Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609922
Aniwat Juhong, W. Piyawattanametha
We have developed a fluorescence based detection for rapid E. coli which is an indicator for fecal contamination for water quality. This technology has cut down the time taken to detect E. coli from a few days to just a couple of hours. The system relies on the enzyme β-D glucuronidase (GUD) reacts with 4-methylumblliferyl-β-D glucuronide (MUG) resulting in a byproduct named 4-methylumbellliferone (4MU). Our system can detect this byproduct in the concentration range from 0.01 to 80 μM which can then be enumerated to be the number of E. coli.
{"title":"An E. coli screening machine in water via fluorescence detection","authors":"Aniwat Juhong, W. Piyawattanametha","doi":"10.1109/BMEICON.2018.8609922","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609922","url":null,"abstract":"We have developed a fluorescence based detection for rapid E. coli which is an indicator for fecal contamination for water quality. This technology has cut down the time taken to detect E. coli from a few days to just a couple of hours. The system relies on the enzyme β-D glucuronidase (GUD) reacts with 4-methylumblliferyl-β-D glucuronide (MUG) resulting in a byproduct named 4-methylumbellliferone (4MU). Our system can detect this byproduct in the concentration range from 0.01 to 80 μM which can then be enumerated to be the number of E. coli.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122550193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609988
Chen-Hsun Weng, Hsin-Yi Chou, Ming-Huang Chen, Yu-Sheng Lin
Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.
{"title":"A portable platform for the quantification of vitamin D levels by using paper-based microfluidic","authors":"Chen-Hsun Weng, Hsin-Yi Chou, Ming-Huang Chen, Yu-Sheng Lin","doi":"10.1109/BMEICON.2018.8609988","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609988","url":null,"abstract":"Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123003055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609919
T. Igasaki, Kent Yamashita, Takeshi Ushijima
The coherence between electroencephalogram (EEG) and electromyogram (EMG) of the tibialis anterior (TA) muscle during isometric contraction is observed in the beta band (15 to 35 Hz). When the contraction force becomes stronger, the peak coherence frequency shifts to the gamma band (35 to 60 Hz). In contrast, based on the maintenance of contraction with the weak force, the peak coherence value increases. However, the manner in which coherence changes according to the maintenance of contraction with strong force remains unknown. In this study, five healthy male university students were directed to execute isometric contraction by dorsiflexion of their right ankle joint for 1 min with forces of 10 to 60% of the maximum voluntary contraction. During dorsiflexion, EEG and EMG of the TA muscle were performed. Then, the changes in coherence between EEG and EMG were examined, corresponding to the changes in contraction force and time course. In the majority of subjects, the peak coherence during the weak contraction force was observed in the beta band and lasted for 12 to 60 s. However, the peak coherence during the strong contraction force was observed in the gamma band only for the first 12 s. Subsequently, no significant coherence was observed. Therefore, muscle fatigue due to strong contraction forces and/or maintenance of the weak contraction force may have been observed as a different property of the peak coherence.
{"title":"Force-Temporal Characteristics of EEG-EMG Coherence During Isometric Contraction of the Tibialis Anterior Muscle","authors":"T. Igasaki, Kent Yamashita, Takeshi Ushijima","doi":"10.1109/BMEICON.2018.8609919","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609919","url":null,"abstract":"The coherence between electroencephalogram (EEG) and electromyogram (EMG) of the tibialis anterior (TA) muscle during isometric contraction is observed in the beta band (15 to 35 Hz). When the contraction force becomes stronger, the peak coherence frequency shifts to the gamma band (35 to 60 Hz). In contrast, based on the maintenance of contraction with the weak force, the peak coherence value increases. However, the manner in which coherence changes according to the maintenance of contraction with strong force remains unknown. In this study, five healthy male university students were directed to execute isometric contraction by dorsiflexion of their right ankle joint for 1 min with forces of 10 to 60% of the maximum voluntary contraction. During dorsiflexion, EEG and EMG of the TA muscle were performed. Then, the changes in coherence between EEG and EMG were examined, corresponding to the changes in contraction force and time course. In the majority of subjects, the peak coherence during the weak contraction force was observed in the beta band and lasted for 12 to 60 s. However, the peak coherence during the strong contraction force was observed in the gamma band only for the first 12 s. Subsequently, no significant coherence was observed. Therefore, muscle fatigue due to strong contraction forces and/or maintenance of the weak contraction force may have been observed as a different property of the peak coherence.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127283991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609925
N. Torsutkanok, N. Thongpance, A. Wongkamhamg
This development of smart dental unit is the collaboration between College of Biomedical Engineering, Rangsit University and C.C. AUTOPART Co., Ltd. The purpose of this project is to develop the smart dental unit system to obtain product certification for Thai Industrial Standard and reduce the import of medical instruments from foreign country. The development process started from review, the research prototype development and efficiency improvement that comply with the Thai Industrial Standard. In this study, the research team focused on the technical development process and the functional corrections of the dental unit system in order to obtain the test results conform with laboratory standards, which consists of two main components as follows: (1) Structure of dental chair have made from cast iron that can be operated by using PIC18F26K22 microcontroller and (2) Online monitoring and notification system which are; Water Pressure System in the range of 2–8 Bar, Main Air Pressure in the range of 4–12 Bar, Air Pressure of Dental Bur in the range of 2–6 Bar, Core Voltage in the range of 184–240 VAC., Hydraulic system which has 100–300 mA., Solenoid Valve which active in the range of 100–300 mA., Electric Current of Dental Lamp which has range between 100–300 mA, Oil level (HL) and Safety Switch can save the data to the server at a prescribed period of time from 1 to 30 minutes. The preliminary test results of both parts were established from the NECTEC and PTEC labs, respectively. The results show that they are in accordance with TIS 2610-2556 and the prototype has the potential to a commercial product in near future.
{"title":"The Development of Smart Dental Unit","authors":"N. Torsutkanok, N. Thongpance, A. Wongkamhamg","doi":"10.1109/BMEICON.2018.8609925","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609925","url":null,"abstract":"This development of smart dental unit is the collaboration between College of Biomedical Engineering, Rangsit University and C.C. AUTOPART Co., Ltd. The purpose of this project is to develop the smart dental unit system to obtain product certification for Thai Industrial Standard and reduce the import of medical instruments from foreign country. The development process started from review, the research prototype development and efficiency improvement that comply with the Thai Industrial Standard. In this study, the research team focused on the technical development process and the functional corrections of the dental unit system in order to obtain the test results conform with laboratory standards, which consists of two main components as follows: (1) Structure of dental chair have made from cast iron that can be operated by using PIC18F26K22 microcontroller and (2) Online monitoring and notification system which are; Water Pressure System in the range of 2–8 Bar, Main Air Pressure in the range of 4–12 Bar, Air Pressure of Dental Bur in the range of 2–6 Bar, Core Voltage in the range of 184–240 VAC., Hydraulic system which has 100–300 mA., Solenoid Valve which active in the range of 100–300 mA., Electric Current of Dental Lamp which has range between 100–300 mA, Oil level (HL) and Safety Switch can save the data to the server at a prescribed period of time from 1 to 30 minutes. The preliminary test results of both parts were established from the NECTEC and PTEC labs, respectively. The results show that they are in accordance with TIS 2610-2556 and the prototype has the potential to a commercial product in near future.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127800319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609987
Joompon Bamrungwong, P. Woraratsoontorn
Human femur broken is one of the most frequent type of bone fractures. Basically, the widely used techniques in an internal repair is using the Dynamic Compression Plate (DCP). In addition to the configuration of the screw position plays a major role of the DCP stress, the varus and valgus knee is a factor as well. This research is proposed to investigate the stress distribution go around on the DCP by vary angle of a femur represent to valgus knee using Finite Element Analysis (FEA). To find out the stress, the body weight assumed to be constant at 70 kg. The DCP with the screws were fixed on femur for 12 units. The results from finite element analysis were compared with other authors for the normal conditions, the results moved on the same way. The results were found that the maximum Von Mises stress on the DCP was occurred on the unused hole. Both valgus and varus knee the maximum reaction forces is at lateral condyle than medial condyle and the delta of reaction forces go around 310 N plus. Both valgus and varus knee can be fixed by using DCP if the femur take angle with vertical line not reach 20 degrees. From the results also reveals that osteoarthritis from valgus knee more severe than varus knee, female have a chance to face osteoarthritis more than male due to femur angle of female larger than male.
人类股骨骨折是最常见的骨折类型之一。基本上，在内部修复中广泛使用的技术是使用动态加压钢板(DCP)。除了螺钉位置的配置对DCP应力起主要作用外，膝关节内翻和外翻也是一个因素。本研究采用有限元分析方法研究股骨与外翻膝关节在不同角度下的应力分布。为了找出压力，假设体重恒定在70公斤。将DCP与螺钉固定在股骨上12个单位。在正常情况下，将有限元分析结果与其他作者的结果进行了比较，结果一致。结果发现，未使用孔对DCP产生最大的Von Mises应力。无论是外翻还是膝内翻，最大的反作用力都在外侧髁处，而不是内侧髁处，反作用力的δ约为310 N +。当股骨与垂直线夹角不超过20度时，均可采用DCP固定外翻和膝内翻。结果还表明，外翻性膝关节炎比膝内翻性膝关节炎严重，女性股骨角度大于男性，女性患骨关节炎的几率大于男性。
{"title":"The Modeling Study of Stress on Femur and DCP with Valgus and Varus Knee","authors":"Joompon Bamrungwong, P. Woraratsoontorn","doi":"10.1109/BMEICON.2018.8609987","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609987","url":null,"abstract":"Human femur broken is one of the most frequent type of bone fractures. Basically, the widely used techniques in an internal repair is using the Dynamic Compression Plate (DCP). In addition to the configuration of the screw position plays a major role of the DCP stress, the varus and valgus knee is a factor as well. This research is proposed to investigate the stress distribution go around on the DCP by vary angle of a femur represent to valgus knee using Finite Element Analysis (FEA). To find out the stress, the body weight assumed to be constant at 70 kg. The DCP with the screws were fixed on femur for 12 units. The results from finite element analysis were compared with other authors for the normal conditions, the results moved on the same way. The results were found that the maximum Von Mises stress on the DCP was occurred on the unused hole. Both valgus and varus knee the maximum reaction forces is at lateral condyle than medial condyle and the delta of reaction forces go around 310 N plus. Both valgus and varus knee can be fixed by using DCP if the femur take angle with vertical line not reach 20 degrees. From the results also reveals that osteoarthritis from valgus knee more severe than varus knee, female have a chance to face osteoarthritis more than male due to femur angle of female larger than male.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129310420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609971
Kazuki Hiramoto, K. Hamamoto
The purposes of this research are to investigate the information necessary for cognition of the VR environment using “Reaching” and to examine how to compensate the difference of cognition between the real and the VR environment. Therefore, this research conducts a task in VR to acquire cognition with the VR environment (Cognitive acquisition task) first. This task is one for a subject to be acclimated to VR environment. The important thing is that the subject’s arms and hands and their actions are shown in VR environment using CG. Second, comparative experiment using Reaching is conducted. Cognitive acquisition task is conducted using simple action task related to reaching, such as stacking blocks and rolling spheres. In Reaching experiment, first, a subject estimate whether the subject can grasp a cylinder placed in front of the subject by just stretching arms in thought. After that, the subject grabs the cylinder and places it as far as possible. The results are investigated in the real and the virtual environment. In the real, it has been found that the longest distance to an object for a person to decide to be able to reach for and grab the object (CDDG) is about 1.1 times as long as the longest distance where a person actually can reach for grabbing the object (CRDG). The previous studies have shown that the ratio of CDDG and CRDG in VR is not 1.1 and its compensation is difficult. However, as a result of this research experiment, CDDGs in this research were the same value in the real and the VR environment. And in the case of VR with reduced environmental information, CDDG in VR was different from one in real. As the result, it was suggested that the difference in cognition could be compensated by including the necessary and sufficient environmental and user’s information (CG model of user’s body and user’s movement) and an appropriate cognition could be realized even in the current VR environment.
{"title":"Study on the Difference of Reaching Cognition Between the Real and the Virtual Environment Using HMD and its Compensation","authors":"Kazuki Hiramoto, K. Hamamoto","doi":"10.1109/BMEICON.2018.8609971","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609971","url":null,"abstract":"The purposes of this research are to investigate the information necessary for cognition of the VR environment using “Reaching” and to examine how to compensate the difference of cognition between the real and the VR environment. Therefore, this research conducts a task in VR to acquire cognition with the VR environment (Cognitive acquisition task) first. This task is one for a subject to be acclimated to VR environment. The important thing is that the subject’s arms and hands and their actions are shown in VR environment using CG. Second, comparative experiment using Reaching is conducted. Cognitive acquisition task is conducted using simple action task related to reaching, such as stacking blocks and rolling spheres. In Reaching experiment, first, a subject estimate whether the subject can grasp a cylinder placed in front of the subject by just stretching arms in thought. After that, the subject grabs the cylinder and places it as far as possible. The results are investigated in the real and the virtual environment. In the real, it has been found that the longest distance to an object for a person to decide to be able to reach for and grab the object (CDDG) is about 1.1 times as long as the longest distance where a person actually can reach for grabbing the object (CRDG). The previous studies have shown that the ratio of CDDG and CRDG in VR is not 1.1 and its compensation is difficult. However, as a result of this research experiment, CDDGs in this research were the same value in the real and the VR environment. And in the case of VR with reduced environmental information, CDDG in VR was different from one in real. As the result, it was suggested that the difference in cognition could be compensated by including the necessary and sufficient environmental and user’s information (CG model of user’s body and user’s movement) and an appropriate cognition could be realized even in the current VR environment.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115654865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609972
Enid W Y Kwong, G. Pang
This paper presents an intelligent seat that can monitor the seat pressure with an aim of relieving the seat pressure for the prevention of pressure ulcers. Advanced thin-sheet force sensors are used to measure the seat pressure in real-time. Different sitting surfaces have been used to evaluate the developed pressure sensing mat. Robotic extension/retraction mechanisms are used from the base of the seat with an aim to redistribute the seat pressure on the top. The developed biomechanics has the potential to treat early stage pressure ulcers in elders. The developed seat can alleviate the problem of pressure ulcers that occur commonly in many seniors and elders especially in nursing homes.
{"title":"Development of an Intelligent Seat for the Alleviation of Pressure Ulcers","authors":"Enid W Y Kwong, G. Pang","doi":"10.1109/BMEICON.2018.8609972","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609972","url":null,"abstract":"This paper presents an intelligent seat that can monitor the seat pressure with an aim of relieving the seat pressure for the prevention of pressure ulcers. Advanced thin-sheet force sensors are used to measure the seat pressure in real-time. Different sitting surfaces have been used to evaluate the developed pressure sensing mat. Robotic extension/retraction mechanisms are used from the base of the seat with an aim to redistribute the seat pressure on the top. The developed biomechanics has the potential to treat early stage pressure ulcers in elders. The developed seat can alleviate the problem of pressure ulcers that occur commonly in many seniors and elders especially in nursing homes.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115896603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609978
Benjamas Ponboonjaroenchai, Malee Sutthiopad, J. Kanchanawarin, C. Luengviriya, J. Luengviriya, S. Müller
Propagating excitations in forms of spiral waves occur in various excitable media governed by reaction-diffusion mechanisms. They have an important impact on human health since they correspond to cardiac arrhythmia and potentially cause life-threatening fibrillation. The spiral waves and the corresponding pathological conditions stay longer when the spiral waves are pinned to unexcitable obstacles, e.g., blood vessels or scars in the heart. We present a method to initiate two-armed spiral waves pinned to a circular obstacle. The initiation is successful when the obstacle diameter is larger than a critical value that increases with the system excitability. This due to the fact the areas close to the partitions sufficiently recover for the next excitation. For obstacles smaller than the critical diameter, the spiral waves fail to be pinned and subsequently two separate free spiral waves occupy the system. While the free spiral waves depend solely on the excitability, the two-armed pinned spiral waves are influenced by both the obstacle size and the excitability.
{"title":"Initiation of two-armed spiral waves pinned to obstacles in simulated excitable media","authors":"Benjamas Ponboonjaroenchai, Malee Sutthiopad, J. Kanchanawarin, C. Luengviriya, J. Luengviriya, S. Müller","doi":"10.1109/BMEICON.2018.8609978","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609978","url":null,"abstract":"Propagating excitations in forms of spiral waves occur in various excitable media governed by reaction-diffusion mechanisms. They have an important impact on human health since they correspond to cardiac arrhythmia and potentially cause life-threatening fibrillation. The spiral waves and the corresponding pathological conditions stay longer when the spiral waves are pinned to unexcitable obstacles, e.g., blood vessels or scars in the heart. We present a method to initiate two-armed spiral waves pinned to a circular obstacle. The initiation is successful when the obstacle diameter is larger than a critical value that increases with the system excitability. This due to the fact the areas close to the partitions sufficiently recover for the next excitation. For obstacles smaller than the critical diameter, the spiral waves fail to be pinned and subsequently two separate free spiral waves occupy the system. While the free spiral waves depend solely on the excitability, the two-armed pinned spiral waves are influenced by both the obstacle size and the excitability.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125167312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609952
Airi Asano, M. Shiibashi, H. Kudo
A miniaturized electrochemical-oxytocin (OXT) sensor using competitive ELISA was constructed and tested. The OXT sensor measures OXT as reduction of glucose oxidase-labeled oxytocin, which competitively captured by anti-OXT antibodies. We employed a nitrocellulose membrane as a support for antibody because the nitrocellulose membrane improved the output signal by two folds comparing with using a microtiter plate as a support. In the experiment, competitive immunoreaction was first optically measured using conventional biotinylated capture antibody and avidin-GOD. As a result, it was confirmed that oxytocin measurement was possible by the constructed immune system. After that, oxytocin was electrochemically measured on the electrode using a carbon graphite electrode. Redox currents showed a relationship with oxytocin concentration and the calibration range involved 15pg/mL, which has been reported as salivary oxytocin.
{"title":"Development of an Electrochemical Immunosensor for Salivary Oxytocin Determination","authors":"Airi Asano, M. Shiibashi, H. Kudo","doi":"10.1109/BMEICON.2018.8609952","DOIUrl":"https://doi.org/10.1109/BMEICON.2018.8609952","url":null,"abstract":"A miniaturized electrochemical-oxytocin (OXT) sensor using competitive ELISA was constructed and tested. The OXT sensor measures OXT as reduction of glucose oxidase-labeled oxytocin, which competitively captured by anti-OXT antibodies. We employed a nitrocellulose membrane as a support for antibody because the nitrocellulose membrane improved the output signal by two folds comparing with using a microtiter plate as a support. In the experiment, competitive immunoreaction was first optically measured using conventional biotinylated capture antibody and avidin-GOD. As a result, it was confirmed that oxytocin measurement was possible by the constructed immune system. After that, oxytocin was electrochemically measured on the electrode using a carbon graphite electrode. Redox currents showed a relationship with oxytocin concentration and the calibration range involved 15pg/mL, which has been reported as salivary oxytocin.","PeriodicalId":232271,"journal":{"name":"2018 11th Biomedical Engineering International Conference (BMEiCON)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123558558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-01DOI: 10.1109/BMEICON.2018.8609998
Chawakorn Sri-ngernyuang, P. Youngkong, D. Lasuka, K. Thamrongaphichartkul, Watcharapong Pingmuang
One of the critical issues in hospitals is the injury from falling out of patient bed. Some of these cases lead to death. Considering this type of incident, a monitoring and alarming system called NEFs (Never Ever Falls) is introduced to prevent patients from falling out of the bed. In this paper, on-bed pattern recognition is developed by applying Neural Network Pattern Recognition from MATLAB. In the experiment, data from 6 persons in 5 different on-bed patterns (Sitting inside the bed, Supine, Lateral on the left, Lateral on the right and sitting at bedsides and corners) is recorded. According to the confusion matrix, training and validation confusion tables show 99.5% and 89.1% accuracy, respectively.
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