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2018 11th Biomedical Engineering International Conference (BMEiCON)最新文献

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Footprint Identification using Deep Learning 使用深度学习的足迹识别
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609926
Tanapon Keatsamarn, C. Pintavirooj
Human footprint is the biometric system of the individual person. Everyone has specific footprints. It can be used instead of password-based authentication in the security system such as a user authentication for the financial transaction. The password-based system cannot verify that the person who entered the password is valid or not. Therefore the biometric system is more secure than the password-based system. For that reason, it’s interesting to use footprint image in the creating of the footprint-based identification system. In this paper, the convolutional neural network training is used for deep learning classification. Convolutional neural networks are essential for deep learning and suited for image recognition.
人类足迹是个体的生物识别系统。每个人都有特定的足迹。它可以在安全系统中代替基于密码的身份验证,例如用于金融事务的用户身份验证。基于密码的系统无法验证输入密码的人是否有效。因此,生物识别系统比基于密码的系统更安全。因此,在创建基于足迹的识别系统时使用足迹图像是很有趣的。本文将卷积神经网络训练用于深度学习分类。卷积神经网络对于深度学习和图像识别至关重要。
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引用次数: 7
Investigation of Leukocyte Viability in A Setup of Spiral Microchannel for Cell Sorting Application 细胞分选用螺旋微通道装置中白细胞活力的研究
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609967
Thammawit Suwannaphan, A. Pimpin, W. Srituravanich, A. Sailasuta, Theerayuth Kaewamatawomg, W. Jeamsaksiri, W. Sripumkhai, P. Piyaviriyakul, S. Bhanpattanakul
Recently, a spiral microchannel has been receiving remarkable attentions in a field of biology for cell separation. Because it could separate different sizes of cells and has potential to integrate together with other components for a biological study of a single cell. However, hydrodynamic forces in spiral section and other components could potentially cause cell to death and change in cell physical and biological properties, but there was rarely such study so far. Therefore, the investigation of cell viability in a setup of spiral microchannel including feeding system and spiral microchannel was performed in this work. Beside the cell viability investigation, the change in cell morphology and intracellular structures were also investigated. The results indicated that stresses—extensional and shear stresses might be the important factors affecting cell death. The significant loss of cell viability was not found in feeding system but 15–18% of cell loss occurred in a spiral microchannel instead.
近年来,螺旋微通道在细胞分离生物学领域受到了广泛的关注。因为它可以分离不同大小的细胞,并有可能与其他成分整合在一起,以进行单细胞的生物学研究。然而,螺旋截面和其他部件的水动力作用可能导致细胞死亡,改变细胞的物理和生物特性,但目前很少有这方面的研究。因此,本研究在螺旋微通道的设置下进行了细胞活力的研究,包括进料系统和螺旋微通道。除了细胞活力的研究外,还研究了细胞形态和细胞内结构的变化。结果表明,应力-拉伸和剪切应力可能是影响细胞死亡的重要因素。在饲喂系统中没有发现明显的细胞活力损失,但15-18%的细胞损失发生在螺旋微通道中。
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引用次数: 2
Model Analysis of Artificial Knee Joint : Comparison of Cruciate Retaining Type and Posterior Stabilized Type 人工膝关节模型分析:十字保留型与后路稳定型的比较
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609923
Y. Kawagoe, Tomoko Kajiwara, Michihiko Fukunaga
The objective of this study is to analyze statics and kinematics of artificial knee joint at deep flexion to compared the difference between cruciate retaining (CR) type and posterior stabilized (PS) type. We performed a 3D model analysis with conditions of point contact and force/moment equilibrium. The motion to be subjected was passive knee flexion at the flexion angle from 30° to 150°. As a result, patellofemoral and tibiofemoral forces of PS type were smaller than CR type. Besides, with CR type, femoral rollback and tibial internal rotation were observed when the posterior cruciate ligament (PCL) stiffness was large, which are usually observed the physiological knee kinematics. It indicated that CR type can not reproduce such physiological motion without enough PCL. With PS type, femoral rollback was larger than CR type and it obtained wide range of motion. However, femur did not roll back over 90° of flexion angle. Moreover, contact force on post and cam increased much during deep knee flexion. If the PCL stiff enough, we should use the CR type. For PS type, it is necessary to design with consideration for acquiring femoral rollback and preventing breakage in the deep flex region.
本研究的目的是分析人工膝关节在深度屈曲时的静力学和运动学,以比较交叉保留(CR)型和后路稳定(PS)型的差异。我们在点接触和力/力矩平衡的条件下进行了三维模型分析。要进行的运动是膝关节被动屈曲,屈曲角度从30°到150°。结果表明,PS型髌骨股力和胫股力均小于CR型。此外,CR型在后交叉韧带(PCL)刚度较大时观察到股骨回退和胫骨内旋,通常观察到膝关节的生理运动学。说明如果没有足够的PCL, CR型细胞无法再现这种生理运动。PS型股骨回退比CR型大,运动范围宽。然而,股骨没有回滚超过90°的屈曲角。此外,在膝关节深度屈曲时,桩和凸轮的接触力增加了很多。如果PCL足够硬,我们应该使用CR型。对于PS型,在设计时要考虑到股骨回滚的获得和防止股骨深屈曲区断裂。
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引用次数: 0
Image Processing for X-ray Calibration Phantom x射线校准幻影的图像处理
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609973
Nutthanan Wanluk, C. Pintavirooj, T. Treebupachatsakul
Medical device calibration is the process of ensuring that there is accuracy before using. X-ray imaging device is one of the high-risk medical devices that must be calibrated. The calibration process required these values to be measured; center ray, focal object distance (FOD), resolution, and linearity of the imaging system. But the devices used to measure each of these are expensive. In this paper, a design of the x-ray calibration phantom that is affordable and yet effective is presented. An aluminum rectangular phantom consists of a center ray calibration unit, focal object distance (FOD) calibration unit and Linearity calibration unit. The x-ray image of all the phantom unit can be analyzed automatically by using the digital image processing.
医疗器械校准是在使用前确保其准确性的过程。x射线成像设备是必须进行校准的高风险医疗设备之一。校准过程需要测量这些值;成像系统的中心射线、焦距(FOD)、分辨率和线性度。但是用于测量这些的设备都很昂贵。本文提出了一种经济有效的x射线校准模体设计方案。铝制矩形模体由中心射线标定单元、焦距标定单元和线性标定单元组成。采用数字图像处理技术,可对所有虚体单元的x射线图像进行自动分析。
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引用次数: 2
The Comparison of The Biopsy Needles Efficiency 活检针效率的比较
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609957
S. Triviwatwong, A. Wongkamhamg, S. Boonyagun
Nowadays, the renal biopsy needles which used in Thailand have been imported from aboard. They are variety of brands, qualities and wide ranges of prices. Among the needles which are available in market, the biggest problem is renal needle effectiveness which affects to the volume of kidney for pathologic investigation. However, the use of biopsy needles depends on the satisfication of users which never been quantitatively identified. In this work, we performed the experiment to investigate the efficiency of biopsy needles, which focused on the Automatic and Disposable type from 5 brands (No.1 to No. 5). The tests were evaluated by 2 experiments; 1. The test of spring’s compressions with different compressive distances (10 mm., 15 mm. and 20 mm., respectively) and 2. The test of kidney volume was performed by punching the biopsy needle in porcine kidney with different angles of 15°, 30°, 45°, 60° and 75°, respectively. From the results of the spring’s compression, the needle No. 3, 5, 2, 1 and 4, respectively consumed the minimum to maximum forces in both parts of needle (cutter part and puncher part) at the maximum distance of 20 mm. The results from renal tissue volume test exhibited that at angle of 30° and 60° had constant volume of kidney, approximately 10 mm3, in each biopsy which is enough for volumic and pathologic conditions for pathology examination. In conclusion, results from the tests show that the 5 brands of biopsy needles have different technical design which affect to their effectiveness. However, they are still having the same general characteristic such as size and dimension which reported in the industrial standards.
目前,泰国使用的肾活检针都是从国外进口的。它们有各种牌子,各种质量,各种价格。目前市场上销售的肾针中,最大的问题是肾针的有效性,影响肾脏病理检查的体积。然而,活检针的使用取决于用户的满意度,这一点从未定量确定。在这项工作中,我们对活检针的效率进行了实验研究,重点研究了5个品牌(1号到5号)的自动和一次性类型。1. 不同压缩距离(分别为10 mm、15 mm和20 mm)下弹簧的压缩试验。肾体积的检测是将活检针分别以15°、30°、45°、60°、75°的不同角度在猪肾内打孔。从弹簧压缩结果来看,针3、针5、针2、针1、针4在最大距离为20mm处,针两部分(刀具部分和冲床部分)所消耗的力分别为最小到最大。肾组织体积检查结果显示,在角度为30°和60°时,每次活检的肾脏体积恒定,约为10 mm3,足以进行病理检查的体积和病理条件。综上所述,试验结果表明,5种品牌的活检针的技术设计不同,影响了其有效性。但是,它们仍然具有与工业标准中报告的尺寸和尺寸相同的一般特征。
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引用次数: 0
Enhanced Needle Detection in Ultrasound Images using Acoustic Excitation and Ultrasound Image Analyses 利用声激励和超声图像分析增强超声图像中的针检测
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609920
M. Daoud, Ahmad Shtaiyat, R. Alazrai
Ultrasound imaging provides a low cost and noninvasive imaging modality to improve the safety and success rate of needle-based interventions by guiding the needle towards the target anatomy. Nevertheless, the limited needle visibility in conventional brightness mode (B-mode) ultrasound images might degrade the capability of achieving accurate localization of the needle axis and tip. In this paper, a computer-based method is introduced to enable accurate needle detection in ultrasound images. In this method, the needle is excited using a voice actuator to generate low-amplitude acoustic waves that propagate through the needle. The excited needle is scanned using ultrasound imaging to acquire a power Doppler ultrasound image and a B-mode ultrasound image. The power Doppler image is processed using thresholding and Radon transform analyses to obtain approximate estimation of the needle axis and identify a region of interest (ROI) that includes the vibrating needle. Moreover, accurate estimation of the needle axis is achieved by analyzing the ROI that includes the needle in the B-mode image using a thresholding procedure combined with a customized Radon transform. Finally, the location of the needle tip is identified by applying an iterative sliding window approach to the B-mode image to quantify the pixel intensities around the estimated needle axis. The accuracy of the proposed method is evaluated by applying the method to detect the axes and tips of eight needles inserted in ex vivo bovine muscle tissue specimens and imaged using linear and curvilinear ultrasound transducers. The results show that the proposed method was able to detect the axes and tips of the inserted needles with error values within the ranges of 0.3° to 1.0° and 0.2 mm to 1.0 mm, respectively. These results suggest the potential of applying the proposed method to enhance the localization of the needle during ultrasound-guided needle-based interventions.
超声成像提供了一种低成本、无创的成像方式,通过引导针头指向目标解剖结构,提高针基干预的安全性和成功率。然而,在常规亮度模式(b模式)超声图像中,有限的针头可见性可能会降低实现针轴和针尖精确定位的能力。本文介绍了一种基于计算机的方法来实现超声图像中针的精确检测。在这种方法中,使用声音致动器激发针头以产生通过针头传播的低振幅声波。利用超声成像技术对受激针进行扫描,获得功率多普勒超声图像和b超图像。利用阈值分割和Radon变换分析对功率多普勒图像进行处理,得到针轴的近似估计,并确定包括振动针在内的感兴趣区域(ROI)。此外,通过使用阈值化程序结合自定义Radon变换分析b模式图像中包含针的ROI,实现了针轴的准确估计。最后,通过对b模式图像应用迭代滑动窗口方法来确定针尖的位置,以量化估计的针轴周围的像素强度。利用线性和曲线超声换能器对牛离体肌肉组织标本中插入的8根针的轴和尖端进行检测,评估了该方法的准确性。结果表明,该方法能够检测出插针的轴线和针尖,误差范围分别为0.3°~ 1.0°和0.2 mm ~ 1.0 mm。这些结果表明,在超声引导的针基干预中,应用所提出的方法来增强针的定位是有潜力的。
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引用次数: 2
Indirect Measure Voltage and Exposure Time Device for Medical X-ray 医用x射线间接测量电压和曝光时间装置
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609977
Manao Bunkum, C. Pintavirooj, S. Visitsattapongse
X-ray machine is used to create an image of diagnosing or treatment by using X-ray beam. X-ray beams are harmful to the body’s cells when the radiation dose is high enough. Therefore, the X-ray machine must always be calibrated or test to ensure that the X-ray machine is accurate to keep users safe. In this research presents the design and construction of x-ray testing device. It will focus on measuring the two main parameters of the x-ray machine. Measurement of exposure time (x-ray emission time) and measurements of peak kilovoltage from the x-ray tube. This device has 2 parts, hardware and software. The hardware is the circuit consist of intensifying screen for a radiation receiver and converted energy from x-ray into light energy. The wavelength of the light emitted is in the range of 500–600 nm, then use a circuit of photodiode. It is a semiconductor device that converts light into an electric current. The electric current is a full-wave rectification waveform corresponding to the 100 Hz high voltage supply of the x-ray tube. Take the signal from the electric current to filter circuit for reducing noise. And then take the signal to the microcontroller (Arduino). Arduino is used for taking the signal to process in Visual Studio program to measure exposure time and peak kilovoltage of x-ray, which can be measured and processed immediately. The waveform is digitized, and peak detected with Arduino. The number of peaks is then converted to exposure time, i.e. one peak corresponds to 10 milliseconds. The result, exposure time and peak kilovoltage of x-ray, will show on window form application in Visual Studio program.
x光机是利用x射线束形成诊断或治疗图像的仪器。当辐射剂量足够大时,x射线对人体细胞是有害的。因此,x光机必须经常进行校准或测试,以确保x光机的准确性,以保证用户的安全。本文介绍了x射线检测装置的设计与构造。它将着重于测量x光机的两个主要参数。曝光时间(x射线发射时间)的测量和x射线管峰值电压的测量。本设备由硬件和软件两部分组成。硬件部分是由用于辐射接收器的强化屏和将x射线能量转换为光能的电路组成。发射的光的波长在500 - 600nm范围内,然后使用光电二极管电路。它是一种将光转换成电流的半导体装置。电流为与x射线管100hz高压电源相对应的全波整流波形。从电流中提取信号到滤波电路中去噪。然后把信号送到微控制器(Arduino)。利用Arduino将需要在Visual Studio程序中处理的信号用于测量x射线的曝光时间和峰值千伏,可以立即进行测量和处理。波形被数字化,并用Arduino检测峰值。然后将峰值的数量转换为曝光时间,即一个峰值对应于10毫秒。结果,曝光时间和x射线的峰值电压,将在Visual Studio程序中以窗口形式显示。
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引用次数: 1
Investigation of Blood Hemolysis Study in Rotary Blood Pump between Continuous Flow and Pulsatile Flow 旋转血泵连续流动与脉动流动血液溶血的研究
Pub Date : 2018-11-01 DOI: 10.1109/BMEICON.2018.8609953
Chitsanupong Rungsirikunnan, Kamonwan Mondee, G. Gesprasert, P. Naiyanetr
Rotary blood pumps were used widely for medical treatment. Ventricular assist device (VAD) is one of the devices which based on rotary blood pump technology. Bridge to recovery (BTR) process is one of the treatment methods. VAD normally generate continuous blood flow. Latest report said that the pulsatile flow is better in blood vessel properties maintaining. However, VAD should not generated high shear stress that will cause the thrombosis. The objective of this study is to compare the hemolysis occur in rotary blood pump during constant speed and pulsatile speed. This study uses MOCK Circulation Loop to simulate the body circulatory system. The continuous flow and pulsatile flow will be compared. The rotary blood pump will be run at 1500 rpm constant speed and 1250–1750rpm, 1000–2000 rpm pulsatile speed at 60 beat per minute. The system was operated for 6 hours. The blood was obtained 1.5 milliliter from the loop every hour. The modified index of hemolysis (MIH) and plasma-free hemoglobin of each speed conditions were compared. The result shown that plasma-free hemoglobin levels in all speed condition increased with the duration of experiment. The MIH shown non significantly difference when the amplitude of pulsatile speed was increase. This experiment was preliminary study. In future work, the computational fluid dynamic software will use to simulated the phenomena inside the rotary blood pump and used for experiment compared.
旋转式血泵广泛用于医疗。心室辅助装置(VAD)是一种基于旋转血泵技术的装置。恢复桥法(BTR)是一种治疗方法。VAD通常会产生连续的血流。最新报道称,搏动血流在血管特性维持中较好。但VAD不应产生高剪切应力,以免引起血栓形成。本研究的目的是比较旋转血泵在恒定转速和脉动转速下发生的溶血。本研究使用MOCK Circulation Loop模拟人体循环系统。将对连续流和脉动流进行比较。旋转血泵将以1500 rpm恒定转速运行,1250-1750rpm, 1000-2000 rpm脉动速度每分钟60次。该系统运行了6小时。每小时从循环中取血1.5毫升。比较各速度条件下的改良溶血指数(MIH)和无血浆血红蛋白。结果表明,各转速条件下血浆游离血红蛋白水平均随实验时间延长而升高。随着脉动速度幅值的增加,MIH无显著差异。本实验为初步研究。在未来的工作中,计算流体动力学软件将用于模拟旋转血泵内部的现象,并用于实验比较。
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引用次数: 1
Automatic Lung Cancer Prediction from Chest X-ray Images Using the Deep Learning Approach 利用深度学习方法从胸部x射线图像中自动预测肺癌
Pub Date : 2018-08-31 DOI: 10.1109/BMEICON.2018.8609997
Worawate Ausawalaithong, S. Marukatat, Arjaree Thirach, Theerawit Wilaiprasitporn
Since, cancer is curable when diagnosed at an early stage, lung cancer screening plays an important role in preventive care. Although both low dose computed tomography (LDCT) and computed tomography (CT) scans provide greater medical information than normal chest x-rays, access to these technologies in rural areas is very limited. There is a recent trend toward using computer-aided diagnosis (CADx) to assist in the screening and diagnosis of cancer from biomedical images. In this study, the 121-layer convolutional neural network, also known as DenseNet-121 by G. Huang et. al., along with the transfer learning scheme is explored as a means of classifying lung cancer using chest x-ray images. The model was trained on a lung nodule dataset before training on the lung cancer dataset to alleviate the problem of using a small dataset. The proposed model yields 74.43±6.01% of mean accuracy, 74.96±9.85% of mean specificity, and 74.68±15.33% of mean sensitivity. The proposed model also provides a heatmap for identifying the location of the lung nodule. These findings are promising for further development of chest x-ray-based lung cancer diagnosis using the deep learning approach. Moreover, they solve the problem of a small dataset.
由于癌症在早期诊断是可以治愈的,因此肺癌筛查在预防保健中起着重要作用。虽然低剂量计算机断层扫描(LDCT)和计算机断层扫描(CT)比正常的胸部x光扫描提供更多的医学信息,但农村地区获得这些技术的机会非常有限。最近有一种趋势是使用计算机辅助诊断(CADx)来帮助从生物医学图像中筛选和诊断癌症。在这项研究中,121层卷积神经网络(也被G. Huang等人称为DenseNet-121)以及迁移学习方案被探索作为使用胸部x射线图像对肺癌进行分类的一种手段。该模型在肺癌数据集训练之前先在肺结节数据集上进行训练,以缓解使用小数据集的问题。该模型的平均准确率为74.43±6.01%,平均特异性为74.96±9.85%,平均灵敏度为74.68±15.33%。提出的模型还提供了一个热图,以确定肺结节的位置。这些发现对于使用深度学习方法进一步发展基于胸部x线的肺癌诊断有希望。此外,它们还解决了数据集小的问题。
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引用次数: 98
期刊
2018 11th Biomedical Engineering International Conference (BMEiCON)
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