study compared the cardiovascular response to surgery and postoperative pain between an opioid-free protocol and two opioid-based protocols in cats undergoing elective ovariohysterectomy. Cats were randomly allocated into three intramuscular premedication treatments: DEX (dexmedetomidine 7 µg/kg, n = 12), DEXMET (dexmedetomidine 7 µg/kg + methadone 0.3 mg/kg, n = 13) and DEXMOR (dexmedetomidine 7 µg/kg + morphine 0.3 mg/kg, n = 14). Preoperatively, all cats received meloxicam 0.1 mg/kg, subcutaneously. Anesthesia was induced with propofol and maintained with sevoflurane. Heart rate (HR) and systolic arterial pressure (SAP) were measured intraoperatively. Pain was assessed before premedication (Baseline) and postoperatively for 6 h using the Glasgow Composite Measure Pain Scale - Feline (CMPS-F) and Feline Grimace Scale (FGS). Rescue analgesia was given for CMPS-F scores ≥ 5.

In all groups, HR and SAP increased intraoperatively, but tachycardia (HR > 200 beats/min) or hypertension (SAP > 180 mmHg) did not occur. Postoperative CMPS-F scores were lower in DEXMET than in DEX; FGS scores in DEX and DEXMOR were higher than in DEXMET. Rescue analgesia was administered to 50 %, 23 % and 29 % cats in groups DEX, DEXMET and DEXMOR, respectively (p > 0.05). The odds ratio (95 % confidence interval) of receiving postoperative rescue analgesia within 6 h for opioid-free versus opioid-based techniques was 2.86 (0.76-11.43). All protocols allowed surgery to be performed without an exacerbated cardiovascular response. Incorporating methadone or morphine in the protocol decreased the odds of requiring postoperative rescue analgesia.

本研究比较了选择性卵巢子宫切除术的猫在无阿片类药物治疗方案和两种基于阿片类药物治疗方案之间对手术和术后疼痛的心血管反应。猫被随机分配到三个肌内术前用药法治疗:敏捷(dexmedetomidine 7µg / kg, n = 12),DEXMET (dexmedetomidine 7µg / kg + 美沙酮0.3毫克/公斤,n = 13)和DEXMOR (dexmedetomidine 7µg / kg + 吗啡0.3毫克/公斤,n = 14)。术前给予美洛昔康0.1 mg/kg皮下注射。麻醉由异丙酚诱导，七氟醚维持。术中测量心率（HR）和收缩压（SAP）。用药前（基线）和术后6小时使用格拉斯哥复合测量疼痛量表-猫（CMPS-F）和猫鬼脸量表（FGS）评估疼痛。CMPS-F评分≥5分给予抢救性镇痛。在所有组中，术中HR和SAP均升高，但未发生心动过速（HR > 200次/分）或高血压（SAP > 180 mmHg）。DEXMET组术后CMPS-F评分低于DEX组；DEX和DEXMOR组FGS评分高于DEXMET组。DEX组、DEXMET组和DEXMOR组分别对50%、23%和29%的猫进行抢救性镇痛（p < 0.05）。无阿片类药物与基于阿片类药物的技术在术后6小时内接受抢救性镇痛的优势比（95%置信区间）为2.86（0.76-11.43）。所有方案均允许在不加重心血管反应的情况下进行手术。在方案中加入美沙酮或吗啡降低了术后需要抢救性镇痛的几率。

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引用次数: 0

Cryptorchidism in dogs and cats presented for elective gonadectomy: A descriptive cohort study of 306 animals treated between 2018 and 2023 选择性性腺切除术中出现的狗和猫隐睾：一项描述性队列研究，对2018年至2023年间治疗的306只动物进行了研究。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100961

Seong Eun Cho , James M. Fudge , Suhee Kim , Bernie Page , DoHyeon Yu

The objective of this study was to describe the incidence, breed distribution, clinical findings (anatomic location, number of testicles affected, and side), and surgical management of cryptorchidism in dogs and cats presented for elective gonadectomy. Medical record abstracts from a non-profit, high-volume, high-quality, spay-neuter clinic from 2018 to 2023 were reviewed retrospectively for cases of elective surgical gonadectomy of cryptorchid dogs and cats. During the study period, 5,476 dogs and 11,559 cats were presented to the same facility for elective surgical castration, suggesting a cryptorchid incidence of 3.21 % for dogs and 1.12 % for cats. Cryptorchidism affects various breeds and body conformations. Cryptorchid testes were more commonly observed in the inguinal area than in the abdomen, and were more frequently located unilaterally on the right side in both dogs and cats. The mean number of overall incisions required for surgical management was higher for testes located in the abdomen than for those located in the inguinal region in both dogs and cats. Due to differences in anatomy, cryptorchid prevalence, and surgical techniques, cryptorchidism in dogs and cats should be evaluated separately. Careful, preemptive identification and localization of the retained testicle(s) can be beneficial for efficient excision of cryptorchid testes.

本研究的目的是描述选择性性腺切除术中犬和猫隐睾的发病率、品种分布、临床表现（解剖位置、受影响的睾丸数量和一侧）和手术处理。回顾性分析了2018-2023年一家非营利性、高容量、高质量的绝育诊所的病历摘要，其中包括隐睾犬和猫的选择性性腺切除术病例。在研究期间，5476只狗和11559只猫被送到同一机构进行选择性手术阉割，表明狗和猫的隐睾发生率分别为3.21%和1.12%。隐睾症影响各种品种和身体形态。隐睾在腹股沟区比腹部更常见，在狗和猫中更常位于单侧右侧。在狗和猫中，位于腹部的睾丸比位于腹股沟区域的睾丸需要手术治疗的平均总切口数量要高。由于解剖结构、隐睾患病率和手术技术的差异，狗和猫的隐睾应该分开评估。仔细地、预先地识别和定位保留的睾丸有助于有效地切除隐睾。

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引用次数: 0

All pet owners are not the same: End-of-Life caregiver expectations and profiles. 所有的宠物主人都不一样：临终关怀者的期望和简介。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-02-05 DOI: 10.1016/j.tcam.2025.100960

Sara Hoummady , Laureline Chaise , Marion Guillot , Nancy Rebout

The study aims to explore the specific needs of French pet owners who have experienced the loss of a pet, recognizing the limited focus on end-of-life and palliative care in veterinary practice. By characterizing owner profiles, the research seeks to enhance veterinary approaches and education to better address the unique challenges and emotional aspects associated with pet care and loss. An anonymous online survey was distributed to 302 French owners who already experienced the loss of an animal, including demographic information and feelings about their experience of a pet's end-of-life (EOL). Data were analysed using descriptive and qualitative analysis (including the use of AI chatbot ChatGPT). 56.6 % of participants reported a relatively smooth pet death, yet 67.0 % found the end-of-life period challenging. Three distinct owner groups emerged, each with varying needs. The first group expressed high guilt and a greater need for support, emphasizing the necessity for information and improved training. The second group, more informed and independent, benefits from veterinary support, while a leaflet suits them. The third group, competent in pain evaluation, requires less veterinary support. These differences highlight the importance of personalized owner support. The study proposes essential pillars for veterinarians and nurses' training, forming the EPITO system: Emotional support, Personalization, Information, Training, Tools, and Open discussion.

该研究旨在探索法国宠物主人的特殊需求，他们经历了宠物的损失，认识到兽医实践中对临终关怀和姑息治疗的关注有限。通过描述宠物主人的特征，该研究旨在加强兽医方法和教育，以更好地解决与宠物护理和失去相关的独特挑战和情感方面的问题。一项匿名在线调查向302名已经失去宠物的法国主人分发，包括人口统计信息和他们对宠物生命终结（EOL）经历的感受。数据分析使用描述性和定性分析（包括使用人工智能聊天机器人ChatGPT）。56.6%的参与者报告了相对平稳的宠物死亡，但67.0%的人认为生命的最后阶段具有挑战性。出现了三个不同的业主群体，每个群体都有不同的需求。第一组人表达了强烈的负罪感和对支持的更大需求，强调信息和改进培训的必要性。第二组人更了解情况，也更独立，他们受益于兽医的支持，而传单则适合他们。第三组，在疼痛评估能力，需要较少的兽医支持。这些差异突出了个性化所有者支持的重要性。该研究提出了兽医和护士培训的基本支柱，形成EPITO系统：情感支持、个性化、信息、培训、工具和公开讨论。

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引用次数: 0

Epidural administration of tramadol does not provide sufficient intraoperative analgesia for elective ovariohysterectomy in healthy cats 曲马多硬膜外给药不能为健康猫择期卵巢子宫切除术提供足够的术中镇痛。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-01-27 DOI: 10.1016/j.tcam.2025.100959

Franco IG , Souza AR , Costa IM , Julião GH , Oliveira BB , Nishimura HML , Abimussi CJX , Floriano BP

Few studies today address trans-operative analgesia provided by tramadol without local anesthetics for intra-abdominal procedures. The objective of this study was to assess the efficacy of trans-operative analgesia provided by epidurally administered tramadol in cats undergoing elective ovariohysterectomy. For this purpose, 16 healthy queens were randomly assigned to participate in one of two groups: GC, control group, 0.9% NaCl at 0.3 mL/kg; and GT, tramadol group, tramadol 1 mg/kg in saline to the same final volume. Subjects received premedication with ketamine, xylazine and morphine and were anesthetized and maintained with a propofol infusion at 0.4-0.8 mg/kg/min until the end of surgery. Variables heart rate (HR), respiratory rate (F_R) and systolic blood pressure (SAP) were recorded before epidural injection (TB), 5 minutes after epidural injection (TAE), at surgical incision of the skin (TSI), at clamping of the first ovarian pedicle (TP1), at clamping of the second pedicle (TP2), at clamping of the uterine stump (TU), at the beginning of abdominal cavity closure (TC) and at the final suture of the skin (TFS). A bolus of fentanyl 2 μg/kg was administered IV in case of a 20% increase of physiologic variables during these times. At the end of the study, data was analyzed using ANOVA for repeated measures followed by Tukey test. The number of fentanyl boluses was compared between groups using Kruskal-Wallis followed by Dunn test. All analyses were performed under 5% significance. There were no significant differences in HR, F_R and SAP between groups. Only a mild difference was seen in HR in GT at times MP1, MP2, MU and MC compared to baseline (before epidural injections). There were no differences in number of fentanyl boluses between groups, with median (range) of 3 (1–5) in GC and 3 (1–4) in GT. In conclusion, tramadol given epidurally to cats undergoing elective ovariohysterectomy does not provide reliable intraoperative analgesia, and therefore other strategies are necessary to ensure intraoperative analgesia of healthy cats during elective ovariohysterectomy.

目前很少有研究涉及曲马多在腹内手术中不使用局麻药的术中镇痛。本研究的目的是评估硬膜外给药曲马多对择期卵巢子宫切除术猫的术中镇痛效果。为此，将16只健康的蜂王随机分为两组：GC组，对照组，0.9% NaCl, 0.3 mL/kg；GT组曲马多1 mg/kg生理盐水至等量。用药前给予氯胺酮、噻嗪和吗啡，麻醉后以0.4 ~ 0.8 mg/kg/min异丙酚输注维持至手术结束。记录硬膜外注射前（TB）、硬膜外注射后5分钟（TAE）、皮肤手术切口（TSI）、卵巢第一个蒂夹紧（TP1）、第二个蒂夹紧（TP2）、子宫残端夹紧（TU）、腹腔闭合开始（TC）和皮肤最后缝合（TFS）时的可变心率（HR）、呼吸频率（FR）和收缩压（SAP）。在此期间，如果生理指标增加20%，则静脉注射芬太尼2 μg/kg。研究结束时，采用方差分析对重复测量数据进行分析，并进行Tukey检验。采用Kruskal-Wallis和Dunn试验比较各组芬太尼剂量。所有分析均在5%显著性下进行。两组间HR、FR、SAP均无显著差异。与基线（硬膜外注射前）相比，GT患者MP1、MP2、MU和MC时的HR仅有轻微差异。各组之间芬太尼丸的数量没有差异，GC组中位（范围）为3 (1-5)，GT组中位（范围）为3（1-4）。综上所示，选择性卵巢子宫切除术猫硬膜外给曲马多不能提供可靠的术中镇痛，因此需要其他策略来确保健康猫在选择性卵巢子宫切除术期间的术中镇痛。

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引用次数: 0

Analysis of selected nutrients and contaminants in fish oil supplements for dogs* 犬用鱼油补充剂中选定营养素和污染物的分析。

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Topics in companion animal medicine

Pub Date : 2025-01-06 DOI: 10.1016/j.tcam.2025.100949

Lauren R. Ober , Jennifer A. Larsen , Lauren E. Hoffman , Birgit Puschner , Andrea J. Fascetti

Fish oil supplements for dogs are used therapeutically for various clinical conditions. However, products may be variable in quality, potency, and stability. The objective of this study was to analyze eleven canine fish oil supplements from two time points (2010 and 2021) for the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), polychlorinated biphenyl (PCB) arochlors, minerals, and vitamins A and D, and to compare their compositions to label claims. Molybdenum, cadmium, mercury, lead, and PCBs were not detected in any samples. Other minerals were detected in some products, and concentrations were well below general maximum tolerable levels or applicable regulatory maximums for dog foods. EPA and DHA concentrations varied widely among products and between timepoints. Overall, there were six instances of products not meeting label claims within 5 % for EPA, DHA, or both. Across both timepoints, five minimum content claims were made for vitamin A, and three for vitamin D. In 2010, the analyzed concentrations were below the claims for one product each for vitamins A and D, while for 2021 all products met their respective claims. Overall, products were assessed to have low risk for vitamins A and D or mineral toxicoses when used as recommended. At higher (therapeutic) doses, contributions to the overall intake for nutrients of concern should be considered, including selenium and fat soluble vitamins. In addition, there is room for improvement for manufacturers to ensure accurate label guarantees.

狗的鱼油补充剂用于治疗各种临床条件。然而，产品在质量、效力和稳定性方面可能是可变的。本研究的目的是分析2010年和2021年两个时间点的11种犬鱼油补充剂中omega-3脂肪酸二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）、多氯联苯（PCB）芳烃、矿物质和维生素A和D的含量，并将其成分与标签上的声明进行比较。钼、镉、汞、铅和多氯联苯均未在任何样品中检测到。在一些产品中检测到其他矿物质，其浓度远低于一般最高可耐受水平或适用的狗粮最高监管标准。EPA和DHA的浓度在不同的产品和不同的时间点之间差异很大。总的来说，有六种产品的EPA、DHA含量在5%以内，或两者都不符合标签上的要求。在这两个时间点上，维生素A有5个最低含量声明，维生素D有3个最低含量声明。2010年，所分析的维生素A和维生素D的浓度分别低于一种产品的最低含量声明，而2021年，所有产品都达到了各自的要求。总体而言，经评估，这些产品在按建议使用时，维生素A和D或矿物质中毒的风险较低。在较高的（治疗）剂量下，应考虑对所关注的营养素的总摄入量的贡献，包括硒和脂溶性维生素。此外，在标签保证方面，制造商在确保准确标签方面还有改进的余地。

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引用次数: 0