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A comparison of oral versus vaginal misoprostol for induction of labor at term, at the Ahmadu Bello University Teaching Hospital, Zaria 口服米索前列醇与阴道米索前列醇用于足月引产的比较,在Zaria的Ahmadu Bello大学教学医院
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_27_19
S. Hauwa, S. Shittu, H. Umar-Sulayman, B. Audu
Background: The comparison of same,equal and low dose of misoprostol by the oral and vaginal routes for induction of labour at term requires further elucidation. Objective: To compare the efficacy and safety of 25 micrograms (ug) of oral misoprostol with 25ug vaginal misoprostol for induction of labor at term. Methods: A randomised control trial that involved 169 consented women with indication for induction of labor. A total of 85 women had oral misoprostol while 84 women had vaginal misoprostol. The oral misoprostol dose (25ug) was repeated every 2 hours, while the vaginal dose (25ug) was repeated every 6 hours for a maximum duration of 24 hours or when need arose for intervention. Data was analysed using SPSS version 20. Results: The mean induction-delivery interval was significantly shorter (18.48 +/- 2.01 vs. 22.82 +/- 2.50, P = 0.00), with more vaginal deliveries (88.2% vs. 85.7%, P = 0.00) in the oral group compared to the vaginal group respectively. The cardiotocographic abnormalities in the vaginal group were significantly higher than the oral group (8.3% vs. 1.2%, P = 0.03). There were more foetal distress and meconium stained liquor in the vaginal group but not statistically significant.
背景:通过口服和阴道途径对相同、相等和低剂量的米索前列醇进行足月引产的比较需要进一步阐明。目的:比较25微克口服米索前列醇和25微克阴道米索前列用于足月引产的疗效和安全性。方法:一项随机对照试验,涉及169名同意引产的女性。共有85名妇女口服米索前列醇,84名妇女阴道服用米索前列。口服米索前列醇剂量(25μg)每2小时重复一次,而阴道剂量(25µg)每6小时重复一一次,最长持续时间为24小时或需要干预时。使用SPSS版本20对数据进行分析。结果:与阴道组相比,口服组的平均引产间隔显著缩短(18.48+/-2.01 vs.22.82+/-2.50,P=0.00),阴道分娩次数分别增加(88.2%vs.85.7%,P=0.000)。阴道组的心分娩异常明显高于口服组(8.3%对1.2%,P=0.03)。阴道组的胎儿窘迫和胎粪染色液较多,但无统计学意义。
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引用次数: 3
Outcome of induction of labor with prostaglandin E1 25 mg vaginal tablet – A retrospective study 前列腺素E1 25mg阴道片引产效果的回顾性研究
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_24_19
G. Puliyath, A. Balakrishnan, L. Vinod, H. Hameed
Context: Labor induction with prostaglandin E1 (PGE1) vaginal tablet results in shorter induction delivery interval and decreased rate of failed induction of labor and reduced caesarean section rate. However, higher doses may be associated with uterine hyper stimulation. It is therefore necessary to determine the safe dose of PGE1 for labor induction. Aims: To assess the maternal and neonatal outcome with use of 25 mg vaginal misoprostol for induction of labor. Settings and Design: A retrospective analysis conducted in an obstetric department of a tertiary care teaching institute. Materials and Methods: The sample consists of women with singleton term pregnancy, with Bishop's score <6 compared with women with spontaneous onset of labor. Statistical Analysis Used: Statistical significance was assessed at 5% level of significance. Chi-square test, with correction for continuity where applicable, was carried out to compare proportions across subgroups or between induction and spontaneous onset groups. Results: The rate of vaginal delivery was higher among spontaneous onset group compared with induction group (χ2 (1) = 30.3, P < 0.001). The induction delivery interval of vaginal delivery was less than 24 h in 91.85% of women. Neonatal intensive care unit admission frequency was similar among both groups (χ2 (1) = 0.14, P = 0.704). The induction group was with less frequency of meconium staining than the control group (χ2 (1) = 8.05, P = 0.0046). Conclusion: Our study showed a higher rate of vaginal delivery with induction delivery interval less than 24 h in a majority of women with better neonatal and maternal outcomes.
背景:前列腺素E1阴道片引产可缩短引产间隔,降低引产失败率,降低剖宫产率。然而,较高的剂量可能与子宫过度刺激有关。因此,有必要确定用于引产的PGE1的安全剂量。目的:评估使用25mg阴道米索前列醇引产的产妇和新生儿结局。设置和设计:一项在高等护理教学机构产科进行的回顾性分析。材料和方法:样本由单胎足月妊娠的妇女组成,与自然分娩的妇女相比,Bishop评分<6。使用的统计分析:统计显著性评估为5%的显著性水平。卡方检验,在适用的情况下对连续性进行校正,以比较亚组之间或诱导组和自发发作组之间的比例。结果:自然分娩组的阴道分娩率高于引产组(χ2(1)=30.3,P<0.001),91.85%的妇女阴道分娩的引产间隔小于24小时。两组新生儿重症监护病房入院频率相似(χ,P=0.0046)。结论:我们的研究表明,在大多数新生儿和产妇预后较好的妇女中,引产间隔小于24小时的阴道分娩率较高。
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引用次数: 0
Maternal death surveillance and response system in Northern Nigeria 尼日利亚北部孕产妇死亡监测和反应系统
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_73_18
S. Ochejele, J. Musa, MJ Abdullahi, P. Odusolu, Attah Di, G. Alobo
Introduction: The maternal death surveillance and response (MDSR) responds to MDG 5 and Sustainable development goal 3. It was designed to achieve this goal by obtaining and strategically using information to guide public health actions and monitoring their impact. Objective: To determine the burden and avoidable causes of maternal mortality in midwives service scheme (MSS) communities in Northern Nigeria. Methodology: This was a cross-sectional study using baseline MDSR data on confidential enquiry into maternal deaths in all health facilities and their host communities under the MSS in Northern Nigeria from July 1st to December 31st, 2011. Results: The MMR was 181/100,000 live births. Most (80.9%) of the deaths were due to direct obstetric complications with obstetric hemorrhage and eclampsia accounting for 66.6% of the deaths. Most deaths occurred postpartum (93.6%) with the first 48 h accounting for 85.1% of cases. At presentation, 76.5% were in critical conditions. The TBAs conducted 50.0% of the deliveries. Delays in decision making contributed to 51 (63.8%), delay in arriving at the facility accounted for 48 (60.0%), financial constraints 28 (35.0%), unsafe traditional practice 27 (33.8%), and use of traditional medicines 22 (27.5%). The TBA failed to refer early in 42 (52.5%), failed to recognize dangers signs in 27 (33.8%). Stillbirths occurred in 22.2% of cases. Conclusion: Most maternal deaths in Northern Nigeria are preventable. Operational research using the MDSR is very useful in determining the causes and designing appropriate response to maternal deaths at the community level in Nigeria.
产妇死亡监测和应对(MDSR)响应千年发展目标5和可持续发展目标3。它旨在通过获取和战略性地利用信息来指导公共卫生行动并监测其影响,从而实现这一目标。目的:确定尼日利亚北部助产士服务计划(MSS)社区孕产妇死亡的负担和可避免的原因。方法:这是一项横断面研究,使用2011年7月1日至12月31日期间尼日利亚北部MSS下所有卫生设施及其收容社区孕产妇死亡保密调查的基线MDSR数据。结果:MMR为181/10万活产。大多数(80.9%)死亡是由于直接产科并发症,产科出血和子痫占死亡人数的66.6%。大多数死亡发生在产后(93.6%),其中前48小时占85.1%。报告时,76.5%的患者处于危急状态。tba进行了50.0%的交付。决策延误造成51例(63.8%),到达设施延误造成48例(60.0%),财政限制造成28例(35.0%),不安全传统做法造成27例(33.8%),使用传统药物造成22例(27.5%)。TBA未能及早发现42例(52.5%),未能识别危险信号27例(33.8%)。死产发生率为22.2%。结论:尼日利亚北部大多数孕产妇死亡是可以预防的。使用千年发展战略的业务研究在尼日利亚社区一级确定产妇死亡原因和设计适当对策方面非常有用。
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引用次数: 2
Awareness and knowledge of cervical cancer and its screening methods among women attending primary healthcare centers in Zaria, North-Western, Nigeria 尼日利亚西北部扎里亚初级保健中心妇女对癌症及其筛查方法的认识和知识
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_26_19
A. Yahya, A. Mande
Background: Cervical cancer is a leading cause of cancer death in many developing countries. Cervical cancer can be prevented by screening and treatment of premalignant lesions of the cervix. Primary healthcare centers are the health centers closest to the grassroots in Nigeria and thus may be appropriate for population-based cervical cancer screening programs. This study sought to assess awareness of cervical cancer and its screening methods among women attending primary healthcare centers in Zaria, Nigeria. Methodology: It was a cross-sectional study. Participants were women accessing healthcare in primary healthcare centers in Zaria. Eight primary healthcare centers in Zaria were purposively selected for the study. Data were obtained by focus group discussions (FGDs). The FGDs were tape-recorded and transcribed verbatim. The transcripts obtained were analyzed into themes based on the objectives of the study. Results: The mean age of respondents was 26 years (standard deviation 4.9 years). Many participants were aware of symptoms of cervical cancer; however, they were not aware of the risk factors. Pap smear was the only screening method known to participants. Conclusion: Awareness of cervical cancer and cervical screening did not reflect adequate knowledge about cervical cancer and screening methods. There is a need for healthcare providers to offer adequate health education about the disease and screening methods.
背景:癌症是许多发展中国家癌症死亡的主要原因。癌症可以通过筛查和治疗宫颈癌前病变来预防。初级医疗保健中心是尼日利亚最接近基层的医疗保健中心,因此可能适合开展基于人群的癌症宫颈筛查项目。这项研究旨在评估尼日利亚扎里亚初级保健中心女性对癌症及其筛查方法的认识。方法:这是一项横断面研究。参与者是在扎里亚初级保健中心获得保健的妇女。扎里亚的八个初级保健中心被有意选择用于这项研究。数据通过焦点小组讨论获得。FGD被录音并逐字转录。根据研究目标,将获得的转录本分为主题进行分析。结果:调查对象的平均年龄为26岁(标准差为4.9岁)。许多参与者都知道癌症的症状;然而,他们没有意识到风险因素。巴氏涂片是参与者已知的唯一筛查方法。结论:对宫颈癌症和宫颈筛查的认识不能充分反映对癌症和筛查方法的认识。医疗保健提供者需要提供有关疾病和筛查方法的充分健康教育。
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引用次数: 7
Awareness, attitude and use of labor analgesics by pregnant women at State Specialist Hospital, Akure 阿库雷国立专科医院孕妇对分娩镇痛药的认识、态度和使用情况
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_92_18
R. Omotayo, OR Akinsowon, S. Omotayo
Background: Pain relief during labor has always been associated with myths and controversies. Several groups of people think that God has made this process painful and no interference should be done in it. In the present civilization, there is no circumstance where it is considered acceptable for a person to experience severe pain, amenable to safe intervention while under a physician's care. Objective: This study assessed the level of awareness of pregnant women about labor analgesia and factors preventing them from having analgesia in labor. Study Design: This study is a descriptive cross-sectional study. Methodology: Questionnaires were used to obtain information on awareness, attitude and use of labor analgesia from pregnant women at the booking clinic visit. Three hundred (300) consenting pregnant women were recruited into the study including provision for attrition. Data were analyzed with the Statistical Package for Social sciences (SPSS) 20. Proportions were calculated for independent variables while crosstabulation was done for related variables to find P value for statistical significance. Results: Level of awareness of labor analgesia was 21%. Majority of the respondents (70.3%) believe that among all health professionals, it is doctors that should inform them about labor analgesia. Only 4.4% had used labor analgesic in their previous deliveries. About 81% of respondents desire labor analgesia in their next delivery. Among factors analyzed, only severity of last labor had significant influence on the patient's desire for analgesia in their next delivery (P value = 0.026). Conclusion: The awareness rate of pregnant women about labor analgesia is very low. Therefore, all efforts must be made to ensure that discussions about labor analgesia are commenced as early as at the booking visit to improve on pregnant women's awareness about labor analgesia and help their acceptability and choices. Attitude towards labor analgesia is not influenced by type of facility where the delivery took place suggesting possibility of socio-cultural influence of the people in the area of study on the practice of labor analgesia.
背景:分娩镇痛一直与神话和争议有关。一些人认为上帝让这个过程很痛苦,不应该干涉。在当今的文明中,没有任何一种情况可以让一个人在医生的护理下经历剧烈的疼痛,可以进行安全的干预。目的:了解孕妇对分娩镇痛的认知水平及影响分娩镇痛的因素。研究设计:本研究为描述性横断面研究。方法:采用问卷调查的方式,了解预约就诊孕妇对分娩镇痛的认知、态度和使用情况。三百(300)名同意怀孕的妇女被招募到研究中,包括减员准备。数据分析采用社会科学统计软件包(SPSS) 20。对自变量进行比例计算,对相关变量进行交叉拟合,求P值具有统计学显著性。结果:分娩镇痛知知率为21%。大多数受访者(70.3%)认为,在所有卫生专业人员中,医生应该告诉他们有关分娩镇痛的知识。只有4.4%的产妇在之前的分娩中使用过镇痛药。约81%的受访者希望在下次分娩时镇痛。在分析的因素中,只有上一次分娩的严重程度对患者下次分娩时的镇痛意愿有显著影响(P值= 0.026)。结论:产妇对分娩镇痛的知晓率很低。因此,必须尽一切努力确保早在预约就诊时就开始讨论分娩镇痛,以提高孕妇对分娩镇痛的认识,帮助她们接受和选择。对分娩镇痛的态度不受分娩场所类型的影响,这表明研究区域的人们可能对分娩镇痛的实践产生社会文化影响。
{"title":"Awareness, attitude and use of labor analgesics by pregnant women at State Specialist Hospital, Akure","authors":"R. Omotayo, OR Akinsowon, S. Omotayo","doi":"10.4103/TJOG.TJOG_92_18","DOIUrl":"https://doi.org/10.4103/TJOG.TJOG_92_18","url":null,"abstract":"Background: Pain relief during labor has always been associated with myths and controversies. Several groups of people think that God has made this process painful and no interference should be done in it. In the present civilization, there is no circumstance where it is considered acceptable for a person to experience severe pain, amenable to safe intervention while under a physician's care. Objective: This study assessed the level of awareness of pregnant women about labor analgesia and factors preventing them from having analgesia in labor. Study Design: This study is a descriptive cross-sectional study. Methodology: Questionnaires were used to obtain information on awareness, attitude and use of labor analgesia from pregnant women at the booking clinic visit. Three hundred (300) consenting pregnant women were recruited into the study including provision for attrition. Data were analyzed with the Statistical Package for Social sciences (SPSS) 20. Proportions were calculated for independent variables while crosstabulation was done for related variables to find P value for statistical significance. Results: Level of awareness of labor analgesia was 21%. Majority of the respondents (70.3%) believe that among all health professionals, it is doctors that should inform them about labor analgesia. Only 4.4% had used labor analgesic in their previous deliveries. About 81% of respondents desire labor analgesia in their next delivery. Among factors analyzed, only severity of last labor had significant influence on the patient's desire for analgesia in their next delivery (P value = 0.026). Conclusion: The awareness rate of pregnant women about labor analgesia is very low. Therefore, all efforts must be made to ensure that discussions about labor analgesia are commenced as early as at the booking visit to improve on pregnant women's awareness about labor analgesia and help their acceptability and choices. Attitude towards labor analgesia is not influenced by type of facility where the delivery took place suggesting possibility of socio-cultural influence of the people in the area of study on the practice of labor analgesia.","PeriodicalId":23302,"journal":{"name":"Tropical Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48570369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Unwanted pregnancy and induced abortion among female undergraduates in University of Ibadan, Nigeria 尼日利亚伊巴丹大学女大学生的意外怀孕和人工流产
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_35_19
Chinedum C Onebunne, F. Bello
Objectives: To assess the prevalence of unwanted pregnancies and induced abortion among female undergraduates. Methodology: A cross-sectional survey was conducted among female undergraduates in University of Ibadan, Nigeria. The survey used a structured, self-administered questionnaire. Data analysis was conducted using Statistical Package for the Social Sciences version 20 with Chi-square and t-tests. Statistical significance was set at P < 0.05. Findings: The mean age of the participants was 20.3 (±2.7) years and 80% were single at the time of the study. The prevalence of induced abortion was 51%. The overall prevalence of unwanted pregnancy was 17%, and 92.7% of students who had ever been pregnant had considered the pregnancy unwanted. Only 7.3% reported willingness to be pregnant while engaged and 58.3% were unwilling to keep pregnancy if engagement ends. Unwanted pregnancy was less among those ever married (χ2 = 49.96, P < 0.001), and more of the induced abortions were found in the unmarried group albeit not statistically significant (χ2 = 0.21, P = 0.640). Unwanted pregnancy occurred more during the engaged period than any other time, which was statistically significant (χ2 = 20.24, P < 0.001), although no significant difference in induced abortion was found. Conclusion: The prevalence of unwanted pregnancy and induced abortion is high especially among university undergraduates. As it appears to happen more often while they are engaged, unprotected sex during the engagement period needs to be targeted.
目的:评估女大学生意外怀孕和人工流产的发生率。方法:对尼日利亚伊巴丹大学的女本科生进行了一项横断面调查。这项调查采用了一份结构化的、自我管理的问卷。使用社会科学版20的统计软件包进行数据分析,并进行卡方检验和t检验。统计学显著性为P<0.05。研究结果:参与者的平均年龄为20.3(±2.7)岁,研究时80%为单身。人工流产的发生率为51%。意外怀孕的总体患病率为17%,92.7%的曾怀孕的学生认为意外怀孕。只有7.3%的人表示愿意在订婚时怀孕,58.3%的人不愿意在订婚结束后继续怀孕。未婚者中意外怀孕较少(χ2=49.96,P<0.001),未婚者中人工流产较多,但无统计学意义(χ2=0.21,P=0.640)。意外怀孕发生在订婚期间比任何其他时间都多,具有统计学意义(ω2=20.24,P<001),尽管在人工流产方面没有发现显著差异。结论:非意愿妊娠和人工流产的发生率较高,尤其是在大学生中。由于这种情况似乎更经常发生在订婚期间,因此需要针对订婚期间的无保护性行为。
{"title":"Unwanted pregnancy and induced abortion among female undergraduates in University of Ibadan, Nigeria","authors":"Chinedum C Onebunne, F. Bello","doi":"10.4103/TJOG.TJOG_35_19","DOIUrl":"https://doi.org/10.4103/TJOG.TJOG_35_19","url":null,"abstract":"Objectives: To assess the prevalence of unwanted pregnancies and induced abortion among female undergraduates. Methodology: A cross-sectional survey was conducted among female undergraduates in University of Ibadan, Nigeria. The survey used a structured, self-administered questionnaire. Data analysis was conducted using Statistical Package for the Social Sciences version 20 with Chi-square and t-tests. Statistical significance was set at P < 0.05. Findings: The mean age of the participants was 20.3 (±2.7) years and 80% were single at the time of the study. The prevalence of induced abortion was 51%. The overall prevalence of unwanted pregnancy was 17%, and 92.7% of students who had ever been pregnant had considered the pregnancy unwanted. Only 7.3% reported willingness to be pregnant while engaged and 58.3% were unwilling to keep pregnancy if engagement ends. Unwanted pregnancy was less among those ever married (χ2 = 49.96, P < 0.001), and more of the induced abortions were found in the unmarried group albeit not statistically significant (χ2 = 0.21, P = 0.640). Unwanted pregnancy occurred more during the engaged period than any other time, which was statistically significant (χ2 = 20.24, P < 0.001), although no significant difference in induced abortion was found. Conclusion: The prevalence of unwanted pregnancy and induced abortion is high especially among university undergraduates. As it appears to happen more often while they are engaged, unprotected sex during the engagement period needs to be targeted.","PeriodicalId":23302,"journal":{"name":"Tropical Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48271782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The incidence of retained fetal bones after 1,002 hysteroscopies in an environment with restrictive abortion laws 在限制堕胎的环境中进行1002次宫腔镜检查后保留胎儿骨骼的发生率
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_91_18
J. Okohue
Background: Retained fetal bones within the uterine cavity are rare. The incidence in an environment with restrictive abortion laws is however unknown. Aim: To document the incidence of retained fetal bones in an environment with highly restrictive abortion laws. Methods: Case records of patients who had hysteroscopy on account of retained fetal bones from April 1, 2010 to March 31, 2017 were retrieved. Data including age, number of terminations of pregnancy, gestational age at termination of pregnancy, duration of infertility, and treatment outcome were retrieved. Results: A total of 1,002 patients had hysteroscopy for various indications. Of these, 26 patients had retained fetal bones giving an incidence of 0.26%. The age range of the patients was 28--42 years, mean 34.7 ± 4.6 SD. Duration of infertility ranged from 2 to 8 years, mean 4.6 ± 2.3 SD. The number of terminations of pregnancy ranged from 1 to 6, mean 2.6 ± 1.7 SD. One patient had an unexplained intrauterine fetal death of one of a set of twins at 20 weeks gestation with subsequent elective cesarean section at 37 weeks gestation. All the cases had histological confirmation of fetal bones. Of the 24 patients who had secondary infertility, 6 (25.0%) achieved spontaneous pregnancies. Eight women underwent in vitro fertilization treatment with 2 (25%) clinical pregnancies. Conclusion: The incidence of intrauterine retained fetal bones in our environment with highly restrictive abortion laws is 0.26%. A review of these laws is probably long overdue.
背景:保留在子宫腔内的胎儿骨骼是罕见的。然而,在有限制性堕胎法的环境中发生率是未知的。目的:记录在堕胎法严格限制的环境中保留胎儿骨骼的发生率。方法:检索2010年4月1日至2017年3月31日因胎儿骨骼残留而行宫腔镜检查的患者的病例记录。检索包括年龄、终止妊娠次数、终止妊娠时的胎龄、不孕持续时间和治疗结果在内的数据。结果:共有1002例患者因各种适应症接受了宫腔镜检查。其中26例患者保留了胎儿骨骼,发生率为0.26%。患者年龄范围为28-42岁,平均34.7±4.6 SD。不孕持续时间为2-8岁,平均4.6±2.3 SD。终止妊娠次数为1-6次,平均2.6±1.7 SD。一名患者在妊娠20周时,一对双胞胎中的一对出现不明原因的宫内胎儿死亡,随后在妊娠37周时进行了选择性剖宫产。所有病例均有胎儿骨骼的组织学证实。在24例继发性不孕患者中,6例(25.0%)实现了自然妊娠。8名妇女接受了体外受精治疗,其中2名(25%)临床妊娠。结论:在我们严格限制堕胎的环境中,宫内保留胎儿骨骼的发生率为0.26%。对这些法律的审查可能早就应该了。
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引用次数: 4
A stone age conduct of unsafe abortion in adolescent: Complicated by gangrenous uterus and bowel 青少年结石年龄不安全流产行为:并发子宫和肠道坏疽
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_15_19
B. Olofinbiyi, J. Ige, O. Olaogun, O. Alao, O. Adewumi, R. Olofinbiyi
Unsafe abortion in adolescents is of great public health challenge and it occupies a large armamentarium in contemporary adolescent reproductive health issues. This case report was that of induced unsafe abortion, done without analgesia and inside a sitting room, in a 15-year-old, secondary school girl, nullipara; complicated by gangrenous uterus and bowel for which she had subtotal hysterectomy, bowel resection, and anastomosis. Primary preventive strategies should be the cornerstone of prevention with more emphasis on advocacy for adolescent sexuality and reproductive health education, information, and family planning/emergency contraception.
青少年不安全堕胎是一项巨大的公共卫生挑战,在当代青少年生殖健康问题上占据了很大的份额。该病例报告是一名15岁的中学生在没有镇痛的情况下在客厅内进行的不安全人工流产;并发子宫和肠道坏疽,为此她进行了子宫次全切除术、肠道切除术和吻合。初级预防战略应成为预防的基石,更加重视倡导青少年性行为和生殖健康教育、信息以及计划生育/紧急避孕。
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引用次数: 1
Clinical improvement of status epilepticus after delivery: A case report 产后癫痫持续状态的临床改善1例
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_2_19
C. Obikili, Makshwar L. Kahansim, A. Ocheke
Status epilepticus is a rare neurological complication of pregnancy, associated with significant maternal and fetal morbidity and mortality. Termination of pregnancy is not currently a management strategy. The clinical case was 35-year-old known epileptic presented with complaints of multiple convulsions of 2 days and loss of consciousness of a day. On examination, she was unconscious, with Glasgow Coma Scale 5/15, having repeated seizures, and blood pressure was normal. The assessment was status epilepticus and she was shortly admitted into the intensive care unit. She was eventually paralyzed and put on mechanical ventilation. She had a spontaneous delivery, subsequently improved, and was discharged on oral carbamazepine. Key aspects of this patient's management buttressed that status epilepticus can mimic eclampsia. That she significantly and progressively improved following delivery and that previous similar cases have been reported brings to bear that delivery might need to be considered as a management strategy for refractory status epilepticus.
癫痫持续状态是一种罕见的妊娠神经系统并发症,与显著的母体和胎儿发病率和死亡率相关。终止妊娠目前不是一种管理策略。临床病例35岁,已知癫痫患者,主诉多次惊厥2天,意识丧失1天。经检查,她昏迷,格拉斯哥昏迷评分为5/15,反复发作,血压正常。评估结果是癫痫持续状态,她很快就住进了重症监护室。她最终瘫痪了,需要使用机械通气。她自然分娩,随后好转,出院时口服卡马西平。该患者管理的关键方面支持癫痫持续状态可以模仿子痫。分娩后病情显著且逐渐好转,以及以前报道的类似病例表明,分娩可能需要被视为难治性癫痫持续状态的一种管理策略。
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引用次数: 1
Relationship between 25-hydroxyvitamin D and ovarian reserve in premenopausal Nigerian women 尼日利亚绝经前妇女25-羟基维生素D与卵巢储备的关系
Pub Date : 2019-05-01 DOI: 10.4103/TJOG.TJOG_99_18
C. Makwe, Z. Aliyu
Context: Despite the increasing knowledge about the potential effect of vitamin D deficiency on ovarian reserve of premenopausal women, the burden of this disorder among 'at risk' women in sub-Saharan Africa is notably scanty. Aims: To determine the prevalence of vitamin D deficiency among premenopausal Nigerian women To assess the relationship between serum 25-hydroxyvitamin D [25(OH)D] and serum anti-mullerian hormone (AMH). Settings and Design: A prospective cross-sectional study of 218 premenopausal Nigerian women, attending a tertiary hospital in Lagos. Materials and Methods: Serum levels of 25(OH)D and AMH were assayed using ELIZA technique, for each eligible participant. Statistical Analysis Used: To determine the association between serum vitamin D and serum AMH were Kruskal-Wallis test and Pearson's correlation coefficient. Data analysis was performed on 211 participants with complete data. Results: The mean (± SD) concentrations of serum 25(OH)D and AMH were 37.8 (± 21.4) ng/ml and 1.6 (± 0.6) ng/ml, respectively. The proportion of study participants with serum vitamin D deficiency, insufficiency and sufficiency were 18.5%, 24.6%, and 56.9%, respectively. There was no statistically significant difference in the mean serum AMH among participants with deficient, insufficient, and sufficient vitamin D levels (1.41 ng/ml versus 1.56 ng/ml versus 1.59 ng/ml, P value = 0.539). Overall, there was no correlation between serum 25(OH)D, and serum AMH (r = 0.056, P > 0.05). Conclusion: Although the proportion of women with subnormal levels of serum vitamin D was relatively high, there was no association between serum levels of vitamin D and AMH.
背景:尽管关于维生素D缺乏对绝经前妇女卵巢储备的潜在影响的知识越来越多,但在撒哈拉以南非洲的“高危”妇女中,这种疾病的负担明显很少。目的:了解尼日利亚绝经前妇女维生素D缺乏症的患病率,评估血清25-羟基维生素D [25(OH)D]与血清抗苗勒管激素(AMH)的关系。背景和设计:对在拉各斯一家三级医院就诊的218名尼日利亚绝经前妇女进行前瞻性横断面研究。材料和方法:采用ELIZA技术检测每位符合条件的受试者血清25(OH)D和AMH水平。统计学分析方法:采用Kruskal-Wallis检验和Pearson相关系数测定血清维生素D与血清AMH的关系。对211名数据完整的参与者进行数据分析。结果:血清25(OH)D和AMH的平均(±SD)浓度分别为37.8(±21.4)ng/ml和1.6(±0.6)ng/ml。血清维生素D缺乏、不足和充足的比例分别为18.5%、24.6%和56.9%。维生素D缺乏、不足和充足的参与者的平均血清AMH差异无统计学意义(1.41 ng/ml vs 1.56 ng/ml vs 1.59 ng/ml, P值= 0.539)。总体而言,血清25(OH)D与血清AMH无相关性(r = 0.056, P < 0.05)。结论:虽然血清维生素D水平低于正常的女性比例较高,但血清维生素D水平与AMH之间没有相关性。
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引用次数: 2
期刊
Tropical Journal of Obstetrics and Gynaecology
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